IMMUNEX CORP /DE/
DEF 14A, 1995-03-24
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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<PAGE>
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                    INFORMATION REQUIRED IN PROXY STATEMENT

                               ------------------

                            SCHEDULE 14A INFORMATION
PROXY STATEMENT PURSUANT TO SECTION 14(A) OF THE SECURITIES EXCHANGE ACT OF 1934

Filed by the Registrant  /X/
Filed by a party other than the Registrant  / /

Check the appropriate box:

    / /  Preliminary Proxy Statement

    /X/  Definitive Proxy Statement

    / /  Definitive Additional Materials

    / /  Soliciting Material Pursuant to Rule 14a-11(c) or Rule 14a-12

                              IMMUNEX CORPORATION
                (Name of Registrant as Specified in Its Charter)

                              IMMUNEX CORPORATION
                   (Name of Person(s) Filing Proxy Statement)

Payment of Filing Fee (Check the appropriate box):

    /X/  $125 per Exchange Act Rule 0-11(c)(1)(ii), 14a-6(i)(1) or 14a-6(i)(2)

    /  /  $500 per  each party to the controversy  pursuant to Exchange Act Rule
       14a-6(i)(3)

    / /  Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11

                           CALCULATION OF FILING FEE

<TABLE>
<S>                      <C>                      <C>                      <C>
                                                  PER UNIT PRICE OR OTHER
                           AGGREGATE NUMBER OF      UNDERLYING VALUE OF
TITLE OF EACH CLASS OF         SECURITIES          TRANSACTION COMPUTED       PROPOSED MAXIMUM
  SECURITIES TO WHICH     TO WHICH TRANSACTION     PURSUANT TO EXCHANGE      AGGREGATE VALUE OF
  TRANSACTION APPLIES            APPLIES               ACT RULE 0-11             TRANSACTION

</TABLE>

/ /  Check box if any part of the fee is offset as provided by Exchange Act Rule
     0-11(a)(2) and identify the  filing for which the  offsetting fee was  paid
     previously.  Identify the previous filing by registration statement number,
     or the form or schedule and the date of its filing.

     Amount previously paid: _________

     Form, schedule or
   registration statement no.: _______

     Filing party: ___________________

     Date filed: _____________________

--------------------------------------------------------------------------------
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<PAGE>
                              IMMUNEX CORPORATION
                                ---------------

                    NOTICE OF ANNUAL MEETING OF SHAREHOLDERS

                      TO BE HELD WEDNESDAY, APRIL 26, 1995

                            ------------------------

To the Shareholders of Immunex Corporation:

    NOTICE  IS HEREBY GIVEN  that the Annual Meeting  of Shareholders of IMMUNEX
CORPORATION, a Washington corporation (the "Company"), will be held at the  Four
Seasons Olympic Hotel, 411 University Street, Seattle, Washington, on Wednesday,
April 26, 1995, at 9:00 a.m. (the "Annual Meeting"), for the following purposes:

    1.    To  elect  eight  directors  to  serve  until  the  Annual  Meeting of
       Shareholders next ensuing after their election and until their respective
       successors are elected and shall qualify;

    2.  To consider and  approve the increase in  the number of shares  issuable
       under the Company's Amended 1993 Stock Option Plan by 5,000,000; and

    3.  To consider and transact such other business as may properly come before
       the Annual Meeting or any adjournment or postponement thereof.

The  foregoing items of business are more fully described in the Proxy Statement
accompanying this Notice.

    The Company's Board of  Directors has fixed the  close of business on  March
14,  1995 as the record  date for the determination  of shareholders entitled to
notice of, and to vote at, the Annual Meeting.

    To ensure representation at  the Annual Meeting,  shareholders are urged  to
mark,  sign, date and return the enclosed Proxy as promptly as possible, even if
they plan to  attend the Annual  Meeting. A return  envelope, which requires  no
postage  if  mailed in  the United  States,  is enclosed  for this  purpose. Any
shareholder attending  the  Annual Meeting  may  vote  in person  even  if  such
shareholder has returned a Proxy if the Proxy is revoked in the manner set forth
in the accompanying Proxy Statement.

                                          BY ORDER OF THE BOARD OF DIRECTORS

                                          Scott G. Hallquist
                                          SECRETARY

Seattle, Washington
March 24, 1995

    PLEASE  NOTE  THAT  ATTENDANCE AT  THE  ANNUAL  MEETING WILL  BE  LIMITED TO
SHAREHOLDERS  OF  IMMUNEX   AS  OF   THE  RECORD  DATE   (OR  THEIR   AUTHORIZED
REPRESENTATIVES)  AND GUESTS  OF THE  COMPANY. TO  OBTAIN AN  ADMITTANCE TICKET,
PLEASE MARK THE APPROPRIATE BOX ON  THE ENCLOSED PROXY AND AN ADMITTANCE  TICKET
WILL BE SENT TO YOU. IF YOUR SHARES ARE HELD BY A BANK OR BROKER, YOU MAY OBTAIN
AN  ADMITTANCE TICKET BY RETURNING THE REQUEST CARD PROVIDED TO YOU BY YOUR BANK
OR BROKER.
<PAGE>
                              IMMUNEX CORPORATION
                                ---------------

                                PROXY STATEMENT
                            ------------------------

                 INFORMATION CONCERNING SOLICITATION AND VOTING

GENERAL

    The  enclosed  Proxy  is solicited  by  the  Board of  Directors  of Immunex
Corporation ("Immunex"  or the  "Company")  for use  at  the Annual  Meeting  of
Shareholders  to be  held on Wednesday,  April 26, 1995  at 9:00 a.m.  or at any
adjournment or postponement thereof (the "Annual Meeting") for the purposes  set
forth  herein and in the accompanying  Notice of Annual Meeting of Shareholders.
The Annual  Meeting  will  be  held  at the  Four  Seasons  Olympic  Hotel,  411
University  Street, Seattle, Washington. The  principal executive offices of the
Company are located at 51 University Street, Seattle, Washington 98101.

    The Company intends to first give or mail to shareholders definitive  copies
of this Proxy Statement and accompanying Proxy on or about March 24, 1995.

RECORD DATE AND OUTSTANDING SHARES

    Only  holders of record at the close of business on March 14, 1995 of shares
of common stock of the Company (the  "Common Stock") will be entitled to  notice
of,  and to  vote at, the  Annual Meeting. At  that date, there  were issued and
outstanding 39,601,699 shares of Common Stock.

REVOCABILITY OF PROXIES

    Any shareholder giving a Proxy has the power to revoke it at any time before
it is exercised. A Proxy may be revoked either by (i) filing with the  Secretary
of  the Company prior to the Annual Meeting, at the Company's executive offices,
either a written revocation  or a duly  executed Proxy bearing  a later date  or
(ii)  attending the Annual Meeting and voting in person, regardless of whether a
Proxy has previously been given. Presence at the Annual Meeting will not  revoke
the shareholder's Proxy unless such shareholder votes in person.

QUORUM

    A  quorum for the Annual Meeting shall  consist of the holders of a majority
of the  outstanding  shares of  Common  Stock entitled  to  vote at  the  Annual
Meeting, present in person or by proxy.

SOLICITATION OF PROXIES

    The  Company has  retained MacKenzie Partners,  Inc., 156  Fifth Avenue, New
York, New York, to aid in the solicitation of Proxies. It is estimated that  the
cost  of these services will be approximately $5,000, plus expenses. The cost of
soliciting Proxies will be  borne by the Company.  Proxies will be solicited  by
personal  interview, mail and telephone. In  addition, the Company may reimburse
brokerage firms and other  persons representing beneficial  owners of shares  of
Common  Stock for  their expenses in  forwarding solicitation  materials to such
beneficial owners. Proxies  may also be  solicited by certain  of the  Company's
directors,  officers  and  regular employees,  without  additional compensation,
personally or by telephone or telefax.

VOTING

    Each shareholder will be entitled to one vote for each share of Common Stock
held. Directors will be  elected by a  plurality of the  shares of Common  Stock
present by proxy or in person at the Annual Meeting. Holders of Common Stock are
not  entitled to  cumulate votes in  the election of  directors. Abstention from
voting and broker nonvotes on the election  of directors will have no impact  on
the  outcome of this proposal. The affirmative  vote of holders of a majority of
the shares of Common Stock present and entitled to vote at the Annual Meeting is
required to approve  the increase  in the number  of shares  issuable under  the
Amended  1993 Stock Option Plan. Abstention  from voting will have the practical
effect of voting  against this  proposal since such  shares are  present at  the
meeting and entitled to vote but are not voting in favor of the proposal. Broker
nonvotes  will have no effect on the outcome of this proposal since they are not
considered shares entitled to vote on the proposal.
<PAGE>
    The Company is not aware, as of the date hereof, of any matters to be  voted
upon  at the Annual Meeting  other than as stated  in the accompanying Notice of
Annual Meeting of Shareholders. The enclosed Proxy gives discretionary authority
to the persons named therein  to vote the shares in  their best judgment if  any
other matters are properly brought before the Annual Meeting.

                     PRINCIPAL HOLDERS OF VOTING SECURITIES

    The  following table sets forth as of December 31, 1994, certain information
regarding all shareholders known by the  Company to be the beneficial owners  of
more  than 5%  of the  outstanding voting  securities of  the Company,  based on
publicly available  information.  To  the Company's  knowledge,  the  beneficial
owners  listed below have sole  voting and investment power  with respect to the
shares shown as beneficially owned.

<TABLE>
<CAPTION>
                                                                                    TITLE OF    AMOUNT AND NATURE OF   PERCENT OF
                      NAME AND ADDRESS OF BENEFICIAL OWNER                           CLASS      BENEFICIAL OWNERSHIP     CLASS
--------------------------------------------------------------------------------  ------------  --------------------   ----------
<S>                                                                               <C>           <C>                    <C>
American Cyanamid Company (1)                                                     Common Stock       21,153,580          53.6%
One Cyanamid Plaza
Wayne, New Jersey 07470
Wellington Management Company                                                     Common Stock       2,069,270            5.3%
75 State Street
Boston, Massachusetts 02109
<FN>
------------------------
(1)  American Cyanamid  Company ("Cyanamid")  is a  wholly owned  subsidiary  of
     American Home Products Corporation ("American Home Products").
</TABLE>

SECURITY OWNERSHIP OF MANAGEMENT

    The  following  table  sets  forth  as of  March  14,  1995,  the  number of
outstanding voting  securities of  the Company  beneficially owned  by (i)  each
director  and  each  nominee, (ii)  each  of  the current  and  former executive
officers for whom compensation  is reported in this  Proxy Statement, and  (iii)
all current directors and executive officers as a group:

<TABLE>
<CAPTION>
                                                                                    TITLE OF    AMOUNT AND NATURE OF   PERCENT OF
                            NAME OF BENEFICIAL OWNER                                 CLASS      BENEFICIAL OWNERSHIP     CLASS
--------------------------------------------------------------------------------  ------------  --------------------   ----------
<S>                                                                               <C>           <C>                    <C>
Steven Gillis                                                                     Common Stock       460,262(1)           1.2%
David L. Urdal                                                                    Common Stock        74,454(2)            *
Scott G. Hallquist                                                                Common Stock        49,452(2)            *
Michael L. Kranda                                                                 Common Stock        32,671(2)            *
Edward V. Fritzky                                                                 Common Stock        11,200(3)            *
Douglas G. Southern                                                               Common Stock        10,534(4)            *
Kirby L. Cramer                                                                   Common Stock         3,000(5)            *
Edith W. Martin                                                                   Common Stock         3,000(5)            *
John E. Lyons                                                                     Common Stock         2,000(5)            *
Charles J. Homcy                                                                  Common Stock           200               *
Joseph J. Carr                                                                    Common Stock           --                --
Robert A. Essner                                                                  Common Stock           --                --
All current directors and executive officers as a group (15 persons)              Common Stock       655,868(6)           1.7%
<FN>
------------------------
 *   Less than 1% of the outstanding shares of Common Stock.
</TABLE>

                                       2
<PAGE>
<TABLE>
<S>  <C>
(1)  Excludes  39,000 shares of Common Stock held by three trusts established by
     Dr. Gillis for the benefit of his family. Dr. Gillis is not the trustee  of
     such trusts and disclaims beneficial ownership of such shares.

(2)  Includes 8,000 shares that are issuable upon exercise of stock options that
     are currently exercisable or are exercisable within 60 days.

(3)  Includes  10,000 shares  that are issuable  upon exercise  of stock options
     that are currently exercisable or are exercisable within 60 days.

(4)  Includes 6,000 shares that are issuable upon exercise of stock options that
     are currently exercisable or are exercisable within 60 days.

(5)  Includes 2,000 shares that are issuable upon exercise of stock options that
     are currently exercisable or are exercisable within 60 days.

(6)  Includes 51,000 shares  that are  issuable upon exercise  of stock  options
     that are currently exercisable or are exercisable within 60 days.
</TABLE>

                             ELECTION OF DIRECTORS

    A  Board of Directors consisting  of eight directors will  be elected at the
Annual Meeting to hold office for a  term of one year or until their  successors
are elected and shall qualify.

    Pursuant  to  the  Amended and  Restated  Governance Agreement  dated  as of
December  15,  1992  (the  "Governance  Agreement"),  Cyanamid  is  entitled  to
designate   three  Investor   Directors  and   one  Independent   Director.  See
"Relationship  with  American  Cyanamid  Company  and  American  Home   Products
Corporation  -- Governance Agreement  -- Designation of  Candidates for Board of
Directors." Dr. Charles J. Homcy, who was  elected by the Board of Directors  to
serve  as an  Investor Director,  has not  been renominated  and is  expected to
resign. Cyanamid has not yet designated a replacement Investor Director to  fill
the  vacancy created by the expected resignation  of Dr. Homcy, nor designated a
fourth Independent Director as permitted under the Governance Agreement. Pending
Cyanamid's decision regarding such designations,  one vacancy among each of  the
Investor  Directors and Independent Directors  will exist. Therefore, only eight
nominees have been nominated and approved by the Board of Directors for election
at the  Annual Meeting.  However,  Cyanamid is  expected to  designate  director
nominees  for election by the Board of Directors to fill such vacancies, and may
do so at any time. Proxies may not be voted for a greater number of persons than
the number of nominees named.

    The Board of Directors  has unanimously approved  the nominees named  below,
who  were  designated  in  accordance  with  the  Governance  Agreement.  Unless
otherwise  instructed,  it  is  the  intention  of  the  persons  named  in  the
accompanying  Proxy to vote shares represented  by properly executed Proxies for
such nominees. Although the Board of Directors anticipates that all the nominees
will be available to serve as directors  of the Company, should any one or  more
of them not accept the nomination, or otherwise be unwilling or unable to serve,
it  is  intended  that  the Proxies  will  be  voted for  the  election  of such
substitute nominees  as may  be  designated in  accordance with  the  Governance
Agreement.

                                       3
<PAGE>
    The following table sets forth the name and age of each nominee for election
as  a director, the positions  and offices held by  the nominee with the Company
and the period during which the nominee has served as a director of the Company:

<TABLE>
<CAPTION>
                                   POSITIONS AND OFFICES             DIRECTOR
      NAME         AGE               WITH THE COMPANY                  SINCE
-----------------  ----  -----------------------------------------  -----------
<S>                <C>   <C>                                        <C>
Edward V. Fritzky   44   Chief Executive Officer; Chairman of the         1994
                          Board
Michael L. Kranda   41   President; Chief Operating Officer;              1991
                          Director
Steven Gillis       41   Director                                         1981
Joseph J. Carr      52   Director                                         1995
Kirby L. Cramer     58   Director                                         1987
Robert A. Essner    47   Director                                         1995
John E. Lyons       69   Director                                         1993
Edith W. Martin     49   Director                                         1993
</TABLE>

    Mr. Fritzky was named the Company's Chief Executive Officer and Chairman  of
the  Board  in  January  1994.  Mr.  Fritzky  served  as  President  of  Lederle
Laboratories, a division of Cyanamid, from 1992 to 1994 and as Vice President of
Lederle Laboratories from 1989 to  1992. Prior to joining Lederle  Laboratories,
Mr.  Fritzky was an  executive of Searle Pharmaceuticals,  Inc., a subsidiary of
Monsanto Company. During his tenure at  Searle, Mr. Fritzky was Vice  President,
Marketing,  and later President  and General Manager of  Searle Canada, Inc. and
Lorex Pharmaceuticals, a joint venture company.

    Mr. Kranda  has been  a director  of the  Company since  1991. He  has  been
employed  by  the  Company since  July  1985, initially  as  Director, Corporate
Development. From January  1986 to July  1988, he served  as General Manager  of
Immunology  Ventures, the Company's  partnership with Eastman  Kodak Company. In
July 1988, Mr. Kranda was elected  Executive Vice President and Chief  Operating
Officer of the Company. In October 1990, he was elected President, retaining the
office  of Chief Operating Officer. Mr. Kranda previously served as President of
Immunex Manufacturing  Corporation,  the Company's  wholly  owned  manufacturing
subsidiary.  He received his M.B.A. in Finance from the University of Washington
in 1984.  Mr.  Kranda  currently serves  as  a  director of  the  Woodland  Park
Zoological   Society  and  the  Washington  Research  Foundation,  both  private
nonprofit entities.

    Dr. Gillis is a co-founder of the Company and served as a director since the
Company's formation  in 1981.  From 1981  to 1994,  Dr. Gillis  was employed  as
Executive  Vice President and Chief Scientific  Officer of the Company, and from
September 1993 to  January 1994, served  as Acting Chief  Executive Officer  and
Chairman.  Dr. Gillis  also served as  President and Chief  Executive Officer of
Immunex Research  and Development  Corporation ("IRDCO"),  the Company's  wholly
owned  research and development subsidiary. IRDCO was dissolved in January 1995,
and all of its  operations, assets and employees  were merged with the  Company.
Dr.  Gillis is currently employed  as Chairman and CEO  of Corixa Corporation, a
privately held biotechnology company.

    Mr. Carr was  named a director  of the  Company in January  1995. He  joined
American  Home Products,  a pharmaceutical  and healthcare  products company, in
1982, and  served in  various executive  capacities prior  to being  named  Vice
President  in 1989. In April 1993, Mr.  Carr was appointed Group Vice President,
and in May 1993 was appointed Senior Vice President.

    Mr. Cramer has  been a director  of the  Company since 1987.  Mr. Cramer  is
Chairman Emeritus of Hazleton Laboratories Corporation. He is a Trustee Emeritus
and  Past  President of  the University  of  Virginia's Colgate  Darden Graduate
School of Business Administration. He also  serves on the board of directors  of
Advanced   Technology  Laboratories,   Inc.,  Commerce   Bancorporation,  Landec
Corporation and Unilab, Inc. Mr. Cramer is also a director of The Commerce  Bank
of  Washington,  Olympic Boat  Company,  Unilab Group  Ltd.,  Northwestern Trust
Company and other privately held companies.

                                       4
<PAGE>
    Mr. Essner was named a  director of the Company  in January 1995. He  joined
American Home Products in 1989 as Senior Vice President, Sales and Marketing, of
its  Wyeth-Ayerst  Laboratories  division  ("Wyeth-Ayerst").  In  1991,  he  was
appointed  Executive  Vice   President,  and  in   March  1993,  President,   of
Wyeth-Ayerst.  Prior to joining American Home  Products, Mr. Essner was employed
by Sandoz  Pharmaceuticals Corporation  for  13 years,  most recently  as  Chief
Operating Officer.

    Mr.  Lyons has been a director of  the Company since 1993. Mr. Lyons retired
as Vice Chairman of the  Board of Merck & Company  ("Merck") in 1991. He  joined
Merck  in 1950 as a  Research Chemist and held a  number of senior marketing and
sales positions in the Merck,  Sharp & Dohme division  of Merck, serving as  its
President from 1975 to 1985. He was appointed Corporate Senior Vice President in
1982,  Executive Vice President of Merck in 1985, and Vice Chairman of the Board
in 1988.  Mr. Lyons  currently serves  on  the board  of directors  of  Synaptic
Pharmaceutical  Company, Matrix Pharmaceutical  Company, Philadelphia College of
Pharmacy and Fordham University.

    Dr. Martin has been a director of the Company since 1993. Dr. Martin is  the
Executive  Vice  President  and Chief  Technology  Officer of  the  Student Loan
Marketing Association ("Sallie Mae"),  a position she  has held since  September
1994. In this position, she is responsible for all information technology within
Sallie  Mae  and  all  technology-driven  new  businesses,  joint  ventures  and
acquisitions. Prior  to joining  Sallie Mae,  Dr. Martin  was employed  as  Vice
President  and Chief Information Officer of the International Telecommunications
Satellite Organization ("INTELSAT") since  1992. She had overall  responsibility
for  all  information  and  computing  systems,  which  included  Ground Network
Engineering and Projects,  Information Systems  Management, Conference  Services
and  Language Services. Prior to joining INTELSAT, Dr. Martin was Vice President
of The  Boeing Company,  and founded  and directed  the Boeing  High  Technology
Center. Dr. Martin currently serves on the board of directors of Medtronic, Inc.
and Information Resources, Inc.

INFORMATION ON COMMITTEES OF THE BOARD OF DIRECTORS AND MEETINGS

    During the last fiscal year there were seven meetings of the Company's Board
of  Directors.  All  incumbent directors  attended  at  least 75%  of  the Board
meetings held and at least 75% of the Committee meetings held of which they were
a member, except that  Dr. Homcy attended  two of the  four Board meetings  held
during 1994 following his appointment to the Board.

    In  accordance  with  the  Governance  Agreement,  the  Board  of  Directors
maintains an Audit Committee, a  Compensation Committee, a Nominating  Committee
and a Stock Option Plan Administration Committee.

    The  Audit Committee, currently composed of Messrs. Cramer and Lyons and Dr.
Martin, is responsible, among  other things, for  recommending the selection  of
certified  public accountants to the Board of Directors, reviewing the scope and
results of the audits,  approving nonaudit services  performed by the  certified
public   accountants  and  reviewing  the   Company's  accounting  policies  and
procedures and system  of internal controls.  During the past  year, there  were
four Audit Committee meetings.

    The  Compensation Committee, currently composed  of Messrs. Cramer and Lyons
and Dr. Martin,  is responsible,  among other  things, for  recommending to  the
Board  of Directors the adoption and amendment of all employee benefit plans and
arrangements and  the engagement  of,  terms of  any employment  agreements  and
arrangements  with, and terminations of, all  corporate officers of the Company.
During the past year, there were two Compensation Committee meetings.

    The Nominating Committee, currently composed of Messrs. Carr and Kranda,  is
responsible  for the nomination of directors and the solicitation of shareholder
proxies. During the past year, there was one Nominating Committee meeting.

    The Stock  Option  Plan  Administration  Committee,  currently  composed  of
Messrs.   Carr,  Cramer,  Essner  and  Lyons  and  Drs.  Martin  and  Homcy,  is
responsible, among other things, for recommending

                                       5
<PAGE>
to the Board of Directors the adoption  and amendment of all stock option  plans
of  the Company and for the administration  of such plans. During the past year,
there were four Stock Option Plan Administration Committee meetings.

COMPENSATION OF DIRECTORS

    Independent Directors  (as defined  below) receive  $6,000 per  quarter.  In
addition,  they  receive  $1,000 per  quarter  for  serving as  the  Chair  of a
Committee, and $1,000  for each Board  of Directors and  each Committee  meeting
attended  in  person and  $500 for  each  such meeting  attended telephonically.
Management Directors  and  Investor  Directors (as  defined  below)  receive  no
additional compensation for attending Board or Committee meetings.

    Under  the  Company's  Stock  Option Plan  for  Nonemployee  Directors, each
Independent Director receives a one-time grant  of an option to purchase  10,000
shares  of  Common  Stock on  the  day  such director  is  initially  elected or
appointed to the  Board. Such  options vest at  a rate  of 20% per  year over  a
five-year period.

    Mr. Cramer also received $14,400 during the year ended December 31, 1994 for
consulting  services  provided to  the Company  relating  to the  acquisition of
Cyanamid by American Home Products and the Company's stock option plans.

                    APPROVAL OF INCREASE IN NUMBER OF SHARES
                 ISSUABLE UNDER AMENDED 1993 STOCK OPTION PLAN

    The Company's Amended 1993  Stock Option Plan (the  "1993 Plan") provides  a
means  whereby  selected employees,  officers and  directors  of Immunex  may be
granted incentive stock options ("ISOs") or nonqualified stock options  ("NSOs")
to  purchase shares of Common Stock.  Approximately 700 persons are eligible for
participation in the 1993 Plan. Presently, subject to adjustment required in the
event of any  recapitalization of the  Company, the aggregate  amount of  Common
Stock  that may be  issued upon exercise  of all options  granted under the 1993
Plan may not exceed 1,225,267 shares.  On February 2, 1995, the Company's  Board
of  Directors unanimously adopted an amendment to the 1993 Plan that, subject to
shareholder approval,  would  authorize an  additional  5,000,000 shares  to  be
available  for the granting  of options under the  1993 Plan. As  of the date of
this Proxy Statement, 5,932 shares remained available for future grant under the
1993 Plan.

    The Board believes that  the additional options  would, among other  things,
promote  the  interests of  the Company  and its  shareholders by  assisting the
Company in attracting, retaining and stimulating the performance of officers and
key employees. The  Board believes  that the existing  options have  contributed
substantially to the successful achievement of these objectives.

    ADMINISTRATION.    The 1993  Plan  is administered  by  a Stock  Option Plan
Administration Committee (the  "Committee") appointed by  the Board. Except  for
the  terms and conditions explicitly  set forth in the  1993 Plan, the Committee
has the authority to determine all matters relating to options granted under the
1993 Plan, including the selection of the individuals to be granted options, the
number of shares to be subject to each option, the exercise price (which may not
be less than fair market value per share, in the case of ISOs, and not less than
par value per share, in the case of  NSOs), and all the terms and conditions  of
the options.

    ADJUSTMENTS  UPON CHANGES  IN CAPITALIZATION.   If there is  any increase or
decrease in  the  number of  issued  shares of  Common  Stock resulting  from  a
split-up  or  consolidation of  shares or  any like  capital adjustment,  or the
payment of any stock dividend, the aggregate number and class of shares on which
options may be  granted under  the 1993  Plan, the  number and  class of  shares
covered by each outstanding option and the exercise price per share thereof (but
not the total price) will be proportionately adjusted.

    EFFECT  OF LIQUIDATION OR RECAPITALIZATION.  If the Company is involved in a
merger (other than  a merger in  which the holders  of Common Stock  immediately
prior to the merger have the same

                                       6
<PAGE>
proportionate ownership of common stock in the surviving corporation immediately
after  the merger), consolidation, reorganization,  liquidation or other similar
transaction, as a result of which the Company's shareholders receive cash, stock
or other property  in exchange  for their shares  of Common  Stock, all  options
granted  under the  1993 Plan  will terminate, but  the holders  of options (the
"Optionees")  will   have  the   right  immediately   prior  to   such   merger,
consolidation,  reorganization,  liquidation  or  other  similar  transaction to
exercise such Optionee's option in whole or  in part whether or not the  vesting
requirements  with respect  thereto have  been met.  In the  event, however, the
Company's shareholders receive capital stock of another corporation in  exchange
for  their  shares of  Common  Stock in  a merger,  the  Company and  such other
corporation may determine that  all outstanding options  will be converted  into
options to purchase shares of such other corporation's capital stock.

    DESCRIPTION  OF  TERMS  AND  CONDITIONS  OF OPTIONS.    The  following  is a
description of the specific terms that  all options granted under the 1993  Plan
must  include. Additional terms that the  Committee deems advisable and that are
not inconsistent with the 1993 Plan may be included in the written agreement  to
be issued to evidence options granted.

    PAYMENT  OF EXERCISE PRICE.  The price of shares purchased upon the exercise
of options will  be paid in  cash or by  check. To the  extent permitted by  the
Committee,  however, an option may be exercised by (i) delivery of shares of the
Company's capital stock held by the Optionee having a fair market value equal to
the exercise price, provided that such stock  has been held by the Optionee  for
at  least six months, (ii) delivery of a properly executed notice, together with
irrevocable instructions to  a broker to  deliver to the  Company the amount  of
sale  or  loan  proceeds to  pay  the exercise  price,  or (iii)  delivery  of a
full-recourse promissory note executed by the Optionee and secured by the shares
issued upon exercise.

    TERM AND MATURITY.  Subject to certain restrictions concerning greater  than
10%  shareholders, each option expires  10 years from the  date of grant. Unless
modified by the Committee, options vest  in five equal installments at the  rate
of 20% per year following the date of grant.

    EXERCISE  OF OPTIONS.  Subject to the option's vesting schedule, each option
may be exercised in whole or in part;  however, no fewer than 20% of the  shares
purchasable  under the option (or the remaining shares then purchasable, if less
than 20%) may be purchased upon any exercise of option rights.

    HOLDING PERIODS.    Persons  subject  to Section  16(b)  of  the  Securities
Exchange  Act of  1934, as  amended (the "Exchange  Act"), must  hold the shares
issued upon exercise of an  option for six months from  the date the option  was
granted. The Committee may require an Optionee to give the Company prompt notice
of  any disposition of shares of Common Stock acquired by the exercise of an ISO
prior to the expiration of two years after  the date of grant of the option  and
one year after the date of exercise.

    TERMINATION  OF RELATIONSHIP  WITH THE COMPANY.   Options  granted under the
1993 Plan terminate and may not be exercised if the Optionee's relationship with
the Company is terminated, except that:

        (i) If the Optionee dies while such Optionee has a relationship with the
    Company or an affiliate,  or within three months  after termination of  such
    relationship  (or 12 months in the  case of totally disabled Optionees), the
    option may be exercised at any time within one year following the Optionee's
    death by the person or persons to whom the rights of the Optionee under  the
    option  pass by will or by the laws of descent and distribution, but only to
    the extent the option was exercisable on the date of termination;

        (ii) If the Optionee's  relationship with the  Company is terminated  by
    reason  of the Optionee's having become  totally disabled (as defined in the
    1993 Plan),  the Optionee  may exercise  the option  at any  time within  12
    months   following  such  termination,  but  only   to  the  extent  it  was

                                       7
<PAGE>
    exercisable on the date of such  termination, unless by its terms it  sooner
    terminates  and expires, in which case  the Optionee shall have such shorter
    period of time in which to exercise the option; and

       (iii) If the Optionee's relationship  with the Company is terminated  for
    any  other reason  other than  by the  Company for  cause, the  Optionee may
    exercise the option at any time  within 90 days after such termination,  but
    only  to the  extent it  was exercisable  on the  date of  such termination,
    unless by its  terms it  sooner terminates and  expires, in  which case  the
    Optionee  shall have such  shorter period of  time in which  to exercise the
    option.

    AMENDMENT AND TERMINATION.  Unless sooner terminated by the Board, the  1993
Plan will terminate on March 11, 2003. The Board may amend or terminate the 1993
Plan at any time, provided that the approval of the holders of a majority of the
Company's  outstanding shares of voting capital stock voting either in person or
by proxy at a duly held shareholders meeting is necessary in order to adopt  any
amendment  that will (i) increase the number  of shares that may be issued under
the 1993 Plan,  (ii) with  respect to  NSOs, materially  modify the  eligibility
requirements,  or, with respect to ISOs,  change the designation of the eligible
participants or class  of participants, (iii)  materially increase the  benefits
accruing  to the participants  under the 1993 Plan,  or (iv) require shareholder
approval under applicable law, including, but  not limited to, Section 16(b)  of
the Exchange Act. Amendment or termination of the 1993 Plan may not, without the
Optionee's  consent,  alter  or  impair  any  rights  or  obligations  under any
then-outstanding option.

    FEDERAL INCOME TAX CONSEQUENCES.  There are generally no federal income  tax
consequences  to  the Optionee  or  to the  Company by  reason  of the  grant or
exercise of  a  valid ISO.  Upon  exercise of  an  ISO, the  Optionee  does  not
recognize  taxable income; however, the amount  by which the Common Stock's fair
market value at  the time  of exercise exceeds  the option  exercise price  will
constitute income for purposes of calculating the Optionee's alternative minimum
tax  liability, if  any. There  are no  federal income  tax consequences  to the
Company when the Optionee exercises a valid ISO.

    Upon the disposition  of Common Stock  acquired through the  exercise of  an
ISO,  any resulting gain or loss will  constitute long-term capital gain or loss
if the disposition occurs at least two  years after the grant date and one  year
after the exercise date of the corresponding option or if the disposition occurs
after  the Optionee's death.  If these two  holding periods are  not met and the
disposition occurs prior to the Optionee's death, the disposition will cause the
Optionee to recognize  ordinary income in  the amount by  which the fair  market
value  of the Common  Stock at the  time of exercise  exceeded the option price;
gain attributable to  further appreciation of  the fair market  value after  the
exercise  of  the  option  will constitute  long-  or  short-term  capital gain,
depending on whether the Common Stock has  been held for more than one year.  If
the fair market value of the Common Stock declines during the period between the
exercise  and disposition, then the amount  of ordinary income that the Optionee
must recognize is limited to  the amount by which the  fair market value at  the
time  of  disposition  exceeds  the option  price.  If  the  Optionee recognizes
ordinary income  in  connection  with an  ISO,  the  Company is  entitled  to  a
corresponding  business expense  deduction in  an amount  equal to  the ordinary
income recognized  by the  Optionee.  Currently, any  ordinary income  that  the
Optionee recognizes in connection with the ISO is not subject to withholding for
income  or employment  taxes, but the  Internal Revenue  Service is reevaluating
this position.

    NSOs under the 1993 Plan are  taxed pursuant to the rules governing  options
that  are not ISOs. There are no federal income tax consequences to the Optionee
or the Company by  reason of the  grant of a  NSO. Upon exercise  of a NSO,  the
Optionee  will recognize  ordinary income in  an amount equal  to the difference
between the fair market value  of the Common Stock on  the date of exercise  and
the  option  exercise price.  Upon  such exercise,  the  Company is  required to
withhold from regular wages or supplemental wage payments an amount based on the
ordinary income recognized on the exercise of such NSO by the Optionee, or  must
otherwise ensure that the amount of tax required to be withheld is available for
payment  in money. The 1993 Plan permits  an Optionee to satisfy such Optionee's
withholding liability  by having  the  Company withhold  that number  of  shares
otherwise issuable

                                       8
<PAGE>
having  a fair market  value equal to the  Optionee's withholding tax liability.
Subject to the test of reasonableness and satisfaction of applicable withholding
requirements, the Company will  be entitled to a  business expense deduction  in
the  tax year in  which the exercise occurs  in an amount  equal to the ordinary
income recognized by the Optionee. There are no tax consequences to the  Company
by  reason of  the disposition  by the  Optionee of  Common Stock  acquired upon
exercise of a NSO.

    The aggregate fair market  value of Common Stock  available pursuant to  all
ISOs  exercisable by an Optionee  for the first time  during a calendar year may
not exceed $100,000. This limitation is applied by using the stock's fair market
value as of the grant date of the underlying option, and by considering all ISOs
under all plans  of the  Company or  any parent  or subsidiary  company. To  the
extent  the Optionee's ISOs exceed  the $100,000 limit, they  will be treated as
NSOs.

    The affirmative vote of holders of a majority of the shares of Common  Stock
present  and entitled to vote  at the Annual Meeting  is required to approve the
increase in the number of shares issuable under the 1993 Plan.

    THE BOARD OF DIRECTORS RECOMMENDS THAT SHAREHOLDERS VOTE FOR APPROVAL OF THE
INCREASE IN THE NUMBER OF SHARES ISSUABLE UNDER THE 1993 PLAN.

                                       9
<PAGE>
            RELATIONSHIP WITH AMERICAN CYANAMID COMPANY AND AMERICAN
                           HOME PRODUCTS CORPORATION

    On June  1,  1993, the  Company's  predecessor ("Predecessor  Immunex")  was
merged   (the  "Merger")   into  Lederle  Oncology   Corporation,  a  previously
nondistinct operating  unit of  Cyanamid, pursuant  to an  Amended and  Restated
Agreement  and Plan of Merger  dated as of December  15, 1992, among Predecessor
Immunex, Cyanamid and  certain other parties  thereto (the "Merger  Agreement").
Each  share of Common Stock of Predecessor Immunex outstanding immediately prior
to the  effective  time of  the  Merger  (the "Effective  Time")  was  converted
pursuant  to the Merger into the  right to receive $21 in  cash and one share of
Common Stock of the newly formed entity, the Company. Cyanamid contributed  $350
million  in cash and certain assets  and contractual obligations of its oncology
business in the United  States and Canada (the  "Lederle Oncology Business")  to
Lederle Oncology Corporation just prior to the Effective Time. Cyanamid received
53.5%  of  the  Company's  Common Stock  outstanding  immediately  following the
Effective Time, on a fully diluted basis.

    Simultaneously with entering into the Merger Agreement, Predecessor  Immunex
and  Cyanamid entered  into the  Governance Agreement,  which sets  forth, among
other things, certain agreements  of the parties relating  to (i) the  corporate
governance  of the Company, including the composition of its Board of Directors,
(ii) rights of Cyanamid  to purchase additional shares  of the Company's  Common
Stock  from  the Company  upon the  occurrence of  certain events,  (iii) future
acquisitions and  dispositions of  the Company's  securities by  Cyanamid,  (iv)
rights  of members of the Company's Board of Directors designated by Cyanamid to
approve certain corporate actions, (v)  the requirement that a supermajority  of
the  members  of  the Company's  Board  of Directors  approve  certain corporate
actions, and (vi) payments to  be made by Cyanamid to  the Company in the  event
that  the  products  of the  Lederle  Oncology  Business and  certain  other new
products of  Immunex do  not  achieve specified  revenue targets.  In  addition,
pursuant  to  the  Merger  Agreement, Immunex,  Cyanamid  and  certain  of their
respective subsidiaries entered into  certain agreements at  the closing of  the
Merger   relating  to  cooperation  in  research  and  development,  supply  and
manufacture of certain products, and other matters.

    In November 1994,  all the outstanding  shares of common  stock of  Cyanamid
were  acquired by American  Home Products. Cyanamid is  currently a wholly owned
subsidiary of American Home Products.  Pursuant to an Agreement dated  September
20,  1994 between the Company and American Home Products, American Home Products
agreed to maintain the  separate existence and  business operations of  Cyanamid
and  its  subsidiaries that  have obligations  to  the Company,  with sufficient
financial  assets,  facilities,  employees,   management  and  other   resources
necessary  to permit Cyanamid and such subsidiaries to continue to perform their
obligations to  the  Company  under  the  Governance  Agreement  and  the  other
agreements  that were entered into in  connection with the Merger. American Home
Products also agreed to be bound by the standstill provisions of the  Governance
Agreement  (see "Governance Agreement  -- Standstill Provisions")  to the extent
such provisions apply to Cyanamid.

GOVERNANCE AGREEMENT

    DESIGNATION OF CANDIDATES FOR BOARD OF DIRECTORS

    Pursuant to  the  Governance Agreement,  the  Company's Board  of  Directors
consists  of nine directors. Three directors  are designated by the Company (the
"Management  Directors"),  three  are  designated  by  Cyanamid  (the  "Investor
Directors"),  and three independent directors are designated by agreement of the
Company and Cyanamid (the  "Independent Directors"). Cyanamid  has the right  to
designate  an additional Independent  Director to the  Company's Board. Cyanamid
has not yet exercised such right.

    At all times  during the  term of the  Governance Agreement,  the number  of
directors  that  Cyanamid  and  the  management of  Immunex  have  the  right to
designate will be determined by the percentage interest of Immunex  beneficially
owned  by Cyanamid. If Cyanamid's interest is: (i) below 20%, Cyanamid will have
no right to designate any directors, and the management of Immunex will have the
right to designate  six Management Directors;  (ii) 20% or  above but less  than
35%, Cyanamid will

                                       10
<PAGE>
have the right to designate one Investor Director, and the management of Immunex
will  have the right to designate five  Management Directors; (iii) 35% or above
but less  than 45%,  Cyanamid will  have  the right  to designate  two  Investor
Directors,  and the management of Immunex will  have the right to designate four
Management Directors; (iv) 45%  or above but less  than 65%, Cyanamid will  have
the  right to designate three Investor  Directors, and the management of Immunex
will have the  right to  designate three Management  Directors; and  (v) 65%  or
above,  Cyanamid will  have the right  to designate four  Investor Directors, by
adding an  additional Investor  Director  to the  Board  of Directors,  and  the
management  of  Immunex  will  have  the  right  to  designate  three Management
Directors.

    In the event that Cyanamid's interest  is such that there are more  Investor
Directors or Management Directors on the Board of Directors than Cyanamid or the
management  of Immunex, as the case may be, has the right to designate, Cyanamid
or the management of Immunex, as the case may be, will promptly cause to resign,
and take all other action reasonably  necessary to cause the prompt removal  of,
that  number of Investor Directors or Management  Directors, as the case may be,
as required to  make the remaining  number of Investor  Directors or  Management
Directors conform with the formula described in the preceding paragraph.

    With certain exceptions, Cyanamid and the Management Directors will have the
right  to  designate  replacements  for  directors  designated  pursuant  to the
Governance Agreement by Cyanamid or  the Management Directors, respectively,  at
the  termination of such director's term or upon death, resignation, retirement,
disqualification, removal from  office or  other cause. The  Board of  Directors
will  elect  each  person  so  designated  upon  nomination  by  the  Nominating
Committee, which consists of an equal number of directors designated by each  of
Immunex  and Cyanamid.  No individual  who is  an officer,  director, partner or
principal shareholder of any  competitor of Immunex or  any of its  subsidiaries
(other  than  Cyanamid and  its  affiliates) may  be  designated to  serve  as a
director of Immunex.

    In any election of directors or  any meeting of the shareholders of  Immunex
called  expressly for the removal of directors, Cyanamid and its affiliates will
vote their shares of Common  Stock for all nominees  in proportion to the  votes
cast  by  the  other  shareholders  of Immunex,  except  that  Cyanamid  and its
affiliates may cast any or all of their votes, in their sole discretion, (i)  in
favor of any nominee designated by Cyanamid pursuant to the Governance Agreement
and  (ii) in connection with any election contest to which Rule 14a-11 under the
Exchange Act  applies. With  certain limited  exceptions, in  all other  matters
submitted  to a vote of shareholders of Immunex, Cyanamid may vote any or all of
its shares in its sole discretion.

    CERTAIN APPROVAL RIGHTS

    So long  as  Cyanamid has  the  right to  designate  at least  two  Investor
Directors  to  the Board  of  Directors, the  approval of  at  least one  of the
Investor Directors will be  required for the Board  of Directors to approve  and
authorize  certain corporate actions. Such  actions include, without limitation,
the following: (i)  the entry by  Immunex or  any of its  subsidiaries into  any
merger or consolidation or the acquisition by Immunex or any of its subsidiaries
of any business or assets that would constitute more than 10% of the fair market
value of the total assets of Immunex and its subsidiaries; (ii) the sale, lease,
pledge,  grant of security  interest in, license, transfer  or other disposal by
Immunex or any of its subsidiaries of more than 10% of the fair market value  of
the total assets of Immunex and its subsidiaries; (iii) with certain exceptions,
the  issuance of any debt or equity securities or other capital stock of Immunex
or any of its subsidiaries; (iv) a reclassification, split, redemption or  other
acquisition  of any of  the debt or equity  securities of Immunex  or any of its
subsidiaries (subject to certain exceptions); (v) any amendment to the  Articles
of  Incorporation or Bylaws of Immunex or  any change in the size or composition
of the Board of  Directors or committee thereof,  except in accordance with  the
Governance  Agreement; (vi) the  establishment of any committee  of the Board of
Directors not  specifically described  in the  Governance Agreement;  (vii)  any
change   in  accounting  policies  or  procedures  of  Immunex  or  any  of  its
subsidiaries; (viii)  the  payment  or  discharge of  any  claim,  liability  or
obligation  other than  in the  ordinary course  of business,  except where such
claim, liability or obligation does  not exceed $350,000; (ix) the  commencement
or termination of any suit, litigation or

                                       11
<PAGE>
proceeding  with respect  to patent  rights, and  any other  suit, litigation or
proceeding that involves a claim, liability or obligation in excess of  $350,000
or  that is material to Immunex's business  or assets; (x) any (a) incurrence of
indebtedness for borrowed money other than  as provided for in Immunex's  annual
operating plans (the "Annual Operating Plans") provided to Cyanamid from time to
time  or (b) capital expenditure  by Immunex or any  of its subsidiaries that is
greater than both (1) $350,000 and (2) the amount provided for such  expenditure
in  the Annual Operating  Plans; (xi) the  institution by Immunex  or any of its
subsidiaries of any shareholder rights plan or similar plan or device; (xii) the
acquisition by Immunex  or any  of its  subsidiaries of  technology or  products
under any license or similar arrangement if the payments under all such licenses
that  are not  contingent upon  sales of  licensed technology  or products would
exceed $500,000 during any year; or (xiii) the dissolution of Immunex or any  of
its  subsidiaries, the adoption of  a plan of liquidation  for Immunex or any of
its subsidiaries  and  any action  by  Immunex or  any  of its  subsidiaries  to
commence any bankruptcy or similar proceeding.

    The  approval of seven directors (or, if  the Board of Directors consists of
more than nine  persons, that  number of directors  that represents  70% of  the
total  number of directors, rounded up  to the nearest whole number), including,
in the case of  clause (iv) below, two  Independent Directors, will be  required
for  the Board of Directors to approve  any of the following: (i) the employment
of the chief executive officer, chief operating officer, chief financial officer
or chief scientific officer of Immunex  (each, a "Senior Officer"); (ii)  Annual
Operating  Plans  for  Immunex and  its  subsidiaries, which  shall  include all
material capital  expenditures and  borrowing plans  applicable to  the year  in
question;  (iii) Immunex's five-year product development and facility plans; and
(iv) amendment of the Governance  Agreement or provisions of Immunex's  Articles
of  Incorporation  or  Bylaws  implementing  the  provision  of  the  Governance
Agreement.

    The approval of six directors, which six directors must include each of  the
Independent Directors, will be required to approve and authorize the termination
of any Senior Officer.

    SUBSCRIPTION RIGHTS OF CYANAMID

    So  long  as Cyanamid  has  the right  to  designate at  least  one Investor
Director, prior  to any  issuance of  securities by  Immunex, Cyanamid  must  be
offered  the right  to purchase  a pro  rata share  of such  new securities. The
foregoing right does not apply, however,  to securities issued upon exercise  of
outstanding  options or warrants and to certain other issuances specified in the
Governance Agreement.

    So long  as  Cyanamid has  the  right to  designate  at least  one  Investor
Director,  Cyanamid has the option to purchase from Immunex on a quarterly basis
additional shares of Common Stock or other voting stock of Immunex to the extent
necessary to permit  Cyanamid to  maintain the  percentage of  shares of  Common
Stock  or other voting stock  of Immunex, as the case  may be, owned by Cyanamid
and its  affiliates as  of  the immediately  preceding  quarter. The  per  share
purchase  price of such shares of Common Stock or other voting stock of Immunex,
as the case may be, will be equal to the fair market value of such shares on the
date of Cyanamid's purchase.

    STANDSTILL PROVISIONS

    Cyanamid has agreed, until June  1, 1998 (the "Standstill Period"),  subject
to  certain  exceptions, not  to directly  or  indirectly purchase  or otherwise
acquire, or  propose or  offer  to purchase  or  otherwise acquire,  any  equity
securities  of  Immunex,  whether  by  tender  offer,  market  purchase, private
negotiated  purchase,  Business  Combination  (as  defined  in  the   Governance
Agreement  and described below) or otherwise if, immediately after such purchase
or acquisition, Cyanamid's beneficial interest in Immunex would exceed 53.5%  on
a fully diluted basis.

    The  prohibitions on Cyanamid's acquisition  of equity securities of Immunex
do not  apply during  any period  in which  Cyanamid or  any of  its  affiliates
beneficially owns, in the aggregate, less than 5% of the then-outstanding shares
of  Common  Stock (assuming  exercise or  conversion of  any rights,  options or
warrants to  purchase Common  Stock held  by Cyanamid  and its  affiliates,  but
assuming no

                                       12
<PAGE>
other  exercise  or conversion  of outstanding  rights,  options or  warrants to
purchase Common Stock). In addition, such prohibitions do not apply with respect
to any of the following: (i)  any Permitted Acquisition Transaction (as  defined
in  the Governance Agreement and described below) that is disclosed to the Board
of Directors  promptly  after  the  decision  has  been  made  to  propose  such
transaction; (ii) any issuance of securities pursuant to Cyanamid's subscription
rights  set forth in the Governance  Agreement; (iii) open-market purchases made
by Cyanamid from time to time of equity securities of Immunex if (a) immediately
after any such market purchases, Cyanamid's beneficial interest in Immunex would
not exceed 70%  and (b) Cyanamid's  intention to make  such market purchases  is
disclosed  to the Board  of Directors and  shareholders of Immunex  at least two
trading days prior to any such purchases and such purchases are completed within
30 days  of such  notice; and  (iv) any  cash tender  offer by  Cyanamid or  any
affiliate  of  Cyanamid  if,  immediately after  such  tender  offer, Cyanamid's
beneficial interest in Immunex would not exceed 70%.

    Cyanamid has agreed  that, during the  Standstill Period, it  will not,  and
will  not permit its subsidiaries to: (i) after submitting a definitive proposal
for a Permitted  Acquisition Transaction  to the  Board of  Directors, make  any
public  announcement with respect to such transaction without the prior approval
of the Board of Directors, except as  required by law; (ii) make or  participate
in any "solicitation" of "proxies" (as such terms are used in the proxy rules of
the  Securities and Exchange  Commission (the "Commission")) to  vote or seek to
advise, encourage or influence any person  or entity with respect to the  voting
of any shares of capital stock of Immunex; or (iii) deposit any shares of Common
Stock  into  a  voting  trust or  subject  any  shares of  Common  Stock  to any
arrangement or agreement with respect to the voting of such securities or  form,
join  or in any  way participate in  any "group" (within  the meaning of Section
13(d)(3) of the Exchange Act) with respect to any shares of Common Stock.

    A  "Permitted  Acquisition  Transaction,"  as  defined  in  the   Governance
Agreement, means either (i) a cash tender offer for all outstanding Common Stock
that  is conditioned upon approval by at least a majority of the shareholders of
Immunex other than Cyanamid and its affiliates (the "Unaffiliated Shareholders")
or (ii) a Business Combination that is  conditioned upon approval by at least  a
majority  of the Unaffiliated Shareholders, and that satisfies all the following
conditions: (a) the  Board of Directors  receives an opinion  from a  nationally
recognized  independent  investment  banking  firm  selected  by  the  Board  of
Directors (excluding the Investor Directors) that the price and other  financial
terms  of  the  transaction are  fair  from a  financial  point of  view  to the
Unaffiliated Shareholders; (b) the  Board of Directors,  in accordance with  the
Governance   Agreement,  concludes  that  the  price  and  other  terms  of  the
transaction  are  fair  to  and  in  the  best  interests  of  the  Unaffiliated
Shareholders and recommends that the Unaffiliated Shareholders accept the tender
offer  or otherwise  approve the  transaction; and  (c) neither  such investment
banking firm's opinion  nor such  recommendation of  the Board  of Directors  is
withdrawn  prior to the  consummation of the transaction.  In addition, a merger
following the consummation  of a tender  offer described in  clause (i) of  this
paragraph  that offers the same consideration as  such tender offer is deemed to
be a Permitted Acquisition Transaction.

    The term "Business  Combination," as  defined in  the Governance  Agreement,
means  any one of the following transactions: (i) any merger or consolidation of
Immunex or any subsidiary  of Immunex with (a)  Cyanamid or (b) any  corporation
(other  than Immunex) which is, or after  such merger or consolidation would be,
an affiliate or  associate of  Cyanamid; (ii) any  tender or  exchange offer  by
Cyanamid  or any affiliate or associate of Cyanamid for any equity securities of
Immunex or any of its subsidiaries;  (iii) any sale, lease, exchange,  mortgage,
pledge, transfer or other disposition by Immunex (in one transaction or a series
of  transactions) to or with Cyanamid or  any affiliate or associate of Cyanamid
(other than Immunex)  of more than  10% of the  fair market value  of the  total
assets of Immunex and its subsidiaries; (iv) the issuance, exchange or transfer,
other  than  pursuant to  Cyanamid's  subscription rights  under  the Governance
Agreement, by Immunex or any of its subsidiaries (in one transaction or a series
of transactions)  of any  securities of  Immunex or  any subsidiary  thereof  to
Cyanamid  or  any affiliate  or associate  of Cyanamid  (other than  Immunex) in
exchange for cash, securities or other consideration (or a combination  thereof)
having an aggregate fair market value

                                       13
<PAGE>
equal  to or in excess  of 10% of the  fair market value of  the total assets of
Immunex and its subsidiaries; (v) the adoption  of any plan or proposal for  the
liquidation  or dissolution of Immunex  proposed by or on  behalf of Cyanamid or
any affiliate  or  associate of  Cyanamid  (other  than Immunex);  or  (vi)  any
reclassification   of   securities   (including   any   reverse   stock  split),
recapitalization of Immunex, or any merger or consolidation of Immunex with  any
subsidiary  thereof,  or  any other  transaction  to  which Immunex  is  a party
(whether or not with or into or otherwise involving Cyanamid or any affiliate or
associate  of  Cyanamid)  that  has  the  effect,  directly  or  indirectly,  of
increasing  the proportionate  share of the  outstanding shares of  any class of
equity or convertible securities of Immunex  or any subsidiary thereof which  is
directly  or  indirectly owned  by  Cyanamid or  any  affiliate or  associate of
Cyanamid (other than Immunex).

    MATERIAL TRANSACTIONS WITH CYANAMID

    Immunex may  not enter  into  any contract,  agreement or  transaction  with
Cyanamid  or any of its affiliates that is material to Immunex's business, taken
as a whole, unless two-thirds  of the members of  the Board of Directors,  other
than  the Investor Directors  and including at  least two Independent Directors,
approve such contract, agreement or transaction.

    TRANSFER OF IMMUNEX COMMON STOCK BY CYANAMID

    Cyanamid has agreed  that, during the  Standstill Period, it  will not,  and
will  not  permit any  entity that  is  directly or  indirectly wholly  owned by
Cyanamid to,  transfer any  shares of  Common Stock,  except (i)  pursuant to  a
registered  underwritten  public offering  in  accordance with  the registration
rights provisions  of the  Governance  Agreement, (ii)  in accordance  with  the
volume  and  manner  of  sale  limitations of  Rule  144  promulgated  under the
Securities Act  of 1933,  as amended  (the "Securities  Act"), or  (iii) to  any
wholly  owned subsidiary of Cyanamid. During the Standstill Period, Cyanamid may
not transfer any interest in any Common Stock to any purchaser or group  (within
the  meaning of Section  13(d)(3) of the  Exchange Act) of  purchasers if, after
giving effect to  such sale,  such purchaser or  group of  purchasers would,  to
Cyanamid's  knowledge, own,  or have  the right  to acquire,  5% or  more of the
then-outstanding shares of Common Stock. Other than through a block trade in  an
underwritten  offering,  Cyanamid  may  not,  directly  or  through  any  of its
subsidiaries, transfer any interest  in shares of Common  Stock in excess of  1%
per day of the then-outstanding shares of Common Stock.

    Notwithstanding  the foregoing paragraph,  after June 1,  1996, Cyanamid and
its wholly owned subsidiaries may transfer (an "Acquisition Sale") all (but  not
less  than all)  the shares of  Common Stock  beneficially owned by  them to any
other person  other than  an affiliate  of Cyanamid,  provided that  such  other
person has offered to acquire all outstanding shares of Common Stock on the same
terms  and conditions as such Acquisition Sale. In addition, if Cyanamid intends
to engage in an Acquisition Sale it is required to notify Immunex of such intent
and, for  three  months  subsequent  to  such  notice,  Immunex  will  have  the
opportunity  to present  to Cyanamid a  potential buyer willing  to purchase all
(but not  less  than all)  the  shares of  Common  Stock beneficially  owned  by
Cyanamid  and its wholly owned subsidiaries. In the event that a potential buyer
is presented, Cyanamid  may not  consummate an  Acquisition Sale  on terms  less
favorable to Cyanamid than those proposed by such potential buyer.

    During  the Standstill Period, Cyanamid may  not sell, transfer or otherwise
dispose of any of the capital stock  of any wholly owned subsidiary of  Cyanamid
that owns Common Stock, except to another wholly owned subsidiary of Cyanamid.

    REGISTRATION RIGHTS

    The holders of at least 25% of the Registrable Securities (as defined in the
Governance Agreement) (the "Initiating Holders") may request that Immunex file a
registration statement under the Securities Act covering the registration of any
or  all Registrable Securities held by such Initiating Holders. Immunex will not
be obligated  to  effect  more  than  two  such  registrations.  The  Governance
Agreement,  however, does not limit the number of registrations on Form S-3 that
may be requested

                                       14
<PAGE>
and obtained if Immunex is eligible to use Form S-3, provided that the estimated
aggregate  offering  price  to the  public  exceeds  $25 million  and  the other
provisions of the Governance Agreement are satisfied.

    Subject to certain conditions,  if Immunex proposes  to file a  registration
statement  under the Securities Act on any form  (other than on Form S-4 or S-8)
that also  would permit  the registration  of Registrable  Securities, and  such
filing  is to be on  behalf of Immunex or selling  holders of its securities for
the general registration of shares of  Common Stock for cash, Immunex must  give
notice thereof to the holders of the registration rights and permit such holders
to include Registrable Securities in the registration.

    Cyanamid's  registration rights are subject  to certain conditions set forth
in the Governance Agreement.  In addition, the  Governance Agreement sets  forth
specific   procedures  relating   to  such  registration   rights  and  detailed
obligations of the parties  with respect thereto. All  expenses incident to  the
performance  by Immunex of  its obligations with respect  to the registration of
Cyanamid's shares of  Common Stock  will be borne  by Immunex,  except that  the
Initiating Holders will pay all expenses incident to the second registration. In
addition,   the  holders  of  Registrable  Securities  will  bear  and  pay  the
underwriting commissions  and discounts  applicable  to securities  offered  for
their  account in connection with  any registrations, filings and qualifications
made pursuant to  the Governance  Agreement, as  well as  related counsel  fees.
Immunex  and the holders of Registrable Securities each have agreed to indemnify
the other,  in  certain  instances,  with respect  to  liabilities  incurred  in
connection with such registrations.

    GUARANTY PAYMENTS BY CYANAMID

    Until  December 31,  1997, Cyanamid has  agreed to make  certain payments to
Immunex if revenues from products of  the Lederle Oncology Business and  certain
other products of Immunex do not achieve certain annual targets. The targets for
1995  through 1997 are  listed below as "Target  Revenue." Payments are required
for any calendar  year in  which Target  Revenue exceeds  the "Actual  Revenue,"
i.e.,  the sum of Immunex's net sales of Lederle Oncology Products, New Oncology
Products  and  Additional  Products  plus  certain  other  revenues  related  to
Additional Products (as such terms are described below).

    The  payment for any year in which Target Revenue is not realized equals (i)
the amount by which Target Revenue for the calendar year exceeded Actual Revenue
for such year (a "Revenue Shortfall") reduced by (ii) the total of the following
costs  for  such  year  ("Avoided  Costs"):  (a)  variable  manufacturing  costs
(including  packaging and similar  costs); (b) variable  distribution costs; (c)
commissions; (d) royalties and similar fees  paid to third parties; and (e)  all
costs  for  advertising, promotion,  marketing, distribution  or selling  of any
Product (as described below) that were contemplated in the Annual Operating Plan
for such year  that were  not incurred because  any approval  required for  such
Product  or  any new  label indication  therefor  was not  received by  the date
contemplated by  such  Annual  Operating Plan  ("Avoided  Introductory  Costs").
Notwithstanding  the  foregoing,  the  Revenue  Shortfall  may  not  exceed  the
difference between the Target Revenue and  the Base Revenue set forth below  and
Cyanamid's  payment obligation  may not  exceed the  amounts set  forth below as
"Cyanamid's Maximum Obligation." Immunex recorded a receivable from Cyanamid  of
$35,768,000  for the  Revenue Shortfall for  1994. Cyanamid paid  this amount in
March 1995.

<TABLE>
<CAPTION>
                                                                  1995    1996    1997
                                                                 ------  ------  ------
                                                                     (IN MILLIONS)
<S>                                                              <C>     <C>     <C>
Target Revenue.................................................  $168.6  $190.5  $216.5
Base Revenue...................................................   102.0   103.0   122.7
Maximum Revenue Shortfall......................................    66.6    87.5    93.8
Cyanamid's Maximum Obligation..................................    45.3    56.0    60.0
</TABLE>

    For purposes of  calculating Cyanamid's payment  obligations, Avoided  Costs
may  not exceed  15% of  any Revenue Shortfall  in 1995  and 20%  of any Revenue
Shortfall in each of 1996 and 1997;  provided, however, that in the event  total
Avoided Costs exceed such ceilings, Cyanamid may reduce

                                       15
<PAGE>
its  Revenue Shortfall obligation by the  amount of such excess that constitutes
Avoided Introductory Costs. Cyanamid may reduce its Revenue Shortfall obligation
for 1997 by any amount  by which Actual Revenue  exceeded Target Revenue in  any
prior calendar year.

    Subject  to certain conditions, Cyanamid may discharge its Revenue Shortfall
obligation otherwise than  by payment of  the applicable cash  amount under  the
Governance  Agreement if  such alternative  consideration provides  Immunex with
equivalent value.

    The term "Cyanamid Oncology Products" is defined in the Governance Agreement
to mean NOVANTRONE  mitoxantrone, methotrexate  injectable, leucovorin  calcium,
thiotepa,  AMICAR  aminocaproic  acid,  LEVOPROME  methotrimeprazine, Cyanamid's
generic anticancer products that are  the subject of filings seeking  regulatory
approval  and photodynamic therapy compounds and  related devices. The term "New
Oncology Products" means all oncology products useful (to the extent useful)  in
the  diagnosis  or  treatment  of  cancerous  or  precancerous,  transitional or
neoplastic diseases or conditions in humans resulting from research conducted by
Cyanamid, the  Company,  or  research  jointly sponsored  by  Cyanamid  and  the
Company,  or any  such product  with respect  to which  Cyanamid or  the Company
(except for any such product that  is acquired solely through the Company's  own
efforts)  is  the licensee  or distributor  (to  the extent  of such  license or
distribution rights) or is  otherwise subsequently acquired  by Cyanamid or  the
Company,    including,   without    limitation:   (i)    cytotoxics   (including
photosensitizers) and  cytokine modulators;  (ii) small  molecule  hematopoietic
stimulators;  (iii) cytokines and cytokine  receptors; (iv) MDR reversal agents;
(v) anti-tumor monoclonal antibody conjugates; (vi) RAS pathway antagonists; and
(vii) receptors  other  than  TNFR.  New Oncology  Products  will  exclude  such
products  to the extent that the Company or Cyanamid cannot grant license rights
to the other due  to preexisting agreements entered  into prior to December  15,
1992.  Should  either party,  however, have  those rights  returned to  it, such
product will  immediately  become  a  New  Oncology  Product.  For  purposes  of
determining Actual Revenues only, New Oncology Products will exclude any product
of  Immunex that was marketed, clinically tested or in preclinical testing as of
the Effective Time. The term "Additional Products" is defined in the  Governance
Agreement  to mean such  additional products designated (on  an annual basis) by
Cyanamid, with the concurrence of the Board of Directors, that are not  Cyanamid
Oncology Products, New Oncology Products or Copromoted Products from which sales
or  copromotion revenues  are to  be included  in Immunex's  consolidated income
statements by  reason of  the fact  that the  Annual Operating  Plan of  Immunex
forecasts  a Revenue  Shortfall in  respect of  Cyanamid Oncology  Products, New
Oncology Products and Copromoted Products. The term "Products" is defined in the
Governance Agreement to mean, in the aggregate, Cyanamid Oncology Products,  New
Oncology Products and Additional Products.

    TERMINATION

    The  Governance Agreement will terminate at the  earlier of (i) such time as
Cyanamid and its affiliates  beneficially own 95% of  all classes and series  of
Common Stock and (ii) such time as Cyanamid and its affiliates no longer own any
such shares.

RESEARCH AND DEVELOPMENT AGREEMENT

    In  connection with the Merger, Cyanamid and Immunex entered into a Research
and Development  Agreement  (the  "Research and  Development  Agreement")  under
which,  among  other  things,  the  parties  collaborate  in  the  research  and
development and commercialization of New Oncology Products. Cyanamid and Immunex
formed a Collaboration Committee, which is responsible for planning, supervising
and coordinating  the collaborative  development  and commercialization  of  New
Oncology  Products.  During  the  years 1993  through  1997,  Immunex  agreed to
contribute certain  amounts  in  support of  Cyanamid's  oncology  research  and
development  programs, within  certain limits. During  1994, Immunex contributed
$15,300,000, and during the years 1995  through 1997, Immunex has agreed to  pay
the  amounts  shown below  as Immunex  Contribution. To  the extent  that actual
Cyanamid oncology  research and  development expenses  for any  year exceed  the
Total Oncology

                                       16
<PAGE>
Research and Development Budget Amount shown below, Immunex will also pay 50% of
such excess, provided that any such excess greater than 3% of the Total Oncology
Research  and Development Budget Amount shown below  is approved by the Board of
Directors.

<TABLE>
<CAPTION>
                                                                     1995   1996   1997
                                                                     -----  -----  -----
                                                                        (IN MILLIONS)
<S>                                                                  <C>    <C>    <C>
Total Oncology Research and Development
  Budget Amount....................................................  $63.3  $69.6  $76.6
Immunex Contribution...............................................   15.8   26.1   38.3
</TABLE>

    After 1997, Immunex has agreed to contribute 50% of the funding budgeted for
Cyanamid's oncology discovery research program.  Immunex and Cyanamid each  will
bear  development costs relating to each New Oncology Product to the extent such
costs relate  to  approval  to sell  such  product  in the  United  States,  its
territories  and possessions  and Canada, in  the case of  Immunex (the "Immunex
Territory"), or in all  other countries of  the world, in  the case of  Cyanamid
(the "Cyanamid Territory").

    Cyanamid  granted  to Immunex  a  royalty-free exclusive  license  under all
patents and technology owned or controlled by Cyanamid relating to New  Oncology
Products  to make,  have made,  use and  sell all  New Oncology  Products in the
Immunex Territory, subject to Cyanamid's retained  right to make, have made  and
use  New Oncology Products  in the Immunex Territory.  In addition, Cyanamid and
Immunex each granted  to the  other a  royalty-free exclusive  license to  their
respective  portions of any jointly owned technology to make, have made, use and
sell such technology in the Cyanamid Territory or the Immunex Territory, as  the
case may be. Immunex and Cyanamid have agreed to cooperate in preparing, filing,
maintaining   and  defending  all  such  patents  and  in  protecting  all  such
technology, in each  case relating to  the New Oncology  Products. In the  event
that  a New Oncology Product is to be manufactured by Cyanamid for Immunex or by
Immunex for  Cyanamid,  the  manufacturing  party  will  supply  the  reasonable
clinical and commercial requirements of the other party for such product under a
supply agreement to be entered into by Immunex and Cyanamid, at a cost that will
reimburse  the  manufacturing party  for its  manufacturing and  (within certain
limits) process  development  costs (including  an  allocation for  general  and
administrative   costs)  allocable  to  such  product,  plus,  with  respect  to
commercial requirements, a  reasonable profit.  To the  extent Immunex  develops
products  or technology other  than New Oncology Products  and determines not to
market such  products  or technology  itself,  Immunex will  offer  to  Cyanamid
exclusive  marketing rights to  any such products  or technology before offering
any marketing rights to third parties.

    If Cyanamid were to own  less than 50% of  the Common Stock, Cyanamid  would
have  the right to terminate the Research  and Development Agreement on 60 days'
notice.

ONCOLOGY PRODUCT LICENSE AGREEMENT

    In connection with the Merger, Cyanamid and Immunex entered into an Oncology
Product License Agreement under which Immunex granted to Cyanamid and certain of
its subsidiaries an exclusive license under the patents and know-how acquired by
Immunex to  make, have  made and  use Contributed  Lederle Products  other  than
Distributed  Products (the "Assigned Products"),  thereby permitting Cyanamid to
manufacture the Assigned Products in the Immunex Territory for supply to Immunex
and for  ultimate  sale  by  Cyanamid  and  its  sublicensees  in  the  Cyanamid
Territory.  Cyanamid pays to Immunex  a royalty equal to 5%  of the net sales by
Cyanamid of the Assigned Products manufactured in the Immunex Territory and sold
in the Cyanamid  Territory. Immunex  and Cyanamid  have agreed  to cooperate  in
preparing,  filing, maintaining and defending all patents, and in protecting all
technology, relating to Assigned Products. Immunex recognized revenue under this
agreement of $2,571,000 during 1994.

IMMUNEX NEW ONCOLOGY PRODUCT LICENSE AGREEMENT

    Cyanamid and  Immunex have  entered  into an  Immunex New  Oncology  Product
License  Agreement (the "Immunex New  Oncology Product License Agreement") under
which Immunex granted to Cyanamid a co-exclusive license to make, have made, use
and sell in the Cyanamid Territory New

                                       17
<PAGE>
Oncology Products resulting from the research and development efforts of Immunex
("Immunex New Oncology Products"). Cyanamid pays  to Immunex a royalty equal  to
5%  of the net sales of Immunex  New Oncology Products in the Cyanamid Territory
by Cyanamid. Immunex  and Cyanamid cooperate  in preparing, filing,  maintaining
and  defending  all patents,  and  in protecting  all  technology, in  each case
relating to  the  Immunex New  Oncology  Products  covered by  the  Immunex  New
Oncology  Product License Agreement.  In the event that  an Immunex New Oncology
Product is  to  be manufactured  by  Immunex for  Cyanamid  or by  Cyanamid  for
Immunex,  the manufacturing party  has agreed to  supply the reasonable clinical
and commercial requirements of the other  party for such product under a  supply
agreement  to be  entered into  by Immunex  and Cyanamid,  at a  price that will
reimburse the manufacturing party for its manufacturing and process  development
costs  (including an allocation for  general and administrative costs) allocable
to such product,  plus, with  respect to commercial  requirements, a  reasonable
profit. Immunex recognized revenue under this agreement of $327,000 during 1994.

TRADEMARK LICENSE AGREEMENT

    Cyanamid  and Immunex  have entered into  a United  States Trademark License
Agreement under which Cyanamid  granted to Immunex an  exclusive license in  the
United  States  to  use certain  trademarks  in connection  with  the marketing,
distribution and sale of the Lederle Oncology Products in the Immunex Territory.
In consideration  for the  grant of  such  license, Immunex  has agreed  to  pay
Cyanamid  a royalty equal to 2%  of the net sales by  Immunex of products in the
Immunex Territory that are sold using the trademarks. The royalties incurred  by
Immunex during 1994 totaled $1,702,000.

SUPPLY AGREEMENT, TOLL MANUFACTURING AGREEMENT AND METHOTREXATE DISTRIBUTORSHIP
AGREEMENT

    In  connection with the  Merger, Cyanamid and Immunex  entered into a Supply
Agreement, under  which  Cyanamid agreed  to  supply the  reasonable  commercial
requirements  of  Immunex, subject  to specific  maximum quantities,  for AMICAR
aminocaproic acid, oral formulations  of leucovorin calcium (currently  marketed
forms  only), and thiotepa (currently  marketed forms only) at  a price equal to
125% of Cyanamid's  manufacturing costs (including  reasonable overhead  charges
and  certain other costs)  for such products.  In addition, Lederle Parenterals,
Inc.  ("LPI"),  a  subsidiary  of   Cyanamid  that  operates  a   pharmaceutical
manufacturing   facility  in   Carolina,  Puerto  Rico,   and  Immunex  Carolina
Corporation ("ICC"), a subsidiary  of Immunex that manufactured  pharmaceuticals
in  Puerto Rico in 1994, have entered  into a Toll Manufacturing Agreement under
which  LPI  toll  converts  raw  materials  provided  by  ICC  into   injectable
formulations of NOVANTRONE mitoxantrone, leucovorin calcium, AMICAR aminocaproic
acid  and LEVOPROME methotrimeprazine  at a price  equal to 125%  of LPI's costs
relating to such  toll conversion. ICC  was dissolved in  December 1994 and  its
rights under the Supply Agreement were assigned to Immunex. LPI and Immunex have
also  entered into a Methotrexate Distributorship Agreement whereby LPI supplies
methotrexate to Immunex at  prices that are adjusted  annually. Immunex and  ICC
purchased  inventory at a cost of $10,062,000  from Cyanamid and LPI under these
agreements during 1994.

SERVICES AGREEMENT

    Cyanamid and Immunex have  entered into a  United States Services  Agreement
(the  "Services  Agreement") under  which Cyanamid  may provide  certain medical
support,   government   sales,   sales,   education,   pricing   and    contract
administration,   market  research,  industry  affairs,  advertising  and  sales
promotion, warehousing, distribution, credit  and collections, legal and  merger
transition  services to Immunex. As Immunex progressively assumes responsibility
for such services,  Immunex will  have the  right to  terminate its  obligations
under  the Services  Agreement, on a  function-by-function basis,  on 12 months'
notice to Cyanamid. Immunex incurred  costs totaling $6,759,000 under the  terms
of  this  agreement  during  1994.  Cyanamid  also  incurred  certain additional
expenses not included in the service  fees for which Immunex agreed to  directly
reimburse Cyanamid. These expenses totaled $893,000 during 1994.

                                       18
<PAGE>
DISTRIBUTORSHIP AGREEMENT FOR CANADA

    Cyanamid  Canada, Inc. ("Cyanamid  Canada") and Immunex  have entered into a
distributorship agreement under which Immunex  appointed Cyanamid Canada as  its
distributor  in  Canada  for  certain products.  Immunex  agreed  to  supply the
products to Cyanamid  Canada at established  prices that are  subject to  annual
adjustment. Immunex sold $1,946,000 of inventory to Cyanamid Canada during 1994.

LOAN AGREEMENT

    Immunex and Cyanamid Agricultural de Puerto Rico, Inc. ("CAPRI"), a Cyanamid
subsidiary,  entered into  a Loan Agreement  in September 1993  (as amended, the
"Loan Agreement"). Pursuant  to the  Loan Agreement,  CAPRI has  agreed to  lend
Immunex  up to  the lesser of  $50 million or  110% of the  amount receivable by
Immunex from Cyanamid under the revenue guaranty for working capital purposes on
a revolving credit basis. Interest accrues on outstanding balances at LIBOR plus
1% and  is payable  on maturity  of individual  borrowings. Unless  extended  by
mutual  agreement, the Loan Agreement expires on  March 31, 1996. As of December
31, 1994, Immunex had borrowed $34 million under the Loan Agreement. This amount
was repaid in March 1995.

                               EXECUTIVE OFFICERS

    The following individuals  are executive  officers of the  Company who  will
serve  in the capacities noted  until April 26, 1995,  or until the election and
qualification of their successors.  Each officer named below  is expected to  be
reelected  at the Company's Board  of Directors meeting to  be held on April 26,
1995.

<TABLE>
<CAPTION>
                                                                                                                 OFFICER
           NAME                AGE                     POSITIONS AND OFFICES WITH THE COMPANY                     SINCE
--------------------------     ---     -----------------------------------------------------------------------  ---------
<S>                         <C>        <C>                                                                      <C>
Edward V. Fritzky              44      Chief Executive Officer                                                    1994
Michael L. Kranda              41      President; Chief Operating Officer                                         1988
Scott G. Hallquist             41      Senior Vice President; Secretary; General Counsel                          1987
Peggy V. Phillips              41      Senior Vice President, Pharmaceutical Development                          1995
Douglas G. Southern            52      Senior Vice President; Chief Financial Officer; Treasurer                  1991
Leonard R. Stevens             45      Senior Vice President, Strategic and New Product Planning                  1993
Douglas E. Williams            36      Senior Vice President, Discovery Research                                  1995
David L. Urdal                 45      Senior Vice President, Manufacturing and Process Sciences                  1990
</TABLE>

    For the biographical summaries of Messrs. Fritzky and Kranda, see  "Election
of Directors."

    Mr. Hallquist has been employed by the Company since June 1986, initially as
Director, Legal Affairs. He was elected to serve as Secretary in May 1987 and as
Vice  President and General  Counsel in January 1989.  Mr. Hallquist was elected
Senior Vice President in October 1990, retaining the offices of General  Counsel
and  Secretary. Prior to joining the Company, he was employed by E.I. du Pont de
Nemours and Company as  patent counsel. Mr. Hallquist  received M.B.A. and  J.D.
degrees  from  the University  of North  Carolina  in 1981.  Mr. Hallquist  is a
director  of  Qual-Med  Washington  Health  Plan,  Inc.,  a  health  maintenance
organization and subsidiary of Health Systems International, Inc.

    Ms.  Phillips joined the  Company in 1986, was  named Senior Vice President,
Pharmaceutical Development  in  September 1994,  and  was elected  an  executive
officer  of the  Company in  February 1995. From  1991 until  its dissolution in
January 1995,  Ms.  Phillips had  served  as  Senior Vice  President  and  Chief
Operating  Officer of IRDCO, the Company's wholly owned research and development
corporation. Ms. Phillips received an  M.S. in microbiology from the  University
of Idaho.

    Mr.  Southern has  been Senior Vice  President, Chief  Financial Officer and
Treasurer of the Company since January  1991. Prior to joining the Company,  Mr.
Southern  was  employed  as  Senior  Vice  President,  Chief  Financial Officer,
Treasurer   and   Secretary   of   Pay   'N   Pak   Stores,   Inc.   ("Pay    'N

                                       19
<PAGE>
Pak"), a retail firm headquartered in Seattle, Washington. Mr. Southern resigned
from  Pay 'N Pak in June 1990. Pay  'N Pak filed for protection under Chapter 11
of the Federal Bankruptcy Code on September 21, 1991.

    Mr. Stevens joined the Company in July 1993 as Vice President, Strategic and
New Product Planning, and was elected Senior Vice President in 1994. Mr. Stevens
had been employed by Lederle Laboratories  since December 1989, where he  served
in  several capacities,  including Director  of Medical  Education and Programs,
Director of Professional Education and Director of Oncology Marketing, prior  to
being  appointed as Vice President and General Manager of Oncology in June 1992.
Mr. Stevens was  an Account Supervisor  for Klemtner Advertising  from April  to
December  1989.  He was  employed by  Alcide  Corporation, an  animal healthcare
products company, as Vice President of Sales and Marketing from October 1988  to
April 1989, after being employed by G.D. Searle for over 10 years, most recently
as  Director, Marketing.  Mr. Stevens received  an M.B.A from  the University of
Pittsburgh in 1977.

    Dr. Williams joined  the Company  in 1988. He  served as  Vice President  of
Research  and Development from 1992 until  September 1994, when he was appointed
to his  current  position of  Senior  Vice President,  Discovery  Research.  Dr.
Williams  was elected an executive  officer of the Company  in February 1995. He
received a Ph.D. in physiology from the State University of New York at Buffalo,
Roswell Park Memorial Institute Division.

    Dr. Urdal has been  employed by the Company  since 1982, initially as  Staff
Scientist.  In 1983, Dr.  Urdal was promoted  to Senior Staff  Scientist and, in
1986, to Vice President and Assistant  Director of Research and Development.  In
1988,  Dr. Urdal was appointed Director of Development and became Vice President
of Immunex Research and Development Corporation upon its incorporation in  1989.
In  1990, Dr. Urdal  was elected President  of Immunex Manufacturing Corporation
and in  February 1995  he was  named Senior  Vice President,  Manufacturing  and
Process  Sciences, of the  Company. During the period  from September 1993 until
Mr. Fritzky's election in January  1994, Dr. Urdal served  as a director of  the
Company.  Dr. Urdal received  a Ph.D. in  biochemical oncology in  1980 from the
University of Washington.

                             EXECUTIVE COMPENSATION

COMPENSATION SUMMARY

    The following table sets forth certain  information as to (i) the  Company's
chief  executive officer, (ii) the Company's  four other most highly compensated
executive officers, and (iii) Dr. Gillis, who served as the Company's  Executive
Vice  President  and  Chief  Scientific  Officer  prior  to  his  resignation on
September 29, 1994,  for services  rendered in  all capacities  for the  Company
during the fiscal years ended December 31, 1994, 1993 and 1992.

                                       20
<PAGE>
                           SUMMARY COMPENSATION TABLE

<TABLE>
<CAPTION>
                                                                               LONG-TERM
                                                                             COMPENSATION
                                                                                /AWARDS
                                                               ANNUAL        -------------
                                                            COMPENSATION        SHARES        ALL
                                                         ------------------   UNDERLYING     OTHER
NAME AND PRINCIPAL POSITION                     YEAR     SALARY ($) BONUS ($)  OPTIONS (#)  COMPENSATION (1)
--------------------------------------------  ---------  --------  --------  -------------  --------
<S>                                           <C>        <C>       <C>       <C>            <C>
Edward V. Fritzky ..........................       1994  $306,674  $ 79,219       125,000   $523,483
  Chief Executive Officer
Steven Gillis (2) ..........................       1994  $277,096         0             0   $25,084
  Former Executive Vice President; Chief           1993  $350,000  $175,000        40,000   $17,639
  Scientific Officer                               1992  $312,500  $117,188         2,778   $  2,442
Michael L. Kranda ..........................       1994  $288,768  $ 75,797             0   $19,325
  President; Chief Operating Officer               1993  $275,016  $ 88,000        40,000   $13,866
                                                   1992  $220,500  $ 82,688         1,960   $2,392
Scott G. Hallquist .........................       1994  $236,250  $ 67,922             0   $17,258
  Senior Vice President; Secretary;                1993  $225,000  $101,250        40,000   $11,609
  General Counsel                                  1992  $191,750  $ 71,906         1,704   $2,446
David L. Urdal .............................       1994  $203,500  $ 58,506             0   $14,412
  Senior Vice President,                           1993  $185,000  $ 74,000        40,000   $9,658
  Manufacturing and Process                        1992  $163,000  $ 61,125         1,159   $2,590
  Sciences
Douglas G. Southern ........................       1994  $155,820  $ 44,798             0   $9,638
  Senior Vice President; Chief                     1993  $148,400  $ 43,778        30,000   $3,550
  Financial Officer; Treasurer                     1992  $140,000  $ 52,500           996   $3,338
<FN>
------------------------
(1)  Consists  of matching  contributions to  a 401(k)  savings plan  of $6,500,
     $24,572, $18,838, $16,877, $13,877, and  $8,487 and payment of excess  life
     insurance  premiums of $1,584,  $512, $488, $381, $536,  and $1,152 for Mr.
     Fritzky, Dr.  Gillis,  Mr.  Kranda,  Mr.  Hallquist,  Dr.  Urdal,  and  Mr.
     Southern, respectively, in 1994. In addition, for Mr. Fritzky also consists
     of  $515,399 for reimbursement of costs and expenses incurred in connection
     with his relocation to Washington.

(2)  Dr. Gillis resigned as an officer of the Company in September 1994.
</TABLE>

OPTION GRANTS

    The following table sets forth certain information regarding options granted
during the fiscal year ended December 31, 1994 to the Company's chief  executive
officer.  None  of  the other  current  or  former executive  officers  for whom
compensation is reported in this Proxy Statement was granted any options  during
the fiscal year ended December 31, 1994.

                       OPTION GRANTS IN 1994 FISCAL YEAR

<TABLE>
<CAPTION>
                                                                                          POTENTIAL REALIZABLE
                                                   INDIVIDUAL GRANTS                        VALUE AT ASSUMED
                               ---------------------------------------------------------    ANNUAL RATES OF
                                 NUMBER OF      PERCENT OF                                    STOCK PRICE
                                  SHARES       TOTAL OPTIONS                                APPRECIATION FOR
                                UNDERLYING      GRANTED TO       EXERCISE                   OPTION TERM (3)
                                  OPTIONS      EMPLOYEES IN        PRICE      EXPIRATION  --------------------
NAME                            GRANTED (#)     FISCAL YEAR    ($/SHARE) (1)   DATE (2)      5%        10%
-----------------------------  -------------  ---------------  -------------  ----------  --------  ----------
<S>                            <C>            <C>              <C>            <C>         <C>       <C>
Edward V. Fritzky............       50,000             28%     $      13.75    10/20/04   $432,365  $1,095,698
                                    75,000             42%     $      18.88    1/26/04    $890,515  $2,256,939
<FN>
------------------------
(1)  The  exercise price of the options is equal to the fair market value of the
     underlying Common Stock on the date of grant.
</TABLE>

                                       21
<PAGE>
<TABLE>
<S>  <C>
(2)  The options vest  on a  five-year schedule, becoming  fully exercisable  on
     January  26 and October  20, 1999, provided the  holder remains employed by
     the Company. The options terminate 10 years from the date of grant.

(3)  Future value of current year grants assuming appreciation of 5% and 10% per
     year over  the 10-year  option period.  The actual  value realized  may  be
     greater  than or less than the potential realizable values set forth in the
     table.
</TABLE>

OPTION EXERCISES AND YEAR-END VALUES

    The following table sets forth certain  information as of December 31,  1994
regarding  options held by  the Company's chief executive  officer and the other
current and former executive officers for whom compensation is reported in  this
Proxy  Statement. None of such officers  exercised any options during the fiscal
year ended December 31, 1994.

                         FISCAL YEAR-END OPTION VALUES

<TABLE>
<CAPTION>
                                                                                             VALUE OF
                                                               NUMBER OF SECURITIES         UNEXERCISED
                                                              UNDERLYING UNEXERCISED       IN-THE-MONEY
                                                                    OPTIONS AT              OPTIONS AT
                                                               FISCAL YEAR-END (#)      FISCAL YEAR-END ($)
                                                            --------------------------  -------------------
NAME                                                        EXERCISABLE  UNEXERCISABLE  EXERCISABLE UNEXERCISABLE
----------------------------------------------------------  -----------  -------------  ----------  -------
<S>                                                         <C>          <C>            <C>         <C>
Edward V. Fritzky.........................................      --            125,000       0       $56,500
Steven Gillis.............................................      --            --            --        --
Michael L. Kranda.........................................       8,000         32,000       0            0
Scott G. Hallquist........................................       8,000         32,000       0            0
David L. Urdal............................................       8,000         32,000       0            0
Douglas G. Southern.......................................       6,000         24,000       0            0
</TABLE>

EMPLOYMENT AGREEMENTS

    Immunex entered into employment  agreements with Drs.  Gillis and Urdal  and
Messrs.  Hallquist and  Kranda in  connection with  the Merger.  Each employment
agreement became effective  as of  the Effective Time.  Following Mr.  Fritzky's
election  as Chairman, Immunex  entered into a  substantially similar employment
agreement with  Mr. Fritzky  with an  effective date  of January  21, 1994.  The
employment  agreement with Dr. Gillis was  terminated with the mutual consent of
the Company  and  Dr.  Gillis  effective  September  29,  1994.  The  employment
agreements  with  Messrs.  Fritzky,  Hallquist and  Kranda  and  Dr.  Urdal (the
"Employment Agreements") are  effective for  a term  of three  years from  their
effective date. Each Employment Agreement provides that the employee will hold a
position  at  least  commensurate with  that  held  by the  employee  as  of its
effective date. The annual base salary payable to Messrs. Fritzky, Hallquist and
Kranda and  Dr.  Urdal  pursuant  to such  Employment  Agreements  is  $325,000,
$225,000,  $275,000 and $185,000, respectively. Such  annual base salary may not
be reduced during the term of the Employment Agreement. If the employment of the
employee is terminated by the Company without Cause or by the employee for  Good
Reason  (each  as defined  in the  Employment Agreement),  the employee  will be
entitled to receive his base salary  and certain other payments until the  later
of  two years  from the date  his employment was  terminated and the  end of the
three-year term of such Employment Agreement. Dr. Gillis and the Company  agreed
that  termination of the  Employment Agreement with  Dr. Gillis occurred without
Good Reason; accordingly, no  salary or other payments  were made to Dr.  Gillis
that had not accrued prior to termination.

REPORT ON EXECUTIVE COMPENSATION BY THE COMPENSATION COMMITTEE AND THE STOCK
OPTION PLAN ADMINISTRATION COMMITTEE

    The  Company's compensation policy as established  by its Board of Directors
(the "Board") is intended to provide competitive compensation to all  employees,
giving  consideration  to  the  relative contribution  and  performance  of each
individual employee.  It is  the Company's  policy to  compensate its  executive
officers at levels consistent with industry norms, primarily in the form of base
salary,

                                       22
<PAGE>
together  with incentive bonuses of up to  37.5% of base salary. In addition, it
is the  Company's  policy  to grant  stock  options  to each  of  its  executive
officers,  based on individual and Company performance and in amounts consistent
with industry norms, so as to align their interests with shareholder value.  The
biotechnology  industry is extremely competitive with respect to recruitment and
retention of qualified personnel; accordingly, the Company's management  employs
surveys  of  biotechnology  industry  compensation  levels  to  ensure  that the
Company's  compensation  practices   are  comparable   to  other   biotechnology
companies, thereby enabling it to attract and retain key employees.

    Determining  the compensation levels of  the Company's executive officers is
the responsibility of the Board,  through its Compensation Committee, which  has
overall  responsibility  for  the  Company's  compensation  policies  for senior
management, and  its  Stock  Option  Plan  Administration  Committee,  which  is
responsible for administering the Company's stock option plans. The Compensation
Committee  makes  recommendations  to  the  Board as  to  the  salaries  of, and
incentive bonuses awarded to,  the Company's CEO  and other executive  officers.
The  Stock Option Plan Administration Committee  determines the number and terms
of options granted to the Company's CEO, other executive officers and all  other
employees.

    Executive  compensation  consists of  three  major components:  base salary,
annual incentive bonus  and stock options.  Base salaries of  the CEO and  other
executive  officers  are subjectively  determined,  based on  annual  surveys of
similar positions  at  other biotechnology  companies  (described below  as  the
Comparison  Group), together with assessments  of individual performance and the
Company's achievement  of predetermined  operating  goals that  are  established
annually  by the Board (the goals established for 1994 are described below). The
Compensation Committee does not assign relative weights to the factors on  which
base   salaries  are  based.  Assessments   of  individual  performance  include
subjective evaluations of the value of individual executives to the Company. The
surveys employed include  some, but not  all, of the  companies included in  the
Nasdaq  Pharmaceutical Index, which is one of  the indices used in the Company's
performance graph that appears  elsewhere in this  Proxy Statement. During  1993
and  1994,  the compensation  survey data  used by  the Company  for comparative
purposes is  reported  as of  June  of  each year.  The  Company's  Compensation
Committee  meets  in  December  of  each year  to  determine  the  annual salary
component of executive compensation to be  paid in the following calendar  year,
and  the amount of  incentive bonus compensation,  in the form  of both cash and
stock options, to  be awarded executives  for performance in  the current  year.
Thus,  the 1994  salaries paid executives  were determined by  reference to 1993
compensation survey data, adjusted upwards for inflation during the term between
June 1993 and  December 1993.  The survey  data considered  by the  Compensation
Committee in determining executive salaries included salary information provided
by  36  biotechnology  companies  having  more  than  300  employees  (the "1993
Comparison Group"),  as well  as  a subgroup  of  the 10  largest  biotechnology
companies  (the "1993 Comparison Subgroup"). The Compensation Committee believes
that each of  the 1993 Comparison  Group and the  1993 Comparison Subgroup  were
representative   of  industry  norms  in  late   1993,  and  each  are  weighted
approximately  equally  by  the  Compensation  Committee.  The  1993  Comparison
Subgroup  consisted  of  Amgen,  Inc.,  Biogen,  Inc.,  Genentech,  Inc., Chiron
Corporation, Collagen  Corporation,  Genetics  Institute,  Genzyme  Corporation,
Repligen  Corporation  and  Synergen  Corporation.  In  June  1994,  the Company
obtained an updated  compensation survey  reflecting 1994 salaries  paid in  the
industry.  The 1994 Compensation  Group consisted of  47 biotechnology companies
having more than 300 employees, and the 1994 Compensation Subgroup consisted  of
each  of the companies in the 1993  Compensation Subgroup, but added Scios Nova,
Inc. and biotechnology affiliates or  subsidiaries of Baxter Healthcare,  Berlex
Biosciences,  Boehringer  Mannheim,  Bristol-Myers  Squibb  Company, Hoffmann-La
Roche, Inc.,  American  Cyanamid Company  (Lederle  Praxis), Miles,  Inc.,  Novo
Nordisk  and Syntex Corporation,  and deleted Collagen  Corporation and Repligen
Corporation. The comparisons  noted below  take into  account 1994  compensation
survey  information.  In the  case of  Mr.  Fritzky, the  Compensation Committee
established a base salary for 1994 of $325,000, which represented  approximately
91%  of the average 1994 compensation for  CEOs in the 1994 Comparison Group and
69% of the average  1994 compensation for CEOs  in the Comparison Subgroup.  The
Compensation  Committee established 1994  base salaries for  the Company's other
executive officers

                                       23
<PAGE>
ranging from  100% to  132%  of the  average  1994 compensation  for  executives
performing similar functions in companies included in the 1994 Comparison Group,
and  from 84% to 117% of the average 1994 compensation for executives performing
similar functions in companies included in the Comparison Subgroup.

    Under  the  Company's  compensation  plans,  annual  incentive  bonuses  are
calculated  as a percentage of base salary  and are based in part on achievement
of corporate  operating goals  and in  part on  individual contributions  toward
achieving such goals. The CEO and each of the other named executive officers are
eligible  for a team bonus of up to 25% of base salary, based on the achievement
of corporate operating goals, and an additional individual bonus of up to  12.5%
of base salary based on individual contributions toward achievement of corporate
operating  goals and subjective evaluation of individual performance. Individual
bonuses in excess of 12.5% of base salary have been awarded under  circumstances
determined by the Compensation Committee to merit special recognition. Corporate
operating  goals are established at  the beginning of each  year and approved by
the Board. Achievement  of corporate operating  goals provides the  Compensation
Committee and the Board with a basis for the award of incentive bonuses.

    For  1994, the Compensation  Committee elected to award  Mr. Fritzky and the
other named executive officers a team bonus of 65% of the amount for which  each
officer  was  eligible  (i.e., 65%  of  25%  of base  salary).  The Compensation
Committee's decision took into account that the Company had achieved 10 of 12 of
its established 1994 corporate operating goals within the time frames prescribed
by the Board. These goals (which were not assigned relative weights and are  not
listed  in order of relative importance)  were: (i) achievement of 1994 budgeted
net product  sales; (ii)  submission of  a product  license application  ("PLA")
amendment   for  use   of  Leukine-Registered   Trademark-  in   treating  acute
nonlymphocytic leukemia  and  completion  of  all  responses  to  FDA  questions
concerning   a  pending   PLA  amendment   for  use   of  Leukine   in  treating
chemotherapy-induced neutropenia  by  established  dates;  (iii)  attainment  of
patient-accrual targets for PIXY321 pivotal clinical trials; (iv) achievement of
specified  PIXY321 manufacturing and validation  objectives; (v) commencement of
specified  clinical   studies   for   Novantrone-Registered   Trademark-;   (vi)
development  of  a five-year  strategic  plan for  the  Company as  a  whole and
formation of a  strategic planning  committee for  Company information  systems;
(vii)  consolidation  of distribution,  customer service  and credit/collections
functions into a single operation; (viii) completion of staffing of the  medical
development  function; (ix) use of a multifunctional review system to prioritize
pre- development projects  and the identification  of at least  two new  product
candidates  from such pre-development projects; (x)  assessment of the impact of
healthcare reform  initiatives upon  Company  business and  product  development
strategies; (xi) preparation and filing of an IND for IL-4 receptor by a defined
date;  and (xii)  achievement of a  specified net loss  target. The Compensation
Committee's determination of  the team  bonus and individual  bonuses took  into
account that the Company had not achieved its 1994 budgeted net product sales or
the net loss target established by the beginning of 1994. However, in awarding a
team  bonus of 65%, the Compensation Committee took into account that management
has taken  action in  the  third and  fourth  quarters to  significantly  reduce
operating  expenses and  that all other  operating goals  had substantially been
achieved.  Although  attainment   of  the  goal   concerning  consolidation   of
distribution  functions  was  deferred  due to  the  reorganization  of Cyanamid
subsequent to  its  acquisition  by American  Home  Products,  the  Compensation
Committee  took into account  that the Company  had completed a  plan to achieve
this goal that would be implemented in the first half of 1995.

    The Compensation Committee also elected to  award Mr. Fritzky and the  other
named  executive officers  individual bonuses ranging  from 6% to  12.5% of base
salary, based upon  the Compensation Committee's  subjective assessment of  each
officer's   achievements  in  1994.  In   determining  individual  bonuses,  the
Compensation Committee considered  each individual  executive's contribution  to
the Company's operating goals. Mr. Fritzky received an individual bonus equal to
8.1% of his 1994 base salary.

    To  qualify compensation for deductibility  for federal income tax purposes,
it is the Company's policy to meet the requirements for exclusion from the limit
on deduction imposed by Section 162(m)

                                       24
<PAGE>
of the  Code by  paying  performance-based compensation  if possible  and,  with
respect  to  cases in  which it  is not  possible to  meet the  requirements for
exclusion from Section 162(m) of the  Code, the Company intends to minimize  any
award of compensation in excess of the limit.

    Stock  options have  been granted  periodically to  the CEO  and other named
executive officers to encourage management  of the Company from the  perspective
of  an owner with an equity interest  in the business. Stock options are awarded
by the Stock  Option Plan Administration  Committee, which is  comprised of  the
nonmanagement  directors of the Company. Options to purchase 125,000 shares were
granted to Mr.  Fritzky in  1994. No  options were  granted to  any other  named
executive  officers in 1994.  The number of  options awarded to  Mr. Fritzky was
determined based upon the Compensation Committee's subjective assessment of  the
level  of  stock option  compensation  that would  be  appropriate to  provide a
long-term incentive to Mr.  Fritzky linked to  an increase in  the value of  the
Company's common stock.

    COMPENSATION COMMITTEE
        Kirby J. Cramer
        John E. Lyons
        Edith W. Martin

    STOCK OPTION PLAN ADMINISTRATION COMMITTEE
        Frank V. AtLee (retired)
        David R. Bethune (retired)
        Kirby L. Cramer
        John E. Lyons
        Edith W. Martin

                                       25
<PAGE>
                               PERFORMANCE GRAPH
                 COMPARISON OF FIVE-YEAR CUMULATIVE RETURN (1)
   AMONG THE COMPANY, NASDAQ COMPOSITE INDEX AND NASDAQ PHARMACEUTICAL INDEX

EDGAR REPRESENTATION OF DATA POINTS USED IN PRINTED GRAPHIC

<TABLE>
<CAPTION>
            NASDAQ COMPOSITE   NASDAQ PHARMACEUTICAL    COMPANY
<S>        <C>                 <C>                     <C>
12/31/89                  100                     100        100
12/31/90                84.92                  119.95     185.71
12/31/91               136.28                  318.78     307.79
12/31/92               158.58                  265.53     266.23
12/31/93               180.93                  236.63     151.76
12/31/94               176.92                   178.4     138.91
</TABLE>

------------------------

(1)  Assumes $100 invested at  the close of trading on  December 31, 1989 in the
    Common Stock, in the Nasdaq Composite Index and in the Nasdaq Pharmaceutical
    Index.

NOTE: Stock price performance shown above for the Common Stock is historical and
      not necessarily indicative of future price performance.

SECTION 16 REPORTING

    Section 16(a)  of  the Exchange  Act  requires the  Company's  officers  and
directors,  and  persons who  own more  than 10%  of a  registered class  of the
Company's equity  securities,  to  file  reports of  ownership  and  changes  in
ownership  with  the  Commission.  Officers,  directors  and  greater  than  10%
shareholders are required by Commission  regulation to furnish the Company  with
copies of all Section 16(a) forms they file.

    Based  solely on its review  of the copies of such  forms received by it, or
written representations  from  certain  reporting persons  that  no  forms  were
required  for those  persons, the Company  believes that during  1994 all filing
requirements  applicable  to  its  officers,  directors  and  greater  than  10%
beneficial owners were complied with by such persons.

                RELATIONSHIP WITH INDEPENDENT PUBLIC ACCOUNTANTS

    The  Board of  Directors has  selected Ernst  & Young  LLP, certified public
accountants, to act as  independent auditor of the  Company for the fiscal  year
ending  December 31,  1995. Ernst &  Young LLP  has been auditor  of the Company
since the Company's inception.

                                       26
<PAGE>
    A representative of  Ernst &  Young LLP  is expected  to be  present at  the
Annual  Meeting, with the opportunity to make a statement, if the representative
so desires, and is expected to be available to respond to appropriate  questions
from shareholders.

               DEADLINE FOR RECEIPT OF SHAREHOLDER PROPOSALS FOR
                              1995 ANNUAL MEETING

    Under  the Commission's proxy rules, shareholder proposals that meet certain
conditions may be  included in  the Company's proxy  statement and  proxy for  a
particular  annual meeting.  Proposals of shareholders  that are  intended to be
presented by such  shareholders at  the Company's  1995 Annual  Meeting must  be
received  by the Company  no later than  November 28, 1995  to be considered for
inclusion in the  proxy statement and  form of proxy  relating to that  meeting.
Receipt  by the Company of  any such proposal from  a qualified shareholder in a
timely manner will  not ensure  its inclusion  in the  Company's proxy  material
because there are other requirements in the proxy rules for such inclusion.

                                 OTHER MATTERS

    As  of the  date of this  Proxy Statement,  the Board of  Directors does not
intend to present, and has  not been informed that  any other person intends  to
present,  any matters for  action at the  Annual Meeting other  than the matters
specifically referred to in this Proxy Statement. If other matters properly come
before the Annual Meeting, it is intended  that the holders of the Proxies  will
act in respect thereto in accordance with their best judgment.

    Copies  of  the  1994 Annual  Report  of  the Company  are  being  mailed to
shareholders, together with this  Proxy Statement, form of  Proxy and Notice  of
Annual  Meeting  of Shareholders.  Additional copies  may  be obtained  from the
Secretary of the Company, 51 University Street, Seattle, Washington 98101.

    THE COMPANY'S ANNUAL REPORT ON FORM 10-K FOR THE FISCAL YEAR ENDED  DECEMBER
31,  1994, AS FILED WITH THE SECURITIES  AND EXCHANGE COMMISSION, IS INCLUDED IN
THE COMPANY'S 1994 ANNUAL REPORT TO SHAREHOLDERS.

                                          BY ORDER OF THE BOARD OF DIRECTORS

                                          Scott G. Hallquist
                                          SECRETARY
Seattle, Washington
March 24, 1995

                                       27
<PAGE>

                                                                /X/  PLEASE MARK
                                                                     YOUR CHOICE
                                                                       LIKE THIS
                                    --------
                                     Common

SHARES REPRESENTED BY THIS PROXY WILL BE VOTED AS DIRECTED BY THE SHAREHOLDER IN
THE SPACES PROVIDED.  IF NO DIRECTION IS GIVEN, THIS PROXY WILL BE VOTED "FOR
                   ALL NOMINEES" IN ITEM 1 AND "FOR" ITEM 2.

--------------------------------------------------------------------------------
The Board of Directors recommends a vote "FOR all Nominees" in Item 1 and "FOR"
Item 2.
--------------------------------------------------------------------------------
                                                       WITHHOLD
                                                       AUTHORITY
                                        FOR all       to vote for
                                        Nominees      all nominees

Item 1.   Election of the eight            / /             / /
          nominees to serve as
          directors for the ensuing
          year and until their
          successors are elected
          and qualify:

Joeseph J. Carr, Kirby L. Cramer, Robert A. Essner,
Edward V. Fritzky, Steven Gillis, Michael L. Kranda,
John E. Lyons and Edith W. Martin

WITHHOLD for the following only: (Write the name of the nominee(s) in the
space below)

__________________________________________

Unless otherwise directed, all votes will be apportioned equally among those
persons for whom authority is given to vote.

                                         FOR       AGAINST        ABSTAIN
Item 2.   Approve the increase in the    / /         / /            / /
          number of shares issuable
          under the Amended 1993 Stock
          Option Plan.

                                I plan to attend the Annual Meeting / /

Please sign exactly as your name appears hereon.
Attorneys, trustees, executors and other fiduciaries
acting in a representative capacity should sign their
names and give their titles.  An authorized person
should sign on behalf of corporations, partnerships,
associations, etc. and give his or her title.  If your
shares are held by two or more persons, each person must
sign.  Receipt of the notice of meeting and proxy statement
is hereby acknowledged.

COMMENTS/ADDRESS CHANGE                 / /

PLEASE MARK THIS BOX IF YOU HAVE
WRITTEN COMMENTS/ADDRESS CHANGE
ON THE REVERSE SIDE

Signature(s)_____________________________________     Date _____________________

Note: Please sign as name appears hereon. Joint owners should each sign. When
signing as attorney, executor, administrator, trustee or guardian, please give
full title as such.

-------------------------------------------------------------------------------
                              FOLD AND DETACH HERE
<PAGE>

                               IMMUNEX CORPORATION
            THIS PROXY IS SOLICITED BY THE BOARD OF DIRECTORS FOR THE
                 ANNUAL MEETING OF SHAREHOLDERS--APRIL 26, 1995

          The undersigned hereby appoint(s) Edward V. Fritzky and Michael L.
   P      Kranda and each of them as proxies, with full power of substitution,
          to represent and vote as designated all shares of Common Stock of
   R      Immunex Corporation held of record by the undersigned on March 14,
          1995 at the Annual Meeting of Shareholders of the Company to be held
   O      at the Four Seasons Olympic Hotel, 411 University Street, Seattle,
          Washington, at 9:00 a.m. on Wednesday, April 26, 1995, with authority
   X      to vote upon the following matters and with discretionary authority as
          to any other matters that may properly come before the meeting or any
   Y      adjournment or postponement thereof.

               IMPORTANT--PLEASE DATE AND SIGN ON THE OTHER SIDE.




                                                                ----------------
                                                                See Reverse Side
                                                                ----------------

--------------------------------------------------------------------------------
                              FOLD AND DETACH HERE

<PAGE>

                                                                   APPENDIX A

                               IMMUNEX CORPORATION

                   AMENDED AND RESTATED 1993 STOCK OPTION PLAN

SECTION 1.  PURPOSE

     The purpose of the Amended and Restated 1993 Stock Option Plan (this
"Plan") is to provide a means whereby selected employees, directors and officers
of Immunex Corporation (the "Company"), or of any parent or subsidiary (as
defined in subsection 5.8 and referred to hereinafter as "related corporations")
thereof, may be granted incentive stock options and/or nonqualified stock
options to purchase the Common Stock (as defined in Section 3) of the Company,
in order to attract and retain the services or advice of such employees,
directors and officers and to provide added incentive to such persons by
encouraging stock ownership in the Company.

SECTION 2.  ADMINISTRATION

     This Plan shall be administered by a Stock Option Plan Administration
Committee (the "Committee") appointed by the Board of Directors of the Company
(the "Board").  The Committee shall be composed of two or more members of the
Board who are "disinterested persons" as defined in Rule 16b-3(d) of the
Securities Exchange Act of 1934, as amended from time to time (the "Exchange
Act").  The administrator of this Plan shall hereinafter be referred to as the
"Plan Administrator."

     2.1  PROCEDURES

     The Board shall designate one of the members of the Plan Administrator as
chairman.  The Plan Administrator may hold meetings at such times and places as
it shall determine.  The acts of a majority of the members of the Plan
Administrator present at meetings at which a quorum exists, or acts reduced to
or approved in writing by all Plan Administrator members, shall be valid acts of
the Plan Administrator.

     2.2  RESPONSIBILITIES

     Except for the terms and conditions explicitly set forth in this Plan, the
Plan Administrator shall have the authority, in its discretion, to determine all
matters relating to the options to be granted under this Plan, including
selection of the individuals to be granted options, the number of shares to be
subject to each option, the exercise price, and all other terms and conditions
of the options.  Grants under this Plan need not be identical in any respect,
even when made simultaneously.  The interpretation and construction by the


                                       -1-
<PAGE>

Plan Administrator of any terms or provisions of this Plan or any option issued
hereunder, or of any rule or regulation promulgated in connection herewith,
shall be conclusive and binding on all interested parties, so long as such
interpretation and construction with respect to incentive stock options
correspond to the requirements of Section 422 of the Internal Revenue Code of
1986, as amended (the "Code"), the regulations thereunder and any amendments
thereto.

     2.3  SECTION 16(b) COMPLIANCE AND BIFURCATION OF PLAN

     It is the intention of the Company that, if any of the Company's equity
securities are registered pursuant to Section 12(b) or 12(g) of the Exchange
Act, this Plan shall comply in all respects with Rule 16b-3 under the Exchange
Act and, if any Plan provision is later found not to be in compliance with such
Section, the provision shall be deemed null and void, and in all events this
Plan shall be construed in favor of its meeting the requirements of Rule 16b-3.
Notwithstanding anything in this Plan to the contrary, the Board, in its
absolute discretion, may bifurcate this Plan so as to restrict, limit or
condition the use of any provision of this Plan to participants who are officers
and directors subject to Section 16 of the Exchange Act without so restricting,
limiting or conditioning this Plan with respect to other participants.

SECTION 3.  STOCK SUBJECT TO THIS PLAN

     The stock subject to this Plan shall be the Company's Common Stock, par
value $.01 per share (the "Common Stock"), presently authorized but unissued
or now held or subsequently acquired by the Company as treasury shares. Subject
to adjustment as provided in Section 7, the aggregate amount of Common Stock to
be delivered upon the exercise of all options granted under this Plan shall not
exceed 6,225,267 shares.  If any option granted under this Plan shall expire or
be surrendered, exchanged for another option, cancelled or terminated for any
reason without having been exercised in full, the unpurchased shares subject
thereto shall thereupon again be available for purposes of this Plan, including
for replacement options which may be granted in exchange for such expired,
surrendered, exchanged, cancelled or terminated options.

SECTION 4.  ELIGIBILITY

     An incentive stock option may be granted only to any individual who, at the
time the option is granted, is an employee of the Company or any related
corporation.  A nonqualified stock option may be granted to any employee,


                                       -2-
<PAGE>

director or officer of the Company or any related corporation, whether an
individual or an entity.  Any party to whom an option is granted under this Plan
shall be referred to hereinafter as an "Optionee."

SECTION 5.  TERMS AND CONDITIONS OF OPTIONS

     Options granted under this Plan shall be evidenced by written agreements
which shall contain such terms, conditions, limitations and restrictions as the
Plan Administrator shall deem advisable and which are not inconsistent with this
Plan. Notwithstanding the foregoing, options shall include or incorporate by
reference the following terms and conditions:

     5.1  NUMBER OF SHARES AND PRICE

     The maximum number of shares that may be purchased pursuant to the exercise
of each option and the price per share at which such option is exercisable (the
"exercise price") shall be as established by the Plan Administrator, provided
that the Plan Administrator shall act in good faith to establish the exercise
price which shall be not less than the fair market value per share of the Common
Stock at the time the option is granted with respect to incentive stock options
and not less than the par value per share of the Common Stock at the time the
option is granted with respect to nonqualified stock options and also provided
that, with respect to incentive stock options granted to greater than 10%
stockholders, the exercise price shall be as required by subsection 6.1.

     5.2  TERM AND MATURITY

     Subject to the restrictions contained in Section 6 with respect to granting
incentive stock options to greater than 10% stockholders, the term of each
incentive stock option shall be as established by the Plan Administrator and, if
not so established, shall be 10 years from the date it is granted but in no
event shall it exceed 10 years.  The term of each nonqualified stock option
shall be as established by the Plan Administrator and, if not so established,
shall be 10 years. To ensure that the Company or related corporation will
achieve the purpose and receive the benefits contemplated in this Plan, any
option granted to any Optionee hereunder shall, unless the condition of this
sentence is waived or modified in the agreement evidencing the option or by
resolution adopted at any time by the Plan Administrator, be exercisable
according to the following schedule:


                                       -3-
<PAGE>

Period of Optionee's
Continuous Relationship
With the Company or Related
Corporation From the Date           Portion of Total Option
the Option Is Granted               Which Is Exercisable
---------------------------------------------------------------

      after one year                         20%

     after two years                         40%

   after three years                         60%

    after four years                         80%

    after five years                        100%


          5.3  EXERCISE

     Subject to the vesting schedule described in subsection 5.2, each option
may be exercised in whole or in part at any time and from time to time;
provided, however, that no fewer than 20% of the shares purchasable under the
option (or the remaining shares then purchasable under the option, if less than
20%) may be purchased upon any exercise of option rights hereunder and that only
whole shares will be issued pursuant to the exercise of any option and that the
exercise price shall not be less than the par value per share of the Common
Stock at the time the option is exercised. During an Optionee's lifetime, any
options granted under this Plan are personal to him or her and are exercisable
solely by such Optionee.  Options shall be exercised by delivery to the Company
of notice of the number of shares with respect to which the option is exercised,
together with payment of the exercise price.

     5.4  PAYMENT OF EXERCISE PRICE

     Payment of the option exercise price shall be made in full at the time the
notice of exercise of the option is delivered to the Company and shall be in
cash, bank certified or cashier's check or personal check (unless at the time of
exercise the Plan Administrator in a particular case determines not to accept a
personal check) for the Common Stock being purchased.

     The Plan Administrator can determine at any time before exercise that
additional forms of payment will be permitted. To the extent permitted by the
Plan Administrator and applicable laws and regulations (including, but not
limited to, federal tax and securities laws and regulations and state corporate
law), an option may be exercised by:


                                       -4-
<PAGE>

          (a)  delivery of shares of stock of the Company held by an Optionee
having a fair market value equal to the exercise price, such fair market value
to be determined in good faith by the Plan Administrator; provided, however,
that payment in stock held by an Optionee shall not be made unless the stock
shall have been owned by the Optionee for a period of at least six months;

          (b)  delivery of a full-recourse promissory note executed by the
Optionee in an amount which shall not exceed that portion of the exercise price
which is in excess of the amount determined to be stated capital pursuant to
Section 154 of the Delaware General Corporation Law; provided that (i) such note
delivered in connection with an incentive stock option shall, and such note
delivered in connection with a nonqualified stock option may, in the sole
discretion of the Plan Administrator, bear interest at a rate specified by the
Plan Administrator but in no case less than the rate required to avoid
imputation of interest (taking into account any exceptions to the imputed
interest rules) for federal income tax purposes, and (ii) the Plan Administrator
in its sole discretion shall specify the term and other provisions of such note
at the time an incentive stock option is granted or at any time prior to
exercise of a nonqualified stock option, and (iii) the Plan Administrator may
require that the Optionee pledge the Optionee's shares to the Company for the
purpose of securing the payment of such note and may require that the
certificate representing such shares be held in escrow in order to perfect the
Company's security interest, and (iv) the Plan Administrator in its sole
discretion may at any time restrict or rescind this right upon notification to
the Optionee;

          (c)  delivery of a properly executed exercise notice, together with
irrevocable instructions to a broker, all in accordance with the regulations of
the Federal Reserve Board, to promptly deliver to the Company the amount of sale
or loan proceeds to pay the exercise price and any federal, state or local
withholding tax obligations that may arise in connection with the exercise.

     5.5  WITHHOLDING TAX REQUIREMENT

     The Company or any related corporation shall have the right to retain and
withhold from any payment of cash or Common Stock under this Plan the amount of
taxes required by any government to be withheld or otherwise deducted and paid
with respect to such payment.  At its discretion, the Company may require an
Optionee receiving shares of Common Stock to reimburse the Company for any such
taxes required to be withheld by the Company and withhold any distribution in
whole or in part until the Company is so reimbursed.  In lieu


                                       -5-
<PAGE>

thereof, the Company shall have the right to withhold from any other cash
amounts due or to become due from the Company to the Optionee an amount equal to
such taxes.  The Company may also retain and withhold or the Optionee may elect,
subject to approval by the Company at its sole discretion, to have the Company
retain and withhold a number of shares having a market value not less than the
amount of such taxes required to be withheld by the Company to reimburse the
Company for any such taxes and cancel (in whole or in part) any such shares so
withheld.  In order to qualify such election for exemption under Rule 16b-3
promulgated under Section 16(b) of the Exchange Act, any election made by an
officer or director who is subject to Section 16 of the Exchange Act must be an
irrevocable election made six months prior to the date the option exercise
becomes taxable or such irrevocable election must become effective during the
quarterly 10-day window period required under Section 16(b) of the Exchange Act
for exercises of stock appreciation rights.

     5.6  HOLDING PERIODS

          5.6.1  SECURITIES EXCHANGE ACT SECTION 16

     No director or officer subject to Section 16(b) of the Exchange Act may
sell shares of Common Stock obtained upon the exercise of a stock option within
six months after the date the option was granted.

          5.6.2  TAXATION OF STOCK OPTIONS

     The Plan Administrator may require an Optionee to give the Company prompt
notice of any disposition of shares of Common Stock acquired by the exercise of
an incentive stock option prior to the expiration of two years after the date of
grant of the option and one year from the date of exercise.

     5.7  NONTRANSFERABILITY OF OPTIONS

     Options granted under this Plan and the rights and privileges conferred
hereby may not be transferred, assigned, pledged or hypothecated in any manner
(whether by operation of law or otherwise) other than by will or by the
applicable laws of descent and distribution and shall not be subject to
execution, attachment or similar process.  Any attempt to transfer, assign,
pledge, hypothecate or otherwise dispose of any option under this Plan or of any
right or privilege conferred hereby, contrary to the Code or to the provisions
of this Plan, or the sale or levy or any attachment or similar process upon the
rights and privileges conferred hereby shall be null and void.  Notwithstanding
the foregoing, if the Company permits, an Optionee may, during the Optionee's
lifetime, designate a person who may exercise the option after


                                       -6-
<PAGE>

the Optionee's death by giving written notice of such designation to the Plan
Administrator.  Such designation may be changed from time to time by the
Optionee by giving written notice to the Plan Administrator revoking any earlier
designation and making a new designation.

     5.8  TERMINATION OF RELATIONSHIP

     If the Optionee's relationship with the Company or any related corporation
ceases for any reason other than termination for cause, death or total
disability, and unless by its terms the option sooner terminates or expires,
then the Optionee may exercise, for a three-month period, that portion of the
Optionee's option which is exercisable at the time of such cessation, but the
Optionee's option shall terminate at the end of such period following such
cessation as to all shares for which it has not theretofore been exercised,
unless such provision is waived in the agreement evidencing the option.  If, in
the case of an incentive stock option, an Optionee's relationship with the
Company or any related corporation changes (I.E., from employee to nonemployee,
such as a consultant), such change shall constitute a termination of an
Optionee's employment with the Company or any related corporation and the
Optionee's incentive stock option shall terminate in accordance with this
subsection 5.8.  Upon the expiration of the three-month period following
cessation of employment in the case of an incentive stock option, or at any time
prior to the expiration of the option in the case of a nonqualified stock
option, the Plan Administrator shall have sole discretion in a particular
circumstance to extend the exercise period following such cessation to any date
up to the termination or expiration of the option.  If, however, in the case of
an incentive stock option, the Optionee does not exercise the Optionee's option
within three months after cessation of employment, the option will no longer
qualify as an incentive stock option under the Code.

     If an Optionee is terminated for cause, any option granted hereunder shall
automatically terminate as of the first discovery by the Company of any reason
for termination for cause, and such Optionee shall thereupon have no right to
purchase any shares pursuant to such option.  "Termination for cause" shall mean
dismissal for dishonesty, conviction or confession of a crime punishable by law
(except minor violations), fraud, misconduct or disclosure of confidential
information.

     If an Optionee's relationship with the Company or any related corporation
is suspended pending an investigation of whether or not the Optionee shall be
terminated for cause, all the Optionee's rights under any option granted
hereunder


                                       -7-
<PAGE>

likewise shall be suspended during the period of investigation.

     If an Optionee's relationship with the Company or any related corporation
ceases because of a total disability, the Optionee's option shall not terminate
or, in the case of an incentive stock option, cease to be treated as an
incentive stock option until the end of the 12-month period following such
cessation (unless by its terms it sooner terminates and expires).  As used in
this Plan, the term "total disability" refers to a mental or physical impairment
of the Optionee which is expected to result in death or which has lasted or is
expected to last for a continuous period of 12 months or more and which causes
the Optionee to be unable, in the opinion of the Company and two independent
physicians, to perform his or her duties for the Company and to be engaged in
any substantial gainful activity.  Total disability shall be deemed to have
occurred on the first day after the Company and the two independent physicians
have furnished their opinion of total disability to the Plan Administrator.

     Options granted under the Plan shall not be affected by any change of
relationship with the Company so long as the Optionee continues to be an
employee, director, officer, agent, consultant, advisor or independent
contractor of the Company or of a related corporation; however, a change in an
Optionee's status from an employee to a nonemployee (e.g., consultant or
independent contractor) shall result in the termination of an outstanding
incentive stock option held by such Optionee.  The Plan Administrator, in its
absolute discretion, may determine all questions of whether particular leaves of
absence constitute a termination of services; provided, however, that with
respect to incentive stock options, such determination shall be subject to any
requirements contained in the Code.  The foregoing notwithstanding, with respect
to incentive stock options, employment shall not be deemed to continue beyond
the first 90 days of such leave, unless the Optionee's reemployment rights are
guaranteed by statute or by contract.

     As used herein, the term "related corporation," when referring to a
subsidiary corporation, shall mean any corporation (other than the Company) in,
at the time of the granting of the option, an unbroken chain of corporations
ending with the Company, if stock possessing 50% or more of the total combined
voting power of all classes of stock of each of the corporations other than the
Company is owned by one of the other corporations in such chain.  When referring
to a parent corporation, the term "related corporation" shall mean any
corporation in an unbroken chain of corporations ending with the Company if, at
the time of the granting of the option, each of the corporations other than the
Company owns


                                       -8-
<PAGE>

stock possessing 50% or more of the total combined voting power of all classes
of stock in one of the other corporations in such chain.

     5.9  DEATH OF OPTIONEE

     If an Optionee dies while he or she has a relationship with the Company or
any related corporation or within the three-month period (or 12-month period in
the case of totally disabled Optionees) following cessation of such
relationship, any option held by such Optionee to the extent that the Optionee
would have been entitled to exercise such option, may be exercised within one
year after his or her death by the personal representative of his or her estate
or by the person or persons to whom the Optionee's rights under the option shall
pass by will or by the applicable laws of descent and distribution.

     5.10 NO STATUS AS STOCKHOLDER

     Neither the Optionee nor any party to which the Optionee's rights and
privileges under the option may pass shall be, or have any of the rights or
privileges of, a stockholder of the Company with respect to any of the shares
issuable upon the exercise of any option granted under this Plan unless and
until such option has been exercised.

     5.11 CONTINUATION OF RELATIONSHIP

     Nothing in this Plan or in any option granted pursuant to this Plan shall
confer upon any Optionee any right to continue in the employ or other
relationship of the Company or of a related corporation, or to interfere in any
way with the right of the Company or of any such related corporation to
terminate his or her employment or other relationship with the Company at any
time.

     5.12 MODIFICATION AND AMENDMENT OF OPTION

     Subject to the requirements of Code Section 422 with respect to incentive
stock options and to the terms and conditions and within the limitations of this
Plan, the Plan Administrator may modify or amend outstanding options granted
under this Plan.  The modification or amendment of an outstanding option shall
not, without the consent of the Optionee, impair or diminish any of his or her
rights or any of the obligations of the Company under such option.  Except as
otherwise provided in this Plan, no outstanding option shall be terminated
without the consent of the Optionee. Unless the Optionee agrees otherwise, any
changes or adjustments made to outstanding incentive stock options granted under
this Plan shall be made in such a manner so as


                                       -9-
<PAGE>

not to constitute a "modification" as defined in Code Section 424(h) and so as
not to cause any incentive stock option issued hereunder to fail to continue to
qualify as an incentive stock option as defined in Code Section 422(b).

     5.13 LIMITATION ON VALUE FOR INCENTIVE STOCK OPTIONS

     As to all incentive stock options granted under the terms of this Plan, to
the extent that the aggregate fair market value of the stock (determined at the
time the incentive stock option is granted) with respect to which incentive
stock options are exercisable for the first time by the Optionee during any
calendar year (under this Plan and all other incentive stock option plans of the
Company, a related corporation or a predecessor corporation) exceeds $100,000,
such options shall be treated as nonqualified stock options. The previous
sentence shall not apply if the Internal Revenue Service issues a public rule,
issues a private ruling to the Company, any Optionee or any legatee, personal
representative or distributee of an Optionee or issues regulations changing or
eliminating such annual limit.

SECTION 6.  GREATER THAN 10% STOCKHOLDERS

     6.1  EXERCISE PRICE AND TERM OF INCENTIVE STOCK OPTIONS

     If incentive stock options are granted under this Plan to employees who own
more than 10% of the total combined voting power of all classes of stock of the
Company or any related corporation, the term of such incentive stock options
shall not exceed five years and the exercise price shall be not less than 110%
of the fair market value of the Common Stock at the time the incentive stock
option is granted.  This provision shall control notwithstanding any contrary
terms contained in an option agreement or any other document.

     6.2  ATTRIBUTION RULE

     For purposes of subsection 6.1, in determining stock ownership, an employee
shall be deemed to own the stock owned, directly or indirectly, by or for his or
her brothers, sisters, spouse, ancestors and lineal descendants.  Stock owned,
directly or indirectly, by or for a corporation, partnership, estate or trust
shall be deemed to be owned proportionately by or for its stockholders, partners
or beneficiaries.  If an employee or a person related to the employee owns an
unexercised option or warrant to purchase stock of the Company, the stock
subject to that portion of the option or warrant which is unexercised shall not
be counted in determining stock ownership.  For purposes of this Section 6,
stock owned by an employee shall include all stock actually


                                      -10-
<PAGE>

issued and outstanding immediately before the grant of the incentive stock
option to the employee.

SECTION 7.  ADJUSTMENTS UPON CHANGES IN CAPITALIZATION

     The aggregate number and class of shares for which options may be granted
under this Plan, the number and class of shares covered by each outstanding
option and the exercise price per share thereof (but not the total price), and
each such option, shall all be proportionately adjusted for any increase or
decrease in the number of issued shares of Common Stock of the Company resulting
from a split-up or consolidation of shares or any like capital adjustment, or
the payment of any stock dividend.

     7.1  EFFECT OF LIQUIDATION OR REORGANIZATION

          7.1.1  CASH, STOCK OR OTHER PROPERTY FOR STOCK

     Except as provided in subsection 7.1.2, upon a merger (other than a merger
of the Company in which the holders of Common Stock immediately prior to the
merger have the same proportionate ownership of Common Stock in the surviving
corporation immediately after the merger), consolidation, acquisition of
property or stock, separation, reorganization (other than a mere reincorporation
or the creation of a holding company) or liquidation of the Company, as a result
of which the stockholders of the Company receive cash, stock or other property
in exchange for or in connection with their shares of Common Stock, any option
granted hereunder shall terminate, but the Optionee shall have the right
immediately prior to any such merger, consolidation, acquisition of property or
stock, separation, reorganization or liquidation to exercise such Optionee's
option in whole or in part whether or not the vesting requirements set forth in
the option agreement have been satisfied.

          7.1.2  CONVERSION OF OPTIONS ON STOCK FOR STOCK EXCHANGE

     If the stockholders of the Company receive capital stock of another
corporation ("Exchange Stock") in exchange for their shares of Common Stock in
any transaction involving a merger (other than a merger of the Company in which
the holders of Common Stock immediately prior to the merger have the same
proportionate ownership of Common Stock in the surviving corporation immediately
after the merger), consolidation, acquisition of property or stock, separation
or reorganization (other than a mere reincorporation or the creation of a
holding company), the Company and the corporation issuing the Exchange Stock, in
their sole discretion, may determine that all options granted hereunder


                                      -11-
<PAGE>

shall be converted into options to purchase shares of Exchange Stock instead of
terminating in accordance with the provisions of subsection 7.1.1.  The amount
and price of converted options shall be determined by adjusting the amount and
price of the options granted hereunder in the same proportion as used for
determining the number of shares of Exchange Stock the holders of the Common
Stock receive in such merger, consolidation, acquisition of property or stock,
separation or reorganization.  Unless accelerated by the Board, the vesting
schedule set forth in the option agreement shall continue to apply to the
options granted for the Exchange Stock.

     7.2  FRACTIONAL SHARES

     In the event of any adjustment in the number of shares covered by any
option, any fractional shares resulting from such adjustment shall be
disregarded and each such option shall cover only the number of full shares
resulting from such adjustment.

     7.3  DETERMINATION OF BOARD TO BE FINAL

     All Section 7 adjustments shall be made by the Plan Administrator, and its
determination as to what adjustments shall be made, and the extent thereof,
shall be final, binding and conclusive.  Unless an Optionee agrees otherwise,
any change or adjustment to an incentive stock option shall be made in such a
manner so as not to constitute a "modification" as defined in Code Section
424(h) and so as not to cause his or her incentive stock option issued hereunder
to fail to continue to qualify as an incentive stock option as defined in Code
Section 422(b).

SECTION 8.  SECURITIES REGULATION

     Shares shall not be issued with respect to an option granted under this
Plan unless the exercise of such option and the issuance and delivery of such
shares pursuant thereto shall comply with all relevant provisions of law,
including, without limitation, any applicable state securities laws, the
Securities Act of 1933, as amended, the Exchange Act, the rules and regulations
promulgated thereunder, and the requirements of any stock exchange upon which
the shares may then be listed, and shall be further subject to the approval of
counsel for the Company with respect to such compliance, including the
availability of an exemption from registration for the issuance and sale of any
shares hereunder. Inability of the Company to obtain from any regulatory body
having jurisdiction, the authority deemed by the Company's counsel to be
necessary for the lawful issuance and sale of any shares hereunder or the
unavailability of an exemption from registration for the issuance and sale of
any shares hereunder


                                      -12-
<PAGE>

shall relieve the Company of any liability in respect of the nonissuance or sale
of such shares as to which such requisite authority shall not have been
obtained.

     As a condition to the exercise of an option, the Company may require the
Optionee to represent and warrant at the time of any such exercise that the
shares are being purchased only for investment and without any present intention
to sell or distribute such shares if, in the opinion of counsel for the Company,
such a representation is required by any relevant provision of the
aforementioned laws.  At the option of the Company, a stop-transfer order
against any shares of stock may be placed on the official stock books and
records of the Company, and a legend indicating that the stock may not be
pledged, sold or otherwise transferred unless an opinion of counsel is provided
(concurred in by counsel for the Company) stating that such transfer is not in
violation of any applicable law or regulation, may be stamped on stock
certificates in order to assure exemption from registration. The Plan
Administrator may also require such other action or agreement by the Optionees
as may from time to time be necessary to comply with the federal and state
securities laws.  THIS PROVISION SHALL NOT OBLIGATE THE COMPANY TO UNDERTAKE
REGISTRATION OF THE OPTIONS OR STOCK HEREUNDER.

     Should any of the Company's capital stock of the same class as the stock
subject to options granted hereunder be listed on a national securities
exchange, all stock issued hereunder if not previously listed on such exchange
shall be authorized by that exchange for listing thereon prior to the issuance
thereof.

SECTION 9.  AMENDMENT AND TERMINATION

     9.1  BOARD ACTION

     The Board may at any time suspend, amend or terminate this Plan, provided
that except as set forth in Section 7, and to the extent required by any
applicable law or requirement, the approval of a majority of stock represented
by stockholders voting either in person or by proxy at a duly held stockholders'
meeting is necessary within 12 months before or after the adoption by the Board
of any amendment which will:

          (a)  increase the number of shares that may be issued under this Plan;

          (b)  with respect to nonqualified stock options, materially modify the
requirements as to eligibility for participation in this Plan or, with respect
to incentive stock


                                      -13-
<PAGE>

options, change the designation of the participants or class of participants
eligible for participation in this Plan;

          (c)  materially increase the benefits accruing to the participants
under this Plan; or

          (d)  otherwise require stockholder approval under any applicable law
or regulation including but not limited to Section 16(b) of the Exchange Act.

     Any amendment made to this Plan which would constitute a "modification" to
incentive stock options outstanding on the date of such amendment, shall not be
applicable to such outstanding incentive stock options, but shall have
prospective effect only, unless the Optionee agrees otherwise.

     9.2  AUTOMATIC TERMINATION

     Unless sooner terminated by the Board, this Plan shall terminate ten years
from the earlier of (a) the date on which this Plan is adopted by the Board or
(b) the date on which this Plan is approved by the stockholders of the Company.
No option may be granted after such termination or during any suspension of this
Plan.  The amendment or termination of this Plan shall not, without the consent
of the option holder, alter or impair any rights or obligations under any option
theretofore granted under this Plan.

SECTION 10.  EFFECTIVENESS OF THIS PLAN

     This Amended and Restated Plan shall become effective upon adoption by the
Board so long as it is approved by a majority of stock represented by
stockholders voting either in person or by proxy at a duly held stockholders'
meeting any time within 12 months before or after the adoption of this Amended
and Restated Plan.

Plan adopted by the Board of Directors on March 11, 1993 and approved by the
sole stockholder on March 11, 1993. Ratified by the Board of Directors on June
1, 1993. Amended on July 14, 1993. Amendment to increase number of shares
issuable adopted by the Board of Directors on February 2, 1995.


                                      -14-



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