MOLECULAR BIOSYSTEMS INC
8-K, 2000-01-11
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549



                                    FORM 8-K



                                 CURRENT REPORT


       Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934



         Date of Report (date of earliest event reported): January 5, 2000



                           MOLECULAR BIOSYSTEMS, INC.
             (Exact name of registrant as specified in its charter)



          Delaware                 1-10546                  36-3078632
(State of Incorporation)  (Commission File Number)   (I.R.S. Identification No.)



              10030 Barnes Canyon Road, San Diego, California 92121
                    (Address of principal executive offices)



        Registrant's telephone number, including area code: (858) 812-7001








<PAGE>



Item 5.  Other Events


Molecular Biosystems to be Quoted on the NASD Over-The-Counter Bulletin Board.


          Effective January 5, 2000, trading of Molecular Biosystems,  Inc. (the
"Company") common stock was moved to the NASD Over-The-Counter Bulletin Board. A
new trading  symbol of "MBIO" was  assigned to the Company by NASD.  The Company
had  previously  traded on the New York Stock  Exchange  under the  symbol  "MB"
through the close of business January 4, 2000.



Item 7.  Financial Statements and Exhibits

         10.1              Press release dated December 28, 1999.








<PAGE>





SIGNATURES

Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned thereunto duly authorized.


MOLECULAR BIOSYSTEMS, INC.




/s/ Elizabeth Hougen
Elizabeth Hougen
Executive Director, Finance and Chief Financial Officer
(Principal Financial and Accounting Officer)


1/6/00




<PAGE>



                                  Exhibit Index

    Exhibit                Description

    10.1                   Press release dated December 28, 1999.






<PAGE>




Exhibit 10.1




Contacts:
Elizabeth Hougen, Chief Financial Officer (858) 812-7179
Patricia Sullivan, Manager, Investor Relations (858) 812-7146
E-Mail: [email protected]


                         MBI Plans for Listing on NASD's
                         Over-The-Counter Bulletin Board

San Diego, California,  December 28, 1999 - Molecular Biosystems, Inc. announced
today  that  trading of its common  stock  will  continue  on the New York Stock
Exchange  until the close of business on Tuesday,  January 4, 2000. The date was
extended from  December 30, 1999, in order to effectuate an orderly  transition.
Effective  Wednesday,  January 5, 2000,  MBI's  common  stock is  expected to be
quoted on NASD's  Over-The-Counter  Bulletin  Board.  A trading  symbol  will be
assigned when listing commences.

MBI, based in San Diego,  California,  is a world leader in developing  contrast
agents for diagnostic  imaging.  Its innovative  product,  OPTISON(R),  improves
diagnosis of heart disease through clearer ultrasound images.

This news release  contains  forward-looking  statements  that involve risks and
uncertainties.  Among the factors that could  result in a  materially  different
outcome  are:  MBI's  failure to be quoted on NASD's  Over-The-Counter  Bulletin
Board and other risk factors  reported  from time to time in MBI's  filings with
the Securities and Exchange Commission.

       For More Information on Molecular Biosystems by Fax, Dial 888-329-4007,
                       or Visit its Web site: www.mobi.com




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