MOLECULAR BIOSYSTEMS INC
10-Q, 1996-02-14
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                                    Form 10-Q

                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
                                   (Mark One)

           [X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

                For the quarterly period ended December 31, 1995

                                       OR

          [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

        For the transition period from............... to ...............

                         Commission file number 0-12648


                           MOLECULAR BIOSYSTEMS, INC.
             (Exact name of registrant as specified in its charter)


                               Delaware 36-3078632
              (State of Incorporation) (I.R.S. Identification No.)


                            10030 Barnes Canyon Road
                           San Diego, California 92121
                                 (619) 452-0681
               (Address, including zip code, and telephone number,
              including area code, of principal executive offices)


Indicate by check mark whether the registrant (1) has filed all reports required
   to be filed by Section 13 or 15 (d) of the Securities Exchange Act of 1934
 during the preceding 12 months (or for such shorter period that the registrant
  was required to file such reports), and (2) has been subject to such filing
                       requirements for the past 90 days.

                                    X Yes No

 The number of shares outstanding of the issuer's common stock, $.01 par value,
                 as of February 9, 1996 was 13,290,736 shares.
<PAGE>


                                         INDEX                              PAGE

PART I - FINANCIAL INFORMATION

        Item 1 - Financial Statements

        1. Consolidated Balance Sheets                                        3

           December 31, 1995
           March 31, 1995

        2. Consolidated Statements of Operations                              5

           Three Months Ended December 31, 1995 and 1994 
           Nine Months Ended December 31, 1995 and 1994

        3. Consolidated Statements of Cash Flows                              6

           Nine Months Ended December 31, 1995 and 1994

        4. Notes to Financial Statements                                      7

        Item 2 - Management's Discussion and Analysis of
        Financial Condition and Results of Operations                         8


PART II -OTHER INFORMATION

        Item 1 - Legal Proceedings                                           13

        Item 2 - Changes in Securities                                       13

        Item 3 - Defaults Upon Senior Securities                             13

        Item 4 - Submission of Matters to a Vote of Securities Holders       13

        Item 5 - Other Information                                           13

        Item 6 - Exhibits and Reports on Form 8-K                            13

           (a) Exhibits
           (b) Reports on Form 8-K

        Signatures                                                           14

<PAGE>
<TABLE>
<CAPTION>
                   MOLECULAR BIOSYSTEMS, INC. AND SUBSIDIARIES

                           CONSOLIDATED BALANCE SHEETS

                                     ASSETS

                             (Dollars in thousands)

                                                                           December 31,
                                                                              1995            March 31,
                                                                          (Unaudited)           1995
                                                                        -----------------  ----------------
<S>                                                                              <C>               <C>   
CURRENT ASSETS:
     Cash and cash equivalents                                                    $2,231            $3,882
     Marketable securities, available-for-sale                                    18,889            15,836
     Accounts and notes receivable                                                   376             5,180
     Inventories                                                                     697             1,394
     Accrued interest receivable                                                      59                51
     Prepaid expenses and other assets                                               464               391
                                                                        -----------------  ----------------
          Total current assets                                                    22,716            26,734
                                                                        -----------------  ----------------

PROPERTY AND EQUIPMENT, at cost:
     Building and improvements                                                    20,577            18,125
     Equipment, furniture and fixtures                                             5,378             5,216
     Construction in progress                                                        886             2,253
                                                                        -----------------  ----------------
                                                                                  26,841            25,594
     Less:  Accumulated depreciation and amortization                              6,773             5,947
                                                                        -----------------  ----------------

                                                                                  20,068            19,647
                                                                        -----------------  ----------------

OTHER ASSETS:
     Patents and license rights, net                                                 341             1,724
     Other assets, net                                                             2,603             2,534
                                                                        -----------------  ----------------
                                                                                   2,944             4,258
                                                                        -----------------  ----------------

                                                                                 $45,728           $50,639
                                                                        =================  ================








</TABLE>

                             See accompanying notes.
<PAGE>
<TABLE>
<CAPTION>

                   MOLECULAR BIOSYSTEMS, INC. AND SUBSIDIARIES

                           CONSOLIDATED BALANCE SHEETS

                      LIABILITIES AND SHAREHOLDERS' EQUITY

                             (Dollars in thousands)


                                                                           December 31,
                                                                              1995            March 31,
                                                                          (Unaudited)           1995
                                                                        -----------------  ----------------
<S>                                                                              <C>               <C>   
CURRENT LIABILITIES:
     Accounts payable and accrued liabilities                                     $3,238            $5,089
     Current portion of long-term debt                                               307               307
     Compensation accruals                                                           658               411
                                                                        -----------------  ----------------
          Total current liabilities                                                4,203             5,807
                                                                        -----------------  ----------------

LONG-TERM DEBT, net of current portion                                             8,183             8,408
                                                                        -----------------  ----------------

COMMITMENTS AND CONTINGENCIES (Note 2)

SHAREHOLDERS' EQUITY:
     Common stock, $.01 par value,
       20,000,000 shares authorized,
       13,290,736 and 11,999,561 shares
       issued and outstanding, respectively                                          133               120
     Additional paid-in capital                                                   91,432            78,422
     Retained deficit                                                            (57,769)          (41,472)
     Unrealized loss on available-for-sale securities                                 (6)             (118)
     Less notes receivable from sale of common stock                                (281)             (469)
     Less treasury stock, at cost                                                   (167)              (59)
                                                                        -----------------  ----------------

          Total shareholders' equity                                              33,342            36,424
                                                                        -----------------  ----------------

                                                                                 $45,728           $50,639
                                                                        =================  ================
                
</TABLE>


                            See accompanying notes.

<PAGE>
<TABLE>
<CAPTION>


                                             MOLECULAR BIOSYSTEMS, INC. AND SUBSIDIARIES

                                                CONSOLIDATED STATEMENTS OF OPERATIONS

                                         (Unaudited; in thousands, except per share amounts)


                                                            THREE MONTHS ENDED                NINE MONTHS ENDED
                                                               DECEMBER 31,                     DECEMBER 31,
                                                            1995             1994             1995            1994
                                                      --------------   --------------   --------------  --------------
<S>                                                   <C>              <C>              <C>             <C>          
REVENUES:
   Revenues under collaborative agreements            $       1,013    $       6,188    $       1,412   $      14,921
   Product revenues                                             232              720              506           1,267
   License fees                                                   -                -               25              40
                                                      --------------   --------------   --------------  --------------
                                                              1,245            6,908            1,943          16,228
                                                      --------------   --------------   --------------  --------------

RESEARCH AND DEVELOPMENT COSTS:
   Compensation                                               1,499            1,519            4,111           5,404
   Equipment and supplies                                       545            1,384            1,549           3,312
   Outside research, preclinical and clinical trials             75              345              564           1,512
   Legal, professional and consulting                           355              275            1,022           1,093
   Occupancy costs                                              359              237            1,128           1,011
   Other                                                        443              492            1,483           1,779
                                                      --------------   --------------   --------------  --------------
                                                              3,276            4,252            9,857          14,111

COST OF PRODUCTS SOLD                                           587              643            1,311             988

SELLING, GENERAL AND ADMINISTRATIVE
   EXPENSES                                                   1,066            1,338            4,178           4,628

LITIGATION AND OTHER                                          3,110            3,000            3,110           3,000
                                                      --------------   --------------   --------------  --------------
        Total operating costs and expenses                    8,039            9,233           18,456          22,727
                                                      --------------   --------------   --------------  --------------

   LOSS FROM OPERATIONS                                      (6,794)          (2,325)         (16,513)         (6,499)

INTEREST EXPENSE                                               (195)            (193)            (596)           (496)
INTEREST INCOME                                                 344              283              812             930
                                                      --------------   --------------   --------------  --------------

NET LOSS                                              $      (6,645)   $      (2,235)   $     (16,297)  $      (6,065)
                                                      ==============   ==============   ==============  ==============

NET LOSS PER COMMON SHARE                             $       (0.50)   $       (0.19)   $       (1.30)  $       (0.51)
                                                      ==============   ==============   ==============  ==============
WEIGHTED AVERAGE COMMON SHARES
   OUTSTANDING                                               13,291           12,000           12,535          11,999
                                                      ==============   ==============   ==============  ==============






</TABLE>


                                               See accompanying notes.
<PAGE>
<TABLE>
<CAPTION>


                                             MOLECULAR BIOSYSTEMS, INC. AND SUBSIDIARIES

                                                CONSOLIDATED STATEMENTS OF CASH FLOWS

                                        FOR THE NINE MONTHS ENDED DECEMBER 31, 1995 AND 1994

                                                      (Unaudited; in thousands)

                                                                                            1995            1994
                                                                                        --------------  -------------
<S>                                                                                          <C>             <C>     
CASH FLOWS FROM OPERATING ACTIVITIES:
    Net loss                                                                                 ($16,297)       ($6,065)
    Adjustments to reconcile net loss to net cash
      used in operating activities:
       Depreciation and amortization                                                            1,868          2,455
       Write-down of property to be sold                                                          667              -
       Loss on write-off of license fees related to discontinued products                       1,025              -
       Forgiveness of note receivable from sale of common stock                                    56              -
       Changes in operating assets and liabilities:
        Receivables                                                                             4,740        (10,216)
        Inventories                                                                               697             49
        Prepaid expenses and other assets                                                         (73)          (242)
        Accounts payable and accrued liabilities                                                 (351)         3,185
        Compensation accruals                                                                     247             50
                                                                                        --------------  -------------
              Cash used in operating activities                                                (7,421)       (10,784)
                                                                                        --------------  -------------

CASH FLOWS FROM INVESTING ACTIVITIES:
    Purchases of property and equipment                                                        (1,945)          (882)
    Additions to patents and license rights                                                       (45)          (500)
    Increase in other assets                                                                     (677)             -
    (Increase) decrease in marketable securities                                               (2,941)         6,502
                                                                                        --------------  -------------
              Cash provided by (used in) investing activities                                  (5,608)         5,120
                                                                                        --------------  -------------

CASH FLOWS FROM FINANCING ACTIVITIES:
    Net proceeds from issuance of common shares                                                11,603            183
    Long-term debt proceeds                                                                         -          5,000
    Principal payments on long-term debt                                                         (225)          (180)
                                                                                        --------------  -------------
              Cash provided by financing activities                                            11,378          5,003
                                                                                        --------------  -------------

DECREASE IN CASH AND CASH
    EQUIVALENTS                                                                                (1,651)          (661)

CASH AND CASH EQUIVALENTS, beginning of period                                                  3,882          1,557
                                                                                        --------------  -------------

CASH AND CASH EQUIVALENTS, end of period                                                       $2,231           $896
                                                                                        ==============  =============

SUPPLEMENTAL CASH FLOW DISCLOSURES:

    Interest income received                                                                     $804         $1,063
                                                                                        ==============  =============
    Interest paid                                                                                $592           $492
                                                                                        ==============  =============
</TABLE>

                                              See accompanying notes.

<PAGE>

NOTES TO FINANCIAL STATEMENTS
- -----------------------------

(1)      Basis of Presentation-
         ----------------------

         The  Notes  to the  Consolidated  Financial  Statements  of  Molecular
         Biosystems, Inc. (the "Company") were submitted with the Company's Form
         10-K  for  the  year  ended  March  31,  1995  and  should  be  read in
         conjunction with this Form 10-Q.

         These interim  Consolidated  Financial  Statements of the Company have
         not been audited by independent  public  accountants.  However,  in the
         opinion  of  the  Company,   all   adjustments   required  for  a  fair
         presentation  of the  financial  position of the Company as of December
         31, 1995,  and the results of its  operations  for the three- and nine-
         months ended  December 31, 1995 and 1994, and its cash flows for
         the  nine-month  periods  ended  December 31, 1995 and 1994,  have been
         made.  The  results of  operations  for these  interim  periods are not
         necessarily indicative of the operating results for the full year.

(2)      Contingencies-
         --------------

         In May 1993 the Company  entered into an exclusive  license  agreement
         with Bracco S.p.A.  of Milan,  Italy,  for the  distribution  rights in
         Europe and the former  Soviet Union to the Company's  proprietary  oral
         ultrasound agent for imaging the  gastrointestinal  tract. At that time
         Bracco  paid the  Company a license  fee of $2  million  and  undertook
         certain  developmental  obligations  in the  territory.  In March 1994,
         Bracco  notified the Company  that it desired to rescind the  agreement
         and  demanded  that the  Company  return the license  fee.  The Company
         denied that Bracco was  entitled  to rescind  the  agreement  or to the
         return of any portion of the license fee. In January 1995, Bracco filed
         a demand for arbitration claiming return of the $2 million license fee,
         in  addition to other  monetary  relief.  The Company  filed a response
         denying the material  allegations of Bracco's  demand.  On November 22,
         1995,  the  arbitrator  ruled in favor of MBI on two counts of Bracco's
         claim;  however,  he also awarded  Bracco $1.7  million plus  statutory
         interest on a legal theory not advanced by Bracco. MBI is appealing the
         award.  As a  result  of  the  arbitrator's  ruling,  the  Company  has
         recognized a charge to operations of  approximately  $2.4 million to
         reflect the amount of the award,  interest  accrued thereon and related
         attorneys'  fees.  Of  this  charge,  approximately  $1.4  million  was
         recorded  during the  quarter  ended  December  31,  1995.  Included in
         accounts  payable and  accrued  liabilities  at December  31, 1995 is a
         reserve of $2 million for the possible payment of this award.

(3)      Stock Settlement-
         -----------------

         In June  1994,  the  United  States  District  Court for the  Southern
         District of California  granted final approval to an agreement settling
         a class action complaint  against the Company,  certain of its officers
         and all of the members of its Board of Directors (Sherman v. Widder, et
         al., No. TS  92-1827-IEG  (M)) alleging  violations  of the  Securities
         Exchange  Act of  1934  and  California  securities  laws.  Part of the
         settlement  agreement provided for the Company to issue shares of MBI's
         common stock worth $1.5 million to  qualifying  class  members.  In May
         1995, the stock was transferred to the qualifying class members.
<PAGE>

(4)       Litigation and Other-
          ---------------------

         During the quarters  ended December 31, 1995 and December 31, 1994, the
         Company recorded the following charges:

<TABLE>

                                                              Three Months Ended      Nine Months Ended
                                                                 December 31,           December 31,
                                                                1995       1994        1995        1994
                                                             ---------- ----------  ---------- -----------
<S>                                                          <C>        <C>         <C>        <C>       
Arbitration award and related costs                          $   1,418  $       -   $   1,418  $        -
Write-off of license fees related to discontinued products       1,025                  1,025
Write-down of real estate to be sold                               667          -         667           -
Approval bonus paid by U.S. marketing partner                        -      3,000           -       3,000
                                                             ---------- ----------  ---------- -----------
    Total litigation and other                               $   3,110  $   3,000   $   3,110  $    3,000
                                                             ========== ==========  ========== ===========

</TABLE>

         The  arbitration  award and related  costs are discussed in note (2) on
         page 7.


         As a result  of the  Company's  decision  to  focus  its  research  and
         development  activities on its ultrasound  contrast agents, the Company
         wrote-off   approximately   $1  million  of  license  fees  related  to
         discontinued products which previously had been capitalized.


         Additionally, in November 1995, the Company entered into a contract for
         the sale of the two  buildings  and  underlying  land that the  Company
         purchased in December 1993. The sale of the buildings is expected to be
         completed in March 1996. As a result,  the Company has written-down the
         carrying  value of the  buildings  by  $667,000  to the net  amount  it
         expects to receive from this sale.


         Finally,  during the  quarter  ended  December  31,  1994,  the Company
         received a bonus from Mallinckrodt  Medical, its U.S. marketing partner
         of  approximately  $3 million related to the approval of ALBUNEX(R) for
         marketing in the United  States.  Under the terms of the  marketing and
         distribution agreement with Mallinckrodt,  this bonus was paid to MBI's
         employees. As a result, the Company accrued a liability for the payment
         of these bonuses in the quarter ended  December 31, 1994 of $3 million.
         The bonus was paid to employees in the quarter ended March 31, 1995.


<PAGE>



PART I - FINANCIAL INFORMATION


Item 2 - MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
         OF OPERATIONS

         The  following  management  discussion  and analysis  should be read in
conjunction with (1) the current  consolidated  financial statements and (2) the
Company's  consolidated  financial  statements and  management's  discussion and
analysis of financial  condition  and results of operations in its Annual Report
on Form 10-K for the year ended March 31, 1995.

Liquidity and Capital Resources

         On September 7, 1995, the Company  entered into an amended and restated
distribution  agreement and a related  investment  agreement  with  Mallinckrodt
Medical, Inc.  ("Mallinckrodt")  which will provide the Company with between $33
million and $47.5  million in new  financing  (includes  the $13 million  common
stock  investment   discussed   below).   Under  the  terms  of  the  agreement,
Mallinckrodt  will pay the  Company  $20  million  over  four  years to  support
clinical  trials of FS069 (the  Company's  second-generation  cardiac  perfusion
product),  related regulatory  submissions and associated  product  development.
These payments will be made in 16 quarterly  installments starting at $1 million
for the first four quarters,  $1.25 million for the following eight quarters and
$1.5  million  for the final  four  quarters.  The first  and  second  quarterly
payments were paid on October 1, 1995 and January 2, 1996.

         The amended  distribution  agreement  requires  the Company to spend at
least $10 million of this $20 million on clinical  trials to support  regulatory
filings  with the FDA for cardiac  indications  of FS069.  After the Company has
spent this $10 million, the amended distribution  agreement requires the Company
and Mallinckrodt to share equally in the cost of any additional  clinical trials
of FS069 in the United States, up to a maximum total of $5 million ($2.5 million
each).

         The amended distribution agreement also provides for potential payments
to the Company of up to $12 million upon the satisfaction of certain milestones.
(There can be no assurance, however, that all or any of these milestones will be
satisfied.)

         In connection with the amended distribution agreement, the Company also
entered  into  an  investment  agreement  whereby  the  Company  sold  1,118,761
unregistered  shares of its common stock to Mallinckrodt  for $13 million,  or a
price of $11.62 per share before related  costs.  With the 181,818 shares of the
Company's  common stock that  Mallinckrodt  acquired in December  1988 (under an
investment agreement which the Company and Mallinckrodt entered into at the same
time as they  entered into the original  distribution  agreement),  Mallinckrodt
owns approximately 9.8% of the Company's issued and outstanding shares.

          The  Company  expects  that the  funding  provided  under the  amended
distribution  agreement to be its major  source of funds for Company  operations
over the next several  years.  At December 31, 1995, the Company had net working
capital of $18.5 million  compared to $20.9 million at March 31, 1995.  Cash and
current  marketable  securities were $21.1 million at December 31, 1995 compared
to $19.7 million at March 31, 1995.

         For the next several years,  the Company  expects to incur  substantial
additional expenditures associated with product development. As discussed above,
funding  provided  under the amended  distribution  agreement  will be the major
source to fund the Company's operating costs and expenses. The Company will also
continue to utilize  product  revenues from sales of ALBUNEX(R) and its existing
cash and  marketable  securities  and the  interest  earned  thereon to fund its
operations  and  capital  spending  needs.  The  Company  may pursue a number of
options to raise additional funds,  including  borrowings;  lease  arrangements;
collaborative   research  and  development   arrangements  with   pharmaceutical
companies;  the  licensing of product  rights to third  parties;  or  additional
public and private financing,  as anticipated  capital  requirements change as a
result of strategic,  competitive,  technological and regulatory factors.  There
can be no assurance that funds from these sources will be available on favorable
terms, if at all.

Results of  Operations

         Revenues.  During the first year after the Company  received  clearance
for the  marketing  and sale of  ALBUNEX(R)  in the United  States,  the Company
recognized revenues both on its sales to Mallinckrodt (see "Product Revenues and
License Fees," below) and on Mallinckrodt's subsequent sales to the end users of
ALBUNEX(R) (see "Revenues Under Collaborative Agreements," below).

         Revenues Under Collaborative  Agreements.  Revenues under collaborative
agreements,  which have been the primary  source of revenues  for the Company in
the past,  were $1 million and $1.4 million for the  three-month  and nine-month
periods ended December 31, 1995,  compared to $6.2 million and $14.9 million for
both of the same periods in the prior year.

         For both the  three-month  and  nine-month  periods ended  December 31,
1995, $1 million of the revenues under collaborative agreements was attributable
to the  receipt of the first  quarterly  payment  from  Mallinckrodt  to support
clinical trials (discussed above under "Liquidity and Capital  Resources").  The
remaining $13,000 and $412,000 for the same periods were based on Mallinckrodt's
sales to its customers.  Under the original Mallinckrodt contract, for the first
twelve months after the Company received  clearance for ALBUNEX(R) in the United
States,  Mallinckrodt  agreed to pay a bonus to MBI equivalent to Mallinckrodt's
first year product sales at its sales price to the end users of the product. The
Company earned $757,000 based upon the first-year product sales of ALBUNEX(R) by
Mallinckrodt.  The bonus  payment  was  received in  December  1995.  Prior year
revenues consisted of milestone  revenues  recognized as a result of the Company
receiving  approval to market ALBUNEX(R) in the United States and the release of
ALBUNEX(R) to Mallinckrodt's sales force.

         Product Revenues and License Fees.  Revenues,  excluding revenues under
collaborative  agreements,  were $232,000 and $531,000 for the  three-month  and
nine-month  periods  ended  December  31,  1995,  compared to $720,000  and $1.3
million  for the same  periods in the prior year.  Product  sales are based upon
MBI's sales to Mallinckrodt and Shionogi and are recognized upon shipment of the
product.  The transfer  price for MBI's sales of ALBUNEX(R) to  Mallinckrodt  is
equal to 40% of  Mallinckrodt's  net sales price to its end users of the product
and the transfer price for MBI's sales of ALBUNEX(R) to Shionogi is equal to 30%
of Shionogi's net sales price to its end users of the product.

         Cost of Products Sold. Cost of products sold totaled  $587,000 and $1.3
million for the  three-month  and nine-month  periods ending  December 31, 1995,
resulting  in a negative  gross  profit  margin due to the current low levels of
production. Cost of products sold totaled $988,000 for the period ended December
31, 1994,  resulting  in a gross  profit  margin of 22%. The higher gross profit
margin  percentage  in  the  prior  year  was  due to  then  greater  levels  of
production.

         Research and  Development  Costs.  For the  three-month  and nine-month
periods ended December 31, 1995,  the Company's research and  development  costs
totaled  $3.3  million and $9.9  million,  as compared to $4.3 million and $14.1
million, respectively, for the same periods in 1994. This decrease of 30% in the
current  year is due in large part to the  decision the Company made in February
1995 to focus its research and development  efforts  primarily on its ultrasound
contrast agents and reduce its staffing by approximately twenty five percent.

         Selling,  General and Administrative  Expenses. For the three-month and
nine-month periods ended December 31, 1995, the Company's  selling,  general and
administrative  expenses  totaled $1.1 million and $4.2 million,  as compared to
$1.3 million and $4.6 million,  respectively, for the same periods in 1994. This
decrease  of 10% in the current  year is also due to the  decision to reduce the
Company's staffing made in February 1995.

         Interest  Expense  and  Interest  Income.   Interest  expense  for  the
three-month and nine-month  periods ended December 31, 1995 and 1994 consists of
mortgage interest on the Company's buildings.  Interest expense is higher in the
current year due to a note payable which the Company entered into in May 1994 to
finance the purchase of two unimproved buildings and underlying land in December
1993.

         The  decrease  in interest  income in the current  year is due to lower
average cash and marketable securities balances.

         The Company's cash is invested primarily in short-term, fixed principal
investments,   such  as  U.S.   Government   agency  issues,   corporate  bonds,
certificates of deposit and commercial paper.

Prospective Information

         As noted  above,  on  September  7, 1995,  the Company  entered into an
amended and restated  distribution  agreement and a related investment agreement
with  Mallinckrodt.  This amended  distribution  agreement modifies the original
December 1988  distribution  agreement between the Company and Mallinckrodt in a
number of respects.  Under the amended distribution agreement,  the geographical
scope of  Mallinckrodt's  exclusive  right to market the  Company's  proprietary
contrast agent for transpulmonary  cardiac ultrasound imaging,  ALBUNEX(R),  the
Company's second generation  ultrasound  contrast agent,  FS069 (currently under
development),  and related products was expanded to include all of the countries
of the world other than those covered by the Company's  license  agreements with
Shionogi & Co.,  Ltd. and Nycomed AS. The duration of  Mallinckrodt's  exclusive
right was also  extended  from  October  1999 until the later of July 1, 2003 or
three years after the date that Company obtains  approval from the U.S. Food and
Drug  Administration  ("FDA")  to  market  FS069 for an  intravenous  myocardial
perfusion indication (use).

         The amended  distribution  agreement  requires  the Company to spend at
least $10  million of the $20  million it  receives  over four years on clinical
trials to support  regulatory  filings with the FDA for cardiac  indications  of
FS069. The Company's  expenditure of this $10 million will be made in accordance
with  the  directions  of a joint  steering  committee  which  the  Company  and
Mallinckrodt  will establish in order to expedite the development and regulatory
approval of FS069 by enabling the parties to share their  expertise  relating to
clinical  trials  and  the  regulatory   approval   process.   The  Company  and
Mallinckrodt  will each  appoint two of the four  members of the joint  steering
committee.

         After the Company has spent this $10 million,  the amended distribution
agreement  requires the Company and Mallinckrodt to share equally in the cost of
any  additional  clinical  trials of FS069 in the United  States which the joint
steering committee may direct to be performed,  up to a maximum of $5 million on
a combined basis.

         In addition,  the amended distribution agreement grants the Company the
option (at its own  discretion) to repurchase all of the shares of the Company's
common stock that Mallinckrodt  purchased under the investment agreement for $45
million,  subject to  various  price  adjustments.  This  option is  exercisable
beginning  the  later of July 1,  2000 or the  date  that  the  Company  obtains
approval from the FDA to market FS069 for an  intravenous  myocardial  perfusion
indication  and ending on the later of June 30,  2003 or three  years  after the
date that the  Company  obtains  approval  from the FDA to  market  FS069 for an
intravenous  myocardial  perfusion.  If the Company  exercises this option,  the
Company  may  co-market  ALBUNEX(R),  FS069 and  related  products in all of the
countries covered by the amended distribution agreement.

         Shares sold to Mallinckrodt under the related investment  agreement are
subject to certain  anti-dilution  and  registration  rights of Mallinckrodt and
certain first refusal and "standstill" rights of MBI.

         In October  1995,  the Company  entered  into an  agreement  whereby it
reaquired all rights to INFOSON (the European designation for ALBUNEX(R)), FS069
and related products from Nycomed, the Company's European licensee.  Nycomed has
received approval to market ALBUNEX(R) in Sweden, Finland and the United Kingdom
and has filed applications in several other European countries,  but has not yet
begun to market the  product.  The  Company is  currently  in  discussions  with
another  potential  licensee for Nycomed's  territory,  which  includes  Europe,
Africa,  parts of Asia and India.  Financial  terms will be disclosed at a later
date.

          Sales of  ALBUNEX(R) . In October  1993,  ALBUNEX(R)  was approved for
marketing in Japan and became the first  ultrasound  contrast agent available in
that country. As initial sales were below the Company's  expectations,  Shionogi
and the Company  engaged in an  intensive  cooperative  study of the  situation.
However, to increase the likelihood of improved sales performance in the future,
Shionogi,  with the Company's  concurrence,  decided during the first quarter of
fiscal 1995 to curtail  promotional  efforts and limit current Japanese sales to
selected  accounts  until these issues have been  resolved.  The Company has had
limited sales to Shionogi  since the second  quarter of fiscal 1995. The Company
and  Shionogi  have  recently  discussed  the  possibility  of  terminating  the
agreement between the companies. The Company believes that it is likely that the
relationship  with Shionogi will be terminated  within the next twelve months on
terms to be determined.

         In August 1994,  the Company  received  clearance for the marketing and
sale of  ALBUNEX(R)  in the United  States.  Product  sales from the  Company to
Mallinckrodt,  the  Company's  distributor  in the United  States,  totaled $1.4
million  for the first 15 months the  product  has been  marketed  in the United
States.

          President  and Chief  Operating  Officer.  In October 1995 the Company
appointed Mr. Bobba  Venkatadri as President and Chief  Operating  Officer.  Mr.
Venkatadri   most   recently   served  as  Executive   Vice   President  of  the
Pharmaceutical  Division of Centocor,  Inc.,  in Malvern,  Pennsylvania.  He was
instrumental  in  restructuring   Centocor  which  included  building  strategic
alliances, management of R&D, product approvals and scale-up of new products.

          Mr.  Venkatadri  was  appointed  to fill the  vacancy  created  by the
resignation of Vincent A. Frank.  Mr. Frank,  who served as MBI's  President and
Chief Operating Officer for 10 years, passed away in August 1995 after a lengthy
illness.

PART II - OTHER INFORMATION

Item 1-5 - The Company has nothing to report with  respect to these items during
the quarter ended December 31, 1995.

Item 6 - EXHIBITS AND REPORTS ON FORM 8-K

      (a)Exhibits - None

      (b)Reports on Form 8-K

         A  Current  Report  on Form 8-K  dated  September  7,  1995,  was filed
     on September  25,  1995,  reporting a restated  distribution  agreement and
     a related investment agreement with Mallinckrodt Medical, Inc.

      A  Current  Report  on Form 8-K  dated  November  22,  1995,  was filed on
     December 13, 1995, reporting that the arbitrator in arbitration proceedings
     between  Molecular  Biosystems,  Inc.  (the  "Company")  and Bracco  S.p.A.
     ("Bracco")  entered an award  refunding  a portion of the  license fee that
     Bracco paid to MBI in May 1993 in connection with the Company's  license to
     Bracco of MBI's oral ultrasound agent technology.

<PAGE>

SIGNATURES

Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned thereunto duly authorized.


MOLECULAR BIOSYSTEMS, INC.




/s/ Gerard A. Wills
- -------------------
Gerard A. Wills
Vice President Finance and
Chief Financial Officer


2/14/96
- -----------
Date


<TABLE> <S> <C>

<ARTICLE>                                                                 5
<LEGEND>
     This schedule  contains summary  financial  information  extracted from the
consolidated  financial statements of Molecular Biosystems,  Inc. dated December
31,  1995  and is  qualifed  in its  entirety  by  reference  to such  financial
statements.
</LEGEND>
<MULTIPLIER>                                                          1,000
       
<S>                                                       <C>
<PERIOD-TYPE>                                                         9-mos
<FISCAL-YEAR-END>                                               MAR-31-1996
<PERIOD-END>                                                    DEC-31-1995
<CASH>                                                                2,231
<SECURITIES>                                                         18,889
<RECEIVABLES>                                                           435
<ALLOWANCES>                                                              0
<INVENTORY>                                                             697
<CURRENT-ASSETS>                                                     22,716
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<DEPRECIATION>                                                        6,773
<TOTAL-ASSETS>                                                       45,728
<CURRENT-LIABILITIES>                                                 4,203
<BONDS>                                                               8,183
<COMMON>                                                                133
                                                     0
                                                               0
<OTHER-SE>                                                           33,209
<TOTAL-LIABILITY-AND-EQUITY>                                         45,728
<SALES>                                                                 506
<TOTAL-REVENUES>                                                      1,943
<CGS>                                                                 1,311
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<OTHER-EXPENSES>                                                          0
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<INCOME-PRETAX>                                                     (16,297)
<INCOME-TAX>                                                              0
<INCOME-CONTINUING>                                                 (16,297)
<DISCONTINUED>                                                            0
<EXTRAORDINARY>                                                           0
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<NET-INCOME>                                                        (16,297)
<EPS-PRIMARY>                                                        (1.300)
<EPS-DILUTED>                                                         0.000
        


</TABLE>


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