SYNBIOTICS CORP
8-K/A, 1997-09-22
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
Previous: S&T BANCORP INC, 8-K, 1997-09-22
Next: DAIRY MART CONVENIENCE STORES INC, 10-Q, 1997-09-22



<PAGE>
 
===============================================================================


                       SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C.  20549

                              ------------------

                                   FORM 8-K/A
                                Amendment No. 1

                 Current Report Pursuant to Section 13 or 15(d)
                     of The Securities Exchange Act of 1934

        Date of Report (Date of earliest event reported):  July 9, 1997


                             SYNBIOTICS CORPORATION
             (Exact name of registrant as specified in its charter)

                         Commission file number 0-11303


             California                               95-3737816
    (State or other jurisdiction                   (I.R.S. Employer
          of incorporation)                       Identification No.) 
                          
                                                  

         11011 Via Frontera                       
        San Diego, California                           92127   
 (Address of principal executive offices)             (Zip Code) 


      Registrant's telephone number, including area code:  (619) 451-3771


===============================================================================
<PAGE>
 
                          AMENDMENT TO CURRENT REPORT

The Registrant's Current Report on Form 8-K, filed on July 24, 1997 to report
the Registrant's acquisition on July 9, 1997 of the veterinary diagnostic
business of Rhone Merieux S.A.S. is amended to provide financial statements, pro
forma financial information and additional exhibits required by Item 7 of the
report.  There are no other changes to the report as filed.

Item 7.  Financial Statements and Exhibits
         ---------------------------------
<TABLE> 
    <C>  <S>                                                           <C> 
     a)  Financial statements of business acquired:
         ------------------------------------------

         Report of Independent Accountants                              2

         Statement of Assets as of December 31, 1996                   10

         Statement of Revenues and Direct Operating Expenses 
         for the years ended December 31, 1995 and 1996                11

         Notes to Statement of Assets and Statement of Revenues 
         and Direct Operating Expenses                                 12

         Statement of Assets (Unaudited) as of June 30, 1997           13

         Statement of Revenues and Direct Operating Expenses 
         (Unaudited) for the six months ended June 30, 1997            14

         Notes to Unaudited Statement of Assets and Unaudited 
         Statement of Revenues and Direct Operating Expenses           15

</TABLE> 


                                      -1-

<PAGE>
 
Madame Dominique TAKIZAWA
Corporate VP Finance
RHONE-MERIEUX SA
29, avenue Tony Garnier
69007 - LYON


                      RHONE-MERIEUX SA DIAGNOSTIC BUSINESS
                             SPECIAL AUDIT REPORT

1.   We have audited, in accordance with generally accepted auditing standards,
     the statutory financial statements of Rhone-Merieux SA for the year ended
     December 31, 1995 and have issued our report hereon dated February 5, 1996.
     We have audited the financial statements of Rhone-Merieux SA for the year
     ended December 31, 1996, prepared for the purpose of the Rhone-Poulenc
     consolidation for the year then ended, but have not yet issued our report
     on the Rhone-Merieux SA statutory accounts for this year ended December 31,
     1996.  We also have audited the revenues and direct costs of the Rhone-
     Merieux SA diagnostic business for the years ended December 31, 1996 and
     1995 and its fixed assets and inventories as of December 31, 1996,
     presented on the attached schedules.  These schedules are the
     responsibility of Rhone-Merieux SA's management.  Our responsibility is to
     express an opinion on the Rhone-Merieux SA diagnostic business' revenues,
     direct costs, fixed assets and inventories, based on our audit procedures.

2.   These audit procedures were conducted in accordance with generally accepted
     auditing standards.  Those standards require that we plan and perform the
     audit to obtain reasonable assurance whether revenues, direct costs,
     together with fixed assets and inventories, are free of material
     misstatements.  These audit procedures include examining, on a test basis,
     evidence supporting the amounts and also assessing the accounting
     principles used and significant estimates made by management.  We believe
     that our audit procedures provide a reasonable basis for our opinion.

3.   In our opinion, the attached schedules present fairly, in all material
     respects, the Rhone-Merieux SA diagnostic business revenues and direct
     costs for the years ended December 31, 1996 and 1995, and its fixed assets
     and inventories as of December 31, 1996.

4.   At your request, we also have reviewed:

     i)  The allocation of fixed costs, selling and other overheads and research
     and development costs related to the Rhone-Merieux SA diagnostic business
     for the years ended December 31, 1996 and 1995, and presented on the
     attached schedules.

     ii)  Accounts receivable and payable related to the diagnostic business as
     of December 31, 1996.

5.   Our review was made solely to assess the reasonableness of the amounts
     concerned and of the method adopted for allocating fixed costs and non
     direct costs to the diagnostic business and for estimating accounts
     receivable and payable.  It does not constitute an audit conducted in
     accordance with generally accepted auditing standards.  Our procedures and
     findings are as follows:

     i)  Fixed costs (factory overheads)

     We made sure that only fixed costs relating to manufacturing sections
     concerned by the diagnostic business were allocated to this activity.
     These costs have been allocated proportionally to the added value of the
     diagnostic business compared to the whole Rhone-Merieux SA biology added
     value.  In particular, we have 

                                      -2-
<PAGE>
 
     made sure that the fixed costs allocated were not affected by the
     pharmaceuticals (Toulouse) and Frontline activities. We reperformed some
     calculations on a test basis and did not notice any significant exceptions
     or errors.

     ii)  Selling overheads

     We made sure that all costs specific to the diagnostic business were
     allocated directly to this business line.  They correspond to technical
     assistance, marketing, and advertising expenses.  Other costs such as
     salesmen, distribution expenses, administrative expenses, receivables
     depreciation costs, fixed assets depreciation were allocated proportionally
     to the diagnostic business revenues compared to the total Rhone-Merieux SA
     revenues.  We reperformed some calculations on a test basis and did not
     notice any significant errors.

     iii)  Other overheads

     These costs have been allocated proportionally to the added value of the
     diagnostic business compared to the whole Rhone-Merieux SA biology added
     value.  Since this diagnostic business has never been operated as a
     separate operational or legal entity, no better approach could be
     considered.

     iv)  Research and development costs

     Costs specific to the diagnostic business research and development have
     been identified and amount to FF'OOO 5,835 and FF'OOO 6,145 for years 1996
     and 1995, respectively.  We examined documentation supporting this direct
     allocation.  Other R&D costs, FF'OOO 1,068 and FF'OOO 1,154 for years 1996
     and 1995 respectively, have been allocated proportionally to the number of
     the R&D employees pertaining to the diagnostic business.  We reviewed the
     method followed and reperformed some calculation on a test basis and did
     not notice any significant errors or irregularities.

     v) Accounts receivable and payable

     Rhone-Merieux SA does not record receivables and payables related to the
     diagnostic business separately.  Thus, the corresponding amounts as of
     December 31, 1996 included in the attached schedules have been estimated
     based on receivable turnover ratios and payable purchase ratios.  The
     amounts determined thanks to that method are rough estimates and should
     only be regarded as such.

6.   Because the above procedure on fixed and non-direct costs and on accounts
     receivable and payable do not constitute an audit conducted in accordance
     with generally accepted auditing standards, we do not express an opinion on
     the accounts or items referred to above.

7.   In connection with the procedures referred to above, except as indicated in
     paragraph 8 hereafter, no matters came to our attention that caused us to
     believe the specified fixed costs or non-direct costs should be adjusted.

8.   The Rhone-Merieux SA diagnostic business has never been operated as a
     separate operational or legal entity.  Thus, we were unable to ascertain
     that the figures included in the attached schedules include all costs, and
     only those costs, necessary for operating this business as a stand alone.
     Moreover the method used for allocating some non-direct costs,
     proportionally to the diagnostic business added value or number of
     employees, necessarily implies that those costs are affected by the global
     activity level of Rhone-Merieux SA and thus might fluctuate depending on
     the degree of absorption of the Rhone-Merieux SA total fixed costs and non-
     direct costs.  These are the limits of the method adopted, but in the
     circumstances, there was no better way of allocating these categories of
     costs.

                                      -3-
<PAGE>
 
9.   Paragraphs 5 to 8 hereabove relate only to the accounts and items specified
     above (paragraph 4) and do not extend to any financial statement of Rhone-
     Merieux SA taken as a whole.


Lyon, February 14, 1997



Coopers & Lybrand Audit
Bernard R. Rascle
Partner

                                      -4-
<PAGE>
 
                                                                      Schedule 1
                                                                      ----------


                     RHONE-MERIEUX SA DIAGNOSTIC BUSINESS

                               OPERATING RESULTS
                               -----------------
                For the years ended December 31, 1996 and 1995
                ----------------------------------------------


<TABLE>
<CAPTION>
 
           (in French francs Thousands)                          1996                         1995
<S>                                                   <C>                          <C>
 
Revenues                                                                 58,514                       59,844
 
Direct Selling expenses                                                  (1,355)                      (1,415)
 
Direct costs of sales                                                   (18,921)                     (20,842)
 
Royalties                                                                  (786)                        (318)
 
Gross margin after direct costs                                          37,452                       37,269
 
Reviewed but non-audited                               Reviewed but non-audited     Reviewed but non-audited
 
Fixed costs (1)                                                          (4,060)                      (4,734)
 
Gross margin                                                             33,392                       32,535
 
Selling overheads (2)                                                   (14,289)                     (14,122)
 
Other overheads (1)                                                      (4,701)                      (5,512)
 
Research and development costs (3)                                       (6,903)                      (7,299)
Operating profit                                                          7,499                        5,602
- ------------------------------------------------------------------------------------------------------------
</TABLE>

(1)  Part of these costs has been allocated proportionally to the added value of
     the diagnostic business compared to the whole Rhone-Merieux SA biological
     activity added value.

(2)  Allocated proportionally to the net sales of the diagnostic business
     compared to the total net sales of Rhone-Merieux SA.

(3)  Part of these costs has been allocated proportionally to the number of the
     R&D employees pertaining to the diagnostic business compared to the total
     number of employees working in the Rhone-Merieux SA R&D department.

                                      -5-
<PAGE>
 
                                                                      Schedule 2
                                                                      ----------


                      RHONE-MERIEUX SA DIAGNOSTIC BUSINESS


            FIXED ASSETS AND SOME SHORT TERM ASSETS AND LIABILITIES
            -------------------------------------------------------
                                        
                            As of December 31, 1996
                            -----------------------
<TABLE>
<CAPTION>
 
 
                                                     (in French francs Thousand)
<S>                                                         <C>
 
* Fixed assets
 
     Gross value :                                               6,280
     Depreciation :                                              5,273
                                                                 -----
          Net book value:                                        1,007
 

* Inventories

     Net book value:                                            14,964


* Accounts receivable (non-audited)

     Accounts receivable as at December 31, 1996 :               8,811


* Accounts payable (non-audited)

     Accounts payable as at December 31, 1996:                   2,284
</TABLE> 

                                      -6-
<PAGE>
 
                                                                      Schedule 3
                                                                      ----------


                      RHONE MERIEUX SA DIAGNOSTIC BUSINESS

                               OPERATING RESULTS
                               -----------------
                                        
                      For the year ended December 31, 1996
                      ------------------------------------
                                        
                   BREAK OUT OF EXPENSES AND REVENUES BETWEEN
                   ------------------------------------------
                              DIRECT AND INDIRECT
                              -------------------
<TABLE>
<CAPTION>
 
 (in French francs thousands)       Specific to the RM           Allocated to the RM                  Total
                                    diagnostic business          diagnostic business
<S>                              <C>                         <C>                                  <C>
 
Net sales Trade                          58,514                                                         58,514
 
Direct selling expenses                                               1,355                              1,355
 
Raw materials                            14,781                                                         14,781
Depreciation                                322                                                            322
Added value                               3,818                                                          3,818
                                         ------                                                         ------
Direct cost of sales                     18,921                                                         18,921
 
Royalties                                   786                                                            786
 
Gross margin on direct costs             38,807                      (1,355)                            37,452
 
                                                             Reviewed but non-audited       Reviewed but non-audited
 
Fixed costs (factory                        890                       3,170 (1)                          4,060
 overheads)
 
Gross margin                             37,917                      (4,525)                            33,392
 
Selling overheads                         5,962                       8,327 (2)                         14,289
 
Other overheads                               -                       4,701 (1)                          4,701
 
R & D                                     5,835                       1,068 (3)                          6,903
Operating profit                         26,120                     (18,621)                             7,499
- ---------------------------------------------------------------------------------------------------------------------
</TABLE>

(1)  Allocated proportionally to the added value of the diagnostic business
     compared to the whole Rhone-Merieux SA biological activity added value.

(2)  Allocated proportionally to the net sales of the diagnostic business
     compared to the total net sales of Rhone-Merieux SA.

(3)  Allocated proportionally to the number of the R&D employees of the
     diagnostic business compared to the total number of employees in the Rhone-
     Merieux SA R&D department.

                                      -7-
<PAGE>
 
                                                                      Schedule 4



                      RHONE-MERIEUX SA DIAGNOSTIC BUSINESS

                               OPERATING RESULTS
                               -----------------
                                        
                      For the year ended December 31, 1996
                      ------------------------------------
                                        
              BREAK OUT OF SPECIFIC EXPENSES AND REVENUES BETWEEN
              ---------------------------------------------------
                       RHONE-MERIEUX SA AND SUBSIDIARIES
                       ---------------------------------


<TABLE>
<CAPTION>
 
 (in French francs thousands)                       RM SA                 RM Subsidiaries                   Total
<S>                                             <C>                       <C>                          <C>
 
Net sales trade                                     24,783                      33,731                      58,514
 
Raw materials                                        4,373                      10,408                      14,781
Depreciation                                           261                          61                         322
Added value                                          3,061                         757                       3,818
                                                    ------                      ------                      ------
Direct cost of sales                                 7,695                      11,226                      18,921
 
Royalties                                              786                           -                         786
 
Gross margin on direct costs                        16,302                      22,505                      38,807
 
Fixed costs (factory                                   890                           -                         890
 overheads)
 
Gross margin                                        15,412                      22,505                      37,917
 
Selling overheads (schedule 5)                       4,362                       1,600                       5,962
 
Other overheads                                          -                           -                           -
 
R&D (schedule 5)                                     5,835                           -                       5,835
Operating profit                                     5,215                      20,905                      26,120
- ------------------------------------------------------------------------------------------------------------------
</TABLE>

                                      -8-
<PAGE>
 
                                                                      Schedule 5
                                                                      ----------


                      RHONE-MERIEUX SA DIAGNOSTIC BUSINESS

                               OPERATING RESULTS
                               -----------------
                                        
                      For the year ended December 31, 1996
                      ------------------------------------
                                        
                       ANALYSIS OF SELLING OVERHEADS AND
                       ---------------------------------
                                        
                         RESEARCH AND DEVELOPMENT COST
                         -----------------------------



<TABLE>
<CAPTION>
 
           (in French francs Thousands)                 Selling overheads          Research & Development
<S>                                                    <C>                         <C>
 
Wages and salaries                                                  2,776                           2,430
 
Travel expenses                                                       646                             196
 
Advertising expenses                                                  279                               -
  
R&D services rendered by other Rhone-Merieux SA                         -                           2,376
 departments
 
Other                                                                 661                             833
Total (as per schedule 4)                                           4,362                           5,835
- ------------------------------------------------------------------------------------------------------------
</TABLE>

                                      -9-
<PAGE>
 
Rhone-Merieux SA Diagnostic Business

Statement of Assets
- --------------------------------------------------------------------------------
<TABLE> 
<CAPTION> 

 
                                                                  December 31,
                                                                      1996
                                                                      ----
<S>                                                               <C> 
Inventories                                                        $2,885,000
Property, plant and equipment, net                                    194,000
                                                                   ----------

  Total assets                                                     $3,079,000
                                                                   ==========
</TABLE> 

                See accompanying notes to financial statements.

                                      -10-
<PAGE>
 
Rhone-Merieux SA Diagnostic Business

Statement of Revenues and Direct Operating Expenses
- --------------------------------------------------------------------------------

 
 
<TABLE>                                
<CAPTION> 
                                                            Year Ended December 31,
                                                          --------------------------
                                                             1996           1995
                                                             ----           ----
<S>                                                       <C>            <C> 
Revenues                                                  $11,735,000    $11,729,000
 
Direct operating expenses:
  Cost of sales                                             5,015,000      4,606,000
  Research and development                                  1,431,000      1,384,000
  Selling and marketing                                     3,109,000      3,293,000
  General and administrative                                1,081,000        942,000
                                                          -----------    -----------
                    
                                                           10,636,000     10,225,000
                                                          -----------    -----------
 
Excess of revenues over direct operating expenses         $ 1,099,000    $ 1,504,000
                                                          ===========    ===========
</TABLE> 

                See accompanying notes to financial statements.

                                      -11-
<PAGE>
 
Rhone-Merieux SA Diagnostic Business

Notes to Statement of Assets and Statement of Revenues and Direct Operating 
- ---------------------------------------------------------------------------
Expenses
- --------

Note 1 - Business and Asset Purchase Agreement:

The Rhone-Merieux SA diagnostic business (the "Business") is a veterinary
diagnostic product line which is manufactured (however, certain small animal
diagnostic products are manufactured under contract by a third party), sold and
distributed by Rhone Merieux S.A.S. (the "Company"). Effective July 9, 1997, the
Company sold the Business to Synbiotics Corporation pursuant to purchase
agreements dated May 14, 1997 and amended July 9, 1997. The assets acquired
included inventory, property, plant and equipment and the rights to manufacture,
sell and distribute the product line.


Note 2 - Summary of Significant Accounting Policies:

Inventories

Inventories are stated at the lower of cost (first in, first out method) or
market.

Property and Equipment

Property and equipment are stated at cost.  Depreciation is computed using the
straight line method over the estimated useful lives of the related assets.


Note 3 - Basis of Presentation:

The accompanying statement of assets and statement of revenues and direct
operating expenses (the "Statements") have been prepared in accordance with
generally accepted accounting principles and were derived from Schedules 1 and 2
of the Rhone-Merieux SA Diagnostic Business Special Audit Report (the"Report")
contained elsewhere in this Form 8-K/A.  The Report presents financial data in
French francs.  The Statements have been converted to U.S. dollars using the
appropriate foreign currency exchange rates in effect for the periods presented.
Complete financial statements were not prepared as the Company did not maintain
the Business as a separate business unit and has not segregated indirect
operating cost information or related assets and liabilities (other than
inventory and property, plant and equipment) for this product line in its
accounting records.  It is not practical to attempt to reconstruct and separate
the indirect operating costs and other related assets and liabilities applicable
to this product line.

The Statements include the assets of the Company which are directly related to
the Business and which have been historically segregated by the Company in its
accounting records.  The Statements do not include cash, accounts receivable,
prepaid or other assets, accounts payable, accrued expenses, borrowings or any
other assets or liabilities.

The Statements include the revenues and direct operating expenses directly
attributable to the manufacture, sale and distribution of the product line
comprising the Business sold and have been historically segregated by the
Company in its accounting records.  The Statements also include an allocation of
certain expenses directly attributable to the manufacture, sale and distribution
of the product line and an allocation of research and development and general
and administrative expenses as discussed in the Report.  Management believes
that the above expense allocations are reasonable for the purpose of these
Statements; however, there can be no assurances that such allocations will be
indicative of future results of operations.

                                      -12-
<PAGE>
 
Rhone-Merieux SA Diagnostic Business

Statement of Assets (Unaudited)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
 
                                           June 30,
                                             1997
                                             ----
<S>                                      <C>  
Accounts receivable                      $  917,000
Inventories                               2,062,000
Property, plant and equipment, net          236,000
                                         ----------

  Total assets                           $3,215,000
                                         ==========
</TABLE> 

                See accompanying notes to financial statements.

                                      -13-
<PAGE>
 
Rhone-Merieux SA Diagnostic Business

Statement of Revenues and Direct Operating Expenses (Unaudited)
- -------------------------------------------------------------------------------

<TABLE> 
<CAPTION>  
                                                          Six Months
                                                          Ended June 30,
                                                              1997
                                                              ----
<S>                                                        <C> 
Revenues                                                   $5,760,000
                                                           ----------
Direct operating expenses:
  Cost of sales                                             2,027,000
  Research and development                                    518,000
  Selling and marketing                                       587,000
                                                           ----------

                                                            3,132,000
                                                           ----------

Excess of revenues over direct operating expenses          $2,628,000
                                                           ==========
</TABLE> 

                See accompanying notes to financial statements.

                                      -14-
<PAGE>
 
Rhone-Merieux SA Diagnostic Business

Notes to Unaudited Statement of Assets and Unaudited Statement of Revenues and 
Direct Operating Expenses
- -------------------------------------------------------------------------------

Note 1 - Business and Asset Purchase Agreement:

The Rhone-Merieux SA diagnostic business (the "Business") is a veterinary
diagnostic product line which is manufactured (however, certain small animal
diagnostic products are manufactured under contract by a third party), sold and
distributed by Rhone Merieux S.A.S. and R.M.- Diagnostics S.A.S., a wholly-owned
subsidiary of Rhone Merieux S.A.S., (collectively the "Company"). Effective July
9, 1997, the Company sold the Business to Synbiotics Corporation pursuant to
purchase agreements dated May 14, 1997 and amended July 9, 1997. The assets
acquired included accounts receivable, inventory, fixed assets and the rights to
manufacture, sell and distribute the product line.


Note 2 - Summary of Significant Accounting Policies:

Inventories

Inventories are stated at the lower of cost (first in, first out method) or
market.

Property and Equipment

Property and equipment are stated at cost.  Depreciation is computed using the
straight line method over the estimated useful lives of the related assets.


Note 3 - Basis of Presentation:

The accompanying unaudited statement of assets and unaudited statement of
revenues and direct operating expenses (the "Statements") have been prepared in
accordance with generally accepted accounting principles and were derived from
historical accounting records of the Company.  The interim data includes all
adjustments, consisting only of normal recurring adjustments, necessary for the
fair presentation of the results for the interim period; however, the interim
period does not include any allocation of overhead expenses as it is impractical
for the Company to provide the necessary data.  Complete financial statement
were not prepared as the Company did not maintain the Business as a separate
business unit and has not segregated indirect operating cost information or
related assets and liabilities (other than inventory and property, plant and
equipment) for this product line in its accounting records.  It is not practical
to attempt to reconstruct and separate the indirect operating costs and other
related assets and liabilities applicable to this product line.

The Statements include the assets of the Company which are directly related to
the Business and which have been historically segregated by the Company in its
accounting records. The Statements do not include cash, prepaid or other assets,
accounts payable, accrued expenses, borrowings or any other assets or
liabilities. The accounts receivable represent amounts owed to R.M.-Diagnostics
S.A.S. for inventory sold to Rhone Merieux S.A.S. who is acting as R.M.-
Diagnostics S.A.S's. distributor.

                                      -15-
<PAGE>
 
Rhone-Merieux SA Diagnostic Business

Notes to Unaudited Statement of Assets and Unaudited Statement of Revenues and 
Direct Operating Expenses
- ------------------------------------------------------------------------------

The Statements include the revenues and direct operating expenses directly
attributable to the manufacture, sale and distribution of the product line
comprising the Business sold and have been historically segregated by the
Company in its accounting records.

                                      -16-
<PAGE>
 
  b)  Pro forma financial information
      -------------------------------

      The following unaudited pro forma condensed balance sheet as of June 30,
      1997 and the unaudited pro forma condensed statements of operations for
      the year ended December 31, 1996 and the six months ended June 30, 1997
      giving effect to the acquisition of the worldwide veterinary diagnostic
      business of Rhone Merieux S.A.S. (the "Rhone Merieux Diagnostic Business")
      as of June 30, 1997 for the condensed balance sheet and as of January 1,
      1996 for the condensed statements of operations. The pro forma condensed
      financial statements are based on historical financial statements of
      Synbiotics Corporation and Rhone Merieux Diagnostic Business, giving
      effect to the acquisition applying the purchase method of accounting and
      the assumptions and adjustments as discussed in the accompanying notes to
      the pro forma condensed financial statements. The unaudited pro forma
      condensed financial statements do not include any consolidation savings
      which Synbiotics Corporation may expect to achieve from the merger of
      Synbiotics Corporation and Rhone Merieux Diagnostic Business as any such
      savings are not estimable at this time.

      These pro forma condensed financial statements have been prepared by the
      management of Synbiotics Corporation based upon the audited statement of
      operations of Synbiotics Corporation for the year ended December 31, 1996,
      the unaudited condensed balance sheet as of June 30, 1997 and the related
      unaudited condensed statement of operations for the six months then ended
      of Synbiotics Corporation, the unaudited statement of assets of Rhone
      Merieux Diagnostic Business as of June 30, 1997, the audited statement of
      revenues and direct operating expenses for the year ended December 31,
      1996 and the unaudited statement of revenues and direct operating expenses
      for the six months ended June 30, 1997 of Rhone Merieux Diagnostic
      Business. The unaudited pro forma condensed financial statements should be
      read in conjunction with the historical financial statements and notes
      thereto and narrative sections included elsewhere herein. The pro forma
      condensed financial statements are not necessarily indicative of what
      actual results of operations would have been for the periods had the
      transaction occurred on the dates indicated and do not purport to indicate
      future financial position nor the results of future operations.

                                      -17-
<PAGE>
 
Synbiotics Corporation
Pro Forma Condensed Balance Sheet (unaudited)
- -------------------------------------------------------------------------------

<TABLE>
<CAPTION>
                                                             June 30, 1997
                                         ------------------------------------------------------------------
                                                          Rhone Merieux
                                           Synbiotics       Diagnostic      Pro Forma          Pro Forma
                                           Corporation       Business      Adjustments         Combined
                                         --------------   -------------   -----------     -----------------
<S>                                      <C>              <C>             <C>             <C> 
Assets
 
Current assets:
 Cash and equivalents                    $    3,652,000   $               $               $       3,652,000
 Securities available for sale                2,181,000                                           2,181,000
 Accounts receivable                          3,123,000         917,000                           4,040,000
 Inventories                                  4,212,000       2,062,000                           6,274,000
 Deferred tax assets                            421,000                                             421,000
 Other current assets                           825,000                                             825,000
                                          -------------   -------------                   ----------------- 
 
   Total current assets                      14,414,000       2,979,000                          17,393,000
 
Property and equipment, net                     641,000         236,000                             877,000
Goodwill                                      5,358,000                    11,245,000 (1)        16,603,000
Deferred tax assets                           6,142,000                                           6,142,000
Other assets                                  1,592,000                                           1,592,000
                                         --------------   -------------                   ----------------- 

                                         $   28,147,000   $   3,215,000                   $      42,607,000
                                         ==============   =============                   =================

Liabilities and Shareholders' Equity

Current liabilities:
 Accounts payable and accrued expenses   $    1,761,000   $                               $       1,761,000
 Current portion of long-term debt                                          1,000,000 (1)         1,000,000
                                         --------------   -------------                   -----------------

   Total current liabilities                  1,761,000                                           2,761,000
                                         --------------   -------------                   -----------------

Long-term debt                                                              9,541,000 (1)         9,541,000
                                         --------------   -------------                   -----------------

Mandatorily redeemable common stock                                         2,747,000 (1)         2,747,000
                                         --------------   -------------                   -----------------


Non-mandatorily redeemable common
  stock and other shareholders' equity:
    Common stock                             35,432,000                       169,000 (1)        35,601,000
    Common stock warrants                                                   1,003,000 (1)         1,003,000
    Accumulated deficit                      (9,046,000)                                  $      (9,046,000)
                                         --------------   -------------                   -----------------
                                                                                          
    Total non-mandatorily redeemable
      common stock and other
      shareholders' equity                   26,386,000                                   $      27,558,000
                                         --------------   -------------                   ----------------- 

                                         $   28,147,000   $                               $      42,607,000
                                         ==============   =============                   =================
</TABLE> 
      See accompanying notes to pro forma condensed financial statements.

                                      -18-
<PAGE>
 
Synbiotics Corportation
Pro Forma Condensed Statement of Operations (unaudited)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>                                                        Year Ended December 31, 1996
                                                 ------------------------------------------------------------
                                                                 Rhone Merieux
                                                 Synbiotics       Diagnostic        Pro Forma          Pro Forma
                                                 Corporation       Business        Adjustments         Combined
                                                 -----------     -------------     -----------         ---------
<S>                                              <C>             <C>               <C>                 <C>

Net sales                                        $17,217,000     $11,735,000       $(1,760,000)(2)     $27,192,000
Cost of sales                                      9,572,000       5,015,000          (726,000)(3)      13,861,000
                                                 -----------     -----------                           -----------

Gross profit                                       7,645,000       6,720,000                            13,331,000
                                                 -----------     -----------                           -----------
Operating expenses:
 Research and development                            994,000       1,431,000          (234,000)(3)       2,191,000
 Selling and marketing                             4,183,000       3,109,000        (1,613,000)(3)       5,679,000
 General and administrative                        2,057,000       1,081,000          (383,000)(3)       3,505,000
                                                                                       750,000 (4)
                                                 -----------      ----------                           -----------

                                                   7,234,000       5,621,000                            11,375,000
                                                 -----------      ----------                           -----------

Income from operations                               411,000       1,099,000                             1,956,000

Interest income (expense),net                        204,000                        (1,053,000)(5)        (849,000)
Gain on sale of securities available for sale      1,159,000                                             1,159,000
Other income                                         410,000                                               410,000
                                                 -----------      ----------                           -----------

Income before income taxes                         2,184,000       1,099,000                             2,676,000

Income tax expense (benefit)                      (7,094,000)                           46,000 (6)      (7,048,000)
                                                 -----------      ----------                           -----------

Net income                                       $ 9,278,000     $ 1,099,000                           $ 9,724,000
                                                 ===========     ===========                           ===========

Net income per share                             $      1.47     $       n/a                           $      1.31
                                                 ===========     ===========                           ===========

Weighted average shares outstanding              $ 6,308,000             n/a           999,000 (7)       7,307,000
                                                 ===========     ===========                           ===========
</TABLE>

      See accompanying notes to pro forma condensed financial statements.

                                      -19-
<PAGE>
 
Synbiotics Corporation
Pro Forma Condensed Statement of Operations (unaudited)
- --------------------------------------------------------------------------------

<TABLE>
<CAPTION>
                                                   Six Months Ended June 30, 1997
                                    ---------------------------------------------------------------------
                                                     Rhone Merieux
                                        Synbiotics    Diagnostic        Pro Forma               Pro Forma
                                     Corporation       Business        Adjustments               Combined
                                    --------------   -------------   ----------------          ------------
<S>                                 <C>              <C>             <C>                       <C>
 
Net sales                            $  11,781,000   $   5,760,000   $   (864,000)(2)          $ 16,677,000
Cost of sales                            6,259,000       2,027,000         78,000 (3)             8,364,000
                                    --------------   -------------                             ------------
 
Gross profit                             5,522,000       3,733,000                                8,313,000
 
Operating expenses:
 Research and development                  613,000         518,000         70,000 (3)             1,201,000
 Selling and marketing                   2,324,000         587,000        147,000 (3)             3,058,000
 General and administrative              1,364,000                        343,000 (3)             2,082,000
                                                                          375,000 (4)
                                     -------------   -------------                             ------------

                                         4,301,000       1,105,000                                6,341,000
                                     -------------   -------------                             ------------

Income from operations                   1,221,000       2,628,000                                1,972,000
 
Interest income (expense), net             106,000                       (630,000)(5)              (524,000)            
Other income                               154,000                                                  154,000
                                     -------------   -------------                             ------------

Income before income taxes               1,481,000       2,628,000                                1,602,000

Provision for income taxes                 637,000                         97,000 (6)               734,000
                                     -------------   -------------                             ------------

Net income                           $     844,000   $   2,628,000                             $    868,000
                                     =============   =============                             ============

Net income per share                 $         .11   $         n/a                             $        .09
                                     =============   =============                             ============

Weighted average shares outstanding      7,499,000             n/a        999,000 (7)             8,498,000
                                     =============   =============                             ============
</TABLE> 

      See accompanying notes to pro forma condensed financial statements.

                                      -20-
<PAGE>
 
Synbiotics Corporation
Notes to Pro Forma Condensed Financial Statements (unaudited)
- -------------------------------------------------------------------------------

Note (1)

Adjustment to record the acquisition of Rhone Merieux Diagnostic Business.
Consideration paid comprises $10,541,000 of debt obtained from Banque Paribas,
net of issuance costs and $2,747,000 of Synbiotics Corporation mandatorily
redeemable common stock (759,000 shares issued at $4.1875 per share), net of
issuance costs.  In addition, Synbiotics issued to Banque Paribas a warrant to
purchase 240,000 of Synbiotics Corporation common stock for $.01 per share.

Note (2)

Adjustment to reduce Rhone Merieux Diagnostic Business net sales to reflect
distributor mark downs.  Prior to the acquisition, the products were sold
direct, whereas subsequent to the acquisition the products will be sold
primarily through distributors.

Note (3)

Adjustment to increase (reduce) the direct operating expenses of Rhone Merieux
Diagnostic Business to reflect Synbiotics Corporation's overhead.

Note (4)

Adjustment to record amortization of the goodwill acquired from Rhone Merieux
Diagnostic Business based on a 15 year amortization period.

Note (5)

Adjustment to record interest expense related to the debt obtained from Banque
Paribas.

Note (6)

Adjustment to record foreign income tax provision related to the taxable income
from Rhone Merieux Diagnostic Business, and to reduce the U.S. tax provision for
the tax effect of additional deductible amounts related to goodwill and interest
expense.

Note (7)

Adjustment to reflect increase in weighted average shares outstanding due to the
issuance of Synbiotics Corporation mandatorily redeemable common stock and
common stock warrants (Note (1)).

                                      -21-
<PAGE>

<TABLE> 
<CAPTION> 
 
     c)  Exhibits
         --------
           <C>    <S>  
           2.4.1  Amendment No. 1 to Asset Purchase Agreement between Rhone
                  Merieux, Inc. and the Registrant, dated July 9, 1997.

           2.4.2  Amendment No. 2 to Asset Purchase Agreement between Rhone
                  Merieux, Inc. and the Registrant, dated July 9, 1997.

           2.5.1  Amendment No. 1 to Stock Purchase Agreement between Rhone
                  Merieux S.A.S., Institut De Selection Animale S.A., R.M. -
                  Diagnostics S.A.S. and the Registrant, dated July 9, 1997.

           2.5.2  Amendment No. 2 to Stock Purchase Agreement between Rhone
                  Merieux S.A.S., Institut De Selection Animale S.A., R.M. -
                  Diagnostics S.A.S. and the Registrant, dated July 9, 1997.
</TABLE> 

                                  SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                         SYNBIOTICS CORPORATION


Date:  September 22, 1997                /s/ Michael K. Green
                                         --------------------
                                         Michael K. Green
                                         Vice President of Finance and 
                                         Chief Financial Officer

                                      -22-
<PAGE>
 
                      SECURITIES AND EXCHANGE COMMISSION

                               WASHINGTON, D.C.


                                   EXHIBITS

                                      TO

                                   FORM 8-K

                                     UNDER

                        SECURITIES EXCHANGE ACT OF 1934

                            SYNBIOTICS CORPORATION


<PAGE>
 
                                 EXHIBIT INDEX
<TABLE> 
<CAPTION> 

Exhibit No.    Exhibit
- -----------    -------
<C>            <S>  

2.4.1          Amendment No. 1 to Asset Purchase Agreement between Rhone
               Merieux, Inc. and the Registrant, dated July 9, 1997.

2.4.2          Amendment No. 2 to Asset Purchase Agreement between Rhone
               Merieux, Inc. and the Registrant, dated July 9, 1997.

2.5.1          Amendment No. 1 to Stock Purchase Agreement between Rhone Merieux
               S.A.S., Institut De Selection Animale S.A., R.M. - Diagnostics
               S.A.S. and the Registrant, dated July 9, 1997.

2.5.2          Amendment No. 2 to Stock Purchase Agreement between Rhone Merieux
               S.A.S., Institut De Selection Animale S.A., R.M. - Diagnostics
               S.A.S. and the Registrant, dated July 9, 1997.
</TABLE> 
         

<PAGE>
 
                                                                   Exhibit 2.4.1
                                                                   -------------

                                AMENDMENT NO. 1
                                      TO
                           ASSET PURCHASE AGREEMENT


     This Amendment No. 1 dated July 9, 1997, to the Asset Purchase Agreement
(the "Agreement") dated as of the 14th day of May, 1997 by and between
Synbiotics Corporation, a California corporation with its principal office at
11011 Via Frontera, San Diego, CA 92127 (the "Buyer"), and Rhone Merieux, Inc.,
a Georgia corporation with its principal office at 115 Transtech Drive, Athens,
Georgia 30601 (the "Seller").

     WHEREAS, the parties wish to amend the Agreement as set forth below to
reflect their agreement on the adjustment of the purchase price of the assets
being purchased thereunder, subject to the condition that the distribution of
certain products begin before the end of 1997.  Capitalized terms used herein
and not otherwise defined shall have the meanings assigned to them in the
Agreement:

     1.   Notwithstanding Section 1.1(a)(i) of the Agreement, the Buyer and the
Seller agree that the Seller shall not sell at the Closing, and the Buyer shall
not purchase, any inventories of finished goods or packing materials of the
"Witness" products, and Seller shall retain ownership of such finished goods and
materials and shall either (i) return such finished goods and materials to the
supplier thereof or (ii) sell such finished goods and materials to the Buyer
from time to time in accordance with Section 1.6 of the Agreement.

     2.   In Section 1.2 of the Agreement, the words "Four Million Two Hundred
Thousand U.S. Dollars ($4,200,000)" are replaced with "Two Million Eight Hundred
and Fifty Thousand U.S. Dollars ($2,850,000)".

     3.   The existing text of Section 1.2 of the Agreement is redesignated as
paragraph (a) of Section 1.2. and the words "provided that if... " through "as
soon as practicable," are deleted.  The following new paragraph (b) is added
thereafter:

          "(b) (1) If, prior to January 1, 1998, (i) the Buyer or any of its
          Affiliates makes a commercial sale in the United States of any
          Heartworm Product (as defined below), approved for sale by the USDA in
          any form, or (ii) if the U.S. patent rights on technology relating to
          any Heartworm Product are licensed, sublicensed or given by the Buyer
          or any of its Affiliates to any third party (other than for the sole
          purpose of enabling such third party to manufacture or resell
          Heartworm Products on behalf of the Buyer or one of its Affiliates),
          the Buyer shall immediately inform the Seller of such event and pay to
          the Seller a sum equal to the 

                                      -1-
<PAGE>
 
          product of One Hundred Thousand U.S. Dollars ($100,000) times the
          number of full calendar months between the date of such event and
          December 31, 1997, by wire transfer of immediately available funds to
          an account designated by the Seller no later than thirty days after
          the date of occurrence of such event. If, prior to January 1, 1998,
          (i) the Buyer or any of its Affiliates makes a commercial sale in the
          United States of any FeIV Product (as defined below) in any form, or
          if the U.S. patent rights on technology related to any FeIV Product
          are licensed, sublicensed or given by the Buyer or any of its
          Affiliates to any third party (other than for the sole purpose of
          enabling such third party to manufacture or resell FeIV Products on
          behalf of the Buyer or one of its Affiliates), then Buyer shall
          immediately inform the Seller of such event and pay to the Seller
          Three Hundred and Fifty Thousand U.S. Dollars ($350,000) by wire
          transfer of immediately available funds to an account designated by
          the Seller no later than thirty days after the date of occurrence of
          such event. For purposes of this Agreement the terms "Heartworm
          Product" and "FeIV Product" shall mean the Witness Heartworm product
          and the Witness FeIV products, respectively, of the Seller as they
          existed in their form of an antigen caught in between two monoclonal
          antibodies on the date of the Closing and as such products may be
          modified from time to time by or for the Buyer, regardless of the
          trademarks under which these products are sold.

          (2)  If, before January 1, 1998, the Buyer obtains from a third party
          a patent or technology license in order to avoid patent or technology
          infringement claims in connection with the commercial introduction in
          the United States of an FeIV Product, the cost of such license
          (including all up front payments and the net present value discounted
          at an annual rate of 14% of all future royalties or other similar
          payments due from the Buyer or its Affiliates to the licensor for a
          period of the remaining duration of the patent or four (4) years,
          whichever is shorter), up to a maximum of One Hundred and Seventy-Five
          Thousand U.S. Dollars ($175,000), shall be deducted from the Three
          Hundred Fifty Thousand U.S. Dollars ($350,000) to be released in
          connection with the corresponding FeIV release, and no price
          supplement shall be due by RM under new Section 1.6 of the Stock
          Purchase Agreement, as amended.

     4.   Clause (d) of Section 1.6 is amended by adding to the end thereof,
before the semi-colon, the following "or return any items of Retained Inventory
to the manufacturer."

                                      -2-
<PAGE>
 
     5.   Section 1.7 of the Agreement is deleted.

     6.   Section 6.9 of the Agreement is deleted.

     7.   The first clause of Section 8.5 of the Agreement up to the first
proviso, is amended to read as follows:

          "8.5 Limitations on Liability.  The liability of the Seller for
          indemnification hereunder shall be limited to the sum of (a)
          $13,533,690 plus (b) all amounts paid to the Seller pursuant to
          Section 1.2(b) of this Agreement, plus (c) the amount of the Earn-Out
          Payment, if any, actually paid to RM pursuant to the Stock Purchase
          Agreement (collectively the "Indemnification Amount");".

     8.   The Buyer hereby waives for itself and for any of its Affiliates any
rights it or they may have under Section 8 of the Agreement as a result of any
claim or action by any third party alleging an infringement of a United States
patent or U.S. intellectual property rights arising out of any sale after the
Closing by the Buyer or its Affiliates or licensees of Heartworm Products or
FeIV Products.  The Buyer hereby represents that it is aware of the risks of
U.S. patent infringement associated with these products and assumes such risks
to the extent set forth in this Section 6.

     9.   This Amendment No. 1 may be executed in one or more counterparts, each
of which shall be deemed to be an original, but all of which shall be one and
the same document.

IN WITNESS WHEREOF, this Amendment No. 1 to the Agreement has been duly
executed by the parties hereto and is effective as of the date first above
written.


                                       SYNBIOTICS CORPORATION

                                       By:  /s/ Kenneth M. Cohen
                                            --------------------
                                            Name: Kenneth M. Cohen,
                                             President and Chief Executive
                                             Officer


                                       RHONE MERIEUX, INC.

                                       By:  /s/ Kyle W. Lathrop
                                            -------------------
                                       Name: Kyle W. Lathrop
                                       Title: General Counsel/Proxy

                                      -3-

<PAGE>
 
                                                                   Exhibit 2.4.2
                                                                   -------------

                                AMENDMENT NO. 2
                                      TO
                           ASSET PURCHASE AGREEMENT



This Amendment No. 2 dated July 9, 1997, to the Asset Purchase Agreement (the
"Agreement") dated as of the 14th day of May, 1997 by and between Synbiotics
Corporation, a California corporation with its principal office at 11011 Via
Frontera, San Diego, CA 92127 (the "Buyer"), and Rhone Merieux, Inc., a Georgia
corporation with its principal office at 115 Transtech Drive, Athens, Georgia
30601 (the "Seller").

     The parties wish to amend the Agreement as set forth below.  Capitalized
terms used herein and not otherwise defined shall have the meanings assigned to
them in the Agreement:

     1.   The Seller hereby (a) acknowledges that the Buyer is pledging and
assigning its rights, but not its obligations, under each of the Agreement and
the Distribution Agreement to the Banks (as hereinafter defined) under that
certain Credit Agreement dated the date hereof (the "Credit Agreement") among
the Buyer, Banque Paribas, as agent, and the Banks named therein (the "Banks"),
and (b) consents to such pledge and assignment.

     2.   In all other respects, the Agreement shall remain unamended and in
full force and effect.

     3.   This Amendment No. 2 may be executed in one or more counterparts, each
of which shall be deemed to be an original, but all of which shall be one and
the same document.

IN WITNESS WHEREOF, this Amendment No. 2 to the Agreement has been duly executed
by the parties hereto as of and on the date first above written.


                                          BUYER:

                                          SYNBIOTICS CORPORATION

                                          By:  /s/ Kenneth M. Cohen
                                               --------------------
                                               Name: Kenneth M. Cohen,
                                                President and Chief Executive
                                                Officer



                                          SELLER:

                                          RHONE MERIEUX, INC.

                                          By: /s/ Kyle W. Lathrop
                                              -------------------
                                          Name: Kyle W. Lathrop
                                          Title: General Counsel/Proxy

                                      -1-

<PAGE>
 
                                                                   Exhibit 2.5.1
                                                                   -------------

                                AMENDMENT NO. 1
                                       TO
                            STOCK PURCHASE AGREEMENT


This Amendment No. 1 dated July 9, 1997 to the Stock Purchase Agreement (the
"Agreement") dated as of the 14th day of May, 1997 by and among Synbiotics
Corporation, a California corporation with its principal office at 11011 Via
Frontera, San Diego, CA 92127 (the "Buyer"), and Rhone Merieux, S.A.S., a French
societe par actions simplifiee with its registered office at 17, rue Bourgelat,
69002 Lyon, France ("RM"), Institut de Selection Animale S.A., a French societe
anonyme with its principal place of business at 119, avenue Marechal de Saxe,
69003 Lyon, France ("ISA") (each of RM and ISA is referred to herein as a
"Seller" and collectively as the "Sellers"), and R.M.- Diagnostics S.A.S. a
French societe par actions simplifiee, with its registered office at 299, avenue
Jean Jaures, 69007 Lyon, France (the "Company").

     WHEREAS, the parties wish to amend the Agreement as set forth below to
reflect their agreement on an adjustment of the purchase price for the shares of
the Company based upon the date of release on the market of certain products.
Capitalized terms used herein and not otherwise defined shall have the meanings
assigned to them in the Agreement is amended to read in its entirety as follows:

     1.   Paragraph (a) (ii) of Section 1.3 of the Agreement is amended to read
in its entirety as follows:

          "(ii) Seven Hundred Fifty-Nine Thousand Eighteen (759,018) shares of
          the Common Stock, no par value ("Synbiotics Common Stock"), of the
          Buyer (the "Buyer Shares").  At the Closing, Two Hundred Thirty
          Thousand (230,000) of the Buyer Shares (the "Escrow Shares") shall be
          placed in escrow with the Buyer, to be released to RM or to the Buyer,
          as the case may be, upon the occurrence of the following events:

          (A)  One Hundred Seventy One Thousand Six Hundred (171,600) Escrow
          Shares will be released to RM immediately upon the occurrence,  prior
          to January 1, 1998, of either of the following events: (i) on the date
          of the first commercial sale in the United States of any Heartworm
          Products (as defined below) by the Buyer or any of its Affiliates
          approved for sale by the USDA in any form or (ii) if the US. patents
          rights on technology relating to any Heartworm Product are licensed,
          sublicensed or given by the Buyer or any of its Affiliates to any
          third party (other than for the sole purpose of enabling such third
          party to manufacture or resell Products on behalf of the Buyer or one
          of its Affiliates) (a "Heartworm Release");

                                      -1-
<PAGE>
 
          (B)  Fifty Eight Thousand Four Hundred (58,400) Escrow Shares will be
          released to RM immediately upon the occurrence, prior to January 1,
          1998, of either of the following events: (i) on the date of the first
          commercial sale in the United States of any FeIV Product (as defined
          below) by the Buyer or any of its Affiliates approved for sale by the
          USDA in any form, or (ii) if the U.S. patent rights on technology
          relating to any FeIV Product are licensed, sublicensed or given by the
          Buyer or any of its Affiliates to any third party (other than for the
          sole purpose of enabling such third party to manufacture or resell
          FeIV Products on behalf of the Buyer or one of its Affiliates) (an
          "FeIV Release");

          (C)  if a Heartworm Release has not taken place before January 1,
          1998, the number of Escrow Shares released to RM in connection with a
          Heartworm Release, if any, will be reduced by Twenty Five Thousand
          (25,000) for each of the first four full months elapsed between
          January 1, 1998 and the date of the Heartworm Release and then by
          Eight Thousand Six Hundred (8,600) per full month lapsed thereafter
          prior to a Heartworm Release, on the first day of the following month,
          until none of these One Hundred Seventy One Thousand Six Hundred
          (171,600) Escrow Shares remains to be released to RM.  Escrow Shares
          so deducted shall revert in full ownership to the Buyer as of the date
          they are deducted;

          (D)  if an FeIV Release has not taken place before January 1, 1998,
          the number of Escrow Shares released to RM in connection with a FeIV
          Release, if any, will be reduced by Three Thousand Two Hundred and
          Forty (3,240) for each full month lapsed between January 1, 1998 and
          the date of the FeIV Release, on the first day of the following month,
          until none of these Fifty Eight Thousand Four Hundred (58,400) Escrow
          Shares remains to be released to RM; provided that if the Buyer at any
          time prior to the second anniversary of the date of the Closing,
          commercially introduces any FeIV Product in the form of an antigen
          caught in between two monoclonal antibodies into the U.S. market
          (whether directly or through an intermediary), all such 58,400 Escrow
          Shares shall be immediately released to RM.  Any portion of such
          58,400 not required to be released to RM as of the second anniversary
          of the date of the Closing shall revert in full ownership to the
          Buyer;

          (E)  for purposes of this Agreement, the terms "Heartworm Product" and
          "FeIV Product" shall mean the Witness Heartworm product and the
          Witness FeIV product, respectively, of Rhone Merieux Inc. as they
          existed in their form of antigen caught in-between monoclonal
          antibodies form on the date of the Closing and as such products may be
          modified from time to time by or for the Buyer, regardless of the
          trademarks, under which the products are sold;

                                      -2-
<PAGE>
 
          (F)  unless and until Escrow Shares are released to RM in accordance
          with this clause 1.3(a)(ii), Seller shall have no rights of ownership
          with respect to such Escrow Shares, including without limitation the
          right to transfer (other than to the Buyer), to vote or to receive
          dividends with respect to such Escrow Shares; provided, however, that
          any dividends paid with respect to the Escrow Shares, while held in
          escrow, shall accrue to the benefit of the party (RM or the Buyer) to
          which such Escrow Shares are ultimately released, and shall be paid to
          such party (and in the case of a release to RM, together with interest
          thereon at the prime lending rate of The Bank of America) upon the
          release of the corresponding Escrow Shares from escrow; plus".


     2.   The following text is added as a new paragraph at the end of Section
1.3(a) of the Agreement:

          "The number of shares to be received by the Sellers under Section
          1.3(a)(ii) shall be reduced if the aggregate net book value of the
          Inventory of RM, Inc. on the Date of the Closing is less than 100% of
          the net book value of the Inventory at December 31, 1996 (an
          "Inventory Deficit").  RM shall inform the Buyer two business days
          prior to the Closing whether it expects there to be an Inventory
          Deficit and, if so, the anticipated amount of such Inventory Deficit
          as of the Date of the Closing.  In the event that there is an
          anticipated Inventory Deficit, the number of shares to be received by
          the Sellers will be reduced by the amount of the anticipated Inventory
          Deficit, with a reconciliation based on the finally calculated actual
          Inventory Deficit to occur as soon as practicable.  For that purpose,
          the price per share shall be 5.00 U.S. Dollars.

          All capitalized terms appearing in this paragraph and not otherwise
          defined in this Agreement shall have the meaning assigned thereto in
          the U.S. Purchase Agreement.  Any and all references to the number of
          Buyer Shares shall be amended accordingly in this Agreement and any
          agreement executed in its application."

     3.   Section 1.6 is renumbered Section 1.7 and otherwise left unchanged.

     4.   The following new Section 1.6 is added:

              "1.6  Price Supplement.  No later than thirty days after the third
                    -----------------                                           
          anniversary of the date of registration with the USDA of the Heartworm
          Product under any trademark (the "Heartworm Registration Date"), the
          Buyer shall pay to RM by wire transfer of immediately available funds
          denominated in U.S. Dollars, 

                                      -3-
<PAGE>
 
          to an account designated by RM, as a price supplement, an amount equal
          to five percent (5%) of the total aggregate North American sales of
          Heartworm Products by the Buyer, its Affiliates and licensees for such
          products during the three year period following the Heartworm
          Registration Date, up to a maximum of Five Hundred Thousand U.S.
          Dollars ($500,000). No later than thirty days after the third
          anniversary of the date of registration with the USDA of the FeIV
          Product under any trademark (the "FeIV Registration Date"), the Seller
          shall pay to RM, by wire transfer of immediately available funds
          denominated in U.S. Dollars, to an account designated by RM, as a
          price supplement, an amount equal to five percent (5%) of the total
          aggregate North American sales of FeIV Products by the Buyer, its
          Affiliates and licensees for such products, during the three year
          period following the FeIV Registration Date, up to a maximum of One
          Hundred Seventy-Five Thousand U.S. Dollars ($175,000). No price
          supplement relating to FeIV shall be due under this Section 1.6 if the
          adjustment described under Section 1.2(b)(2) of the Asset Purchase
          Agreement, as amended, is made under this Section 1.6."

     5.   On the 6th line of Section 3.4 (a), the words "May 31, 1997," are
replaced by "June 30, 1997".

     6.   The first clause of Section 10.5 of the Agreement up to the first
proviso, is amended to read as follows:

          "10.5 Limitations on Liability.  The liability of RM for
          indemnification hereunder shall be limited to the sum of (a)
          $13,533,690 plus (b) all amounts paid to RM Inc. pursuant to Section
          1.2(b) of the U.S. Purchase Agreement, as amended, plus (c) the amount
          of the Earn-Out Payment, if any, actually paid to the Sellers pursuant
          to Section 1.5 hereof (collectively, the "Indemnification Amount")."

     7.   The Buyer hereby irrevocably waives for itself and any of its
Affiliates any rights it or they may have under Section 10 of the Agreement as a
result of any claim or action by any third party alleging an infringement of a
United States patent or U.S. intellectual property rights arising out of any
sale after the Closing by the Buyer or its Affiliates or licensees of Heartworm
Products or FeIV Products.  The Buyer hereby represents that it is aware of the
risks of U.S. Patent infringement associated with these products and assumes
such risks to the extent set forth in this Section 7.

     8.   This Amendment No. 1 may be executed in one or more counterparts, each
of which shall be deemed to be an original, but all of which shall be one and
the same document.

                                      -4-
<PAGE>
 
IN WITNESS WHEREOF, this Amendment No. 1 to the Agreement has been duly executed
by the parties hereto and is effective as of the date first above written.


                                        SYNBIOTICS CORPORATION

                                        By:  /s/ Kenneth M. Cohen
                                             --------------------
                                             Name: Kenneth M. Cohen,
                                              President and Chief Executive
                                              Officer


                                        R.M. - DIAGNOSTICS S.A.S.

                                        By: /s/ Phillipe Martin-Jarand
                                            --------------------------
                                        Name:  Phillipe Martin-Jarand
                                        Title:


                                        RHONE MERIEUX S.A.S.

                                        By: /s/ Phillipe Martin-Jarand
                                            --------------------------
                                        Name:  Phillipe Martin-Jarand
                                        Title:


                                        INSTITUT DE SELECTION ANIMAL S.A.

                                        By: /s/ Phillipe Martin-Jarand
                                            --------------------------
                                        Name:  Phillipe Martin-Jarand
                                        Title:

                                      -5-

<PAGE>
 
                                                                   Exhibit 2.5.2
                                                                   -------------

                                AMENDMENT NO. 2
                                       TO
                            STOCK PURCHASE AGREEMENT


     This Amendment No. 2 dated July 9, 1997, to the Stock Purchase Agreement
(the "Agreement") dated as of the 14th day of May 7, 1997 by and among
Synbiotics Corporation, a California corporation with its principal office  at
11011 Via Frontera, San Diego, CA 92127 (the "Buyer"), and Rhone Merieux,
S.A.S., a French societe par actions simplifiee with its registered office at
17, rue Bourgelat, 69002 Lyon, France ("RM"), Institut de Selection Animale
S.A., a French societe anonyme with its principal place of business at 119,
avenue Marechal de Saxe, 69003 Lyon, France ("ISA") (each of RM and ISA is
referred to herein as a "Seller" and collectively as the "Sellers"), and R.M.-
Diagnostics S.A.S. a French societe par actions simplifiee, with its registered
office at 299, avenue Jean Jaures, 69007 Lyon, France (the "Company").

     The parties wish to amend the Agreement as set forth below.  Capitalized
terms used herein and not otherwise defined shall have the meanings assigned to
them in the Agreement:

     1.   Each of the Sellers and the Company hereby (a) acknowledges that the
Buyer is pledging and assigning its rights, but not its obligations, under each
of the Agreement, the Stock Restriction and Rights Agreement, the Supply
Agreement, the Services Agreement, the R&D Agreement, the Trademark License
Agreement and the Distribution Agreements to the Banks (as hereinafter defined)
under that certain Credit Agreement dated the date hereof (the "Credit
Agreement") among the Buyer, Banque Paribas, as agent, and the Banks named
therein (the "Banks"), and (b) consents to such pledge and assignment.

     2.   The Sellers hereby acknowledge that, in accordance with the Credit
Agreement, the Buyer will issue to Banque Paribas, as agent for the Banks,
Common Stock Purchase Warrants to purchase up to an aggregate of 239,950 shares
of Synbiotics Common Stock, and the Buyer's representations and warranties set
forth in Section 4.2 of the Agreement and in Schedule 4.2 to the Agreement are
hereby deemed to be amended to disclose the issuance of such Common Stock
Purchase Warrants.

     3.   In all other respects, the Agreement shall remain unamended and in
full force and effect.

     4.   This Amendment No. 2 may be executed in one or more counterparts, each
of which shall be deemed to be an original, but all of which shall be one and
the same document.

                                      -1-
<PAGE>
 
IN WITNESS WHEREOF, this Amendment No. 2 to the Agreement has been duly executed
by the parties hereto as of and on the date first above written.


                                        SYNBIOTICS CORPORATION

                                        By:  /s/ Kenneth M. Cohen
                                             --------------------
                                             Name: Kenneth M. Cohen,
                                              President and Chief Executive
                                              Officer


                                        R.M. - DIAGNOSTICS S.A.S.

                                        By: /s/ Phillipe Martin-Jarand
                                            --------------------------
                                        Name:  Phillipe Martin-Jarand
                                        Title:


                                        RHONE MERIEUX S.A.S.

                                        By: /s/ Phillipe Martin-Jarand
                                            --------------------------
                                        Name:  Phillipe Martin-Jarand
                                        Title:


                                        INSTITUT DE SELECTION ANIMAL S.A.

                                        By: /s/ Phillipe Martin-Jarand
                                            --------------------------
                                        Name:  Phillipe Martin-Jarand
                                        Title:

                                      -2-


© 2022 IncJournal is not affiliated with or endorsed by the U.S. Securities and Exchange Commission