CYTOGEN CORP
10-C, 1995-03-08
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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<PAGE>
 
                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                   FORM 10-C

                REPORT BY ISSUER OF SECURITIES QUOTED ON NASDAQ

                          INTERDEALER QUOTATION SYSTEM

                  FILED PURSUANT TO SECTION 13 OR 15(D) OF THE
                SECURITIES EXCHANGE ACT OF 1934 AND RULE 13A-17
                              OR 15D-17 THEREUNDER

                               CYTOGEN CORPORATION
                 ----------------------------------------------
                 (Exact name of issuer as specified in charter)

        600 College Road East, CN 5308, Princeton, New Jersey 08540-5308
        ----------------------------------------------------------------
                    (Address of principal executive offices)

Issuer's telephone number, including area code   (609) 987-8200
                                               ---------------------------------

                   I.  CHANGE IN NUMBER OF SHARES OUTSTANDING

  Indicate any change (increase or decrease) of 5% or more in the number of
shares outstanding:
 
1.     Title of Security  Common Stock, $0.01 par value per share
- - --------------------------------------------------------------------------------
2.     Number of shares outstanding before the change  25,831,016
- - --------------------------------------------------------------------------------
3.     Number of shares outstanding after the change 31,453,714
- - --------------------------------------------------------------------------------
4.     Effective date of change  February 27, 1995
- - --------------------------------------------------------------------------------
5.     Method of change:

  Specify method (such as merger, acquisition, exchange, distribution, stock
split, reverse split, acquisition of stock for treasury, etc.)

                                  Acquisition
- - --------------------------------------------------------------------------------

  Give brief description of transaction    Issuance of Common Stock pursuant to
- - --------------------------------------------------------------------------------
Exchange Offer for Units, each Unit consisting of 1.0 share of Callable Common
- - --------------------------------------------------------------------------------
Stock of CytoRad Incorporated and 1.0 warrant to acquire 1.0 share of Common
- - --------------------------------------------------------------------------------
Stock of Cytogen Corporation
- - --------------------------------------------------------------------------------

                         II.  CHANGE IN NAME OF ISSUER

1.     Name prior to change
- - --------------------------------------------------------------------------------
2.     Name after change
- - --------------------------------------------------------------------------------
3.     Effective date of charter amendment changing name
- - --------------------------------------------------------------------------------
4.     Date of shareholder approval of change, if required
- - --------------------------------------------------------------------------------

Date March 8, 1995                      /s/ T. Jerome Madison
- - --------------------------------------------------------------------------------
                                        (Officer's signature & title)
                                        Name:   T. Jerome Madison
                                        Title:  Vice President, Chief Financial
                                                Officer and Secretary


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