MEDCO RESEARCH INC
8-A12B/A, 1998-04-27
PHARMACEUTICAL PREPARATIONS
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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM 8-A/A

                                 AMENDMENT NO. 1

                       AMENDMENT TO APPLICATION OR REPORT

                FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES
                    PURSUANT TO SECTION 12 (b) or (g) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

                              MEDCO RESEARCH, INC.
             (Exact name of registrant as specified in its charter)


         This Amendment contains a new Exhibit B, "Summary of Rights to Purchase
Common  Shares," to  Registrant's  Stockholders  Rights Plan,  which as filed as
Exhibit 4.1 to  Registrant's  Form 8-A  Registration  Statement  registering the
Rights under the  Securities  Exchange Act of 1934, as amended.  The Exhibit was
revised to describe additional provisions of the Plan.



                                     MEDCO RESEARCH, INC.
                                         (Registrant)


                                     By: /s/ Glenn C. Andrews 
                                        ---------------------------------------
                                        Glenn C. Andrews, Vice President,
                                        Finance and Administration and
                                        Chief Financial Officer





                            EXHIBIT B TO EXHIBIT 4.1


                              MEDCO RESEARCH, INC.
                            STOCKHOLDERS RIGHTS PLAN

                          SUMMARY OF RIGHTS TO PURCHASE
                                  COMMON SHARES

         On April 2, 1998, the Directors of Medco Research, Inc. (the "Company")
declared a dividend  distribution of one right (a "Right") for each  outstanding
Common  Share,  without par value (the "Common  Shares"),  of the  Company.  The
distribution  is payable on April 15, 1998 to the  shareholders  of record as of
the  close of  business  on April 14,  1998  (the  "Record  Date").  Each  Right
initially  entitles the registered  holder to purchase from the Company one-half
of one Common Share at a price of $92.00 per whole share,  subject to adjustment
(the "Purchase Price"). The description and terms of the Rights are set forth in
a Rights Agreement dated as of April 14, 1998 (the "Rights  Agreement")  between
the Company and American Stock  Transfer & Trust  Company,  as Rights Agent (the
"Rights Agent").

         Until  the  earlier  of  (i)  ten  Business  Days  following  a  public
announcement  that a person or group of  affiliated  or  associated  persons (an
"Acquiring Person") has acquired,  or obtained the right to acquire,  beneficial
ownership of 20% or more of the outstanding  Common Shares, or (ii) ten Business
Days following the  commencement  of a tender offer or exchange offer for 20% or
more of such outstanding  Common Shares (in each case without the prior approval
of the Board of Directors) (the earlier of such dates being  hereinafter  called
the "Distribution  Date"), the Rights will be evidenced,  with respect to any of
the Common Share certificates  outstanding as of the Record Date, by such Common
Share  certificate with a copy of this Summary of Rights attached  thereto.  The
Rights Agreement  provides that, until the Distribution Date, the Rights will be
transferred with and only with the Common Shares.  Until the  Distribution  Date
(or  earlier  redemption  or  expiration  of  the  Rights),   new  Common  Share
certificates  issued  after the Record  Date upon  transfer  or new  issuance of
Common  Shares will  contain a notation  incorporating  the Rights  Agreement by
reference.  Until the Distribution Date (or earlier  redemption or expiration of
the Rights),  the surrender for transfer of any  certificates  for Common Shares
outstanding as of the Record Date, even without a copy of this Summary of Rights
attached  thereto,  will also  constitute the transfer of the Rights  associated
with the Common Shares  represented by such certificate.  As soon as practicable
following  the  Distribution  Date (as  defined  above),  separate  certificates
evidencing  the Rights (the "Right  Certificates")  will be mailed to holders of
record of the Common Shares as of the close of business on the Distribution Date
and such separate Right Certificates alone will evidence the Rights.

         The Rights are not exercisable until the Distribution  Date. The Rights
will  expire on April 15,  2008,  unless  earlier  redeemed  by the  Company  as
described below.

         The Purchase  Price  payable,  and the number of Common Shares or other
securities  or  property  issuable,  upon  exercise of the Rights are subject to
adjustment  from time to time to  prevent  dilution  (i) in the event of a stock
dividend on, or a subdivision,  combination or  reclassification  of, the Common
Shares,  (ii) upon the grant to holders of the Common Shares of certain  rights,
options or warrants to subscribe for Common Shares or convertible  securities at
less than the  current  market  price of the  Common  Shares,  or (iii) upon the
distribution to holders of the Common Shares of evidences of indebtedness,  cash
(excluding  regular  periodic cash  dividends at a rate not in excess of 125% of
the rate of the last cash dividend  theretofore paid), assets, stock (other than
dividends  payable  in Common  Shares)  or of  subscription  rights,  options or
warrants (other than those referred to above).

         In the event that an Acquiring  Person  merges into the Company and the
Company's  Common  Shares are not changed or  exchanged  or a person or group of
affiliated or associated  persons become the beneficial  owner of 20% or more of
the Company's Common Shares,  proper provision shall be made so that each holder
of a  Right,  other  than  Rights  that  are or were  beneficially  owned by the
Acquiring  Person  after the date upon which the  Acquiring  Person  became such
(which  Rights  will  thereafter  be void),  will  thereafter  have the right to
receive upon exercise  thereof at the then current Purchase Price that number of
Common Shares having a market value of two times the Purchase  Price (or,  under
certain circumstances,  an amount of cash or other property or securities having
a value equal to the Purchase Price).  In the event that the Company is acquired
by an Acquiring Person in a merger or other business combination  transaction or
50% or more of its  assets  or  earning  power are sold to an  Acquiring  Person
(other than in a  transaction  approved by the Company's  shareholders),  proper
provision  shall be made so that each holder of a Right,  other than Rights that
are or were beneficially owned by the Acquiring Person after the date upon which
the Acquiring  Person became such (which Rights will thereafter be void),  shall
thereafter  have the right to  receive,  upon the  exercise  thereof at the then
current  Purchase  Price,  that  number  of Common  Shares  (or,  under  certain
circumstances,  an  economically  equivalent  security  or  securities)  of  the
surviving,  resulting or acquiring  person which at the time of such transaction
would have a market value of two times the  Purchase  Price (or,  under  certain
circumstances,  an amount of cash  equal to the  Purchase  Price).  The Board of
Directors of the Company may, at its option,  at any time after the later of the
Distribution Date and the first occurrence of a Triggering  Event,  exchange all
or part of the  then-outstanding and exercisable Rights (other than Rights owned
by an  Acquiring  Person) for Common  Shares at an exchange  ratio of one Common
Share per Right.

         With certain  exceptions,  no adjustment in the Purchase  Price will be
required until  cumulative  adjustments  require an adjustment of at least 1% in
such Purchase Price.  No fractional  shares will be issued (other than fractions
which may, at the election of the Company, be evidenced by depositary receipts),
and in lieu  thereof a payment in cash will be made based on the market price of
the Common Shares on the last trading day prior to the date of exercise.

         The Company may redeem the Rights in whole, but not in part, at a price
of $0.01 per Right  (the  "Redemption  Price") at any time prior to the later of
(i) the Distribution Date and (ii) a public  announcement that a person or group
of affiliated or associated persons has acquired beneficial  ownership of 20% or
more of the  outstanding  Common Shares (or such later date as the Directors may
specify) and, under certain circumstances, upon a merger or consolidation of the
Company  with or into a  corporation  which is not an Acquiring  Person.  At the
election of the Company,  the  Redemption  Price may be payable in cash,  Common
Shares,  or  such  other   consideration  as  the  Company  deems   appropriate.
Immediately  upon  the  action  of  the  Directors  of the  Company  authorizing
redemption  of the Rights,  the right to exercise the Rights will  terminate and
the only right of the holders of Rights will be to receive the Redemption Price.
The  Company  will give  notice of such  redemption  to the  holders of the then
outstanding  Rights by  mailing  such  notice to all such  holders at their last
addresses as they appear on the Registry Books of the Rights Agent.

         Until a Right is exercised,  the holder thereof,  as such, will have no
rights as a shareholder of the Company, including, without limitation, the right
to vote or to receive dividends.

         Prior to the Rights becoming  exercisable,  without the approval of any
holders of Rights,  the Rights  Agreement may be amended or  supplemented by the
Company and the Rights Agent in any manner except for an amendment or supplement
which would change the Redemption Price, reduce the Purchase Price or change the
number  of  Common  Shares  for  which a Right  is then  exercisable,  provided,
however,  that  between  April  15,  2001 and  September  30,  2001 the Board of
Directors shall review the other provisions of the Rights  Agreement,  including
without  limitation the Final Expiration Date to determine what  amendments,  if
any, are  necessary or  appropriate  to  effectuate  better the purposes of such
Agreement.  After the Distribution  Date, the Rights Agreement may be so amended
or  supplemented  to  cure  ambiguity,   correct  or  supplement   defective  or
inconsistent  provisions  or  otherwise  as the Company and the Rights Agent may
deem necessary or desirable and shall not adversely  affect the interests of the
Rights holders.

A copy of the Rights  Agreement is being filed with the  Securities and Exchange
Commission as an Exhibit to a Registration  Statement on Form 8-A. A copy of the
Rights  Agreement  is available  free of charge from the  Company.  This summary
description  of the Rights does not purport to be complete  and is  qualified in
its entirety by reference to the Rights Agreement,  which is hereby incorporated
herein by reference.



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