<PAGE>
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13D
Under the Securities Exchange Act of 1934
(Amendment No. 24)
CYPRESS BIOSCIENCE INCORPORATED
(Name of Issuer)
Common Stock $0.02 Par Value
(Title of Class of Securities)
449695303
(CUSIP Number)
Allen & Company Incorporated
711 Fifth Avenue, New York, New York 10022, (212) 832-8000
(Name, Address and Telephone Number of Person Authorized
to Receive Notices and Communications)
February 18, 2000
(Date of Event which Requires Filing of this Statement)
If the filing person has previously filed a statement on Schedule 13G to report
the acquisition which is the subject of this Schedule 13D, and is filing this
schedule because of Section 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check
the following box [ ].
The information required on the remainder of this cover page shall not be
deemed to be "filed" for the purposes of Section 18 of the Securities Exchange
Act of 1934 ("Act") or otherwise subject to the liabilities of that
section of the Act but shall be subject to all other provisions of the Act
(however, see the Notes).
Page 1
============================================================================
<PAGE>
SCHEDULE 13D
--------------------- ---------------
CUSIP No. 449695303 Page 2
--------------------- ---------------
======================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
ALLEN HOLDING INC.
----------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [
] (b) [X]
---------------------------------------------------------------------
3 SEC USE ONLY
---------------------------------------------------------------------
4 SOURCE OF FUNDS*
Not Applicable
---------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(E) [ ]
----------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
---------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
----------------------------------------------------------------------
7 SOLE VOTING POWER
0
----------------------------------------------------------------------
8 SHARED VOTING POWER
0
----------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
0
----------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
----------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
0
----------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [X]
Excluding 1,150,981 shares
----------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
0.0%
----------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
HC====================================================================
SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!
<PAGE>
SCHEDULE 13D
--------------------- ---------------
CUSIP No. 449695303 Page 3
--------------------- ---------------
======================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
ALLEN & COMPANY INCORPORATED
---------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
----------------------------------------------------------------------
3 SEC USE ONLY
----------------------------------------------------------------------
4 SOURCE OF FUNDS*
WC
----------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(e) [ ]
----------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
New York
---------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
---------------------------------------------------------------------
7 SOLE VOTING POWER
1,150,981 Shares
----------------------------------------------------------------------
8 SHARED VOTING POWER
0
---------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
1,150,981 Shares
----------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
----------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,150,981 Shares
----------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [X]
----------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 2.4%
----------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
BC,CO
======================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!
<PAGE>
SCHEDULE 13D
--------------------- -----------------
CUSIP No. 449695303 Page 4
--------------------- -----------------
======================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Herbert A. Allen
----------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
----------------------------------------------------------------------
3 SEC USE ONLY
----------------------------------------------------------------------
4 SOURCE OF FUNDS*
Not Applicable
----------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(E) [ ]
----------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
----------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
----------------------------------------------------------------------
7 SOLE VOTING POWER
504,824
----------------------------------------------------------------------
8 SHARED VOTING POWER
0
----------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
504,824
----------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
----------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
504,824
----------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [ ]
----------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
1.0%
----------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
IN
======================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!
SEC 1746 (9-88)
<PAGE>
SCHEDULE 13D
--------------------- ------------------
CUSIP No. 449695303 Page 5
--------------------- ------------------
======================================================================
1 NAME OF REPORTING PERSON -
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Susan K. Allen
----------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [X]
----------------------------------------------------------------------
3 SEC USE ONLY
----------------------------------------------------------------------
4 SOURCE OF FUNDS*
Not Applicable
----------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) or 2(E) [ ]
----------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
----------------------------------------------------------------------
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
----------------------------------------------------------------------
7 SOLE VOTING POWER
847,775
----------------------------------------------------------------------
8 SHARED VOTING POWER
0
----------------------------------------------------------------------
9 SOLE DISPOSITIVE POWER
847,775
----------------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
0
----------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
847,775
----------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES* [ ]
----------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
1.8%
----------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
IN
=====================================================================
*SEE INSTRUCTIONS BELOW BEFORE FILLING OUT!
SEC 1746 (9-88)
<PAGE> Page 6
AMENDMENT NO. 24
TO
SCHEDULE 13D
The Reporting Persons hereby amend their Schedule 13D relating to the
Common Stock, $0.02 per share of Cypress BioScience Incorporation (the "Issuer")
principally to reflect the sale of shares of the Issuers Common Stock by Allen
& Company Incorporated ("ACI") Issuers Common Stock. In this Amendment, the
Reporting Persons have omitted certain formerly reporting persons for one of the
following reasons: (i) they no longer own any shares of Common Stock or (ii)
they own a de minimus amount of Common Stock. The Reporting Persons have also
omitted trades made in ACIs capacity as a market maker.
Item 5. Interest in Securities of the Issuer
(a) As of the close of business on March 31, 2000, the Reporting Persons,
by virtue of the language of Rule 13d-3(d)(1)(i), may be deemed to own
beneficially in the aggregate the number and percentage of the Issuer's Common
Stock set forth below (based upon information provided by the Issuer in its
Annual report on Form 10-Q, which reports that the number of shares of Common
Stock outstanding, as of November 1, 1999 is 46,163,385).
<TABLE>
<CAPTION>
=================================================================
Name Shares Percentage
- -----------------------------------------------------------------
<S> <C> <C>
Allen Holding Inc. 0 (1) 0.0%
Allen & Company Incorporated 1,150,981 (2) 2.4%
Herbert A. Allen 504,824 1.0%
Susan K. Allen 847,775 1.8%
</TABLE>
_____________
(1) Excludes shares owned indirectly through Allen & Company Incorporated
("ACI"). Also, excludes certain shares owned by officers and directors of Allen
Holding Inc.
(2) Excludes shares in ACIs market making accounts. Excludes certain
shares owned by officers and directors of ACI.
(c) No transactions were effected by the Reporting Persons within the past
60 days, other than the sales described below and trades effected by ACI in its
capacity as a market maker.
<PAGE> Page 7
<TABLE>
<CAPTION>
Trades Effected by Allen & Company Incorporated
===============================================================================
Price Per Number of Buy (B) or
Trade Date Share ($) Shares Sell (S)
- -------------------------------------------------------------------------------
<S> <C> <C> <C>
2/18/00 4.080 1,508,817 S
- -------------------------------------------------------------------------------
2/22/00 4.650 630,000 S
- -------------------------------------------------------------------------------
3/3/00 4.557 257,244 S
- -------------------------------------------------------------------------------
3/6/00 4.611 171,496 S
- -------------------------------------------------------------------------------
3/7/00 4.949 757,440 S
- -------------------------------------------------------------------------------
===============================================================================
</TABLE>
<TABLE>
<CAPTION> Trades Effected by Herbert A. Allen
================================================================================
Price Per Number of Buy (B) or
Trade Date Share ($) Shares Sell (S)
- --------------------------------------------------------------------------------
<S> <C> <C> <C>
3/3/00 4.500 54,888 S
- --------------------------------------------------------------------------------
3/6/00 4.531 37,212 S
- --------------------------------------------------------------------------------
3/7/00 4.857 156,718 S
- --------------------------------------------------------------------------------
3/8/00 6.2969 63,024 S
- --------------------------------------------------------------------------------
3/9/00 6.3750 31,511 S
- --------------------------------------------------------------------------------
================================================================================
</TABLE>
<PAGE> Page 8
Trades Effected by Susan K. Allen
<TABLE>
<CAPTION>
========================================================================
Price Per Number of Buy (B) or
Trade Date Share ($) Shares Sell (S)
- ------------------------------------------------------------------------
<S> <C> <C> <C>
3/3/00 4.625 92,048 S
- ------------------------------------------------------------------------
3/6/00 4.6875 62,405 S
- ------------------------------------------------------------------------
3/7/00 4.75 267,233 S
- ------------------------------------------------------------------------
3/8/00 6.2969 104,896 S
- ------------------------------------------------------------------------
3/9/00 6.3750 52,448 S
- ------------------------------------------------------------------------
========================================================================
</TABLE>
<PAGE> Page 9
After reasonable inquiry and to the best of our knowledge and belief, each
of the signatories certifies that the information set forth in this Schedule
relating to the respective signatory is true, complete and correct.
Dated: March 31, 2000
ALLEN HOLDING INC. ALLEN & COMPANY INCORPORATED
By: /s/ Gaetano J.Casillo By: /s/ Gaetano J.Casillo
---------------------- --------------------------
Name: Gaetano J. Casillo Name: Gaetano J. Casillo
Title: Vice President Title: Vice President
271754
