<PAGE>
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13D
Under the Securities Exchange Act of 1934
(Amendment No. 22)
CYPRESS BIOSCIENCE INCORPORATED
(Name of Issuer)
Common Stock $0.02 Par Value
(Title of Class of Securities)
449695303
(CUSIP Number)
Allen & Company Incorporated
711 Fifth Avenue, New York, New York 10022, (212) 832-8000
(Name, Address and Telephone Number of Person Authorized
to Receive Notices and Communications)
October 3, 1997
(Date of Event which Requires Filing of this Statement)
If the filing person has previously filed a statement on Schedule 13G
to report the acquisition which is the subject of this Schedule 13D,
and is filing this schedule because of Rule 13-d-1(b)(3) or (4), check
the following box [ ].
Check the following box if a fee is being paid with the statement [ ].
(A fee is not required only if the reporting person: (1) has a
previous statement on file reporting beneficial ownership of more than
five percent of the class of securities described in Item 1; and (2)
has filed no amendment subsequent thereto reporting beneficial
ownership of five percent or less of such class.) (See Rule 13d-7.)
Note: Six copies of this statement, including all exhibits, should be
filed with the Commission. See Rule 13d-1(a) for other parties to
whom copies are to be sent.
* The remainder of this cover page shall be filled out for a
reporting person's initial filing on this form with respect to the
subject class of securities, and for any subsequent amendment
containing information which would alter disclosures provided in a
prior cover page.
The information required on the remainder of this cover page shall not
be deemed to be "filed" for the purposes of Section 18 of the
Securities Exchange Act of 1934 ("Act") or otherwise subject to the
liabilities of that section of the Act but shall be subject to all
other provisions of the Act (however, see the Notes).
Page 1 of 35 Pages<PAGE>
<PAGE>
SCHEDULE 13D
- --------------------- -----------------
CUSIP No. 449695303 Page 2 of 35 Pages
- --------------------- -----------------
===========================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
ALLEN HOLDING INC.
- --------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
- ---------------------------------------------------------------------------
3 SEC USE ONLY
- ---------------------------------------------------------------------------
4 SOURCE OF FUNDS*
Not Applicable
- ---------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(E) [ ]
- ---------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
- ---------------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
- --------------------------------------------------------------------------
7 SOLE VOTING POWER
0
- ---------------------------------------------------------------------------
8 SHARED VOTING POWER
0
- --------------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
0
- ---------------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
- ---------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
0
- ---------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [X]
Excluding 5,829,698 shares (includes 125,000 Units and a total of
228,000 Common Stock Purchase Warrants, owned by Allen & Company
Incorporated, a wholly-owned subsidiary. Each Unit consists of two
shares of Common Stock and one Common Stock Purchase Warrant.)
- ---------------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
0.0%
- ---------------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
HC
===========================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!<PAGE>
<PAGE>
SCHEDULE 13D
- --------------------- -----------------
CUSIP No. 449695303 Page 3 of 35 Pages
- --------------------- -----------------
===========================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
ALLEN & COMPANY INCORPORATED
- --------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
- ---------------------------------------------------------------------------
3 SEC USE ONLY
- ---------------------------------------------------------------------------
4 SOURCE OF FUNDS*
WC
- ---------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(e) [ ]
- ---------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
New York
- ---------------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
- --------------------------------------------------------------------------
7 SOLE VOTING POWER
5,829,698 Shares (includes 125,000 Units and a total of 228,000 Common
Stock Purchase Warrants. Each Unit consists of two shares of Common
Stock and one Common Stock Purchase Warrant.)
- ---------------------------------------------------------------------------
8 SHARED VOTING POWER
0
- --------------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
5,829,698 Shares (includes 125,000 Units and a total of 228,000 Common
Stock Purchase Warrants. Each Unit consists of two shares of Common
Stock and one Common Stock Purchase Warrant.)
- ---------------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
- ---------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
5,829,698 Shares (includes 125,000 Units and a total of 228,000 Common
Stock Purchase Warrants. Each Unit consists of two shares of Common
Stock and one Common Stock Purchase Warrant.)
- ---------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [X]
- ---------------------------------------------------------------------------
13 PERCENT O CLASS REPRESENTED BY AMOUNT IN ROW (11) 16.5%
- ---------------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
BC,CO
===========================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!<PAGE>
<PAGE>
SCHEDULE 13D
- --------------------- ------------------
CUSIP No. 449695303 Page 4 of 35 Pages
- --------------------- --------------------
==========================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
The Estate of Herbert A. Allen
- ---------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
- ---------------------------------------------------------------------------
3 SEC USE ONLY
- ---------------------------------------------------------------------------
4 SOURCE OF FUNDS*
Not Applicable
- ---------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(E) [ ]
- ---------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- ---------------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
- ---------------------------------------------------------------------------
7 SOLE VOTING POWER
599,359
- ---------------------------------------------------------------------------
8 SHARED VOTING POWER
0
- ---------------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
599,359
- ---------------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
- ---------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
599,359
- ---------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [ ]
- ---------------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
1.7%
- ---------------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
IN
===========================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!
SEC 1746 (9-88)<PAGE>
<PAGE>
SCHEDULE 13D
- --------------------- ------------------
CUSIP No. 449695303 Page 5 of 35 Pages
- --------------------- -------------------
==========================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Irwin Kramer
- ---------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
- ---------------------------------------------------------------------------
3 SEC USE ONLY
- ---------------------------------------------------------------------------
4 SOURCE OF FUNDS*
Not Applicable
- ---------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(E) [ ]
- ---------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- ---------------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
- ---------------------------------------------------------------------------
7 SOLE VOTING POWER
11,268
- ---------------------------------------------------------------------------
8 SHARED VOTING POWER
0
- ---------------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
11,268
- ---------------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
- ---------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
11,268
- ---------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [ ]
- ---------------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
Less than 0.1%
- ---------------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
IN
===========================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!
SEC 1746 (9-88)<PAGE>
<PAGE>
SCHEDULE 13D
- --------------------- ------------------
CUSIP No. 449695303 Page 6 of 35 Pages
- --------------------- -------------------
==========================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Terry Allen Kramer
- ---------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
- ---------------------------------------------------------------------------
3 SEC USE ONLY
- ---------------------------------------------------------------------------
4 SOURCE OF FUNDS*
Not Applicable
- ---------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(E) [ ]
- ---------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- ---------------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
- ---------------------------------------------------------------------------
7 SOLE VOTING POWER
11,268
- ---------------------------------------------------------------------------
8 SHARED VOTING POWER
0
- ---------------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
11,268
- ---------------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
- ---------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
11,268
- ---------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [ ]
- ---------------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
Less than 0.1%
- ---------------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
IN
===========================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!
SEC 1746 (9-88)<PAGE>
<PAGE>
SCHEDULE 13D
- --------------------- ------------------
CUSIP No. 449695303 Page 7 of 35 Pages
- --------------------- -------------------
==========================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Bruce Allen
- ---------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
- ---------------------------------------------------------------------------
3 SEC USE ONLY
- ---------------------------------------------------------------------------
4 SOURCE OF FUNDS*
Not Applicable
- ---------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(E) [ ]
- ---------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- ---------------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
- ---------------------------------------------------------------------------
7 SOLE VOTING POWER
640,245
- ---------------------------------------------------------------------------
8 SHARED VOTING POWER
0
- ---------------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
640,245
- ---------------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
- ---------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
640,245
- ---------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [ ]
- ---------------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
1.8%
- ---------------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
IN
===========================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!
SEC 1746 (9-88)<PAGE>
<PAGE>
SCHEDULE 13D
- --------------------- ------------------
CUSIP No. 449695303 Page 8 of 35 Pages
- --------------------- -------------------
==========================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Susan K. Allen
- ---------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
- ---------------------------------------------------------------------------
3 SEC USE ONLY
- ---------------------------------------------------------------------------
4 SOURCE OF FUNDS*
Not Applicable
- ---------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(E) [ ]
- ---------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- ---------------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
- ---------------------------------------------------------------------------
7 SOLE VOTING POWER
630,119
- ---------------------------------------------------------------------------
8 SHARED VOTING POWER
0
- ---------------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
630,119
- ---------------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
- ---------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
630,119
- ---------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [ ]
- ---------------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
1.8%
- ---------------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
IN
===========================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!
SEC 1746 (9-88)<PAGE>
<PAGE>
SCHEDULE 13D
- --------------------- ------------------
CUSIP No. 449695303 Page 9 of 35 Pages
- --------------------- -------------------
==========================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Richard M. Crooks, Jr.
- ---------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
- ---------------------------------------------------------------------------
3 SEC USE ONLY
- ---------------------------------------------------------------------------
4 SOURCE OF FUNDS*
Not Applicable
- ---------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(E) [ ]
- ---------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- ---------------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
- ---------------------------------------------------------------------------
7 SOLE VOTING POWER
422,401 Shares (includes 40,000 Common Stock Options)
- ---------------------------------------------------------------------------
8 SHARED VOTING POWER
0
- ---------------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
422,401 Shares (includes 40,000 Common Stock Options)
- ---------------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
- ---------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,121,897 (includes 692,829 shares of the Issuer's Common Stock (the
"Shares") and 6,667 Common Stock Purchase Warrants to purchase 6,667
shares of the Issuer's Common Stock (the "Warrants") owned of record by
Allen & Company Incorporated ("ACI") which may be deemed to be
indirectly owned by Mr. Crooks. Pursuant to an arrangement with ACI,
Mr. Crooks may be deemed to have a pecuniary interest in a portion of
certain securities, including the Issuer's Common Stock owned by ACI.
Consequently, the Shares and the Warrants represent, approximately, the
portion of ACI's holdings of the Issuer's Common Stock from which Mr.
Crooks may realize profits. The Warrants and the Shares assume the
conversion of 6,667 Units. Each unit consists of two shares of Common
Stock and one Common Stock Purchase Warrant.)
- ---------------------------------------------------------------------------
<PAGE>
<PAGE>
SCHEDULE 13D
- --------------------- ------------------
CUSIP No. 449695303 Page 10 of 35 Pages
- --------------------- -------------------
- ---------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [ ]
- ---------------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
3.2%
- ---------------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
IN
===========================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!
SEC 1746 (9-88)<PAGE>
<PAGE>
SCHEDULE 13D
- --------------------- ------------------
CUSIP No. 449695303 Page 11 of 35 Pages
- --------------------- -------------------
==========================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
James W. Quinn
- ---------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
- ---------------------------------------------------------------------------
3 SEC USE ONLY
- ---------------------------------------------------------------------------
4 SOURCE OF FUNDS*
Not Applicable
- ---------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(E) [ ]
- ---------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- ---------------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
- ---------------------------------------------------------------------------
7 SOLE VOTING POWER
500
- ---------------------------------------------------------------------------
8 SHARED VOTING POWER
0
- ---------------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
500
- ---------------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
- ---------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
500
- ---------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [ ]
- ---------------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
Less than 0.1%
- ---------------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
IN
===========================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!
SEC 1746 (9-88)<PAGE>
<PAGE>
SCHEDULE 13D
- --------------------- ------------------
CUSIP No. 449695303 Page 12 of 35 Pages
- --------------------- -------------------
==========================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Eugene Protash
- ---------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
- ---------------------------------------------------------------------------
3 SEC USE ONLY
- ---------------------------------------------------------------------------
4 SOURCE OF FUNDS*
Not Applicable
- ---------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(E) [ ]
- ---------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- ---------------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
- ---------------------------------------------------------------------------
7 SOLE VOTING POWER
800
- ---------------------------------------------------------------------------
8 SHARED VOTING POWER
0
- ---------------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
800
- ---------------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
- ---------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
800
- ---------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [ ]
- ---------------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
Less than 0.1%
- ---------------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
IN
===========================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!
SEC 1746 (9-88)<PAGE>
<PAGE>
SCHEDULE 13D
- --------------------- ------------------
CUSIP No. 449695303 Page 13 of 35 Pages
- --------------------- --------------------
==========================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Robert J. Kurz
- ---------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
- ---------------------------------------------------------------------------
3 SEC USE ONLY
- ---------------------------------------------------------------------------
4 SOURCE OF FUNDS*
Not Applicable
- ---------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(E) [ ]
- ---------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- ---------------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
- ---------------------------------------------------------------------------
7 SOLE VOTING POWER
9,000
- ---------------------------------------------------------------------------
8 SHARED VOTING POWER
0
- ---------------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
9,000
- ---------------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
- ---------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
9,000
- ---------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [ ]
- ---------------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
less than 0.1%
- ---------------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
IN
===========================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!
SEC 1746 (9-88)<PAGE>
<PAGE>
SCHEDULE 13D
- --------------------- ------------------
CUSIP No. 449695303 Page 14 of 35 Pages
- --------------------- -------------------
==========================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Walter T. O'Hara, Jr.
- ---------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
- ---------------------------------------------------------------------------
3 SEC USE ONLY
- ---------------------------------------------------------------------------
4 SOURCE OF FUNDS*
Not Applicable
- ---------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(E) [ ]
- ---------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- ---------------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
- ---------------------------------------------------------------------------
7 SOLE VOTING POWER
15,000
- ---------------------------------------------------------------------------
8 SHARED VOTING POWER
0
- ---------------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
15,000
- ---------------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
- ---------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
15,000
- ---------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [ ]
- ---------------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
less than 0.1%
- ---------------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
IN
===========================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!
SEC 1746 (9-88)<PAGE>
<PAGE>
SCHEDULE 13D
- --------------------- ------------------
CUSIP No. 449695303 Page 15 of 35 Pages
- --------------------- -------------------
==========================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Brian Murphy
- ---------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
- ---------------------------------------------------------------------------
3 SEC USE ONLY
- ---------------------------------------------------------------------------
4 SOURCE OF FUNDS*
Not Applicable
- ---------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(E) [ ]
- ---------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- ---------------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
- ---------------------------------------------------------------------------
7 SOLE VOTING POWER
5,000
- ---------------------------------------------------------------------------
8 SHARED VOTING POWER
0
- ---------------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
5,000
- ---------------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
- ---------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
5,000
- ---------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [ ]
- ---------------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
Less than 0.1%
- ---------------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
IN
===========================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!
SEC 1746 (9-88)<PAGE>
<PAGE>
SCHEDULE 13D
- --------------------- ------------------
CUSIP No. 449695303 Page 16 of 35 Pages
- --------------------- --------------------
==========================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Catherine Greenfield
- ---------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
- ---------------------------------------------------------------------------
3 SEC USE ONLY
- ---------------------------------------------------------------------------
4 SOURCE OF FUNDS*
Not Applicable
- ---------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(E) [ ]
- ---------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- ---------------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
- ---------------------------------------------------------------------------
7 SOLE VOTING POWER
1,400
- ---------------------------------------------------------------------------
8 SHARED VOTING POWER
0
- ---------------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
1,400
- ---------------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
- ---------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,400
- ---------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [ ]
- ---------------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
Less than 0.1%
- ---------------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
IN
===========================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!
SEC 1746 (9-88)<PAGE>
<PAGE>
SCHEDULE 13D
- --------------------- ------------------
CUSIP No. 449695303 Page 17 of 35 Pages
- --------------------- --------------------
==========================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Dennis Warfield
- --------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
- ---------------------------------------------------------------------------
3 SEC USE ONLY
- ---------------------------------------------------------------------------
4 SOURCE OF FUNDS*
Not Applicable
- ---------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(E) [ ]
- ---------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- ---------------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
- ---------------------------------------------------------------------------
7 SOLE VOTING POWER
1,000
- ---------------------------------------------------------------------------
8 SHARED VOTING POWER
0
- ---------------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
1,000
- ---------------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
- ---------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,000
- ---------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [ ]
- ---------------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
Less than 0.1%
- ---------------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
IN
===========================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!
SEC 1746 (9-88)<PAGE>
<PAGE>
SCHEDULE 13D
- --------------------- ------------------
CUSIP No. 449695303 Page 18 of 35 Pages
- --------------------- --------------------
==========================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Mary Cullen
- ---------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
- ---------------------------------------------------------------------------
3 SEC USE ONLY
- ---------------------------------------------------------------------------
4 SOURCE OF FUNDS*
Not Applicable
- ---------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(E) [ ]
- ---------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- ---------------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
- ---------------------------------------------------------------------------
7 SOLE VOTING POWER
44,500
- ---------------------------------------------------------------------------
8 SHARED VOTING POWER
0
- ---------------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
44,500
- ---------------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
- ---------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
44,500
- ---------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [ ]
- ---------------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
0.1%
- ---------------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
IN
===========================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!
SEC 1746 (9-88)<PAGE>
<PAGE> Page 19 of 35 Pages
AMENDMENT NO. 22
TO
SCHEDULE 13D
The Reporting Persons hereby amend their Schedule 13D relating to
the Common Stock, $0.02 per share of Cypress BioScience Incorporation (the
"Issuer") principally to reflect an increase in the ownership position of
Allen & Company Incorporated ("ACI"). However, due to the Issuer's
increase in its number of outstanding shares of Common Stock, ACI's
ownership percentage has, in fact, decreased.
Item 3. Source and Amount of Funds or Other Consideration.
Pursuant to the October 3, 1997 private placement of Common Stock
by the Issuer, ACI purchased 333,333 shares of the Issuer's Common Stock at
$1.50 per share, for an aggregate purchase price of $499,999.50. ACI
purchased such shares with its own funds.
Item 5. Interest in Securities of the Issuer
(a) As of the close of business on October 3, 1997, the
Reporting Persons, by virtue of the language of Rule 13d-3(d)(1)(i), may be
deemed to own beneficially in the aggregate the number and percentage of
the Issuer's Common Stock set forth below. (Based upon information provided
by the Issuer in its Quarterly report on Form 10-Q for the quarter ended
June 30, 1997, the number of shares of Common Stock outstanding is
34,636,067).
<TABLE>
<CAPTION>
=================================================================
Name Shares Percentage
- -----------------------------------------------------------------
<S> <C> <C>
Allen Holding Inc. 0 (1) 0.0%
Allen & Company Incorporated 5,829,698 (2) 16.5%
The Estate of Herbert A. Allen 599,359 1.7%
Irwin H. Kramer 11,268 *
Terry Allen Kramer 11,268 *
Bruce Allen 640,245 1.8%
Susan K. Allen 630,119 1.8%
Richard M. Crooks, Jr. 1,121,897 (3) 3.2%
James W. Quinn 500 *
Eugene Protash 800 *
Robert J. Kurz 9,000 *
Walter T. O'Hara, Jr. 15,000 *
Brian Murphy 5,000 *
Catherine Greenfield 1,400 *
Dennis Warfield 1,000 *
Mary Cullen 44,500 0.1%
_______________
* Less than 0.1%
(1) Excludes shares owned indirectly through Allen & Company Incorporated
("ACI").
<PAGE>
<PAGE> Page 20 of 35 Pages
(2) Consists of 125,000 Units and a total of 228,000 Common Stock Purchase
Warrants (each Unit consists of two shares of Common Stock and one
Common Stock Purchase Warrant). Includes 105,869 shares in a market
maker account.
(3) Including 40,000 Common Stock Options
(c) Transactions effected by the Reporting Person within the past 60
days, other than the purchase described above in Item 3, are listed on
Exhibit B attached hereto.
<PAGE>
<PAGE> Page 21 of 35 Pages
Item 7. Material to be Filed as Exhibits.
Exhibit A: Officers and Directors of Allen Holding Inc. and
Officers and Directors of Allen & Company Incorporated
Exhibit B: Market Maker Transactions.
<PAGE>
<PAGE> Page 22 of 35 Pages
After reasonable inquiry and to the best of our knowledge
and belief, each of the signatories certifies that the
information set forth in this Schedule relating to the respective
signatory is true, complete and correct.
Dated: November 14, 1996
ALLEN HOLDING INC. ALLEN & COMPANY INCORPORATED
By: /s/ Gaetano J. Casillo By: /s/ Gaetano J. Casillo
------------------------- ------------------------
Name: Gaetano J. Casillo Name: Gaetano J. Casillo
Title: Vice President Title: Vice President
/s/ Herbert Allen /s/ Susan K. Wilson
- --------------------------- ---------------------------
The Estate of Herbert Allen Susan K. Wilson
/s/ Irwin Kramer /s/ Richard M. Crooks, Jr.
- --------------------------- ---------------------------
Irwin Kramer Richard M. Crooks, Jr.
/s/ Terry Allen Kramer /s/ James W. Quinn
- --------------------------- ---------------------------
Terry Allen Kramer James W. Quinn
/s/ Bruce Allen /s/ Walter T. O'Hara, Jr.
- --------------------------- ---------------------------
Bruce Allen Walter T. O'Hara, Jr.
/s/ Eugene Protash /s/ Robert J. Kurz
- --------------------------- ---------------------------
Eugene Protash Robert J. Kurz
/s/ Mary Cullen /s/ Dennis Warfield
- --------------------------- ---------------------------
Mary Cullen Dennis Warfield
/s/ Brian Murphy /s/ Catherine Greenfield
- --------------------------- ---------------------------
Brian Murphy Catherine Greenfield
<PAGE>
<PAGE> Page 23 of 35 Pages
</TABLE>
<TABLE>
EXHIBIT A
OFFICERS AND DIRECTORS OF ALLEN & COMPANY INCORPORATED
<S> <C> <C>
Principal Occupation
Business (i.e., Position with
Name xx Address Allen & Company Incorporated)
Herbert A. Allen x President, Managing Director,
Director, Chief Executive Officer
Herbert A. Allen III x Vice President, Director
Grace Allen x Director
Eran S. Ashany x Vice President, Director
Jonathan S. Bean x Vice President
Robert E. Beers x Vice President
Edmund M. Bleich x Vice President
Denise Calvo-Silver x Vice President, Director
Dominick J. Cantalupo x Co-Chief Operations Officer, Vice
President
Marvyn Carton x Director - Emeritus
Gaetano J. Casillo x Chief Compliance Officer,
Vice President
Robert H. Cosgriff x Chief Administrative Officer,
Executive Vice President,
Managing Director, Director
Richard M. Crooks, Jr. x Director
Thalia V. Crooks x Vice President, Director
Mary L. Cullen x Vice President, Secretary,
Director
Orin F. Devereux x Vice President, Director
Howard M. Felson x Assistant Secretary, Vice
President
Anthony J. Ferrante x Treasurer
Richard Fields x Executive Vice President,
Managing Director, Director
<PAGE>
<PAGE> Page 24 of 35 Pages
Principal Occupation
Business (i.e., Position with
Name xx Address Allen & Company Incorporated)
Paul A. Gould x Executive Vice President,
Managing Director, Director
John G. Hall x Vice President - Elect, Director
Daniel P. Harley x Vice President
John H. Josephson x Vice President, Director
Clark R. Keough x Vice President, Director
Donald R. Keough x Chairman of the Board, Director
Dara Khosrowshahi x Vice President, Director
Kaveh A. Khosrowshahi x Vice President, Director
Neal Kopp x Vice President
Irwin H. Kramer x Executive Vice President,
Managing Director, Director
Terry Allen Kramer x Director
Suzanne G. Kucera x Vice President - Elect, Director
Robert J. Kurz x Vice President
William F. Leimkuhler x Assistant Secretary, Vice
President General, Counsel
Jeffrey J. Logan x Vice President
Sharon K. Losee x Vice President
Dan W. Lufkin x Special Advisor to the Board of
Directors
Ellen F. Lynch x Vice President
Robert A. Mackie x Executive Vice President,
Managing Director, Director
James C. Maiden, Jr. x Vice President
Terence A. McCarthy x Co-Chief Operations Officer, Vice
President
Robert C. Miller x Vice President - Elect, Director
Brian J. Murphy x Vice President, Director
Louis J. Mustacchio x Vice President
<PAGE>
<PAGE> Page 25 of 35 Pages
Principal Occupation
Business (i.e., Position with
Name xx Address Allen & Company Incorporated)
Walter T. O'Hara, Jr. x Executive Vice President,
Managing Director, Director
Glenn A. Okun x Vice President, Director
Nancy B. Peretsman x Executive Vice President,
Managing Director, Director
Patrick S. Perry x Vice President, Director
Pamela M. Plager x Vice President, Director
Eugene Protash x Vice President, Assistant
Secretary
James W. Quinn x Chief Financial Officer,
Director, Vice President,
Assistant Secretary
Philip D. Scaturro x Executive Vice President,
Managing Director, Director
John A. Schneider x Executive Vice President,
Managing Director, Director
Enrique F. Senior x Executive Vice President,
Managing Director, Director
Stanley S. Shuman x Executive Vice President,
Managing Director, Director
John M. Simon x Executive Vice President,
Managing Director, Director
Daniel Selmonosky x Vice President, Director
Ian G. Smith x Vice President - Elect
Lauren M. Tyler x Vice President, Director
Dennis J. Warfield x Vice President,Chief Information
Officer
Kim M. Weiland x Vice President - Elect, Director
Edward D. Weinberger x Vice President, Director
Harold M. Wit x Executive Vice President,
Managing Director, Director
</TABLE>
x 711 Fifth Avenue, New York, New
York 10022-3194.
xx All the Executive Officers and
Directors of Allen & Company
Incorporated are U.S. citizens
unless otherwise indicated.
<PAGE>
<PAGE> Page 26 of 35 Pages
<TABLE>
OFFICERS AND DIRECTORS
OF ALLEN HOLDING INC.
<S> <C> <C>
Principal Occupation
Business (i.e., Position with
Name xx Address Allen & Company Incorporated)
Herbert A. Allen x President, Managing Director,
Director, Chief Executive Officer
Herbert A. Allen, III x Vice President, Director
Grace Allen x Director
Eran S. Ashany x Vice President
Jonathan S. Bean x Vice President - Elect
Robert E. Beers x Vice President - Elect
Edmund M. Bleich x Vice President
Denise Calvo-Silver x Vice President, Director
Dominick J. Cantalupo x Co-Chief Operations Officer, Vice
President
Marvyn Carton x Director - Emeritus
Gaetano J. Casillo x Chief Compliance Officer, Vice
President
Robert H. Cosgriff x Chief Administrative Officer,
Executive Vice President,
Managing Director, Director
Richard M. Crooks, Jr. x Director
Thalia V. Crooks x Vice President, Director
Mary L. Cullen x Vice President, Secretary,
Director
Orin F. Devereux x Vice President, Director
Howard M. Felson x Assistant Secretary, Vice
President
Anthony J. Ferrante x Treasurer
Richard L. Fields x Executive Vice President,
Managing Director, Director
Executive Vice President,
Managing Director, Director
<PAGE>
<PAGE> Page 27 of 35 Pages
Principal Occupation
Business (i.e., Position with
Name xx Address Allen & Company Incorporated)
John G. Hall x Vice President - Elect, Director
Daniel P. Harley x Vice President
John H. Josephson x Vice President, Director
Donald R. Keough x Chairman, Director
Clark R. Keough x Vice President, Director
Dara Khosrowshahi x Vice President, Director
Kaveh A. Khosrowshahi x Vice President, Director
Neal Kopp x Vice President
Irwin H. Kramer x Executive Vice President,
Managing Director, Director
Terry Allen Kramer x Director
Suzanne G. Kucera x Vice President - Elect, Director
Robert J. Kurz x Vice President
P. Don Lattimer x Executive Vice President,
Managing Director, Director
William F. Leimkuhler x Assistant Secretary, Vice
President General, Counsel
Jeffrey J. Logan x Vice President
Sharon K. Losee x Vice President
Dan W. Lufkin x Special Advisor to the Board of
Directors
Ellen F. Lynch x Vice President
Robert A. Mackie x Executive Vice President,
Managing Director, Director
James C. Maiden, Jr. x Vice President
Terence C. McCarthy x Co-Chief Operations Officer, Vice
President Vice President - Elect,
Director
Brian J. Murphy x Vice President, Director
Louis J. Mustacchio x Vice President
<PAGE>
<PAGE> Page 28 of 35 Pages
Principal Occupation
Business (i.e., Position with
Name xx Address Allen & Company Incorporated)
Walter T. O'Hara x Executive Vice President,
Managing Director, Director
Glenn A. Okun x Vice President, Director
Nancy B. Peretsman x Executive Vice President,
Managing Director, Director
Patrick S. Perry x Vice President, Director
Pamela M. Plager x Vice President, Director
Eugene Protash x Assistant Secretary, Vice
President
James W. Quinn x Chief Financial Officer, Vice
President, Assistant Secretary,
Director
Philip D. Scaturro x Executive Vice President,
Managing Director, Director
John A. Schneider x Executive Vice President,
Managing Director, Director
Daniel Selmonosky x Vice President, Director
Enrique F. Senior x Executive Vice President,
Managing Director, Director
Stanley S. Shuman x Executive Vice President,
Managing Director, Director
John M. Simon x Executive Vice President,
Managing Director, Director
Ian G. Smith x Vice President - Elect
Lauren M. Tyler x Vice President, Director
Dennis J. Warfield x Vice President, Chief Information
Officer
Kim M. Weiland x Vice President, Director
Edward D. Weinberger x Vice President, Director
Executive Vice President,
Managing Director, Director
</TABLE>
x 711 Fifth Avenue, New York, New
York 10022-3194.
xx All the Executive Officers and
Directors of Allen Holding, Inc.
are U.S. citizens unless
otherwise indicated.
<PAGE>
<PAGE> Page 29 of 35 pages
ALLEN TRADE DATE HISTORY REPORT
PAGE : 1
DATE : 11-05-1997
T/D S/D B/S CXL BL SEC# CUSIP# SYM QUANTITY PRICE
- -------- -------- - --- -- ------- ------------ -------- -------- ---------
09/05/97 09/10/97 B 6D C000217 232674101000 CYPB 900 1.71875
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
09/05/97 09/10/97 S 6D C000217 232674101000 CYPB 2500 1.75
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
09/08/97 09/11/97 B 6D C000217 232674101000 CYPB 2000 1.6875
CYPRESS BIOSCIENCES INC
SNET
WE MAKE A MKT IN THIS SECURI
09/08/97 09/11/97 B 6D C000217 232674101000 CYPB 2000 1.6875
CYPRESS BIOSCIENCES INC
SNET
WE MAKE A MKT IN THIS SECURI
09/18/97 09/23/97 B 6N C000217 232674101000 CYPB 10000 2
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
09/18/97 09/23/97 S 6D C000217 232674101000 CYPB 2000 2.0625
CYPRESS BIOSCIENCES INC
SNET
WE MAKE A MKT IN THIS SECURI
09/22/97 09/25/97 S 6D C000217 232674101000 CYPB 3000 2
CYPRESS BIOSCIENCES INC
INCA
WE MAKE A MKT IN THIS SECURI
<PAGE>
<PAGE> Page 30 of 35 pages
ALLEN TRADE DATE HISTORY REPORT
PAGE : 2
DATE : 11-05-1997
T/D S/D B/S CXL BL SEC# CUSIP# SYM QUANTITY PRICE
- -------- -------- - --- -- ------- ------------ -------- -------- ---------
09/26/97 10/01/97 B 6D C000217 232674101000 CYPB 5000 1.9375
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
10/01/97 10/06/97 B 6D C000217 232674101000 CYPB 4000 1.90625
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
10/02/97 10/07/97 B 6D C000217 232674101000 CYPB 5324 1.875
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
10/03/97 10/08/97 B 6D C000217 232674101000 CYPB 1500 1.8125
CYPRESS BIOSCIENCES INC
SNET
WE MAKE A MKT IN THIS SECURI
10/03/97 10/08/97 B 6D C000217 232674101000 CYPB 1500 1.8125
CYPRESS BIOSCIENCES INC
SNET
WE MAKE A MKT IN THIS SECURI
10/03/97 10/08/97 S 6D C000217 232674101000 CYPB 1000 1.9375
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
10/06/97 10/09/97 B 6N C000217 232674101000 CYPB 10000 1.8125
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
<PAGE>
<PAGE> Page 31 of 35 pages
ALLEN TRADE DATE HISTORY REPORT
PAGE : 3
DATE : 11-05-1997
T/D S/D B/S CXL BL SEC# CUSIP# SYM QUANTITY PRICE
- ------ -------- - --- -- ------- ------------ -------- -------- ----------
10/07/97 10/10/97 B 6D C000217 232674101000 CYPB 1000 1.75
CYPRESS BIOSCIENCES INC
SNET
WE MAKE A MKT IN THIS SECURI
10/08/97 10/14/97 B 6D C000217 232674101000 CYPB 800 1.71875
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
10/09/97 10/15/97 S 6D C000217 232674101000 CYPB 2000 1.875
CYPRESS BIOSCIENCES INC
INCA
WE MAKE A MKT IN THIS SECURI
10/10/97 10/16/97 B 6D C000217 232674101000 CYPB 300 1.875
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
10/15/97 10/20/97 S 6D C000217 232674101000 CYPB 1000 1.875
CYPRESS BIOSCIENCES INC
INCA
WE MAKE A MKT IN THIS SECURI
10/15/97 10/20/97 S 6D C000217 232674101000 CYPB 2000 1.875
CYPRESS BIOSCIENCES INC
INCA
WE MAKE A MKT IN THIS SECURI
10/16/97 10/21/97 B 6D C000217 232674101000 CYPB 1000 1.75
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
<PAGE>
<PAGE> Page 32 of 35 pages
ALLEN TRADE DATE HISTORY REPORT
PAGE : 4
DATE : 11-05-1997
T/D S/D B/S CXL BL SEC# CUSIP# SYM QUANTITY PRICE
-------- - --- -- ------- ------------ -------- -------- ----------
10/16/97 10/21/97 B 6D C000217 232674101000 CYPB 5000 1.78125
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
10/16/97 10/21/97 S 6D C000217 232674101000 CYPB 6000 1.8125
CYPRESS BIOSCIENCES INC
INCA
WE MAKE A MKT IN THIS SECURI
10/16/97 10/21/97 S 6D C000217 232674101000 CYPB 9000 1.8125
CYPRESS BIOSCIENCES INC
INCA
WE MAKE A MKT IN THIS SECURI
10/17/97 10/22/97 S 6D C000217 232674101000 CYPB 1000 1.8125
CYPRESS BIOSCIENCES INC
INCA
WE MAKE A MKT IN THIS SECURI
10/17/97 10/22/97 S 6D C000217 232674101000 CYPB 3000 1.8125
CYPRESS BIOSCIENCES INC
INCA
WE MAKE A MKT IN THIS SECURI
10/20/97 10/23/97 S 6D C000217 232674101000 CYPB 1000 1.84375
CYPRESS BIOSCIENCES INC
INCA
WE MAKE A MKT IN THIS SECURI
10/20/97 10/23/97 S 6D C000217 232674101000 CYPB 1000 1.84375
CYPRESS BIOSCIENCES INC
INCA
WE MAKE A MKT IN THIS SECURI
<PAGE>
<PAGE> Page 33 of 35 pages
ALLEN TRADE DATE HISTORY REPORT
PAGE : 5
DATE : 11-05-1997
T/D S/D B/S CXL BL SEC# CUSIP# SYM QUANTITY PRICE
- ------- - --- -- ------- ------------ -------- -------- ----------
10/20/97 10/23/97 S 6D C000217 232674101000 CYPB 1000 1.875
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
10/20/97 10/23/97 S 6D C000217 232674101000 CYPB 4000 1.84375
CYPRESS BIOSCIENCES INC
INCA
WE MAKE A MKT IN THIS SECURI
10/20/97 10/23/97 S 6D C000217 232674101000 CYPB 4000 1.84375
CYPRESS BIOSCIENCES INC
INCA
WE MAKE A MKT IN THIS SECURI
10/21/97 10/24/97 S 6D C000217 232674101000 CYPB 1000 1.875
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
10/27/97 10/30/97 B 6D C000217 232674101000 CYPB 9000 1.65625
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
10/28/97 10/31/97 B 6D C000217 232674101000 CYPB 800 1.5
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
10/28/97 10/31/97 B 6D C000217 232674101000 CYPB 1000 1.5
CYPRESS BIOSCIENCES INC
SNET
WE MAKE A MKT IN THIS SECURI
<PAGE>
<PAGE> Page 34 of 35 Pages
ALLEN TRADE DATE HISTORY REPORT
PAGE : 6
DATE : 11-05-1997
T/D S/D B/S CXL BL SEC# CUSIP# SYM QUANTITY PRICE
-------- - --- -- ------- ------------ -------- -------- ----------
10/28/97 10/31/97 B 6D C000217 232674101000 CYPB 1000 1.5
CYPRESS BIOSCIENCES INC
SNET
WE MAKE A MKT IN THIS SECURI
10/28/97 10/31/97 B 6D C000217 232674101000 CYPB 1000 1.625
CYPRESS BIOSCIENCES INC
SNET
WE MAKE A MKT IN THIS SECURI
10/28/97 10/31/97 B 6D C000217 232674101000 CYPB 25000 1.53125
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
10/28/97 10/31/97 B 6D C000217 232674101000 CYPB 25000 1.53125
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
10/28/97 10/31/97 S 6D C000217 232674101000 CYPB 5000 1.53125
CYPRESS BIOSCIENCES INC
SNET
WE MAKE A MKT IN THIS SECURI
10/29/97 11/03/97 S 6D C000217 232674101000 CYPB 10000 1.59375
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
10/30/97 11/04/97 B 7N C000217 232674101000 CYPB 100000 1.5
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
<PAGE>
<PAGE> Page 35 of 35 pages
ALLEN TRADE DATE HISTORY REPORT
PAGE : 7
DATE : 11-05-1997
T/D S/D B/S CXL BL SEC# CUSIP# SYM QUANTITY PRICE
- ------- - --- -- ------- ------------ -------- -------- ----------
10/30/97 11/04/97 S 7N C000217 232674101000 CYPB 100000 1.5
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
10/31/97 11/05/97 S 6D C000217 232674101000 CYPB 1134 1.65625
CYPRESS BIOSCIENCES INC
INCA
WE MAKE A MKT IN THIS SECURI
10/31/97 11/05/97 S 6D C000217 232674101000 CYPB 3490 1.71875
CYPRESS BIOSCIENCES INC
WE MAKE A MKT IN THIS SECURITY
11/03/97 11/06/97 S 6D C000217 232674101000 CYPB 2300 1.78125
CYPRESS BIOSCIENCES INC
INCA
WE MAKE A MKT IN THIS SECURI
11/03/97 11/06/97 S 6D C000217 232674101000 CYPB 4000 1.78125
CYPRESS BIOSCIENCES INC
INCA
WE MAKE A MKT IN THIS SECURI
11/03/97 11/06/97 S 6D C000217 232674101000 CYPB 4000 1.78125
CYPRESS BIOSCIENCES INC
INCA
WE MAKE A MKT IN THIS SECURI
11/04/97 11/07/97 S 6D C000217 232674101000 CYPB 2000 1.75
CYPRESS BIOSCIENCES INC
INCA
WE MAKE A MKT IN THIS SECURI
106955
