ALLIANCE MORTGAGE SECURITIES INCOME FUND INC
485B24E, 1995-02-24
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                                                 File No. 2-85921


                     Securities and Exchange Commission
                           Washington, D.C.  20549
                                                           

                                  FORM N-1A

           REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933

                         Pre-Effective Amendment No.

                       Post-Effective Amendment No. 22

                                   and/or

      REGISTRATION STATEMENT UNDER THE INVESTMENT COMPANY ACT OF 1940 

                                Amendment No.
                                                              

               ALLIANCE MORTGAGE SECURITIES INCOME FUND, INC.
             1345 Avenue of the Americas, New York, N.Y.  10105
                               (800) 221-5672
                                                                

                            EDMUND P. BERGAN, JR.
                      Alliance Capital Management L.P.
             1345 Avenue of the Americas, New York, N.Y.  10105
                   (Name and address of Agent for Service)
                                                          

                      Calculation of Registration Fee:

Title of 
Securities                 Proposed Maximum  Proposed            Amount of 
  Being      Amount Being  Offering Price    Maximum Aggregate   Registration
Registered    Registered      Per Unit *     Offering Price **       Fee     
__________   ____________  _______________   ________________    ____________
Common
Stock $.01     76,059,056       $8.63             $500,000          $172.40
par value 

                 * Estimated solely for the purpose of determining the amount
of the registration fee based on the net asset value per share of the
Registrant's Common Stock on February 14, 1995.



<PAGE>

                ** The calculation of the maximum aggregate offering price is
made pursuant to Rule 24e-2(a) under the Investment Company Act of 1940 and is
based on the following:  the total amount of securities redeemed or
repurchased during the fiscal year ended December 31, 1994 was 98,075,093
shares, 22,073,974 of which was previously used for reduction pursuant to Rule
24f-2 or Rule 24e-2(a) and 76,001,119 shares, of which are being so used in
this Amendment.

It is proposed that this filing will become effective (check appropriate box)

                 X immediately upon filing pursuant to paragraph (b)
                   on (date) pursuant to paragraph (b)
                   60 days after filing pursuant to paragraph (a)
                   on (date) pursuant to paragraph (a) of rule 485.

EXHIBIT:  Opinion of Messrs. Seward & Kissel



<PAGE>

                               Alliance Fund Distributors, Inc.
                                    1345 Avenue of the Americas 
                                    New York, New York  10105

                                    George O. Martinez
                                    Vice President and
                                    Associate General Counsel
                                    (212) 969-2156


                                    February 24, 1995




Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C. 20549

             Re:  Alliance Mortgage Securities Income Fund, Inc.
                          (File No. 2-85921)                 
            ---------------------------------------------------- 

Dear Sirs:

       We have enclosed the following documents for filing on behalf of
Alliance Mortgage Securities Income Fund, Inc., a Maryland corporation (the
"Fund"):

       1.    A copy of Post-Effective Amendment No. 22 to the Fund's
             Registration Statement (File No. 2-85921) under the Securities
             Act of l933, one of which contains the required manual signatures
             of officers and directors of the Fund and five of which are
             marked to indicate changes.

      2.     Opinion of counsel to the Fund as to the shares to be registered,
             which is filed as an Exhibit to the enclosed Amendment.

      3.     Representation of counsel pursuant to paragraph (b) of Rule 485.



<PAGE>

 
      4.     Certified check in the amount of $172.40 calculated in accordance
             with Rule 457 under the Securities Act of l933 and filed pursuant
             to Rule 24e-2 under the Investment Company Act of l940.

      The only purpose of this Amendment is to register additional shares of
the Fund's common stock in accordance with Rule 24e-2 under the Investment
Company Act of l940.

      Please acknowledge receipt of this filing by stamping the enclosed copy
of this letter and returning it in the self-addressed envelope provided.

                                    Sincerely,



                                    /s/ George O. Martinez



<PAGE>


                                Alliance Fund Distributors, Inc.
                                    1345 Avenue of the Americas 
                                    New York, New York  10105

                                    George O. Martinez
                                    Vice President and
                                    Associate General Counsel
                                    (212) 969-2156


                                    February 24, 1995




Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C.  20549


         Re:  Alliance Mortgage Securities Income Fund, Inc.
                            (File No. 2-85921)              
              -----------------------------------------------

Dear Sirs:

     I have acted as counsel to Alliance Mortgage Securities Income Fund, Inc.
(the "Fund") in connection with the preparation of Post-Effective Amendment
No. 22 to the Fund's Form N-1A Registration Statement.

     In my view, the above-described Amendment does not contain disclosures
which would render it ineligible to become effective pursuant to paragraph (b)
of Rule 485 under the Securities Act of 1933.

                                    Sincerely,


                                     /s/ George O. Martinez



<PAGE>

                                 SIGNATURE

         Pursuant to the requirements of the Securities Act of 1933 and the
Investment Company Act of 1940, the Registrant certifies that it meets all
of the requirements for effectiveness of this Amendment to its Registration
Statement pursuant to Rule 485(b) under the Securities Act of 1933 and has
duly caused this Amendment to its Registration Statement to be signed on
its behalf by the undersigned, thereunto duly authorized, in the City of
New York and State of New York, on the 24th day of February, 1995.

                                  ALLIANCE MORTGAGE SECURITIES 
                                    INCOME FUND, INC.

                                  by /s/    John D. Carifa
                                       ------------------------
                                              President

    Pursuant to the requirements of the Securities Act of l933, this
Amendment to the Registration Statement has been signed below by the
following persons in the capacities and on the dates indicated:

    SIGNATURE                           TITLE              DATE

1)     Principal Executive Officer

    /s/  John D. Carifa              President       February  24, 1995
         ------------------

2)     Principal Financial and
  Accounting Officer

     /s/  Mark D. Gersten       Treasurer and Chief  February  24, 1995
          ---------------       Financial Officer

3)  ALL OF THE DIRECTORS

  Ruth S. Block
  John D. Carifa
  David H. Dievler
  James R. Greene
  James M. Hester
  Clifford L. Michel
  Eugene F. O'Neil
  Robert C. White

by /s/   Edmund P. Bergan, Jr.  (Attorney-in-fact)   February 24, 1995
         ---------------------



<PAGE>

                                  February 24, 1995




Alliance Mortgage Securities
  Income Fund, Inc. 
1345 Avenue of the Americas
New York, New York 10105

Dear Sirs:

         We have acted as counsel for Alliance Mortgage
Securities Income Fund, Inc., a Maryland corporation (the
"Company"), in connection with the registration of an
additional 76,059,056 shares of common stock, par value $.01
per share, of the Company under the Securities Act of 1933,
as amended (the "Act").

         As counsel for the Company, we have participated in
the preparation of Post-Effective Amendment No. 22 to the
Company's Registration Statement on Form N-1A under the Act
(File No. 2-85921) relating to such additional shares and
have examined and relied upon corporate records of the
Company and other documents and certificates as to factual
matters as we have deemed to be necessary to render the
opinion set forth below.

         Based on that examination we are of the opinion
that the 76,059,056 additional shares of common stock of the
Company being registered by Post-Effective Amendment No. 22
to the Company's Registration Statement are duly authorized
and unissued shares, and when such shares have been duly
sold, issued and paid for as contemplated in the Company's
Prospectus forming a part of its Registration Statement
under the Act, such shares will have been validly and
legally issued (assuming that none of such shares is sold at
a time when such sale would cause the Company to have
outstanding more than the number of shares of common stock
authorized to be issued by the Company's Articles of
Incorporation) and will be fully paid and non-assessable
shares of common stock of the Company under the laws of the
State of Maryland (assuming that the sale price of each
share is not less than the par value thereof).

         Our opinion above stated is expressed as members of
the bar of the State of New York.

         We hereby consent to the filing of this opinion
with the Securities and Exchange Commission as an exhibit to



<PAGE>

above-referenced Post-Effective Amendment No. 22 to the
Company's Registration Statement.

                                  Very truly yours,


                                  /s/  Seward & Kissel



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