SCIOS INC
DEF 14A, 1997-04-01
DRUGS, PROPRIETARIES & DRUGGISTS' SUNDRIES
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<PAGE>

                            SCHEDULE 14A INFORMATION


                  Proxy Statement Pursuant to Section 14(a) of
            the Securities Exchange Act of 1934 (Amendment No.    )

    Filed by the Registrant /X/
    Filed by a Party other than the Registrant / /

    Check the appropriate box:
    / /    Preliminary Proxy Statement
    / /    Confidential, for Use of the Commission Only (as permitted by Rule
             14a-6(e)(2))
    /X/    Definitive Proxy Statement
    / /    Definitive Additional Materials
    / /    Soliciting  Material  Pursuant  to  Section  240.14a-11(c)  or
               Section 240.14a-12

                          SCIOS INC
- --------------------------------------------------------------------------------
                (Name of Registrant as Specified In Its Charter)

- --------------------------------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):

/X/  No fee required.
/ /  Fee  computed  on   table  below   per  Exchange   Act  Rules   14a-6(i)(1)
     and 0-11.
     1) Title of each class of securities to which transaction applies:
        ------------------------------------------------------------------------
     2) Aggregate number of securities to which transaction applies:
        ------------------------------------------------------------------------
     3) Per unit  price  or  other  underlying  value  of  transaction  computed
        pursuant  to  Exchange  Act Rule 0-11 (Set forth the amount on which the
        filing fee is calculated and state how it was determined):
        ------------------------------------------------------------------------
     4) Proposed maximum aggregate value of transaction:
        ------------------------------------------------------------------------
     5) Total fee paid:
        ------------------------------------------------------------------------
/ /  Fee paid previously with preliminary materials.
/ /  Check box if any part of the fee is offset as provided  by  Exchange  Act
     Rule  0-11(a)(2)  and identify the filing for which the  offsetting fee was
     paid  previously.  Identify the previous filing by  registration  statement
     number, or the Form or Schedule and the date of its filing.
     1) Amount Previously Paid:
        ------------------------------------------------------------------------
     2) Form, Schedule or Registration Statement No.:
        ------------------------------------------------------------------------
     3) Filing Party:
        ------------------------------------------------------------------------
     4) Date Filed:
        ------------------------------------------------------------------------

<PAGE>
                                     [LOGO]


                                   Scios Inc.
                              2450 Bayshore Parkway
                         Mountain View, California 94043

                                   ----------

                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                              Tuesday, May 13, 1997
                                   10:00 a.m.
                                   ----------

To the Stockholders:

         NOTICE IS HEREBY GIVEN that the Annual Meeting of Stockholders of Scios
Inc., a Delaware  corporation  (the  "Company"),  will be held at the  Company's
principal executive offices,  2450 Bayshore Parkway,  Mountain View,  California
94043,  at 10:00 a.m. on Tuesday,  May 13,  1997,  to consider  and act upon the
following matters:

         (1)      To elect directors of the Company.

         (2)      To approve amendments to the Company's 1992 Equity Incentive
                  Plan.

         (3)      To ratify the selection of Coopers & Lybrand  L.L.P.  as the
                  Company's  independent  auditors for fiscal 1997.

         (4)      To  act  upon  such  other  matters,   including   stockholder
                  proposals,  that may  properly  come before the meeting or any
                  adjournment or postponement of the meeting.

         Only  stockholders of record at the close of business on March 17, 1997
will be entitled to notice of and to vote at this meeting and any adjournment or
postponement thereof.

                                     By Order of the Board of Directors

                                     JOHN H. NEWMAN
                                     Secretary


Mountain View, California
March 31, 1997

YOUR VOTE IS IMPORTANT. WHETHER OR NOT YOU EXPECT TO ATTEND THIS MEETING,
PLEASE MARK,  DATE AND SIGN THE  ENCLOSED  PROXY  AND MAIL IT  PROMPTLY
IN THE ENCLOSED ENVELOPE. NO POSTAGE IS REQUIRED IF MAILED IN THE UNITED STATES.


<PAGE>


                                   Scios Inc.
                              2450 Bayshore Parkway
                         Mountain View, California 94043
                                   ----------

                                 Proxy Statement
                         Annual Meeting of Stockholders
                                  May 13, 1997


General

         This Proxy  Statement  is solicited on behalf of the Board of Directors
of Scios Inc., a Delaware corporation (the "Company" or "Scios"), for use at its
Annual Meeting of Stockholders to be held at the Company's  principal  executive
offices,  2450 Bayshore Parkway,  Mountain View, California 94043, at 10:00 a.m.
on  Tuesday,  May 13,  1997,  and at any  adjournment  or  postponement  of that
meeting.  The approximate mailing date for this Proxy Statement and the enclosed
proxy is March 31, 1997.

         The Board of  Directors  has fixed the close of  business  on March 17,
1997 as the record date for the  determination of stockholders  entitled to vote
at the Annual  Meeting.  At that time,  there were  35,833,923  shares of Common
Stock issued and outstanding. In addition, there were 12,632 shares of Nonvoting
Series A Preferred Stock issued and outstanding.

Voting

         Each share of Common Stock issued and outstanding on the record date is
entitled to one vote. The Nonvoting  Series A Preferred Stock is not entitled to
vote.  The  proxy  holders  will  vote  all  proxies  in  accordance   with  the
instructions  contained in the proxy and, if no choice is  specified,  the proxy
holders will vote in favor of the proposals to elect  directors,  to approve the
amendment  of the  Company's  1992  Equity  Incentive  Plan  and to  ratify  the
selection  of  auditors,  and against the  stockholder  proposals.  An automated
system  administered by the Company's  transfer agent  tabulates the votes.  The
presence at the Annual Meeting in person or by proxy of a majority of the shares
outstanding as of the record date will constitute a quorum. For quorum purposes,
abstentions and broker  non-votes are each included in the  determination of the
number of shares  present  and  voting.  Each  matter is  tabulated  separately.
Abstentions are counted in tabulations of the votes cast on proposals  presented
to  stockholders,  whereas  broker  non-votes are not counted for any purpose in
determining whether a proposal has been approved.

Revocability of Proxies

         Any person giving a proxy in the form accompanying this Proxy Statement
has the power to revoke it at any time before its exercise. It may be revoked by
filing with the  Secretary of the Company an  instrument of revocation or a duly
executed proxy bearing a later date. It also may be revoked by attendance at the
meeting and  election  to vote in person.  Attendance  at the  meeting  will not
itself revoke a proxy.

Solicitation

         The  Company  will  bear  the  entire  cost of  preparing,  assembling,
printing  and  mailing  this Proxy  Statement,  the  accompanying  proxy and any
additional  material  which may be  furnished  to  stockholders  by the Company.
Copies of  solicitation  material will be furnished  without charge to brokerage
houses, fiduciaries and custodians to forward to beneficial owners of stock held
in their names. The solicitation of proxies will be made by the use of the mails
and  through   direct   communication   with  certain   stockholders   or  their
representatives  by officers,  directors and employees of the Company,  who will
receive no  additional  compensation  therefor.  In  addition,  the  Company may
determine to engage D.F. King & Co., Inc. or another proxy  solicitor to solicit
proxies  and, if it does so, the  Company  will pay the  standard  fee for these
services, which is estimated to be approximately $6,000.

<PAGE>
                                   PROPOSAL 1
                              ELECTION OF DIRECTORS

         A Board of seven (7) Directors  will be elected at the Annual  Meeting.
The term of office of each person  elected as a Director will continue until the
next Annual  Meeting or until a successor  has been  elected.  Unless  otherwise
instructed,  the proxy  holders  will vote the proxies  received by them for the
seven nominees of the Board of Directors named below,  all of whom are presently
Directors of the Company.  The candidates  receiving a plurality of the votes of
the shares  present in person or by proxy at the  meeting  and  entitled to vote
will be  elected.  Each person  nominated  for  election  has agreed to serve if
elected, and management has no reason to believe that any nominee will be unable
to serve.  If any nominee  for any reason is unable or  declines  to serve,  the
proxies will be voted for any substitute  nominee who shall be designated by the
present  Board of  Directors  to fill the  vacancy.  Stockholders  who desire to
nominate  persons for election to the Board must comply with the advance  notice
procedures specified in the Company's Bylaws.

         The  following  is  information   regarding  the  nominees,   including
information furnished by them as to their principal occupation for the preceding
five-year period, certain directorships and their ages as of March 17, 1997.

                                                                Director
         Name                               Age                  Since
         ----                               ---                  -----

         Samuel H. Armacost                 57                   1995
         Richard L. Casey                   50                   1987
         Myron Du Bain                      73                   1989
         Robert W. Schrier, M.D.            61                   1988
         Solomon H. Snyder, M.D.            58                   1992
         Burton E. Sobel, M.D.              59                   1996
         Eugene L. Step                     68                   1993

     Mr.  Armacost  was elected to the  Company's  Board of  Directors in August
1995. Mr. Armacost is a Principal of Weiss, Peck & Greer, L.L.C. Previously,  he
served as Managing  Director of Merrill Lynch Capital Markets and was President,
Director and Chief Executive Officer of BankAmerica Corporation. Mr. Armacost is
also a member of the Board of  Directors  of Chevron  Corporation,  The  Failure
Group, Inc. and SRI International.  In addition, Mr. Armacost is on the board of
the James Irvine Foundation and the Advisory Board of the California Academy of
Sciences, and he is a member of The Business Council.

         Mr.  Casey is  Chairman  of the Board,  President  and Chief  Executive
Officer  of Scios  Inc.  He joined  Scios in  December  1987 and has served as a
Director since that time. From early 1985 to 1987, he was with ALZA  Corporation
as Executive Vice President and President of ALZA Pharmaceuticals.  From 1976 to
1985 he worked for Syntex  Corporation,  in various positions including director
of marketing research,  director of sales, vice president and general manager of
Syntex Medical  Diagnostics.  Mr. Casey began his career in pharmaceuticals as a
sales  representative  for Eli Lilly and Company.  From 1968 to 1970,  Mr. Casey
served in the U.S.  Peace Corps in  Ethiopia.  Mr. Casey serves on the boards of
Guilford  Pharmaceuticals  Inc., an affiliated  publicly-held  development-stage
neuroscience   company   located  in  Baltimore,   Maryland;   VIVUS,   Inc.,  a
publicly-held  medical devices company  located in Menlo Park,  California;  and
Karo Bio AB, an affiliated privately-held Swedish biotechnology company.

         Mr.  Du Bain was  elected  a  Director  of Scios in June  1989.  He was
Chairman of the Board of Directors of SRI International  until his retirement in
1989.  Prior to that,  he was President  and Chief  Executive  Officer of Amfac,
Inc., a diversified  industry company,  Chairman,  President and Chief Executive
Officer of Fireman's  Fund  Corporation  and Vice  Chairman of American  Express
Company. He is a member of the board of directors of SRI International and Wells
Fargo Bank.


                                       2

<PAGE>

         Dr. Schrier was elected a Director of Scios in August 1988. He has been
Professor and Chairman, Department of Medicine, University of Colorado School of
Medicine,  since 1976. He has held numerous positions in professional societies,
including President of the National Kidney Foundation, President of the American
Society of Nephrology,  President of the Association of American Physicians, and
President of the  International  Society of Nephrology.  He received the Pasteur
Award  from the  University  of  Strasbourg;  the John  Phillips  Award from the
American  College of Physicians;  the David Hume Award from the National  Kidney
Foundation;   the  Mayo  Soley  Award  from  the  Western  Society  of  Clinical
Investigation;  and honorary  degrees from the University of Colorado and DePauw
University.  He has also served on the editorial boards of numerous professional
publications,  has authored over 600 scientific articles and has edited numerous
medical texts and reference  books.  He is a member of the Institute of Medicine
of the National Academy of Sciences.

     Dr. Snyder was elected a Director in September 1992. Dr. Snyder is Director
of the  Department  of  Neuroscience  and  Distinguished  Service  Professor  of
Neuroscience,  Pharmacology  and Molecular  Sciences and Psychiatry at The Johns
Hopkins  University,  and has been a member of the faculty there since 1966. Dr.
Snyder  received  the Albert  Lasker  Award for Basic  Biomedical  Research  and
Honorary  Doctor of Science  degrees from  Northwestern  University,  Georgetown
University  and Ben Gurion  University.  Dr. Snyder  received the Wolfe Award in
Medicine from the government of Israel for research  relating to receptors.  Dr.
Snyder is a member  of the  National  Academy  of  Sciences  and a Fellow of the
American Academy of Arts and Sciences. Dr. Snyder is also the author of numerous
articles and several  books.  Dr. Snyder is a founder and a director of Guilford
Pharmaceuticals Inc.

     Dr.  Sobel  was  elected  a  Director  in  February   1996.  Dr.  Sobel  is
Physician-in-Chief,  E.L.  Amidon  Professor  and  Chair  of the  Department  of
Medicine at The University of Vermont College of Medicine. Previously, Dr. Sobel
was Professor of Medicine at Barnes Hospital, Washington University and Director
of its Cardiovascular Division. Dr. Sobel has been a consultant to and served on
scientific   advisory  boards  of  several   pharmaceutical   and  biotechnology
companies.  Dr. Sobel has been the recipient of numerous  awards,  including the
American Heart Association's James B. Herrick Award and its Scientific Council's
Distinguished Achievement Award, as well as the American College of Cardiology's
Distinguished Scientist award. Dr. Sobel has been the editor of Circulation and,
since 1989, has served as editor of Coronary Artery Disease. His memberships and
fellowships  include  the  American  College  of  Physicians,  Royal  Society of
Medicine, American Heart Association and American College of Cardiology.

     Mr. Step was elected a Director  in February  1993.  From May 1956 until he
retired in December 1992,  Mr. Step was employed by Eli Lilly and Company,  most
recently as Executive Vice President,  President of the Pharmaceutical Division,
where  he was  responsible  for  U.S.  pharmaceutical  operations  and  for  the
operations  of Eli Lilly  International.  In  addition,  Mr.  Step served on Eli
Lilly's board of directors and executive committee. Mr. Step was chairman of the
board of directors of the Pharmaceutical Manufacturers Association and president
of the International Federation of Pharmaceutical Manufacturers Associations. He
is a member of the board of directors of Cell Genesys Inc., Guidant Corporation,
Medco Research Inc. and Pathogenesis Corporation.

                  INFORMATION ABOUT THE BOARD OF DIRECTORS AND
                             COMMITTEES OF THE BOARD

         Compensation of Directors -- Standard Arrangements

         Fees.  Directors who are not otherwise  employed by the Company receive
an annual  retainer of $12,000 and an additional fee of $1,000 for attendance at
each  meeting  of the  Board  of  Directors,  and $500  for  attendance  at each
committee  meeting  not  occurring  within 24 hours of a Board  meeting.  In the
fiscal year ended December 31, 1996, the aggregate compensation paid to eligible
non-employee Directors (8 individuals) under standard arrangements was $102,000.
This amount  includes  payments to William F. Miller and Donald E. O'Neill,  who
served as Directors of the Company  until May 1996.  Directors are also eligible
for  reimbursement  of expenses  incurred in connection with attendance at Board
meetings in accordance with Company policy.


                                       3
<PAGE>

         Stock Options.  Upon election to the Board, each non-employee  Director
is  automatically  granted an option to purchase  20,000 shares of Common Stock.
These options are currently  granted under the Company's  1992 Equity  Incentive
Plan (the "Equity  Plan"),  which contains  provisions  for automatic  grants to
non-employee Directors.  Prior to its expiration on June 30, 1994, option grants
to Directors were also made under the Company's 1989 Non-Employee Director Stock
Option Plan. These plans were approved by the Company's stockholders in May 1992
and May 1990,  respectively.  Only  non-employee  Directors  of the  Company are
eligible to receive options under the applicable  provisions of the Equity Plan,
and Mr.  Armacost,  Mr. Du Bain, Dr.  Schrier,  Dr. Sobel and Mr. Step have each
received option grants. Dr. Snyder voluntarily  declined to accept the grants to
which he was  entitled  upon his  elections  to the Board in  September  1992 in
connection with the merger of Nova Pharmaceutical  Corporation into the Company.
See "Proposal 2, Approval of Amendment of 1992 Equity  Incentive Plan - Terms of
Non-Employee Director Options".

     Board of Directors.  During fiscal 1996, there  were  five meetings of the
Board of Directors.

     Audit  Committee.  The  Audit  Committee  consists  of  three  non-employee
Directors: Mr. Step (Chairman),  Mr. Armacost and Dr. Sobel. The Audit Committee
met four times in fiscal 1996. Among the committee's  functions are recommending
engagement of the Company's independent  auditors,  approving services performed
by such auditors,  and reviewing and evaluating the Company's accounting systems
and its system of internal accounting controls.

     Compensation  Committee.  The  Compensation  Committee  consists  of  three
non-employee Directors:  Mr. Armacost (Chairman),  Mr. Du Bain and Mr. Step. Mr.
The committee met five times during fiscal 1996. Among the committee's functions
are establishing the Company's  compensation programs for all employees,  fixing
the compensation levels of executive officers of the Company,  and administering
and making awards under the Company's incentive programs.

         Nominating  Committee.  The  Nominating  Committee  consists  of  three
non-employee Directors: Mr. Du Bain (Chairman),  Dr. Schrier and Dr. Snyder. The
committee  met one time in fiscal  1996.  Among the  committee's  functions  are
recommending nominees to serve on the Board of Directors,  recommending size and
composition  of the Board based on studies  conducted by the  committee,  making
recommendations to the Board regarding  stockholders' comments as to composition
of the Board, making  recommendations  concerning membership of Board committees
and Board and committee  fees,  and  consulting  with the Board of Directors and
management to determine criteria for nominations.  The Nominating Committee will
consider  nominees  recommended  by  stockholders.   Any  such  recommendations,
together with the nominee's  qualifications and consent to being considered as a
nominee,  should be sent to the  Secretary of the Company no later than November
30, 1997 in order to be  considered  for election at the 1998 Annual  Meeting of
Stockholders.

         In fiscal 1996, all Directors  attended at least 75% of the meetings of
the Board and all committees of the Board of which they were members.


                                       4
<PAGE>

           SECURITY OWNERSHIP OF MANAGEMENT AND PRINCIPAL STOCKHOLDERS

                              Beneficial Ownership

         The  following  table  sets forth  certain  information  regarding  the
beneficial  ownership of the Company's Common Stock at March 17, 1997 by (i) all
persons  known by the  Company  to be  beneficial  owners of more than 5% of its
Common Stock, (ii) each Director,  (iii) each of the executive officers named in
the  Summary  Compensation  Table  included  herein and (iv) all  Directors  and
executive officers of the Company as a group.

<TABLE>
<CAPTION>

                                                  Beneficial Ownership(1)
                                               ------------------------------
                                               Beneficially      Approximate
Officers, Directors &                             Owned            Percent
5% Stockholders                                 Shares (2)         of Class
- ----------------------------------------------------------------------------
<S>                                            <C>               <C>

State of Wisconsin Investment Board            2,009,100 (3)       5.6%
P. O. Box 78432
Madison, WI 53707

Samuel H. Armacost                                17,000            *
Richard L. Casey                                 534,760 (4)       1.5%
Myron Du Bain                                     40,500 (4)        *
Robert W. Schrier, M.D.                           15,800            *
Solomon H. Snyder, M.D.                           10,000            *
Burton E. Sobel, M.D.                              5,000            *
Eugene L. Step                                    18,000            *

Elliott B. Grossbard, M.D.                       170,616            *
John A. Lewicki, Ph.D.                           172,567            *
John H. Newman                                   181,118 (4)        *
Armin H. Ramel, Ph.D.                             66,142            *

All officers and directors as a
  group (13 persons)                           1,274,668 (4)        3.5%

<FN>
- ----------

* less than 1%

(1)  Unless  otherwise  indicated below and subject to community  property laws,
     each  stockholder has sole voting and investment  power with respect to the
     shares beneficially owned.

(2)  For Mr. Armacost, Mr. Casey, Mr. Du Bain, Dr. Schrier, Dr. Sobel, Mr. Step,
     Dr. Grossbard,  Dr. Lewicki, Mr. Newman and Dr. Ramel, and all officers and
     directors as a group,  includes  7,000,  500,000;  20,500;  15,500;  5,000;
     17,000;   168,332;   156,666;   121,833;   64,554;  and  1,113,050  shares,
     respectively,  issuable upon exercise of  outstanding  options  exercisable
     within sixty days of March 17, 1997.

(3)  Information  is as of  December  31,  1996 as  provided  by the  holder  on
     Schedule 13G filed with the Securities and Exchange Commission.

(4)  With respect to Mr.  Casey,  includes  8,737 shares held in a trust for the
     benefit  of Mr.  Casey's  children,  of which  Mr.  Casey  and his wife are
     trustees.  With respect to Mr. Du Bain,  includes  10,000  shares held in a
     revocable  living trust for the benefit of Mr. Du Bain and his wife; Mr. Du
     Bain is a trustee of such trust. With respect to Mr. Newman, includes 7,000
     shares held in his  spouse's  IRA account and 2,000  shares held in a trust
     for the benefit of Mr. Newman's children,  of which Mr. Newman and his wife
     are trustees.
</FN>
</TABLE>

     The Company is not aware of any material  proceeding  to which any Director
or executive  officer of the Company or any  associate  of any such  Director or
executive  officer is a party adverse to the Company or any of its  subsidiaries
or has a material interest adverse to the Company or any of its subsidiaries.



                                       5
<PAGE>

Compliance with Section 16(a) of the Exchange Act

         Section 16(a) of the  Securities  Exchange Act of 1934, as amended (the
"Exchange  Act"),  requires  the  Company's  Directors,  executive  officers and
holders of more than ten  percent  (10%) of the  Company's  Common  Stock  ("10%
Holders")  to file with the  Securities  and  Exchange  Commission  (the  "SEC")
initial reports of ownership and reports of changes in ownership of Common Stock
and other equity securities of the Company.  Directors,  executive  officers and
10% Holders are required by SEC regulation to furnish the Company with copies of
all Section 16(a) forms they file.

         The Company  believes  that during the fiscal year ended  December  31,
1996,  its  Directors,  executive  officers  and 10% Holders  complied  with all
Section 16(a) filing  requirements.  In making this  statement,  the Company has
relied upon the written representations of its Directors, executive officers and
certain other reporting persons.

                             EXECUTIVE COMPENSATION

         The following  table discloses  compensation  received by the Company's
Chief  Executive  Officer  and each of its four  other most  highly  compensated
executive  officers at December 31, 1996 for the fiscal years ended December 31,
1996, 1995 and 1994.

<TABLE>
<CAPTION>
                           SUMMARY COMPENSATION TABLE
                                                                           Long-Term
                                                                           Compensation
                                      Annual Compensation                  Awards
                             -------------------------------------         ------------

                                                                           Securities
Name                                                                       Underlying           All Other
and                                                                        Stock                Compen-
Principal                                 Salary         Bonus (1)         Options              sation (2)
Position                      Year          ($)            ($)              (#)                  ($)
- --------                      ----        -------        -------           -------              ----
<S>                           <C>         <C>            <C>               <C>                  <C>

Richard L. Casey              1996        $400,000       $120,000          100,000              $3,000
  Chairman of the             1995        $400,000             --          120,000              $3,000
  Board, President            1994        $400,000       $104,000               --              $3,000
  and Chief Executive
  Officer

Elliott B. Grossbard, M.D.    1996        $218,500       $105,000 (3)        9,375              $3,000
  Vice President of           1995        $208,000        $60,577 (3)       39,000              $3,000
  Medical and                 1994        $208,000        $80,000 (3)           --              $3,000
  Regulatory Affairs

John A. Lewicki, Ph.D.        1996        $215,500        $40,000            6,250              $3,000
  Vice President              1995        $208,000        $24,904           39,000              $3,000
  of Research                 1994        $208,000        $40,000               --              $3,000

John H. Newman                1996        $185,500        $65,000            9,375              $3,000
  Vice President of           1995        $178,500        $24,425           39,000              $3,000
  Legal Affairs; General      1994        $178,500        $60,000               --              $3,000
   Counsel & Secretary

Armin H. Ramel, Ph.D.         1996        $202,000        $42,000            6,250              $3,000
  Vice President of           1995        $195,700        $20,084           37,000              $3,000
   Development                1994        $195,700        $35,000               --              $3,000

<FN>
- ---------------
(1)  Except as is further described in footnote 3 below, bonus amounts represent
     the value of awards under the Company's  Employee Incentive Plan. Awards to
     executive  officers  under  this  plan  are  determined   annually  by  the
     Compensation Committee.

(2)  Consists of Company matching  contributions under the 401(k) Profit Sharing
     Plan and Trust, which was established in 1986. As of December 31, 1996, the
     Company made matching  contributions of 100% of participant  contributions,
     up  to a  maximum  of  $3,000  per  participant  per  plan  year.  Employee
     contributions  are at all times 100% vested.  The  Company's  contributions
     vest based on years of service:  0% for less than one year; 25% for one but
     less than two years;  50% for two but less than three  years;  and 100% for
     three or more years. Federal tax laws impose an overall limit on the amount
     that may be contributed by participants each year under 401(k) plans.

(3)  Dr. Grossbard's bonuses for 1996, 1995 and 1994 include forgiveness of
     $30,000, $25,000 and $25,000,  respectively, in each year under a loan made
     to him at the time he joined the Company.

</FN>
</TABLE>

                                       6
<PAGE>


                       STOCK OPTION GRANTS AND EXERCISES

      In the  Company's  efforts  to  recruit  the best  available  talent  in a
competitive  labor market,  the Company  grants stock options to provide  equity
incentives. The Company has granted stock options under the 1983 Incentive Stock
Option Plan (expired by its terms on March 5, 1993), the 1986 Supplemental Stock
Option Plan  (expired by its terms on January 16, 1996),  the 1989  Non-Employee
Director  Stock Option Plan (expired by its terms on June 30, 1994),  the Equity
Plan and the 1996 Non-Officer Stock Option Plan.

      The  following  table  provides  information  on stock options held by the
executive  officers  named  in  the  Summary   Compensation   Table,   including
information  as to grants and exercises  for the fiscal year ended  December 31,
1996.


<TABLE>
<CAPTION>

                        Option Grants in Last Fiscal Year

                                                                              Potential Realizable Value at
                                                                              Assumed Annual Rates of Stock
                                  Individual Grants                           Price Appreciation for Option Term
- ---------------------------------------------------------------------------   ----------------------------------
                  No. of           % of
                  Securities       Total
                  Under-           Options
                  lying            Granted to       Exercise
                  Options          Employees        or Base      Expira-
                  Granted (1)      in Fiscal        Price        tion
Name                (#)            Year             ($/Sh)       Date          0%($)        5%($)          10%($)
- ----              --------         ---------        --------     --------      -----        -----          ------
<S>               <C>              <C>              <C>          <C>           <C>          <C>            <C>

R. Casey          36,000            5.93%           $4.56        01/11/06       0           $103,260       $261,661
                  64,000           10.54%           $5.44        02/04/06       0           $218,780       $554,387

E. Grossbard       9,375            1.54%           $5.44        02/04/06       0           $ 32,048       $ 81,208

J. Lewicki         6,250            1.03%           $5.44        02/04/06       0           $ 21,365       $ 54,139

J. Newman          9,375            1.54%           $5.44        02/04/06       0           $ 32,048       $ 81,208

A. Ramel           6,250            1.03%           $5.44        02/04/06       0           $ 21,365       $ 54,139

<FN>
- ---------

(1)  These options vest in equal monthly  installments  commencing on January 1,
     2000 and ending on December 31, 2000. See  "Compensation  Committee Report"
     for additional  information  on these stock  options.  Mr. Casey's grant of
     36,000 shares was made under the 1986 Supplemental Stock Option Plan (which
     plan expired  January 16,  1996);  all other grants in this table were made
     pursuant to the 1992 Equity Incentive Plan.
</FN>
</TABLE>


                 Aggregated Option Exercises in Last Fiscal Year
                            and FY-End Option Values
<TABLE>
<CAPTION>
                                                 Number of Securities Underlying              Value of Unexercised,
                      Shares                     Unexercised Options at FY-End             In-the-Money Options at FY-End
                   Acquired on       Value       -------------------------------      -----------------------------------------
Name               Exercise (#)   Realized ($)   Exercisable (#)   Unexercisable (#)  Exercisable (1)($)   Unexercisable (1)($)
- ----               ------------   ------------   ---------------   -----------------  ------------------   --------------------
<S>                <C>            <C>            <C>               <C>                <C>                  <C>

R. Casey                0             0          480,000           280,000                  0              $101,812

E. Grossbard            0             0          160,000            68,375                  0                $6,592

J. Lewicki              0             0          156,000            65,250                  0                $4,395

J. Newman               0             0          124,500            60,375                  0                $6,592

A. Ramel                0             0           56,944            61,306            $889.75                $4,677

<FN>
- ----------
(1)      Based on the fair market value of the  Company's  Common Stock at
         December 31, 1996 ($6.14) minus the exercise price of the options.

</FN>
</TABLE>

                                       7
<PAGE>

                         COMPENSATION COMMITTEE REPORT (1)

         The Compensation  Committee of the Board of Directors (the "Committee")
is responsible  for  establishing  the Company's  compensation  programs for all
employees, including executives. For executive officers, the Committee evaluates
performance  and  determines  compensation  policies  and levels.  In 1996,  the
Committee was composed of Mr.  Armacost,  Mr. Du Bain and Mr. Step, none of whom
were officers or employees of the Company.

Compensation Philosophy

         The goals of the compensation  program are to align  compensation  with
business  objectives  and  performance,  and to enable the  Company to  attract,
retain and reward  executive  officers and other key employees who contribute to
the long-term  success of the Company and to motivate them to enhance  long-term
stockholder value. Key elements of this philosophy are:

   -     The Company pays  competitively with leading  biotechnology  companies
         with which the  Company  competes  for  talent.  To ensure  that pay is
         competitive,  the Company  regularly  compares its pay  practices  with
         these companies and sets its pay parameters based on this review.

   -     The Company  maintains  annual incentive  opportunities  sufficient to
         provide  motivation to achieve specific operating goals and to generate
         rewards that bring total compensation to competitive levels.

   -     The  Company   provides   significant   equity-based   incentives  for
         executives  and other key  employees to ensure that they are  motivated
         over the long term to respond to the Company's business  challenges and
         opportunities as owners and not just as employees.

         The primary  components  of  executive  compensation  are base  salary,
annual incentives and long-term equity incentives. Over the last four years, the
Committee  has not granted a salary  increase to the CEO and has granted  modest
salary  increases  over the last two years to other  executives.  These  actions
reflect  the  Committee's  intent  to lower  the  relative  percentage  of fixed
compensation (base salary) and increase the relative  percentage of variable pay
or pay based on performance (annual and long-term equity incentives).

         The  Committee's  objective  in  general  is to set each  component  of
executive compensation at the market average when compared to a group of leading
companies in the  biotechnology  industry of comparable  size who compete in the
job  market  for  individuals  with  the  skills  desired  by the  Company  (the
"comparator  group").  The companies  chosen for the  comparator  group used for
compensation  purposes  include  several of the  companies  which  comprise  the
published  industry  index  in the  Performance  Graph  included  in this  Proxy
Statement.  Because  the  Committee  believes  that the  Company's  most  direct
competitors for executive talent are not necessarily all of the companies in the
broad industry index,  many smaller or earlier stage  companies  included in the
index are not included in the comparator group.

- --------
     1   Notwithstanding  anything  to  the  contrary  set  forth  in any of the
         Company's  previous  filings  under  the  Securities  Act of  1933,  as
         amended, or the Exchange Act that might incorporate by reference future
         filings in whole or in part,  including this Proxy  Statement,  neither
         this Report nor the Performance  Graph in this Proxy Statement shall be
         incorporated by reference into any such filings.

                                       8
<PAGE>

         Base Salary.  The Committee  annually reviews each executive  officer's
base salary  against the base salaries  paid for similar  positions by companies
within the  comparator  group.  A range of salary levels is  established by this
comparison  centered on the 50th percentile  salary in the comparator  group for
comparable positions.  Within this range, the Committee  subjectively  considers
individual factors,  including individual performance,  level of responsibility,
prior experience, breadth of knowledge and competitive pay practices, as well as
the extent to which the Company achieved its corporate  objectives  described in
the section below  entitled  Annual  Incentive.  From year to year, the relative
weighting of the individual  components and the corporate  performance component
may differ from  officer to officer,  and can be expected to change over time in
response  to  the  Company's   development   stage  and  the  evolution  of  the
biotechnology  industry.  Actual base  salaries  in 1996  remained at the median
level for the comparator group.

         Annual  Incentive.  The Employee  Incentive  Plan, an annual  incentive
award plan, is the variable pay program for officers and other  employees of the
Company to earn  additional  annual  compensation.  The actual  incentive  award
earned  depends  on the  extent  to which  Company  and  individual  performance
objectives  are achieved.  At the start of each year, the Committee and the full
Board of Directors review and approve the annual performance  objectives for the
Company and individual  officers.  The Company  objectives consist of operating,
strategic  and  financial  goals  that  are  considered  to be  critical  to the
Company's  fundamental  long-term goal -- building stockholder value. For fiscal
1996, these objectives, listed in order of relative importance, were:

- -    completing the key development benchmarks for the Company's lead products -
     AURICULIN(R)  anaritide,  NATRECOR(R) hBNP and FIBLAST(R)  trafermin -
     that had been identified for accomplishment in 1996

- -    securing commercial partners for certain of the Company's technologies and
     commercial operations

- -    financial  performance  related to the Company's cash utilization  and
     expanding the sales and profits derived from the  Company's  commercial
     operations  group, which markets certain products to psychiatrists and
     mental health clinics

- -    understanding, identifying and developing additional products from the
     Company's research pipeline as candidates for clinical testing

         After the end of the year, the Committee  evaluates the degree to which
the Company has met its  objectives  and, at the  discretion  of the  Committee,
establishes  a total  incentive  award pool under the Employee  Incentive  Plan.
Individual awards are determined by evaluating the Company's overall performance
and by evaluating  each  participant's  performance  against  objectives for the
year. The incentive award pool is then allocated based on the assessment of each
participant's   contribution   to   achievement   of  corporate  and  individual
objectives.  Awards are paid in cash and  distributions are made in the February
following the performance year.

         In February,  the Committee determined that the Company had achieved or
exceeded  almost all of its key  corporate  objectives  for fiscal 1996 that are
outlined  above.  The Committee  concluded that the following  goals were met or
exceeded: patient enrollment targets in both the AURICULIN and NATRECOR clinical
programs;  advancing NATRECOR into Phase III trials; manufacture of the required
qualification lots for both these products;  extensive  preparations for the NDA
filings and  inspections  that would follow  successful  completion  of clinical
programs;  assistance to Kaken  Pharmaceutical  Co., Ltd., the Company's FIBLAST
licensee in Japan, in filing an NDA in Japan for wound healing; establishment of
a major  collaboration  on FIBLAST with American Home Products  Corporation  for
stroke and vascular  disease;  initiation and completion of the initial Phase II
safety study of FIBLAST in stroke and  initiation of clinical  investigation  of
FIBLAST in peripheral vascular disease;  securing for the commercial  operations
division an additional product (EFFEXOR(R) venlaflaxine HCl) to co-promote;  and
financial objectives,  including the contribution from the commercial operations
division and bettering cash utilization  targets.  The Committee determined that
the Company had been only  partially  successful  in achieving the 1996 goals of
the  research  division.  Based  on the  Company's  performance,  the  Committee
determined  that the  total  incentive  pool for  participants  in the  Employee
Incentive  Plan  would  be  85% of  the  maximum  possible  pool.  Based  on its
assessment of individual contribution to achievement of corporate and individual
objectives,  the Committee then  determined the 1996 incentive award for each of
the seven executives on the Company's corporate management committee.


                                       9
<PAGE>

         Long-Term  Incentives.  The Company's  long-term  incentive program for
officers  consists of the 1983  Incentive  Stock Option Plan,  (expired March 5,
1993),  the 1986  Supplemental  Stock Option Plan (expired January 16, 1996) and
the 1992 Equity  Incentive  Plan. The option program  utilizes  vesting  periods
(generally  four to five years) to  encourage  key  employees to continue in the
employ of the Company.  Through option grants,  executives  receive  significant
equity incentives to build long-term stockholder value. Grants have been made at
or above  100% of fair  market  value on the date of grant.  Executives  receive
value from these grants only if the Company's Common Stock  appreciates over the
long  term.  The size of  option  grants  is  determined  based  on  competitive
practices at companies in the comparator  group and the Company's  philosophy of
significantly  linking  executive  compensation with stockholder  interests.  In
addition,  the Committee  considers  the terms and number of options  previously
awarded in determining the size of option grants.

         In 1992,  the  Committee  granted  stock  options  that  vested  over a
five-year  period ending  December 31, 1997 to  executives  then employed by the
Company. Executives who received grants in 1992 did not receive additional stock
option  grants until 1995. In 1995 and 1996,  the Committee  reviewed the equity
incentives  of  executive  officers and made  additional  grants in each year to
remain competitive with the comparator group and maintain appropriate  long-term
incentives for key individuals. These grants will vest during 1997 through 2000.
The Committee  believes the approach of making grants that vest over an extended
time period creates an appropriate  focus on longer term objectives and promotes
executive retention.

         Section  162(m) of the Internal  Revenue Code limits the federal income
tax  deductibility of compensation  paid to the Company's CEO and to each of the
other four most highly compensated executive officers.  The Company intends that
the long-term incentive compensation paid to these executives will be deductible
by the Company under Section 162(m). The proposed  amendments to the 1992 Equity
Incentive Plan are intended to meet the  requirements of Section 162(m).  If the
proposed  amendment  to  the  Equity  Plan  is not  approved,  then  there  is a
possibility that certain  compensation will not be deductible by the Company for
tax purposes. See "Proposal No.2, Approval of Amendment of 1992 Equity Incentive
Plan."

Chief Executive Officer Compensation

         In the fall of 1992,  the  Committee  retained  Hewitt  Associates  (an
international  employee  compensation and benefits consulting firm) to conduct a
comprehensive  review of the base  salaries and  incentive  compensation  of all
continuing executive officers as compared to the comparator group. Following the
Hewitt Associates  review, the Committee set Mr. Casey's 1993 base annual salary
at $400,000.  This amount,  in addition to the annual incentive  provided by the
Employee  Incentive  Plan, was estimated to provide an annual cash  compensation
level at the  average of the  comparator  group.  In setting  this  amount,  the
Committee  took into account (i) its belief that Mr. Casey is one of the CEOs of
leading biotechnology  companies with significant and broad-based  experience in
the  pharmaceutical  industry,  (ii) the  scope of Mr.  Casey's  responsibility,
especially following the merger with Nova Pharmaceutical Corporation,  and (iii)
the Board's confidence in Mr. Casey to lead the Company's continued development.

         For 1994 through 1997,  the Committee  elected to maintain Mr.  Casey's
base salary at $400,000,  the same level as 1993. In doing so, the Committee has
intended to increase the relative portion of Mr. Casey's total compensation that
is variable  pay,  which is based on  achievement  of the  corporate  objectives
annually established by the Board and on increases in the Company's stock price.
See "Compensation Philosophy-Annual Incentive" above.


                                       10
<PAGE>

         In 1996,  the  Committee  determined  that Mr. Casey should  receive an
award of $120,000  (30% of his Base Salary)  under the Employee  Incentive  Plan
based on the Company's 1996 achievements against objectives and Mr. Casey's role
in producing the 1996 results.  In February 1996, the Committee  determined that
it would enhance Mr. Casey's  incentive to build long-term  stockholder value by
granting Mr. Casey an option to purchase  100,000 shares of stock that will vest
in the year 2000. At the time of this grant,  the Committee  determined  that it
would not make an additional grant to Mr. Casey during 1997.

Conclusion

         In summary, the Compensation Committee believes that, through the plans
and actions described above, a significant portion of the Company's compensation
program and, in particular,  Mr. Casey's  compensation are contingent on Company
performance,  and that  realization of benefits is closely linked to achievement
of key corporate objectives that will produce increases in long-term stockholder
value. The Company remains  committed to this philosophy of pay for performance,
recognizing  that  the  competitive  market  for  talented  executives  and  the
volatility of the Company's business may result in highly variable  compensation
for  a  particular  time  period.  We  will  continue  to  monitor  closely  the
effectiveness and  appropriateness  of each of the components of compensation to
reflect changes in the Company's business environment.

                                  COMPENSATION COMMITTEE
                                  Samuel H. Armacost, Chairman
                                  Myron Du Bain
                                  Eugene L. Step


           COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION

         In 1996, Scios paid $33,932 in portfolio management fees to Weiss, Peck
& Greer,  L.L.P., an investment firm of which Mr. Armacost is a principal.  Such
fees were paid in the normal course of business.


                                       11
<PAGE>
                                PERFORMANCE GRAPH

         The rules of the  Securities and Exchange  Commission  require that the
Company  include in this Proxy  Statement a  line-graph  presentation  comparing
five-year  stockholder  returns on an indexed basis with the Nasdaq Stock Market
(U.S.) and either a nationally recognized industry standard index or an index of
peer  companies  selected  by the  Company.  The  Company has elected to use the
Nasdaq  Pharmaceutical  Stocks Index for purpose of the  performance  comparison
that appears  below.  The graph assumes the  investment of $100 in the Company's
Common  Stock,  the Nasdaq  Stock  Market  (U.S.) and the Nasdaq  Pharmaceutical
Stocks  Index on December  31, 1991.  The stock price  performance  shown on the
graph below is not necessarily indicative of future price performance.

                 Comparison of Five Year Cumulative Total Return
                Among Scios Inc., Nasdaq Stock Market (U.S.) and
                       Nasdaq Pharmaceutical Stocks Index

EDGAR representation of data points used in printed graphic

<TABLE>
<CAPTION>
                           Scios        Nasdaq Stock Market    Nasdaq Pharm
                           -----        -------------------    ------------
            <S>            <C>          <C>                    <C>

            12/31/91       100.000           100.000             100.000
             1/31/92        92.222           105.847             104.360
             2/28/92        75.556           108.246              95.319
             3/31/92        66.111           103.137              86.573
             4/30/92        54.444            98.714              72.476
             5/29/92        62.222            99.996              75.173
             6/30/92        46.111            96.086              72.620
             7/31/92        45.000            99.490              76.552
             8/31/92        39.444            96.449              69.683
             9/30/92        36.111           100.034              68.385
            10/30/92        35.000           103.974              72.872
            11/30/92        48.333           112.247              84.050
            12/31/92        41.111           116.378              83.217
             1/29/93        33.889           119.691              77.348
             2/26/93        30.000           115.226              59.368
             3/31/93        31.111           118.561              59.903
             4/30/93        26.667           113.501              60.532
             5/28/93        26.667           120.281              63.012
             6/30/93        25.000           120.837              63.128
             7/30/93        25.556           120.980              61.317
             8/31/93        30.000           127.233              64.584
             9/30/93        33.333           131.022              68.440
            10/29/93        48.889           133.967              74.492
            11/30/93        46.111           129.972              72.857
            12/31/93        45.556           133.595              74.173
             1/31/94        41.667           137.650              76.428
             2/28/94        38.333           136.363              69.548
             3/31/94        32.778           127.976              60.497
             4/29/94        35.000           126.315              58.063
             5/31/94        29.722           126.624              57.279
             6/30/94        28.333           121.993              52.805
             7/29/94        28.333           124.495              54.403
             8/31/94        33.889           132.432              60.306
             9/30/94        30.000           132.094              59.474
            10/31/94        30.000           134.689              57.442
            11/30/94        26.667           130.221              57.695
            12/30/94        29.444           130.587              55.825
             1/31/95        34.444           131.318              58.916
             2/28/95        36.667           138.263              61.141
             3/31/95        33.889           142.360              60.267
             4/28/95        30.000           146.842              61.960
             5/31/95        15.833           150.628              62.741
             6/30/95        18.056           162.835              70.092
             7/31/95        18.889           174.804              76.127
             8/31/95        18.333           178.347              85.131
             9/29/95        18.333           182.448              87.581
            10/31/95        16.111           181.403              84.307
            11/30/95        17.222           185.662              88.537
            12/29/95        19.167           184.674             102.133
             1/31/96        23.889           185.587             111.004
             2/29/96        21.944           192.660             108.912
             3/29/96        20.278           193.300             106.282
             4/30/96        21.111           209.334             111.773
             5/31/96        32.500           218.945             115.557
             6/28/96        29.444           209.078             103.273
             7/31/96        25.000           190.458              92.030
             8/30/96        25.556           201.130              98.696
             9/30/96        27.500           216.524             105.600
            10/31/96        25.556           214.151             100.854
            11/29/96        25.556           227.423              99.361
            12/31/96        27.292           227.164             102.243

</TABLE>

                                       12

<PAGE>
                     CERTAIN RELATIONSHIPS AND TRANSACTIONS

     In 1993, the Company formed Guilford Pharmaceuticals Inc. ("Guilford"). Mr.
Casey and Dr.  Snyder are  directors of  Guilford.  The Company  currently  owns
approximately 10% of the outstanding stock of Guilford. In 1996, Guilford rented
space from the Company, for which it paid $228,323.

         In November  1991,  the Company made a commitment to loan up to $80,000
to Dr. Elliott B.  Grossbard in connection  with his joining the Company as Vice
President of Medical and Regulatory  Affairs.  The commitment was made to permit
Dr.  Grossbard to purchase a  residence.  In June 1993,  the Company  loaned Dr.
Grossbard $80,000, which loan bore interest at the annual rate of 3.72%. On each
of May 31, 1994, 1995 and 1996, $25,000,  $25,000 and $30,000  respectively,  of
principal and all interest were forgiven.

                                   PROPOSAL 2
               APPROVAL OF AMENDMENT OF 1992 EQUITY INCENTIVE PLAN

         In February 1992, the Board of Directors adopted,  and the stockholders
subsequently  approved,  the Company's  1992 Equity  Incentive Plan (the "Equity
Plan").  There were originally  2,500,000  shares of the Company's  Common Stock
authorized  for  issuance  under the  Equity  Plan.  In May  1992,  the Board of
Directors  amended the Equity Plan and increased  the number of shares  reserved
thereunder to 3,500,000 shares. Stockholders approved this increase in September
1992.  Since that time,  the Company has not sought an increase in the number of
shares  reserved  under the Equity Plan. In February 1997, the Board reserved an
additional  1,500,000  shares for issuance  under the Equity Plan,  extended the
term of the Equity  Plan to  February  2, 2007 and  adopted a 300,000  share per
person per  calendar  year limit  pursuant  to  Section  162(m) of the  Internal
Revenue Code of 1986, as amended (the "Code").

         At March  17,  1997,  options  (net of  canceled  or  expired  options)
covering an aggregate of 2,721,724 shares of the Company's Common Stock had been
granted under the Equity Plan. At that date,  203,674 shares remained  available
for future grant out of the of the original  3,500,000  shares  authorized under
the Equity Plan in 1992. During the last fiscal year, under the Equity Plan, the
Company  has  granted to all current  executive  officers as a group  options to
purchase  201,500  shares  at  exercise  prices  of  $5.44 to  $6.88  per  share
(including  the  95,250  shares  granted  under  the  Equity  Plan to the  named
executive  officers  listed in the table  entitled  Option Grants in Last Fiscal
Year), to all employees as a group  (excluding  executive  officers)  options to
purchase  350,409 shares at exercise prices of $5.44 to $6.13 per share,  and to
one eligible  non-employee  Director an option to purchase  20,000  shares at an
exercise price of $5.85 per share.

         The Board  amended  the Equity  Plan to  increase  the number of shares
available  in order to ensure  that the  Company  can  continue  to grant  stock
options  to  employees  at  levels  determined  appropriate  by the  Board,  and
anticipates that this increase will be an adequate reserve for at least the next
several years.

         Section  162(m) of the Code  denies a  deduction  to any  publicly-held
corporation for certain  compensation  paid to specified  employees in a taxable
year to the extent  that the  compensation  exceeds  $1,000,000  for any covered
employee.  See "Federal  Income Tax  Information"  below for a discussion of the
application of Section 162(m). In light of the Section 162(m) requirements,  the
Equity Plan was amended to provide that no individual may be granted  options to
purchase  more than  300,000  shares of Common Stock during any one fiscal year.
Previously  no such  formal  limitation  was  placed  on the  number  of  shares
available for option grants to an individual during a fiscal year.

         Stockholders  are requested in this Proposal to approve the  additional
1,500,000  shares  reserved  under the Equity Plan,  the extension of the Equity
Plan's term and the adoption of the Section 162(m) limit.  The affirmative  vote
of the holders of a majority of the shares  present in person or  represented by
proxy and  entitled  to vote at the  meeting  will be  required  to approve  the
amendment of the Equity Plan.

                        THE BOARD OF DIRECTORS RECOMMENDS
                         A VOTE IN FAVOR OF PROPOSAL 2.

                                       13
<PAGE>

         The essential features of the Equity Plan are outlined below:

GENERAL

         The Equity Plan  provides for the grant or issuance of incentive  stock
options,  nonstatutory stock options, restricted stock purchase awards and stock
bonuses to employees, directors and consultants. Incentive stock options granted
under the Equity  Plan are  intended  to qualify as  "incentive  stock  options"
within the meaning of Section 422 of the Code.  Nonstatutory  (or  supplemental)
stock  options  granted  under the Equity  Plan are  intended  not to qualify as
incentive stock options under the Code. See "Federal Income Tax Information" for
a discussion of the tax treatment of the various  awards  included in the Equity
Plan.

PURPOSE

         The Equity Plan provides a means by which selected employees, directors
and consultants to the Company, and its affiliates,  may be given an opportunity
to purchase  Common  Stock of the Company.  The Company,  by means of the Equity
Plan,  seeks to retain the services of persons who are now employees,  directors
or  consultants  to the  Company  or its  affiliates,  to secure  and retain the
services of new employees,  directors and consultants, and to provide incentives
for such persons to exert maximum efforts for the success of the Company and its
affiliates.

FORMS OF BENEFIT

         The Equity Plan  provides for  incentive  stock  options,  nonstatutory
stock options,  restricted stock purchase awards and stock bonuses (collectively
"Stock Awards").

ADMINISTRATION

         The Equity Plan is administered by the Board unless and until the Board
delegates  administration  to a  committee  composed  of two (2) or  more  Board
members, all of the members of which committee may be non-employee directors (as
defined under the Exchange Act) and may also be, in the discretion of the Board,
outside directors (as defined under the Code). If administration is delegated to
a committee,  such committee will have, in connection with the administration of
the Equity Plan, the powers possessed by the Board,  subject,  however,  to such
resolutions,  not inconsistent with the provisions of the Equity Plan, as may be
adopted from time to time by the Board.  The Board or the committee may delegate
to a  subcommittee  of one or more  members of the Board the  authority to grant
Stock  Awards to eligible  persons who are not then subject to Section 16 of the
Exchange  Act and/or who are  either (i) not then  employees  covered by Section
162(m) of the Code and are not  expected to be covered by Section  162(m) of the
Code at the time of  recognition of income  resulting from such Stock Award,  or
(ii)  not  persons  with  respect  to whom  the  Company  wishes  to  avoid  the
application  of Section 162(m) of the Code. The Board may abolish a committee or
subcommittee  at any time and  revest  in the Board  the  administration  of the
Equity Plan.  The Board has delegated the  administration  of the Equity Plan to
the Compensation  Committee,  each member of whom satisfied the requirements set
forth above.  References  to the Board  include any  committee  or  subcommittee
designated by the Board.

         The  Board has the power to  determine  from time to time  which of the
persons  eligible  under the Equity  Plan shall be granted  awards,  the type of
awards to be granted,  when and how each award shall be granted, to construe and
interpret the Equity Plan and awards  granted under it, and to establish,  amend
and revoke rules and regulations  for its  administration.  Notwithstanding  the
foregoing,   options   granted  to   non-employee   directors   of  the  Company
("Non-Employee  Directors  Options")  will be  governed  solely  as set forth in
"Terms of Non-Employee Director Options" below. The Board may correct any defect
in the  Equity  Plan or in any award  agreement  to make the  Equity  Plan fully
effective.


                                       14
<PAGE>

SHARES SUBJECT TO THE PLAN

         The Common  Stock that may be sold  pursuant to awards under the Equity
Plan shall not exceed in the aggregate  5,000,000 shares of the Company's Common
Stock,  including the additional 1,500,000 shares for which stockholder approval
is being  sought.  If any  award  expires  or  terminates,  in whole or in part,
without having been exercised in full, the stock not purchased  under such award
will revert to and again become  available  for issuance  under the Equity Plan.
The Common Stock subject to the Equity Plan may be unissued shares or reacquired
shares, bought on the market or otherwise.

ELIGIBILITY

         Incentive stock options may be granted only to employees.  Nonstatutory
stock options, restricted stock purchase awards and stock bonuses may be granted
only to employees, directors or consultants.

         No person is eligible for the grant of an incentive stock option if, at
the time of grant, such person owns stock possessing more than ten percent (10%)
of the total combined voting power of all classes of stock of the Company unless
the exercise  price of such option is at least one hundred ten percent (110%) of
the fair market value of such Common Stock  subject to the option at the date of
grant and the option is not  exercisable  after the expiration of five (5) years
from the date of grant, or in the case of a restricted stock purchase award, the
purchase  price is at least one hundred  percent (100%) of the fair market value
of  Common  Stock  subject  to the award at date of  grant.  No person  shall be
eligible to be granted Stock Awards  covering  more than three hundred  thousand
(300,000) shares of the Company's Common Stock in any calendar year.

TERMS OF STOCK AWARDS UNDER THE PLAN

         The following are the terms of Stock Awards under the Equity Plan other
than  options  granted to  non-employee  directors.  See "Terms of  Non-Employee
Director Options" below.

         Term and  Termination. No option  is exercisable  after the expiration
of ten (10) years from the date it was granted.

         In the event an optionee's  continuous status as an employee,  director
or consultant is terminated, the optionee may exercise his or her option (to the
extent that the optionee was entitled to exercise it at the time of termination)
but only  within  the  earlier  of (i) the  date  three  (3)  months  after  the
termination  of the  optionee's  continuous  status as an employee,  director or
consultant, or (ii) the expiration of the term of the option as set forth in the
option agreement.

         An optionee's option agreement may also provide that if the exercise of
the option following the termination of the optionee's  continuous  status as an
employee,  director, or consultant would result in liability under Section 16(b)
of the Exchange Act,  then the option shall  terminate on the earlier of (i) the
expiration of the term of the option set forth in the option agreement,  or (ii)
the tenth (10th) day after the last date on which such exercise  would result in
such liability under Section 16(b) of the Exchange Act.  Finally,  an optionee's
option  agreement may also provide that if the exercise of the option  following
the termination of the optionee's continuous status as an employee,  director or
consultant would be prohibited at any time solely because the issuance of shares
would violate the registration requirements under the Securities Act of 1933, as
amended, then the option shall terminate on the earlier of (i) the expiration of
the term of the option as set forth in the immediately  preceding paragraph,  or
(ii) the expiration of a period of three (3) months after the termination of the
optionee's continuous status as an employee, director or consultant during which
the  exercise  of the  option  would not be in  violation  of such  registration
requirements.


                                       15
<PAGE>

         In the event an optionee's  continuous status as an employee,  director
or consultant terminates as a result of the optionee's death or disability,  the
optionee (or such optionee's estate, heirs or beneficiaries) may exercise his or
her option,  but only within the period ending on the earlier of (i) twelve (12)
months  following  such  termination  in the case of  disability,  eighteen (18)
months in the case of death (or such longer or shorter  period as  specified  in
the option  agreement)  or (ii) the  expiration of the term of the option as set
forth in the option agreement.

         In the event a stock bonus or restricted stock  recipient's  continuous
status as an  employee,  director  or  consultant  terminates,  the  Company may
repurchase or otherwise reacquire any or all of the shares of stock held by that
person  which have not vested as of the date of  termination  under the terms of
the stock bonus or restricted stock purchase  agreement  between the Company and
such person.

         Exercise/Purchase  Price.  The exercise price of each  incentive  stock
option will not be less than one hundred percent (100%) of the fair market value
of the Company's  Common Stock on the date of grant.  The exercise price of each
nonstatutory stock option will not be less than eighty-five percent (85%) of the
fair market value on the date of grant.  The purchase price of restricted  stock
will not be less than eighty-five  percent (85%) of the fair market value of the
Company's  Common  Stock on the date such award is made.  Stock  bonuses  may be
awarded in consideration  for past services  actually rendered to the Company or
for its benefit.

         Consideration. The purchase price of stock acquired pursuant to a Stock
Award  is paid  either  in cash at the  time of  exercise  or  purchase,  or (if
determined by the Board at the time of grant for an option) by deferred  payment
or other  arrangement  or in any other form of legal  consideration  that may be
acceptable  to the  Board.  Additionally,  in the case of an option  (and in the
discretion of the Board at the time of the grant of an option), by delivering to
the Company  previously  acquired shares of Common Stock of the Company.  In the
case of any  deferred  payment  arrangement,  interest  will be payable at least
annually and will be charged at the minimum rate of interest  necessary to avoid
the treatment as interest of amounts that are not stated to be interest.

         Regulation  T. In  connection  with the  exercise of options  under the
Equity Plan, the Company's  regular  procedures may qualify for certain programs
authorized  by  Regulation  T  promulgated  by the  Federal  Reserve  Board.  If
optionees  elect to use such  program,  the  Company  intends to comply with the
requirements of Regulation T.

         Transferability.  An incentive  stock option shall not be  transferable
except  by will  or by the  laws of  descent  and  distribution,  and  shall  be
exercisable during the lifetime of the person to whom the incentive stock option
is granted only by such person.  A stock bonus or  restricted  stock award shall
not be transferable except by will or by the laws of descent and distribution or
pursuant to a domestic  relations  order. A  nonstatutory  stock option shall be
transferable  only  to the  extent  specifically  provided  for  in  the  option
agreement  evidencing  the  nonstatutory  stock  option,  provided  that  if the
nonstatutory stock option agreement does not provide for  transferability,  then
the  option is not  transferable  except by will or by the laws of  descent  and
distribution  or pursuant to a domestic  relations  order.  An award  holder may
designate a beneficiary who may exercise his or her award after death.

         Vesting.  The total number of shares of stock subject to an option may,
but need not, be allotted in periodic  installments.  The option  agreement  may
provide  that from time to time during  each of such  installment  periods,  the
option may become exercisable ("vest") with respect to some or all of the shares
allotted to that period, and may be exercised with respect to some or all of the
shares  allotted to such period  and/or any prior  period as to which the option
became vested but was not fully exercised. The option agreement may also provide
that an optionee may exercise an option prior to full vesting, provided that the
Company may have a repurchase right with respect to any unvested shares.


                                       16
<PAGE>

         Restricted  stock purchase  awards and stock bonuses  granted under the
Equity  Plan may be  granted  pursuant  to a  repurchase  option in favor of the
Company in accordance with a vesting schedule determined by the Board.

         Re-Load Options.  The Board has the authority to include as part of any
option a  provision  entitling  the  optionee  to a further  option (a  "Re-Load
Option") in the event the optionee exercises the original option by surrendering
other shares of Common Stock to the Company.  Any such Re-Load  Option (i) shall
be for a number of shares equal to the number of shares surrendered;  (ii) shall
have an expiration date which is the same as the expiration date of the original
option; and (iii) shall have an exercise price equal to the fair market value of
the Common  Stock on the date of exercise of the  original  option  (110% in the
case of certain 10%  stockholders  if the Re-Load  Option is an incentive  stock
option).  No Re-Load Options have been granted,  and it is not anticipated  that
any Re-Load Options will be granted in the near future.

TERMS OF NON-EMPLOYEE DIRECTOR OPTIONS

         Non-employee  directors are only eligible for the grant of nonstatutory
stock options under the Equity Plan.  The granting and terms of such options are
subject  to the  following  special  provisions  of the Equity  Plan.  Except as
described  below,   Non-Employee  Director  Options  are  subject  to  the  same
provisions of the Equity Plan applicable to other nonstatutory stock options.

     Automatic  Grants.  The Equity Plan  provides for the  automatic  grants of
options  to  purchase  shares of Common  Stock of the  Company  to  non-employee
directors. Pursuant to the terms of the Equity Plan:

                  1. Each  person  who is  elected  for the  first  time to be a
         non-employee  director shall,  upon the date of his initial election by
         the  Board or  stockholders,  automatically  be  granted  an  option to
         purchase 20,000 shares of the Company's Common Stock on such date.

                  2. Each  non-employee  director who serves on the Board on the
         final  vesting  date of an option that was  automatically  granted upon
         such person's election as a non-employee  director shall  automatically
         be granted an option to purchase 10,000 shares of the Company's  Common
         Stock on such date.

         Term.  Non-Employee  Director  Options under the Equity Plan have a ten
year term; however, each such option will terminate prior to the expiration date
if the optionee's service as a non-employee director terminates.  In that event,
the Non-Employee Director Option will terminate twelve months following the date
of  termination  of  service,  unless the  termination  of service is due to the
optionee's  death or disability,  in which case the option will terminate on the
earlier of the  expiration  date or eighteen  months  following  the date of the
optionee's death or disability.  The term of a Non-Employee  Director Option may
be extended if exercise within the periods is prohibited for specified reasons.

         Exercise  Price;  Payment.  The  exercise  price  of each  Non-Employee
Director  Option under the Equity Plan must be equal to the fair market value of
the Company's  Common Stock on the date of grant.  Payment of the exercise price
is due in full in cash at the time of exercise  when the number of shares  being
purchased is less than 1,000 shares;  when the number of shares being  purchased
is 1,000 or more shares, the optionee may elect to make payment under one of the
following  alternatives:  (i) in cash at the time of  exercise;  (ii) payment by
delivery of shares of the  Company's  Common Stock already owned by the optionee
for at least six  months;  or (iii)  payment  by a  combination  of the  methods
specified above.

         Exercise. Non-Employee Director Options under the Equity Plan generally
become exercisable in sixty equal monthly  installments after the date of grant.
However, an option granted to a person upon his election for the first time as a
non-employee  director  will become  exercisable  as  follows:  20% on the first
anniversary  of that  director's  election  and the  balance  in  equal  monthly
installments  ever the next forty-eight  months.  Subject to the satisfaction of
certain  conditions,  each  option  will be  exercisable  with  respect  to each
installment on or after the date of vesting applicable to such installment.


                                       17
<PAGE>

ADJUSTMENTS UPON CHANGES IN STOCK

         If any change is made in the Common  Stock  subject to the Equity Plan,
or subject to any Stock Award,  without receipt of  consideration by the Company
(through  merger,   consolidation,   reorganization,   recapitalization,   stock
dividend,  dividend  in  property  other than  cash,  stock  split,  liquidating
dividend,  combination  of  shares,  exchange  of  shares,  change in  corporate
structure or  otherwise),  the class and maximum number of shares subject to the
Equity Plan, the maximum annual award  applicable  under the Equity Plan and the
class and number of shares and price per share of stock  subject to  outstanding
Stock Awards will be appropriately adjusted.

         In the event of: (1) a dissolution or liquidation of the Company; (2) a
merger or consolidation  in which the Company is not the surviving  corporation;
(3) a reverse merger in which the Company is the surviving  corporation  but the
shares of the  Company's  Common Stock  outstanding  immediately  preceding  the
merger are converted by virtue of the merger into other property, whether in the
form of securities,  cash or otherwise;  or (4) any other capital reorganization
in which  more  than  50% of the  shares  of the  Company  entitled  to vote are
exchanged, then, at the sole discretion of the Board and to the extent permitted
by applicable law: (i) any surviving  corporation  shall assume any Stock Awards
outstanding  under the Equity Plan or shall substitute  similar Stock Awards for
those  outstanding  under the Equity Plan, (ii) such Stock Awards shall continue
in full force and effect, or (iii) any outstanding  unexercised rights under any
Stock Awards shall be terminated if not exercised prior to such event; provided,
however,  that with  respect to Stock  Awards  then held by  persons  performing
services for the Company or an affiliate the time during which such Stock Awards
become  vested  or  may  be  exercised  shall  be  accelerated   prior  to  such
termination.

         In the event a change of control (as hereinafter defined) occurs at the
Company and,  within one (1) year of such change in control,  (i) an  optionee's
employment with the Company or its affiliates is terminated other than for cause
(as hereinafter  defined), or (ii) a non-employee  director's  directorship with
the Company is terminated by the Company or by the Non-Employee Director for any
reason or for no reason,  options held by such  terminated  employee or director
may be  exercised  in full  following  such  termination  without  regard to the
vesting  limitations  to which  such  options  are  otherwise  subject.  For the
purposes of the foregoing,  a "change in control" shall have occurred if (1) any
person (as defined in Section 13 of the Exchange  Act)  acquires  shares,  other
than directly from the Company,  and thereby  becomes the owner of more than 30%
of the  Company's  outstanding  shares  (on a fully  diluted  basis)  or (2) the
Company  enters  into a merger  (other than one in  connection  with a voluntary
change of  corporate  domicile  or similar  reorganization  or  recapitalization
transaction) in which the  stockholders of the Company  (determined  immediately
prior to the  merger) do not own at least 50% of the  outstanding  shares of the
surviving entity after the merger. For purposes of the foregoing,  a termination
shall be  deemed  to have been  made for  "cause"  in the  event the  optionee's
employment is terminated  for any of the following  reasons:  (A) the optionee's
continued  failure to  substantially  perform his duties with the Company or its
affiliates,  (B) the engaging by the optionee in gross misconduct materially and
demonstrably  injurious to the Company,  its affiliates or their employees,  (C)
illicit drug use or habitual  alcohol use, or (D) the commission by the optionee
of any felony.

AMENDMENT OF THE PLAN

         The Board at any  time,  and from  time to time,  may amend the  Equity
Plan.   However,  no  amendment  shall  be  effective  unless  approved  by  the
stockholders  of the  Company  within  twelve  (12)  months  before or after the
adoption of the  amendment,  where the  amendment  will  increase  the number of
shares reserved for issuance under the Equity Plan,  modify the  requirements as
to  eligibility  for  participation  or in any  other  way if such  modification
requires  stockholder  approval  in order for the  Equity  Plan to  satisfy  the
requirements  of Section 422 of the Code or to comply with the  requirements  of
Rule 16b-3 of the Exchange Act. The Board may in its sole discretion  submit any
other amendment to the Equity Plan for stockholder approval.


                                       18
<PAGE>

TERMINATION OR SUSPENSION OF THE PLAN

         The Board may suspend or  terminate  the Equity  Plan at any time.  The
Equity Plan will  terminate on February 2, 2007 if this  proposal is approved by
the stockholders. No Stock Awards may be granted under the Equity Plan while the
Equity Plan is suspended or after it is terminated.

FEDERAL INCOME TAX INFORMATION

         Incentive Stock Options.  Incentive stock options under the Equity Plan
are  intended to be eligible  for the  favorable  federal  income tax  treatment
accorded "incentive stock options" under the Code.

         There generally are no federal income tax  consequences to the optionee
or the Company by reason of the grant or exercise of an incentive  stock option.
However,  the exercise of an incentive  stock option may increase the optionee's
alternative minimum tax liability, if any.

         If an optionee  holds stock acquired  through  exercise of an incentive
stock  option  for at least two (2) years  from the date on which the  option is
granted  and at least  one (1)  year  from the  date on  which  the  shares  are
transferred  to the optionee upon exercise of the option,  any gain or loss on a
disposition of such stock will be long-term capital gain or loss. Generally,  if
the  optionee  disposes of the stock  before the  expiration  of either of these
holding periods (a "disqualifying disposition"), at the time of disposition, the
optionee  will realize  taxable  ordinary  income equal to the lesser of (a) the
excess  of the  stock's  fair  market  value  on the date of  exercise  over the
exercise price,  or (b) the optionee's  actual gain, if any, on the purchase and
sale.  The  optionee's  additional  gain,  or any loss,  upon the  disqualifying
disposition  will be a  capital  gain  or  loss,  which  will  be  long-term  or
short-term  depending  on  whether  the  stock  was held for more than one year.
Capital gains  currently are generally  subject to lower tax rates than ordinary
income. The maximum long-term capital gains rate for federal income tax purposes
is currently 28% while the maximum ordinary income rate is effectively  39.6% at
the present time.  Slightly  different  rules may apply to optionees who acquire
stock subject to certain  repurchase options or who are subject to Section 16(b)
of the Exchange Act.

         To the extent the optionee  recognizes  ordinary  income by reason of a
disqualifying  disposition,  the Company will generally be entitled  (subject to
the  requirement  of  reasonableness  and the  satisfaction  of a tax  reporting
obligation) to a  corresponding  business  expense  deduction in the tax year in
which the disqualifying disposition occurs.

     Nonstatutory  Stock Options.  Nonstatutory  stock options granted under the
Equity Plan generally have the following federal income tax consequences:

         There are no tax  consequences to the optionee or the Company by reason
of the grant of a  nonstatutory  stock option.  Upon exercise of a  nonstatutory
stock option, the optionee normally will recognize taxable ordinary income equal
to the excess of the stock's fair market value on the date of exercise  over the
option  exercise  price.  With  respect to  employees,  the Company is generally
required to withhold from regular wages or supplemental  wage payments an amount
based on the ordinary income recognized. Generally, the Company will be entitled
to a business expense deduction equal to the taxable ordinary income realized by
the optionee.  Upon  disposition  of the stock,  the optionee  will  recognize a
capital gain or loss equal to the  difference  between the selling price and the
sum of the amount  paid for such stock plus any amount  recognized  as  ordinary
income upon exercise of the option. Such gain or loss will be long or short-term
depending  on  whether  the  stock  was held for more  than one  year.  Slightly
different  rules may apply to  optionees  who acquire  stock  subject to certain
repurchase options or who are subject to Section 16(b) of the Exchange Act.


                                       19
<PAGE>

         Restricted  Stock Purchase Awards and Stock Bonuses.  Restricted  stock
purchase  awards and stock bonuses  granted under the Equity Plan generally have
the following federal income tax consequences:

         Upon  acquisition of the stock,  the recipient  normally will recognize
taxable  ordinary  income  equal to the excess of the stock's  fair market value
over the purchase price, if any. However,  to the extent the stock is subject to
certain types of vesting  restrictions,  the taxable event will be delayed until
the  vesting  restrictions  lapse  unless  the  recipient  elects to be taxed on
receipt of the  stock.  With  respect to  employees,  the  Company is  generally
required to withhold from regular wages or supplemental  wage payments an amount
based on the ordinary income recognized. Generally, the Company will be entitled
to a business expense deduction equal to the taxable ordinary income realized by
the optionee.  Upon  disposition  of the stock,  the optionee  will  recognize a
capital gain or loss equal to the  difference  between the selling price and the
sum of the amount  paid for such stock plus any amount  recognized  as  ordinary
income upon  acquisition  (or  vesting) of the stock.  Such gain or loss will be
long or  short-term  depending  on whether  the stock was held for more than one
year.  Slightly different rules may apply to optionees who acquire stock subject
to  certain  repurchase  options  or who are  subject  to  Section  16(b) of the
Exchange Act.

         Other Tax  Consequences.  The  foregoing  discussion  is not a complete
description  of the federal income tax aspects of Stock Awards granted under the
Equity Plan. In addition,  administrative  and judicial  interpretations  of the
application of the federal income tax laws are subject to change. Furthermore no
information  is  given  with  respect  to  state  or  local  taxes  that  may be
applicable.

         Potential  Limitation  on Company  Deductions.  As part of the  Omnibus
Budget  Reconciliation  Act of 1993, the U.S.  Congress  amended the Code to add
Section  162(m) which denies a deduction to any  publicly-held  corporation  for
compensation  paid to certain  employees  in a taxable  year to the extent  that
compensation  exceeds $1 million for a covered  employee.  It is  possible  that
compensation attributable to awards granted in the future under the Equity Plan,
when  combined  with all  other  types of  compensation  received  by a  covered
employee  from the  Company,  may cause this  limitation  to be  exceeded in any
particular year.

         Certain kinds of compensation,  including qualified  "performance-based
compensation,"  are  disregarded  for purposes of the deduction  limitation.  In
accordance with Treasury  regulations issued under Section 162(m),  compensation
attributable  to stock options will qualify as  performance-based  compensation,
provided that the option is granted by a compensation committee comprised solely
of "outside  directors" and either:  (i) the option plan contains a per-employee
limitation  on the number of shares for which  options  may be granted  during a
specified period,  the per-employee  limitation is approved by the stockholders,
and the  exercise  price of the option is no less than the fair market  value of
the stock on the date of grant;  or (ii) the option is granted (or  exercisable)
only  upon  the  achievement  (as  certified  in  writing  by  the  compensation
committee)  of an  objective  performance  goal  established  in  writing by the
compensation  committee while the outcome is  substantially  uncertain,  and the
option is approved by stockholders.

The Board of Directors unanimously recommends a vote FOR proposal 2.

                                   PROPOSAL 3
                      RATIFICATION OF INDEPENDENT AUDITORS

         Upon  recommendation of the Audit Committee,  the Board of Directors of
the Company appointed  Coopers & Lybrand L.L.P. to be the Company's  independent
auditors for the fiscal year ending December 31, 1997.

         Services  provided  to the Company  and its  subsidiaries  by Coopers &
Lybrand  with  respect  to the fiscal  year ended  December  31,  1996  included
examination of the Company's consolidated financial statements,  limited reviews
of  quarterly   reports,   services   related  to  filings  with  the  SEC,  and
consultations concerning information systems and various tax matters.


                                       20
<PAGE>

         Coopers  & Lybrand  has  audited  the  Company's  financial  statements
annually  since the Company's  inception in 1982.  Representatives  of Coopers &
Lybrand are expected to be present at the Annual Meeting.  They do not expect to
make a  statement,  but will have the  opportunity  to make a statement  if they
desire to do so and will be available to respond to appropriate questions.

         Stockholder  ratification  of the selection of Coopers & Lybrand as the
Company's  independent  auditors  is not  required  by the  Company's  Bylaws or
otherwise.  However,  the Board is submitting the selection of Coopers & Lybrand
to the stockholders for ratification as a matter of good corporate practice.  If
the  stockholders  fail to ratify  this  selection,  the Board  will  reconsider
whether or not to retain that firm. Even if the selection is ratified, the Board
in  its  discretion  may  direct  the  appointment  of a  different  independent
accounting  firm at any time  during  the year if the  Board  feels  that such a
change would be in the best interests of the Company and its stockholders.

         Ratification  of the  selection  of Coopers & Lybrand as the  Company's
independent  auditors for fiscal year 1997 will require the affirmative  vote of
at least a majority of the shares of Common  Stock  represented  in person or by
proxy and entitled to vote at the Annual Meeting.

The Board of Directors unanimously recommends a vote FOR Proposal 3.

                                   PROPOSAL 4
                              STOCKHOLDER PROPOSAL:
             Appointment of Committee to Seek Buyer for the Company

         The Company has received a proposal  submitted  by Stanley B. Price,  7
Neptune  Drive,  Mary Esther,  Florida  32569,  who has indicated that he is the
beneficial  owner of 4,500 shares of the Company's  Common  Stock.  The Board of
Directors  disclaims any  responsibility for the content of the proposal and the
accompanying  supporting  statement,  which are  presented as received  from the
stockholder. The proposal is as follows:

                  "RESOLVED, that the stockholders of Scios Inc. (the `Company')
         hereby request that the Board of Directors of the Company (the `Board')
         take the steps necessary to appoint a special committee for the purpose
         of carrying out an  exhaustive  search for a buyer of the Company.  The
         committee's  activities  would  include  but  not be  limited  to:  (i)
         soliciting,  reviewing and negotiating offers to acquire the Company in
         [sic] terms that are fair and in the best  interests  of the  Company's
         stockholders,   and  that  maximize  the  value  of  the  stockholders'
         investment   in  the  Company,   and  (ii)   providing   the  Company's
         stockholders with quarterly reports on the committee's progress."

Supporting Statement of Stockholder

         "I believe that there is significant inherent value in the Company that
has been  unrecognized by the Company's current  management,  and that the Board
should  take  active  measures  to  maximize  the  value  of  the  stockholders'
investment in the Company by seeking a buyer for the Company. I believe that the
creation of a special  committee  to solicit  offers for the Company  would best
accomplish  this goal,  and that a VOTE FOR THIS  PROPOSAL  would best serve the
interests of stockholders."

Opposing Statement of the Board of Directors

         It is the  Board's  strong  belief that the  adoption of the  foregoing
proposal is not in the best  interests of the Company's  stockholders  and that,
rather than  maximizing  stockholder  value,  its adoption would actually reduce
stockholder  value.  In  recommending  a vote  against the  proposal,  the Board
recognizes  that  its  inherent   mandate  is  to  maximize  the  value  of  the
stockholders' investment.


                                       21
<PAGE>

         The  proposal   would   direct  the  Board  to  pursue  one   strategic
alternative:  to put the  Company  up for  sale.  The Board  believes  that this
proposal to put the Company "in play" without a strategic plan is inherently bad
business. If the Board is forced to function under a stockholder-imposed mandate
to sell the Company,  the Board's  ability to negotiate in confidence and from a
position  of  strength  will be  seriously  compromised.  At the same time,  the
uncertainty  about the  Company's  future  would be likely to  adversely  impact
business  and  operations  as a result  of the loss of  potential  and  existing
corporate partners, customers, vendors, key employees and others. This is likely
to  lead  to  unnecessary  stock  price  volatility  and  seriously   compromise
day-to-day  management  of the Company.  The Board  believes that a forced sale,
rather than adding value for  stockholders,  would  actually  decrease value for
stockholders.

         A nearly  identical  proposal was submitted to stockholder vote at both
the 1996 and 1994 annual meetings of stockholders. These proposals were defeated
by a vote of  approximately  87% of shares voting at the 1996 meeting and 83% of
shares  voting  at the 1994  meeting.  The Board  believes  that  these  earlier
rejections  by  stockholders  demonstrate  that  the  overwhelming  majority  of
stockholders  are aligned with the Board in its assessment that this proposal is
not in the best interest of stockholders.  In addition,  the Board believes that
the  current  proposal  is  particularly  ill-timed  in  view  of the  Company's
expectation that it will be able to announce the results of its pivotal clinical
trials for both  AURICULIN(R)  anaritide and NATRECOR(R) BNP later this year and
that these results may have a major impact on stockholder value.

         The Board and the  Company's  management  will continue to consider all
opportunities  for increasing  stockholder  value.  Currently,  six out of seven
members of the Board are independent directors.  The proposal is not clear as to
why the  Board as a whole  cannot  deal with such  matters,  as it now does.  In
summary, the Board and management believe that by dictating emphasis on a single
course of action the proposal is  counterproductive  to stockholders'  interests
and, if  approved,  would serve only to inhibit  the Board and  management  from
pursuing their main objective: to maximize stockholder value.

The Board of Directors unanimously recommends a vote AGAINST Proposal 4.

                                   PROPOSAL 5
                              STOCKHOLDER PROPOSAL:
                        Independent Chairman of the Board

         This proposal was submitted by Don L. Jacks,  P.O. Box 2557, Ft. Walton
Beach, Florida 32549-2557,  who has indicated that he is the beneficial owner of
1,000 shares of the Company's Common Stock. The Board of Directors disclaims any
responsibility  for the content of the proposal and the accompanying  supporting
statement, which are presented as received from the stockholder. The proposal is
as follows:

                  "RESOLVED, that the stockholders of the Company recommend that
         the Board of  Directors  take  appropriate  steps to  require  that the
         Chairman  of the  Board  be an  `Independent  Director.'  For  purposes
         hereof,  `Independent  Director' means a director who: (i) has not been
         employed  by the  Company as an  executive  within the last five years;
         (ii) is not, and is not affiliated with an entity that is an adviser or
         consultant  to  the  Company  [sic];  (iii)  is not  affiliated  with a
         significant  customer or supplier of the Company;  (iv) has no personal
         services  contracts  with the  Company;  (v) is not  affiliated  with a
         not-for-profit entity that receives significant  contributions from the
         Company;  (vi)  within the last five  years,  has not had any  business
         relationship  with the Company  that the  Company has been  required to
         disclose  publicly;  (vii) is not employed by a public company at which
         an executive  officer of the Company  serves as a director;  (viii) has
         not had a  relationship  described in (i) through  (vii) above with any
         affiliate  of the  Company;  and (ix) is not a member of the  immediate
         family of any person described in (i) through (viii) above."

Supporting Statement of Stockholder

         "I submit this  proposal  for an  independent  Chairman of the Board in
order to promote strong, objective leadership on the Board.


                                       22
<PAGE>

         A board of  directors  must  formulate  corporate  policies and monitor
management's  implementation  of those  policies.  The  Chairman of the Board is
responsible for leading the Board and helping to maintain the integrity of Board
decision-making  processes,  including,  among other things, setting agendas and
presiding at Board  meetings,  and ensuring that  directors  are given  adequate
information.  I strongly  believe that the Chairman also should take a lead role
in evaluating the performance of management. In my view, an independent Chairman
would best perform this function and would serve the interests of  stockholders,
rather than the interests of incumbent management.

         The benefits of independent directors are generally well accepted.  The
New York Stock Exchange, for example,  requires that at least two members of the
board of a listed  company,  and all members of the company's  audit  committee,
must meet the Exchange's  standards of independence.  The Investment Company Act
of 1940 (the law that  governs the  activities  of  investment  companies)  also
includes an  independent  director  provision,  generally  requiring  investment
company boards to be comprised of at least 40 percent `disinterested' directors.

         I believe that a board of directors functions best when its Chairman is
an independent director, and that a VOTE FOR THIS PROPOSAL will help provide the
Board with the leadership necessary to address the needs of stockholders."

Opposing Statement of the Board of Directors

         Six of the seven members of the Board,  including all members of all of
the committees of the Board, are independent (non-management) directors. Each of
the  non-management  directors  is a full  participant  in the  Company's  major
strategic and policy  decisions.  As a result,  the  independence  necessary for
effective Board  oversight of management,  which is the purpose of the proposal,
already  exists at  Scios.  With six of seven  members  being  independent,  the
composition of the Board and its committees  more than satisfies the independent
director  requirements  under the  rules  cited by the  proponent  (to which the
Company is not  subject),  as well as the rules of the National  Association  of
Securities Dealers (with which the Company must comply). A recent study covering
435 companies in the S&P 500 reported that only seven of these  companies  (less
than 2%) had an independent Chairman of the Board.

         The   responsibilities  of  the  Nominating,   Audit  and  Compensation
Committees of the Board are described earlier in this Proxy Statement. It is the
opinion  of the board  that the key  roles  played  by these  committees  in the
functioning of the Board make a  non-management  Chairman  unnecessary at Scios.
The  Compensation  Committee  determines  executive  compensation  policies  and
evaluates the  performance of the Chief  Executive  Officer and other  executive
officers.  The Nominating  Committee  recommends director candidates to the full
Board.  The  Audit  Committee  provides  oversight  on the  Company's  financial
practices.  The  Chairman/CEO  is not a member of any of these  committees.  The
Board believes that no meaningful  additional  measure of independence  would be
provided by a non-management  Chairman.  There is no conflict of interest caused
by the offices of the Chairman and CEO being held by one person.

         The  Board's  view  is that  it is  unwise  to  impose  the  proposal's
inflexible rule that under all possible  circumstances and at all times the same
person must never be both Chairman and CEO. In addition, the Board believes that
it could cost the  Company at least  $75,000  per year to employ an  independent
Chairman,  even on a part-time  basis,  and does not believe  that the  benefits
suggested  by  the  proponent  justify  this  additional  compensation  expense.
Finally,  the Board  believes  that it is  important  to maintain the ability to
respond to changing  circumstances,  rather than  adopting the rigid  mandate of
this proposal.

     An identical  proposal submitted to stockholder vote in 1994 was opposed by
86% of the shares eligible to vote.

The Board of Directors unanimously recommends a vote AGAINST Proposal 5.


                                       23
<PAGE>

                                   PROPOSAL 6
                              STOCKHOLDER PROPOSAL:
                         Shareholder Advisory Committee

         The Company has received a proposal  submitted  by Karl B.  Didricksen,
8361 Calle del Cielo, La Jolla,  California  92037, who has indicated that he is
the beneficial owner of 1,000 shares of the Company's Common Stock. The Board of
Directors  disclaims any  responsibility for the content of the proposal and the
accompanying  supporting  statement,  which are  presented as received  from the
stockholder. The proposal is as follows:

                  "RESOLVED,  that Scios Inc. shall have a shareholders advisory
         committee  to  advise  the  board  of  directors  on the  interests  of
         shareholders.  The board of directors  shall ensure the  formation  and
         effective  operation of this committee and shall give due consideration
         to such advice and proposals as shall be reported by this  committee to
         the board.  Members of the  committee  shall serve without costs to the
         company,  except  that the  committee  shall be  reimbursed  for normal
         travel and operating  expenses.  The committee  shall be composed of at
         least five members and shall be  reconstituted  on an annual basis. The
         board shall establish appropriate  procedures for selection of members,
         provided  that (1) each member is a beneficial  owner of at least 1,000
         shares  of  the  company's  voting  stock  for  the  entire  period  of
         membership,  (2) no member has any  affiliation  with the company other
         than as a  shareholder.  No member may serve more than two  consecutive
         terms."

Supporting Statement of Stockholder

         "As a shareholder with long term investment objectives,  I believe that
the decisions of the board of directors should be made with due consideration of
the view of shareholders. However, there is currently no organized forum through
which  shareholders  can express those views.  This proposal would  establish an
advisory   committee  and   institutionalize  a  procedure  for  developing  and
communicating  shareholder input. I believe that this structure will benefit the
company by assuring that the board is aware of the  perspective of  shareholders
as it makes its decisions.  The  shareholder  advisory  committee  would have no
authority to bind or act on behalf of the company. It would operate solely in an
advisory capacity.  Furthermore,  this proposal will not restrict the ability of
the board of directors to take  whatever  actions it deems best for the company.
The committee structure merely creates a means to enable such actions to be with
full  consideration of the views of stockholders.  By supporting my proposal,  I
believe  shareholders  will help ensure that the directors will be in a position
to make decisions with a better understanding of the interests of shareholders."

Opposing Statement of the Board of Directors

         The Board is elected by all  stockholders  and is charged with ensuring
that the  business and affairs of the Company are managed for the benefit of all
stockholders  through the  exercise of its business  judgment.  The views of the
stockholders  are carefully  considered by the Board as it carries out its legal
duty  of  care  owed  to  all  stockholders.  The  Company  communicates  to all
stockholders  on a  regular  basis  and  believes  that the  proposal  would add
unnecessary cost by duplicating existing management procedures for communicating
with stockholders.

         The Board  believes  that the  proposal,  if adopted,  would  create an
expensive, complex and inflexible structure. Among other things, it could compel
the  Company  to  engage  in a  complicated  nomination  process  and to pay all
expenses  related  to  the  undefined  activities  of  the  proposed  committee.
Furthermore,  it is likely to be  difficult to recruit  stockholders  willing to
serve on the  committee.  At times it may be  necessary to disclose to committee
members  information  that has not yet been made  public by the  Company,  which
would  make the  members  "insiders."  As a  result,  they  would not be able to
conduct any  transactions in Company stock until the information is made public.
In  addition,  one or more of  stockholders  willing to serve could have special
interests or motives  contrary to the interests of the  stockholders in general.
Other stockholders,  who, in the aggregate,  may own a majority of the Company's
stock, could be excluded altogether.


                                       24
<PAGE>

         The Board of  Directors  owes a duty to  consider  the  welfare  of all
stockholders,  and the Board  believes  the proposed  committee  will divert the
Board's attention from that task. More  importantly,  by duplicating the Board's
existing  efforts to  communicate  with and to consider  the views of all of its
stockholders,  the Board  believes the  proposal,  if enacted,  would divert the
attention of the Board from its primary task,  which is to see that the business
and affairs of the Company are run as effectively as possible.  In summary,  the
Board strongly believes that the proposal, if enacted, could compromise existing
stockholder   communications  procedures  and  waste  the  Company's  human  and
financial  resources for the benefit of only few select  stockholders  who might
serve on the  committee.  The  Board  believes  that  stockholder  communication
committees have not been established by other companies  because of the numerous
issues implicit in their use and maintenance.

The Board of Directors unanimously recommends a vote AGAINST Proposal 6.

                                  OTHER MATTERS

         The Board of  Directors  does not know of other  matters  that may come
before the meeting.  However, if any other matters are properly presented to the
meeting,  it is the intention of the persons named in the accompanying  proxy to
vote, or otherwise to act, in accordance with their judgment on such matters.

                   STOCKHOLDER PROPOSALS - 1998 ANNUAL MEETING

         Stockholders  are  entitled  to  present  proposals  for  action  at  a
forthcoming  stockholder  meeting if they  comply with the  requirements  of the
proxy rules.  Proposals of stockholders that are intended to be presented at the
Company's 1998 Annual Meeting of Stockholders must be received by the Company no
later than November 30, 1997 in order to be included in the proxy  statement and
proxy relating to that meeting.

                                  By Order of the Board of Directors

                                  JOHN H. NEWMAN
                                  Secretary

March 31, 1997

THE BOARD OF DIRECTORS HOPES THAT STOCKHOLDERS WILL ATTEND THIS MEETING. WHETHER
OR NOT YOU PLAN TO  ATTEND,  YOU ARE  URGED TO  COMPLETE,  SIGN AND  RETURN  THE
ENCLOSED PROXY IN THE ACCOMPANYING ENVELOPE. STOCKHOLDERS WHO ATTEND THE MEETING
MAY VOTE THEIR SHARES PERSONALLY EVEN THOUGH THEY HAVE SENT IN THEIR PROXIES.


                                       25
<PAGE>


                                  DETACH HERE


                                   SCIOS INC.

              PROXY FOR ANNUAL MEETING OF STOCKHOLDERS MAY 13, 1997

           THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

P
R
O          The undersigned hereby appoints Richard L. Casey and John H. Newman,
X     or either of them, each with full power of substitution, as proxies
Y     of the undersigned, to attend the Annual Meeting of Stockholders of
      Scios Inc., to be held at the offices of the Company, 2450 Bayshore
      Parkway, Mountain View, California, on May 13, 1997 at 10:00 a.m. and at
      any adjournment or postponement thereof, to vote the number of shares
      the undersigned would be entitled to vote if personally present, and to
      vote in their discretion upon any other business that may properly come
      before the meeting.

            THIS PROXY WHEN PROPERLY EXECUTED WILL BE VOTED IN THE MANNER
      DIRECTED HEREIN. IF NO DIRECTION IS MADE, THIS PROXY WILL BE VOTED FOR
      PROPOSALS 1, 2 AND 3 AND AGAINST PROPOSALS 4, 5 AND 6.

            Please sign, date and return this proxy in the envelope provided,
       which requires no postage if mailed in the United States.


                                                             ___________

                                                             SEE REVERSE
             CONTINUED AND TO BE SIGNED ON REVERSE SIDE         SIDE
                                                             ___________





<PAGE>



                                 DETACH HERE

      PLEASE MARK
/ X / VOTES AS IN
      THIS EXAMPLE

- -------------------------------------------------------------------------------
       The Board of Directors recommends a vote FOR Proposals 1, 2 and 3.
- --------------------------------------------------------------------------------
1. Election of Directors.
NOMINEES: Samuel H. Armacost, Richard L. Casey, Myron Du Bain, Robert W.
Schrier, Burton E. Sobel, Solomon H. Snyder, Eugene L. Step

           FOR           WITHHELD                   MARK HERE
           / /             / /                      IF YOU PLAN
                                                    TO ATTEND
                                                    THE MEETING        / /
/ / __________________________________________
    For all nominees except as noted above
                                                    MARK HERE
                                                    FOR ADDRESS
                                                    CHANGE AND
                                                    NOTE BELOW         / /

2. To ratify and approve amendments to             FOR   AGAINST   ABSTAIN
   the Company's 1992 Equity Incentive Plan.       / /     / /        / /

3. To ratify the selection of Coopers &
   Lybrand LLP as the Company's independent        FOR    AGAINST   ABSTAIN
   auditors for fiscal 1997.                       / /      / /       / /

- --------------------------------------------------------------------------------
                    The Board of Directors recommends a vote
                   AGAINST stockholder proposals 4, 5 and 6.
- --------------------------------------------------------------------------------
4. Stockholder proposal to appoint                 FOR    AGAINST   ABSTAIN
   committee to seek buyer.                        / /      / /       / /

5. Stockholder proposal to require                 FOR    AGAINST   ABSTAIN
   independent chairman of the board.              / /      / /       / /

6. Stockholder proposal to form                    FOR    AGAINST   ABSTAIN
   shareholder advisory committee.                 / /      / /       / /


(Please sign exactly as name appears. When shares are held by joint tenants,
both should sign. When signing as attorney, as executor, administrator,
trustee or guardian, please give full title as such. If a corporation, please
sign in full corporate name by President or other authorized officer. If a
partnership, please sign in partnership name by authorized person.)



Signature:________________ Date:________ Signature:_________________ Date:_____




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