IMMUNOMEDICS INC
SC 13D/A, 1999-05-19
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13D

                  Under the Securities and Exchange Act of 1934
                                (Amendment No. 5)


                               IMMUNOMEDICS, INC.
                                (Name of Issuer)

                          Common Stock, $.01 Par Value
                         (Title of Class of Securities)

                                   452907 10 8
                                 (CUSIP Number)

                              Howard M. Cohen, Esq.
                  Warshaw Burstein Cohen Schlesinger & Kuh, LLP
                                555 Fifth Avenue
                            New York, New York 10017
                                 (212) 984-7700
                       (Name, Address and Telephone Number
                         of Person Authorized to Receive
                           Notices and Communications)

                                   May 3, 1999
             (Date of Event which Requires Filing of this Statement)



If the filing person has previously  filed a statement on Schedule 13G to report
the  acquisition  which is the subject of this  Schedule 13D, and is filing this
schedule because of Rule 13d- 1(b)(3) or (4), check the following box [ ].

Check the following box if a fee is being paid with statement [ ].


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<PAGE>


         CUSIP No.   452907 10 8
         _______________________________________________________________________
(a)      Name of Reporting Persons S.S. or I.R.S.
         Identification Nos. of Above Person
                                                             David M. Goldenberg
         _______________________________________________________________________
(b)      Check the Appropriate Box if a Member of a Group
         (See Instructions)
                                                                    (a)      [X]
                                                                    (b)      [ ]
         _______________________________________________________________________
(c)      SEC Use Only

         _______________________________________________________________________
(d)      Source of Funds (See Instructions)

                                                                             N/A
         _______________________________________________________________________
(e)      Check if Disclosure of Legal Proceedings is
         Required Pursuant to Items 2(d) or 2(e)
                                                                             [ ]
         _______________________________________________________________________
(f)      Citizenship or Place of Organization
                                                                   United States
         _______________________________________________________________________

         Number of Shares           (g)     Sole Voting Power          7,902,833
         Beneficially               ____________________________________________
         Owned by Each              (h)     Shared Voting Power        4,032,185
         Reporting                  ____________________________________________
         Person With                (i)     Sole Dispositive Power     7,902,833
                                    ____________________________________________
                                    (j)     Shared Dispositive Power   2,813,016
         _______________________________________________________________________
(k)      Aggregate Amount Beneficially Owned by Each                  12,581,591
         Reporting Person
         _______________________________________________________________________
(l)      Check if the Aggregate Amount in Row (11) Excludes
         Certain Shares (See Instructions)                                   [ ]
         _______________________________________________________________________
(m)      Percent of Class Represented by Amount in Row (11)                32.9%
         _______________________________________________________________________
(n)      Type of Reporting Person (See Instructions)                          IN
         _______________________________________________________________________

                                        2

<PAGE>



         CUSIP No.   452907 10 8
         _______________________________________________________________________
(a)      Name of Reporting Persons S.S. or I.R.S.
         Identification Nos. of Above Person
                                                               Deborah S. Orlove
         _______________________________________________________________________
(b)      Check the Appropriate Box if a Member of a Group
         (See Instructions)                                         (a)      [X]
                                                                    (b)      [ ]
         _______________________________________________________________________
(c)      SEC Use Only

         _______________________________________________________________________
(d)      Source of Funds (See Instructions)                                  N/A

         _______________________________________________________________________
(e)      Check if Disclosure of Legal Proceedings is
         Required Pursuant to Items 2(d) or 2(e)                             [ ]
         _______________________________________________________________________
(f)      Citizenship or Place of Organization                      United States
         _______________________________________________________________________

         Number of Shares           (g)     Sole Voting Power                  0
         Beneficially               ____________________________________________
         Owned by Each              (h)     Shared Voting Power        2,350,728
         Reporting                  ____________________________________________
         Person With                (i)     Sole Dispositive Power             0
                                    ____________________________________________
                                    (j)     Shared Dispositive Power   2,350,728
         _______________________________________________________________________
(k)      Aggregate Amount Beneficially Owned by Each
         Reporting Person                                              2,350,728
         _______________________________________________________________________
(l)      Check if the Aggregate Amount in Row (11) Excludes
         Certain Shares (See Instructions)                                   [ ]
         _______________________________________________________________________
(m)      Percent of Class Represented by Amount in Row (11)                 6.2%
         _______________________________________________________________________
(n)      Type of Reporting Person (See Instructions)                          IN
         _______________________________________________________________________

                                        3

<PAGE>



         CUSIP No.   452907 10 8
         _______________________________________________________________________
(a)      Name of Reporting Persons S.S. or I.R.S.
         Identification Nos. of Above Person
                                                               Eva J. Goldenberg
         _______________________________________________________________________
(b)      Check the Appropriate Box if a Member of a Group
         (See Instructions)                                         (a)      [X]
                                                                    (b)      [ ]
         _______________________________________________________________________
(c)      SEC Use Only

         _______________________________________________________________________
(d)      Source of Funds (See Instructions)                                  N/A

         _______________________________________________________________________
(e)      Check if Disclosure of Legal Proceedings is
         Required Pursuant to Items 2(d) or 2(e)                             [ ]
         _______________________________________________________________________
(f)      Citizenship or Place of Organization                      United States
         _______________________________________________________________________

         Number of Shares           (g)     Sole Voting Power                  0
         Beneficially               ____________________________________________
         Owned by Each              (h)     Shared Voting Power        2,350,728
         Reporting                  ____________________________________________
         Person With                (i)     Sole Dispositive Power             0
                                    ____________________________________________
                                    (j)     Shared Dispositive Power   2,350,728
         _______________________________________________________________________
(k)      Aggregate Amount Beneficially Owned by Each
         Reporting Person                                              2,350,728
         _______________________________________________________________________
(l)      Check if the Aggregate Amount in Row (11) Excludes
         Certain Shares (See Instructions)                                   [ ]
         _______________________________________________________________________
(m)      Percent of Class Represented by Amount in Row (11)                 6.2%
         _______________________________________________________________________
(n)      Type of Reporting Person (See Instructions)                          IN
         _______________________________________________________________________


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<PAGE>



                  This  Amendment  No. 5 amends the Schedule 13D filed on behalf
of David M.  Goldenberg,  Deborah S. Orlove and Eva J.  Goldenberg,  and certain
other persons on February 15, 1985, as amended (the "Statement"). This Amendment
reflects, among other things: (i) the decrease in the number of shares of common
stock owned by David M. Goldenberg as a result of a certain involuntary sales of
common stock and (ii) the removal,  as joint filers,  of certain of his children
and an entity  under  his  control  as they own less than 5% of the  outstanding
Common Stock and are not  required to file a Schedule 13D (David M.  Goldenberg,
Deborah S. Orlove and Eva J.  Goldenberg,  are  collectively  referred to as the
"Reporting  Persons").  Capitalized  terms used herein but not otherwise defined
herein shall have the meanings assigned to such terms in the Statement.


Item 3.           Purpose of Transaction.

                  During the period April 20, 1999 through May 7, 1999,  700,000
shares  of  common  stock  owned  directly  by  Dr.  David  M.  Goldenberg  were
involuntarily  sold by a pledgee of the shares. The pledgee held these shares as
collateral  pursuant  to an alleged  pledge  arrangement  and sold the shares in
partial  repayment of the loan.  Dr.  Goldenberg did not approve the sale of the
shares and disputes the authority of the pledgee to sell the shares without such
approval.

Item 4.           Interest in Securities of the Issuer.

                  As  of  May  14, 1999,  David M. Goldenberg beneficially owned
12,581,591  shares  of  Common  Stock,  comprising  approximately  32.9%  of the
outstanding Common Stock. Dr. Goldenberg's ownership reported above consists of:

                  (a)      7,035,161  shares  of  Common Stock owned directly by
                           Dr. Goldenberg;

                  (b)      2,633,016  shares of Common Stock owned by certain of
                           Dr.  Goldenberg's  children  as to  which  he  shares
                           voting and  dispositive  power with such  children by
                           reason of powers of attorney granted to him by them;

                  (c)      1,219,169  shares of Common  Stock owned by Hildegard
                           Gruenbaum,  as to which Dr.  Goldenberg shares voting
                           power with  Hildegard  Gruenbaum by reason of a proxy
                           granted to him by her;

                  (d)      867,672  shares of Common  Stock owned by a trust for
                           the benefit of one of Dr. Goldenberg's children as to
                           which he serves as the trustee;

                  (e)      307,692 shares of Common Stock, owned by the David M.
                           Goldenberg 1989 Trust (the "DMG Trust"),  as to which
                           Dr.  Goldenberg  has the  right  to  receive  certain
                           income generated by such trust;


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<PAGE>



                  (f)      113,831   shares  of  Common   Stock   owned  by  Dr.
                           Goldenberg's current wife, consisting of 5,131 shares
                           owned  directly by her and  108,750  shares of Common
                           Stock  which  she  has  the  right  to  acquire  upon
                           exercise of presently exercisable options;

                  (g)      225,000  shares of Common Stock which Dr.  Goldenberg
                           has the right to acquire  upon  exercise of presently
                           exercisable options, and

                  (h)      200,000  shares  of  Common  Stock  owned by  Escalon
                           Corp.,  of which Dr.  Goldenberg  is the sole officer
                           and  director,  and as a result has shared voting and
                           dispositive power,

                  Dr. Goldenberg disclaims beneficial  ownership with respect to
all shares owned by his children, his wife or Ms. Gruenbaum.

                  As  of  May  14,  1999  Deborah S. Orlove (formerly Deborah S.
Goldenberg)  beneficially  owned  2,324,784  shares of Common Stock,  comprising
approximately  6.5% of the  outstanding  Common Stock.  Ms.  Orlove's  ownership
reported above consists of:

                  (a)      877,672  shares of Common Stock owned directly by Ms.
                           Orlove,  as to which Ms.  Orlove  shares  voting  and
                           dispositive  power with Dr. Goldenberg as a result of
                           the power of attorney granted by her to him;

                  (b)      857,672  shares of Common  Stock held by the Denis C.
                           Goldenberg 1993 Trust (the "DCG Trust"), of which Ms.
                           Orlove is a co-trustee  with Eva  Goldenberg and as a
                           result shares voting and dispositive power with her;

                  (c)      307,692  shares of Common Stock held by the Hildegard
                           Goldenberg 1989 Trust (the "HG Trust"),  of which Ms.
                           Orlove is a co-trustee  with Eva  Goldenberg and as a
                           result shares voting and dispositive  power with her;
                           and

                  (d)      307,692 shares of Common Stock held by the DMG Trust,
                           of  which  Ms.  Orlove  is  a  co-trustee   with  Eva
                           Goldenberg   and  as  a  result   shares  voting  and
                           dispositive power with her.

                  Ms. Orlove  disclaims beneficial ownership of all shares owned
by the DCG Trust, the HG Trust and the DMG Trust.

                  As  of  May 14, 1999, Eva  J.  Goldenberg  beneficially  owned
2,324,784  shares  of  Common  Stock,  comprising   approximately  6.5%  of  the
outstanding Common Stock. Ms. Goldenberg ownership reported above consists of:


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<PAGE>



                  (a)      877,672  shares of Common Stock owned directly by Ms.
                           Goldenberg,  as to which Ms. Goldenberg shares voting
                           and dispositive power with Dr. Goldenberg as a result
                           of the power of attorney granted by her to him;

                  (b)      857,672  shares of Common  Stock held by the Denis C.
                           Goldenberg 1993 Trust (the "DCG Trust"), of which Ms.
                           Goldenberg is a co-trustee with Eva Goldenberg and as
                           a result  shares  voting and  dispositive  power with
                           her;

                  (c)      307,692  shares of Common Stock held by the Hildegard
                           Goldenberg 1989 Trust (the "HG Trust"),  of which Ms.
                           Goldenberg is a co-trustee with Deborah Orlove and as
                           a result  shares  voting and  dispositive  power with
                           her; and

                  (d)      307,692 shares of Common Stock held by the DMG Trust,
                           of which Ms.  Goldenberg is a co-trustee with Deborah
                           Orlove and as a result shares voting and  dispositive
                           power with her.

                  Ms.  Goldenberg  disclaims  beneficial ownership of all shares
owned by the DCG Trust, the HG Trust and the DMG Trust.

                  Except as set forth above,  the Reporting  Persons did not own
any options,  warrants or other rights to acquire shares. Except as set forth on
Annex A, the  Reporting  Persons did not effect any  transactions  in the Common
Stock during the past 60 days.

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<PAGE>



                                   Signature.

                  After  reasonable  inquiry and to the best of my knowledge and
belief,  I certify  that the  information  set forth in this  Statement is true,
complete and correct.


Dated: May 14, 1999                                      /s/ David M. Goldenberg
                                                         _______________________
                                                         David M. Goldenberg

Dated: May 14, 1999                                      /s/ Deborah S. Orlove
                                                         _______________________
                                                         Deborah S. Orlove

Dated: May 14, 1999                                      /s/ Eva J. Goldenberg
                                                         _______________________
                                                         Eva J. Goldenberg




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<PAGE>



                                                                       EXHIBIT 1

                                AGREEMENT TO FILE
                                A JOINT STATEMENT

                  By their  signatures,  the  undersigned  agree to file a joint
Schedule 13D and understand that such statement is filed by or on behalf of each
of them.



Dated: May 14, 1999                                      /s/ David M. Goldenberg
                                                         _______________________
                                                         David M. Goldenberg

Dated: May 14, 1999                                      /s/ Deborah S. Orlove
                                                         _______________________
                                                         Deborah S. Orlove

Dated: May 14, 1999                                      /s/ Eva J. Goldenberg
                                                         _______________________
                                                         Eva J. Goldenberg


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<PAGE>


                                                                         Annex A

                  During the 60-day  period  ending May 14, 1999,  the following
sales of Common Stock owned by David M.  Goldenberg were effected by the pledgee
referenced in Item 4.


      Date of                              Number of              Sales Price
     Transaction                          Shares Sold              per Share
________________________________________________________________________________
          4/20/99                            15,000                  $2.125
          4/21/99                            15,000                  $2.063
          4/23/99                            15,000                  $2.031
          4/27/99                            10,000                  $1.500
          4/27/99                           100,000                  $1.563
          4/28/99                           100,000                  $1.375
          4/29/99                            50,000                  $1.500
          4/29/99                            25,000                  $1.625
          4/29/99                            25,000                  $1.563
          5/3/99                             75,000                  $1.771
          5/5/99                             25,000                  $1.625
          5/6/99                             30,000                  $1.563
          5/7/99                            215,000                  $1.125


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