SYNBIOTICS CORP
PRE 14A, 1999-04-22
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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<PAGE>
 
================================================================================
 
                           SCHEDULE 14A INFORMATION

                  Proxy Statement Pursuant to Section 14(a) 
                    of the Securities Exchange Act of 1934 
        
Filed by the Registrant [X]

Filed by a Party other than the Registrant [_] 

Check the appropriate box:

[X]  Preliminary Proxy Statement        
                                        
[_]  Definitive Proxy Statement 

[_]  Definitive Additional Materials 

[_]  Soliciting Material Pursuant to Rule 14a-11(c) or Rule 14a-12

                            SYNBIOTICS CORPORATION
- --------------------------------------------------------------------------------
               (Name of Registrant as Specified In Its Charter)


- --------------------------------------------------------------------------------
   (Name of Person(s) Filing Proxy Statement, if Other Than the Registrant)

   
Payment of Filing Fee (Check the appropriate box):

[X]  No fee required.

[_]  $125 per Exchange Act Rules 0-11(c)(1)(ii), 14a-6(i)(1), or 14a-6(i)(2) or 
     Item 22(a)(2) of Schedule 14A.

[_]  $500 per each party to the controversy pursuant to Exchange Act Rule 
     14a-6(i)(3).

[_]  Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.

   
     (1) Title of each class of securities to which transaction applies:

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     (2) Aggregate number of securities to which transaction applies:

     -------------------------------------------------------------------------


     (3) Per unit price or other underlying value of transaction computed
         pursuant to Exchange Act Rule 0-11:

     -------------------------------------------------------------------------
      

     (4) Proposed maximum aggregate value of transaction:

     -------------------------------------------------------------------------


     (5) Total fee paid:

     -------------------------------------------------------------------------

[_]  Fee paid previously with preliminary materials.
     
[_]  Check box if any part of the fee is offset as provided by Exchange
     Act Rule 0-11(a)(2) and identify the filing for which the offsetting fee
     was paid previously. Identify the previous filing by registration statement
     number, or the Form or Schedule and the date of its filing.
     
     (1) Amount Previously Paid:
 
     -------------------------------------------------------------------------


     (2) Form, Schedule or Registration Statement No.:

     -------------------------------------------------------------------------


     (3) Filing Party:
      
     -------------------------------------------------------------------------


     (4) Date Filed:

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<PAGE>
 
                            SYNBIOTICS CORPORATION
 
                               ----------------
 
                   NOTICE OF ANNUAL MEETING OF SHAREHOLDERS
                            To Be Held June 9, 1999
 
  The Annual Meeting of Shareholders of Synbiotics Corporation will be held at
the Radisson Suite Hotel (Rancho Bernardo), 11520 West Bernardo Court, San
Diego, California 92127, on June 9, 1999 at 10:00 a.m. for the following
purposes:
 
 
  1. To elect seven directors;
 
  2. To consider a proposal to amend the 1995 Stock Option/Stock Issuance
     Plan;
 
and to transact such other business as may properly come before the meeting
and any postponement or adjournment thereof.
 
  The Board of Directors has fixed April 16, 1999, as the record date for
determining the shareholders entitled to notice of and to vote at the Annual
Meeting and any postponement or adjournment thereof.
 
  WE WOULD BE GRATEFUL IF YOU WOULD PROMPTLY SIGN AND RETURN THE ENCLOSED
PROXY CARD.
 
                                          Michael K. Green
                                          Secretary
 
May 3, 1999
<PAGE>
 
                                PROXY STATEMENT
 
  This Proxy Statement is furnished in connection with the solicitation by the
Board of Directors of Synbiotics Corporation, a California corporation (the
"Company"), 11011 Via Frontera, San Diego, California 92127, of proxies in the
accompanying form to be used at the Annual Meeting of Shareholders to be held
at the Radisson Suite Hotel (Rancho Bernardo), 11520 West Bernardo Court, San
Diego, California 92127, at 10:00 a.m. on June 9, 1999, and any postponement
or adjournment thereof.
 
  A proxy may be revoked at any time before it is exercised. Any shareholder
giving a proxy may revoke it prior to its use at the Annual Meeting (1) by
delivering a written notice expressly revoking the proxy to the Company's
Secretary at the Company's offices, (2) by signing and delivering to the
Company at its offices, or to the place of the Annual Meeting, a later dated
proxy or (3) by attending the Annual Meeting and casting his or her votes
personally. A proxy is not revoked by the death or incapacity of the maker
unless, before the vote is counted, written notice of such death or incapacity
is received by the Company.
 
  On the matters coming before the Annual Meeting as to which a choice has
been specified by the shareholder on the proxy, the shares will be voted
accordingly. If the proxy is returned and no choice is so specified, the
shares will be voted FOR the election of the seven nominees for director
listed in this Proxy Statement, FOR the approval of proposal 2 described in
the Notice of Meeting and this Proxy Statement, and in the discretion of the
proxyholders as to any other business which may properly come before the
Annual Meeting.
 
  April 16, 1999, has been fixed as the record date for determining the
shareholders entitled to notice of and to vote at the Annual Meeting. As of
the close of business on such date, the Company had 8,973,238 shares of common
stock outstanding and entitled to vote. Outstanding shares of common stock are
entitled to one vote each on all matters. Under California law, shareholders
are permitted to cumulate votes for the election of directors whose names have
been placed in nomination. Therefore, in voting for directors, each
outstanding share of common stock would be entitled to seven votes which may
be cast for one candidate or distributed in any manner among the nominees for
director. However, the right to cumulate votes in favor of one or more
candidates may not be exercised until the candidate or candidates have been
nominated and any shareholder has given notice at the Annual Meeting of the
intention to cumulate votes.
 
  The proxyholders (if authority to vote for one or more nominees is not
withheld) will have full discretion and authority to vote cumulatively and to
allocate votes among any or all of the Board of Directors nominees as they may
determine or, if authority to vote for a specified candidate or candidates has
been withheld, among those candidates for whom authority to vote has not been
withheld.
 
  The expense of printing and mailing proxy material will be borne by the
Company. The approximate date these proxy solicitation materials will be first
sent to shareholders is May 3, 1999.
<PAGE>
 
                             ELECTION OF DIRECTORS
                          (Item 1 on the Proxy Card)
 
  Seven directors are to be elected at the Annual Meeting to serve until the
next Annual Meeting and until their respective successors are elected or
appointed. Unless authority to vote for one or more nominees is withheld, it
is intended that the proxyholders will vote for the election of the nominees
named below. In the event any of them shall become unable or unwilling to
accept nomination or election, the shares represented by the enclosed proxy
will be voted for the election of such other person as the Board of Directors
may recommend in his or her place. Each of the nominees named is currently a
member of the Board of Directors of the Company.
 
  The following information is furnished regarding the nominees of the
Company.
 
<TABLE>
<CAPTION>
          Name; Positions; Business Experience During the           Director
       Past Five Years; Directorships in Reporting Companies         Since   Age
       -----------------------------------------------------        -------- ---
<S>                                                                 <C>      <C>
Patrick Owen Burns.................................................   1997    61
 Senior Consultant of Early Stage Enterprises, L.L.C. since October
 1997; Vice President of R&D Funding Corp, an affiliate of
 Prudential Securities Inc., and Senior Vice President of
 Prudential Securities Inc. from 1986 to February, 1997; Director
 of Progen Industries, Ltd.
 
Kenneth M. Cohen...................................................   1996    44
 President and Chief Executive Officer of the Company since May
 1996; Executive Vice President and Chief Operating Officer of
 Canji, Inc. from March 1995 to February 1996; Vice President of
 Argus Pharmaceuticals, Inc. from May 1990 to March 1995.
 
James C. DeCesare..................................................   1993    68
 Consultant to the animal health and pharmaceutical industries
 since 1992.
 
Brenda D. Gavin, DVM...............................................   1996    50
 Becomes President of S. R. One, Limited, a venture capital firm,
 in May 1999; Vice President of S. R. One, Limited from 1989 to
 April 1999; Director of Oxis International, Inc.
 
M. Blake Ingle, Ph.D. .............................................   1994    57
 Private investor; President and Chief Executive Officer of Canji,
 Inc. March 1993 to February 1996; Acting President of Telios
 Pharmaceuticals, Inc. from December 1994 to June 1995; Director of
 Corvas International, Inc. and Vical, Inc.
 
Joseph Klein III...................................................   1998    38
 Healthcare Analyst for The Kaufmann Fund since June 1998;
 Portfolio Manager and Chairman of Investment Advisory Committee of
 T. Rowe Price Health Sciences Fund from December 1995 to February
 1998; Vice President and Healthcare Analyst of T. Rowe Price
 Associates, Inc. from April 1990 to February 1998; Director of
 Guilford Pharmaceuticals, Inc. and NPS Pharmaceuticals, Inc.
 
Donald E. Phillips.................................................   1987    66
 Private investor; Chairman of the Board of Directors of the
 Company since August 1994; Vice Chairman of the Board of Directors
 of the Company from 1993 to August 1994; Director of Great Lakes
 REIT, Inc. and Potash Corporation of Saskatchewan (Canada).
</TABLE>
 
  The Board of Directors of the Company held a total of eleven meetings during
the year ended December 31, 1998. Each director attended more than seventy-
five percent (75%) of the meetings of the Board of Directors (and the Board
committees of which he or she was a member) held during the time he or she was
a member of the Board.
 
                                       2
<PAGE>
 
  The Company currently has Compensation and Audit Committees of the Board of
Directors. The Company does not have a Nominating Committee of the Board of
Directors. The current membership of each committee is as follows:
 
<TABLE>
   <S>                                            <C>
   Compensation Committee                         Audit Committee
   M. Blake Ingle, Ph.D., Chairman                Patrick Owen Burns
   Joseph Klein III                               James C. DeCesare, Chairman
   Donald E. Phillips                             Brenda D. Gavin, DVM
</TABLE>
 
  The function of the Compensation Committee is to review the Company's
compensation policies and advise as to executive compensation and stock option
matters. The Audit Committee oversees the Company's accounting and financial
reporting policies, reviews with the independent accountants the accounting
principles and practices followed, reviews the annual audit and financial
results and makes recommendations to the Board regarding any of the preceding.
The Audit Committee met three times and the Compensation Committee met four
times during the year ended December 31, 1998.
 
  Dr. Ingle became an executive officer of Telios Pharmaceuticals, Inc. in
December 1994, shortly after that company's primary product failed a clinical
trial. In January 1995, Telios filed a voluntary bankruptcy petition. Telios
subsequently emerged from bankruptcy via the sale of the company to Integra
Life Sciences. The Company believes these facts do not impugn Dr. Ingle's
ability or integrity in any way.
 
  For their services as directors, each of the outside directors of the
Company receives fees of $1,000, plus $500 for travel, for each Board of
Directors meeting attended, except for Dr. Gavin. Dr. Gavin does not receive a
fee as S. R. One, Limited does not allow its representatives to accept
director fees from the companies for which they serve as directors. Outside
directors also receive $500 for each telephonic Board of Directors meeting,
and receive $500 for each committee meeting they attend as committee members
which are held on a different day than a Board of Directors meeting. Employee
directors do not receive any fees for attendance at meetings of the Board of
Directors or committee meetings. In addition, Mr. Phillips was paid fees of
$24,996 during the year ended December 31, 1998 pursuant to a consulting
agreement with the Company. On July 30, 1998, pursuant to the Automatic Grant
Program under the 1995 Stock Option/Stock Issuance Plan (the "1995 Plan"), Mr.
Burns, Mr. DeCesare, Dr. Gavin, Dr. Ingle and Mr. Phillips were each granted
options to purchase 7,000 shares of common stock at $3.063 per share. The
options, which expire on July 30, 2008, vest ratably over a one-year period
following the grant date. On September 4, 1998, pursuant to the Automatic
Grant Program under the 1995 Plan, Mr. Klein was granted an option to purchase
7,000 shares of common stock at $2.500 per share. The option, which expires on
September 24, 2008, vests ratably over a one-year period following the grant
date.
 
                                       3
<PAGE>
 
Executive Officers and Significant Employees
 
                               Executive Officers
 
<TABLE>
<CAPTION>
                                                  Name, Age, and Other Business Experience
                   Position                              During the Past Five Years
                   --------                    ---------------------------------------------
<S>                                            <C>
President and Chief Executive Officer - since  Kenneth M. Cohen (44)
 May 1996                                       Formerly, Executive Vice President and Chief
                                                Operating Officer of Canji, Inc., March
                                                1995 -February 1996; Vice President of Argus
                                                Pharmaceuticals, Inc., May 1990 - March 1995
 
Vice President - Finance, Chief Financial      Michael K. Green (43)
 Officer and Secretary - since May 1991
 
Vice President - since February 1998;          Francois Guillemin (48)
 President                                      Formerly, Director of the Diagnostics
 and Director General of Synbiotics Europe,     Division of Rhone-Merieux, S.A., 1991 - June
 SAS - since July 1997                          1997
 
Vice President - Research and Development      Serge Leterme (39)
 since October 1998; Director of Product        Formerly, Director of Research and
 Development - August 1997 - September 1998     Development of the Diagnostics Division of
                                                Rhone-Merieux, S.A., 1993 - June 1997
 
Vice President and General Manager, Animal     Paul A. Rosinack (52)
 Health - since October 1996                    Formerly, President and Chief Executive
                                                Officer of International Canine Genetics,
                                                Inc., December
                                                1992 - October 1996
</TABLE>
 
                             Significant Employees
 
<TABLE>
<CAPTION>
                                                  Name, Age, and Other Business Experience
                   Position                              During the Past Five Years
                   --------                    ---------------------------------------------
<S>                                            <C>
Corporate Controller - since March 1991        Keith A. Butler (37)
 
Director of Operations - since September 1992  Clifford Frank (49)
 
Director of Marketing - since October 1996     Stephen T. Peterson, DVM (48)
                                                Formerly, Director of Marketing of
                                                International Canine Genetics, Inc.,
                                                December 1993 - October 1996
 
Director of Business Development - since 1992  Gregory A. Soulds (52)
 (with the Company since 1983)
</TABLE>
 
                                       4
<PAGE>
 
                             SECURITY OWNERSHIP OF
                   CERTAIN BENEFICIAL OWNERS AND MANAGEMENT
 
  The following table sets forth the beneficial ownership of the Company's
common stock as of April 16, 1999, of each of the Company's directors,
director nominees, 5% shareholders and the Named Executive Officers, and of
the directors and executive officers of the Company as a group. Except as
noted, each person has sole investment and voting power over the shares shown.
Percentages are calculated in accordance with the method set forth in the
Securities and Exchange Commission's rules.
 
<TABLE>
<CAPTION>
                                                          Amount and
                                                          Nature of     Percent
         Name and Address of Beneficial Owner          Beneficial Owner of Class
         ------------------------------------          ---------------- --------
<S>                                                    <C>              <C>
Patrick Owen Burns(/1/)...............................      34,850           *
 22 Sidney Place
 Brooklyn, NY 11201
 
Kenneth M. Cohen(/1/).................................     222,281         2.3%
 c/o Synbiotics Corporation
 11011 Via Frontera
 San Diego, CA 92127
 
James C. DeCesare(/1/)................................      50,125           *
 5260 S. Landings Drive, #200
 Ft. Myers, FL 33919
 
Brenda D. Gavin, DVM(/3/).............................     974,902        10.2%
 c/o S. R. One, Limited
 Bay Colony Executive Park
 565 Swedesford Road
 Suite 315
 Wayne, PA 19087
 
Michael K. Green(/1/).................................      96,655         1.0%
 c/o Synbiotics Corporation
 11011 Via Frontera
 San Diego, CA 92127
 
Francois Guillemin(/1/)...............................      48,512           *
 c/o Synbiotics Europe, SAS
 2 rue Alexander Fleming
 69367 Lyons, Cedex 07, France
 
M. Blake Ingle, Ph.D.(/1/)............................      55,750           *
 Plaza Del Mar 300-6
 12526 High Bluff Drive
 San Diego, CA 92130
 
Joseph Klein III(/1/).................................      25,250           *
 1724 Hillside Road
 Stevenson, MD 21153
 
Serge Leterme, Ph.D.(/1/).............................      18,375           *
 c/o Synbiotics Corporation
 11011 Via Frontera
 San Diego, CA 92127
 
Donald E. Phillips(/1/)...............................      69,750           *
 372 Fannin Landing Circle
 Brandon, MS 39042
</TABLE>
 
                                       5
<PAGE>
 
<TABLE>
<CAPTION>
                                                        Amount and
                                                        Nature of     Percent
        Name and Address of Beneficial Owner         Beneficial Owner of Class
        ------------------------------------         ---------------- --------
<S>                                                  <C>              <C>
Paul A. Rosinack(/1/)...............................       72,961          *
 c/o Synbiotics Corporation
 11011 Via Frontera
 San Diego, CA 92127
 
Gregory A. Soulds(/1/)(/4/).........................       27,781          *
 c/o Synbiotics Corporation
 11011 Via Frontera
 San Diego, CA 92127
 
Gruber & McBaine Capital Management(/2/)............    1,100,100       11.6%
 c/o John P. Broadhurst, Esq.
 Shartsis, Friese & Ginsburg
 One Maritime Plaza
 18th Floor
 San Francisco, CA 94111
 
Merial SAS..........................................      621,378        6.5%
 29 Avenue Tony Garnier
 69007 Lyons
 France
 
S. R. One, Limited(/3/).............................      962,652       10.1%
 Bay Colony Executive Park
 565 Swedesford Road
 Suite 315
 Wayne, PA 19087
 
All executive officers and directors as a
 group(/1/)(/3/) (11 persons).......................    1,697,202       17.8%
</TABLE>
- --------
 *  Less than one percent.
 
(1) Includes options to purchase shares of common stock, which are exercisable
    on or before June 15, 1999, as follows: Mr. Burns - 33,250 shares; Mr.
    Cohen - 155,312 shares; Mr. DeCesare - 40,250 shares; Dr. Gavin - 12,250
    shares; Mr. Green - 88,124 shares; Mr. Guillemin - 26,562; Dr. Ingle -
     31,250 shares; Mr. Klein - 5,250; Dr. Leterme - 15,000; Mr. Phillips -
     59,750 shares; Mr. Rosinack - 60,827 shares; Mr. Soulds - 20,187 shares.
 
(2) 485,400 shares are owned by a group of managed investment accounts who
    have granted their respective powers of attorney to Gruber & McBaine
    Capital Management LLC ("GMCM") to handle any and all necessary filings
    with respect to voting and dispositive power of these securities. The
    remaining 614,700 shares are owned by a group of four persons who granted
    their respective powers of attorney to GMCM to handle any and all
    necessary filings with respect to voting and dispositive power of these
    securities. The direct ownership of these 614,700 shares is as follows:
    Jon D. Gruber ("Gruber") - 91,900 shares; J. Patterson McBaine
    ("McBaine") - 99,200 shares; Lagunitas Partners, a California Limited
    Partnership ("Lagunitas") - 232,500 shares; Proactive Partners, a
    California Limited Partnership ("Proactive") - 191,100 shares. Gruber and
    McBaine are the member managers of GMCM. GMCM is the general partner of
    Lagunitas. Gruber and McBaine are general partners in the entity which is
    the general partner of Proactive. Gruber and McBaine disclaim beneficial
    ownership of the shares held by Lagunitas and Proactive except to the
    extent of their respective pecuniary interests. GMCM disclaims beneficial
    ownership of the shares held by Gruber, McBaine, Lagunitas and the group
    of managed investment accounts.
 
(3) Includes 962,652 shares owned by S. R. One, Limited, of which Dr. Gavin is
    a Vice President. Dr. Gavin disclaims any beneficial ownership of these
    shares.
 
(4) Mr. Soulds' information is included in the interest of full disclosure.
 
 
                                       6
<PAGE>
 
                 EXECUTIVE COMPENSATION AND OTHER INFORMATION
 
  The following table provides certain summary information concerning the
compensation earned by the Company's President and Chief Executive Officer and
the other executive officers whose total 1998 salary and bonus exceeded
$100,000 (the "Named Executive Officers"), and the only other person, although
not an executive officer, whose total 1998 salary and bonus exceeded $100,000
for services rendered in all capacities to the Company for the fiscal years
ended December 31, 1998, 1997 and 1996:
 
                          Summary Compensation Table
 
<TABLE>
<CAPTION>
                                                                               Long-Term
                                     Annual Compensation                     Compensations
                         -----------------------------------------------     -------------
                                                                                Awards
                                                                             -------------
                                                                Other         Securities
                                                                Annual        Underlying      All Other
   Name and Principal    Fiscal                                Compen-         Options/        Compen-
        Position          Year  Salary ($)(/1/) Bonus ($)     sation ($)       SARS (#)    sation ($)(/2/)
   ------------------    ------ --------------- ---------     ----------     ------------- ---------------
<S>                      <C>    <C>             <C>           <C>            <C>           <C>
Kenneth M. Cohen........  1998     $242,156      $31,008(/3/)      --            50,000        $4,115
President and Chief
 Executive Officer        1997     $230,625      $14,175(/4/)      --            25,000        $3,165
                          1996     $141,490      $42,188       $38,750(/5/)     225,000           --
 
Michael K. Green........  1998     $143,500      $18,375(/3/)      --            25,000        $3,875
Vice President            1997     $130,000      $ 8,400(/4/)      --            25,000        $3,120
                          1996     $115,326      $24,000           --            30,000        $2,768
 
Francois Guillemin......  1998     $146,846      $ 7,385(/3/)      --            25,000           --
Vice President            1997     $ 77,744          --            --            50,000           --
 
Serge Leterme...........  1998     $100,489      $15,000(/3/)  $ 4,687(/6/)      25,000           --
Vice President            1997     $ 36,357          --            --            20,000           --
 
Paul A. Rosinack........  1998     $168,373      $21,560(/3/)  $12,504(/7/)      25,000        $2,552
Vice President            1997     $162,129      $ 9,856(/4/)  $12,504(/7/)      50,000           --
                          1996     $ 29,743          --        $ 2,084(/7/)      25,000           --
 
Gregory A. Soulds.......  1998     $112,349      $14,387(/3/)      --               --         $3,033
Director - Business       1997     $106,999      $ 6,576(/4/)      --               --         $2,568
Development               1996     $104,389          --            --             5,000        $2,505
</TABLE>
- --------
(1) Includes amounts deferred under the 401(k) Compensation Deferral Savings
    Plan pursuant to Section 401(k) of the Internal Revenue Code of 1986, as
    amended.
 
(2) Consists of matching contributions made by the Company to Mr. Cohen's
    401(k) account, Mr. Green's 401(k) account, Mr. Rosinack's 401(k) account
    and Mr. Soulds' 401(k) account.
 
(3) Includes grants of restricted Synbiotics common stock during 1998 with a
    fair market value of $4.00 per share as follows: Mr. Cohen - 6,977 shares;
    Mr. Green - 4,134 shares; Mr. Guillemin - 1,662 shares; Dr. Leterme -
     3,375; Mr. Rosinack - 4,851 shares; Mr. Soulds - 3,237 shares.
 
(4) Includes grants of restricted Synbiotics common stock during 1997 with a
    fair market value of $3.19 per share as follows: Mr. Cohen - 4,002 shares;
    Mr. Green - 2,372 shares; Mr. Rosinack - 2,783 shares; Mr. Soulds - 1,857
    shares.
 
(5) Consists of a direct grant of 10,000 shares of Synbiotics common stock
    with a fair market value of $3.875 per share.
 
(6) Forgiveness of a loan made to Dr. Leterme to defray relocation expenses at
    the rate of $18,750 per year. As of December 31, 1998, the balance due was
    $70,313.
 
(7) Forgiveness of a loan made to Mr. Rosinack to defray relocation expenses
    at the rate of $12,504 per year. As of December 31, 1998, the balance due
    was $21,871.
 
                                       7
<PAGE>
 
  The following table contains information concerning the grant of stock
options to the Named Executive Officers:
 
                     Option/SAR Grants in Last Fiscal Year
 
<TABLE>
<CAPTION>
                            Individual Grants
- --------------------------------------------------------------------------
                     Number of
                     Securities   % of Total
                     Underlying  Options/SARs
                    Options/SARs  Granted to
                      Granted    Employees in   Exercise
       Name           (#)(/1/)   Fiscal Year  Price ($/Sh) Expiration Date
       ----         ------------ ------------ ------------ ---------------
<S>                 <C>          <C>          <C>          <C>
Kenneth M. Cohen       50,000       16.71%       $3.06         7/30/08
Michael K. Green       25,000        8.35%       $3.06         7/30/08
Francois Guillemin     25,000        8.35%       $3.06         7/30/08
Serge Leterme          25,000        8.35%       $3.06         5/20/08
Paul A. Rosinack       25,000        8.35%       $3.06         7/30/08
</TABLE>
- --------
(1) The options become exercisable ratably over a four-year period following
    the date of grant, which was July 30, 1998, except for Dr. Leterme whose
    date of grant was May 20, 1998. Each option has a maximum term of 10
    years, subject to earlier termination in the event of the optionee's
    cessation of service with the Company.
 
  The following table provides information, with respect to the Named
Executive Officers and Mr. Soulds, concerning the exercise of options during
the last fiscal year and unexercised options held as of the end of the fiscal
year:
 
              Aggregated Option/SAR Exercises in Last Fiscal Year
                     and Fiscal Year-End Option/SAR Values
 
<TABLE>
<CAPTION>
                                                  Number of Securities      Value of
                                                       Underlying         Unexercised
                                                      Unexercised         In-the-Money
                                                    Options/SARS at     Options/SARS at
                             Shares                December 31, 1998   December 31, 1998
                            Acquired      Value       Exercisable/        Exercisable/
          Name           on Exercise (#) Realized    Unexercisable     Unexercisable(/1/)
          ----           --------------  -------- -------------------- ------------------
<S>                      <C>             <C>      <C>                  <C>
Kenneth M. Cohen........       --           --          100,937             $   --
                                                        199,063             $   --
 
Michael K. Green........       --           --           78,124             $   --
                                                         51,876             $   --
 
Francois Guillemin......       --           --           17,187             $   --
                                                         57,813             $   --
 
Serge Leterme...........       --           --            9,375             $   --
                                                         35,625             $   --
 
Paul A. Rosinack........       --           --           44,600             $   --
                                                         85,227             $   --
 
Gregory A. Soulds.......     2,500         $188          20,375             $   --
                                                          1,875             $   --
</TABLE>
- --------
(1) Value is defined as market price of the Company's common stock at fiscal
    year end less exercise price. The closing sale price of the Company's
    common stock at December 31, 1998 was $2.56.
 
  The Company has not granted any stock appreciation rights ("SARs").
 
 
                                       8
<PAGE>
 
Employment Contracts and Change-in-Control Arrangements
 
  Synbiotics entered into an Employment Agreement dated May 7, 1996 with
Kenneth M. Cohen, its Chief Executive Officer and President. The Employment
Agreement provides for salary at an initial rate of $225,000 per annum,
options to purchase 225,000 shares of Synbiotics common stock (at $3.875 per
share) and a direct grant of 10,000 shares of unregistered Synbiotics common
stock. In addition, he is eligible for a cash bonus of up to 30% of his annual
salary. If Mr. Cohen is terminated without cause, he will receive six months'
salary at his then base salary rate. If Mr. Cohen is terminated in connection
with an acquisition of the Company, he will receive an additional six months'
salary and all unvested stock options will immediately vest.
 
  Synbiotics entered into an Employment Agreement dated June 23, 1997 with
Michael K. Green, its Chief Financial Officer and Vice President - Finance.
The Employment Agreement provides for salary at an initial rate of $140,000.
If Mr. Green is terminated without cause, he will receive six months' salary
at his then base salary rate. If Mr. Green is terminated in connection with an
acquisition of the Company, he will receive an additional six months' salary
and all unvested stock options will immediately vest.
 
  Synbiotics entered into an Employment Agreement dated July 9, 1997 with
Francois Guillemin, its Vice President and President and Director General of
Synbiotics Europe, SAS. The Employment Agreement provides for salary at an
initial rate of $140,000 per annum and options to purchase 50,000 shares of
Synbiotics common stock (at $3.6875 per share). In addition, the Company has
provided Mr. Guillemin with a company car, and is bearing the leasing costs,
and reasonable expenses incurred by Mr. Guillemin for business activities, of
the company car in an annual amount up to $11,500 per year. If Mr. Guillemin
is terminated without cause, he will receive six months' salary at his then
base salary rate plus the amount of legal severance in France; provided,
however, that the total amount to be received will be equal to the greater of
12 months' salary or the total amount of legal severance in France. If Mr.
Guillemin is terminated in connection with an acquisition of the Company, he
will receive an additional six months' salary and all unvested stock options
will immediately vest.
 
  Synbiotics entered into an Employment Agreement dated September 1, 1998 with
Serge Leterme, its Vice President of Research and Development. The Employment
Agreement provides for salary at an initial rate of $120,000. If Dr. Leterme
is terminated without cause, he will receive six months' salary at his then
base salary rate. If Dr. Leterme is terminated in connection with an
acquisition of the Company, he will receive an additional six months' salary
and all unvested stock options will immediately vest.
 
  Synbiotics entered into an Employment Agreement dated October 25, 1996 with
Paul A. Rosinack, its Vice President and General Manager, Animal Health. The
Employment Agreement provides for salary at an initial rate of $160,000 per
annum and options to purchase 25,000 shares of Synbiotics common stock (at
$4.125 per share). If Mr. Rosinack is terminated without cause, he will
receive six months' salary at his then base salary rate. If Mr. Rosinack is
terminated in connection with an acquisition of the Company, he will receive
an additional six months' salary and all unvested stock options will
immediately vest.
 
  THE BOARD OF DIRECTORS RECOMMENDS THE ELECTION OF ALL SEVEN NOMINEES, SET
FORTH IN ITEM 1 ON THE PROXY CARD. The six persons receiving the highest
number of votes will be elected as directors. Abstentions and broker non-votes
will have no influence in the election of directors.
 
                                       9
<PAGE>
 
              AMENDMENT OF 1995 STOCK OPTION/STOCK ISSUANCE PLAN
                          (Item 2 on the Proxy Card)
 
  On April 27, 1995, the Board of Directors adopted the Company's 1995 Stock
Option/Stock Issuance Plan (the "1995 Plan"). The 1995 Plan is intended to
unify the Company's stock option program; upon shareholder approval of the
1995 Plan all outstanding options under the Company's 1983, 1984, 1986, 1987,
1988, 1991 and 1994 Stock Option Plans (the "Prior Plans") were incorporated
into the 1995 Plan and the Prior Plans were terminated as to any future
grants. (The 1983, 1984, 1986, 1987 and 1988 Stock Option Plans have already
expired by their own terms.) The 1,300,000 shares of Company common stock
authorized for issuance under the 1995 Plan were 282,055 more than the sum of
the 711,862 shares currently the subject of options outstanding as of April
27, 1995 under the Prior Plans and 306,083 shares reserved and available for
issuance under, but not as of April 27, 1995 the subject of any grants under,
the Prior Plans.
 
  The 1995 Plan also differed from the Prior Plans in that it (a) allows the
grant of both incentive stock options and non-qualified stock options, (b)
provides for automatic stock option grants to Directors, (c) allows direct
stock issuances, and (d) provides for acceleration of vesting upon a hostile
takeover of the Company. The 1995 Plan also differed from one or more of the
Prior Plans in several other ways, many of which involve providing flexibility
to the Company in areas where the Prior Plans did not allow flexibility.
 
  On April 25, 1997, the Board of Directors approved amendments to the 1995
Plan to incorporate the 1996 Stock Option Plan into the 1995 Plan, add an
additional 450,000 shares to the maximum authorized for issuance under the
1995 Plan (making a total, together with the previous authorization and the
250,000 shares authorized under the 1996 Stock Option Plan, of 2,000,000
shares), provide for additional flexibility as permitted under recent changes
to Rule 16b-3 under the Securities Exchange Act of 1934, and make certain non-
material changes in other areas.
 
  The 1996 Stock Option Plan authorized only the grant of nonstatutory
options, and only to persons who are not directors or officers. Otherwise, the
1996 Stock Option Plan is essentially similar to the 1995 Plan's Discretionary
Grant Program.
 
  On March 29, 1999, the Board of Directors approved an amendment (the
"Amendment") to the 1995 Plan to incorporate the 1998 Stock Option Plan into
the 1995 Plan and add an additional 600,000 shares to the maximum authorized
for issuance under the 1995 Plan (making a total, together with the previous
amended authorization and including the 152,565 shares authorized under the
1998 Stock Option Plan, of 2,752,565 shares).
 
  The 1998 Stock Option Plan authorizes only the grant of nonstatutory
options, and only to persons who are not directors or officers. In addition,
the 1998 Stock Option Plan gives the Plan Administrator complete discretion in
establishing the options' exercise price per share. Otherwise, the 1998 Stock
Option Plan is essentially similar to the 1995 Plan's Discretionary Grant
Program. Options to purchase all 152,565 of the 1998 Stock Option Plan's
authorized shares were granted to former optionholders of Prisma Acquisition
Corp. ("Prisma") in exchange for their Prisma Options, pursuant to the terms
of Synbiotics' March 1998 acquisition of Prisma. As of April 16, 1999, options
to purchase 10,613 shares under the 1998 Stock Option Plan have been
exercised, and the remaining options to purchase 141,952 are still
outstanding.
 
  Synbiotics currently has available under the 1995 Plan only 49,516 shares
which have not already been issued and are not subject to currently
outstanding options. Of those shares, 42,000 will be subjected to options to
non-employee directors on June 9, 1999. Therefore, unless the Amendment is
approved Synbiotics will essentially have run out of shares for option grants
and direct issuances.
 
  There are currently outstanding under the 1995 Plan and the 1998 Stock
Option Plan options to purchase a total of 1,956,737 shares, and with the
additional 600,000 shares requested by the Amendment, a total of 2,556,737
will be potentially exercisable.
 
  Under the 1995 Plan, the Amendment requires shareholder approval to become
effective.
 
 
                                      10
<PAGE>
 
Plan Structure
 
  The 1995 Plan is divided into three separate parts:
 
 .  The "Discretionary Grant Program" under which directors, employees and
   consultants may, at the discretion of the Plan Administrator, be granted
   options to purchase shares of the Common Stock at an exercise price not less
   than 85% of the fair market value of each such share on the grant date;
   provided, that the exercise price may be below 85% of fair market value if
   the optionee makes a payment to the Company (including payment made by means
   of a salary reduction agreement) of no less than the excess (above 15%) of
   the discount from fair market value exercise price. The granted options may
   be either incentive stock options which are designed to meet the
   requirements of Section 422 of the Internal Revenue Code or nonstatutory
   options not intended to satisfy such requirements.
 
 .  The "Stock Issuance Program" under which eligible individuals will be
   allowed to effect immediate purchases of Common Stock at the fair market
   value of each such share, or at discounts of up to 15% (or, under certain
   conditions, more) from the fair market value of any such share, including
   shares which may be issued in consideration for past services without any
   cash payment required of the participant.
 
 .  The "Automatic Grant Program," under which an option grant will be made to
   each individual upon first joining the Board of Directors as a nonemployee
   member and subsequent annual automatic option grants will be made to each
   individual who is re-elected as a nonemployee director of Synbiotics.
 
  As of March 31, 1999, approximately 135 officers and employees were eligible
to participate in the Discretionary Grant Program and the Stock Issuance
Program. There are currently six nonemployee directors standing for re-election
who will be eligible to receive automatic grants under the Automatic Grant
Program.
 
Plan Administration
 
  Option grants under the Discretionary Grant Program and stock issuances under
the Stock Issuance Program are to be made by the Board or by a committee of two
or more nonemployee Board members or, as to discretionary option grants to any
person other than directors, officers or 10% stockholders, by a committee of
any two or more directors (the "Plan Administrator"). The selected committee
members serve for such period of time as the Board may determine and will be
subject to removal by the Board at any time.
 
  The Plan Administrator has the sole and exclusive authority, subject to the
provisions of the 1995 Plan, to determine the eligible individuals who are to
receive options under the Discretionary Grant Program or the Stock Issuance
Program, the number of shares to be covered by each granted option or issuance,
the date or dates on which the option is to become exercisable and the maximum
term for which the option is to remain outstanding. The Plan Administrator has
the authority to determine whether the granted option is to be an incentive
stock option ("Incentive Option") under the Federal tax laws and to establish
rules and regulations for proper plan administration. Options grants under the
Automatic Grant Program are made in strict compliance with the express
provisions of that program, and the Plan Administrator does not have any
discretionary authority with respect to those option grants.
 
Effect on Prior Plans
 
  The 1995 Plan replaced and serves as the successor to the Prior Plans and the
1996 Stock Option Plan (the "Expanded Prior Plans"). No further option grants
will be made under the Expanded Prior Plans and all options outstanding under
the Expanded Prior Plans have been incorporated into the 1995 Plan and treated
as outstanding options under the 1995 Plan. However, each outstanding option so
incorporated shall continue to be governed solely by the terms of the documents
evidencing such option. No provision of the 1995 Plan adversely affects or
diminishes the rights or obligations of the optionees of the incorporated
options. Subject to the rights of the optionee under the incorporated option
documents, the Plan Administrator's discretion under the 1995 Plan may be
exercised with respect to incorporated options to the same extent as it is
exercisable with respect to options originally granted under the 1995 Plan.
 
                                       11
<PAGE>
 
  The Amendment would make the 1998 Stock Option Plan an Expanded Prior Plan.
 
Issuable Shares
 
  The maximum number of shares of Common Stock reserved for issuance over the
10 year term of the 1995 Plan, measured from the Effective Date of the 1995
Plan can not exceed 2,000,000 shares. The Amendment would increase that maximum
number to 2,752,565. Such authorized share reserve is comprised of (i) the
number of shares that remained available for issuance under the Expanded Prior
Plans, including the shares subject to the outstanding options incorporated
into the 1995 Plan and any other shares that would have been available for
future option grant or share issuance under the Expanded Prior Plans, and (ii)
an additional 600,000 shares (which would become a total of 1,332,055 shares if
the Amendment is approved). The share reserve available for issuance under the
1995 Plan will be subject to periodic adjustment for changes in Synbiotics'
Common Stock occasioned by stock splits, stock dividends, recapitalizations,
conversions or other changes affecting the outstanding Common Stock as a class
without Synbiotics' receipt of consideration. To the extent any of the
incorporated options are subsequently exercised, the number of shares issued
under those options will reduce, on a share-for-share basis, the number of
shares available for issuance under the 1995 Plan.
 
  Should an option expire or terminate for any reason prior to exercise in full
(including options canceled in accordance with the cancellation-regrant
provisions described below), the shares subject to the portion of the option
not so exercised will be available for subsequent option grants or share
issuances under the 1995 Plan. All shares issued under the 1995 Plan, whether
or not such shares are subsequently reacquired by Synbiotics pursuant to its
repurchase rights under the 1995 Plan, will reduce on a share-for-share basis
the number of shares of Common Stock available for subsequent grants.
 
  No more than 800,000 shares may be granted to any one optionee over the
lifetime of the 1995 Plan.
 
Terms of Discretionary Grant Program
 
  Option Price and Term. No option will have a term in excess of 10 years
measured from the grant date. The option price per share for incentive stock
options will not be less than 100% of the fair market value of each share of
Synbiotics Common Stock issuable under the option on the grant date of such
option. The option price per share for nonstatutory stock options may not be
less than 85% of the fair market value per share of each share of Synbiotics
Common Stock issuable under the option on the grant date of such option;
provided, that nonstatutory options may be granted having an exercise price
below 85% of fair market value if the optionee makes a payment to the Company
(including payment made by means of a salary reduction agreement) of no less
than the excess (above 15%) of the discount from fair market value exercise
price.
 
  Valuation. For purposes of establishing the option exercise price for
Synbiotics Common Stock, the "Fair Market Value" per share of the stock on any
relevant date will be the closing selling price per share on such date, as
quoted on the Nasdaq National Market. If there is no reported selling price for
such date, then the closing selling price for the last previous date for which
such quotation exists will be determinative of Fair Market Value.
 
  Vesting of Options. The vesting schedule for each granted option will be
determined by the Plan Administrator and will be set forth in the instrument
evidencing such grant. The granted option may be (i) immediately exercisable
for vested shares, (ii) immediately exercisable for unvested shares subject to
Synbiotics' repurchase rights or (iii) exercisable in installments for vested
shares over the optionee's period of service.
 
  Payment. Upon exercise of the option, the option price for the purchased
shares will become immediately payable in cash or in shares of common stock
valued at fair market value on the date of exercise. The option my also be
exercised through a cashless exercise procedure pursuant to which the optionee
provides irrevocable written instructions to a designated brokerage firm to
effect the immediate sale of the purchased shares and remit to Synbiotics, out
of the said proceeds, an amount equal to the aggregate option price payable for
the purchased
 
                                       12
<PAGE>
 
shares plus all applicable withholding taxes. The Plan Administrator may assist
any optionee (including a director or an officer) in the exercise of one or
more outstanding options under the 1995 Plan by (i) authorizing a loan from
Synbiotics or (ii) permitting the optionee to pay the option price in
installments over a period of years. The term and conditions of any such loan
or installment payment will be established by the Plan Administrator in its
sole discretion, but in no event will the maximum credit extended to the
optionee exceed the aggregate option price for the purchased shares plus any
Federal or State tax liability incurred in connection with the option exercise.
 
  Termination of Service. Should the optionee cease to remain in Synbiotics'
service while holding one or more options under the 1995 Plan, then those
options will not remain exercisable beyond the limited post-service period
designated by the Plan Administrator at the time of the option grant (subject
to certain minimum post-service periods). Under no circumstances, however, may
any option be exercised after the specified expiration date of the option term.
Each such option will, during the period it remains exercisable, be exercisable
for the number of shares for which the option was exercisable on the date of
the optionee's cessation of service.
 
  Should the optionee die while holding one or more outstanding options, then
the personal representative of the optionee's estate or the person or persons
to whom each such option is transferred pursuant to the optionee's will or in
accordance with the laws of inheritance will have the right to exercise such
option for any or all of the shares for which the option is exercisable on the
date of the optionee's cessation of service, less any option shares
subsequently purchased by the optionee prior to death. Such right will lapse,
and the option will terminate, upon the earlier of (i) the end of the limited
post-service period designated by the Plan Administrator at the time of the
option grant or (ii) the specified expiration date of the option term.
 
  The Plan Administrator will have complete discretion to extend the period
following the optionee's termination of service during which his or her
outstanding options may be exercised and/or to accelerate the exercisability of
such options in whole or in part. Such discretion may be exercised at any time
while the options remain outstanding, whether before or after the optionee's
actual cessation of service.
 
  Corporate Transaction. Except to the extent otherwise provided in the option
documents, each option share will become fully vested in the event of certain
Corporate Transactions unless the option is assumed or is replaced with a cash
incentive program which preserves the material benefits of the options. Upon
consummation of the Corporate Transaction all options which are not assumed
will be canceled and cease to exist. The options or cash incentive programs
which replace any options which do not accelerate will provide for full vesting
in the event of involuntary termination of employment within 18 months
following the Corporate Transaction.
 
  For purposes of the above, a Corporate Transaction includes (i) a merger or
consolidation in which Synbiotics is not the surviving entity (except for a
transaction the principal purpose of which is to change the State of
incorporation), (ii) the sale, transfer or other disposition of all or
substantially all of the assets of Synbiotics, or (iii) any reverse merger in
which Synbiotics is the surviving entity but in which securities possessing
more than fifty percent (50%) of the total combined voting power of Synbiotics
are transferred to holders different from those who held Synbiotics' securities
immediately prior to such merger.
 
  Shareholder Rights and Option Assignability. No optionee is to have any
shareholder rights with respect to the option shares until such optionee has
exercised the option, paid the option price for the purchased shares and been
issued a stock certificate for such shares. Unless the Plan Administrator
expressly approves in writing, options are not assignable or transferable other
than by will or by the laws of inheritance following the optionee's death, and
the option may, during the optionee's lifetime, be exercised only by the
optionee.
 
  Cancellation/Regrant. The Plan Administrator has the authority to effect, on
one or more separate occasions, the cancellation of outstanding options under
the Discretionary Grant Program which have exercise prices in excess of the
then current market price of the Common Stock and to issue replacement options
with an exercise price based on the lower market price of the Common Stock at
the time of grant.
 
 
                                       13
<PAGE>
 
Terms of Stock Issuance Program
 
  Issue Price. The purchase price per share will not be less than 85% of the
fair market value of a share of Synbiotics Common Stock on the date the Plan
Administrator authorizes the issuance.
 
  Vesting of shares. The vesting schedule for each share issued will be
determined by the Plan Administrator and set forth in the issuance agreement.
The shares may be fully and immediately vested upon issuance or may vest in one
or more installments, subject to Synbiotics' repurchase right, over the
participant's period of service.
 
  Shareholder Rights. The recipient of the share issuance will have full
shareholder rights, including voting and dividend rights, with respect to the
issued shares, whether or not the shares are vested. However, the recipient may
not sell, transfer or assign any unvested shares issued under the 1995 Plan
except for certain limited family transfers.
 
  Repurchase Rights. Should the recipient of unvested shares cease to remain in
Synbiotics' service before vesting in such shares, then those unvested shares
are to be immediately surrendered to Synbiotics for cancellation, and the
recipient will have no further stockholder rights with respect to those shares.
To the extent the surrendered shares were previously issued to the recipient
for consideration paid in cash or promissory note, Synbiotics will refund the
cash consideration paid for the surrendered shares and cancel the principal
balance of the note to the extent attributable to such surrendered shares.
 
  Payment. Upon issuance of the shares, the issue price for the purchased
shares will become immediately payable in cash or (upon Plan Administrator
approval) by promissory note payable to Synbiotics' order. The promissory note
may, at the discretion of the Plan Administrator, be subject to cancellation
over the participant's period of service. Shares may also be issued for past
services, without any cash or other payment required of the participant.
 
  Corporate Transaction. Except to the extent otherwise provided in the stock
issuance documents, all repurchase rights will terminate and each share will
become fully vested in the event of a Corporate Transaction (as defined above)
unless the repurchase rights are assigned to the successor corporation.
Following consummation of the Corporate Transaction, all repurchase rights
which are not assigned to the successor will terminate and cease to exist. The
assigned purchase rights will terminate and cease to exist in the event of
involuntary termination of employment within 18 months following the Corporate
Transaction.
 
Terms of Automatic Grant Program
 
  Each individual who first becomes a nonemployee Board member, whether through
election by the stockholders or appointment by the Synbiotics Board, and who
was not otherwise in the prior employ of Synbiotics is automatically granted,
at the time of such initial election or appointment, a non-statutory stock
option to purchase 7,000 shares of Synbiotics Common Stock. Further, at each
annual Stockholders Meeting, each individual who is at that time reelected as a
nonemployee Board member is automatically granted a nonstatutory stock option
under the Automatic Grant Program to purchase an additional 7,000 shares of
Synbiotics Common Stock. There is no limit on the number of such 7,000-share
option grants the nonemployee Synbiotics Board member may receive over his or
her period of Board service.
 
  Each such option grant is subject to the following terms and conditions:
 
<TABLE>
 <C>   <S>
 (i)   The option price per share is equal to 100% of the Fair Market Value per
       share of Common Stock on the grant date.
 
 (ii)  Each option has a term of 10 years measured from the grant date.
 
 (iii) Each automatic grant is immediately exercisable in full, provided that
       any shares issued upon the exercise of an automatic option grant shall
       be subject to repurchase at the option exercise price if the Board
       member ceases to be in service prior to the vesting of such shares.
 
</TABLE>
 
                                       14
<PAGE>
 
<TABLE>
 <C>  <S>
 (iv) The shares vest in four equal quarterly installments over the optionee's
      period of service following the automatic option grant.
 
 (v)  The options remain exercisable during the remainder of their term
      following the optionee's cessation of Synbiotics Board membership for any
      reason, provided that the option shall be exercisable following the
      termination of service only with respect to the shares which were vested
      as of such termination of service date. Should the optionee die while any
      option is still exercisable, then such option may be exercised by the
      personal representative of the optionee's estate or the person to whom
      the grant is transferred by the optionee's will or the laws of
      inheritance.
 
 (vi) The remaining terms and conditions of the option in general conform to
      the terms described above for option grants made under the Discretionary
      Grant Program and are incorporated into the option agreement evidencing
      the automatic grant.
</TABLE>
 
  Each option share will become fully vested in the event of a Corporate
Transaction (as defined above). Upon consummation of the Corporate Transaction,
all options will be canceled and cease to exist.
 
Changes in Capitalization
 
  In the event any change is made to the Common Stock issuable under the 1995
Plan by reason of any recapitalization, stock dividend, stock split,
combination of shares, exchange of shares, or other change in corporate
structure effected without Synbiotics' receipt of consideration, appropriate
adjustments will be made to (i) the maximum number and/or class of securities
issuable under the 1995 Plan, (ii) the number and/or class of securities and
price per share in effect under each outstanding option (including all
discretionary and automatic option grants under the 1995 Plan and all option
grants incorporated from the Expanded Prior Plans), and (iii) the number and/or
class of securities per nonemployee member of the Board for which option grants
will subsequently be made under the Automatic Grant Program.
 
  Each outstanding option which is assumed or is otherwise to continue in
effect after a Corporate Transaction win be appropriately adjusted to apply and
pertain to the number and class of securities which would have been issuable,
in connection with such Corporate Transaction, to an actual holder of the same
number of shares of Synbiotics Common Stock as are subject to such option
immediately prior to such Corporate Transaction. Appropriate adjustments will
also be made to the option price payable per share and to the number and class
of securities available for issuance under the 1995 Plan.
 
  Option grants under the 1995 Plan will not affect the right of Synbiotics to
adjust, reclassify, reorganize or otherwise change its capital or business
structure or to merge, consolidate, dissolve, liquidate or sell or transfer all
or any part of its business or assets.
 
Special Tax Withholding Election
 
  The Plan Administrator may provide one or more participants in the 1995 Plan
with the election to have Synbiotics withhold, from the shares of Common Stock
otherwise issuable upon the exercise of non-qualified options or the vesting of
unvested shares, a portion of those shares in satisfaction of the tax liability
incurred in connection with their acquisition or vesting. Any election so made
will be subject to the approval of the Plan Administrator, and no shares will
be accepted in satisfaction of such tax liability except to the extent the Plan
Administrator approves the election. Alternatively, one or more participants
may be granted the right, subject to Plan Administrator approval, to deliver
existing shares of Common Stock in satisfaction of such tax liability. The
withheld or delivered shares will be valued at their then current fair market
value.
 
Amendment and Termination
 
  The Board of Directors may amend or modify the 1995 Plan in any or all
respects whatsoever. However, no such amendment may adversely affect the rights
of existing optionees without their consent and unless
 
                                       15
<PAGE>
 
otherwise necessary to comply with applicable tax laws and regulations. In
addition, shareholder approval of and amendment or modification of the 1995
Plan must be obtained if it is required by law or regulation or, in a
particular instance, by a Board of Directors decision that shareholder approval
should be required.
 
  The Board may terminate the 1995 Plan at any time, and the 1995 Plan will in
all events terminate on April 25, 2005. Each stock option outstanding at the
time of such termination will remain in force in accordance with the provisions
of the instruments evidencing such grant.
 
Federal Tax Consequences
 
  Options granted under the 1995 Plan may be either incentive stock options
which satisfy the requirements of Section 422 of the Internal Revenue Code or
non-qualified options which are not intended to meet such requirements. The
Federal income tax treatment for the two types of options differs as described
below:
 
  Incentive Options. No taxable income is recognized by the optionee at the
time of the option grant, and no taxable income is generally recognized at the
time the option is exercised. The optionee will, however, recognize income for
alternative minimum tax purposes in the year the option is exercised and
regular taxable income in the year in which the purchased shares are sold or
otherwise made the subject of disposition.
 
  For Federal tax purposes, dispositions are divided into two categories: (i)
qualifying and (ii) disqualifying. The optionee will make a qualifying
disposition of the purchased shares if the sale or other disposition of such
shares is made after the optionee has held the shares for more than two years
after the grant date of the option and more than one year after the exercise
date. If the optionee fails to satisfy either of these two holding periods
prior to the sale or other disposition of the purchased shares, then a
disqualifying disposition will result.
 
  Upon a qualifying disposition of the shares, the optionee will recognize
long-term capital gain in an amount equal to the excess of (i) the amount
realized upon the sale or other disposition of the purchased shares over
(ii) the exercise price paid for such shares. If there is a disqualifying
disposition of the shares, then the excess of (i) the fair market value of
those shares on the date the option was exercised over (ii) the exercise price
paid for the shares will be taxable as ordinary income. Any additional gain
recognized upon the disposition will be a capital gain.
 
  If the optionee makes a disqualifying disposition of the purchased shares,
then Synbiotics will be entitled to an income tax deduction, for the taxable
year in which such disposition occurs, equal to the excess of (i) the fair
market value of such shares on the date the option was exercised over (ii) the
exercise price paid for the shares. In no other instance will Synbiotics be
allowed a deduction with respect to the optionee's disposition of the purchased
shares.
 
  Non-qualified Options. No taxable income is recognized by an optionee upon
the grant of a non-qualified option. The optionee will in general recognize
ordinary income, in the year in which the option is exercised, equal to the
excess of the fair market value of the purchased shares on the date of exercise
over the exercise price paid for the shares, and the optionee will be required
to satisfy the tax withholding requirements applicable to such income.
 
  Special provisions of the Internal Revenue Code apply to the acquisition of
Common Stock under a non-qualified option, if the purchased shares are subject
to repurchase by Synbiotics. These special provisions may be summarized as
follows:
 
A. If the shares acquired upon exercise of the non-qualified option are subject
   to repurchase by Synbiotics at the original exercise price in the event of
   the optionee's termination of service prior to vesting in such shares, the
   optionee will not recognize any taxable income at the time of exercise but
   will have to report as ordinary income, as and when Synbiotics' repurchase
   right lapses, an amount equal to the excess of (i) the fair market value of
   the shares on the date Synbiotics' repurchase right lapses with respect to
   such shares over (ii) the exercise price paid for the shares.
 
                                       16
<PAGE>
 
B. The optionee may, however, elect under Section 83(b) of the Internal Revenue
   Code to include as ordinary income in the year of exercise of the non-
   qualified option an amount equal to the excess of (i) the fair market value
   of the purchased shares on the date of exercise (determined as if the shares
   were not subject to Synbiotics' repurchase right) over (ii) the exercise
   price paid for such shares. If the Section 83(b) election is made, the
   optionee will not recognize any additional income as and when the
   Synbiotics' repurchase right lapses.
 
  Synbiotics will be entitled to a business expense deduction equal to the
amount of ordinary income recognized by the optionee with respect to the
exercised non-qualified option. The deduction will in general be allowed for
the taxable year of Synbiotics in which such ordinary income is recognized by
the optionee.
 
  Direct Stock Issuances. The tax consequences of individuals who receive
direct stock issuances under the 1995 Plan will be substantially the same as
the treatment described above for the exercise of non-qualified stock options.
 
Accounting Treatment
 
  Option grants with exercise prices less than the fair market value of the
option shares on the grant date and direct stock issuances at purchase prices
less than the fair market value of the issued shares will result in a
compensation expense charge to Synbiotics' earnings equal to the difference
between such exercise or purchase prices and the fair market value of the
shares on the option grant date or (for direct stock issuances) the fair market
value on the issue date. Such expense will be accrued by Synbiotics over the
period the optionee or share recipient vests in the option shares or directly-
issued shares. Option grants and direct stock issuances at 100% of fair market
value will not result in any charge to Synbiotics' earnings. Whether or not
granted at a discount, the number of outstanding options may be a factor in
determining Synbiotics' earnings per share.
 
  THE BOARD OF DIRECTORS RECOMMENDS APPROVAL OF THE AMENDMENT TO THE 1995 STOCK
OPTION/STOCK ISSUANCE PLAN (ITEM 2 ON THE PROXY CARD). Approval will require
the affirmative vote of a majority of those shares which are present or
represented at the Meeting. Abstentions will have the same effect as votes
against approval of the Amendment of the 1995 Plan. Broker non-votes will,
assuming the shares are represented at the Meeting for any purpose, have the
same effect as votes against approval of the Amendment of the 1995 Plan; but if
the shares are entirely not represented at the Meeting the broker non-votes
will have no effect on the proposal to approve the Amendment of the 1995 Plan.
 
                      COMPLIANCE WITH SECTION 16(a) OF THE
                        SECURITIES EXCHANGE ACT OF 1934
 
  Section 16(a) of the Securities Exchange Act of 1934 requires the Company's
officers and directors, and persons who own more than 10% of a registered class
of the Company's equity securities, to file reports of ownership and changes in
ownership of the Company's equity securities with the Securities and Exchange
Commission. Officers, directors and greater than 10% shareholders are required
by SEC regulations to furnish the Company with copies of all Section 16(a)
forms they file.
 
  Based solely on its review of the copies of such forms furnished to the
Company, or written representations that no Forms 5 were required, the Company
believes that during the fiscal year ended December 31, 1998, all Section 16(a)
filing requirements applicable to its officers, directors and greater than 10%
beneficial owners were complied with.
 
 
                                       17
<PAGE>
 
                             SHAREHOLDER PROPOSALS
 
  To be included in the Company's proxy materials for the Annual Meeting of
Shareholders to be held in 1999, a shareholder proposal must be received at the
offices of the Company, 11011 Via Frontera, San Diego, CA 92127, not later than
January 7, 2000.
 
                                 OTHER MATTERS
 
  PricewaterhouseCoopers LLP has served as the independent accountants of the
Company for a number of years. Although management anticipates that this
relationship will continue to be maintained during fiscal 1999, as in previous
years, it is not proposed that any formal action be taken at the Annual Meeting
with respect to the continued employment of PricewaterhouseCoopers LLP.
Representatives of PricewaterhouseCoopers LLP are expected to be present at the
Company's Annual Meeting with the opportunity to make a statement if they
desire to do so and they are expected to be available to respond to appropriate
questions.
 
  The Board of Directors, at this time, knows of no other business which will
be presented to the meeting. If any other business is properly brought before
the meeting, it is intended that the proxies in the enclosed form will be voted
in respect thereof in accordance with the judgment of the persons voting the
proxies.
 
  The Company's Annual Report, including the Company's audited financial
statements for the fiscal year ended December 31, 1998, is being mailed
herewith to all shareholders of record. THE COMPANY WILL PROVIDE WITHOUT CHARGE
TO ANY BENEFICIAL OWNER OF COMMON STOCK ON APRIL 16, 1999, UPON THE WRITTEN
REQUEST OF ANY SUCH PERSON, A COPY OF THE COMPANY'S ANNUAL REPORT ON FORM 10-
KSB FOR THE FISCAL YEAR ENDED DECEMBER 31, 1998 FILED WITH THE SECURITIES AND
EXCHANGE COMMISSION. SUCH REQUESTS SHOULD BE DIRECTED TO MICHAEL K. GREEN, VICE
PRESIDENT - FINANCE OF THE COMPANY, AT 11011 VIA FRONTERA, SAN DIEGO, CA 92127.
 
  Whether you intend to be present at this meeting or not, you are urged to
return your proxy promptly.
 
                                          By order of the Board of Directors
 
                                          Michael K. Green
                                          Secretary
 
                                       18
<PAGE>
 
                                                                      APPENDIX A
                                                                      ----------

NOTE: THIS ITEM IS BEING FILED WITH THE COMMISSION PURSUANT TO INSTRUCTION 3 TO
ITEM 10(B) OF SCHEDULE 14A.  THE ITEM IS NOT PART OF THE PROXY STATEMENT AND
WILL NOT BE DISTRIBUTED TO THE COMPANY'S SHAREHOLDERS IN CONJUNCTION WITH THE
SOLICITATION OF PROXIES.


                            SYNBIOTICS CORPORATION
                     1995 STOCK OPTION/STOCK ISSUANCE PLAN
                     -------------------------------------
                       as amended through March 29, 1999
                       ---------------------------------


                                  ARTICLE ONE
                              GENERAL PROVISIONS
                              ------------------

I.   PURPOSE OF THE PLAN

This 1995 Stock Option/Stock Issuance Plan (the "Plan") is intended to promote
the interests of Synbiotics Corporation, a California corporation, by providing
eligible persons with the opportunity to acquire a proprietary interest, or
otherwise increase their proprietary interest, in the Corporation as an
incentive for them to remain in the service of the Corporation.

Capitalized terms not otherwise defined shall have the meanings assigned to such
terms in the attached Appendix.


II.  STRUCTURE OF THE PLAN

     A.   The Plan shall be divided into three separate equity programs:

          (i)   the Discretionary Option Grant Program under which eligible
                persons may, at the discretion of the Plan Administrator, be
                granted options to purchase shares of common stock of the
                Corporation,

          (ii)  the Stock Issuance Program under which eligible persons may, at
                the discretion of the Plan Administrator, be issued shares of
                common stock of the Corporation directly, either through the
                immediate purchase of such shares or as a bonus for services
                rendered the Corporation (or any Parent or Subsidiary), and

          (iii) the Automatic Option Grant Program under which non-employee
                directors shall automatically receive option grants at periodic
                intervals to purchase shares of common stock of the Corporation.

     B.   The provisions of Articles One and Five shall apply to all equity
          programs under the Plan and shall accordingly govern the interests of
          all persons under the Plan.


III. ADMINISTRATION OF THE PLAN

     A.   Plan Administrator.  Either the Board or a committee of two (2) or
          ------------------                                                
          more non-employee Board members appointed by the Board to administer
          the Discretionary Option Grant and Stock Issuance Programs with
          respect to Section 16 insiders (the "Primary Committee") shall have
          sole and exclusive authority to administer the Plan with respect to
          Section 16 Insiders.
<PAGE>
 
     B.   Committees.  Administration of the Discretionary Option Grant and
          ----------
          Stock Issuance Programs with respect to all other persons eligible to
          participate in those programs may, at the Board's discretion, be
          vested in the Board, the Primary Committee or a committee of two (2)
          or more Board members appointed by the Board to administer the
          Discretionary Option Grant Program and Stock Issuance Program with
          respect to eligible persons other than Section 16 insiders (the
          "Secondary Committee"), or the Board may retain the power to
          administer those programs with respect to all such persons. All Board
          members are eligible to be members of the Secondary Committee,
          including Board members who are Employees eligible to receive
          discretionary option grants or direct stock issuances under the Plan
          or any other stock option, stock appreciation, stock bonus or other
          stock plan of the Corporation (or any Parent or Subsidiary).

     C.   Members of Committees.  Members of the Primary Committee or any
          ---------------------                                          
          Secondary Committee shall serve for such period of time as the Board
          may determine and may be removed by the Board at any time.  The Board
          may also at any time terminate the functions of any Secondary
          Committee and assume all powers and authority previously delegated to
          such committee.

     D.   Service as Committee Members.  Service on the Primary Committee or the
          ----------------------------                                          
          Secondary Committee shall constitute service as a Board member, and
          members of each such committee shall accordingly be entitled to full
          indemnification and reimbursement as Board members for their service
          on such committee.  No member of the Primary Committee or the
          Secondary Committee shall be liable for any act or omission made in
          good faith with respect to the Plan or any option grants or stock
          issuances under the Plan.

     E.   Authority.  Each Plan Administrator shall, within the scope of its
          ---------                                                         
          administrative functions under the Plan, have full power and authority
          (subject to the express provisions of the Plan) to (i) establish such
          rules and regulations as it may deem appropriate for the proper
          administration of the Discretionary Option Grant Program and Stock
          Issuance Program and to make such determinations under, and issue such
          interpretations of, such programs and any outstanding option grants or
          stock issuances as it may deem necessary or advisable, (ii) determine,
          with respect to the option grants under the Discretionary Option Grant
          Program, which eligible persons are to receive option grants, the time
          or times when such option grants are to be made, the number of shares
          to be covered by each such grant, the status of the granted option as
          either an Incentive Option or a Non-Statutory Option, the time or
          times at which each option is to become exercisable, the vesting
          schedule (if any) applicable to the option shares and the maximum term
          for which the option is to remain outstanding and (iii) determine,
          with respect to stock issuances under the Stock Issuance Program,
          which eligible persons are to receive stock issuances, the time or
          times when such issuances are to be made, the number of shares to be
          issued to each Participant, the vesting schedule (if any) applicable
          to the issued shares and the consideration to be paid by the
          Participant for such shares.  The Plan Administrator(s) shall have the
          absolute discretion either to grant options in accordance with the
          Discretionary Option Grant Program or to effect stock issuances in
          accordance with the Stock Issuance Program.  Decisions of each Plan
          Administrator shall be final and binding on all parties who have an
          interest in the Discretionary Option Grant Program and Stock Issuance
          Program or any outstanding option or stock issuance thereunder.

     F.   Restriction on Discretion.  The administration of the Automatic Option
          -------------------------                                             
          Grant Program under Article Three shall be self executing in
          accordance with the terms and conditions thereof and the Plan
          Administrator shall not exercise any discretionary functions in
          respect to matters governed by Article Three.

                                      -2-
<PAGE>
 
IV.  OPTION GRANTS AND STOCK ISSUANCES

     A.   Subject to Section V.B below, the persons eligible to receive stock
          issuances under the Stock Issuance Program ("Participant") and/or
          option grants pursuant to the Discretionary Option Grant Program
          ("Optionee") are as follows:

          (i)   officers and other employees of the Corporation (or its parent
                or subsidiary corporations) who render services which contribute
                to the management, growth and financial success of the
                Corporation (or its parent or subsidiary corporations);

          (ii)  non-employee members of the Board; and

          (iii) those consultants or other independent contractors who provide
                valuable services to the Corporation (or its parent or
                subsidiary corporations).

     B.   The individuals eligible to receive option grants under the Automatic
          Option Grant Program shall be those individuals who serve as non-
          employee Board members during the term of the Plan.


V.   STOCK SUBJECT TO THE PLAN

     A.   The stock issuable under the Plan shall be shares of authorized but
          unissued or reacquired common stock of the Corporation ("Common
          Stock"), including shares repurchased by the Corporation on the open
          market.  The maximum number of shares of Common Stock which may be
          issued over the term of the Plan shall not exceed 2,752,565 shares.
          Such authorized share reserve is comprised of (i) the number of shares
          available for issuance under the Predecessor Plan as last approved by
          the Corporation prior to their incorporation into this Plan, including
          the shares subject to the outstanding options incorporated into the
          Plan and any other shares which would have been available for future
          option grants under the Predecessor Plan, plus (ii) an additional
          increase of 1,332,055 shares authorized by the Board under the Plan,
          subject to stockholder approval.

     B.   No one person participating in the Plan may receive options and direct
          stock issuances for more than 800,000 shares of Common Stock in the
          aggregate over the term of the Plan.

     C.   Shares of Common Stock subject to outstanding options shall be
          available for subsequent issuance under the Plan to the extent (i) the
          options (including any options incorporated from the Predecessor
          Plan) expire or terminate for any reason prior to exercise in full or
          (ii) the options are cancelled in accordance with the cancellation-
          regrant provisions of Article Two.  All shares issued under the Plan
          (including shares issued upon exercise of options incorporated from
          the Predecessor Plan), whether or not those shares are subsequently
          repurchased by the Corporation pursuant to its repurchase rights under
          the Plan, shall reduce on a share-for-share basis the number of shares
          of Common Stock available for subsequent issuance under the Plan.  In
          addition, should the exercise price of an option under the Plan
          (including any option incorporated from the Predecessor Plan) be paid
          with shares of Common Stock or should shares of Common Stock otherwise
          issuable under the Plan be withheld by the Corporation in satisfaction
          of the withholding taxes incurred in connection with the exercise of
          an option or the vesting of a stock issuance under the Plan, then the
          number of shares of Common Stock available for issuance under the Plan
          shall be reduced by the gross number of shares for which the option is
          exercised or which vest under the stock issuance, and not by the net
          number of shares of Common Stock issued to the holder of such option
          or stock issuance.

                                      -3-
<PAGE>
 
     D.   Should any change be made to the Common Stock by reason of any stock
          split, stock dividend, recapitalization, combination of shares,
          exchange of shares or other change affecting the outstanding Common
          Stock as a class without the Corporation's receipt of consideration,
          appropriate adjustments shall be made to (i) the maximum number and/or
          class of securities issuable under the Plan, (ii) the maximum number
          and/or class of securities for which the share reserve is to increase
          automatically each year, (iii) the number and/or class of securities
          for which any one person may be granted options and direct stock
          issuances over the term of the Plan, (iv) the number and/or class of
          securities for which automatic option grants are to be subsequently
          made under the Automatic Option Grant Program and (v) the number
          and/or class of securities and the exercise price per share in effect
          under each outstanding option (including any option incorporated from
          the Predecessor Plan) in order to prevent the dilution or enlargement
          of benefits thereunder.  The adjustments determined by the Plan
          Administrator shall be final, binding and conclusive.


                                  ARTICLE TWO
                      DISCRETIONARY OPTION GRANT PROGRAM
                      ----------------------------------

I.   OPTION TERMS

Each option shall be evidenced by one or more documents in the form approved by
the Plan Administrator; provided, however, that each such document shall comply
                        --------                                               
with the terms specified below.  Each document evidencing an Incentive Option
shall, in addition, be subject to the provisions of the Plan applicable to such
options.

     A.   Exercise Price.
          -------------- 

          1.    The exercise price per share shall be fixed by the Plan
                Administrator but shall not be less than eighty-five percent
                (85%) of the Fair Market Value per share of Common Stock on the
                option grant date, provided that the Plan Administrator may fix
                the exercise price at less than 85% if the optionee makes a
                payment to the Company (including payment made by means of a
                salary reduction agreement) of no less than the excess of 85% of
                the Fair Market Value of the Common Stock on the option grant
                date over such exercise price.

          2.    The exercise price shall become immediately due upon exercise of
                the option and shall, subject to the provisions of Section II of
                Article Five and the documents evidencing the option, be payable
                in one or more of the forms specified below:

                (i)    cash or check made payable to the Corporation,

                (ii)   shares of Common Stock held for the requisite period
                       necessary to avoid a charge to the Corporation's earnings
                       for financial reporting purposes and valued at Fair
                       Market Value on the exercise date, or

                (iii)  to the extent the option is exercised for vested shares,
                       through a special sale and remittance procedure pursuant
                       to which the Optionee shall concurrently provide
                       irrevocable written instructions to (a) a Corporation-
                       designated brokerage firm to effect the immediate sale of
                       the purchased shares and remit to the Corporation, out of
                       the sale proceeds available on the settlement date,
                       sufficient funds to cover the aggregate exercise price
                       payable for the purchased shares plus all applicable

                                      -4-
<PAGE>
 
                       Federal, state and local income and employment taxes
                       required to be withheld by the Corporation by reason of
                       such exercise and (b) the Corporation to deliver the
                       certificates for the purchased shares directly to such
                       brokerage firm in order to complete the sale transaction.

                Except to the extent such sale and remittance procedure is
                utilized, payment of the exercise price for the purchased shares
                must be made on the exercise date.

     B.   Exercise and Term of Options.  Each option shall be exercisable at
          ----------------------------                                      
          such time or times, during such period and for such number of shares
          as shall be determined by the Plan Administrator and set forth in the
          documents evidencing the option.  However, no option shall have a term
          in excess of ten (10) years measured from the option grant date.

     C.   Effect of Termination of Service.
          -------------------------------- 

          1.    The following provisions shall govern the exercise of any
                options held by the Optionee at the time of cessation of Service
                or death:

                (i)    Any option outstanding at the time of the Optionee's
                       cessation of Service for any reason shall remain
                       exercisable for such period of time thereafter as shall
                       be determined by the Plan Administrator and set forth in
                       the documents evidencing the option, but no such option
                       shall be exercisable after the expiration of the option
                       term.

                (ii)   Any option exercisable in whole or in part by the
                       Optionee at the time of death may be subsequently
                       exercised by the personal representative of the
                       Optionee's estate or by the person or persons to whom the
                       option is transferred pursuant to the Optionee's will or
                       in accordance with the laws of descent and distribution.

                (iii)  During the applicable post-Service exercise period, the
                       option may not be exercised in the aggregate for more
                       than the number of vested shares for which the option is
                       exercisable on the date of the Optionee's cessation of
                       Service. Upon the expiration of the applicable exercise
                       period or (if earlier) upon the expiration of the option
                       term, the option shall terminate and cease to be
                       outstanding for any vested shares for which the option
                       has not been exercised. However, the option shall,
                       immediately upon the Optionee's cessation of Service,
                       terminate and cease to be outstanding to the extent it is
                       not exercisable for vested shares on the date of such
                       cessation of Service.

                (iv)   In the event of a Corporate Transaction,the provisions of
                       Section III of this Article Two shall govern the period
                       for which the outstanding options are to remain
                       exercisable following the Optionee's cessation of Service
                       and shall supersede any provisions to the contrary in
                       this section.

          2.    The Plan Administrator shall have the discretion, exercisable
                either at the time an option is granted or at any time while the
                option remains outstanding, to:

                (i)    extend the period of time for which the option is to
                       remain exercisable following the Optionee's cessation of
                       Service from the period otherwise in effect for that

                                      -5-
<PAGE>
 
                       option to such greater period of time as the Plan
                       Administrator shall deem appropriate, but in no event
                       beyond the expiration of the option term, and/or

                (ii)   permit the option to be exercised, during the applicable
                       post-Service exercise period, not only with respect to
                       the number of vested shares of Common Stock for which
                       such option is exercisable at the time of the Optionee's
                       cessation of Service but also with respect to one or more
                       additional installments in which the Optionee would have
                       vested under the option had the Optionee continued in
                       Service.

     D.   Stockholder Rights.  The holder of an option shall have no stockholder
          ------------------                                                    
          rights with respect to the shares subject to the option until such
          person shall have exercised the option, paid the exercise price and
          become a holder of record of the purchased shares.

     E.   Repurchase Rights.  The Plan Administrator shall have the discretion
          -----------------                                                   
          to grant options which are exercisable for unvested shares of Common
          Stock. Should the Optionee cease Service while holding such unvested
          shares, the Corporation shall have the right to repurchase, at the
          exercise price paid per share, any or all of those unvested shares.
          The terms upon which such repurchase right shall be exercisable
          (including the period and procedure for exercise and the appropriate
          vesting schedule for the purchased shares) shall be established by the
          Plan Administrator and set forth in the document evidencing such
          repurchase right.

     F.   Limited Transferability of Options.  Unless the Plan Administrator
          ----------------------------------                                
          otherwise expressly approves in writing, the option shall be
          exercisable only by the Optionee during the lifetime of the Optionee,
          and shall not be assignable or transferable other than by will or by
          the laws of descent and distribution following the Optionee's death.
          However, a Non-Statutory Option may be assigned in accordance with the
          terms of a Qualified Domestic Relations Order within the meaning of
          Internal Revenue Code Section 414(p).  The assigned option may only be
          exercised by the person or persons who acquire a proprietary interest
          in the option pursuant to such Qualified Domestic Relations Order.
          The terms applicable to the assigned option (or portion thereof) shall
          be the same as those in effect for the option immediately prior to
          such assignment and shall be set forth in such documents issued to the
          assignee as the Plan Administrator may deem appropriate.


II.  INCENTIVE OPTIONS

The terms specified below shall be applicable to all Incentive Options.  Except
as modified by the provisions of this Section II, all the provisions of Articles
One, Two and Five shall be applicable to Incentive Options. Options which are
specifically designated as Non-Statutory Options when issued under the Plan
shall not be subject to the terms of this Section II.
      ---                                            

     A.   Eligibility.  Incentive Options may only be granted to Employees.
          -----------                                                      

     B.   Exercise Price.  The exercise price per share shall not be less than
          --------------                                                      
          one hundred percent (100%) of the Fair Market Value per share of
          Common Stock on the option grant date.

     C.   Dollar Limitation.  The aggregate Fair Market Value of the shares of
          -----------------                                                   
          Common Stock (determined as of the respective date or dates of grant)
          for which one or more options granted to any Employee under the Plan
          (or any other option plan of the Corporation or any Parent or
          Subsidiary) may for the first time become exercisable as Incentive
          Options during any one (1) calendar year shall not exceed the sum of
          One Hundred Thousand Dollars ($100,000).  To the extent the Employee
          holds

                                      -6-
<PAGE>
 
          two (2) or more such options which become exercisable for the first
          time in the same calendar year, the foregoing limitation on the
          exercisability of such options as Incentive Options shall be applied
          on the basis of the order in which such options are granted.

     D.   10% Stockholder.  If any Employee to whom an Incentive Option is
          ---------------                                                 
          granted is a 10% stockholder (within the meaning of Internal Revenue
          Code Section 424(d)), then the exercise price per share shall not be
          less than one hundred ten percent (110%) of the Fair Market Value per
          share of Common Stock on the option grant date, and the option term
          shall not exceed five (5) years measured from the option grant date.


III. CORPORATE TRANSACTION

     A.   In the event of any Corporate Transaction, each outstanding option
          shall automatically accelerate so that each such option shall,
          immediately prior to the effective date of the Corporate Transaction,
          become fully exercisable for all of the shares of Common Stock at the
          time subject to such option and may be exercised for any or all of
          those shares as fully-vested shares of Common Stock.  However, an
          outstanding option shall NOT so accelerate if and to the extent:  (i)
          such option is, in connection with the Corporate Transaction, either
          to be assumed by the successor corporation (or parent thereof) or to
          be replaced with a comparable option to purchase shares of the capital
          stock of the successor corporation (or parent thereof), (ii) such
          option is to be replaced with a cash incentive program of the
          successor corporation which preserves the spread existing on the
          unvested option shares at the time of the Corporate Transaction and
          provides for subsequent payout in accordance with the same vesting
          schedule applicable to such option or (iii) the acceleration of such
          option is subject to other limitations imposed by the Plan
          Administrator at the time of the option grant.  The determination of
          option comparability under clause (i) above shall be made by the Plan
          Administrator, and its determination shall be final, binding and
          conclusive.

     B.   All outstanding repurchase rights shall also terminate automatically,
          and the shares of Common Stock subject to those terminated rights
          shall immediately vest in full, in the event of any Corporate
          Transaction, except to the extent: (i) those repurchase rights are to
          be assigned to the successor corporation (or parent thereof) in
          connection with such Corporate Transaction or (ii) such accelerated
          vesting is precluded by other limitations imposed by the Plan
          Administrator at the time the repurchase right is issued.

     C.   Immediately following the consummation of the Corporate Transaction,
          all outstanding options shall terminate and cease to be outstanding,
          except to the extent assumed by the successor corporation (or parent
          thereof).

     D.   Each option which is assumed in connection with a Corporate
          Transaction shall be appropriately adjusted, immediately after such
          Corporate Transaction, to apply to the number and class of securities
          which would have been issuable to the Optionee in consummation of such
          Corporate Transaction had the option been exercised immediately prior
          to such Corporate Transaction.  Appropriate adjustments shall also be
          made to (i) the number and class of securities available for issuance
          under the Plan on both an aggregate and per Optionee basis following
          the consummation of such Corporate Transaction and (ii) the exercise
          price payable per share under each outstanding option, provided the
                                                                 --------    
          aggregate exercise price payable for such securities shall remain the
          same.

     E.   Any options which are assumed or replaced in the Corporate Transaction
          and do not otherwise accelerate at that time, shall automatically
          accelerate (and any of the Corporation's outstanding repurchase rights
          which do not otherwise terminate at the time of the Corporate
          Transaction shall

                                      -7-
<PAGE>
 
          automatically terminate and the shares of Common Stock subject to
          those terminated rights shall immediately vest in full) in the event
          the Optionee's Service should subsequently terminate by reason of an
          Involuntary Termination within eighteen (18) months following the
          effective date of such Corporate Transaction. Any options so
          accelerated shall remain exercisable for fully-vested shares until the
          earlier of (i) the expiration of the option term or (ii) the
          -------                                                     
          expiration of the one (1)-year period measured from the effective date
          of the Involuntary Termination.

     F.   The portion of any Incentive Option accelerated in connection with a
          Corporate Transaction or Change in Control shall remain exercisable as
          an Incentive Option only to the extent the applicable One Hundred
          Thousand Dollar limitation is not exceeded.  To the extent such dollar
          limitation is exceeded, the accelerated portion of such option shall
          be exercisable as a Non-Statutory Option under the Federal tax laws.

     G.   The grant of options under the Discretionary Option Grant Program
          shall in no way affect the right of the Corporation to adjust,
          reclassify, reorganize or otherwise change its capital or business
          structure or to merge, consolidate, dissolve, liquidate or sell or
          transfer all or any part of its business or assets.


IV.  CANCELLATION AND REGRANT OF OPTIONS

The Plan Administrator shall have the authority to effect, at any time and from
time to time, with the consent of the affected option holders, the cancellation
of any or all outstanding options under the Discretionary Option Grant Program
(including outstanding options incorporated from the Predecessor Plan) and to
grant in substitution new options covering the same or different number of
shares of Common Stock but with an exercise price per share based on the Fair
Market Value per share of Common Stock on the new option grant date.


                                 ARTICLE THREE
                            STOCK ISSUANCE PROGRAM
                            ----------------------

I.   STOCK ISSUANCE TERMS

Shares of Common Stock may be issued under the Stock Issuance Program through
direct and immediate issuances without any intervening option grants.  Each such
stock issuance shall be evidenced by a Stock Issuance Agreement which complies
with the terms specified below.

     A.   Purchase Price
          --------------

          1.    The purchase price per share shall be fixed by the Plan
                Administrator, but shall not be less than eighty-five percent
                (85%) of the Fair Market Value per share of Common Stock on the
                stock issuance date.

          2.    Subject to the provisions of Section II of Article Five, shares
                of Common Stock may be issued under the Stock Issuance Program
                for one or both of the following items of consideration which
                the Plan Administrator may deem appropriate in each individual
                instance:

                (i)    cash or check made payable to the Corporation, or

                                      -8-
<PAGE>
 
                (ii)   past services rendered to the Corporation (or any Parent
                       or Subsidiary).

     B.   Vesting Provisions
          ------------------

          1.   Shares of Common Stock issued under the Stock Issuance Program
               may, in the discretion of the Plan Administrator, be fully and
               immediately vested upon issuance or may vest in one or more
               installments over the Participant's period of Service or upon
               attainment of specified performance objectives.  The elements of
               the vesting schedule applicable to any unvested shares of Common
               Stock issued under the Stock Issuance Program, namely:

               (i)     the Service period to be completed by the Participant or
                       the performance objectives to be attained,

               (ii)    the number of installments in which the shares are to
                       vest,

               (iii)   the interval or intervals (if any) which are to lapse
                       between installments, and

               (iv)    the effect which death, Permanent Disability or other
                       event designated by the Plan Administrator is to have
                       upon the vesting schedule,

               shall be determined by the Plan Administrator and incorporated
               into the stock issuance agreement.

          2.   Any new, substituted or additional securities or other property
               (including money paid other than as a regular cash dividend)
               which the Participant may have the right to receive with respect
               to the Participant's unvested shares of Common Stock by reason of
               any stock dividend, stock split, recapitalization, combination of
               shares, exchange of shares or other change affecting the
               outstanding Common Stock as a class without the Corporation's
               receipt of consideration shall be issued subject to (i) the same
               vesting requirements applicable to the Participant's unvested
               shares of Common Stock and (ii) such escrow arrangements as the
               Plan Administrator shall deem appropriate.

          3.   The Participant shall have full stockholder rights with respect
               to any shares of Common Stock issued to the Participant under the
               Stock Issuance Program, whether or not the Participant's interest
               in those shares is vested.  Accordingly, the Participant shall
               have the right to vote such shares and to receive any regular
               cash dividends paid on such shares.

          4.   Should the Participant cease to remain in Service while holding
               one or more unvested shares of Common Stock issued under the
               Stock Issuance Program or should the performance objectives not
               be attained with respect to one or more such unvested shares of
               Common Stock, then those shares shall be immediately surrendered
               to the Corporation for cancellation, and the Participant shall
               have no further stockholder rights with respect to those shares.
               To the extent the surrendered shares were previously issued to
               the Participant for consideration paid in cash or cash equivalent
               (including the Participant's purchase-money indebtedness), the
               Corporation shall repay to the Participant the cash consideration
               paid for the surrendered shares and shall cancel the unpaid
               principal balance of any outstanding purchase-money note of the
               Participant attributable to such surrendered shares.

          5.   The Plan Administrator may in its discretion waive the surrender
               and cancellation of one or more unvested shares of Common Stock
               (or other assets attributable thereto) which

                                      -9-
<PAGE>
 
               would otherwise occur upon the non-completion of the vesting
               schedule applicable to such shares.  Such waiver shall result in
               the immediate vesting of the Participant's interest in the shares
               of Common Stock as to which the waiver applies.  Such waiver may
               be effected at any time, whether before or after the
               Participant's cessation of Service or the attainment or non-
               attainment of the applicable performance objectives.


II.  CORPORATE TRANSACTION

     A.   All of the outstanding repurchase rights under the Stock Issuance
          Program shall terminate automatically, and all the shares of Common
          Stock subject to those terminated rights shall immediately vest in
          full, in the event of any Corporate Transaction, except to the extent
          (i) those repurchase rights are assigned to the successor corporation
          (or parent thereof) in connection with such Corporate Transaction or
          (ii) such accelerated vesting is precluded by other limitations
          imposed in the stock issuance agreement.

     B.   Any repurchase rights that are assigned in the Corporate Transaction
          shall automatically terminate, and all the shares of Common Stock
          subject to those terminated rights shall immediately vest in full, in
          the event the Optionee's Service should subsequently terminate by
          reason of an Involuntary Termination within eighteen (18) months
          following the effective date of such Corporate Transaction.


III. SHARE ESCROW/LEGENDS

Unvested shares may, in the Plan Administrator's discretion, be held in escrow
by the Corporation until the Participant's interest in such shares vests or may
be issued directly to the Participant with restrictive legends on the
certificates evidencing those unvested shares.


                                 ARTICLE FOUR
                        AUTOMATIC OPTION GRANT PROGRAM
                        ------------------------------

I.   OPTION TERMS

     A.   Grant Dates.  Option grants shall be made on the dates specified
          -----------                                                     
          below:

          1.   Each non-employee director who is who is first elected or
               appointed as a non-employee Board member after the effective date
               of the Plan shall automatically be granted, on such initial
               election or appointment, a Non-Statutory Option to purchase 7,000
               shares of Common Stock.

          2.   On the date of each Annual Stockholders Meeting, beginning with
               the 1995 Annual Meeting, each individual who is to continue to
               serve as a non-employee director after such meeting, shall
               automatically be granted, whether or not such individual is
               standing for re-election as a Board member at that Annual
               Meeting, a Non-Statutory Option to purchase an additional 7,000
               shares of Common Stock, provided such individual has served as a
               non-employee Board member for at least six (6) months prior to
               the date of such Annual

                                      -10-
<PAGE>
 
               Meeting.  There shall be no limit on the number of such 7,000-
               share option grants any one non-employee director may receive
               over his or her period of Board service.

     B.   Exercise Price.
          -------------- 

          1.   The exercise price per share shall be equal to one hundred
               percent (100%) of the Fair Market Value per share of Common Stock
               on the option grant date.

          2.   The exercise price shall be payable in one or more of the
               alternative forms authorized under the Discretionary Option Grant
               Program.  Except to the extent the sale and remittance procedure
               specified thereunder is utilized, payment of the exercise price
               for the purchased shares must be made on the exercise date.

     C.   Option Term.  Each option shall have a term of ten (10) years measured
          -----------                                                           
          from the option grant date.

     D.   Exercise and Vesting of Options.  Each option shall be immediately
          -------------------------------                                   
          exercisable for any or all of the option shares.  However, any shares
          purchased under the option shall be subject to repurchase by the
          Corporation, at the exercise price paid per share, upon the Optionee's
          cessation of Board service prior to vesting in those shares.  Each
          grant shall vest, and the Corporation's repurchase right shall lapse,
          in a series of four (4) equal and successive quarterly installments
          over the Optionee's period of continued service as a Board member,
          with the first such installment to vest upon the Optionee's completion
          of three (3) months of Board service measured from the option grant
          date.

     E.   Effect of Termination of Board Service.  The following provisions
          --------------------------------------                           
          shall govern the exercise of any options held by the Optionee at the
          time the Optionee ceases to serve as a Board member:

          (i)   The Optionee (or, in the event of Optionee's death, the personal
                representative of the Optionee's estate or the person or persons
                to whom the option is transferred pursuant to the Optionee's
                will or in accordance with the laws of descent and distribution)
                shall have the balance of the option term in which to exercise
                each such option.

          (ii)  Following cessation of service on the Board for other than death
                or disability, the option may not be exercised in the aggregate
                for more than the number of vested shares of Common Stock for
                which the option was exercisable at the time of the Optionee's
                cessation of Board service.

          (iii) Should the Optionee cease to serve as a Board member by reason
                of death or Permanent Disability, then all shares at the time
                subject to the option shall immediately vest so that such option
                may be exercised for all or any portion of such shares as fully-
                vested shares of Common Stock.

          (iv)  Upon expiration of the option term, the option shall terminate
                and cease to be outstanding for any vested shares for which the
                option has not been exercised. However, the option shall,
                immediately upon the Optionee's cessation of Board service,
                terminate and cease to be outstanding to the extent it is not
                exercisable for vested shares on the date of such cessation of
                Board service.

                                      -11-
<PAGE>
 
II.  CORPORATE TRANSACTION/CHANGE IN CONTROL/HOSTILE TAKE-OVER

     A.   In the event of any Corporate Transaction, the shares of Common Stock
          at the time subject to each outstanding option but not otherwise
          vested shall automatically vest in full so that each such option
          shall, immediately prior to the effective date of the Corporate
          Transaction, become fully exercisable for all of the shares of Common
          Stock at the time subject to such option and may be exercised for all
          or any portion of such shares as fully-vested shares of Common Stock.
          Immediately following the consummation of the Corporate Transaction,
          each automatic option grant shall terminate and cease to be
          outstanding, except to the extent assumed by the successor corporation
          (or parent thereof).

     B.   In connection with any Change in Control, the shares of Common Stock
          at the time subject to each outstanding option but not otherwise
          vested shall automatically vest in full so that each such option
          shall, immediately prior to the effective date of the Change in
          Control, become fully exercisable for all of the shares of Common
          Stock at the time subject to such option and may be exercised for all
          or any portion of such shares as fully-vested shares of Common Stock.
          Each such option shall remain exercisable for such fully-vested option
          shares until the expiration or sooner termination of the option term
          or the surrender of the option in connection with a Hostile Take-Over.

     C.   Upon the occurrence of a Hostile Take-Over, the Optionee shall have a
          thirty (30)-day period in which to surrender to the Corporation each
          automatic option held by him or her for a period of at least six (6)
          months.  The Optionee shall in return be entitled to a cash
          distribution from the Corporation in an amount equal to the excess of
          (i) the Take-Over Price of the shares of Common Stock at the time
          subject to the surrendered option (whether or not the Optionee is
          otherwise at the time vested in those shares) over (ii) the aggregate
          exercise price payable for such shares.  Such cash distribution shall
          be paid within five (5) days following the surrender of the option to
          the Corporation.  No approval or consent of the Board shall be
          required in connection with such option surrender and cash
          distribution.

     D.   The grant of options under the Automatic Option Grant Program shall in
          no way affect the right of the Corporation to adjust, reclassify,
          reorganize or otherwise change its capital or business structure or to
          merge, consolidate, dissolve, liquidate or sell or transfer all or any
          part of its business or assets.


III. REMAINING TERMS
     ---------------

The remaining terms of each option granted under the Automatic Option Grant
Program shall be the same as the terms in effect for option grants made under
the Discretionary Option Grant Program.


                                 ARTICLE FIVE
                                 MISCELLANEOUS
                                 -------------

I.   ACCELERATION

     A.   The Plan Administrator shall have the discretion, exercisable either
          at the time an option is granted under the Discretionary Stock Option
          Program, at the time that stock is issued under the Stock Issuance
          Program or at any time while the option or stock remains outstanding,
          to provide for the

                                      -12-
<PAGE>
 
          acceleration of one or more outstanding options and the termination of
          repurchase rights on one or more outstanding shares upon the
          occurrence of such events as the Plan Administrator may determine,
          including upon a Corporate Transaction regardless or whether or not
          such options are to be assumed or replaced or the repurchase rights
          are to be assigned in the Corporate Transaction.

     B.   The Plan Administrator shall not have the discretion to provide for
          the acceleration of any options granted under the Automatic Option
          Grant Program.
 

II.  FINANCING

     A.   The Plan Administrator may permit any Optionee or Participant to pay
          the option exercise price under the Discretionary Option Grant Program
          or the purchase price for shares issued under the Stock Issuance
          Program by delivering a promissory note payable in one or more
          installments.   The terms of any such promissory note (including the
          interest rate and the terms of repayment) shall be established by the
          Plan Administrator in its sole discretion.  Promissory notes may be
          authorized with or without security or collateral.  In all events, the
          maximum credit available to the Optionee or Participant may not exceed
          the sum of (i) the aggregate option exercise price or purchase price
          payable for the purchased shares plus (ii) any Federal, state and
          local income and employment tax liability incurred by the Optionee or
          the Participant in connection with the option exercise or share
          purchase.

     B.   The Plan Administrator may, in its discretion, determine that one or
          more such promissory notes shall be subject to forgiveness by the
          Corporation in whole or in part upon such terms as the Plan
          Administrator may deem appropriate.


III. TAX WITHHOLDING

     A.   The Corporation's obligation to deliver shares of Common Stock upon
          the exercise of options or upon the issuance or vesting of such shares
          under the Plan shall be subject to the satisfaction of all applicable
          Federal, state and local income and employment tax withholding
          requirements.

     B.   The Plan Administrator may, in its discretion, provide any or all
          holders of Non-Statutory Options or unvested shares of Common Stock
          under the Plan (other than the options granted or the shares issued
          under the Automatic Option Grant Program) with the right to use shares
          of Common Stock in satisfaction of all or part of the federal, state
          and local income or employment taxes incurred by such holders in
          connection with the exercise of their options or the vesting of their
          shares.  Such right may be provided to any such holder in either or
          both of the following formats:

          (i)   Stock Withholding:  The election to have the Corporation
                -----------------                                       
                withhold, from the shares of Common Stock otherwise issuable
                upon the exercise of such Non-Statutory Option or the vesting of
                such shares, a portion of those shares with an aggregate Fair
                Market Value equal to the percentage of such taxes (not to
                exceed one hundred percent (100%)) designated by the holder.

          (ii)  Stock Delivery:  The election to deliver to the Corporation, at
                --------------                                                 
                the time the Non-Statutory Option is exercised or the shares
                vest, one or more shares of Common Stock previously acquired by
                such holder (other than in connection with the option exercise
                or share vesting triggering the taxes) with an aggregate Fair
                Market Value equal to the percentage of such taxes (not to
                exceed one hundred percent (100%)) designated by the holder.

                                      -13-
<PAGE>
 
IV.  EFFECTIVE DATE AND TERM OF THE PLAN

     A.   The Plan shall become effective on the date the Plan is adopted by the
          Board, and options may be granted under the Discretionary Option Grant
          Program from and after the effective date.  However, no options
          granted under the Plan may be exercised, and no shares shall be issued
          under the Plan, until the Plan is approved by the Corporation's
          stockholders.  If such stockholder approval is not obtained within
          twelve (12) months after such effective date, then all options
          previously granted under this Plan shall terminate and cease to be
          outstanding, and no further options shall be granted and no shares
          shall be issued under the Plan.

     B.   The Plan shall serve as the successor to the Predecessor Plan, and no
          further option grants shall be made under the Predecessor Plan after
          the effective date of the Plan.  All options outstanding under the
          Predecessor Plan as of such date shall, immediately upon approval of
          the Plan by the Corporations's stockholders, be incorporated into the
          Plan and treated as outstanding options under the Plan.  However, each
          outstanding option so incorporated shall continue to be governed
          solely by the terms of the documents evidencing such option.  No
          provision of the Plan shall be deemed to adversely affect or otherwise
          diminish the rights or obligations of the holders of such incorporated
          options with respect to their acquisition of shares of Common Stock
          which may exist under the terms of the Predecessor Plan under which
          such incorporated option was issued.  Subject to the rights of the
          optionee under the incorporated option documents and Predecessor Plan,
          the discretion delegated to the Plan Administrator hereunder may be
          exercised with respect to incorporated options to the same extent as
          it is exercisable with respect to options originally granted under
          this Plan.

     C.   The option/vesting acceleration provisions of Article Two relating to
          Corporate Transactions and Changes in Control may, in the Plan
          Administrator's discretion, be extended to one or more options
          incorporated from the Predecessor Plan which do not otherwise provide
          for such acceleration.

     D.   The Plan shall terminate upon the earliest of (i) April 27, 2005, (ii)
                                            --------                            
          the date on which all shares available for issuance under the Plan
          shall have been issued pursuant to the exercise of the options or the
          issuance of shares (whether vested or unvested) under the Plan or
          (iii) the termination of all outstanding options in connection with a
          Corporate Transaction.  Upon such Plan termination, all options and
          unvested stock issuances outstanding on such date shall thereafter
          continue to have force and effect in accordance with the provisions of
          the documents evidencing such options or issuances.


V.   AMENDMENT OF THE PLAN

     A.   The Board shall have complete and exclusive power and authority to
          amend or modify the Plan in any or all respects.  However, no such
          amendment or modification shall adversely affect the rights and
          obligations with respect to options or unvested stock issuances at the
          time outstanding under the Plan unless the Optionee or the Participant
          consents to such amendment or modification.  In addition, certain
          amendments may require stockholder approval if so determined by the
          Board or pursuant to applicable laws or regulations.

     B.   If stockholder approval is required, pursuant to the previous
          sentence, to amend the Plan to increase the number of shares of Common
          Stock available for issuance under the Plan, then upon Board approval
          of such an amendment, options to purchase shares of Common Stock may
          be granted under the Discretionary Option Grant Program and shares of
          Common Stock may be issued under

                                      -14-
<PAGE>
 
          the Stock Issuance Program that are in each instance in excess of the
          number of shares then available for issuance under the Plan, provided
          any excess shares actually issued under those programs are held in
          escrow until there is obtained stockholder approval of an amendment
          sufficiently increasing the number of shares of Common Stock available
          for issuance under the Plan.  If such stockholder approval (if so
          required) is not obtained within twelve (12) months after the date the
          first such excess issuances are made, then (i) any unexercised options
          granted on the basis of such excess shares shall terminate and cease
          to be outstanding and (ii) the Corporation shall promptly refund to
          the Optionees and the Participants the exercise or purchase price paid
          for any excess shares issued under the Plan and held in escrow,
          together with interest (at the applicable Short Term Federal Rate) for
          the period the shares were held in escrow, and such shares shall
          thereupon be automatically cancelled and cease to be outstanding.


VI.  USE OF PROCEEDS

Any cash proceeds received by the Corporation from the sale of shares of Common
Stock under the Plan shall be used for general corporate purposes.


VII. REGULATORY APPROVALS

     A.   The implementation of the Plan, the granting of any option under the
          Plan and the issuance of any shares of Common Stock (i) upon the
          exercise of any option or (ii) under the Stock Issuance Program shall
          be subject to the Corporation's procurement of all approvals and
          permits required by regulatory authorities having jurisdiction over
          the Plan, the options granted under it and the shares of Common Stock
          issued pursuant to it.

     B.   No shares of Common Stock or other assets shall be issued or delivered
          under the Plan unless and until there shall have been compliance with
          all applicable requirements of Federal and state securities laws,
          including the filing and effectiveness of the Form S-8 registration
          statement for the shares of Common Stock issuable under the Plan, and
          all applicable listing requirements of any stock exchange (or the
          Nasdaq National Market, if applicable) on which Common Stock is then
          listed for trading.


VIII.  NO EMPLOYMENT/SERVICE RIGHTS

Nothing in the Plan shall confer upon the Optionee or the Participant any right
to continue in Service for any period of specific duration or interfere with or
otherwise restrict in any way the rights of the Corporation (or any Parent or
Subsidiary employing or retaining such person) or of the Optionee or the
Participant, which rights are hereby expressly reserved by each, to terminate
such person's Service at any time for any reason, with or without cause.

                                      -15-
<PAGE>
 
                                   APPENDIX
                                   --------


The following definitions shall be in effect under the Plan:

A.   BOARD shall mean the Corporation's Board of Directors.
     -----                                                 

B.   CHANGE IN CONTROL shall mean a change in ownership or control of the
     -----------------                                                   
     Corporation effected through either of the following transactions:

     (i)  the acquisition, directly or indirectly, by any person or related
          group of persons (other than the Corporation or a person that directly
          or indirectly controls, is controlled by, or is under common control
          with, the Corporation), of beneficial ownership (within the meaning of
          Rule 13d-3 of the Securities Exchange Act of 1934) of securities
          possessing more than fifty percent (50%) of the total combined voting
          power of the Corporation's outstanding securities pursuant to a tender
          or exchange offer made directly to the Corporation's stockholders
          which the Board does not recommend such stockholders to accept, or

     (ii) a change in the composition of the Board over a period of thirty-six
          (36) consecutive months or less such that a majority of the Board
          members ceases, by reason of one or more contested elections for Board
          membership, to be comprised of individuals who either (A) have been
          Board members continuously since the beginning of such period or (B)
          have been elected or nominated for election as Board members during
          such period by at least a majority of the Board members described in
          clause (A) who were still in office at the time the Board approved
          such election or nomination.

C.   CORPORATE TRANSACTION shall mean either of the following stockholder-
     ---------------------                                               
     approved transactions to which the Corporation is a party:

     (i)    a merger or consolidation in which the Company is not the surviving
            entity, except for a transaction the principal purpose of which is
            to change the State of the Company's incorporation,

     (ii)   the sale, transfer or other disposition of all or substantially all
            of the assets of the Company in liquidation or dissolution of the
            Company, or

     (iii)  any reverse merger in which the Company is the surviving entity but
            in which securities possessing more than fifty percent (50%) of the
            total combined voting power of the Company's outstanding securities
            are transferred to holders different from those who held such
            securities immediately prior to such merger.

D.   CORPORATION shall mean Synbiotics Corporation, a California corporation.
     -----------                                                             

E.   EMPLOYEE shall mean an individual who is in the employ of the Corporation
     --------                                                                 
     (or any Parent or Subsidiary), subject to the control and direction of the
     employer entity as to both the work to be performed and the manner and
     method of performance.

F.   FAIR MARKET VALUE per share of Common Stock on any relevant date shall be
     -----------------                                                        
     determined in accordance with the following provisions:

     (i)    If the Common Stock is at the time traded on the Nasdaq National
            Market, then the Fair Market Value shall be the closing selling
            price per share of Common Stock on the date in question, as such

                                      A-1.
<PAGE>
 
            price is reported by the National Association of Securities Dealers
            on the Nasdaq National Market or any successor system. If there is
            no closing selling price for the Common Stock on the date in
            question, then the Fair Market Value shall be the closing selling
            price on the last preceding date for which such quotation exists.

     (ii)   If the Common Stock is at the time listed on any stock exchange,
            then the Fair Market Value shall be the closing selling price per
            share of Common Stock on the date in question on the Stock Exchange
            determined by the Plan Administrator to be the primary market for
            the Common Stock, as such price is officially quoted in the
            composite tape of transactions on such exchange. If there is no
            closing selling price for the Common Stock on the date in question,
            then the Fair Market Value shall be the closing selling price on the
            last preceding date for which such quotation exists.

     (iii)  If the Common Stock is at the time not traded on the Nasdaq National
            Market or listed on any stock exchange, then the Fair Market Value
            shall be determined according to whatever method is from time to
            time approved in good faith by the Board.

G.   HOSTILE TAKE-OVER shall mean a change in ownership of the Corporation
     -----------------                                                    
     effected through acquisition, directly or indirectly, by any person or
     related group of persons (other than the Corporation or a person that
     directly or indirectly controls, is controlled by, or is under common
     control with, the Corporation) of beneficial ownership (within the meaning
     of Rule 13d-3 of the Securities Exchange Act of 1934) of securities
     possessing more than fifty percent (50%) of the total combined voting power
     of the Corporation's outstanding securities  pursuant to a tender or
     exchange offer made directly to the Corporation's stockholders which the
     Board does not recommend such stockholders to accept.

H.   INCENTIVE OPTION shall mean an option which satisfies the requirements of
     ----------------                                                         
     Internal Revenue Code Section 422.

I.   INVOLUNTARY TERMINATION shall mean the termination of the Service of any
     -----------------------                                                 
     individual which occurs by reason of:

     (i)    such individual's involuntary dismissal or discharge by the
            Corporation for reasons other than Misconduct, or

     (ii)   such individual's voluntary resignation following (A) a change in
            his or her position with the Corporation which materially reduces
            his or her level of responsibility, (B) a reduction in his or her
            level of compensation (including base salary, fringe benefits and
            any non-discretionary and objective-standard incentive payment or
            bonus award) by more than fifteen percent (15%) or (C) a relocation
            of such individual's place of employment by more than fifty (50)
            miles, provided and only if such change, reduction or relocation is
            effected by the Corporation without the individual's consent.

J.   MISCONDUCT shall mean the commission of any act of fraud, embezzlement or
     ----------                                                               
     dishonesty by the Optionee or Participant, any unauthorized use or
     disclosure by such person of confidential information or trade secrets of
     the Corporation (or any Parent or Subsidiary), or any other intentional
     misconduct by such person adversely affecting the business or affairs of
     the Corporation (or any Parent or Subsidiary) in a material manner.  The
     foregoing definition shall not be deemed to be inclusive of all the acts or
     omissions which the Corporation (or any Parent or Subsidiary) may consider
     as grounds for the dismissal or discharge of any Optionee, Participant or
     other person in the Service of the Corporation (or any Parent or
     Subsidiary).

K.   NON-STATUTORY OPTION shall mean an option which is not an Incentive Option.
     --------------------                                                       

                                      A-2.
<PAGE>
 
L.   PARENT shall mean any corporation (other than the Corporation) in an
     ------                                                              
     unbroken chain of corporations ending with the Corporation, provided each
     corporation in the unbroken chain (other than the Corporation) owns, at the
     time of the determination, stock possessing fifty percent (50%) or more of
     the total combined voting power of all classes of stock in one of the other
     corporations in such chain.

M.   PERMANENT DISABILITY OR PERMANENTLY DISABLED shall mean the inability of
     --------------------------------------------                            
     the Optionee or the Participant to engage in any substantial gainful
     activity by reason of any medically determinable physical or mental
     impairment expected to result in death or to be of continuous duration of
     twelve (12) months or more.

N.   PREDECESSOR PLAN shall mean, collectively, the Corporation's existing 1986
     ----------------                                                          
     Stock Option Plan, 1987 Stock Option Plan, 1988 Stock Option Plan, 1991
     Stock Option Plan, 1994 Stock Option Plan, 1996 Stock Option Plan and 1998
     Stock Option Plan.

O.   SERVICE shall mean the provision of services to the Corporation (or any
     -------                                                                
     Parent or Subsidiary) by a person in the capacity of an Employee, a non-
     employee member of the board of directors or a consultant or independent
     advisor, except to the extent otherwise specifically provided in the
     documents evidencing the option grant.

P.   SUBSIDIARY shall mean any corporation (other than the Corporation) in an
     ----------                                                              
     unbroken chain of corporations beginning with the Corporation, provided
     each corporation (other than the last corporation) in the unbroken chain
     owns, at the time of the determination, stock possessing fifty percent
     (50%) or more of the total combined voting power of all classes of stock in
     one of the other corporations in such chain.

Q.   TAKE-OVER PRICE shall mean the greater of (i) the Fair Market Value per
     ---------------                -------                                 
     share of Common Stock on the date the option is surrendered to the
     Corporation in connection with a Hostile Take-Over or (ii) the highest
     reported price per share of Common Stock paid by the tender offeror in
     effecting such Hostile Take-Over.  However, if the surrendered option is an
     Incentive Option, the Take-Over Price shall not exceed the clause (i) price
     per share.

                                      A-3.
<PAGE>
 
COMMON STOCK PROXY           SYNBIOTICS CORPORATION          COMMON STOCK PROXY


               11011 VIA FRONTERA, SAN DIEGO, CALIFORNIA  92127


          THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS


The undersigned hereby appoints Kenneth M. Cohen and Michael K. Green, jointly
and severally, as proxyholders, each with full power to appoint his substitute,
and hereby authorizes them to vote as designated below, all the shares of Common
Stock of Synbiotics Corporation held of record by the undersigned at the close
of business on April 16, 1999, at the Annual Meeting of Shareholders to be held
on June 9, 1999, or any postponement or adjournment thereof, and to vote in
their discretion on such other business as may come before the Annual Meeting.

        THE BOARD OF DIRECTORS RECOMMENDS A VOTE FOR PROPOSALS 1 AND 2.

 1. ELECTION OF DIRECTORS.

    [_] FOR all nominees listed below (except as marked to the contrary below)

    [_] WITHHOLD AUTHORITY to vote for all nominees listed below

    (INSTRUCTION:  TO WITHHOLD AUTHORITY TO VOTE FOR ANY INDIVIDUAL NOMINEE,
    CHECK THE BOX "FOR" AND STRIKE A LINE THROUGH THE NOMINEE'S NAME IN THE LIST
    BELOW.)

    Nominees:  Patrick Owen Burns, Kenneth M. Cohen, James C. DeCesare, Brenda
               D. Gavin, M. Blake Ingle, Joseph Klein III, Donald E. Phillips

 2. APPROVAL OF THE AMENDMENT OF THE 1995 STOCK OPTION/STOCK ISSUANCE PLAN.

             [_] FOR             [_] AGAINST             [_] ABSTAIN

THIS PROXY, WHEN PROPERLY EXECUTED, WILL BE VOTED IN THE MANNER DIRECTED HEREIN
BY THE UNDERSIGNED SHAREHOLDER AND WILL BE VOTED BY THE PROXYHOLDERS AT THEIR
DISCRETION AS TO ANY OTHER MATTERS PROPERLY TRANSACTED AT THE ANNUAL MEETING.
IF THIS PROXY IS PROPERLY EXECUTED AND NO DIRECTION IS MADE, THIS PROXY WILL BE
VOTED FOR PROPOSALS 1 AND 2.

Dated: ______________ , 1999
     

- ----------------------------
(Shareholder's Signature)


- ----------------------------
(Shareholder's Signature)

Please sign exactly as your name appears on this Proxy.  If signing for trusts,
estates, partnerships, or corporations, title or capacity should be stated.  If
shares are held jointly, each holder should sign.


        PLEASE CHECK HERE IF YOU PLAN TO ATTEND THE ANNUAL MEETING.  [_]


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