ENZON INC
DEF 14A, 1997-10-28
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                            SCHEDULE 14A INFORMATION

Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934
                                (Amendment No. )

Filed by the Registrant |x|
Filed by a Party other than the Registrant |_|

Check the appropriate box:

| | Preliminary Proxy Statement
| | Confidential, for Use of the Commission Only (as permitted by Rule 
    14a-6(e)(2))
|X| Definitive Proxy Statement
|_| Definitive Additional Materials
|_| Soliciting Material Pursuant to ss. 240.14a-11(c) or ss. 240.14a-12

                                  ENZON, INC.
                (Name of Registrant as Specified In Its Charter)

                             KEVIN T. COLLINS, ESQ.
     (Name of Person(s) Filing Proxy Statement if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):

|X| No Fee required
|_| Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.


1) Title of each class of securities to which transaction applies:

   _____________________________________________________________________________

2) Aggregate number of securities to which transaction applies:

   _____________________________________________________________________________

3) Per unit price or other underlying value of transaction computed
   pursuant to Exchange Act Rule 0-11 (Set forth the amount on which the filing
   fee is calculated and state how it was determined):

   _____________________________________________________________________________

4) Proposed maximum aggregate value of transaction:

   _____________________________________________________________________________

5) Total fee paid:

   _____________________________________________________________________________

|_| Fee paid previously with preliminary materials.

|_| Check box if any part of the fee is offset as provided by
    Exchange Act Rule 0-11(a)(2) and identify the filing for which
    the offsetting fee was paid previously.  Identify the previous
    filing by registration statement number, or the Form or Schedule
    and the date of its filing.

    1) Amount Previously Paid: _________________________________________________

    2) Form, Schedule or Registration Statement No. ____________________________

    3) Filing Party: ___________________________________________________________

    4) Date Filed: _____________________________________________________________



<PAGE>




                               [LOGO] ENZON, INC.

                               20 Kingsbridge Road
                          Piscataway, New Jersey 08854
                                 (732) 980-4500

                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                           TO BE HELD DECEMBER 2, 1997


To our Stockholders:

     You are hereby  notified  that the  annual  meeting  of  stockholders  (the
"Annual  Meeting")  of Enzon,  Inc.,  a  Delaware  corporation  ("Enzon"  or the
"Company")  will be held at the Embassy  Suites Hotel,  121  Centennial  Avenue,
Piscataway,  New Jersey on Tuesday,  December 2, 1997 at 10:00 a.m.  local time,
for the following purposes:

     1.   To elect two  Class II  directors,  each for a term of three  years in
          accordance with the Company's Certificate of Incorporation and By-Laws
          (Proposal No. 1);

     2.   To  vote  on  a  proposal  to  amend  the  Company's   Certificate  of
          Incorporation  to increase the number of  authorized  shares of Common
          Stock from forty million  (40,000,000)  to sixty million  (60,000,000)
          (Proposal No. 2);

     3.   To vote  on a  proposal  to  approve  an  amendment  to the  Company's
          Non-Qualified  Stock  Option  Plan,  as amended to conform the Plan to
          changes made to the rules under  Section 16(b) of the  Securities  and
          Exchange Act of 1934 (Proposal No. 3);

     4.   To  ratify  the  selection  of  KPMG  Peat  Marwick  LLP,  independent
          certified  public  accountants,  to audit the  consolidated  financial
          statements  of the  Company  for the fiscal  year ending June 30, 1998
          (Proposal No. 4); and

     5.   To transact  such other matters as may properly come before the Annual
          Meeting or any adjournment thereof.

     Only holders of record of the Company's  Common  Stock,  par value $.01 per
share, and Series A Cumulative  Convertible  Preferred Stock, par value $.01 per
share,  at the close of business  on October 27, 1997 are  entitled to notice of
and to vote at the Annual Meeting.

     Enzon hopes that as many  stockholders as possible will  personally  attend
the Annual Meeting. Whether or not you plan to attend the Annual Meeting, please
complete the enclosed  proxy card and sign,  date and return it promptly so that
your shares will be represented. Sending in your proxy will not prevent you from
voting in person at the Annual Meeting.

                                   By order of the Board of Directors,


                                   /s/ John A. Caruso
                                   John A. Caruso, Secretary


Piscataway, New Jersey
October 31, 1997



<PAGE>



                                   ENZON, INC.
                                     -------

                                 PROXY STATEMENT
                                     -------

     This Proxy  Statement is furnished in connection  with the  solicitation of
proxies for use at the annual meeting of stockholders  (the "Annual Meeting") of
Enzon, Inc.  ("Enzon" or the "Company") to be held on Tuesday,  December 2, 1997
and at any adjournment thereof. The accompanying proxy is solicited by the Board
of Directors of the Company and is revocable by the  stockholder any time before
it is voted.  For more  information  concerning  the  procedure for revoking the
proxy see "General."  This Proxy  Statement was first mailed to  stockholders of
the Company on or about October 31, 1997,  accompanied  by the Company's  Annual
Report to  Stockholders  for the fiscal year ended June 30, 1997.  The principal
executive offices of the Company are located at 20 Kingsbridge Road, Piscataway,
New Jersey 08854, telephone (732) 980-4500.


                      OUTSTANDING SHARES AND VOTING RIGHTS

     Only holders of the Company's  common stock,  par value $.01 per share (the
"Common Stock" or "Common Shares") and Series A Cumulative Convertible Preferred
Stock,  $.01 per share (the  "Series A  Preferred  Stock" or "Series A Preferred
Shares")  outstanding  at the close of business on October 27, 1997 (the "Record
Date") are entitled to receive notice of and vote at the Annual  Meeting.  As of
the Record Date, the number and class of stock that was  outstanding and will be
entitled to vote at the meeting were 30,922,744 Common Shares and 108,000 Series
A Preferred  Shares.  Each Common Share and Series A Preferred Share is entitled
to one vote on all  matters.  No other class of  securities  will be entitled to
vote at the Annual Meeting. There are no cumulative voting rights.

     To be elected,  a director  must  receive a  plurality  of the votes of the
Common Shares and Series A Preferred Shares,  voting as a single class,  present
in person or  represented by proxy at the Annual Meeting and entitled to vote on
the election of directors.  The affirmative  votes of at least (i) a majority of
the Common  Shares and Series A Preferred  Shares  outstanding  as of the Record
Date, and entitled to vote thereon, voting together as a single class and (ii) a
majority of the Common Shares  outstanding as of the Record Date and entitled to
vote  thereon,  voting  separately  as a class,  are  necessary  for approval of
Proposal No. 2. The affirmative vote of at least a majority of the Common Shares
and Series A Preferred Shares,  present in person or represented by proxy at the
Annual Meeting and entitled to vote thereon,  voting together as a single class,
is  necessary  for  approval of Proposal  No. 3 and  Proposal No. 4. A quorum is
representation in person or by proxy at the Annual Meeting of at least one-third
of the combined  Common Shares and Series A Preferred  Shares  outstanding as of
the Record Date.

     Pursuant to the Delaware  General  Corporation Law, only votes cast "For" a
matter  constitute  affirmative  votes.  Proxy  cards which are voted by marking
"Withheld" or "Abstain" on a particular matter are counted as present for quorum
purposes and for purposes of determining  the outcome of such matter,  but since
they are not cast "For" a particular  matter,  they will have the same effect as
negative  votes or votes  cast  "Against"  a  particular  matter.  If a  validly
executed proxy card is not marked to indicate a vote on a particular  matter and
the proxy granted  thereby is not revoked  before it is voted,  it will be voted
"For" such matter.  Where brokers are prohibited from  exercising  discretionary
authority  for  beneficial  owners  who have not  provided  voting  instructions
(commonly  referred to as "broker  non-votes"),  such broker  non-votes  will be
treated as shares that are present for purposes of determining the presence of a
quorum; however, with respect to proposals which require the affirmative vote of
a percentage of shares present at the Annual  Meeting for approval,  such broker
non-votes will be treated as not present for purposes of determining the outcome
of any such matter. With respect to proposals which require the affirmative vote
of a  percentage  of the  outstanding  shares for  approval,  since such  broker
non-votes are not cast "For" a particular matter, they will have the same effect
as negative votes or votes cast "Against" such proposals.

                                      - 1 -

<PAGE>



                     PROPOSAL NO. 1 - ELECTION OF DIRECTORS

     Pursuant to the provisions of the Company's  Certificate  of  Incorporation
and By-laws,  the Board of Directors is comprised of three classes of directors,
designated  Class I, Class II and Class III.  One class of  directors is elected
each year to hold  office for a  three-year  term and until  successors  of such
directors are duly elected and qualified. Two Class II directors will be elected
at this  year's  Annual  Meeting.  The  nominees  for  election to the office of
director,  and certain  information  with respect to their  backgrounds  and the
backgrounds of non-nominee  directors,  are set forth below. It is the intention
of  the  persons  named  in  the  accompanying   proxy  card,  unless  otherwise
instructed,  to vote to elect the nominees  named herein as Class II  directors.
Each of the nominees named herein presently serves as a director of the Company.
In the event any of the nominees  named herein is unable to serve as a director,
discretionary  authority  is  reserved to the Board of  Directors  to vote for a
substitute.  The Board of  Directors  has no reason to  believe  that any of the
nominees named herein will be unable to serve if elected.

                 Nominees for Election to the Office of Director
                           at the 1997 Annual Meeting

                                        Director
Nominee                        Age      Since          Position with the Company
- -------                        ---      --------       -------------------------

Randy H. Thurman(1)             48      1993           Chairman of the Board

A.M. "Don" MacKinnon(1)(3)      73      1990           Director


                    Non-Nominee Directors Continuing to Serve
             in the Office of Director After the 1997 Annual Meeting

                                        Director
Nominee                        Age      Since          Position with the Company
- -------                        ---      --------       -------------------------

Peter G. Tombros (1)(4)         55      1994           President and Chief 
                                                       Executive Officer

Rolf A. Classon(2)(5)           52      1997           Director

Dr. Rosina B. Dixon (2)(4)      54      1994           Director

Robert LeBuhn (2)(3)(5)         66      1994           Director






(1)  Member of the Executive Committee

(2)  Member of the Compensation Committee

(3)  Member of the Audit Committee

(4)  Class I  director  serving  until  the 1999  Annual  Meeting  

(5)  Class III director serving until the 1998 Annual Meeting

                                      - 2 -

<PAGE>



                        BUSINESS EXPERIENCE OF DIRECTORS

Nominee Class II Directors for Election at the 1997 Annual Meeting

     Randy H. Thurman has served as the  non-executive  Chairman of the Board of
the Company  since April 1996 and as a Director of the Company since April 1993.
Since 1996,  Mr.  Thurman has been a principal at Spencer  Stuart,  an executive
search  consulting firm. Mr. Thurman is the founder and has been Chairman of the
Board of Health Care Strategies 2000, a global healthcare  consulting firm since
1995.  From 1993 to 1995,  Mr.  Thurman  served as chairman and chief  executive
officer of Corning  Life  Sciences.  From 1985 to 1993,  Mr.  Thurman  served as
corporate  executive vice president and a director of Rhone-Poulenc  Rorer, Inc.
and president of Rhone-Poulenc Rorer Pharmaceuticals, Inc. He also serves on the
Board of Directors of Onyx Pharmaceuticals and Closure Medical.

     A.M.  "Don"  MacKinnon  has served as a Director of the Company since 1990.
Mr.   MacKinnon  was  president  and  chief  operating   officer  of  Ciba-Geigy
Corporation from 1980 until his retirement in 1986. He was a member of the Board
of Directors of Ciba-Geigy  Corporation from 1970 until he reached the mandatory
retirement age in December  1994.  Over the last nine years,  Mr.  MacKinnon has
served on the Board of Directors of several biopharmaceutical companies.

     The Board of Directors  recommends a vote FOR Mr. Thurman and Mr. MacKinnon
as Class II Directors (Proposal No. 1 on the Proxy Card).

Non-Nominee Class I Directors Serving Until the 1999 Annual Meeting

     Peter G. Tombros has served as President and Chief Executive Officer of the
Company and a member of the board since April 1994.  Prior to joining Enzon, Mr.
Tombros  spent 25 years with Pfizer Inc., a research  based,  global  healthcare
company  headquartered in New York City. From 1986 to March 1994, he served as a
vice president of Pfizer Inc. in the following  areas:  executive vice president
of Pfizer  Pharmaceuticals,  a  division  of Pfizer  Inc.,  corporate  strategic
planning and investor relations. From 1980 to 1986, Mr. Tombros served as senior
vice  president  of Pfizer  Pharmaceuticals  and general  manager for the Roerig
division of Pfizer Inc. Mr. Tombros currently serves on the Board of Trustees of
Cancer Care and the National Cancer Care Foundation,  Dominican College and Fisk
University.  From 1980 to 1992, he was a director of the American  Foundation of
Pharmaceutical  Education  and served as Chairman for three of those years.  Mr.
Tombros serves on the Board of Directors of Alpharma Inc.,  formally A.L. Pharma
Inc.,  a  Norwegian  company   specializing  in  the  areas  of  animal  health,
pharmaceuticals and fine chemicals.

     Dr.  Rosina B. Dixon has served as a Director of the Company  since  August
1994. Dr. Dixon has been a consultant to the pharmaceutical industry since 1987.
Prior to such time she held senior  positions at Ciba-Geigy  Pharmaceuticals,  a
division  of  Ciba-Geigy  Corporation,   and  Schering-Plough  Corporation.  She
received her M.D. from Columbia  University,  College of Physicians and Surgeons
and is  certified by the National  Board of Medical  Examiners  and the American
Board of Internal Medicine.  She is a member of the American College of Clinical
Pharmacology,  American  Society for Clinical  Pharmacology and Therapeutics and
the  National  Association  of Corporate  Directors  and  currently  serves as a
director of Church & Dwight Co., Inc. and Cambrex Corporation.

Non-Nominee Class III Director Serving Until the 1998 Annual Meeting

     Robert  LeBuhn has served as a Director of the Company  since  August 1994.
Mr. LeBuhn was chairman of Investor  International (U.S.), Inc., a subsidiary of
Investor  A.B.,  part of  Sweden's  Wallenberg  Group  from June 1992  until his
retirement in September  1994,  and was its  president  from August 1984 through
June 1992. He is a former managing director of Rothschild,  Inc. Mr. LeBuhn is a
director of US Airways Group, Inc.,  Acceptance Insurance  Companies,  Inc., New
Jersey Steel Corporation and Cambrex Corporation.  He is president and a trustee
of the Geraldine R. Dodge Foundation.

     Rolf A. Classon has served as a Director of the Company since January 1997.
Mr. Classon is currently an Executive Vice  President of Bayer  Corporation  and
President of Bayer Diagnostics.  From 1991 to 1995, Mr. Classon was an Executive
Vice President in charge of Bayer Diagnostics'  Worldwide  Marketing,  Sales and
Service operations.

                                      - 3 -


<PAGE>



From 1990 to 1991,  Mr.  Classon was  President and Chief  Operating  Officer of
Pharmacia  Biosystems  A.B.  Prior to 1991,  Mr.  Classon served as president of
Pharmacia   Development  Company  Inc.  and  Pharmacia  A.B.  Hospital  Products
Division.

                             DIRECTORS' COMPENSATION

Directors' Cash Compensation

     During the  fiscal  year ended June 30,  1997,  the  Company  paid Randy H.
Thurman  $100,000 in  consideration  for  serving as Chairman of the Board.  The
Company did not pay cash  compensation to its remaining  directors for acting as
directors  or as members of  committees  of the Board of  Directors,  other than
reimbursement  of  reasonable  expenses  incurred by the  directors in attending
board and committee meetings.

Directors' Stock Options

     In December  1993,  the Board of Directors  adopted,  and the  stockholders
approved,  an amendment to the NonQualified Stock Option Plan, as amended,  (the
"Plan") providing for automatic grants of options  ("Automatic  Grants") under a
formula  (the  "Formula")  to  non-executive  members of the Board of  Directors
("Independent Directors").

     Under the Formula, Independent Directors automatically receive an option to
purchase 60,000 shares of Common Stock on each of the following  dates:  January
2,  1994,  January 2, 1997,  January 2, 2000 and  January 2, 2003 (the  "Regular
Grants").  On the date of each  Independent  Director's  initial election to the
board,  pursuant  to a vote of the  Company's  stockholders  or the board,  such
newly-elected  Independent  Director  automatically  receives  (i) an  option to
purchase such Independent  Director's pro rata share of the Regular Grant, which
equals the product of 1,666  multiplied by the number of whole months  remaining
in the relevant  three year period  until the next Regular  Grant (the "Pro Rata
Grant");  and (ii) an option to  purchase  10,000  shares of Common  Stock  (the
"Initial  Election  Grant").  Each  option  granted to an  Independent  Director
pursuant  to a Regular  Grant vests and becomes  exercisable  as follows:  as to
20,000  shares one year after the date of grant;  as to 20,000  shares two years
after the date of grant, and as to the remaining 20,000 shares three years after
the date of grant.  Those options granted  pursuant to a Pro Rata Grant vest and
become  exercisable  as to that  number of shares  equal to the product of 1,666
multiplied by the number of whole months remaining in the first calendar year in
which the Independent  Director is elected initially to the board on the January
1st following such Independent  Director's initial election to the board; and as
to any  remaining  shares in  accordance  with the schedule for options  granted
pursuant  to a Regular  Grant.  Those  options  granted  pursuant  to an Initial
Election Grant vest and become exercisable as to 5,000 shares one year after the
date of grant; and as to 5,000 shares two years after the date of grant. The per
share exercise price of options granted  pursuant to the Formula is equal to the
fair market value of the Common Stock on the date of grant.

     An option granted to an Independent  Director  pursuant to the Formula will
not  become  exercisable  as to the  relevant  shares  unless  such  Independent
Director has served continuously on the board during the year preceding the date
on which such options are scheduled to vest and become exercisable,  or from the
date such  Independent  Director  joined  the  board  until the end of such year
should  such  Independent  Director  have  joined  the board  during  such year;
provided,  however,  that if an  Independent  Director  does  not  fulfill  such
continuous  service  requirement  due to such  Independent  Director's  death or
disability  all options  granted under the Formula and held by such  Independent
Director  nonetheless  vest and become  exercisable  as though such  Independent
Director fulfilled the continuous service  requirement.  An option granted to an
Independent Director pursuant to the Formula remains exercisable for a period of
ten years from the date of grant.

     During May 1997,  the  Company  granted  A.M."Don"  MacKinnon  an option to
purchase  2,000  shares  of  the  Company's  Common  Stock  under  the  Plan  in
consideration  for additional  services  provided to the Company.  The per share
exercise price of the option is $2.69,  which was equal to the fair market value
of the  Common  Stock on the date of grant.  The option has a term of ten years.
The options are fully vested and will become exercisable on November 13, 1997.


                                      - 4 -



<PAGE>



Independent Directors' Stock Plan

     The Company's  1996  Independent  Directors'  Stock Plan (the  "Independent
Directors' Stock Plan") provides  compensation to Independent  Directors serving
on the board which is paid in the form of the Company's Common Stock. Other than
the Chairman of the Board,  Independent  Directors are not currently entitled to
receive cash  compensation.  Under the Independent  Directors'  Stock Plan, each
Independent  Director  is  entitled  to  compensation  equivalent  to $2,500 per
quarter and $500 for each meeting  attended by the board  member.  The number of
shares issued will be based on the last reported sale price of a share of Common
Stock on the NASDAQ National Market at the end of the quarter for which fees are
payable.  During the year ended June 30, 1997, the Company  recorded  $65,500 in
Independent  Directors' fees. The following is a summary of compensation paid to
the Independent Directors under the Independent Director Stock Plan:

                                      Value of           Number
                                    Consideration     of Shares
                                    -------------     ---------

       Randy H. Thurman              $14,500            5,743
       Rolf A. Classon                 7,500            3,117
       Dr. Rosina Dixon               14,500            5,743
       Robert LeBuhn                  14,500            5,743
       A.M. "Don" MacKinnon           14,500            5,743

Section 16(a) Beneficial Ownership Reporting Compliance

     Ownership of and transactions in the Company's stock by executive  officers
and  directors  of the  Company  and  owners  of 10% or  more  of the  Company's
outstanding  Common  Stock are  required to be reported  to the  Securities  and
Exchange  Commission pursuant to Section 16(a) of the Securities Exchange Act of
1934,  as amended.  During the year ended June 30,  1997,  all such reports were
filed in a timely manner.


               INFORMATION CONCERNING BOARD AND COMMITTEE MEETINGS
                           AND COMMITTEES OF THE BOARD

     Nine  meetings of the  Company's  Board of  Directors  were held during the
fiscal year ended June 30, 1997. Each incumbent  director  attended at least 75%
of the total number of meetings of the Board of Directors and any  committees of
the Board of  Directors  of which such  director  was a member  held  during the
fiscal year.

     As of June 30, 1997, the only standing committees of the Company's Board of
Directors  were  the  Audit  Committee,  Compensation  Committee  and  Executive
Committee.

     The Audit Committee is comprised of Robert LeBuhn, Chairman, and A.M. "Don"
MacKinnon.  The primary  functions of the Audit  Committee  are to meet with the
Company's  independent  auditors  to discuss  and review  audit  procedures  and
issues,  meet with  management on matters  concerning  the  Company's  financial
condition,  internal controls and year-end audit and report to the board on such
matters. The Audit Committee held two meetings during the fiscal year ended June
30, 1997.

     The   Compensation   Committee  is  comprised  of  Dr.   Rosina  B.  Dixon,
Chairperson,  Rolf A. Classon and Robert  LeBuhn.  The primary  functions of the
Compensation  Committee are to  administer  the  Company's  Non-Qualified  Stock
Option Plan,  determine the  compensation  of the Company's  officers and senior
management  and review  compensation  policy.  There were four  meetings  of the
Compensation Committee during the fiscal year ended June 30, 1997.

     The Executive Committee, comprised of A.M. "Don" MacKinnon, Chairman, Peter
G. Tombros, and Randy H. Thurman,  meets to review and make decisions concerning
matters which would  otherwise  come before the Board,  as permitted by Delaware
law and the Company's by-laws.  Given the relatively small size of the Company's
current Board of Directors,  the Company  determined that  efficiencies were not
being realized from meetings of the Executive Committee

                                      - 5 -



<PAGE>



and therefore suspended regular meetings of the Executive Committee in September
1994.  There were no meetings of the Executive  Committee during the fiscal year
ended June 30, 1997.

                      COMPENSATION COMMITTEE INTERLOCKS AND
                              INSIDER PARTICIPATION

     As of the date hereof, the members of the Board of Directors serving on the
Compensation  Committee  of the Board of  Directors  are Dr.  Rosina  B.  Dixon,
Chairperson,  Rolf A. Classon and Robert  LeBuhn,  all of whom are  non-employee
directors of the Company.

                    BUSINESS EXPERIENCE OF EXECUTIVE OFFICERS

     Set forth below is certain information  regarding the executive officers of
the Company who do not serve on the Board of Directors.

     John A. Caruso, 52, has served as Vice President,  Business Development and
General  Counsel of the Company  since July 1994 and as Secretary of the Company
since July 1989.  From  January  1991 to July 1994,  Mr.  Caruso  served as Vice
President,  Legal Affairs of the Company. From the time he joined the Company in
September 1987 through December 1990, Mr. Caruso served as Corporate  Counsel to
the Company.  From 1979 through 1987, Mr. Caruso was employed at Baxter Travenol
Laboratories in Deerfield, Illinois as corporate counsel.

     Kenneth  J.  Zuerblis,  38,  has served as Chief  Financial  Officer  since
January 1996 and as Vice President,  Finance since April 1994. From July 1991 to
April 1994, Mr. Zuerblis served as the Company's  Controller.  From January 1982
to July 1991,  Mr.  Zuerblis  was employed by KPMG Peat Marwick LLP. He became a
certified public accountant in 1985.

                           SUMMARY COMPENSATION TABLE

     The following  table  provides a summary of cash and non-cash  compensation
for each of the last three fiscal years ended June 30, 1997,  1996 and 1995 with
respect to Enzon's  Chief  Executive  Officer and the other  executive  officers
serving  during  the  fiscal  year ended  June 30,  1997 (the  "Named  Executive
Officers").

<TABLE>
<CAPTION>

                                                                                                     Long-Term    
                                                                                                   Compensation   
                                                Annual Compensation                                    Awards      
                                                -------------------                                  Securities           All Other
         Name and                                                              Other Annual          Underlying         Compensation
     Principal Position             Year       Salary($)        Bonus($)      Compensation($)(1)     Options(#)            ($)(2)
     ------------------             ----       ---------        --------      ------------------     -----------         ----------

<S>                                 <C>        <C>            <C>               <C>                    <C>                  <C>   
Peter G. Tombros                    1997       $307,626       $ 50,000(4)       $   --                 420,000              4,729
President and Chief                 1996        300,000           --              36,000(3)             60,000                950
 Executive Officer                  1995        300,000           --              32,000(3)            189,000              1,270
                                                                                                                         
John A. Caruso                      1997        170,000         25,000              --                  80,000                163
Vice President, Business            1996        163,651         39,100              --                  40,000                --
 Development, General Counsel       1995        122,299           --                --                  82,000                --
 and Secretary                                                                                                           
                                                                                                                         
Kenneth J. Zuerblis                 1997        148,052         40,000              --                  90,000              5,395
Vice President, Finance and         1996        132,813         24,871              --                  40,000              1,989
 Chief Financial Officer            1995        100,000           --                --                  85,000              1,500
</TABLE>



(1)  Excludes  perquisites and other personal  benefits that in the aggregate do
     not exceed 10% of the Named  Executive  Officer's  total annual  salary and
     bonus.

(2)  Consists of annual Company contributions to a 401(k) plan.

                                      - 6 -

<PAGE>



(3)  Consists  of auto and living  allowance.  As of April 5, 1997,  the Company
     ceased paying Mr. Tombros an auto and living allowance.

(4)  Mr.  Tombros has  elected to defer the payment of his bonus  earned for the
     year ended June 30, 1997.


                        OPTION GRANTS IN LAST FISCAL YEAR

     The following  table  contains  information  concerning  the grant of stock
options  under  the  Company's  Non-Qualified  Stock  Option  Plan to the  Named
Executive Officers during the fiscal year ended June 30, 1997.

<TABLE>
<CAPTION>

                                           Individual Grants
                                           -----------------

                          Number of                                                           Potential Realizable Value at Assumed
                         Securities       % of Total                                               Annual Rates of Stock Price     
                         Underlying    Options Granted                                          Appreciation for Option Term (5)   
                          Options       to Employees    Exercise or Base      Expiration      --------------------------------------
Name                     Granted (1)    in Fiscal Year     Price ($/Share)       Date            0%($)         5%($)         10%($)
- ----                    -----------    --------------   ------------------   -----------      ----------     ----------    ---------
<S>                     <C>                <C>            <C>                  <C>             <C>          <C>           <C>       
Peter G. Tombros         60,000(2)          5.82%         $  2.81              07/23/06        $  0         $ 106,126     $  268,944
                         60,000(3)          5.82%            2.56              02/11/07           0            96,693        245,038
                        300,000(4)         29.12%            2.69              04/05/07           0           505,292      1,279,501
                                                                                                                  
John A. Caruso           40,000(2)          3.88%            2.81              07/23/06           0            70,751        179,296
                         40,000(3)          3.88%            2.56              02/11/07           0            64,462        163,359
                                                                                                                  
Kenneth J. Zuerblis      50,000(2)          4.85%            2.81              07/23/06           0            88,438        224,120
                         40,000(3)          3.88%            2.56              02/11/07           0            64,462        163,359
</TABLE>

(1)  All options were granted at an exercise  price that equaled or exceeded the
     fair market value of the Common Stock on the date of grant,  as  determined
     by the last sale price as  reported  on the  NASDAQ  National  Market.  The
     options will become exercisable as to all shares immediately upon a "change
     in  control" of the  Company as defined in certain  agreements  between the
     executive  officers  and  the  Company.  See  "Employment  and  Termination
     Agreements".

(2)  These options vested and became exercisable as to 50% of the shares granted
     on July 23, 1997 with the remaining 50% of the shares  vesting and becoming
     exercisable on July 23, 1998,  provided that the Named Executive Officer is
     employed by the Company on the vesting date.

(3)  These  options  will vest and  become  exercisable  as to 50% of the shares
     granted on February  11, 1998 and the  remaining  50% on February 11, 1999,
     provided that the Named Executive Officer is employed by the Company on the
     vesting date.

(4)  Mr. Tombros' option will vest and become  exercisable on April 5, 2002. The
     vesting and  exercisability of the options granted will be accelerated,  if
     the  Company's  Common Stock  exceeds  certain  closing price levels for at
     least twenty  consecutive  trading days as reported by the NASDAQ  National
     Market.  The  options  will vest and become  exercisable  in 100,000  share
     increments if the closing price, as defined,  of the Company's Common Stock
     exceeds $4, $5 and $6 per share, respectively.

(5)  The amounts set forth in the three  columns  represent  hypothetical  gains
     that might be  achieved  by the  optionees  if the  respective  options are
     exercised at the end of their terms. These gains are based on assumed rates
     of stock price appreciation of 0%, 5% and 10% compounded  annually from the
     dates the respective  options were granted.  The 0% appreciation  column is
     included  because the options  were  granted  with  exercise  prices  which
     equaled or exceeded the market price of the underlying  Common Stock on the
     date of grant, and thus will have no value unless the Company's stock price
     increases above the exercise prices.


                                      - 7 -

<PAGE>



                   OPTION EXERCISES AND FISCAL YEAR-END VALUES

     The following  table sets forth the  information  with respect to the Named
Executive  Officers  concerning  the exercise of options  during the fiscal year
ended June 30, 1997 and unexercised options held as of June 30, 1997.

<TABLE>
<CAPTION>

                                                                   Number of Securities                   Value of Unexercised
                                                                  Underlying Unexercised                  In-the-Money Options
                                                                   Options at FY-End (#)                     at FY-End ($)(1)
                          Shares Acquired         Value          --------------------------           ---------------------------
         Name             On Exercise (#)        Realized($)     Exercisable  Unexercisable           Exercisable   Unexercisable
         ----             ---------------        -----------     -----------  -------------           -----------   -------------

<S>                            <C>                  <C>           <C>            <C>                    <C>             <C>        
Peter G. Tombros               --                   --            619,000        450,000                $28,813          --        
                                                                                                                                   
John A. Caruso                 --                   --            160,992        100,000                  6,250          --        
                                                                                                                                   
Kenneth J. Zuerblis            --                   --            130,000        110,000                  6,250          --        
</TABLE>


(1)  Based upon a market value of $2.25 as  determined by the last sale price as
     reported on the NASDAQ  National  Market on June 30, 1997.  If the exercise
     price is equal to or  greater  than  such last sale  price,  the  option is
     deemed to have no value.


                                      - 8 -


<PAGE>



                      EMPLOYMENT AND TERMINATION AGREEMENTS


     During  April  1997,  the  Company  entered  into a  three-year  employment
agreement with Mr.  Tombros  pursuant to which he receives an annual base salary
of $336,000.  In the event Mr. Tombros' employment is terminated for any reason,
except if such  employment is terminated  (i)  voluntarily by Mr. Tombros (other
than in  response  to the  Company's  prior  material  breach of the  employment
agreement),  (ii) by the  Company  "for  cause" (as  defined  in the  employment
agreement) or (iii) as a result of Mr. Tombros' death or disability, Mr. Tombros
will be entitled to receive his base salary for one year after such termination.
In the  event  Mr.  Tombros'  employment  is  terminated  due to  his  death  or
disability  his base  salary  will be paid  for six  months  subsequent  to such
termination.  Pursuant to his  employment  agreement,  Mr. Tombros was granted a
ten-year option under the Company's  Non-Qualified Stock Option Plan to purchase
300,000  shares of the Company's  Common Stock at a per share  exercise price of
$2.69, the fair market value of the Company's Common Stock on the date of grant.
The option vests and becomes  exercisable  on April 5, 2002 provided Mr. Tombros
does not  voluntarily  terminate  his  employment  with the  Company  (except in
response to the Company's  prior material  breach of the  employment  agreement)
prior to the  relevant  vesting  date.  The  vesting and  exercisability  of the
options  granted will be  accelerated  if the  Company's  Common  Stock  exceeds
certain  closing  price levels for at least twenty  consecutive  trading days as
reported  by the  NASDAQ  National  Market.  The  option  will  vest and  become
exercisable  in 100,000  share  increments  if the  closing  stock  price of the
Company's  closing  stock  price,  as  defined,  exceed $4, $5 and $6 per share,
respectively.  Mr. Tombros'  employment  agreement also requires him to maintain
the confidentiality of Company information and assign inventions to the Company.
Mr.  Tombros is precluded from competing with the Company during the term of his
employment agreement and for two years after his employment is terminated if his
employment is terminated by the Company for cause or by Mr. Tombros  voluntarily
(except in response to the Company's  prior  material  breach of the  employment
agreement).

     The  Company  has  agreements  with each of its  executive  officers  which
provide for payment to each executive officer of three years of compensation and
benefits  (as defined in such  agreements)  following a change in control of the
Company  (as  defined in such  agreements),  including  the  provision  for such
payment in the event such  executive  officer's  employment  with the Company is
terminated under certain circumstances  following such change in control. Upon a
change in control of the Company,  all options held by such  executive  officers
shall vest  immediately,  notwithstanding  any vesting  provisions in the option
certificates or any plan covering such options.  The term of these agreements is
for three  years.  Prior to a change in control of the Company,  the  agreements
automatically  renew on each  successive  anniversary  for an  additional  three
years,  unless the Company gives the  executive  officer 60 days notice prior to
the anniversary date that it does not plan to renew such contracts.

                                      - 9 -


<PAGE>



         REPORT OF THE COMPENSATION COMMITTEE OF THE BOARD OF DIRECTORS

     The  Compensation  Committee  of the Board of  Directors  consists of three
non-employee  directors and determines all  compensation  paid or awarded to the
Company's  executive  officers,  including the Named  Executive  Officers in the
Summary Compensation Table. As with many other biotechnology companies,  Enzon's
current level of development  and the highly  volatile  nature of  biotechnology
stocks  in  general  makes  executive  compensation  which is based on sales and
earnings goals or stock performance  impracticable.  The Compensation  Committee
believes  that  an  important   factor  in  Enzon's  success  is  the  continued
development and maintenance of a culture focused on  team-oriented  performance.
In this context, compensation has been based on the accomplishment of a blend of
mutually shared and individual  goals. The  Compensation  Committee has reviewed
the executive  compensation  of other  biotechnology  companies with  comparable
levels of  stockholders'  equity and  development and has designed the Company's
total  executive  compensation  to  be  targeted  at  the  median  of  executive
compensation  levels  of these  companies.  The  compensation  of the  Company's
executive  officers consist of three principal  components:  (i) base salary and
benefits,  (ii) a bonus  based on  individual  contributions  evaluated  against
annual goals and (iii) long-term incentives in the form of stock option grants.

     During April 1997, the Compensation  Committee  renewed the Company's Chief
Executive  Officer,  Peter G. Tombros' contract for a period of three years. The
contract  increased Mr. Tombros' salary to $336,000 from $300,000.  The contract
also  eliminated  certain living  allowances that were paid to Mr. Tombros under
the previous contract. The living allowance totaled approximately $36,000 during
the fiscal year ended June 30, 1996. Prior to this increase, Mr. Tombros' salary
was not  increased  during  the  previous  three  years,  at the  request of Mr.
Tombros. The Compensation  Committee also awarded Mr. Tombros a bonus for fiscal
year end June 30,  1997 of  approximately  $50,000.  The bonus was based on many
factors  including the  strengthening  of the Company's  financial  position and
improving its strategic  focus.  Mr. Tombros has elected to defer the payment of
his bonus until a future date  determined  by him. The annual salary of $336,000
provided in Mr.  Tombros' new  employment  agreement  and the bonus awarded were
based on Mr.  Tombros'  extensive  experience  as a senior  executive of a major
multinational  pharmaceutical  firm and the compensation paid to chief executive
officers with similar  credentials at comparable biotech companies.  Pursuant to
Mr. Tombros' new employment agreement, the Compensation Committee also granted a
ten year option to purchase  300,000 shares of Common Stock at a per share price
of $2.69,  the fair market  value of the  Company's  Common Stock on the date of
grant.  The option vests and becomes  exercisable  on April 5, 2002.  The option
provides for an  acceleration  of vesting and  exercisability  if the  Company's
Common  Stock  exceeds   certain  closing  price  levels  for  at  least  twenty
consecutive  trading days as reported by the NASDAQ National Market.  The option
vests and becomes  exercisable in 100,000 share  increments if the closing price
of the  Company's  Common  Stock,  as defined,  exceeds $4, $5 and $6 per share,
respectively.

     During the fiscal  year ended June 30,  1997,  the  Compensation  Committee
awarded cash bonuses to the Company's other executive officers,  Messrs.  Caruso
and  Zuerblis.  The  bonuses  were  based  on the  executives'  contribution  to
improvement of the Company's financial  position.  The Company also adjusted the
salary level of Mr.  Zuerblis.  The salary  adjustment  and bonus  payments were
based on a detailed compensation study of executives with similar credentials at
comparable biotechnology companies.

     In addition to the option granted under Mr. Tombros'  employment  contract,
the Compensation Committee granted,  during the fiscal year ended June 30, 1997,
options to purchase an  aggregate  of 290,000  shares of Common Stock to Messrs.
Tombros,  Caruso and  Zuerblis.  These  options  were granted for the purpose of
encouraging these executive officers to remain with the Company and to provide a
long-term performance incentive to such officers.  The options were granted with
exercise  prices that equaled or exceeded the fair market value of the Company's
Common Stock on the date of grant. The options  generally  require the executive
officers to remain with the Company for two years in order for the options to be
fully exercisable. 

                                                THE COMPENSATION COMMITTEE

                                                Dr. Rosina B. Dixon, Chairperson
                                                Rolf A. Classon
                                                Robert LeBuhn


                                     - 10 -

<PAGE>



                      STOCKHOLDER RETURN PERFORMANCE GRAPH


     The graph below summarizes the total cumulative  return  experienced by the
Company's stockholders from June 30, 1992 through June 30, 1997, compared to the
NASDAQ  Stock  Market  Index  and  a  Peer  Group  index   consisting  of:  Isis
Pharmaceuticals,  Inc., Repligen Corp.,  Celgene Corp.,  Gensia  Pharmaceuticals
Inc.,  Collagen Corp.,  Liposome Inc.,  Cytel Corp.,  Cytogen Corp. and Cephalon
Inc. (the "Peer Group"). The Company and the companies comprising the Peer Group
are biotechnology companies which are all traded on the NASDAQ Stock Market. The
Peer Group used for the stockholder  return  performance  graph does not include
Synergen Inc.,  Cambridge  Biotech  Corporation,  DNA Plant  Technology Corp. or
Calgene,  Inc.  which were  included in the Peer Group in prior years.  Synergen
Inc.,  DNA Plant  Technology  and Calgene Inc.  were  acquired and are no longer
publicly traded. Cambridge Biotech Corporation is no longer traded on the NASDAQ
Stock Market. The changes for the periods shown in the graph and table below are
based on the assumption that $100 had been invested in Enzon,  Inc. Common Stock
and in each index below on June 30, 1992.



              COMPARISON OF FIVE YEAR CUMULATIVE TOTAL RETURN AMONG
         ENZON, INC., THE NASDAQ STOCK MARKET-US INDEX AND A PEER GROUP




                                           Fiscal year ending June 30,
                                ------------------------------------------------
                                1992     1993     1994     1995     1996    1997
                                ----     ----     ----     ----     ----    ----

Enzon, Inc.                     100       71       40       35       51       33
Peer Group                      100       75       44       53       72       45
NASDAQ  Stock
  Market-US                     100      126      127      169      218      265



                                     - 11 -

<PAGE>



                          SECURITY OWNERSHIP OF CERTAIN
                        BENEFICIAL OWNERS AND MANAGEMENT

     The  following  table  sets  forth  certain  information  concerning  stock
ownership of all persons known by the Company to own  beneficially 5% or more of
the  outstanding  shares of the Company's  voting  stock,  each  Director,  each
Executive  Officer  named in the Summary  Compensation  Table and all  Executive
Officers  and  Directors  of the  Company  as a group as of  October  23,  1997:


                                                                   Percentage of
Directors, Officers or                             Number of        Voting Stock
5% Stockholders(1)                                 Shares(2)      Outstanding(3)
- ---------------------                           -------------    --------------

Peter G. Tombros                                  806,300(4)           2.5%
Randy H. Thurman                                  218,228(5)            *
Rolf A. Classon                                     3,630               *
Dr. Rosina B. Dixon                                79,892(6)            *
Robert LeBuhn                                      85,010(7)            *
A.M. "Don" MacKinnon                              139,822(8)            *
John A. Caruso                                    230,292(9)            *
Kenneth J. Zuerblis                               176,600(10)           *
Clearwater Fund IV Ltd.                         2,832,831(11)          9.0%
  P.O. Box 662
  Tortola, British Virgin Islands
State of Wisconsin                              2,521,000(12)          8.1%
  Investment Board
  P.O. Box 7842
  Madison, Wisconsin 53707
All Executive Officers and Directors            1,739,780(13)          5.3%
 as a group (eight persons)

- ------------------
* Less than one percent.

(1)  The address of all current Executive Officers and Directors listed above is
     in the care of the Company.

(2)  All shares  listed are Common  Stock.  Except as discussed  below,  none of
     these  shares are  subject to rights to acquire  beneficial  ownership,  as
     specified in Rule 13d-3(d)(1) under the Securities Exchange Act of 1934, as
     amended,  and the beneficial  owner has sole voting and  investment  power,
     subject to community property laws where applicable.

(3)  Gives effect to  30,922,744  shares of Common  Stock and 108,000  shares of
     Series A Preferred  Stock which were issued and  outstanding  as of October
     23,  1997.  Generally,  the Series A Preferred  Stock and Common Stock will
     vote as one class of stock.  Each  share of Common  Stock and each share of
     Series A Preferred  Stock is entitled to one vote. The percentage of voting
     stock  outstanding  for each  stockholder is calculated by dividing (i) the
     number of shares deemed to be beneficially  held by such  stockholder as of
     October  23,  1997 by (ii) the sum of (A) the  number  of  shares of Common
     Stock  outstanding  as of October 23, 1997 plus (B) the number of shares of
     Series A Preferred  Stock  outstanding  as of October 23, 1997 plus (C) the
     number of shares issuable upon exercise of options or warrants held by such
     stockholder  which were  exercisable  as of October  23, 1997 or which will
     become exercisable within 60 days after October 23, 1997.

(4)  Includes  779,000  shares  subject to options which were  exercisable as of
     October  23,  1997 or which will  become  exercisable  within 60 days after
     October 23, 1997.


                                     - 12 -

<PAGE>



(5)  Consists of 195,000 shares subject to options which were  exercisable as of
     October  23,  1997 or which will  become  exercisable  within 60 days after
     October 23, 1997.

(6)  Includes  56,664  shares  subject to options which were  exercisable  as of
     October  23,  1997 or which will  become  exercisable  within 60 days after
     October 23, 1997.

(7)  Includes  56,664  shares  subject to options which were  exercisable  as of
     October  23,  1997 or which will  become  exercisable  within 60 days after
     October 23, 1997.

(8)  Includes  112,000  shares  subject to options which were  exercisable as of
     October  23,  1997 or which will  become  exercisable  within 60 days after
     October 23, 1997 and 11,800 shares  beneficially  owned by Mr.  MacKinnon's
     wife. Mr. MacKinnon disclaims  beneficial  ownership as to the shares owned
     by his wife.

(9)  Consists of 229,992 shares subject to options which were  exercisable as of
     October  23,  1997 or which will  become  exercisable  within 60 days after
     October 23, 1997.

(10) Includes  175,000  shares  subject to options which were  exercisable as of
     October  23,  1997 or which will  become  exercisable  within 60 days after
     October 23, 1997 and 600 shares owned by Mr. Zuerblis' IRA.

(11) Includes  warrants to purchase 273,723 shares of the Company's Common Stock
     at $4.11 per share and  warrants to purchase  200,000  shares at $5.625 per
     share.  The  information  concerning the Stock  ownership of the Clearwater
     Fund IV Ltd. was obtained  from a schedule 13D filed with the Securites and
     Exchange Commission dated February 28, 1997.

(12) The  information  concerning the stock  ownership of the State of Wisconsin
     Investment  Board was  obtained  from a schedule  13F filed by the State of
     Wisconsin  Investment  Board with the  Securities  and Exchange  Commission
     dated February 10, 1997.

(13) Includes  all  shares  owned  beneficially  by the  directors  and  current
     executive officers named in the Summary Compensation table.


                                     - 13 -

<PAGE>



                          PROPOSAL NO. 2 - APPROVAL OF
                 PROPOSED AMENDMENT TO THE COMPANY'S CERTIFICATE
              OF INCORPORATION TO INCREASE AUTHORIZED COMMON STOCK

     At present the Company is authorized to issue  40,000,000  shares of Common
Stock,  $.01 par value per share and 3,000,000 shares of Preferred  Stock,  $.01
par value per share.  As of October  23,  1997,  there  were  108,000  shares of
Preferred Stock designated as Series A Preferred Stock  outstanding.  Also as of
that  date,  there  were  30,922,744  shares of  Common  Stock  outstanding  and
4,292,967 shares reserved for issuance pursuant to various  outstanding  options
to purchase Common Stock, 1,458,088 shares reserved for additional options which
may be granted  under the  Non-Qualified  Stock  Option Plan,  1,038,686  shares
reserved  pursuant to  outstanding  warrants to purchase  Common Stock,  245,455
shares  reserved for issuance upon  conversion  of the Series A Preferred  Stock
outstanding. Thus, as of October 23, 1997, 2,042,060 shares of Common Stock were
available for issuance.

     The Board of  Directors  believes  that it is in the best  interest  of the
Company  to  increase  the  authorized  number of shares  of Common  Stock  from
40,000,000 to 60,000,000.  The Company may need to issue additional Common Stock
to consumate strategic acquisitions, technology or product licensing agreements,
implement  additional  management  or  employee  incentive  programs  or  obtain
additional financing. On October 7, 1997, the Board of Directors voted to submit
to a vote of  stockholders  an amendment  to the  Certificate  of  Incorporation
increasing the authorized  Common Stock.  The Company has no present  agreement,
commitment, plan or intent to issue any of the additional shares provided for in
this Proposal.

     If this Proposal is approved the additional authorized Common Stock as well
as the  currently  authorized  but unissued  Common Stock would be available for
issuance in the future for such  corporate  purposes  as the Board of  Directors
deems  advisable from time to time without  further action by the  stockholders,
unless such action is required by applicable law or by the rules of NASDAQ or of
any stock exchange upon which the Company's shares may then be listed.

     The  Company's  Common  Stock is  currently  quoted on the NASDAQ  National
Market.  One of the  non-quantitative  maintenance  criteria for National Market
System securities requires stockholder approval for the establishment of certain
plans or arrangements by the Company or the issuance of designated securities by
the Company.  This criterion  provides that, for so long as the Company's Common
Stock is included in NASDAQ,  stockholder  approval will be required for (i) the
establishment  of a stock  option or  purchase  plan or other  arrangement  made
pursuant to which stock may be  acquired  by officers or  directors,  except for
warrants  or rights  issued  generally  to  security  holders of the  Company or
broadly based plans or arrangements  including other  employees,  and certain de
minimus  issuances  thereunder  or  issuances  to  induce  individuals  to enter
employment  contracts;  (ii) the issuance of  securities  which will result in a
change of control of the issuer;  (iii) the issuance of securities in connection
with the  acquisition  of the  stock or  assets of  another  company  (a) if any
director,  officer or substantial stockholder of the Company has a 5% or greater
interest (or such persons collectively have a 10% or greater interest), directly
or indirectly,  in the company or assets to be acquired or in the  consideration
to be paid in the transaction or series of related  transactions and the present
or  potential  issuance  of  Common  Stock  or  securities  convertible  into or
exercisable for Common Stock,  could result in an increase in outstanding Common
Shares or voting  power of 5% or more,  or (b) where the  present  or  potential
issuance of Common Stock,  or securities  convertible  into or  exercisable  for
Common Stock, other than a public offering for cash, if the Common Stock has, or
will have upon issuance, voting power equal to or in excess of 20% of the voting
power outstanding before the issuance of stock or securities convertible into or
exercisable  for Common  Stock,  or the  number of shares of Common  Stock to be
issued  is or will be equal to or in  excess  of 20% of the  number of shares of
Common Stock outstanding before the issuance of stock or securities;  or (iv) in
connection with a transaction,  other than a public offering,  involving (x) the
issuance of Common Stock,  or securities  convertible  into or  exercisable  for
Common Stock,  at a price less than the greater of book or market  value,  which
together with sales by officers,  directors or substantial  stockholders  of the
Company  equals  20% or more of the  Common  Stock or 20% or more of the  voting
power outstanding before the issuance,or (y) the sale or issuance by the Company
of Common Stock (or securities  convertible into or exercisable for Common Stock
equal  to 20% or more of the  Common  Stock or 20% or more of the  voting  power
outstanding  before  the  issuance  for less than the  greater of book or market
value of the stock.


                                     - 14 -

<PAGE>



     The  additional  authorized  shares of  Common  Stock  resulting  from this
Proposal  would  be the  same  as the  existing  shares  of  Common  Stock.  All
outstanding Common Stock would continue to have one vote per share. Stockholders
of the Company do not presently have preemptive rights nor will they as a result
of the Proposal.

     Authorized  shares of Common  Stock in excess of those  shares  outstanding
(including,  if  authorized,  the  additional  Common Stock provided for in this
Proposal) will remain available for general corporate purposes, may be privately
placed  and  can be used  to  make a  change  in  control  of the  Company  more
difficult.  Under  certain  circumstances,  the Board of Directors  could create
impediments to, or frustrate persons seeking to effect a takeover or transfer in
control  of the  Company  by  causing  such  shares  to be issued to a holder or
holders who might side with the Board of  Directors  in opposing a takeover  bid
that the  Board of  Directors  determines  is not in the best  interests  of the
Company and its stockholders, but in which unaffiliated stockholders may wish to
participate.   In  these  circumstances  the  Board  of  Directors  could  issue
authorized  shares  of Common  Stock to a holder or  holders  which  when  voted
together  with the  shares  held by members  of the Board of  Directors  and the
executive officers and their families could prevent the 66-2/3% stockholder vote
required  by  the  Company's  Certificate  of  Incorporation  to  eliminate  the
Company's  classified  or  "staggered"  Board  of  Directors.  Furthermore,  the
existence of such shares might have the effect of discouraging  any attempt by a
person,  through the  acquisition  of a  substantial  number of shares of Common
Stock,  to acquire  control of the  Company,  since the  issuance of such shares
could dilute the Company's  book value per share and the Common Stock  ownership
of such person.  One of the effects of the  Proposal,  if approved,  might be to
render  the  accomplishment  of a  tender  offer  more  difficult.  This  may be
beneficial  to  management  in a hostile  tender  offer,  thus having an adverse
impact on stockholders who may want to participate in such tender offer.

     It should be noted that subject to the limitations  discussed above, all of
the types of Board action described in the preceding  paragraph can currently be
taken and that the power of the Board of Directors  to take such  actions  would
not be enhanced by this  Proposal,  although  this Proposal  would  increase the
number of shares of Common Stock that are subject to such action.

     This Proposal,  the Company's  authorized but unissued Preferred Stock, the
Company's  classified  Board of Directors and change in control  agreements  the
Company  has  with  its  executive  officers  may  generally  be  classified  as
"anti-takeover"  measures  and may each,  or in  conjunction  with  each  other,
discourage  attempted  takeovers  of the Company  which are not  approved by the
Board of Directors. The Company does not believe that any other provision of its
current  Certificate of  Incorporation or By-Laws are intended or would have the
effect of  discouraging  or making more difficult the  acquisition of control of
the Company.

     If the Proposal is approved and the Amendment becomes effective,  the first
sentence of Article 4 of the Company's Certificate of Incorporation,  which sets
forth the Company's presently  authorized capital stock, will be amended to read
in its entirety as follows:

     "4. The total number of shares of capital stock which the Corporation shall
have authority to issue is 63,000,000  shares,  of which 60,000,000 shares shall
be Common  Stock,  par value  $.01 per  share,  and  3,000,000  shares  shall be
Preferred Stock, par value $.01 per share."

     The Board of  Directors  recommends  a vote FOR approval of an amendment to
the Company's  Certificate of Incorporation to increase the authorized shares of
Common Stock from 40,000,000 to 60,000,000 (Proposal No. 2 on the proxy card).


                                     - 15 -

<PAGE>



                     PROPOSAL NO. 3 - APPROVAL OF AMENDMENT
                     TO THE NON-QUALIFIED STOCK OPTION PLAN

     In  November   1987,   the  Company's   Board  of  Directors   adopted  the
Non-Qualified  Stock  Option Plan (the "Plan") in order to enable the Company to
attract and retain qualified employees,  directors and independent  consultants.
Subject  to  stockholder  approval,  the  Board of  Directors  has  approved  an
amendment to the Plan to reflect  changes made to the rules under  Section 16(b)
of the Securities Exchange Act 1934 (the "Exchange Act").

     The following summary  description of the Plan is qualified in its entirety
by the full text of the Plan which may be obtained by the Company's stockholders
upon request to the Secretary of the Company.

     The last sale price of a share of the Company's Common Stock as reported by
the NASDAQ National Market on October 23, 1997 was $6.63.

Basic Terms

     Under the Plan,  directors,  officers  and  employees  of the  Company  and
independent  consultants  to the Company  have been,  and will be,  eligible for
grants of options to  purchase  shares of Common  Stock.  To date,  all  options
granted  under the Plan  have been  awarded  at the  discretion  of the Board of
Directors or a committee  thereof or pursuant to the formulas  described  below.
Currently,  the Compensation  Committee of the Board of Directors determines who
will receive  options under the Plan, the number of shares of Common Stock which
will be issuable  upon  exercise of options which are granted under the Plan and
the terms of the options  granted under the Plan to the extent the terms are not
otherwise  set  forth in the  Plan.  No  option  granted  under  the Plan may be
transferred  by the optionee,  otherwise than by will or the laws of descent and
distribution and, generally,  during the optionee's lifetime,  the option may be
exercised  only by the  optionee.  The exercise  price of the options must be at
least equal to the fair market  value of the  underlying  Common Stock as of the
date of grant.  Either the  Compensation  Committee of the Board of Directors or
the Board of Directors may, in its discretion, provide that an option may not be
exercised in whole or in part for any  specified  period or periods of time.  No
option  may be  exercised  prior to six  months  from  the date of grant  except
immediately  prior to the  dissolution or liquidation of the Company or a merger
or consolidation  where the Company is not the surviving  corporation,  in which
case all outstanding options become immediately  exercisable.  Options expire no
later than the tenth anniversary of the date of grant.

Automatic Awards To Independent Directors

     The Plan provides that Independent Directors receive option grants pursuant
to a formula (the  "Formula").  The Formula  provides that on each of January 2,
1994,  January  2,  1997,  January  2, 2000 and  January  2,  2003,  each of the
Company's Independent Directors will automatically receive an option to purchase
60,000  shares  of  Common  Stock  (the  "Regular  Grant").  On the date of each
Independent  Director's initial election to the board, pursuant to a vote of the
Company's  stockholders or the board, such  newly-elected  Independent  Director
will automatically receive (i) an option to purchase such Independent Director's
pro rata share of the  Regular  Grant,  which  will  equal the  product of 1,666
multiplied  by the number of whole months  remaining in the relevant  three year
period until the next Regular Grant (the "Pro Rata  Grant");  and (ii) an option
to purchase 10,000 shares of Common Stock (the "Initial Election  Grant").  Each
option granted to an Independent  Director pursuant to the Formula will vest and
become exercisable as follows: those options granted pursuant to a Regular Grant
will vest and become  exercisable as to 20,000 shares one year after the date of
grant;  as to 20,000  shares  two years  after the date of grant;  and as to the
remaining  20,000  shares  three  years after the date of grant.  Those  options
granted pursuant to a Pro Rata Grant will vest and become exercisable as to that
number of shares equal to the product of 1,666 multiplied by the number of whole
months remaining in the first calendar year in which the Independent Director is
elected  initially to the board on the January 1st  following  such  Independent
Director's  initial  election to the board;  and as to any  remaining  shares in
accordance  with the schedule for options  granted  pursuant to a Regular Grant.
Those options granted pursuant to an Initial Election Grant will vest and become
exercisable as to 5,000 shares one year after the date of grant; and as to 5,000
shares two years after the date of grant.


                                     - 16 -

<PAGE>



     An option granted to an Independent  Director  pursuant to the Formula will
not  become  exercisable  as to the  relevant  shares  unless  such  Independent
Director has served continuously on the board during the year preceding the date
on which such options are scheduled to vest and become exercisable,  or from the
date such  Independent  Director  joined  the  board  until the end of such year
should  such  Independent  Director  have  joined  the board  during  such year;
provided,  however,  that if an  Independent  Director  does  not  fulfill  such
continuous  service  requirement  due to such  Independent  Director's  death or
disability,  all options granted under the Formula and held by such  Independent
Director  shall   nonetheless  vest  and  become   exercisable  as  though  such
Independent  Director  fulfilled the continuous service  requirement.  An option
granted  to  an  Independent  Director  pursuant  to  the  Formula  will  remain
exercisable for a period of ten years from the date of grant.

Administration

     The Plan is to be  administered  by  either  the  Board of  Directors  or a
committee  of at  least  two  directors  appointed  by the  board.  The  Plan is
currently administered by the Compensation Committee.

Amendments and Termination

     Currently,  no options may be granted  under the Plan beyond  November  21,
2007. The Compensation Committee or the Board of Directors may terminate, amend,
or revise the Plan with respect to any shares as to which  options have not been
granted, but may not alter any previously granted options without the optionee's
consent. Termination of the Plan will not affect previously granted options. See
"Proposed  Amendments to the Plan" for a discussion of the current  restrictions
on the ability of the Compensation  Committee or the Board of Directors to amend
the Plan.

Capital Adjustments

     The aggregate  number of shares of Common Stock available for options,  the
shares  subject  to  any  option,   and  the  price  per  share,   will  all  be
proportionately  adjusted  for any  increase or decrease in the number of issued
shares of Common Stock  resulting  from (1) a subdivision  or  consolidation  of
shares or any other capital  adjustment,  (2) the payment of a stock dividend on
the  Company's  Common Stock,  or (3) other  increase or decrease in such shares
effected without receipt of  consideration by the Company.  If the Company shall
be the  surviving  corporation  in  any  merger  or  consolidation,  any  option
outstanding under the Plan shall pertain, apply, and relate to the securities to
which a holder of the  number of shares of Common  Stock  subject  to the option
would have been entitled after the merger or consolidation.  Upon dissolution or
liquidation  of the  Company,  or upon a merger  or  consolidation  in which the
Company is not the surviving corporation, all options outstanding under the Plan
shall  terminate;  except that each optionee  shall have the right,  immediately
prior to such dissolution or liquidation,  or such merger or  consolidation,  to
exercise the options that such optionee holds in whole or in part.

Tax Consequences

     An  optionee  will not  recognize  taxable  income for  Federal  income tax
purposes upon the receipt of an option under the Plan,  and the Company will not
be  entitled  to a deduction  upon the grant of an option.  Upon  exercise of an
option,  the optionee will recognize  ordinary income equal to the excess of the
fair  market  value on the date of exercise of the Common  Stock  received  upon
exercise  over the  exercise  price for such  Common  Stock.  However,  any such
optionee  who is subject to the  trading  restrictions  of Section  16(b) of the
Exchange Act would,  unless the optionee elected to recognize ordinary income on
the  date of  exercise,  recognize  ordinary  income  on the date  such  trading
restrictions  terminate (the "Deferred  Date").  The amount of such income would
equal the excess of the fair  market  value on the  Deferred  Date of the Common
Stock  received  upon  exercise of the option over the  exercise  price for such
Common Stock, and the holding period for long-term  capital gain treatment would
not begin until the Deferred  Date.  The Company will be entitled to a deduction
equal to the amount of ordinary  income  recognized  by any optionee at the same
time that such optionee recognized such income.


                                     - 17 -

<PAGE>



Eligible Participants

     As of October 23, 1997,  there were  approximately  94 persons  eligible to
participate in the Plan. Of these eligible participants,  six are members of the
Board of Directors (five of whom are Independent Directors), five are members of
the Company's  Scientific Advisory Board, two are executive officers who are not
board  members  and the  remainder  are  employees  of the  Company  who are not
executive officers.

Proposed Amendments to the Plan

     Currently,  the Plan  contains  certain  provisions  which were designed to
comply with the requirements of Rule 16b-3 prior to the amendments to Rule 16b-3
adopted by the SEC in May 1996 ("Old Rule  16b-3").  The  amendments to the Plan
proposed  herein are  designed to reflect the current  provisions  of Rule 16b-3
("Current Rule 16b-3").

     The Plan currently  provides that the Board may not grant options under the
Plan or take certain  other  actions  with  respect to such options  unless each
member of the Board is a "disinterested  person", as such term is defined in Old
Rule 16b-3.  The Plan also  provides  that the Plan may be  administered  by the
Compensation  Committee of the Board. Under Old Rule 16b-3 all of the members of
the  Compensation  Committee  had to be  "disinterested  persons".  The  Plan as
amended would provide that the Plan is to be administered by either the Board or
the  Compensation  Committee  and that at least two members of the  Compensation
Committee  must be  "nonemployee  directors," as such term is defined in Current
Rule 16b-3. The concept of a "disinterested  person" will be eliminated from the
Plan.

     The  Plan  currently  provides  that no  amendment  may be made to the Plan
without stockholder  approval where such amendment would materially (i) increase
the total number of shares  which may be issued  under the Plan;  (ii) alter the
class of persons  eligible to  participate  in the Plan;  or (iii)  increase the
benefits under the Plan.  These provisions were consistent with the requirements
of Old Rule  16b-3.  The Plan as amended  would  provide  that the Plan could be
amended by the Board without  stockholder  approval unless stockholder  approval
was required by applicable  law or the rules of NASDAQ or any stock  exchange on
which the Company's shares are then traded.

     For information concerning options granted under the Plan to directors, the
Chief  Executive  Officer  and the  Named  Executive  Officers  see  "Directors'
Compensation  - Directors'  Stock  Options,"  "Summary  Compensation  Table" and
"Option Grants In Last Fiscal Year."


     The Board of Directors  recommends a vote FOR approval of the  amendment to
the Non-Qualified Stock Option Plan (Proposal No. 3 on the Proxy Card).

                    PROPOSAL NO. 4 - RATIFICATION OF AUDITORS

     On October 7, 1997, the Audit Committee of the Board of Directors, pursuant
to authority  granted by the Board of Directors,  approved the retention of KPMG
Peat Marwick LLP ("KPMG"),  independent  certified public accountants,  to audit
the consolidated  financial statements of the Company for the fiscal year ending
June 30, 1998. KPMG served as auditor of the consolidated  financial  statements
of the Company for the fiscal years ended June 30, 1997, June 30, 1996, and June
30,  1995.  Representatives  of KPMG are  expected  to be  present at the Annual
Meeting and will have the opportunity to make a statement  should they desire to
do so. Such  representatives  are also  expected to be  available  to respond to
questions.

     The Board of Directors  recommends a vote FOR ratification of the selection
of KPMG Peat Marwick LLP, independent certified public accountants, to audit the
consolidated financial statements of the Company for the fiscal year ending June
30, 1998 (Proposal No. 4 on the Proxy Card).


                                     - 18 -

<PAGE>



                          ANNUAL REPORT TO STOCKHOLDERS

     The Company's  Annual Report to Stockholders for the fiscal year ended June
30, 1997 accompanies this Proxy Statement.

                             STOCKHOLDERS' PROPOSALS

     It is  anticipated  that  the  Company's  fiscal  1998  Annual  Meeting  of
Stockholders will be held on or about December 1, 1998.  Stockholders who intend
to present  proposals at such Annual Meeting of  Stockholders  must submit their
proposals to the Secretary of the Company on or before July 3, 1998.

                                     GENERAL

     The cost of soliciting proxies will be borne by the Company. In addition to
mailing,  proxies  may  be  solicited  by  personal  interview,   telephone  and
telegraph,  and by  directors,  officers  and regular  employees of the Company,
without special compensation  therefor.  The Company expects to reimburse banks,
brokers  and  other  persons  for their  reasonable  out-of-pocket  expenses  in
handling proxy materials for beneficial owners of the Company's Common Stock.

     Unless  contrary  instructions  are indicated on the proxy card, all Common
Shares  or Series A  Preferred  Shares  represented  by valid  proxies  received
pursuant to this  solicitation  (and not revoked  before they are voted) will be
voted FOR the  election  of the  nominees  for  directors  named  herein and FOR
Proposal No. 2, Proposal No. 3 and Proposal No. 4.

     Any proxy given pursuant to this  solicitation may be revoked by the person
giving it at any time before it is voted.  Proxies may be revoked by filing with
the Secretary of the Company  written notice of revocation  bearing a later date
than the proxy, by duly executing a subsequent proxy relating to the same Common
Shares or Series A  Preferred  Shares or by  attending  the Annual  Meeting  and
voting in person.  Attendance  at the Annual  Meeting  will not in and of itself
constitute  revocation of a proxy unless the stockholder votes his or her Common
Shares or Series A Preferred Shares in person at the Annual Meeting.  Any notice
revoking a proxy should be sent to the Secretary of the Company, John A. Caruso,
at Enzon, Inc., 20 Kingsbridge Road, Piscataway, New Jersey 08854.

     The Board of Directors knows of no business other than that set forth above
to be  transacted at the meeting,  but if other matters  requiring a vote of the
stockholders  arise,  the  persons  designated  as proxies  will vote the Common
Shares or Series A Preferred  Shares  represented  by the proxies in  accordance
with their  judgment on such  matters.  If a  stockholder  specifies a different
choice on the proxy,  his or her Common Shares or Series A Preferred Shares will
be voted in accordance with the specification so made.

     Please complete,  sign and date the enclosed proxy card, which is revocable
as described herein, and mail it promptly in the enclosed postage-paid envelope.


     IT IS IMPORTANT THAT PROXIES BE RETURNED PROMPTLY.  WE URGE YOU TO FILL IN,
SIGN AND RETURN THE  ACCOMPANYING  PROXY CARD, NO MATTER HOW LARGE OR SMALL YOUR
HOLDINGS MAY BE.

                                             By order of the Board of Directors,


                                             /S/ John A. Caruso
                                                 --------------------------
                                                 John A. Caruso, Secretary

Piscataway, New Jersey
October 31, 1997

                                     - 19 -

<PAGE>



Proxy Card



                                   ENZON, INC.

                 Annual Meeting of Stockholders December 2, 1997
           This Proxy Is Solicited on Behalf of the Board of Directors

     Peter G. Tombros and John A. Caruso and each of them, as proxies, with full
power of substitution in each of them, are hereby authorized to represent and to
vote, as  designated  below and on the reverse side, on all proposals and in the
discretion  of the proxies on such other matters as may properly come before the
annual  meeting of  stockholders  of Enzon,  Inc. (the  "Company") to be held on
December  2,  1997 or any  adjournment(s),  postponement(s),  or other  delay(s)
thereof (the "Annual Meeting"),  all shares of stock of the Company to which the
undersigned is entitled to vote at the Annual Meeting.

     UNLESS OTHERWISE DIRECTED, THIS PROXY WILL BE VOTED "FOR" PROPOSALS 1, 2, 3
and 4 AND WILL BE VOTED IN THE  DISCRETION  OF THE PROXIES ON SUCH OTHER MATTERS
AS MAY  PROPERLY  COME  BEFORE  THE  ANNUAL  MEETING.  THE  BOARD  OF  DIRECTORS
RECOMMENDS THAT STOCKHOLDERS VOTE "FOR" PROPOSALS 1, 2, 3 and 4.

(1)  Election of the  following  nominees as Class II Directors to serve in such
     capacities until their successors are duly elected and qualified:


               RANDY H. THURMAN                       A.M. "DON" MACKINNON


(Authority to vote for any nominee(s) may be withheld by lining through the
name(s) of any such nominee(s).)

                 / / FOR all nominees     / / WITHHOLD authority for all

(2)  Proposal to amend the Company's  Certificate of  Incorporation  to increase
     the number of authorized  shares from forty million  (40,000,000)  to sixty
     million (60,000,000).

               / / FOR                / / AGAINST              / / ABSTAIN

(3)  Proposal  to approve an  amendment  to the  Company's  Non-Qualified  Stock
     Option Plan, as set forth in the Company's  Proxy  Statement  dated October
     31, 1997.

              / / FOR                / / AGAINST               / / ABSTAIN



                                     - 20 -

<PAGE>


(4)  Ratification  of the  selection  of KPMG  Peat  Marwick  LLP to  audit  the
     consolidated financial statements of the Company for the fiscal year ending
     June 30, 1998.

               / / FOR                / / AGAINST               / / ABSTAIN

/ / Please check this box if you expect to attend the Annual Meeting in person.

                    (Please sign  exactly as name appears to the left,  date and
                    return.  If shares are held by joint  tenants,  both  should
                    sign.  When  signing as attorney,  executor,  administrator,
                    trustees or guardian,  please give full title as such.  If a
                    corporation, please sign in full corporate name by president
                    or other authorized officer.  If a partnership,  please sign
                    in partnership name by authorized person.)

                    Date:
                         -------------------------------------------------------


                     -----------------------------------------------------------
                                             Sign Here

                     -----------------------------------------------------------
                                   Signature (if held jointly)

                     -----------------------------------------------------------
                         Capacity (Title or Authority, i.e. Executor, Trustee)

                     PLEASE SIGN, DATE AND MAIL YOUR PROXY TODAY.


                                     - 21 -



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