MICROFLUIDICS INTERNATIONAL CORP
10-K, 1996-04-01
LABORATORY APPARATUS & FURNITURE
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<PAGE>
 
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                                   FORM 10-K

                                  -------------

                ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF
                      THE SECURITIES EXCHANGE ACT OF 1934

                  FOR THE FISCAL YEAR ENDED DECEMBER 31, 1995

                                  -------------

                    MICROFLUIDICS INTERNATIONAL CORPORATION
             (EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)


               DELAWARE                                04-2793022
               --------                                ----------
    (State or other jurisdiction of       (I.R.S. Employer Identification No.)
     incorporation or organization)

     30 OSSIPEE ROAD, P.0. BOX 9101
         NEWTON, MASSACHUSETTS                         02164-9101
     ------------------------------                    ----------
(Address of principal executive offices)               (Zip Code)

                        COMMISSION FILE NUMBER:  0-11625

       REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE: (617) 969-5452
       SECURITIES REGISTERED PURSUANT TO SECTION 12(b) OF THE ACT:  NONE
          SECURITIES REGISTERED PURSUANT TO SECTION 12(g) OF THE ACT:
                          COMMON STOCK, $.01 PAR VALUE

Indicate by check mark whether the registrant:  (1) has filed all reports
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of
1934 during the preceding 12 months (or for such shorter period that the
registrant was required to file such reports), and (2) has been subject to the
filing requirements for the past 90 days.
Yes  X    No
    ---      ---
 
Indicate by check mark if disclosure of delinquent filers pursuant to Item 405
of Regulation S-K is not contained herein, and will not be contained, to the
best of registrant's knowledge, in definitive proxy or information statements
incorporated by reference in Part III of this Form 10-K or any amendment to this
Form 10-K. [_]

The aggregate market value of Common Stock held by non-affiliates of the
registrant as of March 26, 1996 was $8,564,822.

The number of shares outstanding of the registrant's Common Stock as of March
26, 1996 was 5,075,450 shares.

                      DOCUMENTS INCORPORATED BY REFERENCE

The registrant intends to file a definitive proxy statement pursuant to
Regulation 14A within 120 days of the end of the fiscal year ended December 31,
1995.  Portions of such proxy statement are incorporated by reference into Part
III of this report.
<PAGE>
 
ITEM 1.  BUSINESS:

COMPANY OVERVIEW:
- ---------------- 

     Microfluidics International Corporation ("Microfluidics" or the "Company"),
through its wholly-owned subsidiaries, Microfluidics Corporation ("MFC") and
MediControl Corporation ("MediControl"), which is currently inactive,
specializes in producing and marketing proprietary Microfluidizer/(R)/ devices
used for the creation of micro droplets and dispersions in liquid streams for
very fine mixing and blending applications. Microfluidizer devices have wide-
spread applications in the chemical processing, pharmaceutical, biotechnology,
cosmetics and food processing industries.

     Microfluidizer equipment is used to formulate emulsions, dispersions and
liposomes, and is used in cell rupture. Emulsions are intimate mixtures of oil
and water (or other normally immiscible components). They are found in a broad
variety of common products, including processed foods, medicines and
photographic films. Dispersions are mixtures of fine solids suspended in liquids
and are often employed in products such as inks, pigments and coatings. The
Company believes that the processing technique of the Microfluidizer equipment
enhances the stability and consistency of emulsions and dispersions due to the
equipment's unique ability to consistently produce uniform micron scale
particles in many applications. Liposomes are biodegradable, cell-like
structures used to entrap medications or nutrients, and are typically used in
cosmetics or pharmaceutical products. In addition, Microfluidizer equipment may
be used in biotechnology applications to harvest, through cell rupture, the
desired product contents of plant and animal cells.

     The Company was incorporated in Delaware in 1983. The Company, formerly
named Biotechnology Development Corporation, changed its name effective June 8,
1993 to Microfluidics International Corporation. Its principal executive offices
are located at 30 Ossipee Road, in Newton, Massachusetts, and its telephone
number is (617) 969-5452.

THE TECHNOLOGY:
- -------------- 

     The Company's Microfluidizer devices are based on a patent and related
technology that was licensed by MFC from Arthur D. Little & Co. in 1983 and
subsequently purchased by MFC in 1985.  The Company holds two United States
patents related to the apparatus and process used to intimately mix liquids and
disperse particulate solids in microemulsions.

     The Company's Microfluidizer is used in the processing industries to mix
materials that are normally very difficult to mix. The Microfluidizer allows
manufacturers in such industries as chemicals, pharmaceuticals, cosmetics,
biotechnology and food processing, to produce higher quality products with
better characteristics on a more consistent basis than with other blending and
mixing techniques.

     In the Microfluidizer, two or more ingredients are pumped into the device
under high pressure. The fluid streams are then injected at very high speeds
into the proprietary interaction chamber where the particles collide and
interact. This collision of fluids causes the thorough mixing and integration of
the component ingredients. The result is a uniform, consistent, lump-free
product which can be anything from paint to a vaccine. The process can also be
used in biotechnology cell-rupture applications. The precision with which the
Microfluidizer can be used to break up materials allows the encapsulating cell
wall to be ruptured without damage to or contamination of the cell contents. The
advantage of Microfluidics' equipment is its ability to: (i) reduce the particle
size of ingredients to minute levels using extremely high pressures (up to
40,000 pounds per square inch ("psi"); and (ii) precisely control the process
so all component ingredients are uniformly affected by interaction.

     The Company believes its patented Microfluidizer device, with its unique
ability to consistently produce micron and sub-micron-size particles, allows
users to manufacture new and improved formulations with enhanced

                                       2
<PAGE>
 
product stability and formulation consistency.  The Company's technology is
distinguished by its ability to provide uniform treatment of all elements of a
formulation.  A fixed geometry mixing chamber and consistent pressure pump
technology result in high intensity forces of shear (flow), impact and
cavitation (vapor bubble implosion) in the interaction chamber.  The process
stream can operate at near constant pressures of up to 40,000 psi.  In contrast,
the Company believes that other mixing technologies are limited by non-uniform
pressure and variable geometry processes, which generally have much lower
practical operating pressures and result in less uniform formulations that are
inferior to those produced with the Microfluidizer.

     The Company believes that its proprietary interaction chamber
differentiates its equipment from the equipment of its competitors. In the
Company's equipment, all processed material must flow through fixed channels
under constant pressure to a confined liquid collision zone. The resulting
shear, impact and cavitation forces uniformly affect all materials in the zone,
reducing the size of droplets or particles in the material flow to a uniform
micron-size scale. Smaller and more uniform particles result in increased
surface area that can substantially improve the compatibility of formulation
ingredients, allowing a much higher level of intimate mixing and homogeneity.

     Among the many benefits provided by the Microfluidizer process for various
industries are:

     *  extended shelf life
     *  enhanced flavor and texture
     *  consistent color and fragrance
     *  improved delivery of drugs and cosmetics
     *  elimination of additives and solvents
     *  more uniform product appearance
     *  more effective (higher yield) cell rupture

     In February 1995, the Company introduced the Diamond Interaction Chamber as
a product enhancement to the Microfluidizer. This chamber uses diamond surfaces
in the high wear regions of the chamber, rather than the Company's proprietary
ceramic materials. While the standard ceramic interaction chamber is generally
acceptable for most applications, the Diamond Interaction Chamber was designed
to reduce wear in the chamber from applications that introduce abrasive
materials into the process stream, such as metal oxides, and cause significant
wear to areas of high energy transfer. Proprietary material preparation,
machining and assembly methodologies for the Company's Diamond Interaction
Chamber were developed during 1993 and 1994.

     The Company believes that the equipment of its competitors generally
incorporate mechanical components in the mixing valves that move continually
during processing, allowing variable size particles to pass through and
resulting in non-uniform, inconsistent products.  In contrast, the Company's
equipment contains no in-line moving parts in the high energy mixing zone.  In
addition, while the Company believes that competing equipment frequently needs
to repeat a mixing process cycle (pass), Microfluidics' equipment can achieve
results that are similar to its competitor's results with fewer mixing
processes.  An additional advantage of the Microfluidizer equipment is that it
can be scaled up to larger, higher volume product requirements in a reliable
manner.

COMMERCIAL APPLICATIONS:
- ----------------------- 

     The Microfluidizer equipment can be used to mix and formulate emulsions,
dispersions and liposomes, and for cell rupture.

     Emulsions are homogenous mixtures of oil and water components (or other
normally immiscible components), which, if mixed properly, do not readily
separate. Emulsions make up many products, such as processed foods, medicines,
photographic films, hydraulic fluids and polymers. The Company believes that,
generally, an emulsion processed with a Microfluidizer unit will exhibit
improved stability and require reduced concentrations of costly emulsifying
agents that are needed to enhance product stability.

                                       3
<PAGE>
 
      Dispersions are mixtures of fine solids suspended in liquid so that
the two do not separate readily after processing.  Similar to emulsions,
dispersions are used in a variety of consumer and industrial products, including
pigments for paints and inks, iron oxide for magnetic tapes and mascara,
phosphorescent coatings for TV screens and fluorescent lamps, barium titanate
for capacitors, toners and inks, aluminum hydroxide (antacid) and ketchup.

      Liposomes are biodegradable cell-like structures, formed from materials
such as cholesterol and lecithin, that can be used to entrap medications or
nutrients. Pharmaceutical and cosmetic manufacturers use liposomes as a delivery
system to target active ingredients for specific anatomical sites and to prolong
their efficacy. To date, liposomes have been used commercially primarily in the
area of medical diagnostic agents and cosmetics. Applications include the
encapsulation of dye to be used as a marker in medical diagnostic tests and the
encapsulation of ingredients for deeper skin penetration, as well as
pharmaceutical, food and specialized agricultural applications.

      In the biotechnology industry, Microfluidizer equipment is currently used
to harvest, by cell rupture, the contents of plant or animal cells. The
precision with which the Microfluidizer can be used to break up materials allows
the encapsulating cell wall to be ruptured without damage to or contamination of
the cell contents. As a result, the Microfluidizer equipment minimizes the
amount and presence of cell wall debris, thus resulting in maximum yields.

      With the introduction of the Diamond Interaction Chamber, the Company has
targeted the markets for processing abrasive materials by wet milling and wet
grinding, which cause the deagglomeration and dispersion of these materials into
slurries.

      The Company continually seeks to expand the applications for which the
Microfluidizer technology can be used.  The Company is exploring other
applications for the Microfluidizer technology in research and licensing
arrangements with Worcester Polytechnic Institute ("WPI") and Catalytica, Inc.
("Catalytica").  See "Research and Development".

THE PRODUCTS:
- ------------ 

      Microfluidics currently manufactures and markets the following lines of
equipment that range in price from $9,000 to $500,000:

      The HC Series:  The HC Series, also known as "Homogenizers," is a
      -------------                                                    
laboratory-scale series of equipment that is intended to impart moderate levels
of energy into a customer's product with greater flow rates than the more energy
intensive Microfluidizers.  Operating pressures of products in the Company's HC
Series can range from under 500 psi to as high as 8,000 psi, and will process as
much as two liters of fluids per minute.

      The 110 Series:  The 110 Series, a laboratory product line, is designed 
      --------------                                                
primarily for research and development applications. The original pneumatically
driven laboratory-scale Microfluidizer has been supplemented by a newer, more
costly, electrically driven unit. Standard models can operate at pressures as
high as 25,000 psi and have a flow rate that exceeds one-half of a liter of
product per minute.

      The M-140K:  The M-140K, introduced in June of 1994, is a laboratory-
      ----------                                                          
scale unit developed for customers in chemical, biotechnology, pharmaceutical,
cosmetic and food processing industries who require elevated operating pressures
to achieve better performance.  The M-140K can achieve operating pressures up to
40,000 psi. The M-140K has a built-in hydraulic system and utilizes a double
ended intensifier pump that provides a highly uniform pressure profile.  It has
been designed with important safety features such as an explosion proof motor,
starter and electrical controls.

      The 210 Series:  The 210 Series is primarily marketed to manufacturers who
      --------------                                                        
have created a successful new or improved formulation on a 110 series unit and
would like to increase their productive capacity. The 210 Series

                                       4
<PAGE>
 
unit is typically used for testing formulations at greater volume levels before
initiating full scale production.  For some customers (such as pharmaceutical
product manufacturers), the 210 series may have the capacity to function as a
production unit.

     The 610 Series:  The 610 Series consists of custom built models used for
     --------------                                                      
large-scale manufacturing.  These units have flow rates of up to 50 gallons
per minute and generate operating pressures up to 40,000 psi.

MARKETING AND SALES:
- ------------------- 

      The Company's strategy is to sell laboratory Microfluidizer systems such
as the 110 Series or the M-140K into customers' research and development
departments where chemists, formulators, scientists and process engineers are
searching for new and better formulations of their products. If the laboratory
Microfluidizer systems are accepted, Microfluidizer systems such as the 210
Series or the 610 Series are introduced into a customer's operations department
where a customer may use Microfluidizer technology for production levels of its
new or improved products.

      Marketing is conducted through advertising, direct mail, seminars, trade
shows and telemarketing. In addition, the Company has an active program of field
demonstrations, as well as demonstrations to potential users in the Company's
applications laboratory. International distributors and sales agents are
supported with trade advertising, collateral literature and trade show
materials. The distributors also advertise directly on their own behalf and
attend regional and international trade shows. As an aid to the marketing and
sales activity for the equipment, the Company provides a complete applications
testing laboratory service. This service includes free processing and analysis
of a prospective customer's sample formulation. Additionally, a prospective
customer may pay for subsequent laboratory time and services on a fee for
services basis, which includes equipment rentals.

      Foreign sales, in general, contributed approximately $2,498,000,
representing approximately 47% of total revenues in 1995.  Sales in Asia
contributed approximately $1,514,000, or 29%, of revenue in 1995.  Sales in
Europe contributed approximately $984,000, or 19%, of revenue in 1995.

CUSTOMERS:
- --------- 

      The Company's customers are companies with processing needs in the
chemical, pharmaceuticals, food, cosmetic and biotechnology industries,
including E.I. DuPont, Polaroid, Kodak, 3M, Burroughs-Wellcome, Chiron, PPG,
Amgen, Genentech and Hershey.  Mizuho Industrial Co., a distributor, accounted
for 21% of revenues in 1995. One other customer (PPG) accounted for 10% of
revenues in 1995.  A reduction or delay in orders from Mizuho or other
significant customers could have a material adverse effect on the Company's
results of operations.

COMPETITION:
- ----------- 

      The Company believes that its Microfluidizer equipment competes with
high and low pressure homogenizers and high energy mechanical dispersing
equipment.  Homogenizers are directly descended from the first milk homogenizer,
introduced around 1900.  Mechanical dispersers employ high shear technology,
which consists of blades rotating in a vessel containing the material to be
dispersed.  The Company believes that machines produced by other manufacturers
have, in general, more moving parts and operate at lower pressures and at less
intense energy.  Colloid mills are also used to produce emulsions and
dispersions.  Other types of rotor-stator mixing equipment, which are sometimes
referred to as low-shear mixers, are generally not competitive in function with
the Company's equipment, but may be useful in pre-mixing product for subsequent
processing by other means.

      With respect to emulsions, the Company believes that, generally, an
emulsion processed with a Microfluidizer unit will exhibit improved stability
characteristics and require reduced concentrations of costly emulsifying agents.
Competing homogenizer equipment operates by impacting the pressurized ejection
of a

                                       5
<PAGE>
 
formulation upon a ring of metal.  The Company believes that these devices have
several operational disadvantages, including variable treatment of formulation
elements, particle size reduction limitations, cleaning difficulty, energy
inefficiency and imprecise temperature control.

      With respect to dispersions, the available competing equipment ("media
mills") uses milling media (beads of ceramic, metal, etc.) to facilitate
dispersion of the solid component in the liquid.  This technology, however,
often results in crushed formulation particles.  In contrast, the Microfluidizer
process does not damage the primary solid.  In addition, when using a media
mill, the media used is often fragmented in the mixing process, thus
contaminating the final dispersion.  Using its fluid stream mixing process, the
Microfluidizer unit avoids the need for an additional processing step to remove
such impurities.

      The Company believes that most competing technologies in cell rupture
processing frequently contaminate the cell contents with membrane debris and/or
by introducing contamination from media breakdown, requiring additional
downstream separation and purification and resulting in lower yield. Further,
such technologies usually require multiple passes to adequately process cells.

      There are several competing technologies that can be used to
manufacture liposomes.  However, the Company believes that these production
methods suffer from their lot size limitations, lack of consistency, requisite
use of detergents or emulsifiers and an inability to operate in a continuous
process mode.  In addition, to the Company's knowledge, only the Microfluidizer
system has demonstrated the ability to produce small, uniform, unilamellar
(single membrane) liposomes on a commercial production scale.

RESEARCH AND DEVELOPMENT:
- ------------------------ 

      The Company's research and development efforts are focused on
developing new mixing techniques for the process industries and further
enhancing the functionality, reliability and performance of existing products.
Research and development costs were $691,446 in 1995.

COOPERATIVE RESEARCH ARRANGEMENTS:
- --------------------------------- 

      The Company subsidizes research and development activities centered
around Microfluidizer technology at a number of research universities.
Currently, the Company is subsidizing research and development in the following
fields at the following universities: The University of Massachusetts, Lowell -
biotechnology; Lehigh University - polymer chemistry; University of Lavaal
(Quebec) - food science; Worcester Polytechnic Institute ("WPI") - catalytic
chemistry; Rutgers University - ceramics; and Purdue University -
pharmaceuticals.  In addition to their research activities, these universities
provide the Company with contacts at industrial companies that may utilize the
Microfluidizer technology.

      Worcester Polytechnic Institute (WPI)
      -------------------------------------

      The Company has supported research and development at WPI since 1988. In
1992, the Company entered into a cooperative venture with WPI to develop, patent
and license for commercial applications the Microfluidizer process technology in
the following fields: (i) the production of catalysts used in chemical and
petroleum processing; (ii) the manufacture of advance ceramic materials; and
(iii) the destruction of volatile organic contaminants in process waste water.
The Company and WPI applied for United States and foreign patents in 1992 and
1993, respectively, which cite the Microfluidizer technology as enabling the
above process technologies. The two applied-for United States patents were both
granted and issued in the United States in 1995. Patent issuance for these
process technologies is either pending or in the latter stages of prosecution in
several foreign jurisdictions.

      Based upon market research and technical evaluation to date, the Company
is focusing its activities on the synthesis of advanced zeolite and metal oxide
catalysts using the WPI process technology. A catalyst is a substance that
initiates, accelerates and determines the course of a chemical reaction. The
Company believes that properties

                                       6
<PAGE>
 
of proprietary catalysts may improve industrial process economics by making more
efficient use of raw materials, reducing energy requirements and increasing
product yields.  The Company believes that the catalytic materials produced by
the Microfluidizer process may result in improved efficiency and extended life,
compared with conventional catalysts.

     Catalytica, Inc.
     ----------------

     In 1993, the Company entered into a licensing agreement with Catalytica,
Inc. and WPI, and concurrently formed a collaboration with Catalytica. WPI
granted to Microfluidics and Catalytica, jointly, an exclusive, worldwide
license to develop and commercialize the Microfluidizer process technology
developed at WPI for the synthesis of nanometer size, high purity, solid state
metal oxide materials. Microfluidics and Catalytica are currently focusing on
technically refining this process with the objectives of producing advanced
catalyst for resale or licensing the process to catalysts manufacturers.

      In November of 1994, the Company and Catalytica were jointly awarded a $2
million matching funds grant under the Advanced Technology Program of the United
States Department of Commerce's National Institute of Standards and Technology.
The Advanced Technology Program is designed to assist in funding emerging,
economically important projects with well defined research and development,
technology and business objectives. The grant was awarded to the Company and
Catalytica to develop and demonstrate the ability, using patented Microfluidizer
equipment, to synthesize nanometer size catalysts providing enhanced performance
for use in the chemical and petroleum refining industries. The project targets
three types of nanometer-size catalysts: mixed metal oxides used in chemical
manufacturing, non-crystalline zeolites used for petrochemical production and
colloidal catalysts used for processing by the petroleum refining industry.
During the remaining two years of the project, the Company has budgeted
expenditures of approximately $320,000 and $350,000, respectively. Under this
grant, the Company will be reimbursed 48% of its expenditures. The first year of
the project sought to demonstrate technical aspects such as synthesis techniques
and catalyst performance, followed by prototyping proof of principle and scale
up for pilot production in year two, and customer evaluation in year three.
There can be no assurances that this project will result in technology useful
for the chemical and petroleum refining industries or that any revenue will be
generated from the results of this project.

     In connection with the Catalytica cooperative venture, the Company has
provided its equipment to the University of Illinois (Champagne Urbana) for
research in the area of cavitational processing.

PATENTS AND PROPRIETARY RIGHTS PROTECTION:
- ----------------------------------------- 

     To protect its proprietary rights, the Company relies on a combination of
U.S. patent laws, trademark laws, trade secrets, confidentiality agreements,
contractual provisions and technical measures, including x-ray transparent
components and a tamper-resistant, self-contained interaction chamber. In the
event of patent infringement or breach of confidentiality, there can be no
assurance that these measures will be adequate or that the Company will have
sufficient resources to prosecute or prevail in an action against a third party.
In addition, the Company has not sought patent or trademark protection for its
interaction chamber in any country other than the United States and, as such,
its proprietary rights are not subject to the protection of patent or trademark
laws of foreign countries where the Company's equipment is sold. The Company's
process patent expires March 13, 2007 and its equipment patent expires August 6,
2002.

MANUFACTURING
- -------------

      At present, the Company subcontracts the manufacture of many of the
components of its equipment to many third parties, with the Company undertaking
the remaining fabrication, assembly and performance testing.  The Company has
selected certain primary suppliers based upon pricing terms and the quality of
their products.  The Company believes that there are adequate available
alternate manufacturing sources and suppliers for the Company's components and
raw materials.

                                       7
<PAGE>
 
GOVERNMENT REGULATION:
- --------------------- 

      Certain of the Company's customers utilize the Microfluidizer equipment in
processes and production that are subject to governmental regulation. For
example, the manufacturing and marketing of pharmaceutical products requires the
approval of the Food and Drug Administration ("FDA") within the United States
and of comparable agencies in foreign countries. The FDA has established
mandatory procedures, safety standards and protocols that apply to the
manufacture, clinical testing and marketing of new pharmaceutical products in
the United States. The process of seeking and obtaining FDA approval of a new
product often takes a number of years and often involves the expenditure of
substantial resources. The FDA approval process contributes to the extremely
long lead times that are attendant to manufacturing equipment orders for these
applications.

      Further, in addition to product approvals, the FDA imposes requirements as
to manufacturing practices, record keeping and reporting ("Good Manufacturing
Practices" or "GMP"). GMP-regulated companies are subject to inspections by the
FDA (inclusive of Microfluidizer equipment) and product approvals may be
withdrawn if GMP are not met.

      At present, the Company's customers include several companies who are
making FDA approved drugs and preparations for external use and a few companies
who utilize Microfluidizer equipment for the formulation or production of FDA
approved parenteral (injectable) drugs or compounds.

      Various laws, regulations and recommendations relating to safe working
conditions, laboratory practices and the purchase, storage, movement, import and
export, use and disposal of harmful or potentially harmful substances that may
be used in connection with the Company's research work are or may be applicable
to its activities.  These laws include, among others, the United States Atomic
Energy Act, the Clean Air Act, the Clean Water Act, the Occupational Safety and
Health Act, the National Environmental Policy Act, the Toxic Substances Control
Act, the Resource Conservation and Recovery Act, national restrictions on
technology transfer, import, export and customs regulations and other present
and possible future local, state or Federal regulation.  The extent of adverse
governmental regulation which might result from future legislation or
administrative action cannot be accurately predicted.  Certain agreements that
may be entered into by the Company involving exclusive license rights may also
be subject to national or supranational antitrust regulatory control, the effect
of which cannot be predicted.

BACKLOG:
- ------- 

      The Company's backlog of accepted and unfilled orders at March 26, 1996
and March 20, 1995 was $635,697 and $435,627, respectively. Revenue is not
recognized until equipment is shipped. Backlog as of any particular date should
not be relied upon as indicative of the Company's net revenues for any future
period.

EMPLOYEES:
- --------- 

      The Company has approximately 35 full-time employees. None of the
Company's employees are covered by a collective bargaining agreement, and the
Company considers its relations with its employees to be excellent. The Company
believes that its future success will depend in large part on its ability to
attract and retain highly skilled employees.

ITEM 2.  PROPERTIES

      The Company rents approximately 32,000 square feet of offices, production
and research and development facilities in Newton, Massachusetts for
administrative, development and production activities at an annual expense of
approximately $150,000. The lease term expires on May 31, 1998. The Company
believes that this facility will be adequate for operations for the next three
years.

                                       8
<PAGE>
 
ITEM 3.  LEGAL PROCEEDINGS

Not applicable.

ITEM 4.  SUBMISSION OF MATTERS TO VOTE OF SECURITY HOLDERS

Not applicable.


                                    PART II

ITEM 5.  MARKET FOR REGISTRANT'S COMMON EQUITY AND RELATED
         STOCKHOLDER MATTERS

     Until January 17, 1994, the Company's Common Stock was traded on the Nasdaq
Small Cap Market.  Thereafter, the Company's Common Stock was traded on the
Nasdaq Stock Market under the symbol MFIC.  The following table sets forth the
range of quarterly high and low bid quotations for the period from January 1,
1994 to December 31, 1995, as furnished by the National Association of
Securities Dealers Automated Quotation System.  The quotations represent
interdealer quotations without adjustment for retail markups, markdowns, or
commissions, and may not necessarily represent actual transactions.
<TABLE>
<CAPTION>
 
<S>                 <C>       <C>     <C>     <C>     <C>     <C>     <C>     <C>
Quarters Ended      12/31     9/30    6/30    3/31    12/31   9/30    6/30    3/31
                    1995      1995    1995    1995    1994    1994    1994    1994
 
Common Stock
Low                 1-15/32   2-7/8   3-1/8   3-1/2   3       4       4-1/2   5
High                3-5/8     4-3/8   4-3/8   4-3/8   4-5/8   5-5/8   6-3/4   7-1/2
</TABLE>

     As of March 26, 1996 there were approximately 486 holders of record of the
Company's Common Stock.

     The Company has never paid any cash dividends on its capital stock and
presently anticipates that no dividends on its Common Stock will be declared in
the foreseeable future.  The Company's current policy is to retain all of its
earnings to finance future growth.  In addition, the Company's arrangement with
its commercial lender prohibits the payment of dividends without prior approval.

                                       9
<PAGE>
 
ITEM 6.  SELECTED FINANCIAL DATA

     The selected financial information presented below is derived from the
consolidated financial statements of the Company for the five years ended
December 31, 1995.  The information set forth below should be read in
conjunction with "Management's Discussion and Analysis of Financial Condition
and Results of Operations" included as Item 7 and the financial statements and
related notes included elsewhere in this Form 10-K.

SELECTED INCOME STATEMENT DATA
<TABLE>
<CAPTION>
 
 
                                           Year Ended        Year Ended       Year Ended        Year Ended        Year Ended
                                           December 31,     December 31,     December 31,      December 31,      December 31,
                                               1995            1994              1993              1992              1991
<S>                                        <C>              <C>                <C>             <C>                <C>    
Total Revenues........................      $ 5,273,399      $7,298,416       $6,778,098        $4,496,645        $2,766,102
Operating expenses....................        6,556,747       6,796,397        5,897,569         4,085,009         3,245,749
Operating income (loss)...............       (1,283,348)        502,019          880,529           411,636          (479,647)
Net interest..........................           98,675          43,608           23,705             6,977           (14,826)
Gain on sale of investments and                              
 assets...............................          174,776                          34,096            94,599
                                            -----------      ----------       ----------        ----------        ----------
Net income (loss) before taxes and                           
 extraordinary item...................       (1,009,897)        545,627          938,330           513,212          (495,689)
Income tax benefit (provision)........       (1,107,422)        791,058          (55,979)         (211,058)           21,649
Net income (loss) before                                     
 extraordinary item and cumulative                           
 effect of accounting change..........       (2,117,319)      1,336,685          882,351           302,154          (474,040)
                                                             
Extraordinary item....................                                                             186,807
Cumulative effect of change in                               
 accounting for income taxes..........                                           290,609
                                            -----------      ----------       ----------        ----------        ---------- 
Net income (loss).....................      ($2,117,319)     $1,336,685       $1,172,960        $  488,961        $ (474,040)
                                            ===========      ==========       ==========        ==========        ==========
                                                             
Net income (loss per primary share                           
 before extraordinary item and                               
 cumulative effect of an                                     
 accounting change....................      $      (.43)     $      .26       $      .20        $      .08        $     (.15)
Extraordinary item per primary                               
 share................................                                                                 .05
Cumulative effect of change in                               
 accounting for income taxes per                             
 primary share........................                                               .07
                                            -----------      ----------       ----------        ----------        ----------  
Net income (loss) per primary share...      $      (.43)     $      .26       $      .27        $      .13        $     (.15)
                                            ===========      ==========       ==========        ==========        ========== 
SELECTED BALANCE SHEET DATA                                  
                                                             
Working Capital.......................      $ 5,599,714      $6,626,006       $5,758,763        $2,371,938        $1,590,703
Total Assets..........................        6,715,986       9,192,505        7,455,910         3,714,664         2,365,628
Long term obligations.................                                                                            $  722,780
Stockholders' equity..................      $ 6,029,081      $8,069,524       $6,467,414        $2,735,827        $1,301,918
</TABLE>

                                       10
<PAGE>
 
ITEM 7.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND
         RESULTS OF OPERATIONS

     OVERVIEW
     --------

     1995 was a year of conscientious change in strategy and in the way that the
Company conducts its business.  What was expected to be a year of both growth
and profitability, based upon investments made in 1994, did not materialize.

     The most significant factor that affected 1995 results from operations was
a 28% decline in revenue from the previous year level.  This revenue decline was
primarily in North America and was reflected in lower system shipments in most
product line categories.  Fourth quarter sales rose to higher levels than those
posted in the third quarter.

     Significant management changes took place in 1995.  In July, the Company's
President resigned.  Michael A. Lento was appointed President in September 1995.
Mr. Lento had been Vice President of Marketing at the Company since September
1994 and prior to that had managed the Company's cooperative venture with
Catalytica, Inc.  Subsequent management changes have included the resignation of
the Company's Vice President of Engineering, Vice President of Sales, and
Controller.  The Controller position has been filled and the Company is
currently interviewing candidates for the other positions.

     Within the Unites States in 1995, the Company shifted from a predominantly
direct sales force to the appointment and use of manufacturers representatives
and sales agents with previous experience in the sale of materials processing
equipment.  Sales activity and performance in the Company's overseas markets
remain stable and in Europe are showing signs of growth.  The Company has
strengthened its relationships with its existing distributors in Asia.  In
Europe, the Company has replaced a number of sales agents that were not
performing at acceptable levels, while also appointing several additional sales
agents.  The Company's new sales agents, together with the efforts of the
Company's resident European manager in Frankfurt, have increased the Company's
activities in Europe and the Company believes that it can achieve significant
growth in this market.

     The Company's cash and cash equivalent position rose in 1995 by almost
$230,000 to over $1,900,000.  In light of the Company's debt-free balance sheet,
the Company believes that it has adequate resources and reserves to allow it to
accomplish its business plan.

     The Company has adopted a customer-focused approach to reaching a broader
market base with its message of "Innovation through Microfluidizer/(R)/
technology".

                                       11
<PAGE>
 
RESULTS OF OPERATIONS

     FISCAL 1995 COMPARED TO FISCAL 1994
     -----------------------------------

     Total revenue for fiscal 1995 was $5,273,399, as compared to $7,298,416 in
fiscal 1994, a decrease of $2,025,017, or approximately 28%.  This decline was
primarily the result of a decrease in North American revenues from approximately
$4,753,000 in 1994 to $2,775,000 in 1995.

     Sales of both the 110 Series and 210 Series decreased by approximately
$857,000 from 1994 to 1995. In addition, the Company's sale of large volume
production units in fiscal 1995 was two units, down from five units in fiscal
1994, and represented a decrease of approximately $840,000. Foreign revenue for
the year was $2,497,248, representing approximately 47% of total revenue, as
compared to $2,543,566 or 35% of total revenue in fiscal 1994. The increase in
foreign revenues as a percentage of sales was significantly impacted by a
corresponding decrease in North American sales.

     Cost of goods sold for fiscal 1995 was $2,813,801, or 53% of revenue, as
compared to $2,968,030, or 41% of revenue, in fiscal 1994.  This increase was
primarily the result of an increase in material costs and direct labor as a
percentage of sales, and the write off of obsolete inventory.  The Company's
product lines each have different profit margins, as well as multiple profit
margins within each product line.  In year-to-year comparisons, there may be
significant changes in the cost of goods sold as a percentage of revenue,
depending on the mix of products sold.  Generally, full scale production units
yield lower profit margins than laboratory or pilot production units and
electric hydraulic units yield lower profit margins than air driven units.

     Operating expenses for fiscal 1995 were $3,742,946 as compared to
$3,828,367 for fiscal 1994, a decrease of $85,421, or 2%.  Research and
development expenses decreased to $691,466 in fiscal 1995 from $762,620 in
fiscal 1994, primarily due to a grant reimbursement from the United States
Department of Commerce in the amount of $118,638 for 1995 in connection with the
Company's continued research efforts with Worcester Polytechnic Institute and
Catalytica, Inc.  Sales and Marketing expenses increased to $1,895,274, or 36%
of revenue, from $1,764,060, or 24% of revenue, in fiscal 1994 as a result of
the Company's continued efforts to expand and strengthen its sales force.
General and administrative expenses deceased to $1,156,206 in fiscal 1995 from
$1,301,687 in fiscal 1994.

     Interest income increased 115% to $98,675 in fiscal 1995 from $43,608 in
fiscal 1994, reflecting the amount of cash available for investment due to the
collection of accounts receivable in 1995.  There were no interest expenses
incurred in either fiscal 1995 or fiscal 1994.

     In fiscal 1995, the Company recognized a gain of $93,239 on the sale of a
portion of its holdings in PolyMedica Industries, Inc. The market value for the
remaining 13,940 shares owned by the Company at December 31, 1995 was $83,640.

     On December 27, 1995, the Company sold to ChemMark Development, Inc.
("ChemMark") its business of manufacturing and distributing proprietary cosmetic
liposomal formulations, sold under the trade name Dermasome/(R)/. In return for
ChemMark's payment of $50,000, the Company transferred to ChemMark its
Dermasome/(R)/ trademark, its customer list, its products list, all unfilled
Dermasome/(R)/ orders, and all products and product literature. Additionally,
the Company granted to ChemMark a two year, world-wide, exclusive license to use
the Company's proprietary technology and know-how to manufacture and

                                       12
<PAGE>
 
distribute Dermasome products.  In exchange, the Company received a one-time,
non-refundable $50,000 rights grant acquisition fee, and the payment over the
license term of a percentage royalty equal to ten percent (10%) of the net sales
realized by ChemMark on the sale of products derived from the Company's
technology.  Notwithstanding the amount of such percentage royalty, ChemMark is
obligated to pay a minimum royalty payment in the amount of $100,000, payable in
22 equal monthly installments of $4,167.67, with a final payment of $8,333.34
due upon the second anniversary of the agreement.  As security for ChemMark's
performance of its obligations to the Company, the Company retains a security
interest in the Trademark.  The Company recognized a gain of $81,537 upon the
sale of the Dermasome/(R)/ business.

     The tax provision of $1,107,422 principally results from the recording of a
valuation allowance for net operating loss carryforwards, tax credit
carryforwards, and other deferred tax assets, which may not be realized.

LIQUIDITY AND CAPITAL RESOURCES

     The cash and cash equivalents balance at December 31, 1995 was $1,903,418,
an increase of $229,607 from the December 31, 1994 balance of $1,673,811. This
increase was the result of a reduction in accounts receivables (from $2,991,184
at December 31, 1994 to $1,751,199 at December 31, 1995, a decrease of 41%) of
over $1,197,000, as well as proceeds of $100,000 related to the sale and license
transaction related to the Dermasome/(R)/ business and a $93,239 gain on the
sale of 10,000 shares of PolyMedica Industries, Inc. stock. The Company
continues to maintain a line of credit with the Bank of Boston equal to the
lesser of $750,000 or 80% of the domestic accounts receivable that are less than
60 days old. The available line, as of March 26, 1996, was $276,796. The
accounts receivable balance as of March 26, 1996 was $1,222,973. Inventory
decreased by 14% due to a decrease in sales and improved controls over inventory
levels. Accounts payable decreased by 48% primarily due to a decrease in
inventory.
     
     The Company may, from time to time, consider acquisition of complementary
businesses, products or technologies, although it has no present understandings,
commitments or agreements with respect to any such acquisitions.  The Company
believes that anticipated cash flows from operations and current sources of
liquidity will be adequate to fund operations for at least the next year.


     FISCAL 1994 COMPARED TO FISCAL 1993
     -----------------------------------

     Total revenue increased $520,318, or approximately 8%, to $7,298,416 in
fiscal 1994 from $6,778,098 in fiscal 1993.  This increase was primarily the
result of a 27% increase in the sale of electric hydraulic laboratory and pilot
production units and related spare parts over fiscal 1993 levels.  The
Company's sale of five full production units in fiscal 1994 was down from eight
such sales in fiscal 1993.  Foreign revenue for the year was $2,543,566,
representing approximately 35% of total revenue, as compared to $2,286,994, or
34% of total revenue, in fiscal 1993.  The increase in foreign revenues was
significantly impacted by one additional sale of a full scale production unit.

                                       13


<PAGE>
 
     Cost of goods sold for fiscal 1994 was $2,968,030, or 41% of revenue, as
compared to $2,922,298, or 43% of revenue, in fiscal 1993.  Operating expenses
for fiscal 1994 were $3,828,367, as compared to $2,975,271 for fiscal 1993, an
increase of $853,096, or 29%.  Research and development expenses increased 78%
to $762,620 in fiscal 1994 from $427,568 in fiscal 1993, primarily due to a
$180,000 expenditure in connection with the Company's continued research efforts
with Worcester Polytechnic Institute and Catalytica, Inc. and the Company's
internal developments, including the Diamond Interaction Chamber and a number of
design enhancements to its existing products.  Sales and marketing expenses
increased 39% to $1,764,060 (24% of revenue) in fiscal 1994 from $1,268,804 (19%
of revenue) in fiscal 1993. This increase resulted from the Company's efforts in
1994 to expand and strengthen its sales force.  General and administrative
expenses increased 2% to $1,301,687 in fiscal 1994 from $1,278,899 in fiscal
1993.

     Interest income increased 84% to $43,608 in fiscal 1994 from $23,705 in
fiscal 1993, reflecting the amount of cash available for investment due to the
private placement the Company completed in fiscal 1993.  There were no interest
expenses incurred in either fiscal 1994 or fiscal 1993.

     In fiscal 1993, the Company recognized a gain of $34,096 on the sale of a
portion of its holdings in PolyMedica Industries, Inc.  There were no sales of
these shares in fiscal 1994.  The market value for the remaining 23,940 shares
owned by the Company at December 31, 1994 was $104,738.

     In 1993 the Company adopted the liability method of accounting for income
taxes in accordance with Statement of Financial Accounting Standards No. 109,
"Accounting for Income Taxes."  SFAS 109 requires the recognition of deferred
tax assets (net of any valuation allowance) and liabilities based on the
expected future tax consequences of events that have been included in the
financial statements or tax returns.  Under this method, deferred tax assets and
liabilities are determined based upon the difference between the financial
statement and tax basis of assets and liabilities using the expected tax rates
in effect for the year in which the differences are expected to reverse.  The
effect of adopting SFAS 109 resulted in a cumulative increase in book income of
$290,609 for 1993.

     The Company's provision/(benefit) for income taxes was due mainly to its
continued profitability through 1994.  Therefore, the majority of prior years
valuation allowance under SFAS 109 was no longer required.  The deferred benefit
related to the release of the valuation allowance for 1995 was $728,151.

     The accounts receivable balance at December 31, 1994 was $2,991,184, an 85%
increase over the balance of $1,616,208 at December 31, 1993.  The majority of
this increase was due to sales for full scale production units in the latter
half of the fourth quarter of 1994, which are on different payment terms.  The
accounts receivable balance as of March 20, 1995 was $1,208,092.  Inventory
increased by 57% due to anticipated fourth quarter orders that did not
materialize. Accounts payable increased by 32%, primarily due to the increase in
inventory. Customer advances decreased by approximately 40% primarily because
advance payments received in 1993 were offset against final invoices issued when
full scale production units were shipped in 1994. The customer advance
represented an overpayment on behalf of a customer.

NEW ACCOUNTING PRONOUNCEMENTS

     Statement of Financial Accounting Standards No. 123 "Accounting for Stock-
Based Compensation" (SFAS 123), will require the Company to either elect expense
recognition or the disclosure-only alternative for stock-based employee
compensation.  SFAS 123 must be adopted in the

                                       14
<PAGE>
 
Company's 1996 financial statements with comparable disclosures for the prior
year.  While the Company is reviewing the adoption and impact of SFAS 123, it
expects to adopt the disclosure-only alternative and, accordingly, this standard
will have no impact on the Company's results of operations or its financial
position.

BUSINESS OUTLOOK

     This report contains forward-looking statements within the meaning of the
"safe-harbor" provisions of the Private Securities Litigation Reform Act of
1995.  Such statements are based on management's current expectations and are
subject to a number of factors and uncertainties that could cause actual results
to differ materially from those described in the forward-looking statements.
Such factors and uncertainties include, but are not limited to, the uncertainty
that the performance advantages of the Microfluidizer equipment will be realized
commercially or that a commercial market for Microfluidizer equipment will
continue to develop; the dependence by the Company on key customers; the loss of
the services of one or more of the Company's key employees, which could have a
material adverse impact on the Company; the development of competing or superior
technologies and products from manufacturers, many of which have substantially
greater financial, technical and other resources than the Company; the cyclical
nature of the materials processing industry, which has historically negatively
affected the Company's sales of Microfluidizer equipment during industry
downturns and which could do so in the future; the availability of additional
capital to fund expansion on acceptable terms, if at all; and general economic
conditions.

ITEM 8.   FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA

    The following consolidated financial statements of the Company and its
subsidiaries appear on the following pages of this Form 10-K.

<TABLE>
<CAPTION>
                                                                    Page
<S>                                                               <C>
 
Report of Independent Accountants                                 F-1
 
Consolidated Balance Sheets as of December 31, 1995 and 1994      F-2 & F-3
 
Consolidated Statements of Operations for the years ended
    December 31, 1995, 1994 and 1993                              F-4
 
Consolidated Statements of Cash Flows for the years ended
    December 31, 1995, 1994 and 1993                              F-5
 
Consolidated Statements of Changes in Stockholders' Equity
    for the years ended December 31, 1995, 1994 and 1993          F-6
 
Notes to Consolidated Financial Statements                        F-7
</TABLE>

ITEM 9.  CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON
         ACCOUNTING AND FINANCIAL DISCLOSURE

     Not applicable.

                                       15
<PAGE>
 
                                   PART III

ITEM 10.  DIRECTORS AND EXECUTIVE OFFICERS OF THE REGISTRANT

DIRECTORS
- ---------

     The information concerning directors of the Company required under this
item is incorporated herein by reference to the Company's definitive proxy
statement pursuant to Regulation 14A, to be filed with the Commission not later
than 120 days after the close of the Company's fiscal year ended December 31,
1995.

EXECUTIVE OFFICERS
- ------------------

     The information concerning executive officers of the Company required under
this item is incorporated herein by reference to the Company's definitive proxy
statement pursuant to Regulation 14A, to be filed with the Commission no later
than 120 days after the close of the Company's fiscal year ended December 31,
1995.

ITEM 11.  EXECUTIVE COMPENSATION

     The information required under this item is incorporated herein by
reference to the Company's definitive proxy statement pursuant to Regulation
14A, to be filed with the Commission not later than 120 days after the close of
the Company's fiscal year ended December 31, 1995.

ITEM 12.  SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND
          MANAGEMENT

     The information required under this item is incorporated herein by
reference to the Company's definitive proxy statement pursuant to Regulation
14A, to be filed with the Commission not later than 120 days after the close of
the Company's fiscal year ended December 31, 1995.

ITEM 13.  CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

     The information required under this item is incorporated herein by
reference to the Company's definitive proxy statement pursuant to Regulation
14A, to be filed with the Commission within 120 days after the close of the
Company's fiscal year ended December 31, 1995.


                                    PART IV

ITEM 14.  EXHIBITS, FINANCIAL STATEMENT SCHEDULES AND REPORTS ON
          FORM 8-K

     (a)1. CONSOLIDATED FINANCIAL STATEMENTS.

           The following financial statements are included in Item 8:

                Consolidated Balance Sheets as of December 31, 1995 and 1994

                                       16
<PAGE>
 
                Consolidated Statements of Operations for the years ended
                December 31, 1995, 1994 and 1993

                Consolidated Statements of Cash Flows for the years ended
                December 31, 1995, 1994 and 1993

                Consolidated Statements of Changes in Stockholders' Equity for
                the years ended December 31, 1995, 1994 and 1993

                Notes to Consolidated Financial Statements

                Report of Independent Accountants

    (a)2.  FINANCIAL STATEMENT SCHEDULES.

           All schedules are omitted because they are not applicable or the
           required information is shown in the financial statements or the
           notes thereto.

    (a)3.  LIST OF EXHIBITS.

   Exhibit
   Number   Description of Exhibit
   ------   ----------------------

   3.3(a)   Certificate of Incorporation for the Company, as amended (filed as
            Exhibit 2A to Registration Statement No. 0-11625 on Form 8-A and
            incorporated herein by reference).

   3.3(b)   By-Laws for the Company, as amended (filed as Exhibit 3(b) to
            Registration Statement No. 2-85290 on Form S-1 and Incorporated
            herein by reference).

   3.10(a)  1987 Stock Plan (filed as Exhibit 10(g) to the Company's Annual
            Report on Form 10-K for the fiscal year ended December 31, 1987 and
            incorporated herein by reference).

   3.10(b)  1988 Stock Plan (filed as Exhibit 10(g) to the Company's Annual
            Report on Form 10-K for the fiscal year ended December 31, 1988 and
            incorporated herein by reference).

   3.10(c)  1989 Non-Employee Directors Stock Option Plan (filed as Exhibit
            10(h) to the Company's Annual Report on Form 10-K for the fiscal
            year ended December 31, 1988 and incorporated herein by reference).

   3.10(d)  Loan Agreement between The First National Bank of Boston and
            Microfluidics International Corporation dated as of December 10,
            1993 (filed as Exhibit 10.1 to Form 8-K filed on December 27, 1993
            and incorporated herein by reference).

   3.10(e)  Lease for 30 Ossipee Road, Newton, Massachusetts dated April 22,
            1993 between Microfluidics International Corporation and J. Frank
            Garrity, Trustee of 1238 Chestnut Street Trust under Declaration of
            Trust dated May 23, 1969, recorded with Middlesex South Registry of
            Deeds in Book 11682, Page 384 (filed as Exhibit 3.10(e) to the

                                       17
<PAGE>
 
            Company's Form 10-K for the fiscal year ended December 31, 1993 and
            incorporated herein by reference).

   3.10(f)  Letter of Understanding between Microfluidics International
            Corporation and Worcester Polytechnic Institute dated as of April 3,
            1993 (filed as Exhibit 3.10(f) to the Company's Form 10-K for the
            fiscal year ended December 31, 1993 and incorporated herein by
            reference).

   3.10(g)  Agreement between Microfluidics International Corporation and
            Catalytica, Inc. dated as of October 18, 1993 (filed as Exhibit
            3.10(g) to the Company's Form 10-K for the fiscal year ended
            December 31, 1993 and incorporated herein by reference).

   3.10(h)  License Agreement among Microfluidics International Corporation,
            Worcester Polytechnic Institute and Catalytica, Inc. dated as of
            October 18, 1993 (filed as Exhibit 3.10(h) to the Company's Form 10-
            K for the fiscal year ended December 31, 1993 and incorporated
            herein by reference).

  *3.10(i)  Agreement, dated July 27, 1995, between Microfluidics
            International Corporation and Michael T. Rumley.

  *3.10(j)  Letter, dated August 16, 1995, from Microfluidics International
            Corporation to Michael T. Rumley.

  *3.10(k)  Letter, dated December 31, 1995, from Microfluidics International
            Corporation to Irwin J. Gruverman.

  *3.10(l)  Warrant for the Purchase of Shares of Common Stock, dated July 15,
            1993, in favor of Ladenburg, Thalman & Co. Inc.

  *3.21     Subsidiaries of the Registrant.

  *3.24     Consent of Coopers & Lybrand L.L.P.

  *3.27     Financial Data Schedule
_____________________
 * Filed herewith


    (b)   REPORTS ON FORM 8-K.

          Not applicable.

    (c)   EXHIBITS.

          The Company hereby files as part of this Form 10-K the Exhibits listed
          in Item 14(a)(3) as set forth above.

    (d)   FINANCIAL STATEMENT SCHEDULES.

                                       18
<PAGE>
 
          See (a)(2) above.

                                       19
<PAGE>
 
      
                       REPORT OF INDEPENDENT ACCOUNTANTS
                       ---------------------------------

To the Board of Directors and
Stockholders of Microfluidics
International Corporation:

We have audited the accompanying consolidated balance sheets of Microfluidics
International Corporation and Subsidiaries as of December 31, 1995 and 1994, and
the related consolidated statements of operations, stockholders' equity, and
cash flows for each of the three years in the period ended December 31, 1995.
These financial statements are the responsibility of the Company's management.
Our responsibility is to express an opinion on these financial statements based
on our audits.

We conducted our audits in accordance with generally accepted auditing
standards.  Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements are free of material
misstatement.  An audit includes examining, on a test basis, evidence supporting
the amounts and disclosures in the financial statements.  An audit also includes
assessing the accounting principles used and significant estimates made by
management, as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.

In our opinion, the financial statements referred to above present fairly, in
all material respects, the consolidated financial position of Microfluidics
International Corporation and Subsidiaries as of December 31, 1995 and 1994, and
the consolidated results of their operations and their cash flows for each of
the three years in the period ended December 31, 1995, in conformity with
generally accepted accounting principles.

                                    COOPERS & LYBRAND L.L.P.


Boston, Massachusetts
February 23, 1996

                                      F-1
<PAGE>
 
MICROFLUIDICS INTERNATIONAL CORPORATION
CONSOLIDATED BALANCE SHEETS
<TABLE>
<CAPTION>
 
                                                             December 31,
                                                           1995        1994
                                                        ---------   -----------
<S>                                                     <C>         <C>
 
ASSETS
 
Cash and cash equivalents                               $1,903,418   $1,673,811
Marketable securities (Note C)                              83,640      104,738
Accounts receivable (less allowance of $47,382
    and $5,464 in 1995 and 1994, respectively)           1,751,199    2,991,184
Other receivables                                           29,820       26,838
Inventory (Note D)                                       2,456,389    2,844,689
Prepaid expenses                                            62,153      107,727
                                                        ----------   ----------
    Total current assets                                 6,286,619    7,748,987
Equipment and leasehold improvements, at cost
    Furniture, fixtures and office equipment               297,228      219,450
    Machinery and equipment                                223,829      198,706
    Leasehold improvements                                 111,249      110,403
                                                        ----------   ----------
                                                           632,306      528,559
Less:  Accumulated depreciation and amortization          (457,910)    (418,637)
                                                        ----------   ----------
                                                           174,396      109,922
Patents, licenses and other intangible assets (net of   
    accumulated amortization of $296,218 in 1995
    and $369,476 in 1994 (Note E)                          254,971      229,062
 
Deferred tax asset (Note I)                                           1,104,534
                                                        ----------   ----------
    Total assets                                        $6,715,986   $9,192,505
                                                        ==========   ==========
</TABLE>

   The accompanying notes are an integral part of the financial statements.

                                      F-2
<PAGE>
 
MICROFLUIDICS INTERNATIONAL CORPORATION
CONSOLIDATED BALANCE SHEETS (CONTINUED)
<TABLE>
<CAPTION>
 
 
                                                             December 31,
                                                           1995        1994
                                                        ---------   -----------
<S>                                                     <C>         <C> 
LIABILITIES AND STOCKHOLDERS' EQUITY
 
Accounts payable and accrued expenses                  $   513,640  $   994,005
Accrued compensation                                       124,555        6,433
Accrued vacation pay                                        48,710       62,300
Income taxes payable                                                     12,243
Customer advance                                                         48,000
                                                       -----------   ----------
    Total current liabilities                              686,905    1,122,981
Commitments and contingencies (Note L)
 
Stockholders' equity (Notes G, J and K)
 
    Common Stock, par value $.01 per share,
    20,000,000 shares authorized; 5,058,203
    and 5,021,348 shares issued and outstanding
    in 1995 and 1994, respectively                          50,582       50,212
 
Additional paid-in capital                              10,319,350   10,254,572
Accumulated deficit                                     (3,969,920)  (1,852,601)
Unrealized appreciation on marketable securities            83,640       62,843
Less:  Treasury Stock, at cost, 107,019 and 101,839
    at December 31, 1995 and 1994,
    respectively (Note J)                                 (454,571)    (445,502)
                                                       -----------  ----------- 
    Total stockholders' equity                           6,029,081    8,069,524
                                                       -----------  -----------
     Total liabilities and stockholders' equity        $ 6,715,986  $ 9,192,505
                                                       ===========  ===========
</TABLE>


The accompanying notes are an integral part of the financial statements.

                                      F-3
<PAGE>
 
MICROFLUIDICS INTERNATIONAL CORPORATION
CONSOLIDATED STATEMENTS OF OPERATIONS
<TABLE>
<CAPTION>
                                                                        Years ended December 31,
                                                                    1995          1994         1993
                                                                -----------    ----------   ----------
<S>                                                             <C>            <C>          <C>
Revenues                                                        $ 5,273,399    $7,298,416   $6,778,098
 
Cost of goods sold                                                2,813,801     2,968,030    2,922,298
Research and development                                            691,466       762,620      427,568
Selling, general and administrative                               3,051,480     3,065,747    2,547,703
                                                                -----------    ----------   ----------
Total cost and expenses                                           6,556,747     6,796,397    5,897,569
                                                                -----------    ----------   ----------
 
Income (loss) from operations                                    (1,283,348)      502,019      880,529

Interest income                                                      98,675        43,608       23,705
Gain on sale of investments (Note C)                                 93,239                     34,096
Gain on sale of assets (Note N)                                      81,537
                                                                -----------    ----------   ----------
Income (loss) before income taxes                                (1,009,897)      545,627      938,330
Income tax benefit (provision) (Note I)                          (1,107,422)      791,058      (55,979)
                                                                -----------    ----------   ----------
Income (loss) before cumulative effect
    of an accounting change                                      (2,117,319)    1,336,685      882,351
Cumulative effect of change in accounting
    for income taxes (Note I)                                                                  290,609
                                                                -----------    ----------   ----------
Net income (loss)                                               $(2,117,319)   $1,336,685   $1,172,960
                                                                ===========    ==========   ==========
 
Income (loss) per Common Share
 
  Primary:
    Average shares outstanding                                    4,939,989     5,047,849    4,363,322
    Income (loss) before cumulative
       effect of an accounting change                           $      (.43)   $      .26   $      .20
    Cumulative effect of change in
       accounting for income taxes                                                                 .07
                                                                -----------    ----------   ----------
    Net income (loss) per Primary Share                         $      (.43)   $      .26   $      .27
                                                                ===========    ==========   ==========
 
  Fully diluted:
 
    Average shares outstanding                                    4,939,989     4,998,689    4,363,359
    Income (loss) before extraordinary
       item and cumulative effect of
       an accounting change                                     $      (.43)   $      .26   $      .20
    Cumulative effect of change in
       accounting for income taxes                                                                 .07
    Extraordinary item
                                                                -----------    ----------   ----------
    Net income (loss) per Fully diluted Share                   $      (.43)   $      .26   $      .27
                                                                ===========    ==========   ==========
</TABLE>

The accompanying notes are an integral part of the financial statements.

                                      F-4
<PAGE>
 
MICROFLUIDICS INTERNATIONAL CORPORATION
CONSOLIDATED STATEMENTS OF CASH FLOWS

<TABLE>
<CAPTION>
                                                                    Years ended December 31,
                                                               1995           1994          1993
                                                              -----           ----          ----
<S>                                                        <C>            <C>            <C>
Cash flows from (used by) operations:                                     
Net income (loss)                                          $(2,117,319)   $ 1,336,685    $1,172,960
Reconciliation of net income (loss) to cash                               
  used by operations:                                                     
Depreciation and amortization                                   93,410         80,528        76,174
Compensation paid in Common Stock                                                            45,000
Bad debt expense                                                40,000                        6,000
Gain on sale of investments                                    (93,239)                     (34,096)
Gain on sale of assets                                         (81,537)   
Change in accounting for income tax                                                        (290,609)
Income tax (benefit) provision                               1,146,429       (805,820)
Changes in operating working capital items:                               
  (Increase) decrease receivables,                                        
    and other receivables                                    1,197,003     (1,401,814)     (315,391)
  (Increase) decrease inventories                              388,300     (1,032,354)     (371,019)
  (Increase) decrease prepaid expenses                          45,574         13,946       (86,111)
  Increase (decrease) current liabilities                     (436,076)       134,485         9,659
                                                           -----------    -----------    ----------
Net cash from (used by) operations                             182,545     (1,674,344)      212,567
Cash flows from (used by) investing activities:                           
Purchase of intangibles                                        (96,680)   
Proceeds from sale of investments                               93,239                       34,096
Proceeds from sale of assets                                   101,800    
Capital equipment and leasehold improvements                  (107,376)       (51,470)      (80,327)
                                                           -----------    -----------    ----------
Net cash (used by) investing activities                         (9,017)       (51,470)      (46,231)
Cash flows from (used by) financing activities:                           
Issuance of Common Stock under employee stock                             
  purchase plan                                                 21,724         21,740         9,071
Issuance of Common Stock under employee stock                             
  option plan                                                   42,729        180,842        67,977
Issuance of Common Stock upon the exercise of                             
  options                                                                                   172,500
Treasury stock purchased                                        (8,374)                     (37,604)
Issuance of Common Stock through Private                                  
  Placement                                                                               2,296,683
                                                           -----------    -----------    ----------
Net cash from (used by) financing activities                    56,079        202,582     2,508,627
                                                                          
Net increase (decrease) in cash and cash                                  
  equivalents                                                  229,607     (1,523,232)    2,674,963
Cash and cash equivalents at beginning of year               1,673,811      3,197,043       522,080
                                                           -----------    -----------    ----------
Cash and cash equivalents at end of year                   $ 1,903,418    $ 1,673,811    $3,197,043
                                                           ===========    ===========    ==========
Supplemental disclosure of cash flow information:
Cash paid during the year for corporate income
  taxes                                                             --    $    42,000    $   50,500
                                                           ===========    ===========    ==========
Common Stock issued for consulting services                                        --    $   45,000
                                                           ===========    ===========    ==========
Treasury stock acquired by the exercise                                   
  of employees' stock repurchases (Note J)                 $     (695)    $   (52,500)   $ (355,647)
                                                           ===========    ===========    ==========
</TABLE>

   The accompanying notes are an integral part of the financial statements.

                                      F-5
<PAGE>
 
MICROFLUIDICS INTERNATIONAL CORPORATION
CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY

for the years ended December 31, 1995, 1994 and 1993

<TABLE>
<CAPTION>
                                                                                                  NUMBER
                                                                                    UNREALIZED      OF
                                NUMBER OF   COMMON                                    APPRE-      SHARES
                                SHARES OF    STOCK    ADDITIONAL                    CIATION ON      OF
                                 COMMON      AT PAR     PAID-IN      ACCUMULATED    MARKETABLE   TREASURY    TREASURY
                                  STOCK      VALUE      CAPITAL        DEFICIT      SECURITIES    STOCK        STOCK        TOTAL
                                ---------   -------   -----------   -------------   ----------   --------   -----------   ---------
<S>                             <C>         <C>       <C>           <C>             <C>          <C>        <C>           <C>
- ----------------------------------------------------------------------------------------------------------------------------------- 
Balance at December 31, 1992    3,830,630   $38,305   $ 7,097,123    $(4,362,246)                   9,195    $ (37,355)  $2,735,827
Proceeds from ESOP                  2,068        21         9,050                                                             9,071
Searle options exercised
 (Note G)                         115,000     1,150       171,350                                                           172,500
Stock options exercised           290,725     2,907       433,113                                                           436,020
Treasury stock (Note J)                                                                            82,644     (355,647)    (355,647)
Private placement (Note K)        633,000     6,330     2,290,353                                                         2,296,683
Net Income                                                             1,172,960                                          1,172,960
- -----------------------------------------------------------------------------------------------------------------------------------
Balance at December 31, 1993    4,871,423    48,713    10,000,989     (3,189,286)      $     0     91,839     (393,002)   6,467,414
- ----------------------------------------------------------------------------------------------------------------------------------- 
Unrealized appreciation on
  marketable securities                                                                 62,843                               62,843
Stock options exercised           143,925     1,439       231,903                                                           233,342
Proceeds from ESOP                  6,000        60        21,680                                                            21,740
Treasury stock (Note J)                                                                            10,000      (52,500)     (52,500)
Net income                                                             1,336,685                                          1,336,685
- ----------------------------------------------------------------------------------------------------------------------------------- 
Balance at December 31, 1994    5,021,348    50,212    10,254,572     (1,852,601)       62,843    101,839     (445,502)   8,069,524
- ----------------------------------------------------------------------------------------------------------------------------------- 
Unrealized Appreciation on
  marketable securities                                                                 20,797                               20,797
Stock options exercised            27,875       280        43,144                                                            43,424
Proceeds from ESOP                  8,980        90        21,634                                                            21,724
Treasury stock (Note J)                                                                             5,180      (9,069)       (9,069)
Net Loss                                                              (2,117,319)                                        (2,117,319)
- ----------------------------------------------------------------------------------------------------------------------------------- 
Balance at December 31, 1995    5,058,203   $50,582   $10,319,350    $(3,969,920)      $83,640    107,019   $(454,571)   $6,029,081
- ----------------------------------------------------------------------------------------------------------------------------------- 
</TABLE>

   The accompanying notes are an integral part of the financial statements.

                                      F-6
<PAGE>
 
A.  SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES:

   1.  CONSOLIDATION

       The consolidated financial statements of the Company include the accounts
       of the Company and its wholly owned subsidiaries, Microfluidics
       Corporation ("MFC") and MediControl Corporation ("MediControl").

       All significant intercompany transactions have been eliminated.

   2.  CASH EQUIVALENTS

       The Company considers securities with maturities of three months or less,
       when purchased, to be cash equivalents.

   3.  MARKETABLE SECURITIES

       During 1994, the Company adopted Statement of Financial Accounting
       Standards No. 115, "Accounting for Certain Investments in Debt and Equity
       Securities" (SFAS 115). The adoption of SFAS 115 resulted in an increase
       in stockholders' equity of $20,797 and $62,843 in 1995 and 1994,
       respectively. In accordance with this statement, prior years' financial
       statements have not been restated to reflect the change in accounting
       method.

       At December 31, 1995 and 1994, marketable equity securities have been
       categorized as available for sale and, as a result, are stated at fair
       value. Unrealized holding gains and losses, net of tax, are included as a
       component of stockholders' equity until realized.

   4.  INVENTORIES

       Inventories are stated at the lower of cost or market. Approximate cost
       is determined on a first-in, first-out basis. Certain inventories are
       held on customer premises on a trial basis preparatory to sale.

                                      F-7
<PAGE>
 
    5.  EQUIPMENT AND LEASEHOLD IMPROVEMENTS

        The Company's equipment and leasehold improvements are recorded at
        cost.  Depreciation is computed on the straight-line method, based
        upon useful lives of three to five years.  Leasehold improvements are
        amortized on the straight-line method based upon the lesser of the
        estimated useful lives or term of the lease.  Expenditures for
        maintenance and repairs are expensed as incurred.  Upon retirement or
        sale of property and equipment, the cost of the disposed asset and the
        related accumulated depreciation are removed from the accounts and any
        resulting gain or loss is credited or charged to operations.

    6.  INTANGIBLES

         Patents, patent applications and rights are stated at acquisition
         cost.  Amortization of patents is recorded using the straight-line
         method over the legal lives of the patents.  The excess of cost over
         fair value of net assets acquired is amortized over 5 years.  The
         Company periodically reviews the carrying value of intangible assets
         and impairments are recognized when the expected future operating cash
         flows derived from such intangible assets is less than their carrying
         value.

     7.  INCOME TAXES

         The Company provides for income taxes based on the provisions of
         Statement of Financial Accounting Standards (SFAS) No. 109,
         "Accounting for Income Taxes," which requires recognition of deferred
         tax assets and liabilities based on the expected future tax
         consequences of events that have been included in the financial
         statements or tax returns.  Under this method, deferred tax assets and
         liabilities are determined based upon the difference between the
         financial statement and tax basis of assets and liabilities using
         enacted tax rates in effect for the year in which the differences are
         expected to be reversed.  Under SFAS No. 109, the effect on deferred
         tax assets and liabilities of a change in tax rates is recognized as
         income or loss in the period that includes the enactment date.

     8.   REVENUE RECOGNITION

          Product sales and related cost of sales are reflected in income when
          goods are shipped for final sale.

     9.   NEW ACCOUNTING PRONOUNCEMENTS

          Statement of Financial Accounting Standards No. 123 "Accounting for
          Stock-Based Compensation" (SFAS 123), will require the Company to
          either elect expense recognition or the disclosure-only alternative
          for stock-based employee compensation.  SFAS 123 must be adopted in
          the Company's 1996 financial

                                      F-8
<PAGE>
 
          statements with comparable disclosures for the prior year.  While the
          Company is reviewing the adoption and impact of SFAS 123, it expects
          to adopt the disclosure only alternative and accordingly this standard
          will have no impact on the Company's results of operations or its
          financial position.

     10.  EARNINGS (LOSS) PER SHARE

          Primary and fully diluted earnings per common and common equivalent
          share are computed by dividing net income by the weighted average
          number of shares of common stock and common stock equivalents
          outstanding during the year.  The calculation of fully diluted income
          (loss) per common share uses a different market price assumption than
          primary earnings (loss) per common share for the reacquisition of
          common shares.

          Net income (loss) per common share is calculated by dividing net
          income (loss) by the weighted average number of shares of common stock
          and common stock equivalents outstanding during the year.  Options and
          warrants are not reflected in the calculation of net income
          (loss) per common share when their inclusion would be anti-dilutive.

     11.  USE OF ESTIMATES

          The process of preparing financial statements in conformity with
          generally accepted accounting principles requires the use of estimates
          and assumptions that affect the reported amounts of assets and
          liabilities at the date of the financial statements and the reported
          amounts of revenues and expenses during the reporting period.  Actual
          results could differ from these estimates.

B.   INDUSTRY SEGMENT AND MAJOR CUSTOMERS:

     The Company has one business segment: the development, manufacture,
     marketing and sale of process and formulation equipment. The Company's
     sales are primarily to companies with processing needs in the chemical,
     pharmaceutical, food, cosmetic, and biotechnology industries.

     Mizuho Industrial Co. (a distributor) accounted for 21% of revenues in
     1995, 20% of revenues in 1994 and 19% of revenues in 1993. Sales in Europe
     were approximately $984,000, $625,000 and $395,000, and sales in Asia were
     approximately $1,514,000, $1,919,000 and $1,892,000 in 1995, 1994 and 1993,
     respectively, of the total revenues. One other customer (PPG) accounted for
     10% of revenues in 1995. A reduction or delay in orders from Mizuho or
     other significant customers could have a material adverse effect on the
     Company's results of operations.

                                      F-9
<PAGE>
 
C.  INVESTMENTS:

    At December 31, 1995 and 1994, the Company held 13,940 and 23,940 shares,
    respectively, of PolyMedica Industries, Inc. at zero cost through its wholly
    owned subsidiary MediControl. The market value of these shares at December
    31, 1995 and 1994 was $83,640 and $104,738, respectively.

    During 1995, the Company sold 10,000 shares of PolyMedica Industries, Inc.
    at a gain of $93,239. On October 28, 1994 the Company received from
    PolyMedica Industries, Inc. a stock dividend of 1,140 shares. During 1993,
    the Company sold 2,000 shares of PolyMedica Industries, Inc. at a gain of
    $34,906.
 
D.  INVENTORY

    The components of inventories at the respective dates are as follows:

<TABLE>
<CAPTION>
                                             December 31,
                                          1995         1994
                                       ----------   ----------
          <S>                          <C>          <C>
 
          Raw materials                $1,530,614   $1,577,841
          Work in process                 418,738      162,532
          Finished goods                  507,037    1,104,316
                                       ----------   ----------
                                       $2,456,389   $2,844,689
                                       ==========   ==========
</TABLE>

E.  INTANGIBLE ASSETS:

    The Company purchased the rights and title of certain liposome and
    microemulsion technology devices from Arthur D. Little in 1985. The
    unamortized license fee and patent are included in intangible assets and are
    being amortized using the straight line method over the useful life of the
    patent, 17 years. Patents and other intangible assets were purchased in 1991
    as a result of a share exchange by MediControl stockholders. These patents
    and other intangible assets are being amortized using the straight line
    method over five years. In addition, the Company capitalized $96,680 of
    patent costs related to the cooperative-venture described in Note M.
    Amortization charged to expense was $53,412 in 1995 and $54,276, in 1994 and
    1993, respectively.

F.   LINE OF CREDIT

    In December 1993, the Company entered into a loan and security agreement
    (the "Agreement") for a line of credit with a local bank. The available line
    or borrowing base is equal to the lesser of $750,000 or 80% of net
    outstanding amount of base accounts, as defined in the agreement.

                                     F-10
<PAGE>
 
    The line is collateralized by all inventory, accounts receivable, general
    intangibles, machinery and equipment and all other property of the Company,
    excluding leased inventory and certain intangible assets. There were no
    borrowings under this line of credit arrangement during 1995 or 1994.

G.   DEBT

    Effective September 30, 1989, the Company issued to G.D. Searle & Company
    ("Searle") a 9% Debenture due September 30, 1994 in the original principal
    amount of $750,000 (the "Searle Debenture"). Interest under the Searle
    Debenture was payable in one installment on the unpaid balance at the due
    date. The Company also granted to Searle an irrevocable, immediately
    exercisable option to purchase up to 600,000 shares of the Company's Common
    Stock at a purchase price of $1.50 per share (the "Searle Option") and
    certain rights to market the Company's products.

    Effective March 9, 1992 and June 30, 1993, Searle exercised the Searle
    Option and purchased 600,000 shares of the Company's Common Stock. Searle
    paid the aggregate exercise price by surrendering the Searle Debenture.

H.  EMPLOYEE BENEFITS:

    Effective January 1, 1990, the Company offered a 401(k) profit-sharing plan
    (the "Plan"), to its employees. All Company and related entity employees who
    are eighteen years of age and have completed one hour of service are
    eligible to participate in the Plan. Employees may contribute from 1% to 20%
    of their compensation. The Company's contribution is discretionary, with
    contributions made from time to time as management deems advisable. The
    Company made no matching contributions during 1995, 1994 or 1993. Plan
    administration expenses of $2,755, $2,110 and $1,660 were incurred by the
    Company in 1995, 1994 and 1993, respectively. The Company instituted a
    cafeteria plan in 1992, giving the employees certain pre-tax advantages on
    specific payroll deductions, at an administrative cost of $500 each in each
    of 1995, 1994 and 1993.

I.  INCOME TAXES

    In 1993, the Company adopted SFAS 109, "Accounting for Income Taxes." The
    cumulative effect of this change of $290,609 was determined at January 1,
    1993, and reported in the Company's prior year financial statement.

                                     F-11
<PAGE>
 
    The provision/(benefit) for income taxes for the current year is as
    follows:

<TABLE>
<CAPTION>
                                       FEDERAL      STATE         TOTAL
<S>                                    <C>         <C>          <C> 
         DECEMBER 31, 1995:
    Current                            $      -    $  6,643     $    6,643
    Deferred                           $939,615    $161,164     $1,100,779
                                       --------    --------    -----------
         Total                         $939,615    $167,807     $1,107,422
                                       ========    ========    ===========
 
         DECEMBER 31, 1994:
    Current                            $      -    $ 14,762     $   14,762
    Deferred                          ($644,656)  ($161,164)   ($  805,820)
                                       --------    --------    -----------
         Total                        ($644,656)  ($146,402)   ($  791,058)
                                       ========    ========    =========== 
</TABLE>

    The current year income tax provision of $6,643 represents state tax. The
    deferred income tax expense of $1,100,779 results from net operating loss
    carryforwards, tax credit carryforwards and other deferred tax assets, which
    may not be realized.

    The approximate tax effect of each type of temporary difference and
    carryforward before and after allocation of the valuation allowance is as
    follows:

<TABLE>
<CAPTION>
                  December 31,                           1995          1994
                                                      ----------    ----------
        <S>                                           <C>           <C>
          Net Operating Loss                          $1,112,967    $  866,721
          Research and Development Credit                174,655       127,347
          Inventory Capitalization                       176,688       186,423
          Other                                           30,437        27,106
          SFAS 115                                       (33,456)      (41,895)
          Depreciation and Amortization                  (17,747)         (458)
                                                      ----------    ----------
 
        Net Deferred Tax Asset Before Valuation        1,443,544     1,165,244
                                                      ----------    ----------
          Valuation Allowance                         (1,443,544)      (60,710)
                                                      ----------    ----------
 
        Net Deferred Tax Asset After Valuation        $        0    $1,104,534
                                                      ==========    ==========
</TABLE>

    The Company has a net operating loss tax carryforward of approximately
    $3,273,000 and research and development tax credit carryforwards of
    approximately $175,000, expiring at various dates beginning in 1999 through
    2010. Ownership changes may result in future limitations on the utilization
    of net operating losses and research and development tax credit
    carryforwards.

                                     F-12
<PAGE>
 
    Based on the financial results known at December 31, 1995, the Company has
    established a complete valuation allowance against the deferred tax asset
    due to the uncertainty of earning sufficient taxable income to realize the
    benefit of these assets. Therefore the Company has increased the valuation
    allowance by $1,382,834 in 1995 to reflect this uncertainty.

    The following schedule reconciles the difference between the federal income
    tax rate and the effective income tax rate:

<TABLE>
<CAPTION>
 
    December 31,                              1995       1994        1993
                                             ------     -------     ------
    <S>                                      <C>        <C>         <C>
 
    Federal Income Tax Rate                   34.0%       34.0%      34.0%
    State Income Tax, Net                        -         6.3%      12.0%
    Permanent Differences                      6.0%        3.2%       4.0%
    Unbenefitted NOL                         (40.0%)         -          -
    Valuation Allowance                      148.0%          -          -
    Recognition of Deferred Tax Assets           -      (188.5%)    (44.0%)
                                             -----      ------      -----
 
    Total Effective Tax Rate                 148.0%     (145.0%)      6.0%
                                             =====      ======      =====
</TABLE>

J.  OPTIONS:

    The Company adopted the 1988 Stock Plan as the successor plan to the 1987
    Stock Plan, which authorizes the grant of Stock Rights for up to 1,750,000
    shares of Common Stock and the 1989 Non-Employee Director Stock Option Plan
    which, as amended at the 1991 shareholders' meeting, authorizes the grant of
    nonqualified stock options for up to 240,000 shares of Common Stock.
    Information concerning stock options are as follows:

                                     F-13
<PAGE>
 
<TABLE>
<CAPTION>
                                                        December 31,
                                               1995         1994         1993
                                            ----------   ----------   ----------
     <S>                                    <C>          <C>          <C>
     Outstanding, at beginning of year         783,150      768,025      975,650
     Option shares:
         Granted                               281,500      178,300      169,500
         Exercised                              27,875      143,925      290,725
         Cancelled                              40,175       19,250       86,400
                                                ------      -------      -------
     Outstanding, at end of year               996,600      783,150      768,025
                                               =======      =======      =======
     Price range of outstanding options
         at year end                        $1.16-7.44   $1.16-7.44   $1.16-6.56
</TABLE>

    There were 495,563 shares of Common Stock subject to exercisable options at
    December 31, 1995, with a price range of $1.16-$7.44. In 1995, options to
    purchase 27,875 shares were exercised at prices ranging from $1.16-$2.32. In
    1994, options to purchase 143,925 shares were exercised at prices ranging
    from $1.16-$4.625 per share. In 1993, options to purchase 290,725 shares
    were exercised at prices ranging from $1.16 to $3.13 per share.

    On January 3, 1995, the Company issued options for an additional 22,500
    shares at a price of $3.88 per share under the 1989 Non-Employee Director
    Stock Plan.

    During 1995, 1994 and 1993, employees delivered shares to the Company in
    payment for shares they were purchasing upon exercise of the stock options
    they held. The aggregate amount of shares received during 1995, 1994, and
    1993 were 5,180, 10,000, and 82,644 shares respectively.

K.  STOCKHOLDER'S EQUITY:

    In 1993, the Company raised additional capital through a private sale of
    633,000 shares of its common stock. The shares were sold at $4.20 per share,
    less expenses of approximately $360,000, resulting in net proceeds to the
    Company of approximately $2,300,000. The financial advisors who facilitated
    the financing were awarded warrants for the purchase of 44,681 shares of
    restricted common stock. The warrants were exercisable from November 5, 1993
    through April 28, 1995 at $6 per share.

                                     F-14
<PAGE>
 
    As partial compensation for financial advisory services rendered to the
    Company by Ladenburg Thalmann & Co., Inc., an investment banking firm
    ("Ladenburg"), the Company on July 15, 1993 granted to Ladenburg a warrant
    to purchase up to 75,000 shares at a per share purchase price of $4.50
    commencing on July 14, 1994 and exercisable until July 14, 1998.

L.  COMMITMENTS AND CONTINGENCIES:

    At December 31, 1995 the Company had an operating lease for the rental of
    its facilities which requires the following minimum payments during the
    following years:

<TABLE>
<CAPTION>
                                   Minimum Payments
                                   ----------------
                    <S>            <C>
                    1996                157,500
                    1997                172,500
                    1998                 90,000
                                       --------
                    Total              $420,000
                                       ========
</TABLE>

    Rent expense for 1995, 1994 and 1993 was approximately $150,000, $162,000
    and 122,000, respectively. The current lease is due to terminate on May 31,
    1998.

M.  COOPERATIVE VENTURE:

    In 1992, the Company formed a cooperative venture with Worcester Polytechnic
    Institute to develop, patent, and license for commercial application the
    Microfluidizer processing technology in certain fields. Expenditures for
    this venture were approximately $48,000 in 1995 and $180,000 in 1994. The
    costs in connection with patent applications of $96,680 have been included
    in intangible assets at December 31, 1995. Amortization began in December,
    1995.

    In September of 1993, the Company signed a license and research and
    development agreement with Catalytica, Inc., as joint licensee, to further
    the studies of the venture with Worcester Polytechnic Institute, as
    licensor. In 1995, the Company spent $247,162 related to this venture, of
    which the Company was reimbursed $118,638 from a government grant awarded
    jointly to Catalytica, Inc. and the Company in relation to this project. The
    remainder of the expenditures were included in research and development
    expense.

N.  SALE OF ASSETS:

    On December 27, 1995, the Company sold to ChemMark Development, Inc.
    ("ChemMark") its business of manufacturing and distributing proprietary
    cosmetic

                                     F-15
<PAGE>
 
    liposomal formulations, sold under the trade name Dermasome/(R)/. In return
    for ChemMark's payment of $50,000, the Company transferred to ChemMark its
    Dermasome/(R)/ trademark, its customer list, its products list, all unfilled
    Dermasome/(R)/ orders, and all products and product literature.
    Additionally, the Company granted to ChemMark a two year, world-wide,
    exclusive license to use the Company's proprietary technology and know-how
    and to manufacture and distribute Dermasome products. In exchange, the
    Company received a one-time, non-refundable $50,000 rights grant acquisition
    fee, and the payment over the license term of a percentage royalty equal to
    ten percent (10%) of the net sales realized by ChemMark on the sale of
    products derived from the Company's technology. Notwithstanding the amount
    of such percentage royalty, ChemMark is obligated to pay a minimum royalty
    payment in the amount of $100,000, payable in 22 equal monthly installments
    of $4,167.67, with a final payment of $8,333.34 due upon the second
    anniversary of the agreement. As security for ChemMark's performance of its
    obligations to the Company, the Company retains a security interest in the
    trademark. The Company recognized a gain of $81,537 upon the sale of the
    Dermasome/(R)/ business.

O.  RELATED PARTY TRANSACTIONS:

    During 1995, 1994 and 1993, the Company and an entity controlled by Mr.
    Gruverman, the Company's Chairman, entered into an arrangement whereby such
    entity reimbursed the Company for a portion of certain administrative
    expenses. The Company was reimbursed approximately $31,155, $21,800 and
    $16,400 by such entity during 1995, 1994 and 1993, respectively. The Company
    reimbursed the entity controlled by Mr. Gruverman $53,478, $32,898 and
    $56,580 for consulting services (other than those of Mr. Gruverman) paid by
    such entity on behalf of the Company in 1995, 1994 and 1993, respectively.

                                     F-16
<PAGE>
 
SIGNATURES

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange
Act of 1934, the Registrant has duly caused this report to be signed on its
behalf by the undersigned thereunto duly authorized, in the city of Newton,
Commonwealth of Massachusetts, on the 26th day of March, 1996.

                                    MICROFLUIDICS INTERNATIONAL CORPORATION


                                    By:  /s/ Michael A. Lento
                                         --------------------
                                         Michael A. Lento
                                         President
<PAGE>
 
Pursuant to the requirements of the Securities and Exchange Act of 1934, this
report has been signed below by the following persons on behalf of the
registrant and in the capacities and on the dates indicated.

<TABLE>
<CAPTION>
Signature                       Title                             Date
- ---------                       -----                             ----
<S>                             <C>                               <C> 
/s/ Irwin J. Gruverman          Chief Executive Officer           March 26, 1996
- --------------------------      (Principal Executive Officer),
Irwin J. Gruverman              Chairman of the Board of
                                Directors and Secretary
 
 
/s/ Michael A. Lento            President and Treasurer           March 26, 1996
- -------------------------       (Principal Financial and
Michael A. Lento                Accounting Officer)
 
  
/s/ Robert L. Bogomolny         Director                          March 26, 1996
- --------------------------
Robert L. Bogomolny
 
 
/s/ Marshall S. Sterman         Director                          March 26, 1996
- --------------------------
Marshall S. Sterman
 
  
/s/ Michael K. Hooker           Director                          March 26, 1996
- --------------------------
Michael K. Hooker


/s/ James N. Little             Director                          March 26, 1996
- ----------------------
James N. Little
</TABLE>
<PAGE>
 
                                 EXHIBIT INDEX

Exhibit
Number    Description of Exhibit
- -------   ----------------------

 3.3(a)   Certificate of Incorporation for the Company, as amended (filed as
          Exhibit 2A to Registration Statement No. 0-11625 on Form 8-A and
          incorporated herein by reference).

 3.3(b)   By-Laws for the Company, as amended (filed as Exhibit 3(b) to
          Registration Statement No. 2-85290 on Form S-1 and Incorporated herein
          by reference).

 3.10(a)  1987 Stock Plan (filed as Exhibit 10(g) to the Company's Annual Report
          on Form 10-K for the fiscal year ended December 31, 1987 and
          incorporated herein by reference).

 3.10(b)  1988 Stock Plan (filed as Exhibit 10(g) to the Company's Annual Report
          on Form 10-K for the fiscal year ended December 31, 1988 and
          incorporated herein by reference).

 3.10(c)  1989 Non-Employee Directors Stock Option Plan (filed as Exhibit 10(h)
          to the Company's Annual Report on Form 10-K for the fiscal year ended
          December 31, 1988 and incorporated herein by reference).

 3.10(d)  Loan Agreement between The First National Bank of Boston and
          Microfluidics International Corporation dated as of December 10, 1993
          (filed as Exhibit 10.1 to Form 8-K filed on December 27, 1993 and
          incorporated herein by reference).

 3.10(e)  Lease for 30 Ossipee Road, Newton, Massachusetts dated April 22, 1993
          between Microfluidics International Corporation and J. Frank Garrity,
          Trustee of 1238 Chestnut Street Trust under Declaration of Trust dated
          May 23, 1969, recorded with Middlesex South Registry of Deeds in Book
          11682, Page 384 (filed as Exhibit 3.10(e) to the Company's Form 10-K
          for the fiscal year ended December 31, 1993 and incorporated herein by
          reference).

 3.10(f)  Letter of Understanding between Microfluidics International
          Corporation and Worcester Polytechnic Institute dated as of April 3,
          1993 (filed as Exhibit 3.10(f) to the Company's Form 10-K for the
          fiscal year ended December 31, 1993 and incorporated herein by
          reference).

 3.10(g)  Agreement between Microfluidics International Corporation and
          Catalytica, Inc. dated as of October 18, 1993 (filed as Exhibit
          3.10(g) to the Company's Form 10-K for the fiscal year ended December
          31, 1993 and incorporated herein by reference).

 3.10(h)  License Agreement among Microfluidics International Corporation,
          Worcester Polytechnic Institute and Catalytica, Inc. dated as of
          October 18, 1993 (filed as Exhibit 3.10(h) to the Company's Form 10-K
          for the fiscal year ended December 31, 1993 and incorporated herein by
          reference).

*3.10(i)  Agreement, dated July 27, 1995, between Microfluidics International
          Corporation and Michael T. Rumley.
<PAGE>
 
Exhibit
Number     Description of Exhibit
- -------    ----------------------

 *3.10(j)  Letter, dated August 16, 1995, from Microfluidics International
           Corporation to Michael T. Rumley.

 *3.10(k)  Letter, dated December 31, 1995, from Microfluidics International
           Corporation to Irwin J. Gruverman.

 *3.10(l)  Warrant for the Purchase of Shares of Common Stock, dated July 15,
           1993, in favor of Ledenburg, Thalmann & Co. Inc.

 *3.21     Subsidiaries of the Registrant.

 *3.24     Consent of Coopers & Lybrand L.L.P.

 *3.27     Financial Data Schedule

_____________________
 *Filed herewith

<PAGE>
 
                                   AGREEMENT
                                   ---------

    It is hereby agreed by and between Michael T. Rumley, hereinafter referred
to as "Mr. Rumley" and Microfluidics International Corporation, together with
its wholly owned subsidiaries, hereinafter jointly referred to as the "Company,"
for good and sufficient consideration more fully described below, that:

    1.  Employment Status.  Effective July 28, 1995 (the "Termination Date"), 
        -----------------
Mr. Rumley resigned from both employment with and/or any officer or director
position(s) he holds or has held for the Company.  As of such Termination Date,
Mr. Rumley's salary ceased and any entitlement he has or might have under any
Company-provided benefit program terminated except as required by federal or
state law or otherwise described below.

    2.  Consideration.
        ------------- 

    (a) Salary Continuation.
        ------------------- 

        1.  For the six-month period from July 29, 1995 through January 28,
1996, the Company shall pay Mr. Rumley a total of Four Thousand Four Hundred and
Sixty Dollars and Fifty Cents ($4,460.50) on a bi-weekly basis, the first such
payment to be made on the first regularly scheduled pay day on or immediately
following the Effective Date of this Agreement, as defined below in Section
8.*

        2. Commencing January 29, 1996, the Company shall pay Mr. Rumley Two
Thousand Nine Hundred and Seventy-Three Dollars and Sixty-Six Cents ($2,973.66)
on a bi-weekly basis until the earlier of July 28, 1996 or the day on which Mr.
Rumley becomes either employed or involved in activities for which he is
remunerated.  If Mr. Rumley becomes employed or involved in activities for which
he is remunerated, Mr. Rumley shall receive Four Hundred and Forty-Six Dollars
and Five Cents ($466.05) on a bi-weekly basis from the date of either such
employment or involvement until July 28, 1996.*

        3.  All payments set forth in this clause (a) of Section 2 shall be
made in accordance with the Company's normal payroll practices and are subject
to applicable (if any) federal, state and/or local withholding, payroll and
other taxes.

    (b) Mr. Rumley shall have the opportunity to purchase the computer/printer
provided to him by the Company for Twelve Hundred Dollars ($1,200), which amount
shall be deducted from any accrued, unused vacation pay to which Mr. Rumley
shall be entitled.  Any remaining accrued, unused vacation pay to which Mr.
Rumley might be entitled shall be paid to him as of the Termination Date.

    (c) The Company shall endeavor to facilitate sale of Mr. Rumley's
exercisable stock options, but in making such endeavor shall not suffer any
negative impact or tax consequences.

- ----------------
*Payments are gross amounts, from which appropriate withholding will be
deducted.
<PAGE>
 
    3.  Settlement of Amounts Due Employee.  The amounts set forth above in
        ----------------------------------                                 
Section 2, together with any amounts previously provided to Mr. Rumley by the
Company, shall be complete and unconditional payment, settlement, satisfaction
and accord with respect to all obligations and liabilities of the Company and
any of its affiliated companies (including their respective successors, assigns,
shareholders, officers, directors, employees and/or agents) to Mr. Rumley, and
all claims, causes of action and damages by Mr. Rumley against the Company
and/or any such other parties regarding Mr. Rumley's employment with and
termination from employment with the Company, including, without limitation, all
claims for back wages, salary, draws, commissions, bonuses, vacation pay,
expenses, compensation, severance pay, attorney's fees, compensatory damages,
exemplary damages, or other costs or sums.

    4.   Confidentiality.  Mr. Rumley agrees not to make any negative or adverse
         ---------------
remarks whatsoever concerning the business, operations, technologies, products,
services, marketing strategies, pricing policies, management affairs and
financial condition of the Company, its affiliated companies and/or their
successors, assigns, shareholders, officers, directors, employees and/or agents.
Mr. Rumley agrees he shall not divulge or publish, directly or indirectly, any
information whatsoever regarding the substance, terms or existence of this
Agreement and/or any discussions or negotiations relating to this Agreement to
any person or organization, except to him immediate family members, counsel or
accountant.

     5.  Release.
         ------- 

     (a) In exchange for the amounts and actions described in Section 2 and
other good and valuable consideration, receipt of which is hereby acknowledged,
Mr. Rumley and his representatives, agents, estate, successors and assigns,
absolutely and unconditionally hereby release and forever discharge the Company,
its affiliated companies and/or their successors, assigns, directors,
shareholders, officers, employees and/or agents, both individually and in their
official capacities, from any and all actions or causes of action, suits,
claims, complaints, contracts, liabilities, agreements, promises, debts and
damages, whether existing or contingent, known or unknown, which arise out of
Mr. Rumley's employment with or termination from the Company.  This release is
intended by Mr. Rumley to be all encompassing and to act as a full and total
release of any claims that Mr. Mr. Rumley may have or has had against the
Company, its affiliated companies and/or their successors, assigns, directors,
shareholders, officers, employees and/or agents, both individually and in their
official capacity with the Company, including, but not limited to, any federal,
state or local law or regulation dealing with either employment or employment
discrimination such as those laws or regulations concerning discrimination on
the basis of age, race, color, religion, creed, sex, sexual orientation,
national origin, ancestry, marital status, physical or mental disability, or
status as a disabled or military veteran; any contract, whether oral or written,
express or implied; or common law.

     (b) Mr. Rumley agrees not only to release and discharge the Company, its
affiliated companies and/or their respective successors, assigns, shareholders,
officers, directors, employees and/or agents from any and all claims as stated
above that Mr. Rumley could make on his own behalf or on behalf of others, but
also those claims which might be made by any other person or organization on
behalf of Mr. Rumley, and Mr. Rumley specifically waives any right to become,
and promises not to become, a member of any class in a case in which a claim or
claims against the Company, its affiliated companies and/or their respective
successors, assigns, shareholders, officers, directors, employees and/or agents
are made involving any matters which arise out of Mr. Rumley's employment with
or termination from employment with the Company.  Mr. Rumley agrees that the
Company has made the payment(s)

                                       2
<PAGE>
 
specified in Section 2, the Company will have satisfied any and all legal and/or
contractual obligations to him.  Nothing in this Agreement is to be construed as
an admission by the Company, its affiliated companies and/or their respective
successors, assigns, shareholders, officers, directors, employees and/or agents
of any liability of unlawful conduct whatsoever.

     6.  Waiver of Rights and Claims Under the Age Discrimination and
         ------------------------------------------------------------
Employment Act of 1967.
- ---------------------- 

     (a) Mr. Rumley has been informed that since he is 40 years of age or older,
he has or might have specific rights and/or claims under the Age Discrimination
and Employment Act of 1967.  In consideration for the amounts described in
Section 2 hereof, which are in excess of anything to which Mr. Rumley already is
entitled, Mr. Rumley specifically waives such rights and/or claims to the extent
that such rights and/or claims arose prior to the date this Agreement was
executed.

     (b) Mr. Rumley was advised by the Company of his right to consult with an
attorney prior to executing this Agreement.

     (c) Mr. Rumley was further advised when he was presented by the Company
with the original draft of this Agreement on July 27, 1995, that he had at least
21 days within which to consider its terms and to consult with or seek advice
from an attorney or any other person of his choosing, until the close of
business on August 17, 1995.

     7.  Representations and Governing Law.
         --------------------------------- 

     (a) This Agreement represents the complete and sole understanding between
the parties, supersedes any and all other agreements and understandings, whether
oral or written.  This agreement may not be modified, altered or rescinded
except upon written consent of the Company and Mr. Rumley.  The invalidity or
unenforceability of any provision of this Agreement shall not affect the other
provisions of this Agreement, but this Agreement shall be revised, construed and
reformed to the fullest extent possible to effectuate the purposes of this
Agreement.  This Agreement shall be binding upon and inure to the benefit of the
Company and Mr. Rumley and their respective heirs, successors and assigns.

     (b) This Agreement shall be governed by and construed in accordance with
the laws of the Commonwealth of Massachusetts, without giving effect to the
principles of conflicts of law thereof.

     (c) Mr. Rumley represents that he has read the foregoing Agreement, fully
understands the terms and conditions of such Agreement, and is voluntarily
executing the same.  In entering into this Agreement, Mr. Rumley does not rely
on any representation, promise or inducement made by the Company, with the
exception of the consideration described in this document.

                                       3
<PAGE>
 
     8.  Effective Date.  Mr. Rumley may revoke this Agreement during the
         --------------                                                  
period of seven (7) days following its execution by Mr. Rumley, until the close
of business on August 3, 1995, and this Agreement shall not become effective or
enforceable until this revocation period has expired.

     Executed this 27th day of July, 1995.


                                    /s/ Michael T. Rumley
                                    ---------------------
                                    Michael T. Rumley

                                    MICROFLUIDICS INTERNATIONAL CORPORATION


                                    By:  /s/ Irwin J. Gruverman
                                         ----------------------

                                    Title:  Chief Executive Officer
                                            -----------------------

                                       4
<PAGE>
 
                           [TO BE KEPT SEPARATE FROM
                               AGREEMENT/WAIVER]


     Michael Rumley acknowledges that he was informed and understands that he
has at least 21 days within which to consider the attached Agreement/Waiver, has
consulted with an attorney regarding such Agreement and has considered carefully
every provision of the Agreement, and that after having engaged in those
actions, prefers to and has requested that he enter into the Agreement/Waiver
prior to the expiration of the 21-day period.



Dated:  7/27/95                     /s/ Michael T. Rumley
        -------                     ---------------------
                                    Michael T. Rumley


                                    Witness: /s/ Jack M. Swig
                                             ----------------


                                    MICROFLUIDICS INTERNATIONAL CORPORATION



Dated:  7/27/95                     By: /s/ Irwin J. Gruverman
        -------                         ----------------------
                                        Its Chief Executive Officer

                                       5

<PAGE>
 
                    MICROFLUIDICS INTERNATIONAL CORPORATION
                                30 Ossipee Road
                               Newton, Ma  02164

Dear Michael:

     You have asked for an explanation of your employment status under the
Agreement you executed on July 27, 1995, which became effective seven (7) days
later on August 3, 1995.  You believe that Sections 1 and 2(c) of the Agreement
are inconsistent and create confusion about your employment status for the
period July 29, 1995 through January 28, 1996.

     We have reviewed the Agreement and do not agree that there is any
inconsistency.  However, we are willing to interpret the Agreement so that your
employment terminates on January 28, 1996, and that you gave us (6) months
notice of such termination on July 28, 1995.  Your resignation from your office
or director positions remains effective as of July 28, 1995.

     For the period from July 29, 1995 through January 28, 1996, you will be
considered an employee on special assignment.  As a result, you will be eligible
for certain specific benefits offered by the Company, 401(k) participation,
stock options and life insurance.  You will not be eligible for vacation accrual
or any other benefits, since you will be involved only on special assignments.

     I trust this letter clarifies any question you might have under the
Agreement which you executed on July 27, 1995 and which became effective on
August 3, 1995.  If so, I suggest that you execute this letter in the area
provided below and that the original of this letter be attached to the original
of the Agreement and made a part thereof.  To the extent there is any
inconsistency between this document and the letter, the letter shall take
precedence.

                                    Microfluidics International Corporation



                                    /s/ Irwin J. Gruverman
                                    ----------------------
                                    Irwin J. Gruverman, CEO



/s/ Michael T. Rumley
- ---------------------
Michael T. Rumley

Date:  8/16/95
       -------

<PAGE>
 
                    MICROFLUIDICS INTERNATIONAL CORPORATION
                                30 Ossipee Road
                               Newton, Ma  02164



December 31, 1995



Irwin J. Gruverman
16 Tanglewood Road
Needham, MA  02194

Dear Mr. Gruverman:

This will confirm our Agreement concerning your compensation as Chairman and CEO
of MFIC, and charges you will incur in connection with your activities for G & G
Diagnostics Corporation.

You may maintain an office in our premises at 30 Ossipee Road and will pay MFIC
$800.00 per month for space, incidental administrative support, minor supplies
usage, and limited use of telephone and copying resources.  You will reimburse
MFIC for express charges, outside accounting help and materials and services
purchased through our system.

Subject to approval by the Board, we will pay you at a rate of $72,000 per year,
beginning January 1, 1996.  Of that amount, 1/3 will be paid in restricted MFIC
stock, at a price of $1.50/share, at this time.  The balance will be paid in
cash, in 4 equal increments, at the beginning of each quarter.  A bonus of up to
$28,000 will be paid, contingent on meeting performance goals to be agreed.  You
agree that MFIC will withhold money from your compensation to pay appropriate
taxes.  You will be included in MFIC's insurance and medical programs as in past
years, at no cost to you, as part of your compensation.

Jack Swig will be an employee of MFIC.  He will be available to G & G on a half-
time basis, and G & G will reimburse 50% of his salary fringes and tax costs to
MFIC on a quarterly basis.

MICROFLUIDICS INTERNATIONAL, INC.



/s/ Michael Lento                        /s/ Irwin Gruverman
- ---------------------------              ------------------------------------
Michael Lento, President                 Irwin Gruverman
                                         Individually and as President of G&G
                                         Diagnostics Corporation

/s/ Irwin Gruverman
- -------------------
Irwin Gruverman, CEO

<PAGE>
 
               WARRANT FOR THE PURCHASE OF SHARES OF COMMON STOCK

No. 75,000                                                                Shares
    ------        

          FOR VALUE RECEIVED, Microfluidics International Corporation (the
"Company"), a Delaware corporation, hereby certifies that Ladenburg, Thalmann &
Co. Inc., or its permitted assigns are entitled to purchase from the Company, at
any time or from time to time commencing July 15, 1994, and prior to 5:00 P.M.,
New York City time then current, on July 14, 1998, 75,000 fully paid and non-
assessable shares of the common stock, $0.01 par value, of the Company at the
purchase price of $337,500 (computed on the basis of $4.50 per share).
(Hereinafter, (i) said common stock, together with any other equity securities
which may be issued by the Company with respect thereto or in substitution
therefor, is referred to as the "Common Stock," (ii) the shares of the Common
Stock purchasable hereunder are referred to as the "Warrant Shares," (iii) the
aggregate purchase price payable hereunder for the Warrant Shares is referred to
as the "Aggregate Warrant Price," (iv) the price payable hereunder for each of
the shares of the Warrant Shares is referred to as the "Per Share Warrant Price"
and (v) this warrant and all warrants hereafter issued in exchange or
substitution for this warrant are referred to as (the "Warrants").  The
Aggregate Warrant Price is not subject to adjustment.  The Per Share Warrant
Price is subject to adjustment as hereinafter provided; in the event of any such
adjustment, the number of Warrant Shares shall be adjusted by dividing the
Aggregate Warrant Price by the Per Share Warrant Price in effect immediately
after such adjustment.

1.   EXERCISE OF WARRANT.
     ------------------- 

     (a) This Warrant may be exercised, in whole at any time or in part from
     time to time, commencing July 15, 1994 (the "Commencement Date"), and prior
     to 5:00 P.M., New York City time then current, on July 14, 1998, (the
     "Expiration Date"), by the holder of this Warrant (the "Holder") by the
     surrender of this Warrant (with the subscription form at the end hereof
     duly executed) at the address set forth in Subsection 9(a) hereof, together
     with proper payment of the Aggregate Warrant Price, or the proportionate
     part thereof if this Warrant is exercised in part.  Payment for the Warrant
     Shares shall be made by certified or official bank check, payable to the
     order of the Company.  If this Warrant is exercised in part, this Warrant
     must be exercised for a number of whole shares of the Common Stock, and the
     Holder is entitled to received a new Warrant covering the number of Warrant
     Shares in respect of which this Warrant has not been exercised and setting
     forth the proportionate part of the Aggregate Warrant Price applicable to
     such Warrant Shares.  Upon such exercise and surrender of this Warrant, the
     Company will (i) issue a certificate or certificates in the name of the
     Holder for the largest number of whole shares of the Common Stock to which
     the Holder shall be entitled and, if this Warrant is exercised in whole, in
     lieu of any fractional share of the Common Stock to which the Holder shall
     be entitled, pay cash equal to the fair value of such fractional share
     (determined in such reasonable manner as the Board of Directors of the
     Company shall determine), and (ii) deliver the other securities and
     properties receivable upon the exercise of this Warrant, or the
     proportionate part thereof if this Warrant is exercised in part, pursuant
     to the provisions of this Warrant.

     (b) In lieu of exercising this Warrant in the manner set forth in paragraph
     1(a) above, this Warrant may be exercised between the Commencement Date and
     the Expiration Date by surrender of the Warrant without payment of any
     other consideration, commission or remuneration, together with the cashless
     exercise subscription form at the end hereof, duly
<PAGE>
 
     executed.  The number of shares to be issued in exchange for the Warrant
     shall be the product of (x) the excess of the market price of the Common
                                     ---------                               
     Stock on the date of surrender of the Warrant and the exercise subscription
     form over the Per Share Warrant Price and (y) the number of shares subject
          ----                                                                 
     to issuance upon exercise of the Warrant, divided by the market price of
     the Common Stock on such date.  Upon such exercise and surrender of this
     Warrant, the Company will (i) issue a certificate or certificates in the
     name of the Holder for the largest number of whole shares of the Common
     Stock to which the Holder shall be entitled and, in lieu of any fractional
     share of the Common Stock to which the Holder shall be entitled, pay cash
     equal to the fair value of such fractional share (determined in such
     reasonable manner as the Board of Directors of the Company shall
     determine), and (ii) deliver the other securities and properties receivable
     upon the  exercise of this Warrant, pursuant to the provisions of this
     Warrant.

2.   RESERVATION OF WARRANT SHARES.
     ----------------------------- 

     The Company agrees that, prior to the expiration of this Warrant, the
     Company will at all times have authorized and in reserve, and will keep
     available, solely for issuance or delivery upon the exercise of this
     Warrant, such number of shares of the Common Stock and such amount of other
     securities and properties as from time to time shall be deliverable to the
     Holder upon the exercise of this Warrant, free and clear of all
     restrictions on sale or transfer (except such as may be imposed under
     applicable Federal and State securities laws) and free and clear of all
     preemptive rights and all other rights to purchase securities of the
     Company.

3.   PROTECTION AGAINST DILUTION.
     --------------------------- 

     (a) If, at any time or from time to time after the date of this Warrant,
     the Company shall distribute to the holders of its outstanding Common
     Stock, (i) securities, other than shares of Common Stock, or (ii) property,
     other than cash, without payment therefor, with respect to Common Stock,
     then, and in each such case, the Holder, upon the exercise of this Warrant,
     shall be entitled to receive the securities and property which the Holder
     would hold on the date of such exercise if, on the date of this Warrant,
     the Holder had been the holder of record of the number of shares of the
     Common Stock subscribed for upon such exercise and, during the period from
     the date of this Warrant to and including the date of such exercise, had
     retained such shares and the securities and properties receivable by the
     Holder during such period.  Notice of each such distribution shall be
     forthwith mailed to the Holder.

     (b) If, at any time or from time to time after the date of this Warrant,
     the Company shall (i) pay a dividend (excluding a cash dividend) or make a
     distribution on its capital stock in shares of Common Stock, (ii) subdivide
     its outstanding shares of Common Stock into a greater number of shares,
     (iii) combine its outstanding shares of Common Stock into a smaller number
     of shares or (iv) issue by reclassification of its Common Stock any shares
     of capital stock of the Company, the Per Share Warrant Price in effect
     immediately prior to such action shall be adjusted so that the Holder of
     any Warrant thereafter exercised shall be entitled to receive the number of
     shares of Common Stock or other capital stock of the Company which he would
     have owned or been entitled to received immediately following the happening
     of any of the events described above had such Warrant been exercised
     immediately prior thereto.  An adjustment made pursuant to this (b) shall
     become effective immediately after the record date in the case of a
     dividend or distribution and shall become effective immediately after the
     effective date in the case of a subdivision, combination or
     reclassification.  If, as a result of an adjustment made pursuant to

                                       2
<PAGE>
 
     this (b), the holder of any Warrant thereafter surrendered for exercise
     shall become entitled to receive shares of two or more classes of capital
     stock or shares of Common Stock and other capital stock of the Company, the
     Board of Directors (whose determination shall be conclusive and shall be
     described in a written notice to the Holder of any Warrant promptly after
     such adjustment) shall determine the allocation of the adjusted Per Share
     Warrant Price between or among shares of such classes or capital stock or
     shares of Common Stock and other capital stock.

     (c) Except as provided in 3(e), in case the Company shall hereafter issue
     or sell any shares of Common Stock for a consideration per share less than
     the Per Share Warrant Price in effect immediately prior to such issuance or
     sale, the Per Share Warrant Price shall be adjusted as of the date of such
     issuance or sale so that the same shall equal the price determined by
     dividing (i) the sum of (A) the number of shares of Common Stock
     outstanding immediately prior to such issuance or sale multiplied by the
     Per Share Warrant Price plus (B) the consideration received by the Company
     upon such issuance or sale by (ii) the total number of shares of Common
     Stock outstanding after such issuance or sale.

     (d) Except as provided in 3(e), in case the Company shall hereafter issue
     or sell any rights, options, warrants or securities convertible into Common
     Stock entitling the holders thereof to purchase the Common Stock or to
     convert such securities into Common Stock at a price per share determined
     by dividing (i) the total amount, if any, received or receivable by the
     Company in consideration of the issuance or sale of such rights, options,
     warrants or convertible securities plus the total consideration, if any,
     payable to the Company upon exercise or conversion thereof (the "Total
     Consideration") by (ii) the number of additional shares of Common Stock
     issuable upon exercise or conversion of such securities less than the then
     Per Share Warrant Price in effect on the date of such issuance or sale, the
     Per Share Warrant Price shall be adjusted as of the date of such issuance
     or sale so that the same shall equal the price determined by dividing (i)
     the sum of (A) the number of shares of Common Stock outstanding on the date
     of such issuance or sale multiplied by the Per Share Warrant Price plus (B)
     the Total Consideration by (ii) the number of shares of Common Stock
     outstanding on the date of such issuance or sale plus the maximum number of
     additional shares of Common Stock issuable upon exercise or conversion of
     such securities.

     (e) No adjustment in the Per Share Warrant Price shall be required in the
     case of (i) the issuance of up to 395,226 shares of Common Stock upon the
     exercise of options which may be granted under the Company's Stock Option
     Plans as in effect on the date hereof, (ii) the issuance of shares pursuant
     to the exercise of this Warrant or (iii) the sale of up 850,000 shares of
     common stock pursuant to a Reg S prior to August 31, 1993.

     (f) In case of any consolidation or merger to which the Company is a party
     other than a merger or consolidation in which the Company is the continuing
     corporation, or in case of any sale or conveyance to another entity of the
     property of the Company as an entirety or substantially as an entirety, or
     in the case of any statutory exchange of securities with another entity
     (including any exchange effected in connection with a merger of any other
     corporation with the Company), the Holder of this Warrant shall have the
     right thereafter to convert such Warrant into the kind and amount of
     securities, cash or other property which he would have owned or have been
     entitled to receive immediately after such consolidation, merger, statutory
     exchange, sale or conveyance had this Warrant been exercised immediately
     prior to the effective date of such consolidation, merger, statutory
     exchange, sale or conveyance and in any such case, if

                                       3
<PAGE>
 
     necessary, appropriate adjustment shall be made in the application of the
     provisions set forth in this Section 3 with respect to the rights and
     interests thereafter of the Holder of this Warrant to the end that the
     provisions set forth in this Section 3 shall thereafter correspondingly be
     made applicable, as nearly as may reasonably be, in relation to any shares
     of stock or other securities or property thereafter deliverable on the
     exercise of this Warrant.  The above provisions of this 3(f) shall
     similarly apply to successive consolidations, mergers, statutory exchanges,
     sales or conveyances.  Notice of any such consolidation, merger, statutory
     exchange, sale or conveyance, and of said provisions so proposed to be
     made, shall be mailed to the Holder not less than 20 days prior to such
     event.  A sale of all or substantially all of the assets of the Company for
     a consideration consisting primarily of securities shall be deemed a
     consolidation or merger for the foregoing purposes.

     (g) No adjustment in the Per Share Warrant Price shall be required unless
     such adjustment would require an increase or decrease of at least $0.05 per
     share of Common Stock; provided, however, that any adjustments which by
                            --------  -------                               
     reason of this (g) are not required to be made shall be carried forward and
     taken into account in any subsequent adjustment; and provided further,
                                                      --- -------- ------- 
     however, that adjustments shall be required and made in accordance with the
     provisions of this Section 3 (other than this (g)) not later than such time
     as may be required in order to preserve the tax-free nature of a
     distribution to the Holder of this Warrant or Common Stock.  All
     calculations under this Section 3 shall be made to the nearest cent or to
     the nearest 1/100th of a share, as the case may be.  Anything in this
     Section 3 to the contrary notwithstanding, the Company shall be entitled to
     make such reductions in the Per Share Warrant Price, in addition to those
     required by this Section 3, as it in its discretion shall deem to be
     advisable in order that any stock dividend, subdivision of shares or
     distribution of rights to purchase stock or securities convertible or
     exchangeable for stock hereafter made by the Company to its shareholders
     shall not be taxable.

     (h) Whenever the Per Share Warrant Price is adjusted as provided in this
     Section 3 and upon any modification of the rights of the Holder of this
     Warrant in accordance with this Section 3, the Company shall, at its own
     expense, within ten (10) days of such adjustment or modification, deliver
     to the holder of this Warrant a certificate of the Principal Financial
     Officer of the Company setting forth the Per Share Warrant Price and the
     number of Warrant Shares after such adjustment or the effect of such
     modification, a brief statement of the facts requiring such adjustment or
     modification and the manner of computing the same.  In addition, within
     thirty (30) days of the end of the Company's fiscal year next following any
     such adjustment or modification, the Company shall, at its own expense,
     deliver to the Holder of this Warrant a certificate of a firm of
     independent public accountants of recognized standing selected by the Board
     of Directors (who may be the regular auditors of the Company) setting forth
     the same information as required by such Principal Financial Officer
     Certificate.

     (i) If the Board of Directors of the Company shall declare any dividend or
     other distribution in cash with respect to the Common Stock, other than out
     of earned surplus, the Company shall mail notice thereof to the Holder not
     less than 10 days prior to the record date fixed for determining
     shareholders entitled to participate in such dividend or other
     distribution.

                                       4
<PAGE>
 
4.   FULLY PAID STOCK; TAXES.
     ----------------------- 

     The Company agrees that the shares of the Common Stock represented by each
     and every certificate for Warrant Shares delivered on the exercise of this
     Warrant in accordance with the terms hereof shall, at the time of such
     delivery, be validly issued and outstanding, fully paid and non-assessable,
     and not subject to preemptive rights, or other contractual rights to
     purchase securities of the Company, and the Company will take all such
     actions as may be necessary to assure that the par value or stated value,
     if any, per share of the Common Stock is at all times equal to or less than
     the then Per Share Warrant Price.  The Company further covenants and agrees
     that it will pay, when due and payable, any and all Federal and state
     stamp, original issue or similar taxes which may be payable in respect of
     the issue of any Warrant Share or certificate therefor.

5.   REGISTRATION UNDER SECURITIES ACT OF 1933.
     ----------------------------------------- 

     (a) The Company agrees that if, at any time during the period commencing on
     July 15, 1994 and ending on July 14, 1998, the Holder and/or the Holders of
     any other Warrants and/or Warrant Shares who or which shall hold not less
     than 50% of the Warrants and/or Warrant Shares outstanding at such time and
     not previously sold pursuant to this Section 5, request that the Company
     file a registration statement under the Securities Act of 1933 (the "Act")
     covering all or any of the Warrant Shares, the Company will (i) promptly
     notify the Holder and all other registered holders, if any, of other
     Warrant and/or Warrant Shares that such registration statement will be
     filed and that the Warrant Shares which are then held, and/or which may be
     acquired upon the exercise of Warrants, by the Holder and such holders will
     be included in such registration statement at the Holder's and such
     Holders' request, (ii) cause such registration statement to cover all
     Warrant Shares which it has been so requested to include, (iii) use its
     best efforts to cause such registration statement to become effective as
     soon as practicable and to remain effective and current and (iv) take all
     other action necessary under any Federal or state law or regulation of any
     governmental authority to permit all Warrant Shares which it has been so
     requested to include in such registration statement to be sold or otherwise
     disposed of and will maintain such compliance with each such Federal and
     state law and regulation of any governmental authority for the period
     necessary for the Holder and such Holders to effect the proposed sale or
     other disposition.

     (b) The Company agrees that if, at any time and, from time to time during
     the period commencing on July 15, 1994 and ending on July 14, 2000, the
     Board of Directors of the Company shall authorize the filing of a
     registration statement (any such registration statement being sometimes
     hereinafter called a "Subsequent Registration Statement") under the Act
     (otherwise than pursuant to 5(a) hereof) in connection with the proposed
     offer of any of its securities by it or any of its shareholders, the
     Company will (i) promptly notify the Holder and all other registered
     Holders, if any, of other Warrants and/or Warrant Shares that such
     Subsequent Registration Statement will be filed and that the Warrant Shares
     which are then held, and/or which may be acquired upon the exercise of the
     Warrants, by the Holder and such Holders will be included in such
     Subsequent Registration Statement at the Holder's and such Holders'
     request, (ii) cause such Subsequent Registration Statement to cover all
     Warrant Shares which it has been so requested to include, (iii) cause such
     Subsequent Registration Statement to become effective as soon as
     practicable and to remain effective and current and (iv) take all other
     action necessary under any Federal or state law or regulation of any
     governmental authority to permit

                                       5
<PAGE>
 
     all Warrant Shares which it has been so requested to include in such
     Subsequent Registration Statement to be sold or otherwise disposed of and
     will maintain such compliance with each such Federal and state law and
     regulation of any governmental authority for the period necessary for the
     Holder and such Holders to effect the proposed sale or other disposition.

     (c) Whenever the Company is required pursuant to the provisions of this
     Section 5 to include Warrant Shares in a registration statement, the
     Company shall (i) furnish each Holder of any such Warrant Shares and each
     underwriter of such Warrant Shares with such copies of the prospectus,
     including the preliminary prospectus, conforming to the Act (and such other
     documents as each such Holder or each such underwriter may reasonably
     request) in order to facilitate the sale or distribution of the Warrant
     Shares, (ii) use its best efforts to register or qualify such Warrant
     Shares under the blue sky laws (to the extent applicable) of such
     jurisdiction or jurisdictions as the Holders of any such Warrant Shares and
     each underwriter of Warrant Shares being sold by such Holders shall
     reasonably request and (iii) take such other actions as may be reasonably
     necessary or advisable to enable such Holders and such underwriters to
     consummate the sale or distribution in such jurisdiction or jurisdictions
     in which such Holders shall have reasonably requested that the Warrant
     Shares be sold.

     (d) The Company shall pay all expenses incurred in connection with any
     registration or other action pursuant to the provisions of this Section,
     including the attorneys' fees and expenses of the holder(s) of the Warrant
     Shares covered by such registration incurred in connection with such
     registration or other action, other than underwriting discounts and
     applicable transfer taxes relating to the Warrant Shares.

     (e) The market price of Common Stock shall mean the price of a share of
     Common Stock on the relevant date, determined on the basis of the last
     reported sale price of the Common Stock as reported on the NASDAQ National
     Market System ("NASDAQ") or, if there is no such reported sale on the day
     in question, on the basis of the average of the closing bid and asked
     quotations as so reported, or, if the Common Stock is not listed on NASDAQ,
     the last reported sale price of the Common Stock on such other national
     securities exchange upon which the Common Stock is listed, or, if the
     Common Stock is not listed on any national securities exchange, on the
     basis of the average of the closing bid and asked quotations on the day in
     question in the over-the-counter market as reported by the National
     Association of Securities Dealers' Automated Quotations System, or if not
     so quoted, as reported by National Quotation Bureau, Incorporated, or
     similar organization.

6.   INDEMNIFICATION.
     --------------- 

     (a) The Company agrees to indemnify and hold harmless each selling holder
     of Warrant Shares and each person who controls any such selling holder
     within the meaning of Section 15 of the Act, and each and all of them, from
     and against any and all losses, claims, damages, liabilities or actions,
     joint or several, to which any selling holder of Warrant Shares or they or
     any of them may become subject under the Act or otherwise and to reimburse
     the persons indemnified as above for any legal or other expenses (including
     the cost of any investigation and preparation) incurred by them in
     connection with any litigation or threatened litigation, whether or not
     resulting in any liability, but only insofar as such losses, claims,
     damages, liabilities or actions arise out of, or are based upon, (i) any
     untrue statement or alleged untrue statement of a material fact contained
     in any registration statement pursuant to which Warrant Shares were

                                       6
<PAGE>
 
     registered under the Act (hereinafter called a "Registration Statement"),
     any preliminary prospectus, the final prospectus or any amendment or
     supplement thereto (or in any application or document filed in connection
     therewith) or document executed by the Company based upon written
     information furnished by or on behalf of the Company filed in any
     jurisdiction in order to register or qualify the Warrant Shares under the
     securities laws thereof or the omission or alleged omission to state
     therein a material fact required to be stated therein or necessary to make
     the statements therein, in the light of the circumstances under which they
     were made, not misleading, or (ii) the employment by the Company of any
     device, scheme or artifice to defraud, or the engaging by the Company in
     any act, practice or course of business which operates or would operate as
     a fraud or deceit, or any conspiracy with respect thereto, in which the
     Company shall participate, in connection with the issuance and sale of any
     of the Warrant Shares; provided, however, that (i) the indemnity agreement
                            --------  -------                                  
     contained in this (a) shall not extend to any selling holder of Warrant
     Shares in respect of any such losses, claims, damages, liabilities or
     actions arising out of, or based upon, any such untrue statement or alleged
     untrue statement, or an such omission or alleged omission, of such
     statement or omission was based upon and made in conformity with
     information furnished in writing to the Company by a selling holder of
     Warrant Shares specifically for use in connection with the preparation of
     such Registration Statement, any final prospectus, any preliminary
     prospectus or any such amendment or supplement thereto.  The Company agrees
     to pay any legal and other expenses for which it is liable under this (a)
     from time to time (but not more frequently than monthly) within 30 days
     after its receipt of a bill therefor.

     (b) Each selling holder of Warrant Shares, severally and not jointly, will
     indemnify and hold harmless the Company, its directors, its officers who
     shall have signed the Registration Statement and each person, if any, who
     controls the Company within the meaning of Section 15 of the Act to the
     same extent as the foregoing indemnity from the Company, but in each case
     to the extent, and only to the extent, that any statement in or omission
     from or alleged omission from such Registration Statement, any final
     prospectus, any preliminary prospectus or any amendment or supplement
     thereto was made in reliance upon information furnished in writing to the
     Company by such selling holder specifically for use in connection with the
     preparation of the Registration Statement, any final prospectus or the
     preliminary prospectus or any such amendment or supplement thereto;
                                                                        
     provided, however, that the obligation of any holder of Warrant Shares to
     --------  -------                                                        
     indemnify the Company under the provisions of this (b) shall be limited to
     the product of the number of Warrant Shares being sold by the selling
     holder and the market price of the Common Stock on the date of the sale to
     the public of these Warrant Shares.  Each selling holder of Warrant Shares
     agrees to pay any legal and other expenses for which it is liable under
     this (b) from time to time (but not more frequently than monthly) within 30
     days after receipt of a bill therefor.

     (c) If any action is brought against a person entitled to indemnification
     pursuant to the foregoing s (a) or (b) (an "indemnified party") in respect
     of which indemnity may be sought against a person granting indemnification
     (an "indemnifying party") pursuant to such s, such indemnified party shall
     promptly notify such indemnifying party in writing of the commencement
     thereof; but the omission so to notify the indemnifying party of any such
     action shall not release the indemnifying party from any liability it may
     have to such indemnified party otherwise than on account of the indemnity
     agreement contained in (a) or (b) of this Section 6.  In case any such
     action is brought against an indemnified party and it notifies an
     indemnifying party of the commencement thereof, the indemnifying party
     against which a claim is to be made will be

                                       7
<PAGE>
 
     entitled to participate therein at its own expense and, to the extent that
     it may wish, to assume at its own expense the defense thereof, with counsel
     reasonably satisfactory to such indemnified party; provided, however, that
                                                        --------  -------      
     (i) if the defendants in any such action include both the indemnified party
     and the indemnifying party and the indemnified party shall have reasonably
     concluded based upon advice of counsel that there may be legal defenses
     available to it and/or other indemnified parties which are different from
     or additional to those available to the indemnified party, the indemnified
     party shall have the right to select separate counsel to assume such legal
     defenses and otherwise to participate in the defense of such action on
     behalf of such indemnified party or parties and (ii) in any event, the
     indemnified party shall be entitled to have counsel chosen by such
     indemnified party participate in, but not conduct, the defense at the
     expense of the indemnifying party.  Upon receipt of notice from the
     indemnifying party to such indemnified party of its election so to assume
     the defense of such action and approval by the indemnified party of
     counsel, the indemnifying party will not be liable to such indemnified
     party under this Section 6 for any legal or other expenses subsequently
     incurred by such indemnified party in connection with the defense thereof
     unless (i) the indemnified party shall have employed such counsel in
     connection with the assumption of legal defenses in accordance with proviso
     (i) to the next preceding sentence (it being understood, however, that the
     indemnifying party shall not be liable for the expenses of more than one
     separate counsel), (ii) the indemnifying party shall not have employed
     counsel reasonably satisfactory to the indemnified party to represent the
     indemnified party within a reasonable time after notice of commencement of
     the action or (iii) the indemnifying party has authorized the employment of
     counsel for the indemnified party at the expense of the indemnifying party.
     An indemnifying party shall not be liable for any settlement of any action
     or proceeding effected without its written consent.

     (d) In order to provide for just an equitable contribution in circumstances
     in which the indemnity agreement provided for in (a) of this Section 6 is
     unavailable to a selling holder of Warrant Shares in accordance with its
     terms, the Company and the selling holder of Warrant Shares shall
     contribute to the aggregate losses, claims, damages and liabilities, of the
     nature contemplated by said indemnity agreement, incurred by the Company
     and the selling holder of Warrant Shares, in such proportions as is
     appropriate to reflect the relative benefits received by the Company and
     the selling holder of Warrant Shares from any offering of the Warrant
     Shares; provided, however, that if such allocation is not permitted by
             --------  -------                                             
     applicable law or if the indemnified party failed to give the notice
     required under (c) of this Section 6, then the relative fault of the
     Company and the selling holder of Warrant Shares in connection with the
     statements or omissions which resulted in such losses, claims, damages and
     liabilities and other relevant equitable considerations will be considered
     together with such relative benefits.

     (e) The respective indemnity and contribution agreements by the Company and
     the selling holder of Warrant Shares in s (a), (b), (c) and (d) of this
     Section 6 shall remain operative and in full force and effect regardless of
     (i) any investigation made by any selling holder of Warrant Shares or by or
     on behalf of any person who controls such selling holder or by the Company
     or any controlling person of the Company or any director or any officer of
     the company, (ii) payment for any of the Warrant Shares or (iii) any
     termination of this Agreement, and shall survive the delivery of the
     Warrant Shares, and any successor of the Company, or of any selling holder
     of Warrant Shares, or of any person who controls the Company or of any
     selling holder of Warrant Shares, as the case may be, shall be entitled to
     the benefit of such respective indemnity and contribution agreements.  The
     respective indemnity and contribution agreements by the Company and the
     selling holder of Warrant Shares contained in s (a), (b), (c) and (d) of

                                       8
<PAGE>
 
     this Section 6 shall be in addition to any liability which the Company and
     the selling holder of Warrant Shares may otherwise have.

7.   LIMITED TRANSFERABILITY.
     ----------------------- 

     (a) This Warrant is not transferable or assignable by the Holder except (i)
     to Ladenburg, Thalmann & Co. Inc., any successor firm or corporation of
     Ladenburg, Thalmann & Co. Inc., (ii) to any of the officers or employees of
     Ladenburg, Thalmann & Co. Inc. or of any such successor firm or (iii) in
     the case of an individual, pursuant to such individual's last will and
     testament or the laws of descent and distribution and is so transferable
     only upon the books of the Company which it shall cause to be maintained
     for the purpose.  The Company may treat the registered holder of this
     Warrant as he or it appears on the Company's books at any time as the
     Holder for all purposes.  The Company shall permit any holder of a Warrant
     or his duly authorized attorney, upon written request during ordinary
     business hours, to inspect and copy or make extracts from its books showing
     the registered holders of Warrants.  All Warrants will be dated the same
     date as this Warrant.

     (b) By acceptance hereof, the Holder represents and warrants that this
     Warrant is being acquired, and all Warrant Shares to be purchased upon the
     exercise of this Warrant will be acquired, by the Holder solely for the
     account of such Holder and not with a view to the fractionalization and
     distribution thereof and will not be sold or transferred except in
     accordance with the applicable provisions of the Act and the rules and
     regulations of the Securities and Exchange Commission promulgated
     thereunder, and the Holder agrees that neither this Warrant nor any of the
     Warrant Shares may be sold or transferred except under cover of a
     Registration Statement under the Act which is effective and current with
     respect to such Warrant Shares or pursuant to an opinion, in form and
     substance reasonably acceptable to the Company's counsel, that registration
     under the Act is not required in connection with such sale or transfer.
     Any Warrant Shares issued upon exercise of this Warrant shall bear the
     following legend:

          "The Securities represented by this certificate have not been
          registered under the Securities Act of 1933 and are restricted
          securities within the meaning thereof.  Such securities may not be
          sold or transferred except pursuant to a Registration Statement under
          such Act which is effective and current with respect to such
          securities or pursuant to an opinion of counsel reasonably
          satisfactory to the issuer of such securities that such sale or
          transfer is exempt from the registration requirements of such Act."

8.   LOSS, ETC., OF WARRANT.
     ---------------------- 

     Upon receipt of evidence satisfactory to the Company of the loss, theft,
     destruction or mutilation of this Warrant, and of indemnity reasonably
     satisfactory to the Company, if lost, stolen or destroyed, and upon
     surrender and cancellation of this Warrant, if mutilated, and upon
     reimbursement of the Company's reasonable incidental expenses, the Company
     shall execute and deliver to the Holder a new Warrant of like date, tenor
     and denomination.

                                       9
<PAGE>
 
9.   WARRANT HOLDER NOT SHAREHOLDERS.
     ------------------------------- 

     Except as otherwise provided herein, this Warrant does not confer upon the
     Holder any right to vote or to consent to or receive notice as a
     shareholder of the Company, as such, in respect of any matters whatsoever,
     or any other rights or liabilities as a shareholder, prior to the exercise
     hereof.

10.  COMMUNICATION.
     ------------- 

     No notice or other communication under this Warrant shall be effective
     unless, but any notice or other communication shall be effective and shall
     be deemed to have been given if, the same is in writing and is mailed by
     first-class mail, postage prepaid, addressed to:

          (a) the Company at 30 Ossipee Road, Newton, MA 02164 or such other
     address as the Company has designated in writing to the Holder; or

          (b) the Holder at c/o Howard L. Blum, Jr., 540 Madison Avenue, New
     York, NY 10022, or such other address as the Holder has designated in
     writing to the Company.

11.  HEADINGS.
     -------- 

     The headings of this Warrant have been inserted as a matter of convenience
     and shall not affect the construction hereof.

12.  APPLICABLE LAW.
     -------------- 

     This Warrant shall be governed by and construed in accordance with the law
     of the State of New York without giving effect to the principles of
     conflicts of law thereof.

IN WITNESS WHEREOF, the Company has caused this Warrant to be signed by its
Chairman of the Board and its corporate seal to be hereunto affixed and attested
by its Secretary this 15th day of July, 1993.



ATTEST:/s/ Jack M. Swig
       ----------------

                              Microfluidics International Corporation



/s/ Irwin J. Gruverman        By: /s/ Irwin J. Gruverman
- ----------------------            ----------------------
Secretary                         Chairman of the Board



[Corporate Seal]

                                       10
<PAGE>
 
                                  SUBSCRIPTION
                                  ------------

     The undersigned, ______________________________________, pursuant to the
provisions of the foregoing Warrant, hereby agree to subscribe for and purchase
____________________ shares of the Common Stock of_____________________________
covered by said Warrant, and makes payment therefor in full at the price per
share provided by said Warrant.


Dated: ________________________   Signature:___________________________________

                                  Address:_____________________________________


                 SUBSCRIPTION FOR CASHLESS WARRANT SUBSCRIPTION
                 ----------------------------------------------

     The undersigned, ________________________________________, pursuant to the
provisions of the foregoing Warrant, hereby agree to subscribe to that number of
shares of the Common Stock as are issuable in accordance with the formula set
forth in paragraph 1(b) of the Warrant, and makes payment therefor in full by
surrender and delivery of this Warrant.



Dated: ________________________   Signature:___________________________________

                                  Address:_____________________________________


                                   ASSIGNMENT
                                   ----------


     FOR VALUE RECEIVED __________________________ hereby sells, assigns and
transfers unto _________________________________ the foregoing Warrant and all
rights evidenced thereby, and does irrevocably constitute and appoint
____________________________, attorney, to transfer said Warrant on the books of
________________________.



Dated: ________________________   Signature:___________________________________

                                  Address:_____________________________________

                                       11
<PAGE>
 
                               PARTIAL ASSIGNMENT
                               ------------------


     FOR VALUE RECEIVED _________________________________________________ hereby
assigns and transfers unto _________________________________________________ the
right to purchase _________ shares of the Common Stock of Microfluidics
International Corporation by the foregoing Warrant, and a proportionate part of
said Warrant and the rights evidenced hereby, and does irrevocably constitute
and appoint _____________________________________________, attorney, to transfer
that part of said Warrant on the books of __________________________________.


Dated: ________________________   Signature:___________________________________

                                  Address:_____________________________________

                                       12

<PAGE>
 
                                  SUBSIDIARIES
                                  ------------


               Microfluidics Corporation, a Delaware Corporation

               MediControl Corporation, a Delaware Corporation

<PAGE>
 
                       CONSENT OF INDEPENDENT ACCOUNTANTS
                       ----------------------------------


     We consent to the incorporation by reference in the registration statements
of Microfluidics International Corporation on Forms S-8 (File Nos. 33-3242, 33-
6300, 33-19372 and 33-38928) of our report dated February 23, 1996, on our
audits of the consolidated financial statements of Microfluidics International
Corporation as of December 31, 1995 and 1994, and for the years ended December
31, 1995, 1994 and 1993, which report is included in this Annual Report on Form
10-K.



                                                        COOPERS & LYBRAND L.L.P.



Boston, Massachusetts
March 29, 1996

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 5
       
<S>                             <C>
<PERIOD-TYPE>                   YEAR
<FISCAL-YEAR-END>                          DEC-31-1995
<PERIOD-START>                             JAN-01-1995
<PERIOD-END>                               DEC-31-1995
<CASH>                                       1,903,418
<SECURITIES>                                    83,640
<RECEIVABLES>                                1,751,199
<ALLOWANCES>                                         0
<INVENTORY>                                  2,456,389
<CURRENT-ASSETS>                             6,286,619
<PP&E>                                         632,306
<DEPRECIATION>                                 254,971
<TOTAL-ASSETS>                               6,715,986
<CURRENT-LIABILITIES>                          686,905
<BONDS>                                              0
                                0
                                          0
<COMMON>                                        50,582
<OTHER-SE>                                           0
<TOTAL-LIABILITY-AND-EQUITY>                 6,715,986
<SALES>                                              0
<TOTAL-REVENUES>                             5,273,399
<CGS>                                        2,813,801
<TOTAL-COSTS>                                6,556,747
<OTHER-EXPENSES>                                     0
<LOSS-PROVISION>                           (1,009,897)
<INTEREST-EXPENSE>                                   0
<INCOME-PRETAX>                            (1,009,897)
<INCOME-TAX>                                 1,107,422
<INCOME-CONTINUING>                        (2,117,319)
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                               (2,117,319)
<EPS-PRIMARY>                                   (0.43)
<EPS-DILUTED>                                   (0.43)
        

</TABLE>


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