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497(e)
File No. 2-85454
MANULIFE SERIES FUND, INC.
Supplement to Statement of Additional Information
for Prospectus for Manulife Series Fund, Inc.
Dated May 1, 1995
This supplement updates certain information in the Prospectus.
Please read it and keep it with your Prospectus for future
reference.
On December 27, 1995, the Manager, Manufacturers Adviser
Corporation, became a wholly-owned subsidiary of The
Manufacturers Life Insurance Company of America. Both the
Manager and The Manufacturers Life Insurance Company of
America are indirect wholly-owned subsidiaries of The
Manufacturers Life Insurance Company.
The date of this Supplement is December 27, 1995.