ENZON INC
10-Q, 1998-02-13
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                                    FORM 10-Q


                QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE
                         SECURITIES EXCHANGE ACT OF 1934



For Quarter Ended December 31, 1997                  Commission File No. 0-12957


                                   ENZON, INC.
             (Exact name of registrant as specified in its charter)



               Delaware                                          22-2372868
(State or other jurisdiction of                                 (IRS Employer
 incorporation or organization)                              Identification No.)

20 Kingsbridge Road, Piscataway, New Jersey                       08854
(Address of principal executive offices)                        (Zip Code)

                                 (732) 980-4500
              (Registrant's telephone number, including area code:)



Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the  preceding 12 months (or for such  shorter  period that the  registrant  was
required  to file  such  reports),  and  (2) has  been  subject  to such  filing
requirements for the past 90 days.


Yes _X_    No ___


The number of shares of common stock, $.01 par value, outstanding as of February
4, 1998 was 31,130,417 shares.



<PAGE>




PART I FINANCIAL INFORMATION
Item 1. Financial Statements

                           ENZON, INC AND SUBSIDIARIES
                      CONSOLIDATED CONDENSED BALANCE SHEETS
                       December 31, 1997 and June 30, 1997

<TABLE>
<CAPTION>
                                                                  December 31,       June 30,
ASSETS                                                               1997              1997
                                                                 -------------    -------------
                                                                  (unaudited)           *
<S>                                                              <C>              <C>          
Current assets:
  Cash and cash equivalents                                      $   8,719,548    $   8,315,752
  Accounts receivable                                                2,735,867        2,433,762
  Inventories                                                          671,523          859,873
  Other current assets                                                 264,111           87,732
                                                                 -------------    -------------
     Total current assets                                           12,391,049       11,697,119
                                                                 -------------    -------------
Property and equipment                                              15,052,998       15,676,525
  Less accumulated depreciation and amortization                    12,878,551       12,923,802
                                                                 -------------    -------------
                                                                     2,174,447        2,752,723
                                                                 -------------    -------------
Other assets:
  Investments                                                           74,416           78,293
  Other assets, net                                                     41,484           34,575
  Patents, net                                                       1,365,329        1,442,568
                                                                 -------------    -------------
                                                                     1,481,229        1,555,436
                                                                 -------------    -------------
Total assets                                                     $  16,046,725    $  16,005,278
                                                                 =============    =============



LIABILITIES AND STOCKHOLDERS' EQUITY

Current liabilities:
  Accounts payable                                               $   1,340,289    $   1,910,737
  Accrued expenses                                                   3,646,667        3,504,966
                                                                 -------------    -------------
     Total current liabilities                                       4,986,956        5,415,703
                                                                 -------------    -------------
  Accrued rent                                                         806,693          870,012
  Royalty advance - RPR                                                625,947        1,177,682
                                                                 -------------    -------------
                                                                     1,432,640        2,047,694
                                                                 -------------    -------------
Commitments and contingencies
Stockholders' equity:
  Preferred stock-$.01 par value, authorized 3,000,000 shares:
   issued and outstanding 108,000 shares at December 31,
   1997 and 109,000 shares at June 30, 1997 (liquidation
   preference aggregating $2,700,000 at December 31, 1997
   and $2,725,000 at June 30, 1997)                                      1,080            1,090
  Common stock-$.01 par value, authorized 60,000,000 shares:
   issued and outstanding 31,030,167 shares at December
   31, 1997 and 30,797,735 shares at June 30, 1997                     310,302          307,977
  Additional paid-in capital                                       122,052,916      121,426,159
  Accumulated deficit                                             (112,737,169)    (113,193,345)
                                                                 -------------    -------------
Total stockholders' equity                                           9,627,129        8,541,881
                                                                 -------------    -------------
Total liabilities and stockholders' equity                       $  16,046,725    $  16,005,278
                                                                 =============    =============
</TABLE>

*Condensed from audited financial statements.

The  accompanying  notes are an integral  part of these  unaudited  consolidated
condensed financial statements.

                                        2

<PAGE>




                                   ENZON, INC.
                 CONSOLIDATED CONDENSED STATEMENTS OF OPERATIONS
          Three Months and Six Months Ended December 31, 1997 and 1996
                                   (Unaudited)

<TABLE>
<CAPTION>
                                                      Three months ended             Six months ended
                                                 December 31,   December 31,   December 31,   December 31,
                                                     1997           1996           1997          1996
                                                 -----------    -----------    -----------    -----------
<S>                                              <C>            <C>            <C>            <C>        
Revenues
  Sales                                          $ 4,139,841    $ 3,553,975    $ 6,604,475    $ 6,274,566
  Contract revenue                                   107,500          5,010      2,312,609      1,099,309
                                                 -----------    -----------    -----------    -----------
     Total revenues                                4,247,341      3,558,985      8,917,084      7,373,875
                                                 -----------    -----------    -----------    -----------
Costs and expenses
  Cost of sales                                    1,134,682        994,325      1,739,390      1,980,314
  Research and development expenses                1,985,738      1,980,063      4,132,707      4,409,834
  Selling, general and administrative expenses     1,498,242      1,453,545      2,826,684      2,729,612
                                                 -----------    -----------    -----------    -----------
     Total costs and expenses                      4,618,662      4,427,933      8,698,781      9,119,760
                                                 -----------    -----------    -----------    -----------
       Operating income (loss)                      (371,321)      (868,948)       218,303     (1,745,885)
                                                 -----------    -----------    -----------    -----------
Other income (expense)
  Interest and dividend income                       150,763        162,770        265,563        319,911
  Interest expense                                    (4,467)        (4,847)       (10,905)       (11,600)
  Other                                               (1,783)           180         (1,845)         8,115
                                                 -----------    -----------    -----------    -----------
                                                     144,513        158,103        252,813        316,426
                                                 -----------    -----------    -----------    -----------
     Net income (loss)                           ($  226,808)   ($  710,845)   $   471,116    ($1,429,459)
                                                 ===========    ===========    ===========    ===========
Basic earnings (loss) per common share           ($     0.01)   ($     0.03)   $      0.01    ($     0.05)
                                                 ===========    ===========    ===========    ===========
Diluted earnings (loss) per common share         ($     0.01)   ($     0.03)   $      0.01    ($     0.05)
                                                 ===========    ===========    ===========    ===========
</TABLE>












The  accompanying  notes are an integral  part of these  unaudited  consolidated
condensed financial statements.

                                        3

<PAGE>

                          ENZON, INC. AND SUBSIDIARIES
                 CONSOLIDATED CONDENSED STATEMENTS OF CASH FLOWS
                   Six Months Ended December 31, 1997 and 1996
                                   (Unaudited)

<TABLE>
<CAPTION>
                                                                          Six Months Ended

                                                                    December 31,    December 31,
                                                                        1997           1996
                                                                    ------------    ------------
<S>                                                                 <C>             <C>          
Cash flows from operating activities:
  Net income (loss)                                                 $    471,116    ($ 1,429,459)
  Adjustment for depreciation and amortization                           650,404         886,729
  Loss on retirement of equipment                                          1,845            --
  Non-cash expense for issuance of common stock and stock options        111,882         121,838
  Decrease in accrued rent                                               (63,319)        (47,577)
  Decrease in royalty advance - RPR                                     (871,146)       (541,476)
  Changes in assets and liabilities                                     (401,219)       (708,793)
                                                                    ------------    ------------
  Net cash used in operating activities                                 (100,437)     (1,718,738)
                                                                    ------------    ------------
Cash flows from investing activities:
  Capital expenditures                                                   (79,863)       (602,700)
  Proceeds from sale of equipment                                         83,129            --
                                                                    ------------    ------------
  Net cash provided by (used in) investing activities                      3,266        (602,700)
                                                                    ------------    ------------
Cash flows from financing activities:
  Proceeds from issuance of common stock                                 502,250           8,032
  Principal payments of obligations under capital leases                  (1,283)         (1,139)
                                                                    ------------    ------------
  Net cash provided by financing activities                              500,967           6,893
                                                                    ------------    ------------
  Net increase (decrease) in cash and cash equivalents                   403,796      (2,314,545)
  Cash and cash equivalents at beginning of period                     8,315,752      12,666,050
                                                                    ------------    ------------
  Cash and cash equivalents at end of period                        $  8,719,548    $ 10,351,505
                                                                    ============    ============
</TABLE>





The  accompanying  notes are an integral  part of these  unaudited  consolidated
condensed financial statements.




                                        4

<PAGE>



                          ENZON, INC. AND SUBSIDIARIES
              Notes To Consolidated Condensed Financial Statements
                                   (Unaudited)


(1)  Organization and Basis of Presentation

     The  unaudited   consolidated  condensed  financial  statements  have  been
prepared  from the  books  and  records  of  Enzon,  Inc.  and  subsidiaries  in
accordance with generally accepted  accounting  principles for interim financial
information.  Accordingly,  they  do not  include  all of  the  information  and
footnotes  required by generally  accepted  accounting  principles  for complete
financial statements. In the opinion of management,  all adjustments (consisting
only of  normal  and  recurring  adjustments)  considered  necessary  for a fair
presentation  have been included.  Certain prior year balances were reclassified
to  conform  to the  1997  presentation.  Interim  results  are not  necessarily
indicative  of the results that may be expected for the year,  and as such,  the
Company has not recorded a tax provision as it does not anticipate net income to
be recognized for the year ending June 30, 1998.

(2)  Earnings (Loss) Per Share

     Basic  earnings  (loss) per common share is based on the net income  (loss)
for the relevant  period,  adjusted for cumulative  undeclared  preferred  stock
dividends of $54,000 and $55,000 for the three  months  ended  December 31, 1997
and 1996,  and $108,000 and $109,000 for the six months ended  December 31, 1997
and 1996, respectively,  divided by the weighted average number of common shares
issued and outstanding during the period.

     Diluted  earnings per common  share for the six months  ended  December 31,
1997 is based on net income,  adjusted for cumulative undeclared preferred stock
dividends of $108,000 for the six months ended December 31, 1997, divided by the
weighted  average  number of common  shares  issued and  outstanding  during the
period, plus the exercise or conversion of all dilutive potential common shares.

     Diluted loss per common share for the three months ended  December 31, 1997
and 1996 and the six months ended  December  31, 1996,  is based on the net loss
for the relevant  period  adjusted for  cumulative  undeclared  preferred  stock
dividends of $54,000 and $55,000 for the three  months  ended  December 31, 1997
and 1996, respectively, and $109,000 for the six months ended December 31, 1996,
divided by the weighted  average number of common shares issued and  outstanding
during the period.  The exercise or conversion of all dilutive  potential common
shares is not included,  due to the net loss recorded for the three months ended
December 31, 1997 and 1996 and the six months ended December 31, 1996.



















                                        5

<PAGE>



                          ENZON, INC. AND SUBSIDIARIES
         Notes To Consolidated Condensed Financial Statements, Continued
                                   (Unaudited)


     The  following  represents  the weighted  average  number of common  shares
outstanding  for the three  and six  months  ended  December  31,  1997 and 1996
diluted earnings (loss) per common share calculation:

<TABLE>
<CAPTION>
                                        Three months ended              Six months ended
                                     December 31,  December 31,   December 31,  December 31,
                                         1997         1996            1997         1996
                                      ----------   ----------      ----------   ----------
<S>                                   <C>          <C>             <C>          <C>
Weighted average number of                                         
 common shares issued and                                          
 outstanding                          30,975,856   27,882,828      30,918,228   27,794,716
                                                                   
   Weighted average shares issued                                  
     upon the exercise of dilutive                                 
     options and warrants based on                                 
     the Treasury Stock Method              --           --         1,677,509         --
                                      ----------   ----------      ----------   ----------
Weighted average number of                                         
 common shares issued and                                          
 outstanding and dilutive potential                                
 common shares                        30,975,856   27,882,828      32,595,737   27,794,716
                                      ==========   ==========      ==========   ==========
</TABLE>

(3)  Inventories

     The composition of inventories at December 31, 1997 and June 30, 1997 is as
follows:

                                                     December 31,       June 30,
                                                        1997              1997
                                                      --------          --------
         Raw materials                                $327,000          $269,000
         Work in process                               109,000           269,000
         Finished goods                                236,000           322,000
                                                      --------          --------
                                                      $672,000          $860,000
                                                      ========          ========

(4)  Cash Flow Information

     The Company considers all highly liquid securities with original maturities
of three months or less to be cash equivalents.  Cash payments for interest were
approximately $11,000 and $12,000 for the six months ended December 31, 1997 and
1996,  respectively.  There were no income tax payments  made for the six months
ended December 31, 1997 and 1996.

     During the six months ended  December  31,  1997,  1,000 shares of Series A
Cumulative  Convertible  Preferred  Stock  ("Series  A  Preferred  Stock")  were
converted to 2,272 shares of Common Stock.  Accrued  dividends of $15,000 on the
Series A Preferred Stock that converted during the six months ended December 31,
1997,  were settled by issuing  1,358  shares of Common Stock and cash  payments
totaling  $10 for  fractional  shares.  There  were no  conversions  of Series A
Preferred  Stock during the six months ended  December 31, 1996.  During the six
months ended December 31, 1996, 24,260 shares of Series B Convertible  Preferred
Stock were converted into 1,287,213 shares of Common Stock.



                                        6

<PAGE>



                          ENZON, INC. AND SUBSIDIARIES
         Notes To Consolidated Condensed Financial Statements, Continued
                                   (Unaudited)


A  cash  payment  of  $2.00  was  made  for  fractional  shares  related  to the
conversions. These transactions are non-cash financing activities.

(5)  Non-Qualified Stock Option Plan

     During the six months ended  December 31, 1997,  the Company issued 456,000
stock  options  at an  average  exercise  price of $5.82  per  share  under  the
Company's  Non-Qualified  Stock  Option Plan,  as amended,  of which 80,000 were
granted to executive officers of the Company. None of the options granted during
the period are  exercisable  as of December 31,  1997.  All options were granted
with  exercise  prices  that  equaled or exceeded  the fair market  value of the
underlying stock on the date of grant.

(6)  Subsequent Events

     During January 1998, the Company amended its long-term supply agreement for
unmodified  L-asparaginase,  one of the raw materials used in ONCASPAR  produced
for the North  American  market.  The amendment  extended the term of the supply
agreement  and the time for the Company to fulfill its  remaining  $1,300,000 in
minimum purchase  commitments  until December 31, 1999. In consideration for the
extension,  the Company paid $75,000 and made an advance  payment of  $1,300,000
for the remaining minimum purchase commitment under the agreement.  The supplier
will deliver the prepaid inventory at the Company's request through December 31,
1999.  Any inventory  that is not taken by the Company by December 31, 1999 will
be forfeited. These payments were made in January 1998.


                                        7

<PAGE>



Item 2. Management's  Discussion and Analysis of Financial Condition and Results
of Operations

Information contained herein contains "forward-looking  statements" which can be
identified  by the  use  of  forward-looking  terminology  such  as  "believes,"
"expects,"  "may," "will," "should," or "anticipates" or the negative thereof or
other  variations  thereon  or  comparable  terminology,  or by  discussions  of
strategy.  No  assurance  can be given  that the future  results  covered by the
forward-looking  statements  will be achieved.  The matters set forth in Exhibit
99.0 to the Company's  Annual Report on Form 10-K for the fiscal year ended June
30, 1997,  which is  incorporated  herein by  reference,  constitute  cautionary
statements  identifying  important factors with respect to such  forward-looking
statements,  including certain risks and uncertainties,  that could cause actual
results  to  vary  materially   from  the  future  results   indicated  in  such
forward-looking  statements.  Other factors  could also cause actual  results to
vary  materially  from the  future  results  indicated  in such  forward-looking
statements.

Results of Operations

Three months ended December 31, 1997 vs. Three months ended December 31, 1996

Revenues. Revenues for the three months ended December 31, 1997 increased by 19%
to  $4,247,000  as  compared  to  $3,559,000  for the same  period in 1996.  The
components of revenues are sales and contract  revenues.  Sales increased by 16%
to  $4,140,000  for the three  months  ended  December  31,  1997 as compared to
$3,554,000 for the same period in the prior year, due to increased revenues from
ONCASPAR(R),   which  is   marketed   in  the  U.S.   by   Rhone-Poulenc   Rorer
Pharmaceuticals,  Inc. ("RPR"),  and increased ADAGEN(R) sales resulting from an
increase in patients  receiving ADAGEN.  ADAGEN sales for the three months ended
December  31,  1997 and  1996  were  $2,800,000  and  $2,328,000,  respectively.
ONCASPAR  revenues are comprised of manufacturing  revenues as well as royalties
on sales of ONCASPAR by RPR. ONCASPAR  revenues  increased due to an increase in
royalties on sales of ONCASPAR by RPR which was partially offset by a decline in
manufacturing  revenues  resulting from the timing of ONCASPAR shipments made to
RPR.  During the three months ended  December 31, 1997 and 1996, the Company had
export  sales of  $642,000  and  $589,000,  respectively.  Sales in Europe  were
$489,000 and  $479,000  for the three  months ended  December 31, 1997 and 1996,
respectively.

Cost of Sales.  Cost of sales,  as a percentage  of sales,  remained  relatively
constant at 27% for the three months ended  December 31, 1997 as compared to 28%
for the same period in 1996.  During the quarter  ended  December 31, 1997,  the
Company  utilized  approximately  10%  of its  manufacturing  capacity  for  the
production of its approved products.

Research and Development. Research and development expenses for the three months
ended  December 31, 1997 remained  relatively  flat at $1,986,000 as compared to
$1,980,000 for the same period in 1996.

Selling,   General   and   Administrative   Expenses.   Selling,   general   and
administrative  expenses for the three months ended  December 31, 1997  remained
relatively  unchanged  at  $1,498,000,  as compared to  $1,454,000  for the same
period in 1996.

Other Income/Expense.  Other income/expense  decreased to $145,000 for the three
months ended  December 31, 1997 as compared to $158,000 for the same period last
year. The decrease was  attributable  to a decrease in interest  income due to a
decrease in interest bearing investments.

Six months ended December 31, 1997 vs. Six months ended December 31, 1996

Revenues.  Revenues for the six months ended  December 31, 1997 increased by 21%
to  $8,917,000  as  compared  to  $7,374,000  for the same  period in 1996.  The
components of revenues are sales and contract revenues. Sales increased by 5% to
$6,604,000  for the six months ended December 31, 1997 as compared to $6,275,000
for the same  period in the  prior  year,  due to an  increase  in ADAGEN  sales
resulting from an increase in patients receiving ADAGEN which was offset in part
by  a  decrease  in  ONCASPAR  revenue.   ONCASPAR  revenues  are  comprised  of
manufacturing  revenues  as well as  royalties  on  sales  of  ONCASPAR  by RPR.
ONCASPAR revenues decreased due to a decline in manufacturing  revenue resulting
from the timing of ONCASPAR shipments made to RPR. The decrease in manufacturing
revenue was

                                        8

<PAGE>



partially offset by increased  royalties due to an increase in sales of ONCASPAR
by RPR.  ADAGEN sales for the six months  ended  December 31, 1997 and 1996 were
$4,994,000 and  $4,453,000,  respectively.  Contract  revenue for the six months
ended December 31, 1997  increased to $2,313,000,  as compared to $1,099,000 for
the same period in 1996.  The  increase  was  principally  due to an increase in
milestone  payments  received  under  the  Company's   licensing  agreement  for
PEG-Intron A with Schering-Plough  Corporation  ("Schering-Plough").  During the
six months  ended  December  31,  1997,  the Company  recognized  $2,200,000  in
milestone payments received as a result of Schering-Plough  advancing PEG-Intron
A  into  a  Phase  III  clinical  trial.  PEG-Intron  A is a  modified  form  of
Schering-Plough's  INTRON(R)A  (interferon alfa-2b,  recombinant),  developed by
Enzon to have  longer-acting  properties.  INTRON A is a genetically  engineered
anticancer   and  antiviral   agent,   developed   and  marketed   worldwide  by
Schering-Plough  Corporation.  INTRON A generated $524 million in sales in 1996.
The worldwide market for alpha interferon is in excess of $1 billion.  Under the
Company's licensing  agreement,  Enzon is entitled to royalties on product sales
and has  the  option  to  become  Schering-Plough's  exclusive  manufacturer  of
PEG-Intron A for the U.S. market.  During the prior year, the Company received a
$1,000,000 milestone payment under the licensing agreement with Schering-Plough.
During the six months ended  December 31, 1997 and 1996,  the Company had export
sales of $1,127,000 and $1,171,000,  respectively. Sales in Europe were $848,000
and $991,000 for the six months ended December 31, 1997 and 1996, respectively.

Cost of Sales. Cost of sales, as a percentage of sales, decreased to 26% for the
six months  ended  December  31,  1997 as compared to 32% for the same period in
1996.  The  decrease  was  due  primarily  to  the  prior  year's  write-off  of
approximately $200,000 in excess ONCASPAR raw material. During January 1998, the
Company amended its supply agreement for this material which extended the period
available to the Company to accept delivery of its remaining purchase commitment
through  1999,  in exchange for the advance  payment of the  remaining  purchase
commitment.  While it is possible that the Company may incur  similar  losses on
its remaining purchase  commitment under the supply agreement,  the Company does
not consider such losses  probable,  nor can the amount of any loss which may be
incurred  in the  future  presently  be  estimated  due to a number of  factors,
including,  but not limited to, potential increased demand for ONCASPAR from RPR
or expansion into  additional  markets  outside the U.S. If the Company does not
achieve  increases in sales of ONCASPAR beyond current  levels,  a loss would be
incurred on the remaining purchase commitment.

Research and Development.  Research and development  expenses for the six months
ended  December 31, 1997 decreased by 6% to $4,133,000  from  $4,410,000 for the
same period in 1996.  This  decrease was primarily due to reductions in wage and
consulting  expenses due to the  Company's  continued  focus on key  development
programs, principally in the clinical and scientific administration areas.

Selling,   General   and   Administrative   Expenses.   Selling,   general   and
administrative  expenses  for the six months ended  December  31, 1997  remained
relatively  consistent at  $2,827,000,  as compared to  $2,730,000  for the same
period in 1996.

Other Income/Expense.  Other income/expense decreased by $63,000 to $253,000 for
the six months  ended  December  31, 1997 as  compared to $316,000  for the same
period last year. The decrease was attributable to a decrease in interest income
due to a decrease in interest bearing investments.

         In February  1997,  the  Financial  Accounting  Standards  Board issued
Statements of Financial  Accounting  Standards No. 128 (SFAS 128), "Earnings Per
Share". SFAS 128 establishes standards for computing and presenting earnings per
share.  In accordance  with the effective date of SFAS 128, the Company  adopted
SFAS 128 as of December 31, 1997.

Liquidity and Capital Resources

     Enzon had $8,720,000 in cash and cash  equivalents as of December 31, 1997.
The Company  invests its excess cash in a  portfolio  of  high-grade  marketable
securities and United States government-backed securities.

     The Company's  cash reserves as of December 31, 1997  increased by $404,000
from June 30, 1997.  The increase in cash  reserves was  principally  due to net
income recorded for the six months ended December 31, 1997.

     The Company's exclusive U.S. marketing rights license with RPR for ONCASPAR
provides for a payment of

                                        9

<PAGE>



$3,500,000 in advance  royalties  which was received in January 1995.  Under the
agreement, as amended,  royalties will be offset against a credit of $5,970,000,
which  represents the royalty advance plus  reimbursement of certain amounts due
RPR under the previous agreement and interest expense, before cash payments will
be made  under  the  agreement.  The  royalty  advance  is shown as a long  term
liability with the corresponding current portion included in accrued expenses on
the consolidated  condensed  balance sheets and will be reduced as royalties are
recognized  under the  agreement.  Through  December 31,  1997,  an aggregate of
$3,863,000  in  royalties  payable by RPR have been offset  against the original
credit.

     As of December 31, 1997, 941,808 shares of Series A Cumulative  Convertible
Preferred Stock ("Series A Preferred  Stock") have been converted into 3,095,683
shares of the Company's common stock (the "Common Stock").  Accrued dividends on
the  converted  Series A Preferred  Stock in the  aggregate of  $1,807,000  were
settled by the issuance of 233,741 shares of Common Stock.  The Company does not
presently  intend to pay cash dividends on the Series A Preferred  Stock.  As of
December 31, 1997,  there were $1,679,000 of accrued and unpaid dividends on the
Series A Preferred Stock. These dividends are payable in cash or Common Stock at
the Company's  option and accrue on the outstanding  Series A Preferred Stock at
the rate of $216,000 per year.

     To date, the Company's sources of cash have been the proceeds from the sale
of its stock through public and private  placements,  sales of ADAGEN,  sales of
ONCASPAR,  sales of its products for research  purposes,  contract  research and
development fees, technology transfer and license fees and royalty advances. The
Company's  current  sources of  liquidity  are its cash,  cash  equivalents  and
interest earned on such cash reserves, sales of ADAGEN, sales of ONCASPAR, sales
of its products for research purposes and license fees. Management believes that
its current sources of liquidity will be sufficient to meet its anticipated cash
requirements,  based on current spending levels,  for approximately the next two
years.

         Upon exhaustion of the Company's  current cash reserves,  the Company's
continued  operations will depend on its ability to realize significant revenues
from the commercial sale of its products,  raise additional funds through equity
or debt  financing,  or obtain  significant  licensing,  technology  transfer or
contract  research and  development  fees.  There can be no assurance that these
sales, financings or revenue generating activities will be successful.

Item 3.  Quantitative and Qualitative Disclosures About Market Risk

     Not applicable.


                                       10

<PAGE>



PART II OTHER INFORMATION

Item 4. Submission of Matters to a Vote of Security Holders

     (a)  An annual meeting of stockholders was held on December 2, 1997.

     (b)  The directors  elected at the annual meeting were Randy H. Thurman and
          A.M.  "Don"  MacKinnon.  The term of office as a director  for each of
          Rolf A.  Classon,  Dr.  Rosina B.  Dixon,  Robert  LeBuhn and Peter G.
          Tombros continued after the annual meeting.

     (c)  The  matters  voted upon at the annual  meeting and the results of the
          voting,  including  broker non-votes where  applicable,  are set forth
          below.

          (i)  The  stockholders  voted  21,967,300  shares in favor and 127,057
               shares  against  with respect to the election of Randy H. Thurman
               as a Class II director of the  Company and  21,958,668  shares in
               favor and 135,689  shares against with respect to the election of
               A.M.  "Don"  MacKinnon  as a Class II  director  of the  Company.
               Broker non-votes were not applicable.

          (ii) The  stockholders  voted  19,609,594  shares in favor,  2,484,763
               shares  against with respect to a proposal to amend the Company's
               Certificate of Incorporation to increase the number of authorized
               shares of Common Stock from forty million  (40,000,000)  to sixty
               million (60,000,000).

          (iii)The  stockholders  voted  18,861,706  shares in favor and 817,777
               shares against with respect to a proposal to approve an amendment
               to the Company's  Non-Qualified Stock Option Plan, as amended, to
               conform the Plan to changes made to the rules under Section 16(b)
               of the Securities and Exchange Act of 1934. Broker non-votes were
               not applicable.

          (iv) The  stockholders  voted  21,896,815  shares in favor and 197,542
               against  with  respect to a proposal to ratify the  selection  of
               KPMG  Peat  Marwick  LLP  to  audit  the  Company's  consolidated
               financial  statements  for the fiscal year ending June 30,  1997.
               Broker non-votes were not applicable.



                                       11

<PAGE>



Item 6. Exhibit  and Reports on Form 8-K

     (a) Exhibits (numbered in accordance with Item 601 of Regulation S-K).

<TABLE>
<CAPTION>
                                                                                                       Page Number  
                                                                                                            or      
  Exhibit                                                                                             Incorporation 
   Number          Description                                                                         By Reference 
   ------          -----------                                                                         ------------ 
<S>           <C>                                                                                         <C>
   3(i)       Certificate of Incorporation, as amended                                                       ^
   3(ii)      By-laws, as amended                                                                           *(4.2)
   3(iii)     Certificate of Designations, Preferences and Rights of Series D Convertible
                Preferred Stock                                                                           ^^^^3(iii)
   3(iv)      Amendment to Certificate of Incorporation dated January 5, 1998                                 o
  10.0        Employment Agreement dated March 25, 1994 with Peter G. Tombros                               #(10.17)
  10.1        Form of Change of Control Agreements dated as of January 20, 1995 entered
                into with the Company's Executive Officers                                                  ~(10.2)
  10.2        Lease - 300-C Corporate Court, South
                   Plainfield, New Jersey                                                                 ***(10.3)
  10.4        Lease Termination Agreement dated March 31, 1995 for
                20 Kingsbridge Road and 40 Kingsbridge Road, Piscataway, New Jersey                         ~(10.6)
  10.5        Option Agreement dated April 1, 1995 regarding 20 Kingsbridge Road,
                Piscataway, New Jersey                                                                      ~(10.7)
  10.6        Form of Lease - 40 Cragwood Road, South
                   Plainfield, New Jersey                                                                ****(10.9)
  10.7        Lease 300A-B Corporate Court, South Plainfield, New Jersey                                  +++(10.10)
  10.8        Stock Purchase Agreement dated March 5, 1987
                   between the Company and Eastman Kodak Company                                         ****(10.7)
  10.9        Amendment dated June 19, 1989 to Stock Purchase
                   Agreement between the Company and
                   Eastman Kodak Company                                                                   **(10.10)
 10.10        Form of Stock Purchase Agreement between the Company
                   and the purchasers of the Series A Cumulative
                   Convertible Preferred Stock                                                              +(10.11)
 10.11        Amendment to License Agreement and Revised License Agreement
                   between the Company and RCT dated
                   April 25, 1985                                                                        ++++(10.5)
 10.12        Amendment dated as of May 3, 1989 to Revised License Agreement
                   dated April 25, 1985 between the Company and Research
                   Corporation                                                                             **(10.14)
 10.13        License Agreement dated September 7, 1989 between the Company and
               Research Corporation Technologies, Inc.                                                     **(10.15)
 10.14        Master Lease Agreement and Purchase Leaseback Agreement dated
                   October 28, 1994 between the Company and Comdisco, Inc.                                 ##(10.16)
 10.15        Employment Agreement with Peter G. Tombros dated as of
                   April 5, 1997                                                                         ^^^^(10.15)
 10.16        Stock Purchase Agreement dated as of June 30, 1995                                          ~~~(10.16)
 10.17        Securities Purchase Agreement dated as of January 31, 1996                                  ~~~(10.17)
 10.18        Registration Rights Agreements dated as of January 31, 1996                                 ~~~(10.18)
 10.19        Warrants dated as of February 7, 1996 and issued pursuant to the Securities
                   Purchase Agreement dated as of January 31, 1996                                        ~~~(10.19)
</TABLE>


                                       12

<PAGE>


<TABLE>
<S>           <C>                                                                                      <C>

 10.20        Securities Purchase Agreement dated as of March 15, 1996                                      ^(10.20)
 10.21        Registration Rights Agreement dated as of March 15, 1996                                      ^(10.21)
 10.22        Warrant dated as of March 15, 1996 and issued pursuant to the Securities Purchase
               Agreement dated as of March 15, 1996                                                         ^(10.22)
 10.23        Amendment dated March 25, 1994 to License Agreement dated
                September 7, 1989 between the Company and Research Corporation
                Technologies, Inc.                                                                         ^^(10.23)
 10.24        Independent Directors' Stock Plan                                                            ^^(10.24)
 10.25        Stock Exchange Agreement dated February 28, 1997, by and between the
                Company and GFL Performance Fund Ltd.                                                     ^^^(10.25)
 10.26        Agreement Regarding Registration Rights Under Registration Rights Agreement
                dated March 10, 1997, by and between the Company and Clearwater Fund IV
                LLC                                                                                       ^^^(10.26)
  27.0        Financial Data Schedule                                                                         o
  99.0        Factors to Consider in Connection with Forward-Looking Statements                          ^^^^(99.0)


</TABLE>

o       Filed herewith.

*       Previously filed as an exhibit to the Company's  Registration  Statement
        on Form S-2 (File No.  33-34874)  and  incorporated  herein by reference
        thereto.

**      Previously filed as exhibits to the Company's Annual Report on Form 10-K
        for the  fiscal  year  ended June 30,  1989 and  incorporated  herein by
        reference thereto.

***     Previously filed as an exhibit to the Company's  Registration  Statement
        on Form S-18 (File No. 2-88240-NY) and incorporated  herein by reference
        thereto.

****    Previously filed as exhibits to the Company's  Registration Statement on
        Form S-1 (File No.  2-96279) filed with the Commission and  incorporated
        herein by reference thereto.

+       Previously filed as an exhibit to the Company's  Registration  Statement
        on  Form  S-1  (File  No.   33-39391)  filed  with  the  Commission  and
        incorporated herein by reference thereto.

+++     Previously  filed as an exhibit to the  Company's  Annual Report on Form
        10-K for the fiscal year ended June 30, 1993 and incorporated  herein by
        reference thereto.

++++    Previously  filed as an exhibit to the  Company's  Annual Report on Form
        10-K for the fiscal year ended June 30, 1985 and incorporated  herein by
        reference thereto.

#       Previously  filed as an exhibit to the Company's  Current Report on Form
        8-K dated April 5, 1994 and incorporated herein by reference thereto.

##      Previously filed as an exhibit to the Company's Quarterly Report on Form
        10-Q for the quarter ended December 31, 1994 and incorporated  herein by
        reference thereto.

~       Previously filed as an exhibit to the Company's Quarterly Report on Form
        10-Q for the quarter  ended March 31,  1995 and  incorporated  herein by
        reference thereto.

~~      Previously  filed as an exhibit to the  Company's  Annual Report on Form
        10-K for the fiscal year ended June 30, 1995 and incorporated  herein by
        reference thereto.

~~~     Previously filed as an exhibit to the Company's Quarterly Report on Form
        10-Q for the quarter ended December 31, 1995 and incorporated  herein by
        reference thereto.

                                       13

<PAGE>

^       Previously filed as an exhibit to the Company's Quarterly Report on Form
        10-Q for the quarter  ended March 31,  1996 and  incorporated  herein by
        reference thereto.

^^      Previously filed as an exhibit to the Company's Quarterly Report on Form
        10-Q for the quarter ended December 31, 1996 and incorporated  herein by
        reference thereto.

^^^     Previously filed as an exhibit to the Company's Quarterly Report on Form
        10-Q for the quarter  ended March 31,  1997 and  incorporated  herein by
        reference thereto.

^^^^    Previously  filed as an exhibit to the  Company's  Annual Report on Form
        10-K for the  year  ended  June 30,  1997  and  incorporated  herein  by
        reference thereto.

(b)  Reports on Form 8-K

     None

                                       14

<PAGE>



                                   SIGNATURES

     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
Registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned thereunto duly authorized.

                                            ENZON, INC.
                                            (Registrant)



Date: February 13, 1998                     By: /s/Peter G. Tombros
                                               ------------------------
                                            Peter G. Tombros
                                            President and Chief Executive
                                             Officer



                                            By: /s/Kenneth J. Zuerblis
                                                ------------------------
                                            Kenneth J. Zuerblis
                                            Vice President, Finance and
                                             Chief Financial Officer


                                       15

<TABLE> <S> <C>


<ARTICLE>                     5
<LEGEND>
     This schedule  contains summary  financial  information  extracted from the
Enzon, Inc. and Subsidiaries Consolidated Condensed Balance Sheet as of December
31, 1997 and the  Consolidated  Condensed  Statement of Operations for the three
and six months  ended  December  31, 1997 and is  qualified  in its  entirety by
reference to such financial statements.
</LEGEND>

       
<S>                                       <C>                    <C>
<PERIOD-TYPE>                             3-MOS                  6-MOS
<FISCAL-YEAR-END>                             JUN-30-1998             JUN-30-1998
<PERIOD-END>                                  DEC-31-1997             DEC-31-1997
<CASH>                                          8,719,548              $8,719,548
<SECURITIES>                                            0                       0
<RECEIVABLES>                                   2,735,867               2,735,867
<ALLOWANCES>                                            0                       0
<INVENTORY>                                       671,523                 671,523
<CURRENT-ASSETS>                               12,391,049              12,391,049
<PP&E>                                         15,052,998              15,052,998
<DEPRECIATION>                                 12,878,551              12,878,551
<TOTAL-ASSETS>                                 16,046,725              16,046,725
<CURRENT-LIABILITIES>                           4,986,956               4,986,956
<BONDS>                                                 0                       0
                                   0                       0
                                         1,080                   1,080
<COMMON>                                          310,302                 310,302
<OTHER-SE>                                      9,315,747               9,315,747
<TOTAL-LIABILITY-AND-EQUITY>                   16,046,725              16,046,725
<SALES>                                         4,139,841               6,604,475
<TOTAL-REVENUES>                                4,247,341               8,917,084
<CGS>                                           1,134,682               1,739,390
<TOTAL-COSTS>                                   4,618,662               8,698,781
<OTHER-EXPENSES>                                        0                       0
<LOSS-PROVISION>                                        0                       0
<INTEREST-EXPENSE>                                  4,467                  10,905
<INCOME-PRETAX>                                 (226,808)                 471,116
<INCOME-TAX>                                            0                       0
<INCOME-CONTINUING>                             (226,808)                 471,116
<DISCONTINUED>                                          0                       0
<EXTRAORDINARY>                                         0                       0
<CHANGES>                                               0                       0
<NET-INCOME>                                    (226,808)                 471,116
<EPS-PRIMARY>                                      (0.01)                    0.01
<EPS-DILUTED>                                      (0.01)                    0.01
                                               


</TABLE>


                            CERTIFICATE OF AMENDMENT

                                       OF

                          CERTIFICATE OF INCORPORATION

                                       OF

                                   ENZON, INC.

                            * * * * * * * * * * * * *

     Enzon,  Inc., a corporation  organized and existing  under and by virtue of
the General Corporation Law of the State of Delaware (the  ACorporation@),  DOES
HEREBY CERTIFY:

     FIRST: That the Board of Directors of said Corporation, at a meeting of its
members,  adopted  resolutions  proposing and declaring  advisable the following
amendments to the Certificate of Incorporation of said Corporation:

          RESOLVED,  that the first sentence of Article 4 of the  Certificate of
          Incorporation be amended to read in its entirety as set forth below:

               "4. Number of Shares. The total number of shares of capital stock
          which the  Corporation  shall have  authority to issue is  sixty-three
          million  (63,000,000)  shares,  of which  sixty  million  (60,000,000)
          shares  shall be Common  Stock,  par value $.01 per  share,  and three
          million  (3,000,000)  shares shall be Preferred  Stock, par value $.01
          per share."

     SECOND: That the remainder of Article 4 of the Certificate of Incorporation
of said Corporation shall remain unchanged.

     THIRD:  That at the Annual Meeting of Stockholders of the Corporation,  the
holders of a majority of the outstanding stock entitled to vote thereon voted in
favor of said amendments in accordance with the provisions of Section 215 of the
General Corporation Law of the State of Delaware.

     FOURTH: That the aforesaid  amendments were duly adopted in accordance with
the applicable provisions of Sections 242 and 216 of the General Corporation Law
of the State of Delaware.



<PAGE>


     IN WITNESS WHEREOF, Enzon, Inc. has caused this certificate to be signed by
Peter G. Tombros, its President and attested to by John A. Caruso,  Secretary of
the Corporation, this 18 of December, 1997.



                                                 By:/S/PETER G. TOMBROS
                                                    --------------------------
                                                      Peter G. Tombros
                                                      President



ATTEST:


By:/S/ JOHN A. CARUSO
   ---------------------------
      John A. Caruso
      Secretary




                                       2



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