CARDINAL HEALTH INC
S-8 POS, 1996-05-08
DRUGS, PROPRIETARIES & DRUGGISTS' SUNDRIES
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<PAGE>


        As filed with the Securities and Exchange Commission on May 8, 1996

                                               Registration No. 333-01927-01
______________________________________________________________________________
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
                                 _______________

                            POST-EFFECTIVE AMENDMENT
                                      NO. 1
                                       ON
                                    FORM S-8
                                       TO
                                    FORM S-4
                             REGISTRATION STATEMENT
                                      Under
                           The Securities Act of 1933*
                                 _______________

                              Cardinal Health, Inc.
             (Exact name of registrant as specified in its charter)

                      Ohio                           31-0958666
          (State or other jurisdiction  (I.R.S. Employer Identification No.)
        of incorporation or organization)

        5555 Glendon Court, Dublin, Ohio                43016
    (Address of Principal Executive Offices)         (Zip Code)
                                _______________
                      AMENDED AND RESTATED 1991 STOCK PLAN
                              OF PYXIS CORPORATION
                            (Full title of the plan)
                                _______________

                            George H. Bennett, Jr.,
            Executive Vice President, Secretary and General Counsel
                             Cardinal Health, Inc.
                               5555 Glendon Court
                              Dublin, Ohio  43016
                    (Name and address of agent for service)

                                 (614) 717-5000
         (Telephone number, including area code, of agent for service)
                                _______________

                        CALCULATION OF REGISTRATION FEE
______________________________________________________________________________

Title of       Amount        Proposed           Proposed          Amount of
securities to  to be         maximum offering   maximum aggregate registration
be registered  registered(1) price per share(1) offering price    fee          
______________________________________________________________________________
Common Shares,
without par 
value          1,565,000          (2)              (2)              (2)        
______________________________________________________________________________ 

(1)  Also includes an indeterminable number of additional shares that may
     become issuable pursuant to the anti-dilution provisions of the Plan.
(2)  Not applicable.  All filing fees payable in connection with the
     registration of the issuance of these securities were paid in connection
     with the filing of (a) preliminary proxy materials on Schedule 14A of
     Pyxis Corporation on March 8, 1996, and (b) the Registrant's Form S-4
     Registration Statement (333-01927) on March 25, 1996.
*    Filed as a Post-Effective Amendment on Form S-8 to such Form S-4
     Registration Statement pursuant to the procedure described in Part II
     under "Introductory Statement."<PAGE>







                                     PART II

                INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

                              INTRODUCTORY STATEMENT

                   Cardinal Health, Inc. (the "Company" or the "Regis-
         trant") hereby amends its Registration Statement on Form S-4
         (No. 333-01927) (the "Form S-4") by filing this Post-Effective
         Amendment No. 1 on Form S-8 ("Amendment No. 1") with respect to
         up to 1,565,000 of the Registrant's Common Shares, without par
         value ("Common Shares"), issuable in connection with the
         Amended and Restated 1991 Stock Plan (the "Plan") of Pyxis
         Corporation ("Pyxis").  All such Common Shares were previously
         included in the Form S-4.

                   On May 7, 1996, Aztec Merger Corp., a Delaware corpo-
         ration and a wholly owned subsidiary of the Registrant ("AMC"),
         was merged with and into Pyxis (the "Merger") pursuant to an
         Agreement and Plan of Merger dated February 7, 1996, among the
         Registrant, AMC and Pyxis (the "Merger Agreement").  As a
         result of the Merger, each outstanding share of Pyxis Common
         Stock (with certain specified exceptions) was converted into
         Common Shares of the Registrant pursuant to the exchange ratio
         (the "Exchange Ratio") set forth in the Merger Agreement.  Also
         as a result of the Merger, shares of Pyxis Common Stock are no
         longer issuable upon the exercise of options to purchase Pyxis
         Common Stock ("Pyxis Options") pursuant to the Plan.  Instead,
         participants in the Plan will receive in lieu of Pyxis Common
         Stock that number of Common Shares of the Registrant equal to
         the number of shares of Pyxis Common Stock issuable immediately
         prior to the effective time of the Merger upon exercise of a
         Pyxis Option multiplied by the Exchange Ratio, with an exercise
         price for such option equal to the exercise price which existed
         under the corresponding Pyxis Option divided by the Exchange
         Ratio.

                   The designation of Amendment No. 1 as Registration
         No. 333-01927-01 denotes that Amendment No. 1 relates only to
         the Common Shares issuable pursuant to the Plan and that this
         is the first Post-Effective Amendment to the S-4 filed with
         respect to such shares.

         ITEM 3.   INCORPORATION OF DOCUMENTS BY REFERENCE.

                   The documents listed below are incorporated by refer-
         ence in the registration statement.  All documents filed by the
         Company pursuant to Sections 13(a), 13(c), 14 and 15(d) of the
         Securities Exchange Act of 1934, as amended (the "Exchange<PAGE>







         Act"), subsequent to the date of the filing of this registra-
         tion statement and prior to the filing of a post-effective
         amendment that indicates that all securities registered hereun-
         der have been sold, or that de-registers all securities then
         remaining unsold, shall be deemed to be incorporated by refer-
         ence in the registration statement and to be a part hereof from
         the date of the filing of such documents.

              (a)  The Annual Report on Form 10-K of the Company for the
         fiscal year ended June 30, 1995 filed with the Commission on
         September 21, 1995;

              (b)  The Company's Current Report on Form 8-K dated
         August 26, 1995;

              (c)  The Company's Current Report on Form 8-K dated
         October 23, 1995;

              (d)  The Company's Quarterly Report on Form 10-Q for the
         quarter ended September 30, 1995 filed with the Commission on
         November 6, 1995;

              (e)  The Company's Current Report on Form 8-K dated Novem-
         ber 13, 1995, as amended by the Company's Current Report on
         Form 8-K/A filed January 18, 1996;

              (f)  The Company's Current Report on Form 8-K dated Janu-
         ary 10, 1996;

              (g)  The Company's Quarterly Report on Form 10-Q for the
         quarter ended December 31, 1995 filed with the Commission on
         February 12, 1996;

              (h)  The Company's Current Report on Form 8-K dated April
         22, 1996; 

              (i)  The Company's Quarterly Report on Form 10-Q for the
         quarter ended March 31, 1996 filed with the Commission on May
         3, 1996; 

              (j)  The Company's Current Report on Form 8-K dated May 7,
         1996; and

              (k)  The description of the Company's Common Shares con-
         tained in the Company's Registration Statement on Form 8-A
         dated August 19, 1994, pursuant to Section 12 of the Exchange
         Act.







                                       -2-<PAGE>







         ITEM 5.   INTEREST OF NAMED EXPERTS AND COUNSEL.

                   The legality of the Common Shares offered hereby has
         been passed upon for the Company by Paul S. Williams, Assistant
         General Counsel of the Company.  Mr. Williams holds unvested
         options to purchase Common Shares of the Company. 

         ITEM 6.   INDEMNIFICATION OF DIRECTORS AND OFFICERS.

                   Section 1701.13(E) of the Ohio Revised Code sets
         forth conditions and limitations governing the indemnification
         of officers, directors, and other persons.

                   Article 6 of the Company's Restated Code of Regula-
         tions ("Code of Regulations"), as amended, contains certain
         indemnification provisions adopted pursuant to authority con-
         tained in Section 1701.13(E) of the Ohio Revised Code.  The
         Company's Code of Regulations provides for the indemnification
         of its officers, directors, employees, and agents against all
         expenses with respect to any judgments, fines, and amounts paid
         in settlement, or with respect to any threatened, pending, or
         completed action, suit, or proceeding to which they were or are
         parties or are threatened to be made parties by reason of act-
         ing in such capacities, provided that it is determined, either
         by a majority vote of a quorum of disinterested directors of
         the Company or the shareholders of the Company or otherwise as
         provided in Section 1701.13(E) of the Ohio Revised Code, that
         (a) they acted in good faith and in a manner they reasonably
         believed to be in or not opposed to the best interest of the
         Company; (b) in any action, suit, or proceeding by or in the
         right of the Company, they were not, and have not been adjudi-
         cated to have been, negligent or guilty of misconduct in the
         performance of their duties to the Company; and (c) with
         respect to any criminal action or proceeding, that they had no
         reasonable cause to believe that their conduct was unlawful.
         Section 1701.13(E) provides that to the extent a director,
         officer, employee, or agent has been successful on the merits
         or otherwise in defense of any such action, suit, or proceed-
         ing, he shall be indemnified against expenses reasonably
         incurred in connection therewith.  At present there are no
         material claims, actions, suits, or proceedings pending where
         indemnification would be required under these provisions, and
         the Company does not know of any such threatened claims,
         actions, suits, or proceedings which may result in a request
         for such indemnification.

                   The Company has entered into indemnification con-
         tracts with each of its directors and executive officers.
         These contracts generally:  (i) confirm the existing indemnity
         provided to them under the Company's Code of Regulations and 



                                       -3-<PAGE>







         assure that this indemnity will continue to be provided; (ii)
         provide that if the Company does not maintain directors' and
         officers' liability insurance, the Company will, in effect,
         become a self-insurer of the coverage; and (iii) provide that,
         in addition, the directors and officers shall be indemnified to
         the fullest extent permitted by law against all expenses
         (including legal fees), judgments, fines, and settlement
         amounts paid or incurred by them in any action or proceeding,
         including any action by or in the right of the Company, on
         account of their service as a director, officer, employee, or
         agent of the Company or at the request of the Company as a
         director, officer, employee, or agent of another corporation or
         enterprise.  Coverage under the contracts is excluded:  (A) on
         account of conduct which is finally adjudged to be knowingly
         fraudulent, deliberately dishonest, or willful misconduct; or
         (B) if a final court of adjudication shall determine that such
         indemnification is not lawful; or (C) in respect of any suit in
         which judgment is rendered for violations of Section 16(b) of
         the Exchange Act or similar provisions of any federal, state,
         or local statutory law; or (D) on account of any remuneration
         paid which is finally adjudged to have been in violation of
         law; or (E) as to officers who are not directors, with respect
         to any act or omission which is finally adjudged to have been a
         violation, other than in good faith, of the Company's Standards
         of Business Conduct of which the officer then most recently has
         received written notice.  The indemnification agreements are
         applicable to claims asserted after their effective date,
         whether arising from acts or omissions occurring before or
         after their effective date, and associated legal expenses.

         ITEM 8.   EXHIBITS.

         Exhibit Number          Description of Exhibit
         _____________           ______________________

               5         Opinion of Paul S. Williams as to legality of
                         the Common Shares being registered

             23(a)       Consent of Deloitte & Touche LLP

             23(b)       Consent of Arthur Andersen LLP -- Sacramento

             23(c)       Consent of Arthur Andersen LLP -- St. Louis

             23(d)       Consent of Ernst & Young LLP

             23(e)       Consent of Paul S. Williams (included in
                         Opinion filed as Exhibit 5 hereto)

              24         Power of attorney (included on the Signature
                         Page of this Form S-8)

              99         Amended and Restated 1991 Stock Plan of Pyxis
                         Corporation


                                       -4-<PAGE>







         ITEM 9.   UNDERTAKINGS.

                   A.   The undersigned Registrant hereby undertakes:

                        (1)  To file, during any period in which offers
         or sales are being made, a post-effective amendment to this
         registration statement: (i) to include any prospectus required
         by Section 10(a)(3) of the Securities Act of 1933, as amended
         (the "Securities Act"); (ii) to reflect in the prospectus any
         facts or events arising after the effective date of the regis-
         tration statement (or the most recent post-effective amendment
         thereof) which, individually or in the aggregate, represent a
         fundamental change in the information set forth in the regis-
         tration statement; and (iii) to include any material informa-
         tion with respect to the plan of distribution not previously
         disclosed in the registration statement or any material change
         to such information in the registration statement; provided,
         however, that clauses (i) and (ii) do not apply if the informa-
         tion required to be included in a post-effective amendment by
         those clauses is contained in periodic reports filed with or
         furnished to the Securities and Exchange Commission by the
         Registrant pursuant to Section 13 or Section 15(d) of the
         Exchange Act that are incorporated by reference in the regis-
         tration statement;

                        (2)  That, for the purpose of determining any
         liability under the Securities Act, each such post-effective
         amendment shall be deemed to be a new registration statement
         relating to the securities offered therein, and the offering of
         such securities at that time shall be deemed to be the initial
         bona fide offering thereof; and

                        (3)  To remove from registration by means of a
         post-effective amendment any of the securities being registered
         which remain unsold at the termination of the offering.

                   B.   The undersigned registrant hereby undertakes
         that, for purposes of determining any liability under the Secu-
         rities Act, each filing of the Registrant's annual report pur-
         suant to Section 13(a) or Section 15(d) of the Exchange Act
         that is incorporated by reference in the registration statement
         shall be deemed to be a new registration statement relating to
         the securities offered therein, and the offering of such secu-
         rities at that time shall be deemed to be the initial bona fide
         offering thereof.

                   C.   Insofar as indemnification for liabilities aris-
         ing under the Securities Act may be permitted to directors,
         officers and controlling persons of the Registrant pursuant to
         the provisions described under Item 6 above or otherwise, the 



                                       -5-<PAGE>







         Registrant has been advised that in the opinion of the Securi-
         ties and Exchange Commission such indemnification is against
         public policy as expressed in the Securities Act and is, there-
         fore, unenforceable.  In the event that a claim for indemnifi-
         cation against such liabilities (other than the payment by the
         Registrant of expenses incurred or paid by a director, officer
         or controlling person of the Registrant in the successful
         defense of any action, suit or proceeding) is asserted by such
         director, officer or controlling person in connection with the
         securities being registered, the Registrant will, unless in the
         opinion of its counsel the matter has been settled by control-
         ling precedent, submit to a court of appropriate jurisdiction
         the question whether such indemnification by it is against pub-
         lic policy as expressed in the Securities Act and will be
         governed by the final adjudication of such issue.







































                                       -6-<PAGE>







                                    SIGNATURES

                   Pursuant to the requirements of the Securities Act of
         1933, the Registrant certifies that it has reasonable grounds
         to believe that it meets all of the requirements for filing on
         Form S-8 and has duly caused this registration statement to be
         signed on its behalf by the undersigned, thereunto duly autho-
         rized, in the City of Dublin, State of Ohio, on the 8th day of
         May, 1996.


                                       CARDINAL HEALTH, INC.


                                       By: /s/ Robert D. Walter         
                                          ______________________________
                                           Robert D. Walter, Chairman
                                           and Chief Executive Officer


                   KNOW ALL MEN BY THESE PRESENTS, that each person
         whose signature appears below constitutes and appoints Robert
         D. Walter, George H. Bennett, Jr., and Paul S. Williams, and
         each of them, severally, as his/her attorney-in-fact and agent,
         with full power of substitution and resubstitution, for him/her
         and in his/her name, place, and stead, in any and all capaci-
         ties, to sign any and all pre- or post-effective amendments to
         this Registration Statement, and to file the same with all
         exhibits hereto, and other documents with the Securities and
         Exchange Commission, granting unto said attorney-in-fact and
         agent, and each of them, full power and authority to do and
         perform each and every act and thing requisite or necessary to
         be done in and about the premises, as fully to all intents and
         purposes as he/she might or could do in person, hereby ratify-
         ing and confirming all that said attorneys-in-fact and agents,
         or any of them, or their or his substitutes, may lawfully do or
         cause to be done by virtue hereof.

                   Pursuant to the requirements of the Securities Act of
         1933, this registration statement has been signed by the fol-
         lowing persons in the capacities indicated on the 8th day of
         May, 1996.


         Signature                          Title


         /s/ Robert D. Walter               Chairman and Chief Executive
         ___________________________        Officer (principal executive
         Robert D. Walter                   officer)




                                       -7-<PAGE>







         /s/ David Bearman                  Executive Vice President and
         ___________________________        Chief Financial Officer and
         David Bearman                      Chief Accounting Officer


         /s/ John F. Finn                   Director
         ___________________________
         John F. Finn


         /s/ Robert L. Gerbig               Director
         ___________________________
         Robert L. Gerbig


         /s/ John F. Havens                 Director
         ___________________________
         John F. Havens


         /s/ Regina E. Herzlinger           Director
         ___________________________
         Regina E. Herzlinger


         /s/ John C. Kane                   Director
         ___________________________
         John C. Kane


         /s/ George R. Manser               Director
         ___________________________
         George R. Manser


         /s/ John B. McCoy                  Director
         ___________________________
         John B. McCoy


         /s/ Jerry E. Robertson             Director
         ___________________________
         Jerry E. Robertson


         /s/ L. Jack Van Fossen             Director
         ___________________________
         L. Jack Van Fossen


         /s/ Melburn G. Whitmire            Director
         ___________________________
         Melburn G. Whitmire


                                       -8-<PAGE>







                                  EXHIBIT INDEX
                                  _____________

         EXHIBIT NUMBER               EXHIBIT DESCRIPTION
         ______________               ___________________

               5           Opinion of Paul S. Williams as to legality of
                           the Common Shares being registered

             23(a)         Consent of Deloitte & Touche LLP

             23(b)         Consent of Arthur Andersen LLP -- Sacramento

             23(c)         Consent of Arthur Andersen LLP -- St. Louis

             23(d)         Consent of Ernst & Young LLP

             23(e)         Consent of Paul S. Williams (included in
                           Opinion filed as Exhibit 5 hereto)

              24           Power of Attorney (included on the Signature
                           Page of this Form S-8)

              99           Amended and Restated 1991 Stock Plan of Pyxis
                           Corporation<PAGE>







                                                              EXHIBIT 5


                                            May 8, 1996



         Cardinal Health, Inc.
         5555 Glendon Court
         Dublin, OH  43016

         Gentlemen:

                   I have acted as counsel to Cardinal Health, Inc., an
         Ohio corporation (the "Company"), in connection with Post-
         Effective Amendment No. 1 on Form S-8 to the Company's Regis-
         tration Statement on Form S-4 (the "Registration Statement")
         filed under the Securities Act of 1933 (the "Act") relating to
         the issuance of up to 1,565,000 Common Shares, without par
         value (the "Common Shares"), of the Company pursuant to the
         Amended and Restated 1991 Stock Plan of Pyxis Corporation (the
         Plan).

                   In connection with the foregoing, I have examined:
         (a) the Amended and Restated Articles of Incorporation, as
         amended, and Restated Code of Regulations, as amended, of the
         Company, (b) the Plan, and (c) such records of the corporate
         proceedings of the Company and such other documents as I deemed
         necessary to render this opinion.

                   Based on such examination, I am of the opinion that
         the Common Shares available for issuance under the Plan, when
         issued, delivered and paid for in accordance with the terms and
         conditions of the Plan, will be legally issued, fully paid and
         nonassessable.

                   I hereby consent to the filing of this Opinion as
         Exhibit 5 to the Registration Statement and the reference to me
         in Item 5 of Part II of the Registration Statement.

                                            Very truly yours,

                                            /s/ Paul S. Williams

                                            Paul S. Williams, Esq.<PAGE>







                                                          EXHIBIT 23(A)


         INDEPENDENT AUDITORS' CONSENT

         We consent to the incorporation by reference in this Registra-
         tion Statement of Cardinal Health, Inc. on Form S-8 filed as
         Post Effective Amendment No. 1 to Form S-4 Registration State-
         ment No. 333-01927 of our report dated August 14, 1995, except
         for Note 16, as to which the date is August 26, 1995 (which
         report expresses an unqualified opinion and includes an
         explanatory paragraph relating to the change in method of
         accounting for income taxes), appearing in the Annual Report on
         Form 10-K of Cardinal Health, Inc. for the year ended June 30,
         1995, and of our report dated January 5, 1996 (which report
         expresses an unqualified opinion and includes an explanatory
         paragraph relating to the change in method of accounting for
         income taxes), appearing in Form 8-K of Cardinal Health, Inc.
         dated January 10, 1996.

         /s/ Deloitte & Touche LLP

         DELOITTE & TOUCHE LLP

         Columbus, Ohio
         May 3, 1996<PAGE>







                                                          EXHIBIT 23(B)


         CONSENT OF INDEPENDENT PUBLIC ACCOUNTANTS

         As independent public accountants, we hereby consent to incor-
         poration by reference in this Registration Statement of Cardi-
         nal Health, Inc. on Form S-8 filed as Post Effective Amendment
         No. 1 to Form S-4 Registration Statement No. 333-01927 of our
         report on Whitmire Distribution Corporation for the year ended
         July 3, 1993, dated September 3, 1993, included in Cardinal
         Health, Inc.'s Form 10K for the year ended June 30, 1995, and
         in Cardinal Health, Inc.'s Form 8-K dated January 10, 1996, and
         to all references to our Firm included in this registration
         statement.

         /s/ Arthur Andersen LLP

         Arthur Andersen LLP

         Sacramento, California
         May 3, 1996<PAGE>







                                                          EXHIBIT 23(C)


         CONSENT OF INDEPENDENT PUBLIC ACCOUNTANTS

         As independent public accountants, we hereby consent to incor-
         poration by reference in this Registration Statement of Cardi-
         nal Health, Inc. on Form S-8 filed as Post Effective Amendment
         No. 1 to Form S-4 Registration Statement No. 333-01927 of our
         report on Medicine Shoppe International, Inc. dated November 4,
         1994, included in Cardinal Health, Inc.'s Form 8-K dated Novem-
         ber 16, 1995, and to all references to our Firm included in
         this registration statement.

         /s/ Arthur Andersen LLP

         Arthur Andersen LLP

         St. Louis, Missouri
         May 3, 1996<PAGE>







                                                          EXHIBIT 23(D)


         CONSENT OF ERNST & YOUNG LLP, INDEPENDENT AUDITORS

         We consent to the incorporation by reference in the Registra-
         tion Statement (Post Effective Amendment No. 1 on Form S-8 to
         Form S-4 No. 333-01927-01) of Cardinal Health, Inc. pertaining
         to the Amended and Restated 1991 Stock Plan of Pyxis Corpora-
         tion of our report dated January 30, 1996, except for Note 6,
         Note 7 ("Stockholder Rights Plan"), and Note 13, for which the
         date is February 7, 1996, with respect to the consolidated
         financial statements of Pyxis Corporation included in the Cur-
         rent Report on Form 8-K of Cardinal Health, Inc., filed with
         the Securities and Exchange Commission.

                                            /s/ Ernst & Young LLP

                                            ERNST & YOUNG LLP

         San Diego, California
         May 3, 1996<PAGE>







                                                             EXHIBIT 99


                     AMENDED AND RESTATED 1991 STOCK PLAN OF

                                PYXIS CORPORATION


         SECTION 1.  Establishment and Purpose.


                   The Plan was established on March 25, 1991, to offer
         directors and selected employees, advisors and consultants an
         opportunity to acquire a proprietary interest in the success of
         the Company, or to increase such interest, by purchasing Shares
         of the Company's Common Stock.  The Plan was most recently
         amended and restated by the Board of Directors on January 30,
         1995, to, among other things, increase the number of shares
         available for grants, which amendment and restatement was ap-
         proved by the Company's stockholders on May 25, 1995.  The Plan
         provides both for the direct award or sale of Shares and for
         the grant of Options to purchase Shares.  Options granted under
         the Plan may include Nonstatutory Options as well as ISO's in-
         tended to qualify under section 422 of the Code.


                   The Plan is intended to comply in all respects with
         Rule 16b-3 (or its successor) under the Exchange Act and shall
         be construed accordingly.


         SECTION 2.  Definitions.


                   (a)  "Board of Directors" shall mean the Board of
         Directors of the Company, as constituted from time to time.


                   (b)  "Change in Control" shall mean the occurrence of
         either of the following events:


                        (i)  A change in the composition of the Board of
                   Directors, as a result of which fewer than one-half
                   of the incumbent directors are directors who either:


                             (A)  Had been directors of the Company
                        24 months prior to such change; or<PAGE>







                             (B)  Were elected, or nominated for
                        election, to the Board of Directors with the
                        affirmative votes of at least a majority of the
                        directors who had been directors of the Company
                        24 months prior to such change and who were
                        still in office at the time of the election or
                        nomination; or


                       (ii)  Any "person" (as such term is used in sec-
                   tions 13(d) and 14(d) of the Exchange Act) by the
                   acquisition or aggregation of securities is or be-
                   comes the beneficial owner, directly or indirectly,
                   of securities of the Company representing 50 percent
                   or more of the combined voting power of the Company's
                   then outstanding securities ordinarily (and apart
                   from rights accruing under special circumstances)
                   having the right to vote at elections of directors
                   (the "Base Capital Stock"); except that any change in
                   the relative beneficial ownership of the Company's
                   securities by any person resulting solely from a re-
                   duction in the aggregate number of outstanding shares
                   of Base Capital Stock, and any decrease thereafter in
                   such person's ownership of securities, shall be dis-
                   regarded until such person increases in any manner,
                   directly or indirectly, such person's beneficial own-
                   ership of any securities of the Company.


                   (c)  "Code" shall mean the Internal Revenue Code
         of 1986, as amended.


                   (d)  "Committee" shall mean a committee of the Board
         of Directors, as described in Section 3(a).


                   (e)  "Company" shall mean Pyxis Corporation, a
         Delaware corporation.


                   (f)  "Employee" shall mean (i) any individual who is
         a common-law employee of the Company or of a Subsidiary, (ii)
         an Outside Director and (iii) an independent contractor who
         performs services for the Company or a Subsidiary and who is
         not a member of the Board of Directors.  Service as an Outside
         Director or independent contractor shall be considered employ-
         ment for all purposes of the Plan, except as provided in Sub-
         sections (a) and (b) of Section 4.





                                       -2-<PAGE>







                   (g)  "Exchange Act" shall mean the Securities
         Exchange Act of 1934, as amended.


                   (h)  "Exercise Price" shall mean the amount for which
         one Share may be purchased upon exercise of an Option, as spec-
         ified by the Committee in the applicable Stock Option Agree-
         ment.


                   (i)  "Fair Market Value" shall mean the market price
         of Stock, determined by the Committee as follows:


                        (i)  If Stock was traded over-the-counter on the
                   date in question but was not traded on the Nasdaq
                   Stock Market or the Nasdaq National Market, then the
                   Fair Market Value shall be equal to the mean between
                   the last reported representative bid and asked prices
                   quoted for such date by the principal automated
                   inter-dealer quotation system on which stock is
                   quoted or, if the stock is not quoted on any such
                   system, by the "Pink Sheets" published by the
                   National Quotation Bureau, Inc.;


                       (ii)  If Stock was traded over-the-counter on the
                   date in question and was traded on the Nasdaq Stock
                   Market or the Nasdaq National Market, then the Fair
                   Market Value shall be equal to the last-transaction
                   price quoted for such date by the Nasdaq Stock Market
                   or the Nasdaq National Market;


                      (iii)  If Stock was traded on a stock exchange on
                   the date in question, then the Fair Market Value
                   shall be equal to the closing price reported by the
                   applicable composite-transactions report for such
                   date; and


                       (iv)  If none of the foregoing provisions is ap-
                   plicable, then the Fair Market Value shall be deter-
                   mined by the Committee in good faith on such basis as
                   it deems appropriate.


         In all cases, the determination of Fair Market Value by the
         Committee shall be conclusive and binding on all persons.





                                       -3-<PAGE>







                   (j)  "ISO" shall mean an employee incentive stock
         option described in section 422(b) of the Code.


                   (k)  "Nonstatutory Option" shall mean a stock option
         not described in sections 422(b) or 423(b) of the Code.


                   (l)  "Offeree" shall mean an individual to whom the
         Committee has offered the right to acquire Shares under the
         Plan (other than upon exercise of an Option).


                   (m)  "Option" shall mean an ISO or Nonstatutory
         Option granted under the Plan and entitling the holder to pur-
         chase Shares.


                   (n)  "Optionee" shall mean an individual who holds an
         Option.


                   (o)  "Outside Director" shall mean a member of the
         Board of Directors who is not a common-law employee of the
         Company or of a Subsidiary.


                   (p)  "Plan" shall mean this 1991 Stock Plan of Pyxis
         Corporation.


                   (q)  "Purchase Price" shall mean the consideration
         for which one Share may be acquired under the Plan (other than
         upon exercise of an Option), as specified by the Committee.


                   (r)  "Service" shall mean service as an Employee.


                   (s)  "Share" shall mean one share of Stock, as ad-
         justed in accordance with Section 9 (if applicable).


                   (t)  "Stock" shall mean the Common Stock of the
         Company.


                   (u)  "Stock Option Agreement" shall mean the agree-
         ment between the Company and an Optionee which contains the
         terms, conditions and restrictions pertaining to his or her
         Option.



                                       -4-<PAGE>







                   (v)  "Stock Purchase Agreement" shall mean the agree-
         ment between the Company and an Offeree who acquires Shares
         under the Plan which contains the terms, conditions and re-
         strictions pertaining to the acquisition of such Shares.


                   (w)  "Subsidiary" shall mean any corporation, if the
         Company and/or one or more other Subsidiaries own not less than
         50 percent of the total combined voting power of all classes of
         outstanding stock of such corporation.  A corporation that at-
         tains the status of a Subsidiary on a date after the adoption
         of the Plan shall be considered a Subsidiary commencing as of
         such date.


                   (x)  "Total and Permanent Disability" shall mean that
         the Optionee is unable to engage in any substantial gainful
         activity by reason of any medically determinable physical or
         mental impairment which can be expected to result in death or
         which has lasted, or can be expected to last, for a continuous
         period of not less than one year.


         SECTION 3.  Administration.


                   (a)  Committee Membership.  The Plan shall be admin-
         istered by the Committee.  The Committee shall consist of two
         or more disinterested directors of the Company and shall meet
         such other requirements as may be established from time to time
         by the Securities and Exchange Commission for plans intended to
         qualify for exemption under Rule 16b-3 (or its successor) under
         the Exchange Act.  The Board of Directors may appoint a separ-
         ate committee of the Board of Directors, composed of one or
         more directors of the Company who need not be disinterested
         directors, who may administer the Plan with respect to
         Employees who are not officers or directors of the Company, may
         grant Shares and Options under the Plan to such Employees and
         may determine the timing, number of Shares and other terms of
         such grants.


                   (b)  Disinterested Directors.  A member of the Board
         of Directors shall be deemed "disinterested" only if he or she
         satisfies (i) such requirements as the Securities and Exchange
         Commission may establish for disinterested administrators of
         plans designed to qualify for exemption under Rule 16b-3 (or
         its successor) under the Exchange Act and (ii) such require-
         ments as the Internal Revenue Service may establish for outside
         directors acting under plans intended to qualify for exemption 




                                       -5-<PAGE>







         under section 162(m)(4)(C) of the Code.  An Outside Director
         shall not fail to be "disinterested" solely because he or she
         receives the Nonstatutory Options described in Section 4(b).


                   (c)  Committee Procedures.  The Committee shall
         designate one of its members as chairman.  The Committee may
         hold meetings at such times and places as it shall determine.
         The acts of a majority of the Committee members present at
         meetings at which a quorum exists, or acts reduced to or
         approved in writing by all Committee members, shall be valid
         acts of the Committee.


                   (d)  Committee Responsibilities.  Subject to the pro-
         visions of the Plan, the Committee shall have full authority
         and discretion to take the following actions:


                        (i)  To interpret the Plan and to apply its pro-
                   visions;


                       (ii)  To adopt, amend or rescind rules, proce-
                   dures and forms relating to the Plan;


                      (iii)  To authorize any person to execute, on be-
                   half of the Company, any instrument required to carry
                   out the purposes of the Plan;


                       (iv)  To determine when Shares are to be awarded
                   or offered for sale and when Options are to be
                   granted under the Plan;


                        (v)  To select the Offerees and Optionees;


                       (vi)  To determine the number of Shares to be
                   offered to each Offeree or to be made subject to each
                   Option;


                      (vii)  To prescribe the terms and conditions of
                   each award or sale of Shares, including (without lim-
                   itation) the Purchase Price, and to specify the pro-
                   visions of the Stock Purchase Agreement relating to
                   such award or sale;




                                       -6-<PAGE>







                     (viii)  To prescribe the terms and conditions of
                   each Option, including (without limitation) the Exer-
                   cise Price, to determine whether such Option is to be
                   classified as an ISO or as a Nonstatutory Option, and
                   to specify the provisions of the Stock Option Agree-
                   ment relating to such Option;


                       (ix)  To amend any outstanding Stock Purchase
                   Agreement or Stock Option Agreement, subject to
                   applicable legal restrictions and to the consent of
                   the Offeree or Optionee who entered into such
                   agreement;


                        (x)  To prescribe the consideration for the
                   grant of each Option or other right under the Plan
                   and to determine the sufficiency of such consider-
                   ation; and


                       (xi)  To take any other actions deemed necessary
                   or advisable for the administration of the Plan.


         All decisions, interpretations and other actions of the Commit-
         tee shall be final and binding on all Offerees, all Optionees,
         and all persons deriving their rights from an Offeree or
         Optionee.  No member of the Committee shall be liable for any
         action that he or she has taken or has failed to take in good
         faith with respect to the Plan, any Option, or any right to
         acquire Shares under the Plan.


         SECTION 4.  Eligibility.


                   (a)  General Rules.  Only Employees (including, with-
         out limitation, independent contractors who are not members of
         the Board of Directors) shall be eligible for designation as
         Optionees or Offerees by the Committee.  In addition, only Em-
         ployees who are common-law employees of the Company or a Sub-
         sidiary shall be eligible for the grant of ISO's.  Employees
         who are Outside Directors shall only be eligible for the grant
         of the Nonstatutory Options described in Subsection (b) below.


                   (b)  Outside Directors.  Any other provision of the
         Plan notwithstanding, the participation of Outside Directors in
         the Plan shall be subject to the following restrictions:




                                       -7-<PAGE>







                        (i)  Outside Directors shall receive no grants
                   other than the Nonstatutory Options described in this
                   Subsection (b).


                       (ii)  Each Outside Director who first becomes a
                   member of the Board of Directors after the effective
                   date of the Company's registration statement on Form
                   8-A under the Exchange Act shall receive a one-time
                   grant of a Nonstatutory Option covering 10,000 Shares
                   (subject to adjustment under Article 9).  Such Non-
                   statutory Option shall be granted on the date when
                   such Outside Director first joins the Board of Direc-
                   tors and shall become exercisable ratably over a two-
                   year period.


                      (iii)  Upon the conclusion of each regular annual
                   meeting of the Company's stockholders, each Outside
                   Director who will continue serving as a member of the
                   Board of Directors thereafter shall receive a Non-
                   statutory Option covering 2,000 Shares (subject to
                   adjustment under Article 9), except that such Non-
                   statutory Option shall not be granted in the calendar
                   year in which the same Outside Director received the
                   Nonstatutory Option described in Paragraph (ii)
                   above.  Nonstatutory Options granted under this Para-
                   graph (iii) shall become exercisable ratably over a
                   two-year period.


                       (iv)  All Nonstatutory Options granted to an
                   Outside Director under this Subsection (b) shall also
                   become exercisable in full in the event of (A) the
                   termination of such Outside Director's service be-
                   cause of death, Total and Permanent Disability or
                   voluntary retirement at or after age 65 or (B) a
                   Change in Control with respect to the Company.


                        (v)  The Exercise Price under all Nonstatutory
                   Options granted to an Outside Director under this
                   Subsection (b) shall be equal to 100 percent of the
                   Fair Market Value of a Share on the date of grant,
                   payable in one of the forms described in Subsection
                   (a), (b), (c) or (d) of Section 8.








                                       -8-<PAGE>







                       (vi)  All Nonstatutory Options granted to an Out-
                   side Director under this Subsection (b) shall termi-
                   nate on the earliest of (A) the 10th anniversary of
                   the date of grant, (B) the date three months after
                   the termination of such Outside Director's service
                   for any reason other than death or Total and Perma-
                   nent Disability or (C) the date 12 months after the
                   termination of such Outside Director's service be-
                   cause of death or Total and Permanent Disability.


         The Committee may provide that the Nonstatutory Options that
         otherwise would be granted to an Outside Director under this
         Subsection (b) shall instead be granted to an affiliate of such
         Outside Director.  Such affiliate shall then be deemed to be an
         Outside Director for purposes of the Plan, provided that the
         service-related vesting and termination provisions pertaining
         to the Nonstatutory Options shall be applied with regard to the
         service of the Outside Director.


                   (c)  Ten-Percent Stockholders.  An Employee who owns
         more than 10 percent of the total combined voting power of all
         classes of outstanding stock of the Company or any of its Sub-
         sidiaries shall not be eligible for the grant of an ISO unless
         (i) the Exercise Price is at least 110 percent of the Fair
         Market Value of a Share on the date of grant and (ii) such ISO
         by its terms is not exercisable after the expiration of five
         years from the date of grant.


                   (d)  Attribution Rules.  For purposes of Subsection
         (c) above, in determining stock ownership, an Employee shall be
         deemed to own the stock owned, directly or indirectly, by or
         for such Employee's brothers, sisters, spouse, ancestors and
         lineal descendants.  Stock owned, directly or indirectly, by or
         for a corporation, partnership, estate or trust shall be deemed
         to be owned proportionately by or for its stockholders, part-
         ners or beneficiaries.  Stock with respect to which such Em-
         ployee holds an option shall not be counted.


                   (e)  Outstanding Stock.  For purposes of Subsection
         (c) above, "outstanding stock" shall include all stock actually
         issued and outstanding immediately after the grant.  "Outstand-
         ing stock" shall not include shares authorized for issuance
         under outstanding options held by the Employee or by any other
         person.






                                       -9-<PAGE>







         SECTION 5.  Stock Subject to Plan.


                   (a)  Basic Limitation.  Shares offered under the Plan
         shall be authorized but unissued Shares or treasury Shares.
         The aggregate number of Shares which may be issued under the
         Plan (upon exercise of Options or other rights to acquire
         Shares) shall not exceed 7,100,000 Shares, subject to adjust-
         ment pursuant to Section 9.  The number of Shares which are
         subject to Options or other rights outstanding at any time un-
         der the Plan shall not exceed the number of Shares which then
         remain available for issuance under the Plan.  The Company,
         during the term of the Plan, shall at all times reserve and
         keep available sufficient Shares to satisfy the requirements of
         the Plan.


                   (b)  Additional Shares.  In the event that any
         outstanding Option or other right for any reason expires or is
         canceled or otherwise terminated, the Shares allocable to the
         unexercised portion of such Option or other right shall again
         be available for the purposes of the Plan.  In the event that
         Shares issued under the Plan are reacquired by the Company pur-
         suant to a forfeiture provision, a right of repurchase or a
         right of first refusal, such Shares shall again be available
         for the purposes of the Plan.


         SECTION 6.  Terms and Conditions of Awards or Sales.


                   (a)  Stock Purchase Agreement.  Each award or sale of
         Shares under the Plan (other than upon exercise of an Option)
         shall be evidenced by a Stock Purchase Agreement between the
         Offeree and the Company.  Such award or sale shall be subject
         to all applicable terms and conditions of the Plan and may be
         subject to any other terms and conditions which are not incon-
         sistent with the Plan and which the Committee deems appropriate
         for inclusion in a Stock Purchase Agreement.  The provisions of
         the various Stock Purchase Agreements entered into under the
         Plan need not be identical.


                   (b)  Duration of Offers and Nontransferability of
         Rights.  Any right to acquire Shares under the Plan (other than
         an Option) shall automatically expire if not exercised by the
         Offeree within 30 days after the grant of such right was com-
         municated to the Offeree by the Committee.  Such right shall
         not be transferable and shall be exercisable only by the Of-
         feree to whom such right was granted.




                                       -10-<PAGE>







                   (c)  Purchase Price.  The Purchase Price of Shares to
         be offered under the Plan shall not be less than the par value
         of such Shares.  Subject to the preceding sentence, the Pur-
         chase Price shall be determined by the Committee at its sole
         discretion.  The Purchase Price shall be payable in a form des-
         cribed in Section 8.


                   (d)  Withholding Taxes.  As a condition to the award,
         sale or vesting of Shares, the Offeree shall make such arrange-
         ments as the Committee may require for the satisfaction of any
         federal, state, local or foreign withholding tax obligations
         that arise in connection with such Shares.  The Committee may
         permit the Offeree to satisfy all or part of his or her tax
         obligations related to such Shares by having the Company with-
         hold a portion of any Shares that otherwise would be issued to
         him or her or by surrendering any Shares that previously were
         acquired by him or her.  The Shares withheld or surrendered
         shall be valued at their Fair Market Value on the date when
         taxes otherwise would be withheld in cash.  The payment of
         taxes by assigning Shares to the Company, if permitted by the
         Committee, shall be subject to such restrictions as the Commi-
         ttee may impose, including any restrictions required by rules
         of the Securities and Exchange Commission.


                   (e)  Restrictions on Transfer of Shares.  Any Shares
         awarded or sold under the Plan shall be subject to such special
         forfeiture conditions, rights of repurchase, rights of first
         refusal and other transfer restrictions as the Committee may
         determine.  Such restrictions shall be set forth in the appli-
         cable Stock Purchase Agreement and shall apply in addition to
         any general restrictions that may apply to all holders of
         Shares.


         SECTION 7.  Terms and Conditions of Options.


                   (a)  Stock Option Agreement.  Each grant of an Option
         under the Plan shall be evidenced by a Stock Option Agreement
         between the Optionee and the Company.  Such Option shall be
         subject to all applicable terms and conditions of the Plan and
         may be subject to any other terms and conditions which are not
         inconsistent with the Plan and which the Committee deems appro-
         priate for inclusion in a Stock Option Agreement.  The pro-
         visions of the various Stock Option Agreements entered into
         under the Plan need not be identical.





                                       -11-<PAGE>







                   (b)  Number of Shares.  Each Stock Option Agreement
         shall specify the number of Shares that are subject to the
         Option and shall provide for the adjustment of such number in
         accordance with Section 9.  Options granted to any Optionee in
         a single calendar year shall in no event cover more than
         300,000 Shares, subject to adjustment in accordance with
         Section 9.  The Stock Option Agreement shall also specify
         whether the Option is an ISO or a Nonstatutory Option.


                   (c)  Exercise Price.  Each Stock Option Agreement
         shall specify the Exercise Price.  The Exercise Price of an ISO
         shall not be less than 100 percent of the Fair Market Value of
         a Share on the date of grant, except as otherwise provided in
         Section 4(c).  The Exercise Price of a Nonstatutory Option
         shall not be less than the par value of a Share.  Subject to
         the preceding two sentences, the Exercise Price under any
         Option shall be determined by the Committee at its sole discre-
         tion.  The Exercise Price shall be payable in a form described
         in Section 8.


                   (d)  Withholding Taxes.  As a condition to the exer-
         cise of an Option, the Optionee shall make such arrangements as
         the Committee may require for the satisfaction of any federal,
         state, local or foreign withholding tax obligations that arise
         in connection with such exercise.  The Optionee shall also make
         such arrangements as the Committee may require for the satis-
         faction of any federal, state, local or foreign withholding tax
         obligations that may arise in connection with the disposition
         of Shares acquired by exercising an Option.  The Committee may
         permit the Optionee to satisfy all or part of his or her tax
         obligations related to the Option by having the Company with-
         hold a portion of any Shares that otherwise would be issued to
         him or her or by surrendering any Shares that previously were
         acquired by him or her.  Such Shares shall be valued at their
         Fair Market Value on the date when taxes otherwise would be
         withheld in cash.  The payment of taxes by assigning Shares to
         the Company, if permitted by the Committee, shall be subject to
         such restrictions as the Committee may impose, including any
         restrictions required by rules of the Securities and Exchange
         Commission.


                   (e)  Exercisability.  Each Stock Option Agreement
         shall specify the date when all or any installment of the
         Option is to become exercisable.  The vesting of any Option
         shall be determined by the Committee at its sole discretion,
         except that each Option shall become exercisable in full in the
         event of the Optionee's death.  A Stock Option Agreement may 



                                       -12-<PAGE>







         also provide for accelerated exercisability in the event of the
         Optionee's Total and Permanent Disability or retirement, or
         other events.


                   (f)  Effect of Change in Control.  The Committee may
         determine, at the time of granting an Option or thereafter,
         that such Option shall become exercisable on an accelerated
         basis in the event that a Change in Control occurs with respect
         to the Company.  If the Committee finds that there is a reason-
         able possibility that, within the succeeding six months, a
         Change in Control will occur with respect to the Company, then
         the Committee may determine that all outstanding Options shall
         be exercisable on an accelerated basis.


                   (g)  Term.  Each Stock Option Agreement shall specify
         the term of the Option.  The term shall not exceed 10 years
         from the date of grant, except as otherwise provided in Section
         4(c).  Subject to the preceding sentence, the Committee at its
         sole discretion shall determine when an Option is to expire.


                   (h)  Nontransferability.  During an Optionee's life-
         time, such Optionee's Options shall be exercisable only by him
         or her and shall not be transferable.  In the event of an
         Optionee's death, such Optionee's Option(s) shall not be trans-
         ferable other than by will, by a beneficiary designation execu-
         ted by the Optionee and delivered to the Company or by the laws
         of descent and distribution.


                   (i)  No Rights as a Stockholder.  An Optionee, or a
         transferee of an Optionee, shall have no rights as a stock-
         holder with respect to any Shares covered by his or her Option
         until the date of the issuance of a stock certificate for such
         Shares.  No adjustments shall be made, except as provided in
         Section 9.


                   (j)  Modification, Extension and Renewal of Options.
         Within the limitations of the Plan, the Committee may modify,
         extend or renew outstanding Options or may accept the cancella-
         tion of outstanding Options (to the extent not previously exer-
         cised) in return for the grant of new Options at the same or a
         different price.  The foregoing notwithstanding, no modifica-
         tion of an Option shall, without the consent of the Optionee,
         impair such Optionee's rights or increase his or her obliga-
         tions under such Option.





                                       -13-<PAGE>







                   (k)  Restrictions on Transfer of Shares.  Any Shares
         issued upon exercise of an Option may be subject to such
         special forfeiture conditions, rights of repurchase, rights of
         first refusal and other transfer restrictions as the Committee
         may determine.  Such restrictions shall be set forth in the
         applicable Stock Option Agreement and shall apply in addition
         to any general restrictions that may apply to all holders of
         Shares.


         SECTION 8.  Payment for Shares.


                   (a)  General Rule.  The entire Purchase Price or
         Exercise Price of Shares issued under the Plan shall be payable
         in lawful money of the United States of America at the time
         when such Shares are purchased, except as follows:


                        (i)  In the case of Shares sold under the terms
                   of a Stock Purchase Agreement subject to the Plan,
                   payment shall be made only pursuant to the express
                   provisions of such Stock Purchase Agreement.  How-
                   ever, the Committee (at its sole discretion) may
                   specify in the Stock Purchase Agreement that payment
                   may be made in one or both of the forms described in
                   Subsections (e) and (f) below.


                       (ii)  In the case of an ISO granted under the
                   Plan, payment shall be made only pursuant to the ex-
                   press provisions of the applicable Stock Option
                   Agreement.  However, the Committee (at its sole dis-
                   cretion) may specify in the Stock Option Agreement
                   that payment may be made pursuant to Subsections (b),
                   (c), (d) or (f) below.


                      (iii)  In the case of a Nonstatutory Option
                   granted under the Plan, the Committee (at its sole
                   discretion) may accept payment pursuant to
                   Subsections (b), (c), (d) or (f) below.


                   (b)  Surrender of Stock.  To the extent that this
         Subsection (b) is applicable, payment may be made all or in
         part with Shares which have already been owned by the Optionee
         or his or her representative for more than 12 months and which
         are surrendered to the Company in good form for transfer.  Such 





                                       -14-<PAGE>







         Shares shall be valued at their Fair Market Value on the date
         when the new Shares are purchased under the Plan.


                   (c)  Exercise/Sale.  To the extent that this Subsec-
         tion (c) is applicable, payment may be made by the delivery (on
         a form prescribed by the Company) of an irrevocable direction
         to a securities broker approved by the Company to sell Shares
         and to deliver all or part of the sales proceeds to the Company
         in payment of all or part of the Exercise Price and any with-
         holding taxes.


                   (d)  Exercise/Pledge.  To the extent that this Sub-
         section (d) is applicable, payment may be made by the delivery
         (on a form prescribed by the Company) of an irrevocable direc-
         tion to pledge Shares to a securities broker or lender approved
         by the Company, as security for a loan, and to deliver all or
         part of the loan proceeds to the Company in payment of all or
         part of the Exercise Price and any withholding taxes.


                   (e)  Services Rendered.  To the extent that this Sub-
         section (e) is applicable, Shares may be awarded under the Plan
         in consideration of services rendered to the Company or a Sub-
         sidiary prior to the award.  If Shares are awarded without the
         payment of a Purchase Price in cash, the Committee shall make a
         determination (at the time of the award) of the value of the
         services rendered by the Offeree and the sufficiency of the
         consideration to meet the requirements of Section 6(c).


                   (f)  Promissory Note.  To the extent that this Sub-
         section (f) is applicable, a portion of the Purchase Price or
         Exercise Price, as the case may be, of Shares issued under the
         Plan may be payable by a full-recourse promissory note, pro-
         vided that (i) the par value of such Shares must be paid in
         lawful money of the United States of America at the time when
         such Shares are purchased, (ii) the Shares are security for
         payment of the principal amount of the promissory note and in-
         terest thereon and (iii) the interest rate payable under the
         terms of the promissory note shall be no less than the minimum
         rate (if any) required to avoid the imputation of additional
         interest under the Code.  Subject to the foregoing, the Commit-
         tee (at its sole discretion) shall specify the term, interest
         rate, amortization requirements (if any) and other provisions
         of such note.






                                       -15-<PAGE>







         SECTION 9.  Adjustment of Shares.


                   (a)  General.  In the event of a subdivision of the
         outstanding Stock, a declaration of a dividend payable in
         Shares, a declaration of a dividend payable in a form other
         than Shares in an amount that has a material effect on the
         value of Shares, a combination or consolidation of the out-
         standing Stock (by reclassification or otherwise) into a lesser
         number of Shares, a recapitalization, a spinoff or a similar
         occurrence, the Committee shall make appropriate adjustments in
         one or more of (i) the number of Shares available for future
         grants under Section 5, (ii) the number of Nonstatutory Options
         to be granted to Outside Directors under Section 4(b), (iii)
         the limit set forth in Section 7(b), (iv) the number of Shares
         covered by each outstanding Option or (v) the Exercise Price
         under each outstanding Option.


                   (b)  Reorganizations.  In the event that the Company
         is a party to a merger or other reorganization, outstanding
         Options shall be subject to the agreement of merger or reorga-
         nization.  Such agreement shall provide for the assumption of
         outstanding Options by the surviving corporation or its parent,
         for their continuation by the Company (if the Company is a sur-
         viving corporation), for payment of a cash settlement equal to
         the difference between the amount to be paid for one Share un-
         der such agreement and the Exercise Price, or for the accel-
         eration of their exercisability followed by the cancellation of
         Options not exercised, in all cases without the Optionees' con-
         sent.  Any cancellation shall not occur until after such accel-
         eration is effective and Optionees have been notified of such
         acceleration.  In the case of Options that have been outstan-
         ding for less than 12 months, a cancellation need not be pre-
         ceded by an acceleration.


                   (c)  Reservation of Rights.  Except as provided in
         this Section 9, an Optionee or Offeree shall have no rights by
         reason of any subdivision or consolidation of shares of stock
         of any class, the payment of any dividend or any other increase
         or decrease in the number of shares of stock of any class.  Any
         issue by the Company of shares of stock of any class, or secu-
         rities convertible into shares of stock of any class, shall not
         affect, and no adjustment by reason thereof shall be made with
         respect to, the number or Exercise Price of Shares subject to
         an Option.  The grant of an Option pursuant to the Plan shall
         not affect in any way the right or power of the Company to make
         adjustments, reclassifications, reorganizations or changes of
         its capital or business structure, to merge or consolidate or 




                                       -16-<PAGE>







         to dissolve, liquidate, sell or transfer all or any part of its
         business or assets.


         SECTION 10.  Securities Laws.


                   Shares shall not be issued under the Plan unless the
         issuance and delivery of such Shares complies with (or is ex-
         empt from) all applicable requirements of law, including (with-
         out limitation) the Securities Act of 1933, as amended, the
         rules and regulations promulgated thereunder, state securities
         laws and regulations, and the regulations of any stock exchange
         on which the Company's securities may then be listed.


         SECTION 11.  No Retention Rights.


                   Neither the Plan nor any Option shall be deemed to
         give any individual a right to remain an employee, consultant
         or director of the Company or a Subsidiary.  The Company and
         its Subsidiaries reserve the right to terminate the service of
         any employee, consultant or director at any time, with or with-
         out cause, subject to applicable laws, the Company's certifi-
         cate of incorporation and bylaws and a written employment
         agreement (if any).


         SECTION 12.  Duration and Amendments.


                   (a)  Term of the Plan.  The Plan, as set forth here-
         in, shall become effective on January 30, 1995, the date the
         Board of Directors amended and restated the Plan, subject to
         the approval of the Company's stockholders.  In the event the
         stockholders fail to approve the amendment to the Plan at the
         1995 annual meeting of stockholders, any Option grants or Stock
         awards made in excess of an aggregate of 6,100,000 Shares shall
         be null and void.  The Plan shall terminate automatically on
         January 29, 2005, and may be terminated on any earlier date
         pursuant to Subsection (b) below.


                   (b)  Right to Amend or Terminate the Plan.  The Board
         of Directors may amend, suspend or terminate the Plan at any
         time and for any reason, except that the provisions of Section
         4(b) relating to the amount, price and timing of grants to
         Outside Directors shall not be amended more than once in any 




                                       -17-<PAGE>







         six-month period.  An amendment of the Plan shall be subject to
         the approval of the Company's stockholders if it:


                        (i)  Increases the number of Shares available
                   for issuance under the Plan (except as provided in
                   Section 9);


                       (ii)  Changes the class of persons who are eli-
                   gible for the grant of ISO's; or


                      (iii)  To the extent required by Rule 16b-3 (or
                   any successor) under the Exchange Act, materially
                   increases the benefits accruing to participants under
                   the Plan or materially modifies the requirements as
                   to eligibility for participation in the Plan.


         Stockholder approval shall not be required for any other amend-
         ment of the Plan.


                   (c)  Effect of Amendment or Termination.  No Shares
         shall be issued or sold under the Plan after the termination
         thereof, except upon exercise of an Option granted prior to
         such termination.  The termination of the Plan, or any amend-
         ment thereof, shall not affect any Share previously issued or
         any Option previously granted under the Plan.


         SECTION 13.  Execution.


                   To record the amendment and restatement of the Plan
         by the Board of Directors on January 30, 1995, the Company has
         caused its authorized officer to execute the same.


                                         PYXIS CORPORATION



                                         By:/s/ Ronald R. Taylor        
                                            ____________________________
                                                Chief Executive Officer







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