<PAGE>
File No. 2-85454
497(e)
MANULIFE SERIES FUND, INC.
Supplement to Prospectus Dated May 1, 1995
This Supplement updates certain information in the Prospectus.
Please read it and keep it with your Prospectus for future
reference.
<TABLE>
<CAPTION>
Business Experience During Past
Fund Manager(s) Fund Five Years
<S> <C> <C>
Mark A. Schmeer Emerging Growth Investment Management, U.S.
(since 1995) Equity Fund Equities, The Manufacturers Life
Balanced Assets Insurance Company - 1995-present;
Fund Vice President, Sun Life
Common Stock Fund Investment Management - 1993-1995;
Real Estate Manager, U.S. Investments, Ontario
Securities Fund Hydro Corporation - - 1986-1996
Robert Lutzko Emerging Growth Investment Management, U.S.
since 1995) Equity Fund Equities, The Manufacturers Life
Insurance Company - 1995-present;
U.S. Investment Manager, Workers
Compensation Board, Toronto -
1989-1995
Catherine Addison Balanced Assets Investment Management, U.S. Fixed
(since 1988) Fund Income, The Manufacturers Life
Capital Growth Insurance Company, 1985-present
Bond Fund
Emily Shum Money-Market Fund Investment Management, Money-
(since 1992) Market, The Manufacturers Life
Insurance Company, 1992-present;
Money Market Manager, ManuVest
Investment Management Corporation,
1985-1991
Stephen Hill International Investment Management, The
(since 1995) Fund Manufactures Life Insurance
Pacific Rim Company, 1995-present; Director,
Emerging Markets Invesco Asset Management, 1993-
Fund 1994; Consultant, 1993; Director,
Yasuda Trust Europe, 1989-1992
Mark Andrew Hirst International Investment Management, The
(since 1994) Fund Manufactures Life Insurance
Company, 1986-present
</TABLE>
<PAGE>
MANULIFE SERIES FUND, INC.
Supplement to Prospectus Dated May 1, 1995 (continued)
<TABLE>
<CAPTION>
Business Experience During Past
Fund Manager(s) Fund Five Years
<S> <C> <C>
Richard James International Investment Management, The
Crook Fund Manufactures Life Insurance
(since 1994) Pacific Rim Company, 1975-present
Emerging Markets
Fund
Emilia Panadero International Investment Management, The
Perez Fund Manufactures Life Insurance
(since 1995) Pacific Rim Company, 1989-present
Emerging Markets
Fund
Leslie Grober Real Estate Investment Management, U.S.
(since 1995) Securities Fund Equities, The Manufacturers Life
Insurance Company - 1994-present;
Investment Representative,
Toronto-Dominion Bank - 1991-1993;
Banking, Bank of Montreal 1990-
1991
Rhonda Chang Common Stock Fund Investment Management, The
(since 1995) Manufacturers Life Insurance
Company - 1994-present; Investment
Analyst, American International
Group - 1990-1994
</TABLE>
The date of this Supplement is January 1, 1996.
