FIRST TRUST OF INSURED MUNICIPAL BONDS SERIES 106
485BPOS, 1997-09-30
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      File No. 2-85574


               SECURITIES AND EXCHANGE COMMISSION
                   WASHINGTON, D.C. 20549-1004
                                
                         POST-EFFECTIVE
                        AMENDMENT NO. 14
                                
                               TO
                                
                            FORM S-6

For Registration Under the Securities Act of 1933 of Securities
of Unit Investment Trusts Registered on Form N-8B-2


     THE FIRST TRUST OF INSURED MUNICIPAL BONDS, SERIES 106
                      (Exact Name of Trust)
                                
                      NIKE SECURITIES L.P.
                    (Exact Name of Depositor)
                                
                      1001 Warrenville Road
                     Lisle, Illinois  60532
                                
  (Complete address of Depositor's principal executive offices)
                                


      NIKE SECURITIES L.P.         CHAPMAN AND CUTLER
      Attn:  James A. Bowen        Attn:  Eric F. Fess
      1001 Warrenville Road        111 West Monroe Street
      Lisle, Illinois  60532       Chicago, Illinois  60603


        (Name and complete address of agents for service)
It is proposed that this filing will become effective (check
appropriate box)

:____:    immediately upon filing pursuant to paragraph (b)
:__X_:    September 30, 1997
:____:    60 days after filing pursuant to paragraph (a)
:____:    on (date) pursuant to paragraph (a) of rule (485 or
486)
Pursuant to Rule 24f-2 under the Investment Company Act of  1940,
the issuer has registered an indefinite amount of securities.   A
24f-2 Notice for the offering was last filed on July 21, 1997.
                                
                                
              CONTENTS OF POST-EFFECTIVE AMENDMENT
                    OF REGISTRATION STATEMENT
This Post-Effective Amendment of Registration Statement comprises
the following papers and documents:

      The facing sheet

      The purpose of the Amendment

      The signatures

      The Consent of Independent Auditors

      Financial Data Schedule
                                
                                
                                
                                
                  THE PURPOSE OF THE AMENDMENT
The  purpose  of  this amendment is to terminate the  declaration
made  pursuant  to  Rule 24f-2 promulgated under  the  Investment
Company Act of 1940, as amended, because Units of The First Trust
of  Insured  Municipal  Bonds, Series 106  are  no  longer  being
offered  for  sale in the secondary market.  A final  Rule  24f-2
Notice  with  respect to such series has been filed  concurrently
with this filing.
                                
                           SIGNATURES
Pursuant  to the requirements of the Securities Act of 1933,  the
Registrant,  The First Trust of Insured Municipal  Bonds,  Series
106,  certifies  that  it  meets  all  of  the  requirements  for
effectiveness  of  this Registration Statement pursuant  to  Rule
485(b) under the Securities Act of 1933 and has duly caused  this
Post-Effective  Amendment  of its Registration  Statement  to  be
signed on its behalf by the undersigned thereunto duly authorized
in  the  Village of Lisle and State of Illinois on September  30,
1997.

THE FIRST TRUST OF INSURED MUNICIPAL BONDS, SERIES 106
                                                      (Registrant)
                                By    NIKE SECURITIES L.P.
                                                      (Depositor)


                                By    Robert M. Porcellino
                                      Vice President

Pursuant to the requirements of the Securities Act of 1933,  this
Post-Effective  Amendment  of  Registration  Statement  has  been
signed  below by the following person in the capacity and on  the
date indicated:

Signature                  Title*                  Date

Robert D. Van Kampen    Director of       )
                   Nike Securities        )
                   Corporation, the       )
                   General Partner        ) September 30, 1997
                   of Nike Securities L.P.)
                                          )
David J. Allen          Director of       )
                     Nike Securities      )Robert M. Porcellino
            Corporation, the General      )Attorney-in-Fact**
                     Partner of Nike
                      Securities L.P.

*      The  title  of  the  person named  herein  represents  his
capacity  in  and  relationship  to  Nike  Securities  L.P.,  the
Depositor.

**    An executed copy of the related power of attorney was filed
with  the  Securities and Exchange Commission in connection  with
Amendment  No.  1 to Form S-6 of The First Trust Combined  Series
258  (File  No.  33-63483) and the same  is  hereby  incorporated
herein by this reference.


                  CONSENT OF INDEPENDENT AUDITORS
                                
We  consent  to  the  reference to our  firm  under  the  caption
"Experts" and to the use of our report dated August 29,  1997  in
this  Post-Effective Amendment to the Registration Statement  and
related Prospectus of The First Trust of Insured Municipal  Bonds
dated September 25, 1997.



                                  ERNST & YOUNG LLP




Chicago, Illinois
September 24, 1997
                                



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