CEL SCI CORP
S-3/A, 2000-06-09
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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As filed with the Securities and Exchange Commission on June ____, 2000.

                                                       Registration No 333-34604

                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM S-3

                                 AMENDMENT NO. 1

                             Registration Statement
                                      Under
                           THE SECURITIES ACT OF 1933

                               CEL-SCI Corporation
                  ------------------------------------------
               (Exact name of registrant as specified in charter)

                                    Colorado
                            -----------------------
                 (State or other jurisdiction of incorporation)

                                                      8229 Boone Blvd. #802
                                                     Vienna, Virginia  22182
          84-09l6344                                    (703) 506-9460
-------------------------------                     ---------------------------
    (IRS Employer I.D. Number)                 (Address, including zip code, and
                                              telephone number including area of
                                                   principal executive offices)

                                  Geert Kersten
                              8229 Boone Blvd. #802
                             Vienna, Virginia 22182
                                 (703) 506-9460
                   --------------------------------------------
          (Name and address, including zip code, and telephone number,
                   including area code, of agent for service)

         Copies of all communications, including all communications sent
                  to the agent for service, should be sent to:

                              William T. Hart, Esq.
                                  Hart & Trinen
                             1624 Washington Street
                             Denver, Colorado 80203
                                 (303) 839-0061

        APPROXIMATE DATE OF COMMENCEMENT OF PROPOSED SALE TO THE PUBLIC:
                 As soon as practicable after the effective date
                         of this Registration Statement

If the only securities  being registered on this Form are being offered pursuant
to dividend or interest reinvestment plans, please check the following box. [ ]

The prospectus which forms a part of this registration statement also relates to
the securities registered by means of a prior registration statement on Form S-3
(Commission File # 333-94675).

<PAGE>


If any of the  securities  being  registered on this Form are to be offered on a
delayed or continuous  basis  pursuant to Rule 415 under the  Securities  Act of
1933, other than securities offered only in connection with dividend or interest
reinvestment plans, check the following box. [X]

If this Form is filed to register additional securities for an offering pursuant
to Rule 462(b) under the Securities Act, please check the following box and list
the  Securities  Act  registration  statement  number of the  earlier  effective
registration for the same offering.
[  ]

If this Form is a  post-effective  amendment filed pursuant to Rule 462(c) under
the  Securities  Act,  check  the  following  box and  list the  Securities  Act
registration  statement number of the earlier effective  registration  statement
for the same offering. [ ]

If delivery  of the  prospectus  is  expected  to be made  pursuant to Rule 434,
please check the following box. [ ]

                           CALCULATION OF REGISTRATION FEE
Title of each                          Proposed       Proposed
 Class of                              Maximum        Maximum
Securities              Securities     Offering       Aggregate    Amount of
  to be                  to be         Price Per      Offering   Registration
Registered             Registered      Unit (1)        Price         Fee
---------              ----------     -----------    ----------    --------

Common stock (2)         1,026,666        $3.00    $3,079,998        $814
Common stock (3)           413,344        $3.00     1,240,032         328
Common stock (4)         3,000,000        $3.00     9,000,000       2,376
                         ---------                  ---------     -------

Total                    4,440,010 (5)            $13,320,030      $3,518
                         =============            ===========      ======



(1) Offering price computed in accordance with Rule 457(c).
(2)   Shares of common stock to be sold by the selling shareholders.
(3) Shares of common stock issuable upon the exercise of Series C Warrants.  The
    Series C  Warrants  were  issued in  connection  with the sale of  CEL-SCI's
    common stock to the selling  shareholders.  Includes additional shares which
    may be issued due to potential adjustments to Warrant exercise price.
(4) Shares of common  stock which may be issuable  upon the exercise of Series D
    Warrants. The Series D Warrants were also issued in connection with the sale
    of CEL-SCI's common stock to the selling shareholders.  The actual number of
    shares  issuable  upon the  exercise of the Series D warrants  (if any) will
    vary  depending  upon a  number  of  factors,  including  the  price  of the
    Company's common stock at certain dates.
(5) The  prospectus  which  forms  a part of this  registration  statement  also
    relates to 2,374,000 shares of common stock  previously  registered by means
    of a registration  statement on Form S-3 (Commission File # 94675). A filing
    fee of $1,818 was paid when this prior registration statement was filed.

      Pursuant  to  Rule  416,  this   Registration   Statement   includes  such
indeterminate  number of  additional  securities as may be required for issuance

<PAGE>

upon the exercise of the warrants as a result of any adjustment in the number of
securities  issuable by reason of the  anti-dilution  provisions of the Series A
Warrants, the Series B Warrants and/or the Sales Agent's Warrants.

      The registrant hereby amends this  Registration  Statement on such date or
dates as may be necessary to delay its effective date until the registrant shall
file a further  amendment  which  specifically  states  that  this  Registration
Statement shall  thereafter  become effective in accordance with Section 8(a) of
the  Securities  Act of l933 or until the  Registration  Statement  shall become
effective on such date as the Commission,  acting pursuant to said Section 8(a),
may determine.



<PAGE>


PROSPECTUS
                               CEL-SCI CORPORATION
                                  Common Stock

      By means of this prospectus  certain  shareholders of CEL-SCI  Corporation
are offering to sell up to 6,769,000  shares of CEL-SCI's  common  stock,  which
amount  includes  shares of common stock which may be issuable upon the exercise
of  Cel-Sci's  Series B and  Series D  warrants.  The  actual  number  of shares
issuable  upon the  exercise of the Series B and Series D warrants (if any) will
vary depending upon a number of factors, including the price of CEL-SCI's common
stock at certain dates. However, based upon the market price of Cel-Sci's common
stock as of the date of this prospectus,  Cel-Sci would not be required to issue
any shares upon the  exercise of the Series B warrants  and would be required to
issued 1,540,000 shares upon the exercise of the Series D warrants. Accordingly,
as of May 31, 2000 the selling shareholders would only be able to sell 3,981,409
shares of CEL-SCI's common stock.

    The securities offered by this prospectus are speculative and involve a high
degree of risk and should be  purchased  only by persons  who can afford to lose
their entire investment. Prospective investors should consider certain important
factors described under "Risk Factors" beginning on page 7 of this prospectus.

    These Securities Have Not Been Approved or Disapproved by the Securities and
Exchange  Commission Nor Has the Commission Passed Upon the Accuracy or Adequacy
of this Prospectus. Any Representation to the Contrary is a Criminal Offense.

    CEL-SCI's common stock is traded on the American Stock Exchange.  On May 31,
2000 the closing price of CEL-SCI's  common stock on the American Stock Exchange
was $3.00.






                  The date of this prospectus is June ___, 2000



<PAGE>


PROSPECTUS SUMMARY

      THIS SUMMARY IS QUALIFIED IN ITS ENTIRETY BY THE MORE DETAILED INFORMATION
APPEARING ELSEWHERE IN THIS PROSPECTUS.



CEL-SCI

      CEL-SCI Corporation was formed as a Colorado  corporation in 1983. CEL-SCI
is involved in the  research  and  development  of certain  drugs and  vaccines.
CEL-SCI  manufactures  MULTIKINE,  its first, and main product,  using CEL-SCI's
proprietary  cell  culture  technologies,   which  involve  a  combination,   or
"cocktail",   of  natural  human   interleukin-2  and  certain  lymphokines  and
cytokines.  CEL-SCI is testing  MULTIKINE  to  determine  if it is  effective in
improving the immune response of cancer patients.  CEL-SCI is testing its second
most   advanced   product,   HPG-30W,   to  determine  if  it  is  an  effective
vaccine/treatment  against  the AIDS  virus.  The third  technology  CEL-SCI  is
developing,  Ligand Epitope Antigen  Presentation  System  (LEAPS),  is a T-cell
modulation  technology  which  health  care  professionals  can use to  direct a
specific  immune  response  in persons  vaccinated  with  HGP-30W and to develop
potential  treatments and/or vaccines against various  diseases.  Present target
diseases are AIDS, herpes simplex,  malaria,  tuberculosis,  prostate cancer and
breast cancer.

      Before  human  testing  can begin  with  respect  to a drug or  biological
product, preclinical studies are conducted in laboratory animals to evaluate the
potential efficacy and the safety of a product. Human clinical studies generally
involve  a  three-phase  process.  The  initial  clinical  evaluation,  Phase I,
consists of administering  the product and testing for safe and tolerable dosage
levels.  Phase II trials  continue the  evaluation  of safety and  determine the
appropriate dosage for the product,  identify possible side effects and risks in
a larger group of subjects,  and provide  preliminary  indications  of efficacy.
Phase III trials  consist of testing  for  actual  clinical  efficacy  within an
expanded group of patients at geographically dispersed test sites.

      CEL-SCI has funded the costs  associated with the clinical trials relating
to CEL-SCI's  technologies,  research expenditures and CEL-SCI's  administrative
expenses with the public and private  sales of shares of CEL-SCI's  common stock
and borrowings from third parties, including affiliates of CEL-SCI.

      CEL-SCI does not expect to develop commercial  products for several years,
if at  all.  CEL-SCI  has had  operating  losses  since  its  inception,  had an
accumulated  deficit  of  approximately  $(57,190,000)  at March 31,  2000,  and
expects to incur substantial losses for the foreseeable future.

      CEL-SCI's executive offices are located at 8229 Boone Blvd., #802, Vienna,
Virginia 22182, and its telephone number is (703) 506-9460.



<PAGE>


THE OFFERING

Securities Offered:

      By means of this prospectus  certain CEL-SCI  shareholders are offering to
sell up to 4,026,399  shares of the common stock of CEL-SCI.  CEL-SCI  refers to
the owners of these shares as the selling shareholders in this prospectus.

Common                      Stock  Outstanding:  As of May 31, 2000, CEL-SCI had
                            20,439,209   shares  of  common   stock  issued  and
                            outstanding.  The number of outstanding  shares does
                            not give  effect to shares  which may be issued upon
                            the exercise and/or conversion of options,  warrants
                            or other convertible  securities held by the selling
                            shareholders  or  other  persons.  See  "Comparative
                            Share Data".

Risk                        Factors:  The purchase of the securities  offered by
                            this prospectus involves a high degree of risk. Risk
                            factors  include the lack of revenues and history of
                            loss,  need for additional  capital and need for FDA
                            approval.  See the "Risk  Factors"  section  of this
                            prospectus for additional Risk Factors.

AMEX Symbol:                CVM

Summary Financial Data

                                Six Months Ended      Years Ended September 30,
                                                      -------------------------
                                  March 31, 2000        1999           1998
                              ---------------------     ----           ----
                                  (Unaudited)
                                   ---------
Investment Income and
  Other Revenues                  $135,848          $  469,518     $  792,994

Expenses:
  Research and Development       2,487,290           4,461,051      3,833,854

Depreciation and Amortization      143,337             268,210        295,331

General and Administrative       2,067,469           3,230,982      3,106,492
                                 ---------         -----------   ------------

Net Loss                        (4,562,248)        $(7,490,725)   $(6,442,683)
                                ===========        ============   ============

Accretion of Preferred Stock            --                  --      1,980,000

Preferred Stock Dividends               --                  --             --
                         -----------------  ---------------------------------

Net Loss attributable to
common stock holders           $(4,562,248)        $(7,490,725)   $(8,422,683)
                               ============        ============   ============

Loss per common share (basic)$         (0.25)   $        (0.52)$         (0.74)
                             ================   ===============================

<PAGE>


Loss per common share (diluted)$         (0.25) $        (0.52)$         (.74)
                               ================ ==============================

Weighted average
  common shares
  outstanding                      18,071,192         14,484,352    11,379,437

Balance Sheet Data
                                  March 31,                September 30,
                              -----------------      ------------------------
                                 2000                 1999           1998
                                 ----                 ----           ----

Working Capital              $15,864,508          $6,152,715    $12,926,014
Total Assets                  17,395,329           7,559,772     14,431,813
Current Liabilities              566,850             433,265        427,147
Long Term and Other Liabilities   28,321              28,321         29,382
Total Liabilities                595,171             461,586        456,529
Shareholders' Equity                              16,800,158      7,098,186
13,975,284

                                  RISK FACTORS

      Investors  should be aware  that this  offering  involves  certain  risks,
including those described below, which could adversely affect the value of their
holdings of common stock. CEL-SCI does not make, nor has it authorized any other
person to make,  any  representation  about the future market value of CEL-SCI's
common stock. In addition to the other information contained in this prospectus,
the following factors should be considered carefully in evaluating an investment
in the Shares offered by this prospectus

CEL-SCI Has Earned Only Limited Revenues and Has a History of Losses.
--------------------------------------------------------------------

      CEL-SCI has had only limited  revenues since it was formed in 1983.  Since
the date of its formation and through March 31, 2000 CEL-SCI incurred net losses
of approximately $(57,190,000).  During the years ended September 30, 1997, 1998
and 1999 CEL-SCI suffered losses of $(8,189,458),  $(6,442,683) and $(7,490,725)
respectively.  CEL-SCI has relied  principally  upon the  proceeds of public and
private sales of securities to finance its  activities to date. All of CEL-SCI's
potential  products are in the early stages of  development,  and any commercial
sale of these products will be many years away. Accordingly,  CEL-SCI expects to
incur substantial losses for the foreseeable future.

      There can be no assurance CEL-SCI will be profitable. At the present time,
CEL-SCI  intends  to  use  available  funds  to  finance  CEL-SCI's  operations.
Accordingly, while payment of dividends rests within the discretion of the Board
of Directors,  no common stock  dividends have been declared or paid by CEL-SCI.
CEL-SCI does not presently intend to pay dividends on its common stock and there
can be no assurance that common stock dividends will ever be paid.



<PAGE>


If  Cel-Sci  cannot  obtain  additional  capital,  Cel-Sci  may have to delay or
postpone  development and research  expenditures  which may influence  Cel-Sci's
ability to produce a timely and competitive product.

      Clinical and other studies  necessary to obtain approval of a new drug can
be time  consuming  and costly,  especially  in the United  States,  but also in
foreign countries.  The different steps necessary to obtain regulatory approval,
especially that of the Food and Drug  Administration,  involve significant costs
and may require  several  years to complete.  CEL-SCI  expects that it will need
additional  financing over an extended period of time in order to fund the costs
of future clinical  trials,  related  research,  and general and  administrative
expenses.  There  can be no  assurance  that  CEL-SCI  will be  able  to  obtain
additional funding from other sources.

If Cost Estimates for Clinical  Trials and Research Are Inaccurate  CEL-SCI Will
Require Additional Funding.

      CEL-SCI's  estimates of the costs  associated  with future clinical trials
and  research  may be  substantially  lower  than  the  actual  costs  of  these
activities.  If  CEL-SCI's  cost  estimates  are  incorrect,  CEL-SCI  will need
additional funding for its research efforts.

Any failure to obtain or any delay in obtaining  required  regulatory  approvals
may  adversely  affect  the  ability  of  potential   licensees  or  CEL-SCI  to
successfully market any products they may develop.

      Therapeutic agents, drugs and diagnostic products are subject to approval,
prior to general  marketing,  by the FDA in the United  States and by comparable
agencies  in  most  foreign   countries.   The  process  of  obtaining  FDA  and
corresponding  foreign approvals is costly and time consuming,  particularly for
pharmaceutical  products  such as those which might  ultimately  be developed by
CEL-SCI, VTI or its licensees, and there can be no assurance that such approvals
will be granted.  Also, the extent of adverse government regulations which might
arise from future legislative or administrative action cannot be predicted.

CEL-SCI  has,  at the present  time,  only one source of  multikine  and if this
source  could not,  for any  reason,  supply  CEL-SCI  with  Multikine,  CEL-SCI
estimates that it would take  approximately six to ten months to obtain supplies
of Multikine under an alternative manufacturing arrangement.

       CEL-SCI  has  an  agreement  with  an  unrelated   corporation   for  the
production,  until August 2000, of Multikine for research and testing  purposes.
CEL-SCI does not know what cost it would incur to obtain an  alternative  source
of supply.

There can be no assurance  that  CEL-SCI will achieve or maintain a  competitive
position  or that  other  technological  developments  will not cause  CEL-SCI's
proprietary technologies to become uneconomical or obsolete.

      The biomedical  field in which CEL-SCI is involved is undergoing rapid and
significant  technological  change.  The  successful  development of therapeutic
agents  from   CEL-SCI's   compounds,   compositions   and   processes   through
CEL-SCI-financed research or as a result of possible licensing arrangements with

<PAGE>


pharmaceutical  or other  companies,  will  depend on its  ability  to be in the
technological forefront of this field.

      Many  pharmaceutical and biotechnology  companies are developing  products
for the prevention or treatment of cancer and AIDS. Many of these companies have
substantial financial, research and development, and marketing resources and are
capable of providing  significant  long-term  competition either by establishing
in-house  research  groups  or by  forming  collaborative  ventures  with  other
entities.  In addition,  both smaller companies and non-profit  institutions are
active in research  relating to cancer and AIDS and are  expected to become more
active in the future.

CEL-SCI's Patents Might Not Protect CEL-SCI's Technology from Competitors.

      Certain aspects of CEL-SCI's  technologies are covered by U.S. and foreign
patents. In addition, CEL-SCI has a number of patent applications pending. There
is no assurance that the applications still pending or which may be filed in the
future will  result in the  issuance of any  patents.  Furthermore,  there is no
assurance as to the breadth and degree of  protection  any issued  patents might
afford  CEL-SCI.  Disputes may arise between  CEL-SCI and others as to the scope
and validity of these or other  patents.  Any defense of the patents could prove
costly and time  consuming and there can be no assurance that CEL-SCI will be in
a position, or will deem it advisable, to carry on such a defense. Other private
and public concerns, including universities, may have filed applications for, or
may have been issued,  patents and are expected to obtain additional patents and
other  proprietary  rights to  technology  potentially  useful or  necessary  to
CEL-SCI.  The scope and  validity of such  patents,  if any, the extent to which
CEL-SCI may wish or need to acquire the rights to such patents, and the cost and
availability  of such  rights are  presently  unknown.  Also,  as far as CEL-SCI
relies upon unpatented proprietary technology, there is no assurance that others
may not  acquire  or  independently  develop  the  same or  similar  technology.
CEL-SCI's  first  MULTIKINE  patent will expire in the year 2000.  Since CEL-SCI
does not know if it will ever be able to sell  MULTIKINE on a commercial  basis,
CEL-SCI  cannot  predict what effect the  expiration of this patent will have on
CEL-SCI.  Notwithstanding  the above,  CEL-SCI  believes  that trade secrets and
later issued patents will protect the technology  associated with Multikine past
the year 2000.

CEL-SCI's  Product  Liability  Insurance May Not Be Adequate to Protect  CEL-SCI
from Possible Losses.

      Although  CEL-SCI has product  liability  insurance  for Multikine and its
HGP-30 vaccine,  the successful  prosecution of a product liability case against
CEL-SCI could have a materially  adverse  effect upon its business if the amount
of any judgment exceeds CEL-SCI's insurance coverage.

The Loss of Management and Scientific Personnel Could Adversely Affect CEL-SCI.
-------------------------------------------------------------------------------

      CEL-SCI is dependent for its success on the continued  availability of its
executive  officers.  The loss of the  services  of any of  CEL-SCI's  executive
officers  could have an adverse effect on CEL-SCI's  business.  CEL-SCI does not
carry key man life  insurance on any of its officers.  CEL-SCI's  future success
will also depend upon its  ability to attract  and retain  qualified  scientific

<PAGE>


personnel.  There  can be no  assurance  that  CEL-SCI  will be able to hire and
retain such necessary personnel.

Shares  Issuable  Upon the  Conversion  of  Options,  Warrants  and  Convertible
Securities May Depress the Price of CEL-SCI's Common stock.

      CEL-SCI  has issued  options to its  officers,  directors,  employees  and
consultants  which allow the holders to acquire  additional  shares of CEL-SCI's
common stock.  In some cases  CEL-SCI has agreed that,  at its expense,  it will
make appropriate filings with the Securities and Exchange Commission so that the
securities  issuable  upon the  exercise of the options  will be  available  for
public sale.  Such filings  could result in  substantial  expense to CEL-SCI and
could hinder future financings by CEL-SCI.

      Until the options  expire,  the holders will have an opportunity to profit
from any increase in the market price of CEL-SCI's common stock without assuming
the risks of ownership.  Holders of the options may exercise them at a time when
CEL-SCI  could  obtain  additional  capital on terms more  favorable  than those
provided by the  options.  The  exercise  of the options  will dilute the voting
interest of the owners of presently outstanding shares of CEL-SCI's common stock
and may adversely affect the ability of CEL-SCI to obtain additional  capital in
the future. The sale of the shares of common stock issuable upon the exercise of
the options could adversely affect the market price of CEL-SCI's stock.

         In December 1999 and January 2000, CEL-SCI sold 1,148,592 shares of its
common stock, plus Series A and Series B warrants,  to three private  investors.
The Series A warrants  permit the holders of the  warrants  to purchase  402,007
shares of  CEL-SCI's  common  stock at a price of  $2.925  per share at any time
prior to  December 8, 2002.  The Series B warrants  allow the  investors,  under
certain circumstances, to acquire additional shares of CEL-SCI's common stock at
a nominal price in the event:

o     The price of CEL-SCI's common stock falls below $2.4375 per share or

o        CEL-SCI raises in excess of $1,000,000 at a price which is below either
         the then prevailing  market price of CEL-SCI's  common stock or $2.4375
         per share.

         In March  2000,  CEL-SCI  sold an  additional  1,026,666  shares of its
common  stock,  plus Series C and Series D warrants,  to the same three  private
investors.  The Series C warrants permit the holders of the warrants to purchase
413,344  shares of  CEL-SCI's  common stock at a price of $8.50 per share at any
time prior to March 21, 2003. The Series D warrants  allow the investors,  under
certain circumstances, to acquire additional shares of CEL-SCI's common stock at
a nominal price in the event:

o     The price of CEL-SCI's common stock falls below $7.50 per share or

o        CEL-SCI raises in excess of $1,000,000 at a price which is below either
         the then prevailing market price of CEL-SCI's common stock or $7.50 per
         share.


<PAGE>

      Since the price of CEL-SCI's  common stock has been  volatile in the past,
investors could experience  substantial dilution upon the exercise of the Series
B or Series D warrants  if there is a decline in the market  price of  CEL-SCI's
common stock. See "Comparative Share Data".

      The shares of common stock sold in the December  1999,  January 2000,  and
March 2000 private  offerings,  as well as the shares of common  stock  issuable
upon the  exercise  of the Series A, B, C and D warrants  are being  offered for
public sale by means of this  prospectus.  The issuance of common stock upon the
exercise  of the Series A, B C and D warrants,  as well as future  sales of such
common stock,  or the perception  that such sales could occur,  could  adversely
affect the market price of CEL-SCI's common stock.

CEL-SCI may be  required  to make  payments to the holders of the Series B and D
warrants.

      In December 1999 and January 2000,  CEL-SCI sold  1,148,592  shares of its
common stock,  plus Series A and Series B warrants,  to three private  investors
for  $2,800,000.  The  Series  B  warrants  allow  the  holders,  under  certain
circumstances,  to acquire  additional  shares of  CEL-SCI's  common  stock at a
nominal  price in the event (i) the price of CEL-SCI's  common stock falls below
$2.44 per share prior to certain vesting dates, or (ii) CEL-SCI raises in excess
of $1,000,000 at a price which is below either the then prevailing  market price
of CEL-SCI's common stock or $2.44 per share.

      In March 2000,  CEL-SCI sold  1,026,666  shares of its common stock,  plus
Series C and  Series  D  warrants,  to the  same  three  private  investors  for
$7,700,000.  The  Series D  warrants  also  allow  the  holders,  under  certain
circumstances,  to acquire  additional  shares of  CEL-SCI's  common  stock at a
nominal  price in the event (i) the price of CEL-SCI's  common stock falls below
$7.50 per share prior to certain vesting dates, or (ii) CEL-SCI raises in excess
of $1,000,000 at a price which is below either the then prevailing  market price
of CEL-SCI's common stock or $7.50 per share.

      The actual number of shares issuable upon the exercise of the Series B and
Series D  warrants  (if any)  will  vary  depending  upon a number  of  factors,
including the price of CEL-SCI's common stock at certain dates.

      CEL-SCI's common stock trades on the American Stock Exchange. The rules of
the AMEX require a corporation,  the securities of which are listed on the AMEX,
to obtain  shareholder  approval if 20% or more of a corporation's  common stock
will be sold in a private  offering  and below the  greater of the book value or
market price of the corporation's common stock.

      For purposes of applying this particular rule to the Series B and Series D
warrants,  the AMEX will  consider  the  issuance  of any common  stock upon the
exercise of the Series B or Series D warrants to be a sale of  CEL-SCI's  common
stock at less than  market  price since the  exercise  price of the Series B and
Series D warrants is nominal.

      Consequently,  the AMEX rule would prohibit CEL-SCI from issuing more than
3,400,297 shares of common stock as a result of the exercise of the Series B and
Series D warrants  unless  shareholder  approval is obtained for the issuance of
the additional shares.

<PAGE>


      It is possible, depending upon the future market price of CEL-SCI's common
stock,  that more than 3,400,297 shares could be issued upon the exercise of the
Series B and Series D warrants.

      In order to avoid any violation of the AMEX rules relating to the issuance
of shares  below the market price of CEL-SCI's  common  stock,  the terms of the
Series B and Series D warrants provide that no more than 3,400,297 shares may be
issued  unless  CEL-SCI  obtains  shareholder  approval for the issuance of such
additional shares.

      If CEL-SCI  fails to obtain or elects not to obtain  shareholder  approval
for the issuance of the  additional  shares  CEL-SCI will be required to pay the
holders of the Series B and Series D warrants an amount equal to the then market
value of the shares which would  otherwise be issuable  upon the exercise of the
Series B or Series D warrants had shareholder approval been obtained.

The Market Price for CEL-SCI's Common Stock is Volatile.

      The market price of CEL-SCI's  common stock,  as well as the securities of
other  biopharmaceutical  and  biotechnology  companies,  have historically been
highly volatile,  and the market has from time to time  experienced  significant
price and volume fluctuations that are unrelated to the operating performance of
particular  companies.  Factors  such as  fluctuations  in  CEL-SCI's  operating
results,  announcements of technological innovations or new therapeutic products
by CEL-SCI or its competitors,  governmental regulation,  developments in patent
or other  proprietary  rights,  public  concern  as to the  safety  of  products
developed by CEL-SCI or other  biotechnology and pharmaceutical  companies,  and
general market  conditions may have a significant  effect on the market price of
CEL-SCI's common stock.

                             COMPARATIVE SHARE DATA

      As of May 31, 2000, the shareholders of CEL-SCI owned 20,439,209 shares of
common stock. The following table illustrates the comparative stock ownership of
the present  shareholders  of CEL-SCI,  as  compared  to the  investors  in this
offering, assuming all warrants held by the selling shareholders are exercised.

                                                  Number of            Note
                                                   Shares            Reference

   Shares outstanding as of May 31, 2000         20,439,209

   Shares offered by selling shareholders:

   Shares purchased from CEL-SCI                  1,601,058            A and B

   Shares issuable upon exercise of                 402,007            A
   Series A warrants

   Shares issuable upon exercise of
   Series B warrants                                     --            A

<PAGE>


   Shares issuable upon exercise of                 413,344            B
   Series C warrants

   Shares issuable upon exercise of
   Series D warrants                              1,540,000            B

   Shares issuable upon exercise of                  25,000            C
   sales agent warrants

   Shares which will be outstanding, assuming the
   exercise of all warrants listed above         22,794,560

   Percentage of CEL-SCI's  common stock  represented  by shares offered by this
   prospectus, assuming the exercise of all warrants listed above 17.6%

      The number of shares  outstanding as of May 31, 2000 excludes shares which
may be issued upon the exercise and/or conversion of options, warrants and other
convertible securities previously issued by CEL-SCI. See table below.

Other Shares Which May Be Issued:
--------------------------------

      The  following  table lists  additional  shares of CEL-SCI's  common stock
which may be  issued  as the  result of the  exercise  of  outstanding  options,
warrants or the conversion of other securities issued by CEL-SCI:

                                                  Number of            Note
                                                   Shares           Reference

   Shares issuable upon exercise of               1,100,000            D
   warrants sold to investors in
   December 1997 private offering

   Shares issuable upon exercise of
   options granted to investor relations
   consultants                                      115,000            E

   Shares  issuable upon  exercise of
   options and warrants  granted to
   CEL-SCI's  officers, directors,
   employees, consultants, and third
   parties                                        3,270,048            F

A. In December  1999 and January  2000,  CEL-SCI  sold  1,148,592  shares of its
common  stock,  plus  Series A and  Series  B  warrants,  to a group of  private
investors for  $2,800,000.  As of May 31, 2000 these private  investors had sold
529,200  shares  which they  purchased  in the  private  offering.  The Series A
warrants allow the holders to purchase up to 402,007 shares of CEL-SCI's  common

<PAGE>

stock at a price of $2.925 per share at any time prior to December 8, 2002.  The
Series B warrants  allow the holders,  under certain  circumstances,  to acquire
additional shares of CEL-SCI's common stock at a nominal price in the event:

o    the price of CEL-SCI's  common stock falls below $2.4375 per share prior to
     certain fixed vesting dates, or
o        CEL-SCI raises in excess of $1,000,000 at a price which is below either
         the then prevailing  market price of CEL-SCI's  common stock or $2.4375
         per share.

      The fixed vesting dates for the purposes of the Series B warrants are:

                                December 8, 2000
                                  June 8, 2001
                                December 8, 2001
                                  June 8, 2002
                                December 8, 2002

      Other vesting dates will occur when an extraordinary event occurs, such as
a change in the control of CEL-SCI, the bankruptcy or liquidation of CEL-SCI, or
the  failure  of  CEL-SCI's  common  stock to be  listed on the  American  Stock
Exchange, the NASDAQ Stock Market or the NASDAQ SmallCap market.

      Upon the  occurrence of a vesting  date,  the  additional  shares (if any)
which  CEL-SCI will be required to issue to the holders of the Series B warrants
will be determined in accordance with the following formula:

            [(C x PA) / A]  -  C

C    = The number of shares purchased by the Series B warrant holder and not yet
     sold

            PA          = The Adjustment  Price from the  immediately  preceding
                        vesting date or, with respect to the first vesting date,
                        $2.4375.

            A           =  Adjustment  price,  which is equal to the  lesser  of
                        $2.4375,  or the  average of the 10 lowest  closing  bid
                        prices of  CEL-SCI's  common stock during the 30 trading
                        days immediately preceding the vesting date.

      In addition to the  foregoing,  if CEL-SCI  raises in excess of $1,000,000
through the sale of common stock, or securities  convertible  into common stock,
at a price which is below either the then  prevailing  market price of CEL-SCI's
common  stock or $2.4375  per share,  then the  holders of the Series B warrants
will be entitled  to receive  additional  shares of  CEL-SCI's  common  stock in
accordance with the following formula:

            [(C x $2.4375) / D]  -  C


<PAGE>


            C           = The number of shares purchased by the Series B warrant
                        holder and not yet sold on the date of the financing.

            D           = An amount  equal to the  lesser of the  average of the
                        closing bid prices of CEL-SCI's  common stock for the 10
                        trading  days  immediately  preceding  the  date  of the
                        financing,  or the price per share of the common  stock,
                        or common stock equivalent (as the case may be), sold in
                        the financing.

      The actual  number of shares  issuable  upon the  exercise of the Series B
warrants (if any) will vary  depending  upon a number of factors,  including the
price of CEL-SCI's  common stock at certain  dates.  Accordingly,  the number of
shares (if any) which may be issued  upon the  exercise of the Series B warrants
cannot be  determined  at this time.  However,  based  upon the market  price of
CEL-SCI's  common stock on May 31, 2000,  CEL-SCI would not be required to issue
any material  shares of its common stock if the Series B warrants were exercised
as of that date.

B. In March 2000, CEL-SCI sold 1,026,666 shares of its common stock, plus Series
C and Series D warrants, to the same private investors referred to in Note A for
$7,700,000.  The Series C warrants  allow the  holders to purchase up to 413,344
shares of CEL-SCI's common stock at a price of $8.50 per share at any time prior
to March 21,  2003.  The  Series D warrants  allow the  holders,  under  certain
circumstances,  to acquire  additional  shares of  CEL-SCI's  common  stock at a
nominal price in the event:

o    the price of  CEL-SCI's  common  stock falls below $7.50 per share prior to
     certain fixed vesting dates, or
o          CEL-SCI  raises  in excess of  $1,000,000  at a price  which is below
           either the then prevailing  market price of CEL-SCI's common stock or
           $7.50 per share.

      The fixed vesting dates for the purposes of the Series D warrants are:

                                 March 16, 2001
                               September 16, 2001
                                 March 16, 2002
                               September 16, 2002
                                 March 16, 2003

      Other vesting dates will occur when an extraordinary event occurs, such as
a change in the control of CEL-SCI, the bankruptcy or liquidation of CEL-SCI, or
the  failure  of  CEL-SCI's  common  stock to be  listed on the  American  Stock
Exchange, the NASDAQ Stock Market or the NASDAQ SmallCap market.

      Upon the  occurrence of a vesting  date,  the  additional  shares (if any)
which  CEL-SCI will be required to issue to the holders of the Series D warrants
will be determined in accordance with the following formula:

            [(C x PA) / A]  -  C

<PAGE>


            C     =     The number of shares purchased by the Series D warrant
                        holder and not yet sold

            PA          = The Adjustment  Price from the  immediately  preceding
                        vesting date or, with respect to the first vesting date,
                        $7.50.

            A           =  Adjustment  price,  which is equal to the  lesser  of
                        $7.50,  or the  average  of the 10  lowest  closing  bid
                        prices of  CEL-SCI's  common stock during the 30 trading
                        days immediately preceding the vesting date.

      In addition to the  foregoing,  if CEL-SCI  raises in excess of $1,000,000
through the sale of common stock, or securities  convertible  into common stock,
at a price which is below either the then  prevailing  market price of CEL-SCI's
common stock or $7.50 per share,  then the holders of the Series D warrants will
be entitled to receive additional shares of CEL-SCI's common stock in accordance
with the following formula:

            [(C x $7.50) / D]  -  C

            C           = The number of shares purchased by the Series D warrant
                        holder and not yet sold on the date of the financing.

            D           = An amount  equal to the  lesser of the  average of the
                        closing bid prices of CEL-SCI's  common stock for the 10
                        trading  days  immediately  preceding  the  date  of the
                        financing,  or the price per share of the common  stock,
                        or common stock equivalent (as the case may be), sold in
                        the financing.

      The actual  number of shares  issuable  upon the  exercise of the Series D
warrants (if any) will vary  depending  upon a number of factors,  including the
price of CEL-SCI's  common stock at certain  dates.  Accordingly,  the number of
shares (if any) which may be issued  upon the  exercise of the Series D warrants
cannot be  determined  at this time.  Based upon the market  price of  CEL-SCI's
common  stock on May 31,  2000,  CEL-SCI  would be required  to issue  1,540,000
shares of its common  stock if the Series D warrants  were  exercised as of that
date.

C.  In  connection  with  CEL-SCI's  December  1999  sale of  common  stock  and
    warrants,  Reedland  Capital  Partners,  a division of Financial West Group,
    acted as the sales agent for such  offering  and  received a  commission  of
    $125,000  plus  Series A warrants  to purchase  25,000  shares of  CEL-SCI's
    common stock.  The sales agent warrants are exercisable at a price of $2.925
    per share at any time prior to December 8, 2002.  The shares  issuable  upon
    the exercise of the sales agent  warrants are being  offered for sale to the
    public by means of this prospectus. See "Selling Shareholders".

D.  In  December  1997,  CEL-SCI  sold  10,000  shares of its Series D Preferred
    Stock,  and  1,100,000   warrants,   to  ten  institutional   investors  for
    $10,000,000.  All Series D Preferred shares were subsequently converted into
    5,201,400  shares of CEL-SCI's  common  stock.  Warrants for the purchase of
    550,000  shares of common stock are  exercisable  at a price of $8.62 at any
    time prior to December 22, 2001. Warrants for the purchase of 550,000 shares
    of common  stock are  exercisable  at a price of $9.31 at any time  prior to

<PAGE>

    December  22,  2001.  As of December  31, 1999 none of the warrants had been
    exercised.  The shares  issuable  upon the  exercise of  warrants  are being
    offered for sale to the public by means of a separate registration statement
    which has been filed with the Securities and Exchange Commission.

E.  CEL-SCI has granted  options  for the  purchase of 115,000  shares of common
    stock  to  certain  investor  relations  consultants  in  consideration  for
    services provided to CEL-SCI.  The options are exercisable at prices ranging
    between $2.50 and $5.00 per share and expire  between June 2000 and February
    2004.  The 115,000  shares  issuable  upon the exercise of these options are
    being  offered  for sale to the public by means of a  separate  registration
    statement which has been filed with the Securities and Exchange Commission.

F.  The  options  are  exercisable  at prices  ranging  from $1.87 to $11.00 per
    share.  CEL-SCI may also grant options to purchase  additional  shares under
    its Incentive Stock Option and Non-Qualified Stock Option Plans.


                              SELLING SHAREHOLDERS

      In December 1999 and January 2000,  CEL-SCI sold  1,148,592  shares of its
common stock, plus Series A and Series B warrants,  to three private  investors.
The Series A warrants  permit the holders of the  warrants  to purchase  402,007
shares of  CEL-SCI's  common  stock at a price of  $2.925  per share at any time
prior to  December 8, 2002.  The Series B warrants  allow the  investors,  under
certain circumstances, to acquire additional shares of CEL-SCI's common stock at
a nominal price in the event:

o     The price of CEL-SCI's common stock falls below $2.4375 per share or

o        CEL-SCI raises in excess of $1,000,000 at a price which is below either
         the then prevailing  market price of CEL-SCI's  common stock or $2.4375
         per share.

      In March 2000  CEL-SCI sold  1,026,666  shares of its common  stock,  plus
Series C and  Series  D  warrants,  to three  private  investors.  The  Series C
warrants  permit the  holders of the  warrants  to  purchase  413,344  shares of
CEL-SCI's  common stock at a price of $8.50 per share at any time prior to March
21,  2003.   The  Series  D  warrants   allow  the   investors,   under  certain
circumstances,  to acquire  additional  shares of  CEL-SCI's  common  stock at a
nominal price in the event

o     the price of CEL-SCI's common stock falls below $7.50 per share, or
o    CEL-SCI raises in excess of $1,000,000 at a price which is below either the
     then prevailing market price of CEL-SCI's common stock or $7.50 per share.

      The actual number of shares issuable upon the exercise of the Series B and
Series D  warrants  (if any)  will  vary  depending  upon a number  of  factors,
including the price of CEL-SCI's common stock at certain dates. Accordingly, the
number of  shares  which may be issued  upon the  exercise  of the  Series B and
Series D warrants  cannot be determined  at this time.  See  "Comparative  Share
Data".  The shares sold to the three  investors,  as well as the shares issuable

<PAGE>

upon the exercise of the Series A, B, C and D warrants, are being offered to the
public by means of this prospectus.

      In connection with the December 1999 financing, Reedland Capital Partners,
and  Institutional  Division of Financial  West Group,  received a commission of
$125,000 plus Series A warrants to purchase  25,000  shares of CEL-SCI's  common
stock at $2.925 per share for its role as sales  agent.  The  25,000  shares are
also being offered to the public by means of this prospectus.

      The three  private  investors  and the sales agent are referred to in this
prospectus as the "selling shareholders".  CEL-SCI will not receive any proceeds
from the sale of the shares by the selling shareholders.

      The names of the selling shareholders are:

                                                Shares
                          Shares      Shares    Which
                          Which       Which     May Be
                         May be      May be     Acquired
                        Acquired    Acquired      Upon                  Share
                          Upon        Upon     Exercise of   Shares to  Owner
                       Exercise of  Exercise of Series B and  be Sold   ship
                Shares   Series A    Series C   Series D      in this   After
  Name          Owned    Warrants    Warrants    Warrants    Offering  Offering
--------------  -----    --------    --------    --------    --------- --------
                 (1)                           (2)
Advantage
  Fund II Ltd. 924,546   287,179    214,724      800,000   2,226,449        --
Koch Investment
  Group, Ltd.  460,228    71,795    161,043      600,000   1,293,066        --
Mooring
 Capital Fund
 LLC           216,284    43,033     37,577      140,000     436,894        --
Reedland Capital
  Partners          --    25,000         --           --      25,000        --
          ----------------------------------------------------------------------
             1,601,058   427,007    413,344    1,540,000   3,981,409
             =========   =======    =======    =========   =========

(1)  Excludes  shares  issuable  upon the  exercise  of the  Series A, B, C or D
warrants.  See "Comparative Share Data" for information  concerning the terms of
these warrants.  Share  ownership  represents  shares  purchased in the December
1999/January 2000 and the March 2000 private offerings.

                                    Shares Purchased
                          December 1999/               Less Shares
                          January 2000    March 2000   Sold as of   Total Shares
Selling Shareholder                        Offering     Offering        Owned
                                         June 7, 2000

Advantage Fund II Ltd.      820,513        533,333      (429,300)      924,546
Koch Investment Group, Ltd. 205,128        400,000      (144,900)      460,228
Mooring Capital Fund LLC    122,951         93,333            --       216,284
                         ----------       ---------                  ----------


<PAGE>

                          1,148,592      1,026,666                   1,601,058
                          =========      =========                   =========

(2)Based upon the price of CEL-SCI's  common stock as of May 31, 2000, no shares
     would be  issuable  pursuant  to the  terms of the  Series B  warrants  and
     approximately  1,540,000 shares would be issuable  pursuant to the terms of
     the Series D warrants.

      For purposes of the foregoing  table, it is assumed that all shares owned,
or which may be acquired,  by the selling shareholders are sold to the public by
means of this prospectus.

     Genesee   International  Inc.,  of  which  Mr.  Donald  R.  Morken  is  the
controlling  stockholder,  has voting and  investment  power over the securities
beneficially  owned by Advantage  Fund II Ltd. Koch  Industries,  Inc., of which
Messrs.  Charles Koch and David Koch are controlling  stockholders,  have voting
and investment power over the securities  beneficially  owned by Koch Investment
Group Ltd.  Mooring  Capital Fund LLC is  controlled by John M.  Jacquemin.  Mr.
Jacquemin is a director of CEL-SCI Corporation.

      Each Series A and Series B warrant  holder is prohibited  from  exercising
the  warrants  to the extent that such  exercise  would  result in such  holder,
together with any affiliate of the warrant holder, beneficially owning in excess
of 4.999% of the  outstanding  shares of CEL-SCI's  common stock  following such
exercise.  This  restriction  may be waived  by each  holder on not less than 61
days' notice to CEL-SCI.  However,  the 4.999% limitation would not prevent each
warrant  holder  from  acquiring  and  selling in excess of 4.999% of  CEL-SCI's
common stock  through a series of  acquisitions  and sales under the warrants so
long as the warrant holder never beneficially owns more than 4.999% of CEL-SCI's
common stock at any one time.

      Each Series C and Series D warrant  holder is prohibited  from  exercising
the  warrants  to the extent that such  exercise  would  result in such  holder,
together with any affiliate of the warrant holder, beneficially owning in excess
of 9.999% of the  outstanding  shares of CEL-SCI's  common stock  following such
exercise.  This  restriction  may be waived  by each  holder on not less than 61
days' notice to CEL-SCI.  However,  the 9.999% limitation would not prevent each
warrant  holder  from  acquiring  and  selling in excess of 9.999% of  CEL-SCI's
common stock  through a series of  acquisitions  and sales under the warrants so
long as the warrant holder never beneficially owns more than 9.999% of CEL-SCI's
common stock at any one time.

Plan of Distribution

      The  selling  shareholders  and  any  of  their  pledgees,  assignees  and
successors-in-interest  may, from time to time,  sell any or all of their shares
of common stock on any stock exchange,  market or trading  facility on which the
shares  are traded or in private  transactions.  These  sales may be at fixed or
negotiated  prices.  The  selling  shareholders  may  use any one or more of the
following methods when selling shares:


<PAGE>



o    ordinary brokerage transactions and transactions in which the broker-dealer
     solicits purchasers;
o     block trades in which the broker-dealer will attempt to sell the shares as
      agent but may  position  and resell a portion of the block as principal to
      facilitate the transaction;
o    purchases by a broker-dealer  as principal and resale by the  broker-dealer
     for its account;
o    an exchange  distribution  in accordance  with the rules of the  applicable
     exchange; o privately negotiated transactions;
o     short sales;
o    broker-dealers may agree with the Selling  Stockholders to sell a specified
     number of such shares at a stipulated price per share;
o    a combination of any such methods of sale; and
o    any other method permitted pursuant to applicable law.

      The selling  shareholders  may also sell  shares  under Rule 144 under the
Securities Act, if available, rather than under this prospectus.

      The selling  shareholders  may also engage in short sales against the box,
puts and calls and other transactions in securities of CEL-SCI or derivatives of
CEL-SCI  securities  and may sell or  deliver  shares in  connection  with these
trades. The selling  shareholders may pledge their shares to their brokers under
the margin provisions of customer agreements.  If a selling shareholder defaults
on a margin loan, the broker may, from time to time,  offer and sell the pledged
shares.

      Broker-dealers  engaged by the selling  shareholders may arrange for other
brokers-dealers to participate in sales.  Broker-dealers may receive commissions
or discounts from the selling  shareholders  (or, if any  broker-dealer  acts as
agent  for the  purchaser  of  shares,  from the  purchaser)  in  amounts  to be
negotiated.  The  selling  shareholders  do not  expect  these  commissions  and
discounts to exceed what is customary in the types of transactions involved.

      The  selling  shareholders  and any  broker-dealers  or  agents  that  are
involved  in selling  the shares may be deemed to be  "underwriters"  within the
meaning of the Securities Act in connection with such sales. In such event,  any
commissions  received  by such  broker-dealers  or agents  and any profit on the
resale  of the  shares  purchased  by  them  may be  deemed  to be  underwriting
commissions or discounts under the Securities Act.

      CEL-SCI  is  required  to  pay  all  fees  and  expenses  incident  to the
registration of the shares,  including fees and  disbursements of counsel to the
selling  shareholders.  CEL-SCI has agreed to indemnify the selling shareholders
against certain losses, claims,  damages and liabilities,  including liabilities
under the Securities Act.

      CEL-SCI  has  advised  the  selling  shareholders  that in the  event of a
"distribution"  of the shares  owned by the selling  shareholder,  such  selling
shareholders, any "affiliated purchasers", and any broker/dealer or other person
who  participates  in such  distribution  may be  subject  to Rule 102 under the
Securities  Exchange Act of 1934 ("1934 Act") until their  participation in that
distribution  is  completed.  A  "distribution"  is  defined  in Rule  102 as an
offering of securities "that is distinguished from ordinary trading transactions
by the magnitude of the offering and the presence of special selling efforts and
selling  methods".  CEL-SCI has also advised the selling  shareholders that Rule
102 under the 1934 Act prohibits any "stabilizing bid" or "stabilizing purchase"

<PAGE>

for the purpose of pegging,  fixing or stabilizing the price of the common stock
in connection with this offering.  Rule 101 makes it unlawful for any person who
is  participating  in a  distribution  to bid for or purchase  stock of the same
class as is the subject of the distribution.

      CEL-SCI  has  agreed  to  indemnify  the  selling   shareholders  and  any
securities  broker/dealers who may be deemed to be underwriters  against certain
liabilities,  including  liabilities under the Securities Act as underwriters or
otherwise.

                            DESCRIPTION OF SECURITIES

Common Stock

      CEL-SCI is authorized to issue  100,000,000  shares of common stock,  (the
"common stock").  Holders of common stock are each entitled to cast one vote for
each share held of record on all matters  presented to shareholders.  Cumulative
voting is not  allowed;  hence,  the  holders of a majority  of the  outstanding
common stock can elect all directors.

      Holders of common stock are  entitled to receive such  dividends as may be
declared by the Board of Directors out of funds legally available  therefor and,
in the event of liquidation,  to share pro rata in any distribution of CEL-SCI's
assets after  payment of  liabilities.  The board is not  obligated to declare a
dividend.  It is not anticipated  that dividends will be paid in the foreseeable
future.

      Holders of common  stock do not have  preemptive  rights to  subscribe  to
additional  shares if issued by CEL-SCI.  There are no  conversion,  redemption,
sinking  fund or similar  provisions  regarding  the  common  stock . All of the
outstanding shares of Common stock are fully paid and non-assessable.

Preferred Stock

      CEL-SCI is  authorized to issue up to 200,000  shares of preferred  stock.
CEL-SCI's Articles of Incorporation  provide that the Board of Directors has the
authority to divide the preferred  stock into series and, within the limitations
provided  by  Colorado   statute,   to  fix  by  resolution  the  voting  power,
designations,  preferences, and relative participation,  special rights, and the
qualifications,  limitations  or  restrictions  of the  shares of any  series so
established.  As the Board of Directors has authority to establish the terms of,
and to issue, the preferred stock without  shareholder  approval,  the preferred
stock could be issued to defend against any attempted takeover of CEL-SCI.

      See "Comparative Share Data" for information concerning CEL-SCI's Series D
preferred stock.

Transfer Agent

     American Securities Transfer,  Inc., of Denver,  Colorado,  is the transfer
agent for CEL-SCI's common stock.



<PAGE>


                                     EXPERTS

      The  consolidated  financial  statements  of  CEL-SCI  Corporation  as  of
September 30, 1999 and 1998, and for each of the three years in the period ended
September 30, 1999  incorporated  by reference in this prospectus from CEL-SCI's
Annual  Report on Form 10-K for the year ended  September  30,  1999,  have been
audited  by  Deloitte & Touche  LLP,  independent  auditors,  as stated in their
report, which is incorporated herein by reference, and have been so incorporated
in reliance  upon the report of such firm given upon their  authority as experts
in accounting and auditing.

                                 INDEMNIFICATION

      CEL-SCI's  bylaws  authorize  indemnification  of  a  director,   officer,
employee or agent of CEL-SCI against expenses incurred by him in connection with
any action,  suit,  or  proceeding to which he is named a party by reason of his
having acted or served in such capacity, except for liabilities arising from his
own  misconduct or negligence in  performance  of his duty. In addition,  even a
director,  officer,  employee,  or agent of  CEL-SCI  who was found  liable  for
misconduct  or  negligence  in the  performance  of his  duty  may  obtain  such
indemnification  if, in view of all the  circumstances  in the case,  a court of
competent jurisdiction  determines such person is fairly and reasonably entitled
to indemnification. Insofar as indemnification for liabilities arising under the
Securities  Act of 1933 may be  permitted  to  directors,  officers,  or persons
controlling  CEL-SCI  pursuant  to the  foregoing  provisions,  CEL-SCI has been
informed that in the opinion of the  Securities  and Exchange  Commission,  such
indemnification  is  against  public  policy  as  expressed  in the  Act  and is
therefore unenforceable.

                             ADDITIONAL INFORMATION

      CEL-SCI is subject to the  requirements of the Securities  Exchange Act of
l934 and is required to file reports,  proxy  statements  and other  information
with the Securities and Exchange Commission.  Copies of any such reports,  proxy
statements and other  information filed by CEL-SCI can be read and copied at the
Commission's Public Reference Room at 450 Fifth Street, N.W., Washington,  D.C.,
20549.  The  public  may  obtain  information  on the  operation  of the  Public
Reference  Room by calling the  Commission  at  1-800-SEC-0330.  The  Commission
maintains  an  Internet  site  that  contains  reports,  proxy  and  information
statements, and other information regarding CEL-SCI. The address of that site is
http://www.sec.gov.

      CEL-SCI will  provide,  without  charge,  to each person to whom a copy of
this prospectus is delivered,  including any beneficial  owner, upon the written
or  oral  request  of  such  person,  a copy  of  any  or  all of the  documents
incorporated by reference below (other than exhibits to these documents,  unless
the exhibits are specifically  incorporated by reference into this  prospectus).
Requests should be directed to:

                               CEL-SCI Corporation
                             8229 Boone Blvd., #802
                             Vienna, Virginia 22182
                                 (703) 506-9460

<PAGE>


         The  following   documents   filed  with  the   Commission  by  CEL-SCI
(Commission   File  No.  0-11503)  are   incorporated  by  reference  into  this
prospectus:

(1) CEL-SCI's Annual Report on Form 10-K for the fiscal year ended September 30,
1999.

(2) CEL-SCI's  Quarterly  Report  (unaudited) on Form 10-Q for the quarter ended
December 31, 1999.

(3)  CEL-SCI's  Proxy  Statement  relating to the March 17,  2000  shareholders'
     meeting.

      All documents filed with the Securities and Exchange Commission by CEL-SCI
pursuant to Sections 13(a), 13(c), 14 or 15(d) of the Exchange Act subsequent to
the date of this  prospectus and prior to the termination of this offering shall
be deemed to be  incorporated by reference into this prospectus and to be a part
of this prospectus from the date of the filing of such documents.  Any statement
contained in a document  incorporated  or deemed to be incorporated by reference
shall be deemed to be modified or superseded for the purposes of this prospectus
to  the  extent  that  a  statement  contained  in  this  prospectus  or in  any
subsequently  filed  document which also is or is deemed to be  incorporated  by
reference  herein  modifies or  supersedes  such  statement.  Such  statement so
modified or superseded shall not be deemed, except as so modified or superseded,
to constitute a part of this prospectus.

      CEL-SCI  has  filed  with  the  Securities   and  Exchange   Commission  a
Registration  Statement  under the  Securities  Act of l933,  as  amended,  with
respect to the securities  offered by this prospectus.  This prospectus does not
contain all of the  information  set forth in the  Registration  Statement.  For
further  information with respect to CEL-SCI and such  securities,  reference is
made  to  the  Registration  Statement  and  to  the  exhibits  filed  with  the
Registration  Statement.  Statements  contained  in  this  prospectus  as to the
contents  of any  contract  or  other  documents  are  summaries  which  are not
necessarily complete, and in each instance reference is made to the copy of such
contract or other  document filed as an exhibit to the  Registration  Statement,
each such  statement  being  qualified  in all respects by such  reference.  The
Registration  Statement  and  related  exhibits  may  also  be  examined  at the
Commission's internet site.



<PAGE>


      No  dealer  salesman  or  other  person  has been  authorized  to give any
information or to make any  representations,  other than those contained in this
prospectus.  Any information or representation  not contained in this prospectus
must not be relied upon as having been  authorized by CEL-SCI.  This  prospectus
does not constitute an offer to sell, or a solicitation  of an offer to buy, the
securities  offered hereby in any state or other  jurisdiction  to any person to
whom it is unlawful to make such offer or solicitation.  Neither the delivery of
this  prospectus nor any sale made  hereunder  shall,  under any  circumstances,
create an  implication  that there has been no change in the  affairs of CEL-SCI
since the date of this prospectus.




                                TABLE OF CONTENTS

                                                                       Page
Prospectus Summary..................................                    5
Risk Factors........................................                    9
Comparative Share Data..............................                    12
Selling shareholders................................                    15
Description of Securities...........................                    19
Experts.............................................                    20
Indemnification.....................................                    20
Additional Information..............................                    21

                        ------------------------------
                                  Common stock

                               CEL-SCI CORPORATION

                                   PROSPECTUS







<PAGE>


                                     PART II
                     Information Not Required in Prospectus


Item 14.  Other Expenses of Issuance and Distribution

             SEC Filing Fee                                    $  3,575
             Blue Sky Fees and Expenses                           2,000
             Printing and Engraving Expenses                      2,000
             Legal Fees and Expenses                             20,000
             Accounting Fees and Expenses                         3,000
             Miscellaneous Expenses                               4,425
                                                              ---------

             TOTAL                                              $35,000
                                                                =======

             All expenses other than the S.E.C. filing fees are estimated.

Item 25.  Indemnification of Officers and Directors.
          -----------------------------------------

      It is provided by Section  7-109-102 of the Colorado  Revised Statutes and
CEL-SCI's  Bylaws  that  CEL-SCI  may  indemnify  any and  all of its  officers,
directors,  employees  or agents or former  officers,  directors,  employees  or
agents,   against  expenses  actually  and  necessarily  incurred  by  them,  in
connection  with  the  defense  of any  legal  proceeding  or  threatened  legal
proceeding,  except as to matters in which such persons  shall be  determined to
not have acted in good faith and in the best interest of CEL-SCI.

Item 16.  Exhibits

3(a)                        Articles of Incorporation Incorporated  by reference
                            to Exhibit 3(a) of CEL-SCI's  combined  Registration
                            Statement on Form S-1 and  Post-Effective  Amendment
                            ("Registration   Statement"),    Registration   Nos.
                            2-85547-D and 33-7531.

 (b)                        Amended Articles    Incorporated   by  reference  to
                            Exhibit 3(a) of CEL-SCI's  Registration Statement on
                            Form S-1, Registration Nos. 2-85547-D and 33-7531.

 (c)  Amended Articles
     (Name change only)     Filed   as   Exhibit   3(c)   to   CEL-SCI's
                            Registration  Statement  on  Form  S-1  Registration
                            Statement (No. 33-34878).

 (d)     Bylaws             Incorporated   by   reference  to  Exhibit  3(b)  of
                            CEL-SCI's   Registration   Statement  on  Form  S-1,
                            Registration Nos. 2-85547-D and 33-7531.





<PAGE>


(a)   Specimen copy of        Incorporated  by  reference  to Exhibit 4(a) Stock
      Certificate             of CEL-SCI's Registration Statement on
                              Form S-1 Registration Nos. 2-85547-D and 33-7531.

5.    Opinion of Counsel

10(e) Employment Agreement with           Filed with Amendment Number 1 to CEL-
      Geert Kersten
                                          SCI's Registration Statement on Form
                                          S-1 (Commission File Number 33-43281).

10(i) Securities Purchase Agreement
     (with  schedule)                Incorporated by reference to Exhibit 10(i)
                                     to Cel-Sci   Registration   Statement   on
                                   Form  S-3 (Commission File Number 333-94675).

10(j)                                     Form of  Callable  (Series  A) Warrant
                                          Incorporated  by  reference to Exhibit
                                          10(j)    to    Cel-Sci    Registration
                                          Statement on Form S-3 (Commission File
                                          Number 333-94675).

10(k) Form of Adjustable (Series B)
      Warrant                             Incorporated  by  reference to Exhibit
                                          10(k)    to    Cel-Sci    Registration
                                          Statement on Form S-3 (Commission File
                                          Number 333-94675).

10(l) Registration Rights Agreement      Incorporated  by reference  to Exhibit
                                         10(l) to Cel-Sci Registration Statement
                                         on  Form  S-3 (Commission File Number
                                         333-94675).

10(m) Securities Purchase Agreement,
      together with Schedule required
      by Instruction 2 to Item 601 Regulation S-K
                                                        *
                                          -----------------------------

10(n) Form of Callable (Series C) Warrant               *
                                          ----------------------------

10(o) Form of Adjustable (Series D) Warrant
                                                        *
                                          ----------------------------

10(p) Registration Rights Agreement
                                                        *
                                          ----------------------------

23(a) Consent of Hart & Trinen            ----------------------------


    (b)  Consent of Deloitte & Touche, LLP              *
                                          -------------------------------

*   Previously Filed



<PAGE>


Item 17. Undertakings.
         ------------

      The undersigned Registrant hereby undertakes:

      (1) To file,  during any period in which offers or sales are being made, a
post-effective amendment to this Registration Statement.

(i)  To include any  prospectus  required by Section  l0(a)(3) of the Securities
     Act of l933;

            (ii) To reflect in the  prospectus any facts or events arising after
the  effective  date  of  the   Registration   Statement  (or  the  most  recent
post-effective  amendment  thereof)  which,  individually  or in the  aggregate,
represent a fundamental  change in the information set forth in the Registration
Statement;

            (iii) To include any material  information  with respect to the plan
of distribution not previously  disclosed in the  Registration  Statement or any
material change to such  information in the  Registration  Statement,  including
(but not limited to) any addition or deletion of a managing underwriter.

         (2) That,  for the  purpose  of  determining  any  liability  under the
Securities Act of l933, each such post-effective amendment shall be deemed to be
a new registration statement relating to the securities offered therein, and the
offering of such  securities at that time shall be deemed to be the initial bona
fide offering thereof.

         (3) To remove from registration by means of a post-effective  amendment
any of the securities being registered which remain unsold at the termination of
the offering.

         Insofar as indemnification for liabilities arising under the Securities
Act of l933 may be permitted to directors,  officers and controlling  persons of
the  Registrant,  the  Registrant  has been  advised  that in the opinion of the
Securities and Exchange Commission such indemnification is against public policy
as expressed in the Act and is,  therefore,  unenforceable.  In the event that a
claim for  indemnification  against such liabilities  (other than the payment by
the  Registrant  of  expenses  incurred  or  paid  by  a  director,  officer  or
controlling  person of the Registrant in the  successful  defense of any action,
suit or proceeding) is asserted by such director,  officer or controlling person
in connection with the securities being registered,  the Registrant will, unless
in the  opinion  of its  counsel  the matter  has been  settled  by  controlling
precedent, submit to a court of appropriate jurisdiction the question of whether
such  indemnification by it is against public policy as expressed in the Act and
will be governed by the final adjudication of such issue.



<PAGE>


                                POWER OF ATTORNEY

         The  registrant  and each person whose  signature  appears below hereby
authorizes the agent for service named in this Registration Statement, with full
power to act alone,  to file one or more  amendments  (including  post-effective
amendments)  to this  Registration  Statement,  which  amendments  may make such
changes  in  this  Registration  Statement  as  such  agent  for  service  deems
appropriate,  and the Registrant and each such person hereby appoints such agent
for service as attorney-in-fact, with full power to act alone, to execute in the
name and in behalf of the  Registrant and any such person,  individually  and in
each capacity stated below, any such amendments to this Registration Statement.

                                   SIGNATURES

         Pursuant  to the  requirements  of the  Securities  Act  of  l933,  the
Registrant certifies that it has reasonable grounds to believe that it meets all
the  requirements  for filing on Form S-3 and has duly caused this  Registration
Statement  to be  signed  on its  behalf  by  the  undersigned,  thereunto  duly
authorized,  in the City of Vienna,  State of Virginia,  on the 8th day of June,
2000.

                                       CEL-SCI CORPORATION


                                       By:   /s/  Maximilian de Clara
                                             ----------------------------------
                                              Maximilian de Clara, President

      Pursuant  to  the  requirements  of  the  Securities  Act  of  l933,  this
Registration  Statement  has  been  signed  by  the  following  persons  in  the
capacities and on the dates indicated.

Signature                            Title                    Date


/s/ Maximilian de Clara         Director and Principal    June 8, 2000
----------------------------    Executive Officer
Maximilian de Clara


/s/ Geert R. Kersten            Director, Principal       June 8, 2000
--------------------------      Financial Officer
Geert R. Kersten                and Chief Executive
                                Officer


--------------------------      Director
Alexander G. Esterhazy


/s/ John M. Jacquemin           Director                  June 8, 2000
-------------------------
John M. Jacquemin,

                                Director
Donald Hudson






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