CEL SCI CORP
S-3/A, 2000-08-11
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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As filed with the Securities and Exchange Commission on August 11, 2000.

                                                  Registration No 333-72415
                                                                  ---------

                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM S-3
                                 AMENDMENT NO. 3

                             Registration Statement
                                      Under
                           THE SECURITIES ACT OF 1933

                               CEL-SCI Corporation
                    ------------------ ---------------------
               (Exact name of registrant as specified in charter)

                                    Colorado
                            ------------ ----------
                 (State or other jurisdiction of incorporation)

                                               8229 Boone Blvd. #802
                                               Vienna, Virginia  22182
  84-09l6344                                     (703) 506-9460
(IRS Employer I.D.                 (Address, including zip code, and telephone
          Number)                   number including area of principal executive
                                    offices)

                                  Geert Kersten
                              8229 Boone Blvd. #802
                             Vienna, Virginia 22182
                                 (703) 506-9460
                   ------------------------ ----------------
          (Name and address, including zip code, and telephone number,
                   including area code, of agent for service)

         Copies of all communications, including all communications sent
                  to the agent for service, should be sent to:

                              William T. Hart, Esq.
                                  Hart & Trinen
                             1624 Washington Street
                             Denver, Colorado 80203
                                 (303) 839-0061

        APPROXIMATE DATE OF COMMENCEMENT OF PROPOSED SALE TO THE PUBLIC:
                 As soon as practicable after the effective date
                         of this Registration Statement

If the only securities  being registered on this Form are being offered pursuant
to dividend or interest reinvestment plans, please check the following box. [ ]



<PAGE>


If any of the  securities  being  registered on this Form are to be offered on a
delayed or continuous  basis  pursuant to Rule 415 under the  Securities  Act of
1933, other than securities offered only in connection with dividend or interest
reinvestment plans, check the following box. [X]

If this Form is filed to register additional securities for an offering pursuant
to Rule 462(b) under the Securities Act, please check the following box and list
the  Securities  Act  registration  statement  number of the  earlier  effective
registration for the same offering.  [ ]

If this Form is a  post-effective  amendment filed pursuant to Rule 462(c) under
the  Securities  Act,  check  the  following  box and  list the  Securities  Act
registration  statement number of the earlier effective  registration  statement
for the same offering. [ ]

If delivery  of the  prospectus  is  expected  to be made  pursuant to Rule 434,
please check the following box. [ ]
                           CALCULATION OF REGISTRATION FEE
--------------------------------------------------------------------------------


Title of each                          Proposed        Proposed
  Class of                              Maximum        Maximum
Securities           Securities        Offering       Aggregate      Amount of
  to be                 to be          Price Per      Offering     Registration
Registered           Registered         Unit (1)        Price         Fee (5)
-----------          ----------         --------

Common stock (2)         1,100,000        $2.50      $2,750,000       $726.00
Common stock (3)            50,000        $2.50         125,000         33.00
Common stock (4)           145,000        $2.50         362,500         96.10
                        ----------       ------      ----------    ----------

Total                    1,295,000                   $3,237,500       $855.00
                         =========                   ==========       =======



(1) Offering price computed in accordance with Rule 457(c).
(2) Shares of common stock  issuable  upon the exercise of Series A and Series B
    Warrants.  The Series A and Series B Warrants were issued in connection with
    the sale of CEL-SCI's Series D Preferred Stock.  Includes  additional shares
    which may be issued due to potential adjustments to Warrant exercise price.
(3) Shares of common stock issuable upon the exercise of Sales Agent's Warrants.
(4)  Shares of common  stock  issuable  upon the  exercise  options  granted  to
     investor relations consultants and another third party.
(5) A fee of $5,429 was paid upon the filing of this Registration Statement.

         Pursuant  to  Rule  416,  this  Registration  Statement  includes  such
indeterminate  number of  additional  securities as may be required for issuance
upon the exercise of the warrants or other options as a result of any adjustment
in the number of securities  issuable by reason of the anti-dilution  provisions
of the warrants or options.

         The registrant hereby amends this  Registration  Statement on such date
or dates as may be necessary to delay its  effective  date until the  registrant
shall file a further amendment which specifically  states that this Registration
Statement shall  thereafter  become effective in accordance with Section 8(a) of
the  Securities  Act of l933 or until the  Registration  Statement  shall become
effective on such date as the Commission,  acting pursuant to said Section 8(a),
may determine.


<PAGE>



PROSPECTUS
                               CEL-SCI CORPORATION
                                  Common Stock

    By means of this prospectus  CEL-SCI  Corporation  selling  shareholders are
offering to sell up to 1,295,000 shares of CEL-SCI's common stock.

      This prospectus offers securities which are speculative and involve a high
degree of risk.  Only  persons  who can afford to lose their  entire  investment
should  consider  purchasing  these  securities.  For a  description  of certain
important factors that prospective investors should consider, see "Risk Factors"
beginning on page 6 of this prospectus.

    Neither the  Securities  and Exchange  Commission  nor any state  securities
commission has approved or  disapproved  of these  securities or passed upon the
adequacy or accuracy of this prospectus. Any representation to the contrary is a
criminal offense.

      CEL-SCI's common stock is traded on the American Stock Exchange. On August
___,  2000 the closing  price of CEL-SCI's  common  stock on the American  Stock
Exchange was $_____.

                      The date of this prospectus is August ___, 2000



<PAGE>


                               PROSPECTUS SUMMARY

    THIS SUMMARY  SHOULD BE READ IN  CONJUNCTION  WITH,  AND IS QUALIFIED IN ITS
ENTIRETY  BY, THE MORE  DETAILED  INFORMATION  AND  APPEARING  ELSEWHERE IN THIS
PROSPECTUS.



CEL-SCI

      CEL-SCI Corporation was formed as a Colorado  corporation in 1983. CEL-SCI
is involved in the  research  and  development  of certain  drugs and  vaccines.
CEL-SCI  manufactures  MULTIKINE,  its first, and main product,  using CEL-SCI's
proprietary  cell  culture  technologies,   which  involve  a  combination,   or
"cocktail",   of  natural  human   interleukin-2  and  certain  lymphokines  and
cytokines.  CEL-SCI is testing  MULTIKINE  to  determine  if it is  effective in
improving the immune response of cancer patients.  CEL-SCI is testing its second
most   advanced   product,   HPG-30W,   to  determine  if  it  is  an  effective
vaccine/treatment  against  the AIDS  virus.  The third  technology  CEL-SCI  is
developing,  Ligand Epitope Antigen  Presentation  System  (LEAPS),  is a T-cell
modulation  technology  which  health  care  professionals  can use to  direct a
specific  immune  response  in persons  vaccinated  with  HGP-30W and to develop
potential  treatments and/or vaccines against various  diseases.  Present target
diseases are AIDS, herpes simplex,  malaria,  tuberculosis,  prostate cancer and
breast cancer.

      Before  human  testing  can begin  with  respect  to a drug or  biological
product, preclinical studies are conducted in laboratory animals to evaluate the
potential efficacy and the safety of a product. Human clinical studies generally
involve  a  three-phase  process.  The  initial  clinical  evaluation,  Phase I,
consists of administering  the product and testing for safe and tolerable dosage
levels.  Phase II trials  continue the  evaluation  of safety and  determine the
appropriate dosage for the product,  identify possible side effects and risks in
a larger group of subjects,  and provide  preliminary  indications  of efficacy.
Phase III trials  consist of testing  for  actual  clinical  efficacy  within an
expanded group of patients at geographically dispersed test sites.

         CEL-SCI  has  funded  the costs  associated  with the  clinical  trials
relating  to  CEL-SCI's   technologies,   research  expenditures  and  CEL-SCI's
administrative expenses with the public and private sales of shares of CEL-SCI's
common stock and borrowings from third parties, including affiliates of CEL-SCI.

         CEL-SCI  does not expect to develop  commercial  products  for  several
years, if at all. CEL-SCI has had operating  losses since its inception,  had an
accumulated  deficit  of  approximately  $(57,190,000)  at March 31,  2000,  and
expects to incur substantial losses for the foreseeable future.

    CEL-SCI's  executive offices are located at 8229 Boone Blvd.,  #802, Vienna,
Virginia 22182, and its telephone number is (703) 506-9460.


<PAGE>


                                  THE OFFERING

Securities Offered:

      By means of this prospectus  certain  shareholders are offering to sell up
to 1,285,000 shares of the common stock of CEL-SCI. CEL-SCI refers to the owners
of these shares as the selling shareholders in this prospectus.

Common                      Stock  Outstanding:  As of May 31, 2000, CEL-SCI had
                            20,439,209   shares  of  common   stock  issued  and
                            outstanding.  The number of outstanding  shares does
                            not give  effect to shares  which may be issued upon
                            the exercise and/or conversion of options,  warrants
                            or other convertible  securities held by the selling
                            shareholders  or  other  persons.  See  "Comparative
                            Share Data".

Risk                        Factors:  The purchase of the securities  offered by
                            this prospectus involves a high degree of risk. Risk
                            factors  include the lack of revenues and history of
                            loss,  need for additional  capital and need for FDA
                            approval.  See the "Risk  Factors"  section  of this
                            prospectus for additional Risk Factors.

AMEX Symbol:            CVM

Summary Financial Data

Statements of Operations
                             Six Months Ended        Years Ended September 30,
                              March 31, 2000          1999               1998
                                                      ----               ----

Investment Income and
  Other Revenues                  $135,848          $  469,518        $792,994

Expenses:
  Research and Development       2,487,290           4,461,051       3,833,854

Depreciation and Amortization      143,337             268,210         295,331

General and Administrative       2,067,469           3,230,982       3,106,492
                                 ---------           ---------       ---------

Net Loss                       (4,562,248)         $(7,490,725)    $(6,442,683)
                               ===========         ============    ============

Accretion of Preferred Stock           --                   --       1,980,000
                               -----------

Preferred Stock Dividends              --                   --              --
                               -----------      ---------------    ------------



<PAGE>


Net Loss attributable to
common stockholders           $(4,562,248)        $(7,490,725)    $(8,422,683)
                              ============        ============    ============

Loss per common share (basic)$        (0.25)     $      (0.52)   $     ( 0.74)
                             ===============     ===============  ============

Loss per common share (diluted)$      (0.25)   $        (0.52)   $      (0.74)
                               ===============   ===============  ============

Weighted average common
shares outstanding               18,071,192        14,484,352      11,379,437

Balance Sheets
                                                               September 30,
                             March 31, 2000              1999             1998
                             --------------              ----             ----

Working Capital               $15,864,508            $6,152,715     $12,926,014
Total Assets                   17,395,329             7,559,772      14,431,813
Current Liabilities               566,850               433,265         427,147
Long Term and Other Liabilities    28,321                28,321          29,382
Total Liabilities                 595,171               461,586         456,529
Shareholders' Equity           16,800,158             7,098,186      13,975,284

                                  RISK FACTORS

         Investors  should be aware that this offering  involves  certain risks,
including those described below, which could adversely affect the value of their
holdings of common stock. CEL-SCI does not make, nor has it authorized any other
person to make,  any  representation  about the future market value of CEL-SCI's
common stock. In addition to the other information contained in this prospectus,
the following factors should be considered carefully in evaluating an investment
in the shares offered by this prospectus

CEL-SCI Has Earned Only Limited Revenues and Has a History of Losses.
--------------------------------------------------------------------

         CEL-SCI  has had only  limited  revenues  since it was  formed in 1983.
Since the date of its formation and through March 31, 2000 CEL-SCI  incurred net
losses of  approximately  $(57,190,000).  During the years ended  September  30,
1997, 1998 and 1999 CEL-SCI  suffered losses of  $(8,189,458),  $(6,442,683) and
$(7,490,725)  respectively.  CEL-SCI has relied principally upon the proceeds of
public and private sales of securities to finance its activities to date. All of
CEL-SCI's  potential  products are in the early stages of  development,  and any
commercial sale of these products will be many years away. Accordingly,  CEL-SCI
expects to incur substantial losses for the foreseeable future.

         There can be no assurance  CEL-SCI will be  profitable.  At the present
time,  CEL-SCI intends to use available funds to finance  CEL-SCI's  operations.
Accordingly, while payment of dividends rests within the discretion of the Board
of Directors,  no common stock  dividends have been declared or paid by CEL-SCI.
CEL-SCI does not presently intend to pay dividends on its common stock and there
can be no assurance that common stock dividends will ever be paid.

<PAGE>

If  Cel-Sci  cannot  obtain  additional  capital,  Cel-Sci  may have to delay or
postpone  development and research  expenditures  which may influence  Cel-Sci's
ability to produce a timely and competitive product.

      Clinical and other studies  necessary to obtain approval of a new drug can
be time  consuming  and costly,  especially  in the United  States,  but also in
foreign countries.  The different steps necessary to obtain regulatory approval,
especially that of the Food and Drug  Administration,  involve significant costs
and may require  several  years to complete.  CEL-SCI  expects that it will need
additional  financing over an extended period of time in order to fund the costs
of future clinical  trials,  related  research,  and general and  administrative
expenses.  There  can be no  assurance  that  CEL-SCI  will be  able  to  obtain
additional funding from other sources.

If Cost Estimates for Clinical  Trials and Research Are Inaccurate  CEL-SCI Will
Require Additional Funding.

      CEL-SCI's  estimates of the costs  associated  with future clinical trials
and  research  may be  substantially  lower  than  the  actual  costs  of  these
activities.  If  CEL-SCI's  cost  estimates  are  incorrect,  CEL-SCI  will need
additional funding for its research efforts.

Any failure to obtain or any delay in obtaining  required  regulatory  approvals
may  adversely  affect  the  ability  of  potential   licensees  or  CEL-SCI  to
successfully market any products they may develop.

      Therapeutic agents, drugs and diagnostic products are subject to approval,
prior to general  marketing,  by the FDA in the United  States and by comparable
agencies  in  most  foreign   countries.   The  process  of  obtaining  FDA  and
corresponding  foreign approvals is costly and time consuming,  particularly for
pharmaceutical  products  such as those which might  ultimately  be developed by
CEL-SCI, VTI or its licensees, and there can be no assurance that such approvals
will be granted.  Also, the extent of adverse government regulations which might
arise from future legislative or administrative action cannot be predicted.

CEL-SCI  has,  at the present  time,  only one source of  multikine  and if this
source  could not,  for any  reason,  supply  CEL-SCI  with  Multikine,  CEL-SCI
estimates that it would take  approximately six to ten months to obtain supplies
of Multikine under an alternative manufacturing arrangement.

       CEL-SCI  has  an  agreement  with  an  unrelated   corporation   for  the
production,  until August 2000, of Multikine for research and testing  purposes.
CEL-SCI does not know what cost it would incur to obtain an  alternative  source
of supply.

There can be no assurance  that  CEL-SCI will achieve or maintain a  competitive
position  or that  other  technological  developments  will not cause  CEL-SCI's
proprietary technologies to become uneconomical or obsolete.

      The biomedical  field in which CEL-SCI is involved is undergoing rapid and
significant  technological  change.  The  successful  development of therapeutic
agents  from   CEL-SCI's

<PAGE>

compounds,  compositions and processes through CEL-SCI-financed research or as a
result  of  possible  licensing   arrangements  with   pharmaceutical  or  other
companies,  will depend on its ability to be in the  technological  forefront of
this field.

      Many  pharmaceutical and biotechnology  companies are developing  products
for the prevention or treatment of cancer and AIDS. Many of these companies have
substantial financial, research and development, and marketing resources and are
capable of providing  significant  long-term  competition either by establishing
in-house  research  groups  or by  forming  collaborative  ventures  with  other
entities.  In addition,  both smaller companies and non-profit  institutions are
active in research  relating to cancer and AIDS and are  expected to become more
active in the future.

CEL-SCI's Patents Might Not Protect CEL-SCI's Technology from Competitors.

      Certain aspects of CEL-SCI's  technologies are covered by U.S. and foreign
patents. In addition, CEL-SCI has a number of patent applications pending. There
is no assurance that the applications still pending or which may be filed in the
future will  result in the  issuance of any  patents.  Furthermore,  there is no
assurance as to the breadth and degree of  protection  any issued  patents might
afford  CEL-SCI.  Disputes may arise between  CEL-SCI and others as to the scope
and validity of these or other  patents.  Any defense of the patents could prove
costly and time  consuming and there can be no assurance that CEL-SCI will be in
a position, or will deem it advisable, to carry on such a defense. Other private
and public concerns, including universities, may have filed applications for, or
may have been issued,  patents and are expected to obtain additional patents and
other  proprietary  rights to  technology  potentially  useful or  necessary  to
CEL-SCI.  The scope and  validity of such  patents,  if any, the extent to which
CEL-SCI may wish or need to acquire the rights to such patents, and the cost and
availability  of such  rights are  presently  unknown.  Also,  as far as CEL-SCI
relies upon unpatented proprietary technology, there is no assurance that others
may not  acquire  or  independently  develop  the  same or  similar  technology.
CEL-SCI's  first  MULTIKINE  patent will expire in the year 2000.  Since CEL-SCI
does not know if it will ever be able to sell  MULTIKINE on a commercial  basis,
CEL-SCI  cannot  predict what effect the  expiration of this patent will have on
CEL-SCI.  Notwithstanding  the above,  CEL-SCI  believes  that trade secrets and
later issued patents will protect the technology  associated with Multikine past
the year 2000.

CEL-SCI's  Product  Liability  Insurance May Not Be Adequate to Protect  CEL-SCI
from Possible Losses.

      Although  CEL-SCI has product  liability  insurance  for Multikine and its
HGP-30 vaccine,  the successful  prosecution of a product liability case against
CEL-SCI could have a materially  adverse  effect upon its business if the amount
of any judgment exceeds CEL-SCI's insurance coverage.

The Loss of Management and Scientific Personnel Could Adversely Affect CEL-SCI.
-------------------------------------------------------------------------------

      CEL-SCI is dependent for its success on the continued  availability of its
executive  officers.  The loss of the  services  of any of  CEL-SCI's  executive
officers  could have an adverse

<PAGE>

effect on CEL-SCI's  business.  CEL-SCI does not carry key man life insurance on
any of its officers.  CEL-SCI's future success will also depend upon its ability
to attract and retain qualified scientific personnel.  There can be no assurance
that CEL-SCI will be able to hire and retain such necessary personnel.

Shares  Issuable  Upon the  Conversion  of  Options,  Warrants  and  Convertible
Securities May Depress the Price of CEL-SCI's Common stock.

      CEL-SCI  has issued  options to its  officers,  directors,  employees  and
consultants  which allow the holders to acquire  additional  shares of CEL-SCI's
common stock.  In some cases  CEL-SCI has agreed that,  at its expense,  it will
make appropriate filings with the Securities and Exchange Commission so that the
securities  issuable  upon the  exercise of the options  will be  available  for
public sale.  Such filings  could result in  substantial  expense to CEL-SCI and
could hinder future financings by CEL-SCI.

      Until the options  expire,  the holders will have an opportunity to profit
from any increase in the market price of CEL-SCI's common stock without assuming
the risks of ownership.  Holders of the options may exercise them at a time when
CEL-SCI  could  obtain  additional  capital on terms more  favorable  than those
provided by the  options.  The  exercise  of the options  will dilute the voting
interest of the owners of presently outstanding shares of CEL-SCI's common stock
and may adversely affect the ability of CEL-SCI to obtain additional  capital in
the future. The sale of the shares of common stock issuable upon the exercise of
the options could adversely affect the market price of CEL-SCI's stock.

         In December 1999 and January 2000, CEL-SCI sold 1,148,592 shares of its
common stock, plus Series A and Series B warrants,  to three private  investors.
The Series A warrants  permit the holders of the  warrants  to purchase  402,007
shares of  CEL-SCI's  common  stock at a price of  $2.925  per share at any time
prior to  December 8, 2002.  The Series B warrants  allow the  investors,  under
certain circumstances, to acquire additional shares of CEL-SCI's common stock at
a nominal price in the event:

o     The price of CEL-SCI's common stock falls below $2.4375 per share or

o  CEL-SCI  raises in excess of  $1,000,000 at a price which is below either the
   then prevailing market price of CEL-SCI's common stock or $2.4375 per share.

         In March  2000,  CEL-SCI  sold an  additional  1,026,666  shares of its
common  stock,  plus Series C and Series D warrants,  to the same three  private
investors.  The Series C warrants permit the holders of the warrants to purchase
413,334  shares of  CEL-SCI's  common stock at a price of $8.50 per share at any
time prior to March 15, 2003. The Series D warrants  allow the investors,  under
certain circumstances, to acquire additional shares of CEL-SCI's common stock at
a nominal price in the event:

o     The price of CEL-SCI's common stock falls below $6.52 per share or

<PAGE>


o  CEL-SCI  raises in excess of  $1,000,000 at a price which is below either the
   then prevailing market price of CEL-SCI's common stock or $6.52 per share.

      Since the price of CEL-SCI's  common stock has been  volatile in the past,
investors could experience  substantial dilution upon the exercise of the Series
B or Series D warrants  if there is a decline in the market  price of  CEL-SCI's
common stock. See "Comparative Share Data".

      The shares of common stock sold in the December  1999,  January 2000,  and
March 2000 private offering, as well as the shares of common stock issuable upon
the exercise of the Series A, B, C and D warrants,  are being offered for public
sale by means of this prospectus. The issuance of common stock upon the exercise
of the  Series A, B C and D  warrants,  as well as future  sales of such  common
stock, or the perception that such sales could occur, could adversely affect the
market price of CEL-SCI's common stock.

CEL-SCI  may be  required  to make  payments  to the  holders  of the  Series  B
warrants.

      In December 1999 and January 2000,  CEL-SCI sold  1,148,592  shares of its
common stock,  plus Series A and Series B warrants,  to three private  investors
for  $2,800,000.  The  Series  B  warrants  allow  the  holders,  under  certain
circumstances,  to acquire  additional  shares of  CEL-SCI's  common  stock at a
nominal  price in the event (i) the price of CEL-SCI's  common stock falls below
$2.44 per share prior to certain vesting dates, or (ii) CEL-SCI raises in excess
of $1,000,000 at a price which is below either the then prevailing  market price
of CEL-SCI's common stock or $2.44 per share.

      In March 2000,  CEL-SCI sold  1,026,666  shares of its common stock,  plus
Series C and  Series  D  warrants,  to the  same  three  private  investors  for
$7,700,000.  The  Series D  warrants  also  allow  the  holders,  under  certain
circumstances,  to acquire  additional  shares of  CEL-SCI's  common  stock at a
nominal  price in the event (i) the price of CEL-SCI's  common stock falls below
$7.50 per share prior to certain vesting dates, or (ii) CEL-SCI raises in excess
of $1,000,000 at a price which is below either the then prevailing  market price
of CEL-SCI's common stock or $7.50 per share.

      The actual number of shares issuable upon the exercise of the Series B and
Series D  warrants  (if any)  will  vary  depending  upon a number  of  factors,
including the price of CEL-SCI's common stock at certain dates.

      CEL-SCI's common stock trades on the American Stock Exchange. The rules of
the AMEX require a corporation,  the securities of which are listed on the AMEX,
to obtain  shareholder  approval if 20% or more of a corporation's  common stock
will be sold in a private  offering  and below the  greater of the book value or
market price of the corporation's common stock.

      For purposes of applying this particular rule to the Series B and Series D
warrants,  the AMEX will  consider  the  issuance  of any common  stock upon the
exercise of the Series B or Series D warrants to be a sale of  CEL-SCI's  common
stock at less than  market  price since the  exercise  price of the Series B and
Series D warrants is nominal.


<PAGE>


      Consequently,  the AMEX rule would prohibit CEL-SCI from issuing more than
3,400,297 shares of common stock as a result of the exercise of the Series B and
Series D warrants  unless  shareholder  approval is obtained for the issuance of
the additional shares.

      It is possible, depending upon the future market price of CEL-SCI's common
stock,  that more than 3,400,297 shares could be issued upon the exercise of the
Series B and Series D warrants.

      In order to avoid any violation of the AMEX rules relating to the issuance
of shares  below the market price of CEL-SCI's  common  stock,  the terms of the
Series B and Series D warrants provide that no more than 3,400,297 shares may be
issued  unless  CEL-SCI  obtains  shareholder  approval for the issuance of such
additional shares.

      If CEL-SCI  fails to obtain or elects not to obtain  shareholder  approval
for the issuance of the  additional  shares  CEL-SCI will be required to pay the
holders of the Series B and Series D warrants an amount equal to the then market
value of the shares which would  otherwise be issuable  upon the exercise of the
Series B or Series D warrants had shareholder approval been obtained.

The Market Price for CEL-SCI's Common Stock is Volatile.

         The market price of CEL-SCI's  common stock,  as well as the securities
of other biopharmaceutical and biotechnology  companies,  have historically been
highly volatile,  and the market has from time to time  experienced  significant
price and volume fluctuations that are unrelated to the operating performance of
particular  companies.  Factors  such as  fluctuations  in  CEL-SCI's  operating
results,  announcements of technological innovations or new therapeutic products
by CEL-SCI or its competitors,  governmental regulation,  developments in patent
or other  proprietary  rights,  public  concern  as to the  safety  of  products
developed by CEL-SCI or other  biotechnology and pharmaceutical  companies,  and
general market  conditions may have a significant  effect on the market price of
CEL-SCI's common stock.

                             COMPARATIVE SHARE DATA

         As of May 31, 2000, the shareholders of CEL-SCI owned 20,439,209 shares
of common stock. The following table illustrates the comparative stock ownership
of the present  shareholders  of CEL-SCI,  as compared to the  investors in this
offering, assuming all shares offered are sold.
                                               Number of          Note
                                                 Shares           Reference

Shares outstanding as of May 31, 2000        20,439,209

Shares issuable upon exercise of warrants     1,100,000            A
sold in December 1997 Private Offering

<PAGE>


Shares issuable upon exercise of sales           50,000            B
agent warrants

Shares issuable upon exercise of options        115,000            C
granted to financial consultants

Shares offered by selling shareholder            10,000            D

Shares which will be outstanding, assuming the 21,704,209
exercise of all warrants and options listed above

Percentage of CEL-SCI's common stock  represented 5.9% by shares offered by this
prospectus, assuming the exercise of all warrants listed above

      The number of shares  outstanding as of May 31, 2000 excludes shares which
may be issued upon the exercise and/or conversion of options, warrants and other
convertible securities previously issued by CEL-SCI. See table below.

Other Shares Which May Be Issued:
--------------------------------

         The following table lists  additional  shares of CEL-SCI's common stock
which may be  issued  as the  result of the  exercise  of  outstanding  options,
warrants or the conversion of other securities issued by CEL-SCI:

                                                  Number of           Note
                                                   Shares           Reference

   Shares issuable upon exercise of               402,007               E
   Series A warrants

   Shares issuable upon exercise of                    --               E
   Series B warrants

   Shares issuable upon exercise of               413,334               F
   Series C warrants

   Shares issuable upon exercise of             1,540,000               F
   Series D warrants

   Shares issuable upon exercise of                25,000               G
   sales agent warrants

   Shares issuable upon exercise of options     3,270,048               H
   and  warrants  granted to Company's
   officers, directors, employees, consultants,
   and third parties



<PAGE>

A.  In  December  1997,  CEL-SCI  sold  10,000  shares of its Series D Preferred
    Stock,  and  1,100,000   warrants,   to  ten  institutional   investors  for
    $10,000,000.  All Series D Preferred shares were subsequently converted into
    5,201,400  shares of CEL-SCI's  common  stock.  Warrants for the purchase of
    550,000  shares of common stock are  exercisable  at a price of $8.62 at any
    time prior to December 22, 2001. Warrants for the purchase of 550,000 shares
    of common  stock are  exercisable  at a price of $9.31 at any time  prior to
    December  22,  2001.  As of May 31,  2000  none  of the  warrants  had  been
    exercised.

B.  In connection with CEL-SCI's December l997 sale of Series D preferred shares
    and warrants Shoreline Pacific  Institutional  Finance,  the sales agent for
    such offering, received a commission plus warrants to purchase 50,000 shares
    of CEL-SCI's  common stock.  The sales agent  warrants are  exercisable at a
    price of $8.62 per share at any time prior to December 22, 2001.

C.  CEL-SCI has granted options for the purchase of an additional 115,000 shares
    of common stock to certain investor  relations  consultants in consideration
    for  services  provided to CEL-SCI.  The options are  exercisable  at prices
    ranging between $2.50 and $5.00 per share and expire between  September 2002
    and June 2003.

D.   These shares were issued to Mr.  Soresi in partial  settlement of a lawsuit
     brought by Mr. Soresi  against  CEL-SCI.  As a condition of the  settlement
     CEL-SCI agreed to register these shares for resale in the public market.

E.  In December  1999 and January  2000,  CEL-SCI sold  1,148,592  shares of its
    common  stock,  plus Series A and Series B  warrants,  to a group of private
    investors  for  $2,800,000.  The  Series A  warrants  allow the  holders  to
    purchase up to 402,007 shares of CEL-SCI's common stock at a price of $2.925
    per share at any time prior to December 8, 2002. The Series B warrants allow
    the holders,  under certain  circumstances,  to acquire additional shares of
    CEL-SCI's common stock at a nominal price in the event:

o    the price of CEL-SCI's  common stock falls below $2.4375 per share prior to
     certain fixed vesting dates, or
o    CEL-SCI raises in excess of $1,000,000 at a price which is below either the
     then  prevailing  market  price of  CEL-SCI's  common  stock or $2.4375 per
     share.

      The fixed vesting dates for the purposes of the Series B warrants are:

                                December 8, 2000
                                  June 8, 2001
                                December 8, 2001
                                  June 8, 2002
                                December 8, 2002

      Other vesting dates will occur when an extraordinary event occurs, such as
a change in the control of CEL-SCI, the bankruptcy or liquidation of CEL-SCI, or
the  failure  of  CEL-SCI's

<PAGE>

common  stock to be listed on the  American  Stock  Exchange,  the NASDAQ  Stock
Market or the NASDAQ SmallCap market.

      Upon the  occurrence of a vesting  date,  the  additional  shares (if any)
which  CEL-SCI will be required to issue to the holders of the Series B warrants
will be determined in accordance with the following formula:

            [(C x PA) / A]  -  C

C    = The number of shares purchased by the Series B warrant holder and not yet
     sold

            PA          = The Adjustment  Price from the  immediately  preceding
                        vesting date or, with respect to the first vesting date,
                        $2.4375.

A     =  Adjustment  price,  which is equal to the  lesser of  $2.4375,  or the
     average of the 10 lowest  closing  bid  prices of  CEL-SCI's  common  stock
     during the 30 trading days immediately preceding the vesting date.

      In addition to the  foregoing,  if CEL-SCI  raises in excess of $1,000,000
through the sale of common stock, or securities  convertible  into common stock,
at a price which is below either the then  prevailing  market price of CEL-SCI's
common  stock or $2.4375  per share,  then the  holders of the Series B warrants
will be entitled  to receive  additional  shares of  CEL-SCI's  common  stock in
accordance with the following formula:

            [(C x $2.4375) / D]  -  C

            C           = The number of shares purchased by the Series B warrant
                        holder and not yet sold on the date of the financing.

            D           = An amount  equal to the  lesser of the  average of the
                        closing bid prices of CEL-SCI's  common stock for the 10
                        trading  days  immediately  preceding  the  date  of the
                        financing,  or the price per share of the common  stock,
                        or common stock equivalent (as the case may be), sold in
                        the financing.

      The actual  number of shares  issuable  upon the  exercise of the Series B
warrants (if any) will vary  depending  upon a number of factors,  including the
price of CEL-SCI's  common stock at certain  dates.  Accordingly,  the number of
shares (if any) which may be issued  upon the  exercise of the Series B warrants
cannot be  determined  at this time.  However,  based  upon the market  price of
CEL-SCI's  common stock on May 31, 2000,  CEL-SCI would not be required to issue
any material  shares of its common stock if the Series B warrants were exercised
as of that date.

<PAGE>


F.  In March 2000,  CEL-SCI  sold  1,026,666  shares of its common  stock,  plus
    Series C and Series D warrants, to the same private investors referred to in
    Note E for  $7,700,000.  The Series C warrants allow the holders to purchase
    up to 413,334 shares of CEL-SCI's common stock at a price of $8.50 per share
    at any time  prior to March  21,  2003.  The  Series D  warrants  allow  the
    holders,  under  certain  circumstances,  to  acquire  additional  shares of
    CEL-SCI's common stock at a nominal price in the event:

o    the price of  CEL-SCI's  common  stock falls below $7.50 per share prior to
     certain fixed vesting dates, or
o    CEL-SCI raises in excess of $1,000,000 at a price which is below either the
     then prevailing market price of CEL-SCI's common stock or $7.50 per share.

      The fixed vesting dates for the purposes of the Series D warrants are:

                                 March 16, 2001
                               September 16, 2001
                                 March 16, 2002
                               September 16, 2002
                                 March 16, 2003

      Other vesting dates will occur when an extraordinary event occurs, such as
a change in the control of CEL-SCI, the bankruptcy or liquidation of CEL-SCI, or
the  failure  of  CEL-SCI's  common  stock to be  listed on the  American  Stock
Exchange, the NASDAQ Stock Market or the NASDAQ SmallCap market.

      Upon the  occurrence of a vesting  date,  the  additional  shares (if any)
which  CEL-SCI will be required to issue to the holders of the Series D warrants
will be determined in accordance with the following formula:

            [(C x PA) / A]  -  C

C    = The number of shares purchased by the Series D warrant holder and not yet
     sold

            PA          = The Adjustment  Price from the  immediately  preceding
                        vesting date or, with respect to the first vesting date,
                        $7.50.

A                        =  Adjustment  price,  which is equal to the lesser of
                        $6.52,  or the  average  of the 10  lowest  closing  bid
                        prices of  CEL-SCI's  common stock during the 30 trading
                        days immediately preceding the vesting date.

      In addition to the  foregoing,  if CEL-SCI  raises in excess of $1,000,000
through the sale of common stock, or securities  convertible  into common stock,
at a price which is below either the then  prevailing  market price of CEL-SCI's
common stock or $7.50 per share,  then the

<PAGE>

holders of the Series D warrants will be entitled to receive  additional  shares
of CEL-SCI's common stock in accordance with the following formula:

            [(C x $7.50) / D]  -  C

            C           = The number of shares purchased by the Series B warrant
                        holder and not yet sold on the date of the financing.

            D           = An amount  equal to the  lesser of the  average of the
                        closing bid prices of CEL-SCI's  common stock for the 10
                        trading  days  immediately  preceding  the  date  of the
                        financing,  or the price per share of the common  stock,
                        or common stock equivalent (as the case may be), sold in
                        the financing.

      The actual  number of shares  issuable  upon the  exercise of the Series D
warrants (if any) will vary  depending  upon a number of factors,  including the
price of CEL-SCI's  common stock at certain  dates.  Accordingly,  the number of
shares (if any) which may be issued  upon the  exercise of the Series D warrants
cannot be  determined  at this time.  However,  based  upon the market  price of
CEL-SCI's  common stock on May 31, 2000,  CEL-SCI would not be required to issue
1,540,000  shares of its common stock if the Series D warrants were exercised as
of that date.

G. In connection with CEL-SCI's December 1999 sale of common stock and warrants,
Reedland  Capital  Partners,  a division of Financial  West Group,  acted as the
sales agent for such  offering and received a commission of $125,000 plus Series
A warrants to purchase 25,000 shares of CEL-SCI's  common stock. The sales agent
warrants  are  exercisable  at a price of $2.925  per share at any time prior to
December  8, 2002.  The shares  issuable  upon the  exercise  of the sales agent
warrants are being  offered for sale to the public by means of this  prospectus.
See "Selling Shareholders".

H. The options are exercisable at prices ranging from $1.87 to $11.00 per share.
CEL-SCI may also grant options to purchase additional shares under its Incentive
Stock Option and Non-Qualified Stock Option Plans.

      The shares  referred to in Notes E, F, G and H are being  offered for sale
to the public by means of separate registration statements which have been filed
with the Securities and Exchange Commission.

                              SELLING SHAREHOLDERS

         In December 1997,  CEL-SCI sold 10,000 shares of its Series D preferred
stock, and 1,100,000 warrants,  to ten institutional  investors for $10,000,000.
All Series D preferred shares were subsequently  converted into 5,201,400 shares
of CEL-SCI's common stock. Warrants for the purchase of 550,000 shares of common
stock are  exercisable  at a price of $8.62 at any time  prior to  December  22,
2001.  Warrants  for  the  purchase  of  550,000  shares  of  common  stock  are
exercisable  at a price of $9.31 at any time prior to December 22,  2001.  As of
May 31, 2000 none

<PAGE>

of the warrants had been exercised. The shares issuable upon the exercise of the
warrants are being offered to the public by means of this prospectus.

         In  connection  with  CEL-SCI's  December  1997  offering  of  Series D
preferred stock and warrants, Shoreline Pacific Institutional Finance, the sales
agent for such  offering,  received a commission as well as warrants to purchase
50,000 shares of CEL-SCI's  common stock at $8.62 per share. The shares issuable
upon the  exercise  of the sales  agent's  warrants  are also being  offered for
public sale by means of this prospectus.

         This  prospectus  also  relates to the sale of up to 135,000  shares of
common stock issuable upon the exercise of certain options granted by CEL-SCI to
certain investor  relations  consultants and up to 10,000 shares of common stock
offered by a selling  shareholder.  The  options  were  issued by CEL-SCI to the
investor  relations  consultants  in  consideration  for  services  provided  to
CEL-SCI.  The options are  exercisable at prices ranging between $2.50 and $5.62
per share and expire between June 2000 and June 2003.

         The holders of the options  referred to above,  to the extent  exercise
the  warrants or options,  are  referred to in this  prospectus  as the "selling
shareholders". CEL-SCI will not receive any proceeds from the sale of the shares
by the selling shareholders.

         The names of the selling shareholders are:

                                            Shares
                                            Which
                                            May be
                                            Acquired                  Share
                                            Upon Ex-     Shares to    Owner-
                              Shares        ercise of    be Sold      ship
                             Beneficially   Warrants     in this      After
      Name                     Owned (1)    or Options   Offering (5) Offering
----------------             -----------    ----------   ------------ --------

KA Investments LDC                --        220,000 (1)   220,000        --

Olympus Securities, Ltd.          --        330,000 (1)   330,000 (4)    --

AG Super Fund International       --         11,000 (1)    11,000        --
  Partners, L.P.

Raphael, L.P.                     --         16,500 (1)    16,500        --

Baldwin Enterprises, Inc.         --         33,000 (1)    33,000        --

Nelson Partners                   --        220,000 (1)   220,000 (4)    --

Leonardo, L.P.                    --        115,500 (1)   115,500        --

<PAGE>


Ramius Fund, Ltd.                 --         33,000 (1)    33,000        --

AGR Halifax Fund, Ltd.            --        110,000 (1)   110,000        --

Gam Arbitrage Investments, Inc.   --         11,000 (1)    11,000        --

Shoreline Pacific Institutional   --         50,000 (2)    50,000        --
  Finance

The Fulton Group                  --         50,000 (3)    50,000        --

Daryll Strahll                    --          5,000 (3)     5,000        --

Waterton Group LLC                --         10,000 (3)    10,000        --

Jonathan Gelles                   --         50,000 (3)    50,000

Mark Soresi                   10,000             --        10,000

(1) Represents  shares  issuable  upon  the  exercise  of the  warrants  sold in
    December 1997 private offering.

(2) Represents shares issuable upon the exercise of the sales agent's warrants.

(3) Represents  shares  issuable upon exercise of options  issued as payment for
    assisting  CEL-SCI  with its  relationship  with  shareholders,  brokers and
    institutional investors.

(4) Citadel  Limited  Partnership  is the  managing  general  partner  of Nelson
    Partners  and  the  trading   manager  of  Olympus   Securities,   Ltd.  and
    consequently  has voting control and investment  discretion  over securities
    held by both Nelson and Olympus.  The ownership  information for Nelson does
    not include the shares owned by Olympus and the  ownership  information  for
    Olympus does not include the shares owned by Nelson.

(5) Assumes  all  shares  owned,  or  which  may be  acquired,  by  the  selling
    shareholders, are sold to the public by means of this prospectus.

Plan of Distribution

      The  selling  shareholders  and  any  of  their  pledgees,  assignees  and
successors-in-interest  may, from time to time,  sell any or all of their shares
of common stock on any stock exchange,  market or trading  facility on which the
shares  are traded or in private  transactions.  These  sales may be at fixed or
negotiated  prices.  The  selling  shareholders  may  use any one or more of the
following methods when selling shares:

o    ordinary brokerage transactions and transactions in which the broker-dealer
     solicits purchasers;

<PAGE>


o     block trades in which the broker-dealer will attempt to sell the shares as
      agent but may  position  and resell a portion of the block as principal to
      facilitate the transaction;
o    purchases by a broker-dealer  as principal and resale by the  broker-dealer
     for its account;
o    an exchange  distribution  in accordance  with the rules of the  applicable
     exchange;
o     privately negotiated transactions;
o     short sales;
o    broker-dealers may agree with the Selling  Stockholders to sell a specified
     number of such shares at a stipulated  price per share;
o    a combination of any such  methods of sale;  and
o    any other  method  permitted  pursuant to applicable law.

      The selling  shareholders  may also sell  shares  under Rule 144 under the
Securities Act, if available, rather than under this prospectus.

      The selling  shareholders  may also engage in short sales against the box,
puts and calls and other transactions in securities of CEL-SCI or derivatives of
CEL-SCI  securities  and may sell or  deliver  shares in  connection  with these
trades. The selling  shareholders may pledge their shares to their brokers under
the margin provisions of customer agreements.  If a selling shareholder defaults
on a margin loan, the broker may, from time to time,  offer and sell the pledged
shares.

      Broker-dealers  engaged by the selling  shareholders may arrange for other
brokers-dealers to participate in sales.  Broker-dealers may receive commissions
or discounts from the selling  shareholders  (or, if any  broker-dealer  acts as
agent  for the  purchaser  of  shares,  from the  purchaser)  in  amounts  to be
negotiated.  The  selling  shareholders  do not  expect  these  commissions  and
discounts to exceed what is customary in the types of transactions involved.

      The  selling  shareholders  and any  broker-dealers  or  agents  that  are
involved  in selling  the shares may be deemed to be  "underwriters"  within the
meaning of the Securities Act in connection with such sales. In such event,  any
commissions  received  by such  broker-dealers  or agents  and any profit on the
resale  of the  shares  purchased  by  them  may be  deemed  to be  underwriting
commissions or discounts under the Securities Act.

      CEL-SCI  is  required  to  pay  all  fees  and  expenses  incident  to the
registration of the shares,  including fees and  disbursements of counsel to the
selling  shareholders.  CEL-SCI has agreed to indemnify the selling shareholders
against certain losses, claims,  damages and liabilities,  including liabilities
under the Securities Act.

      CEL-SCI  has  advised  the  selling  shareholders  that in the  event of a
"distribution"  of the shares  owned by the selling  shareholder,  such  selling
shareholders, any "affiliated purchasers", and any broker/dealer or other person
who  participates  in such  distribution  may be  subject  to Rule 102 under the
Securities  Exchange Act of 1934 ("1934 Act") until their  participation in that
distribution  is  completed.  A  "distribution"  is  defined  in Rule  102 as an
offering of securities "that is distinguished from ordinary trading transactions
by the magnitude of the offering and the presence of special selling efforts and
selling  methods".  CEL-SCI has also advised the selling  shareholders that Rule
102 under the 1934 Act prohibits any "stabilizing bid" or "stabilizing


<PAGE>

purchase"  for the purpose of pegging,  fixing or  stabilizing  the price of the
common stock in connection  with this  offering.  Rule 101 makes it unlawful for
any person who is  participating  in a distribution to bid for or purchase stock
of the same class as is the subject of the distribution.

         CEL-SCI  has  agreed to  indemnify  the  selling  shareholders  and any
securities  broker/dealers who may be deemed to be underwriters  against certain
liabilities,  including  liabilities under the Securities Act as underwriters or
otherwise.

                            DESCRIPTION OF SECURITIES

Common Stock

         CEL-SCI is authorized to issue 100,000,000 shares of common stock, (the
"common stock").  Holders of common stock are each entitled to cast one vote for
each share held of record on all matters  presented to shareholders.  Cumulative
voting is not  allowed;  hence,  the  holders of a majority  of the  outstanding
common stock can elect all directors.

         Holders of common stock are  entitled to receive such  dividends as may
be declared by the Board of Directors  out of funds legally  available  therefor
and,  in the  event of  liquidation,  to share pro rata in any  distribution  of
CEL-SCI's  assets after  payment of  liabilities.  The board is not obligated to
declare a dividend.  It is not  anticipated  that  dividends will be paid in the
foreseeable future.

         Holders of common stock do not have  preemptive  rights to subscribe to
additional  shares if issued by CEL-SCI.  There are no  conversion,  redemption,
sinking  fund or  similar  provisions  regarding  the common  stock.  All of the
outstanding  shares of common stock are fully paid and non-assessable and all of
the shares of common  stock  offered as a  component  of the Units will be, upon
issuance, fully paid and non-assessable.

Preferred Stock

         CEL-SCI is authorized to issue up to 200,000 shares of preferred stock.
CEL-SCI's Articles of Incorporation  provide that the Board of Directors has the
authority to divide the preferred  stock into series and, within the limitations
provided  by  Colorado   statute,   to  fix  by  resolution  the  voting  power,
designations,  preferences, and relative participation,  special rights, and the
qualifications,  limitations  or  restrictions  of the  shares of any  series so
established.  As the Board of Directors has authority to establish the terms of,
and to issue, the preferred stock without  shareholder  approval,  the preferred
stock could be issued to defend against any attempted takeover of CEL-SCI.

Transfer Agent

     American Securities Transfer,  Inc., of Denver,  Colorado,  is the transfer
agent for CEL-SCI's common stock.



<PAGE>


                                     EXPERTS

         The financial statements as of September 30, 1999 and 1998 and for each
of the three  years in the period  ended  September  30,  1999  incorporated  by
reference in this prospectus from CEL-SCI's Annual Report on Form 10-K have been
audited  by  Deloitte & Touche  LLP,  independent  auditors,  as stated in their
report which are incorporated herein by reference, and have been so incorporated
in reliance  upon the report of such firm given upon their  authority as experts
in accounting and auditing.

                                 INDEMNIFICATION

         CEL-SCI's  Bylaws  authorize  indemnification  of a director,  officer,
employee or agent of CEL-SCI against expenses incurred by him in connection with
any action,  suit,  or  proceeding to which he is named a party by reason of his
having acted or served in such capacity, except for liabilities arising from his
own  misconduct or negligence in  performance  of his duty. In addition,  even a
director,  officer,  employee,  or agent of  CEL-SCI  who was found  liable  for
misconduct  or  negligence  in the  performance  of his  duty  may  obtain  such
indemnification  if, in view of all the  circumstances  in the case,  a court of
competent jurisdiction  determines such person is fairly and reasonably entitled
to indemnification. Insofar as indemnification for liabilities arising under the
Securities  Act of 1933 may be  permitted  to  directors,  officers,  or persons
controlling  CEL-SCI  pursuant  to the  foregoing  provisions,  CEL-SCI has been
informed that in the opinion of the  Securities  and Exchange  Commission,  such
indemnification  is  against  public  policy  as  expressed  in the  Act  and is
therefore unenforceable.

                             ADDITIONAL INFORMATION

         CEL-SCI is subject to the  requirements of the Securities  Exchange Act
of l934 and is required to file reports,  proxy statements and other information
with the Securities and Exchange Commission.  Copies of any such reports,  proxy
statements and other  information filed by CEL-SCI can be read and copied at the
Commission's Public Reference Room at 450 Fifth Street, N.W., Washington,  D.C.,
20549.  The  public  may  obtain  information  on the  operation  of the  Public
Reference  Room by calling the  Commission  at  1-800-SEC-0330.  The  Commission
maintains  an  Internet  site  that  contains  reports,  proxy  and  information
statements, and other information regarding CEL-SCI. The address of that site is
http://www.sec.gov.

         CEL-SCI will provide,  without charge, to each person to whom a copy of
this prospectus is delivered,  including any beneficial  owner, upon the written
or  oral  request  of  such  person,  a copy  of  any  or  all of the  documents
incorporated by reference below (other than exhibits to these documents,  unless
the exhibits are specifically  incorporated by reference into this  prospectus).
Requests should be directed to:

                               CEL-SCI Corporation
                             8229 Boone Blvd., #802
                             Vienna, Virginia 22182
                                 (703) 506-9460

<PAGE>


         The  following   documents   filed  with  the   Commission  by  CEL-SCI
(Commission   File  No.  0-11503)  are   incorporated  by  reference  into  this
prospectus:

(1) CEL-SCI's Annual Report on Form 10-K for the fiscal year ended September 30,
1999.

(2) CEL-SCI's  Quarterly Reports (unaudited) on Form 10-Q for the quarters ended
    December 31, 1999 and March 31, 2000.

(3)  CEL-SCI's  Proxy  Statement  relating to the March 17,  2000  shareholders'
meeting.

         All documents filed with the Commission by CEL-SCI pursuant to Sections
13(a),  13(c),  14 or 15(d) of the Exchange Act  subsequent  to the date of this
prospectus  and prior to the  termination of this offering shall be deemed to be
incorporated  by  reference  into  this  prospectus  and  to be a part  of  this
prospectus  from  the  date of the  filing  of  such  documents.  Any  statement
contained in a document  incorporated  or deemed to be incorporated by reference
shall be deemed to be modified or superseded for the purposes of this prospectus
to  the  extent  that  a  statement  contained  in  this  prospectus  or in  any
subsequently  filed  document which also is or is deemed to be  incorporated  by
reference  in this  prospectus  modifies  or  supersedes  such  statement.  Such
statement so modified or superseded  shall not be deemed,  except as so modified
or superseded, to constitute a part of this prospectus.

         CEL-SCI  has  filed  with the  Securities  and  Exchange  Commission  a
Registration  Statement  under the  Securities  Act of l933,  as  amended,  with
respect to the securities  offered by this prospectus.  This prospectus does not
contain all of the  information  set forth in the  Registration  Statement.  For
further  information with respect to CEL-SCI and such  securities,  reference is
made  to  the  Registration  Statement  and  to  the  exhibits  filed  with  the
Registration  Statement.  Statements  contained  in  this  prospectus  as to the
contents  of any  contract  or  other  documents  are  summaries  which  are not
necessarily complete, and in each instance reference is made to the copy of such
contract or other  document filed as an exhibit to the  Registration  Statement,
each such  statement  being  qualified  in all respects by such  reference.  The
Registration  Statement  and  related  exhibits  may  also  be  examined  at the
Commission's internet site.



<PAGE>


         No dealer  salesman  or other  person has been  authorized  to give any
information or to make any  representations,  other than those contained in this
prospectus.  Any information or representation  not contained in this prospectus
must not be relied upon as having been  authorized by CEL-SCI.  This  prospectus
does not constitute an offer to sell, or a solicitation  of an offer to buy, the
securities  offered hereby in any state or other  jurisdiction  to any person to
whom it is unlawful to make such offer or solicitation.  Neither the delivery of
this  prospectus nor any sale made  hereunder  shall,  under any  circumstances,
create an  implication  that there has been no change in the  affairs of CEL-SCI
since the date of this prospectus.




                                TABLE OF CONTENTS

                                                                      Page
Prospectus Summary................................                      5
Risk Factors......................................                      9
Comparative Share Data............................                     12
Selling Shareholders..............................                     15
Description of Securities.........................                     19
Experts...........................................                     20
Indemnification...................................                     20
Additional Information............................                     21

                                 --------------
                                  Common Stock

                               CEL-SCI CORPORATION

                                   PROSPECTUS








<PAGE>


                                     PART II
                     Information Not Required in Prospectus


Item 14.  Other Expenses of Issuance and Distribution

             SEC Filing Fee                                     $  5,429
             Blue Sky Fees and Expenses                            2,000
             Printing and Engraving Expenses                       2,000
             Legal Fees and Expenses                              10,000
             Accounting Fees and Expenses                          3,000
             Miscellaneous Expenses                                2,571
                                                                --------
                  TOTAL                                          $25,000
                                                                 =======

             All expenses other than the S.E.C. filing fees are estimated.

Item 25.  Indemnification of Officers and Directors.
          -----------------------------------------

         It is provided by Section  7-109-102 of the Colorado  Revised  Statutes
and  CEL-SCI's  Bylaws that CEL-SCI may  indemnify  any and all of its officers,
directors,  employees  or agents or former  officers,  directors,  employees  or
agents,   against  expenses  actually  and  necessarily  incurred  by  them,  in
connection  with  the  defense  of any  legal  proceeding  or  threatened  legal
proceeding,  except as to matters in which such persons  shall be  determined to
not have acted in good faith and in the best interest of CEL-SCI.

Item 16.  Exhibits

3(a) Articles of Incorporation          Incorporated
                                        by reference to Exhibit 3(a)of CEL-SCI's
                                        combined  Registration Statement on Form
                                        S-1 and  Post-Effective  Amendment
                                        ("Registration   Statement"),
                                        Registration Nos. 2-85547-D and 33-7531.

 (b) Amended Articles                   Incorporated   by  reference  to
                                        Exhibit 3(a) of CEL-SCI's  Registration
                                        Statement on Form S-1, Registration Nos.
                                        2-85547-D and 33-7531.

 (c) Amended Articles                   Filed as Exhibit 3(c) to CEL-SCI's
    (Name change only)                  Registration  Statement  on  Form  S-1
                                        Registration Statement (No. 33-34878).

 (d) Bylaws                             Incorporated by reference  to  Exhibit
                                        3(b) of CEL-SCI's Registration Statement
                                        on Form S-1, Registration Nos. 2-85547-D
                                        and 33-7531.



<PAGE>


4(a)  Specimen copy of                 Incorporated by reference to Exhibit 4(a)
      Stock Certificate                of the Company's Registration Statement
                                       on Form S-1, Registration Nos. 2-85547-D
                                       and 33-7531.

5.    Opinion of Counsel               Previously filed.

10(e) Employment Agreement with         Filed with Amendment Number 1 to the
      Geert Kersten                     Company's Registration Statement on Form
                                        S-1 (Commission File Number 33-43281).

10(f) Securities  Purchase  Agreement     Incorporated  by reference to Exhibit
      (without Exhibits and Schedules)    4.1 filed with Report on Form 8-K
      pertaining to sale of Series D      dated December 22, 1997.
      Preferred Stock

10(g) Form of Common Stock Purchase    Incorporated  by reference to Exhibit 4.3
      Warrant sold with shares of      filed with Report on Form 8-K dated
       Series D Preferred Stock        December 22, 1997.

10(h) Registration Rights Agreement    Incorporated  by reference to Exhibit 4.4
      Pertaining to Series D Preferred  filed  with  Report on Form 8-K dated
      Stock and Warrants                 December 22, 1997.

23(a) Consent of Hart & Trinen            ______________________________________

    (b)  Consent of Deloitte & Touche, LLP


Item 17. Undertakings.
         ------------

         The undersigned Registrant hereby undertakes:

         (1) To file, during any period in which offers or sales are being made,
a post-effective amendment to this Registration Statement.

     (i)  To  include  any  prospectus  required  by  Section  l0(a)(3)  of  the
Securities Act of l933;

              (ii) To  reflect  in the  prospectus  any facts or events  arising
after the  effective  date of the  Registration  Statement  (or the most  recent
post-effective  amendment  thereof)  which,  individually  or in the  aggregate,
represent a fundamental  change in the information set forth in the Registration
Statement;







<PAGE>


              (iii)To include any material  information with respect to the plan
of distribution not previously  disclosed in the  Registration  Statement or any
material change to such  information in the  Registration  Statement,  including
(but not limited to) any addition or deletion of a managing underwriter.

         (2) That,  for the  purpose  of  determining  any  liability  under the
Securities Act of l933, each such post-effective amendment shall be deemed to be
a new registration statement relating to the securities offered therein, and the
offering of such  securities at that time shall be deemed to be the initial bona
fide offering thereof.

         (3) To remove from registration by means of a post-effective  amendment
any of the securities being registered which remain unsold at the termination of
the offering.

         Insofar as indemnification for liabilities arising under the Securities
Act of l933 may be permitted to directors,  officers and controlling  persons of
the  Registrant,  the  Registrant  has been  advised  that in the opinion of the
Securities and Exchange Commission such indemnification is against public policy
as expressed in the Act and is,  therefore,  unenforceable.  In the event that a
claim for  indemnification  against such liabilities  (other than the payment by
the  Registrant  of  expenses  incurred  or  paid  by  a  director,  officer  or
controlling  person of the Registrant in the  successful  defense of any action,
suit or proceeding) is asserted by such director,  officer or controlling person
in connection with the securities being registered,  the Registrant will, unless
in the  opinion  of its  counsel  the matter  has been  settled  by  controlling
precedent, submit to a court of appropriate jurisdiction the question of whether
such  indemnification by it is against public policy as expressed in the Act and
will be governed by the final adjudication of such issue.




<PAGE>



                                POWER OF ATTORNEY

         The  registrant  and each person whose  signature  appears below hereby
authorizes the agent for service named in this Registration Statement, with full
power to act alone,  to file one or more  amendments  (including  post-effective
amendments)  to this  Registration  Statement,  which  amendments  may make such
changes  in  this  Registration  Statement  as  such  agent  for  service  deems
appropriate,  and the Registrant and each such person hereby appoints such agent
for service as  attorney-in-fact,  with full power to act alone, to exe- cute in
the name and in behalf of the Registrant and any such person,  individually  and
in each  capacity  stated  below,  any  such  amendments  to  this  Registration
Statement.

                                   SIGNATURES

         Pursuant  to the  requirements  of the  Securities  Act  of  l933,  the
Registrant certifies that it has reasonable grounds to believe that it meets all
the  requirements  for filing on Form S-3 and has duly caused this  Registration
Statement  to be  signed  on its  behalf  by  the  undersigned,  thereunto  duly
authorized,  in the City of Vienna, State of Virginia, on the 4th day of August,
2000.

                               CEL-SCI CORPORATION

                                       By:    /s/ Maximilian de Clara
                                            -----------------------------
                                              MAXIMILIAN DE CLARA, PRESIDENT

         Pursuant  to the  requirements  of the  Securities  Act of  l933,  this
Registration  Statement  has  been  signed  by  the  following  persons  in  the
capacities and on the dates indicated.

Signature                             Title                    Date

 /s/ Maximilian de Clara         Director and Principal     August 4, 2000
--------------------------       Executive Officer
Maximilian de Clara


 /s/ Geert Kersten               Director, Principal        August 4, 2000
--------------------------       Financial Officer and
Geert R. Kersten                 Chief Executive Officer


 /s/ Alexander G. Esterhazy      Director                   August 4, 2000
-----------------------------
Alexander G. Esterhazy


 /s/ John M. Jacquemin           Director                   August 4, 2000
----------------------------
John M. Jacquemin

Donald Hudson                    Director




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