ENZON INC
DEF 14A, 1998-10-28
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                            SCHEDULE 14A INFORMATION

                Proxy Statement Pursuant to Section 14(a) of the
               Securities Exchange Act of 1934 (Amendment No. __ )

Filed by the Registrant [X] 

Filed by a Party other than the Registrant [ ]

Check the appropriate box:

[ ] Preliminary Proxy Statement

[X] Definitive Proxy Statement

[ ] Definitive Additional Materials

[ ] Soliciting Material pursuant to Rule 14a-11(c) or Rule 14a-12

                                   ENZON, INC.
                (Name of Registrant as Specified In Its Charter)

                              KEVIN T. COLLINS,ESQ.
                   (Name of Person(s) filing Proxy Statement)

Payment of Filing Fee (Check the appropriate box):

[ ] $125 per Exchange Act Rules 0-11(c)(1)(ii), 14a-6(I)(1), or 14a-6(j)(2).

[ ] $500 per  each  party  to the  controversy  pursuant  to  Exchange  Act Rule
    14a-6(I)(3).

[ ] Fee computed on table below per Exchange Act Rules 14a-6(I)(4) and 0-11.

     (1)  Title of each class of securities to which transaction applies:


          ----------------------------------------------------------------------

     (2)  Aggregate number of securities to which transaction applies:


          ----------------------------------------------------------------------

     (3)  Per unit  price  or other  underlying  value of  transaction  computed
          pursuant to Exchange Act Rule 0-11:

     (4)  Proposed maximum aggregate value of transaction:

          ----------------------------------------------------------------------

Set forth the amount on which the filing fee is calculated and
state how it was determined.

[ ]  Check box if any part of the fee is offset as provided  by  Exchange  Act
     rule  0-11(a)(2)  and identify the filing for which the  offsetting fee was
     paid  previously.  Identify the previous filing by  registration  statement
     number, or the Form or Schedule and the date of its filing.

     1)   Amount Previously Paid:

          ----------------------------------------------------------------------

     2)   Form, Schedule or Registration Statement No.:

          ----------------------------------------------------------------------

     3)   Filing Party:

          ----------------------------------------------------------------------

     4)   Date Filed:

          ----------------------------------------------------------------------

<PAGE>

                               [LOGO] ENZON, INC.

                               20 Kingsbridge Road
                          Piscataway, New Jersey 08854
                                 (732) 980-4500

                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                           TO BE HELD DECEMBER 1, 1998


To our Stockholders:

     You are hereby  notified  that the  annual  meeting  of  stockholders  (the
"Annual  Meeting")  of Enzon,  Inc.,  a  Delaware  corporation  ("Enzon"  or the
"Company")  will be held at the Embassy  Suites Hotel,  121  Centennial  Avenue,
Piscataway,  New Jersey on Tuesday,  December 1, 1998 at 10:00 a.m.  local time,
for the following purposes:

     1.   To elect two Class III  directors,  each for a term of three  years in
          accordance with the Company's Certificate of Incorporation and By-Laws
          (Proposal No. 1);

     2.   To  vote  on  a  proposal  to  approve  amendments  to  the  Company's
          Non-Qualified Stock Option Plan, as amended (Proposal No. 2);

     3.   To  ratify  the  selection  of  KPMG  Peat  Marwick  LLP,  independent
          certified  public  accountants,  to audit the  consolidated  financial
          statements  of the  Company  for the fiscal  year ending June 30, 1999
          (Proposal No. 3); and

     4.   To transact  such other matters as may properly come before the Annual
          Meeting or any adjournment thereof.

     Only holders of record of the Company's  Common  Stock,  par value $.01 per
share, and Series A Cumulative  Convertible  Preferred Stock, par value $.01 per
share,  at the close of business on October 27, 1998 are  entitled to notice of,
and to vote at the Annual Meeting.

     Enzon hopes that as many  stockholders as possible will  personally  attend
the Annual Meeting.  WHETHER OR NOT YOU PLAN TO ATTEND THE ANNUAL MEETING,  YOUR
PROXY VOTE IS IMPORTANT.  TO ASSURE YOUR  REPRESENTATION AT THE MEETING,  PLEASE
COMPLETE,  SIGN AND DATE THE  ENCLOSED  PROXY CARD AND RETURN IT PROMPTLY IN THE
ENCLOSED  ENVELOPE.  Sending in your proxy will not  prevent  you from voting in
person at the Annual Meeting.

                                             By order of the Board of Directors,



                                             John A. Caruso, Secretary

Piscataway, New Jersey
October 28, 1998

<PAGE>



                                   ENZON, INC.

                                     -------

                                 PROXY STATEMENT

                                     -------

     This Proxy  Statement is furnished in connection  with the  solicitation of
proxies for use at the annual meeting of stockholders (the "Annual Meeting ") to
stockholders of record of Enzon,  Inc.  ("Enzon" or the "Company") to be held on
Tuesday, December 1, 1998 and at any adjournment thereof. The accompanying proxy
is  solicited  by the Board of  Directors of the Company and is revocable by the
stockholder  any time before it is voted.  For more  information  concerning the
procedure for revoking the proxy see "General."  This Proxy  Statement was first
mailed to stockholders of the Company on or about November 2, 1998,  accompanied
by the Company's  Annual Report to  Stockholders  for the fiscal year ended June
30,  1998.  The  principal  executive  offices of the  Company are located at 20
Kingsbridge Road, Piscataway, New Jersey 08854, telephone (732) 980-4500.


                      OUTSTANDING SHARES AND VOTING RIGHTS

     Only holders of the Company's  common stock,  par value $.01 per share (the
"Common Stock" or "Common Shares") and Series A Cumulative Convertible Preferred
Stock,  $.01 per share (the  "Series A  Preferred  Stock" or "Series A Preferred
Shares")  outstanding  at the close of business on October 27, 1998 (the "Record
Date") are entitled to receive notice of and vote at the Annual  Meeting.  As of
the Record Date, the number and class of stock that was  outstanding and will be
entitled to vote at the meeting were 35,409,969 Common Shares and 107,000 Series
A Preferred  Shares.  Each Common Share and Series A Preferred Share is entitled
to one vote on all  matters.  No other class of  securities  will be entitled to
vote at the Annual Meeting. There are no cumulative voting rights.

     To be elected,  a director  must  receive a  plurality  of the votes of the
Common Shares and Series A Preferred Shares,  voting as a single class,  present
in person or  represented by proxy at the Annual Meeting and entitled to vote on
the election of directors.  The  affirmative  vote of at least a majority of the
Common Shares and Series A Preferred Shares, present in person or represented by
proxy at the Annual Meeting and entitled to vote thereon,  voting  together as a
single class,  is necessary for approval of Proposal No. 2 and Proposal No. 3. A
quorum is representation in person or by proxy at the Annual Meeting of at least
one-third  of  the  combined  Common  Shares  and  Series  A  Preferred   Shares
outstanding as of the Record Date.

     Pursuant to the Delaware  General  Corporation Law, only votes cast "For" a
matter  constitute  affirmative  votes.  Proxy  cards which are voted by marking
"Withheld" or "Abstain" on a particular matter are counted as present for quorum
purposes and for purposes of determining  the outcome of such matter,  but since
they are not cast "For" a particular  matter,  they will have the same effect as
negative  votes or votes  cast  "Against"  a  particular  matter.  If a  validly
executed proxy card is not marked to indicate a vote on a particular  matter and
the proxy granted  thereby is not revoked  before it is voted,  it will be voted
"For" such matter.  Where brokers are prohibited from  exercising  discretionary
authority  for  beneficial  owners  who have not  provided  voting  instructions
(commonly  referred to as "broker  non-votes"),  such broker  non-votes  will be
treated as shares that are present for purposes of determining the presence of a
quorum; however, with respect to proposals which require the affirmative vote of
a percentage of shares present at the Annual  Meeting for approval,  such broker
non-votes will be treated as not present for purposes of determining the outcome
of any such matter. With respect to proposals which require the affirmative vote
of a  percentage  of the  outstanding  shares for  approval,  since such  broker
non-votes are not cast "For" a particular matter, they will have the same effect
as negative votes or votes cast "Against" such proposals.


                                       1


<PAGE>

                     PROPOSAL NO. 1 - ELECTION OF DIRECTORS

     Pursuant to the provisions of the Company's  Certificate  of  Incorporation
and By-laws,  the Board of Directors is comprised of three classes of directors,
designated  Class I, Class II and Class III.  One class of  directors is elected
each year to hold  office for a  three-year  term and until  successors  of such
directors  are duly  elected  and  qualified.  Two Class III  directors  will be
elected at this year's Annual  Meeting.  The nominees for election to the office
of director,  and certain  information with respect to their backgrounds and the
backgrounds of non-nominee  directors,  are set forth below. It is the intention
of  the  persons  named  in  the  accompanying   proxy  card,  unless  otherwise
instructed,  to vote to elect the nominees  named herein as Class III directors.
Each of the nominees named herein presently serves as a director of the Company.
In the event any of the nominees  named herein is unable to serve as a director,
discretionary  authority  is  reserved to the Board of  Directors  to vote for a
substitute.  The Board of  Directors  has no reason to  believe  that any of the
nominees named herein will be unable to serve if elected.

                 Nominees for Election to the Office of Director
                           at the 1998 Annual Meeting

                                         Director
Nominee                     Age          Since       Position with the Company
- -------                     ---          -----       -------------------------

Rolf A. Classon(2)           53          1997        Director
                                     
Robert LeBuhn(2)(3)          66          1994        Director


                    Non-Nominee Directors Continuing to Serve
             in the Office of Director After the 1998 Annual Meeting

                                           Director
Nominee                           Age      Since       Position with the Company
- -------                           ---      -----       -------------------------

Peter G. Tombros(1)(4)            56       1994        President and Chief 
                                                       Executive Officer

Randy H. Thurman(1)(5)            49       1993        Chairman of the Board

Dr. Rosina B. Dixon(2)(4)         55       1994        Director

Dr. David W. Golde(5)             58       1998        Director

A.M. "Don" MacKinnon(1)(3)(5)     73       1990        Director


(1)  Member of the Executive Committee

(2)  Member of the Compensation Committee

(3)  Member of the Audit Committee

(4)  Class I  director  serving  until  the 1999  Annual  Meeting  

(5)  Class II director serving until the 2000 Annual Meeting


                                       2


<PAGE>


                        BUSINESS EXPERIENCE OF DIRECTORS

Nominee Class III Directors for Election at the 1998 Annual Meeting

     Rolf A. Classon has served as a Director of the Company since January 1997.
Mr. Classon is currently an Executive Vice  President of Bayer  Corporation  and
President of Bayer Diagnostics.  From 1991 to 1995, Mr. Classon was an Executive
Vice President in charge of Bayer Diagnostics'  Worldwide  Marketing,  Sales and
Service  operations.  From 1990 to 1991,  Mr.  Classon was  President  and Chief
Operating Officer of Pharmacia Biosystems A.B. Prior to 1991, Mr. Classon served
as president of Pharmacia  Development  Company Inc. and Pharmacia A.B. Hospital
Products Division.

     Robert  LeBuhn has served as a Director of the Company  since  August 1994.
Mr. LeBuhn was chairman of Investor  International (U.S.), Inc., a subsidiary of
Investor  A.B.,  part of  Sweden's  Wallenberg  Group  from June 1992  until his
retirement in September  1994,  and was its  president  from August 1984 through
June 1992.  Mr.  LeBuhn is a  director  of US Airways  Group,  Inc.,  Acceptance
Insurance Companies, Inc. and Cambrex Corporation. He is president and a trustee
of the Geraldine R. Dodge Foundation.

     The Board of Directors  recommends a vote FOR Mr. Classon and Mr. LeBuhn as
Class III Directors (Proposal No. 1 on the Proxy Card).

Non-Nominee Class I Directors Serving Until the 1999 Annual Meeting

     Peter G. Tombros has served as President and Chief Executive Officer of the
Company and a member of the board since April 1994.  Prior to joining Enzon, Mr.
Tombros  spent 25 years with Pfizer Inc., a research  based,  global  healthcare
company  headquartered in New York City. From 1986 to March 1994, he served as a
vice president of Pfizer Inc. in the following  areas:  executive vice president
of Pfizer  Pharmaceuticals,  a  division  of Pfizer  Inc.,  corporate  strategic
planning and investor relations. From 1980 to 1986, Mr. Tombros served as senior
vice  president  of Pfizer  Pharmaceuticals  and general  manager for the Roerig
division of Pfizer Inc. Mr. Tombros currently serves on the Board of Trustees of
Cancer Care and the National Cancer Care Foundation,  Dominican College and Fisk
University.  From 1980 to 1992, he was a director of the American  Foundation of
Pharmaceutical  Education  and served as Chairman for three of those years.  Mr.
Tombros  serves  on the  Board of  Directors  of NPS  Pharmaceuticals  Inc.  and
Alpharma Inc.

     Dr.  Rosina B. Dixon has served as a Director of the Company  since  August
1994. Dr. Dixon has been a consultant to the pharmaceutical industry since 1987.
Prior to such time she held senior  positions at Ciba-Geigy  Pharmaceuticals,  a
division  of  Ciba-Geigy  Corporation,   and  Schering-Plough  Corporation.  She
received her M.D. from Columbia  University,  College of Physicians and Surgeons
and is  certified by the National  Board of Medical  Examiners  and the American
Board of Internal Medicine.  She is a member of the American College of Clinical
Pharmacology,  American  Society for Clinical  Pharmacology and Therapeutics and
the  National  Association  of Corporate  Directors  and  currently  serves as a
director of Church & Dwight Co., Inc. and Cambrex Corporation.

Non-Nominee Class II Director Serving Until the 2000 Annual Meeting

     Randy H.  Thurman  has served as the  Chairman  of the Board of the Company
since April 1996 and as a Director of the Company since April 1993.  Mr. Thurman
is Chairman and Chief Executive Officer of Strategic Reserves, LLC, a company he
founded in 1996.  Mr.  Thurman is the founder and has been Chairman of the Board
of Health Care Strategies 2000, a global healthcare consulting firm, since 1995.
During 1996,  Mr. Thurman also served as a principal of Spencer Stuart Inc. From
1993 to 1995,  Mr.  Thurman  served as Chairman and Chief  Executive  Officer of
Corning  Life  Sciences.  From 1985 to 1993,  Mr.  Thurman  served as  Corporate
Executive  Vice  President  and a Director  of  Rhone-Poulenc  Rorer,  Inc.  and
President of  Rhone-Poulenc  Rorer  Pharmaceuticals,  Inc. He also serves on the
Board of Directors of Closure Medical, Inc.


                                       3

<PAGE>


     A.M.  "Don"  MacKinnon  has served as a Director of the Company since 1990.
Mr.   MacKinnon  was  president  and  chief  operating   officer  of  Ciba-Geigy
Corporation from 1980 until his retirement in 1986. He was a member of the Board
of Directors of Ciba-Geigy  Corporation from 1970 until he reached the mandatory
retirement age in December  1994.  Over the last nine years,  Mr.  MacKinnon has
served on the Board of Directors of several biopharmaceutical companies.

     Dr.  David W. Golde has served as a Director  of the  Company  since  March
1998.  Dr.  Golde has been the  Physician-In-Chief  at Memorial  Sloan-Kettering
Cancer  Center  since 1996.  From 1991 to 1996,  Dr. Golde served as Head of the
Division of Hematology and Oncology at Memorial  Sloan-Kettering  Cancer Center.
Prior to 1991,  Dr.  Golde was a professor of medicine and Chief of the Division
of  Hematology  and  Oncology  at UCLA,  Director  of the UCLA AIDS  Center  and
Director of the UCLA Clinical Research Center.

                             DIRECTORS' COMPENSATION

Directors' Cash Compensation

     During the  fiscal  year ended June 30,  1998,  the  Company  paid Randy H.
Thurman  $100,000 in  consideration  for  serving as Chairman of the Board.  The
Company did not pay cash  compensation to its remaining  directors for acting as
directors  or as members of  committees  of the Board of  Directors,  other than
reimbursement  of  reasonable  expenses  incurred by the  directors in attending
board and committee meetings.

Directors' Stock Options

     In December  1993,  the Board of Directors  adopted,  and the  stockholders
approved,  an amendment to the Non-Qualified Stock Option Plan, as amended, (the
"Plan") providing for automatic grants of options  ("Automatic  Grants") under a
formula  (the  "Formula")  to  non-executive  members of the Board of  Directors
("Independent Directors").

     Under the Formula, Independent Directors automatically receive an option to
purchase 60,000 shares of Common Stock on each of the following  dates:  January
2,  1994,  January 2, 1997,  January 2, 2000 and  January 2, 2003 (the  "Regular
Grants").  On the date of each  Independent  Director's  initial election to the
board,  pursuant  to a vote of the  Company's  stockholders  or the board,  such
newly-elected  Independent  Director  automatically  receives  (i) an  option to
purchase such Independent  Director's pro rata share of the Regular Grant, which
equals the product of 1,666  multiplied by the number of whole months  remaining
in the relevant  three year period  until the next Regular  Grant (the "Pro Rata
Grant");  and (ii) an option to  purchase  10,000  shares of Common  Stock  (the
"Initial  Election  Grant").  Each  option  granted to an  Independent  Director
pursuant  to a Regular  Grant vests and becomes  exercisable  as follows:  as to
20,000  shares one year after the date of grant;  as to 20,000  shares two years
after the date of grant, and as to the remaining 20,000 shares three years after
the date of grant.  Those options granted  pursuant to a Pro Rata Grant vest and
become  exercisable  as to that  number of shares  equal to the product of 1,666
multiplied by the number of whole months remaining in the first calendar year in
which the Independent  Director is elected initially to the board on the January
1st following such Independent  Director's initial election to the board; and as
to any  remaining  shares in  accordance  with the schedule for options  granted
pursuant  to a Regular  Grant.  Those  options  granted  pursuant  to an Initial
Election Grant vest and become exercisable as to 5,000 shares one year after the
date of grant; and as to 5,000 shares two years after the date of grant. The per
share exercise price of options granted  pursuant to the Formula is equal to the
fair market value of the Common Stock on the date of grant.

     An option granted to an Independent  Director  pursuant to the Formula will
not  become  exercisable  as to the  relevant  shares  unless  such  Independent
Director has served continuously on the board during the year preceding the date
on which such options are scheduled to vest and become exercisable,  or from the
date such  Independent  Director  joined  the  board  until the end of such year
should  such  Independent  Director  have  joined  the board  during  such year;
provided,  however,  that if an  Independent  Director  does  not  fulfill  such
continuous  service  requirement  due to such  Independent  Director's  death or
disability  all options  granted under the Formula and held by such  Independent
Director  nonetheless  vest and become  exercisable  as though such  Independent
Director fulfilled the continuous


                                       4

<PAGE>


service  requirement.  An option granted to an Independent  Director pursuant to
the  Formula  remains  exercisable  for a period of ten  years  from the date of
grant.  For a discussion of proposed  amendments to the Plan,  which will affect
options granted to Independent Directors, see Proposal No. 2

Independent Directors' Stock Plan

     The Company's  1996  Independent  Directors'  Stock Plan (the  "Independent
Directors' Stock Plan") provides  compensation to Independent  Directors serving
on the board which is paid in the form of the Company's Common Stock. Other than
the Chairman of the Board,  Independent  Directors are not currently entitled to
receive cash  compensation.  Under the Independent  Directors'  Stock Plan, each
Independent Director is entitled to compensation in the form of shares of common
stock of the Company  with a value equal to $2,500 per quarter and $500 for each
meeting attended by the board member.  The number of shares issued will be based
on the  last  reported  sale  price  of a share of  Common  Stock on the  NASDAQ
National Market at the end of the quarter for which fees are payable. During the
year ended June 30, 1998, the Company recorded $71,834 in Independent Directors'
fees.  The  following  is a  summary  of  compensation  paid to the  Independent
Directors under the Independent Director's Stock Plan:

                                               Value of             Number
                                            Consideration          of Shares
                                            -------------          ---------
        Randy H. Thurman                      $13,500                2,325
        Rolf A. Classon                        12,000                2,058
        Dr. Rosina Dixon                       14,000                2,404
        David W. Golde                          4,334                  672
        Robert LeBuhn                          14,000                2,404
        A.M. "Don" MacKinnon                   14,000                2,404
                                                              

Section 16(a) Beneficial Ownership Reporting Compliance

     Ownership of and transactions in the Company's stock by executive  officers
and  directors  of the  Company  and  owners  of 10% or  more  of the  Company's
outstanding  Common  Stock are  required to be reported  to the  Securities  and
Exchange  Commission pursuant to Section 16(a) of the Securities Exchange Act of
1934,  as amended.  During the year ended June 30,  1998,  all such reports were
filed in a timely manner.

               INFORMATION CONCERNING BOARD AND COMMITTEE MEETINGS
                           AND COMMITTEES OF THE BOARD

     Eight  meetings of the  Company's  Board of Directors  were held during the
fiscal year ended June 30,  1998.  Rolf A.  Classon  attended  four of the eight
Board of  Directors  meetings  held.  With the  exception of Mr.  Classon,  each
incumbent  director attended at least 75% of the total number of meetings of the
Board of Directors.  All incumbent  directors attended at least 75% of the total
number of meetings of any  committees of the Board of  Directors,  of which such
director was a member, held during the fiscal year.

     As of June 30, 1998, the only standing committees of the Company's Board of
Directors  were  the  Audit  Committee,  Compensation  Committee  and  Executive
Committee.

     The Audit Committee is comprised of Robert LeBuhn, Chairman, and A.M. "Don"
MacKinnon.  The primary  functions of the Audit  Committee  are to meet with the
Company's  independent  auditors  to discuss  and review  audit  procedures  and
issues,  meet with  management on matters  concerning  the  Company's  financial
condition,  internal controls and year-end audit and report to the board on such
matters. The Audit Committee held two meetings during the fiscal year ended June
30, 1998.


                                       5
<PAGE>


     The   Compensation   Committee  is  comprised  of  Dr.   Rosina  B.  Dixon,
Chairperson,  Rolf A. Classon and Robert  LeBuhn.  The primary  functions of the
Compensation  Committee are to  administer  the  Company's  Non-Qualified  Stock
Option Plan,  determine the  compensation  of the Company's  officers and senior
management  and review  compensation  policy.  There were four  meetings  of the
Compensation Committee during the fiscal year ended June 30, 1998.

     The Executive Committee, comprised of A.M. "Don" MacKinnon, Chairman, Peter
G. Tombros,  and Randy H. Thurman,  was established to review and make decisions
concerning  matters which would otherwise come before the Board, as permitted by
Delaware General Corporate Law and the Company's  by-laws.  Given the relatively
small size of the Company's current Board of Directors,  the Company  determined
that  efficiencies  were not  being  realized  from  meetings  of the  Executive
Committee and therefore suspended regular meetings of the Executive Committee in
September  1994.  There were no meetings of the Executive  Committee  during the
fiscal year ended June 30, 1998.

                      COMPENSATION COMMITTEE INTERLOCKS AND
                              INSIDER PARTICIPATION

     As of the date hereof, the members of the Board of Directors serving on the
Compensation  Committee  of the Board of  Directors  are Dr.  Rosina  B.  Dixon,
Chairperson, Dr. Rolf A. Classon and Robert LeBuhn, all of whom are non-employee
directors of the Company.

                    BUSINESS EXPERIENCE OF EXECUTIVE OFFICERS

     Set forth below is certain information  regarding the executive officers of
the Company who do not serve on the Board of Directors.

     John A. Caruso, 53, has served as Vice President,  Administration since May
1998,  General  Counsel of the Company  since July 1994 and as  Secretary of the
Company  since July 1989.  From January 1991 to May 1998,  Mr.  Caruso served as
Vice  President of Business  Development.  From  January 1991 to July 1994,  Mr.
Caruso served as Vice President,  Legal Affairs of the Company. From the time he
joined the Company in September 1987 through December 1990, Mr. Caruso served as
Corporate  Counsel  to the  Company.  From 1979  through  1987,  Mr.  Caruso was
employed at Baxter  Travenol  Laboratories  in Deerfield,  Illinois as corporate
counsel.

     Kenneth  J.  Zuerblis,  39,  has served as Chief  Financial  Officer  since
January 1996 and as Vice President,  Finance since April 1994. From July 1991 to
April 1994, Mr. Zuerblis served as the Company's  Controller.  From January 1982
to July 1991,  Mr.  Zuerblis  was employed by KPMG Peat Marwick LLP. He became a
certified public accountant in 1985.


                                       6

<PAGE>


                           SUMMARY COMPENSATION TABLE

         The   following   table   provides  a  summary  of  cash  and  non-cash
compensation  for each of the last three fiscal years ended June 30, 1998,  1997
and 1996 with respect to Enzon's Chief Executive Officer and the other executive
officers  serving  during  the  fiscal  year  ended  June 30,  1998 (the  "Named
Executive Officers").

<TABLE>
<CAPTION>
                                                                                                  
                                             Annual Compensation                                  Long-Term
                                     -------------------------------                             Compensation
                                                                                                    Awards 
                                                                                                 -----------
                                                                                                  Securities
        Name and                                                           Other Annual           Underlying          All Other
   Principal Position                Year     Salary($)     Bonus($)    Compensation($)(1)        Options(#)      Compensation($)(2)
   ------------------                ----     ---------     --------    ------------------        ----------      ------------------
<S>                                  <C>      <C>          <C>              <C>                   <C>                 <C>
Peter G. Tombros                     1998     $336,000     $ 70,560         $   --                 78,000(5)          $  5,000
President and Chief                  1997      307,626       50,000(4)          --                420,000                4,729
  Executive Officer                  1996      300,000         --             36,000(3)            60,000                  950
                                                                                                                     
John A. Caruso                       1998      171,642     $ 26,025             --                 90,000(5)              --
Vice President, Administration,      1997      170,000       25,000             --                 80,000                  163
  General Counsel and Secretary      1996      163,651       39,100             --                 40,000                 --
                                                                                                                     
Kenneth J. Zuerblis                  1998      154,692     $ 33,600             --                110,000(5)             3,775
Vice President, Finance and          1997      148,052       40,000             --                 90,000                5,395
   Chief Financial Officer           1996      132,813       24,871             --                 40,000                1,989
</TABLE>                                                                        
                                                                                

(1)  Excludes  perquisites and other personal  benefits that in the aggregate do
     not exceed 10% of the Named  Executive  Officer's  total annual  salary and
     bonus.

(2)  Consists of annual Company contributions to a 401(k) plan.

(3)  Consists  of auto and living  allowance.  As of April 5, 1997,  the Company
     ceased paying Mr. Tombros an auto and living allowance.

(4)  The payment of Mr. Tombros' bonus, earned for the year ended June 30, 1997,
     was deferred at his option.  

(5)  Includes stock options granted during July 1998,  which represent a portion
     of the Named Executive Officer's total bonus earned for the year ended June
     30, 1998.


                                       7


<PAGE>


                        OPTION GRANTS IN LAST FISCAL YEAR

     The following  table  contains  information  concerning  the grant of stock
options  under  the  Company's  Non-Qualified  Stock  Option  Plan to the  Named
Executive Officers during the fiscal year ended June 30, 1998.

<TABLE>
<CAPTION>
                                            Individual Grants  
                           ------------------------------------------------
                           Number of                                                         Potential Realizable Value at Assumed
                           Securities      % of Total                                              Annual Rates of Stock Price    
                           Underlying    Options Granted                                        Appreciation  for Option Term (3) 
                            Options        to Employees    Exercise or Base   Expiration      ------------------------------------
Name                       Granted (1)    in Fiscal Year     Price ($/Share)     Date         0%($)          5%($)          10%($) 
- ----                       -----------    --------------     ---------------     ----         -----          -----          ------ 
<S>                         <C>                <C>              <C>             <C>            <C>          <C>           <C>     
John A. Caruso              40,000(2)          7.07%            $6.00           12/02/07       0            $150,935      $382,498
                                                                                                                         
Kenneth J. Zuerblis         40,000(2)          7.07%             6.00           12/02/07       0             150,935       382,498
</TABLE>


(1)  All options were granted at an exercise  price that equaled or exceeded the
     fair market value of the Common Stock on the date of grant,  as  determined
     by the last sale price as  reported  on the  NASDAQ  National  Market.  The
     options will become exercisable as to all shares immediately upon a "change
     in  control" of the  Company as defined in certain  agreements  between the
     executive  officers  and  the  Company.  See  "Employment  and  Termination
     Agreements".

(2)  These  options  will vest and  become  exercisable  as to 50% of the shares
     granted on December 2, 1998 and 50% on December 2, 1999,  provided that the
     Named Executive Officer is employed by the Company on the vesting date.

(3)  The amounts set forth in the three  columns  represent  hypothetical  gains
     that might be  achieved  by the  optionees  if the  respective  options are
     exercised at the end of their terms. These gains are based on assumed rates
     of stock price appreciation of 0%, 5% and 10% compounded  annually from the
     dates the respective  options were granted.  The 0% appreciation  column is
     included  because the options  were  granted  with  exercise  prices  which
     equaled or exceeded the market price of the underlying  Common Stock on the
     date of grant, and thus will have no value unless the Company's stock price
     increases above the exercise prices.


                                       8


<PAGE>


                   OPTION EXERCISES AND FISCAL YEAR-END VALUES

     The following  table sets forth the  information  with respect to the Named
Executive  Officers  concerning  the exercise of options  during the fiscal year
ended June 30, 1998 and unexercised options held as of June 30, 1998.

<TABLE>
<CAPTION>
                                                                    Number of Securities           Value of Unexercised   
                                                                  Underlying Unexercised           In-the-Money Options   
                                                                   Options at FY-End (#)              at FY-End ($)(1)     
                           Shares Acquired     Value          -----------------------------   ------------------------------
  Name                     On Exercise (#)   Realized($)      Exercisable     Unexercisable   Exercisable      Unexercisable
  ----                     ----------------  -----------      -----------     -------------   -----------      -------------
<S>                            <C>          <C>                 <C>              <C>           <C>                <C>    
Peter G. Tombros                 --         $     --            909,000          160,000       $2,669,063         $590,000

John A. Caruso                 30,000          117,813          190,992           80,000          565,813          162,500

Kenneth J. Zuerblis            30,000          117,813          165,000           85,000          499,375          180,313
</TABLE>

(1)  Based upon a market value of $6.38 as  determined by the last sale price as
     reported on the NASDAQ  National  Market on June 30, 1998.  If the exercise
     price is equal to or  greater  than  such last sale  price,  the  option is
     deemed to have no value.

                      EMPLOYMENT AND TERMINATION AGREEMENTS

     The Company has a three-year  employment agreement with Mr. Tombros,  which
terminates in April 2000, pursuant to which he receives an annual base salary of
$336,000.  In the event Mr.  Tombros'  employment is terminated  for any reason,
except if such  employment is terminated  (i)  voluntarily by Mr. Tombros (other
than in  response  to the  Company's  prior  material  breach of the  employment
agreement),  (ii) by the  Company  "for  cause" (as  defined  in the  employment
agreement) or (iii) as a result of Mr. Tombros' death or disability, Mr. Tombros
will be entitled to receive his base salary for one year after such termination.
In the  event  Mr.  Tombros'  employment  is  terminated  due to  his  death  or
disability  his base  salary  will be paid  for six  months  subsequent  to such
termination.  Pursuant to his  employment  agreement,  Mr. Tombros was granted a
ten-year option under the Company's  Non-Qualified Stock Option Plan to purchase
300,000  shares of the Company's  Common Stock at a per share  exercise price of
$2.69, the fair market value of the Company's Common Stock on the date of grant.
The vesting and  exercisability  of the options  granted  accelerated in 100,000
share  increments  when the closing stock price of the  Company's  common stock,
exceeded $4, $5 and $6 per share, for at least twenty  consecutive  trading days
as reported by the NASDAQ National  Market.  Mr. Tombros'  employment  agreement
also requires him to maintain the  confidentiality  of Company  information  and
assign  inventions to the Company.  Mr. Tombros is precluded from competing with
the Company during the term of his employment  agreement and for two years after
his  employment is terminated if his employment is terminated by the Company for
cause or by Mr. Tombros  voluntarily  (except in response to the Company's prior
material breach of the employment agreement).

     The  Company  has  agreements  with each of its  executive  officers  which
provide for payment to each executive officer of three years of compensation and
benefits  (as defined in such  agreements)  following a change in control of the
Company  (as  defined in such  agreements),  including  the  provision  for such
payment in the event such  executive  officer's  employment  with the Company is
terminated under certain circumstances  following such change in control. Upon a
change in control of the Company,  all options held by such  executive  officers
shall vest  immediately,  notwithstanding  any vesting  provisions in the option
certificates or any plan covering such options.  The term of these agreements is
for three  years.  Prior to a change in control of the Company,  the  agreements
automatically  renew on each  successive  anniversary  for an  additional  three
years,  unless the Company gives the  executive  officer 60 days notice prior to
the anniversary date that it does not plan to renew such contracts.



                                       9
<PAGE>

         REPORT OF THE COMPENSATION COMMITTEE OF THE BOARD OF DIRECTORS

     The  Compensation  Committee  of the Board of  Directors  consists of three
non-employee  directors and determines all  compensation  paid or awarded to the
Company's  executive  officers,  including the Named  Executive  Officers in the
Summary Compensation Table. As with many other biotechnology companies,  Enzon's
current level of development  and the highly  volatile  nature of  biotechnology
stocks  in  general  makes  executive  compensation  which is based on sales and
earnings goals or stock performance  impracticable.  The Compensation  Committee
believes  that  an  important   factor  in  Enzon's  success  is  the  continued
development and maintenance of a culture focused on  team-oriented  performance.
In this context, compensation has been based on the accomplishment of a blend of
mutually shared and individual  goals. The  Compensation  Committee has reviewed
the executive  compensation  of other  biotechnology  companies with  comparable
levels of  stockholders'  equity and  development and has designed the Company's
total  executive  compensation  to  be  targeted  at  the  median  of  executive
compensation  levels  of these  companies.  The  compensation  of the  Company's
executive  officers consist of three principal  components:  (i) base salary and
benefits,  (ii) a bonus  based on  individual  contributions  evaluated  against
annual goals and (iii) long-term incentives in the form of stock option grants.

     For the  fiscal  year  ended  June 30,  1998,  the  Compensation  Committee
instituted a formal Performance Incentive Program for its executive officers and
other members of senior management.  The structure and design of the program was
based on a  detailed  study of  compensation  programs  provided  at  comparable
biotechnology companies. Under the program, Mr. Tombros can earn a cash bonus of
up to a maximum of 35% of his base salary and  receive  stock  option  grants to
purchase Common Stock of up to a maximum of 130,000 shares.  The other executive
officers,  Mr.  Caruso and Mr.  Zuerblis,  can each earn a cash bonus of up to a
maximum of 30% of their base salary and stock option  grants to purchase  Common
Stock of up to a maximum of 100,000 shares of Common Stock.  The amount of bonus
paid  and  options  granted  under  the plan is based  upon the  achievement  of
predetermined  corporate and individual objectives.  Stock options granted under
the plan are granted with exercise  prices equal to the fair market value of the
Company's Common Stock on the date of grant.

     The  annual  salary of  $336,000  and the bonus  awarded  to the  Company's
President  and Chief  Executive  Officer for the fiscal year ended June 30, 1998
were based on Mr. Tombros' extensive prior experience as a senior executive of a
major  multinational  pharmaceutical  firm  and the  compensation  paid to chief
executive officers with similar credentials at comparable biotech companies. The
bonus paid to Mr. Tombros under the Company's  Performance Incentive Program was
based on many factors  including the  strengthening  of the Company's  financial
position, increasing the awareness of the Company to the financial community, as
well as the  progress  made by the Company  and its  partners on products in the
Company's development pipeline.

     During the fiscal  year ended June 30,  1998,  the  Compensation  Committee
awarded cash  bonuses  under the plan  described  above to the  Company's  other
executive officers,  Messrs. Caruso and Zuerblis.  The bonuses were based on the
executives'   contributions  to  the  improvement  of  the  Company's  financial
position.  The Company  also  adjusted  the salary  level of Mr.  Caruso and Mr.
Zuerblis.  The salary adjustments were based on a detailed compensation study of
executives with similar credentials at comparable biotechnology companies.

     In addition to the option granted under the Performance  Incentive Program,
described  above,  during the fiscal year ended June 30, 1998, the  Compensation
Committee  granted  options to purchase an aggregate of 80,000  shares of Common
Stock to Messrs. Caruso and Zuerblis. These options were granted for the purpose
of  encouraging  these  executive  officers  to remain  with the  Company and to
provide a long-term  performance  incentive to such  officers.  The options were
granted with  exercise  prices that equaled or exceeded the fair market value of
the Company's Common Stock on the date of grant. The options  generally  require
the executive officers to remain with the Company for two years in order for the
options to be fully exercisable.

                                                THE COMPENSATION COMMITTEE

                                                Dr. Rosina B. Dixon, Chairperson
                                                Rolf A. Classon
                                                Robert LeBuhn


                                       10
<PAGE>

                      STOCKHOLDER RETURN PERFORMANCE GRAPH

     The graph below summarizes the total cumulative  return  experienced by the
Company's stockholders from June 30, 1993 through June 30, 1998, compared to the
NASDAQ  National  Market  Index  and a Peer  Group  index  consisting  of:  Isis
Pharmaceuticals,  Inc., Repligen Corp.,  Celgene Corp.,  Gensia  Pharmaceuticals
Inc.,  Collagen Corp.,  Liposome Inc., Cytel Corp.,  Cytogen Corp., DNAP Holding
Corp.,  (formerly  DNA Plant  Technology  Corp.) and  Cephalon  Inc.  (the "Peer
Group").   The  Company  and  the  companies   comprising  the  Peer  Group  are
biotechnology  companies which are all traded on the NASDAQ National Market. The
Peer Group used for the stockholder  return  performance  graph does not include
Synergen  Inc.,  Cambridge  Biotech  Corporation,  or Calgene,  Inc.  which were
included in the Peer Group in prior years. Synergen Inc., and Calgene, Inc. were
acquired and are no longer publicly traded.  Cambridge Biotech Corporation is no
longer traded on the NASDAQ National  Market.  The changes for the periods shown
in the  graph and table  below  are based on the  assumption  that $100 had been
invested in Enzon, Inc. Common Stock and in each index below on June 30, 1993.

                 COMPARISON OF FIVE YEAR CUMULATIVE TOTAL RETURN
     AMONG ENZON, INC., THE NASDAQ NATIONAL MARKET-US INDEX AND A PEER GROUP


 [THE FOLLOWING TABLE WAS REPRESENTED BY A LINE CHART IN THE PRINTED MATERIAL.]


                                           Fiscal year ending June 30,
                                ------------------------------------------------
                                1993     1994    1995     1996     1997     1998
                                ----     ----    ----     ----     ----     ----

Enzon, Inc.                     100       56       49       72       46      131
Peer Group                      100       58       71       96       60       47
NASDAQ  Stock
  Market-US                     100      101      135      173      210      278



                                       11
<PAGE>


                          SECURITY OWNERSHIP OF CERTAIN
                        BENEFICIAL OWNERS AND MANAGEMENT

         The following  table sets forth certain  information  concerning  stock
ownership of all persons known by the Company to own  beneficially 5% or more of
the  outstanding  shares of the Company's  voting  stock,  each  Director,  each
Executive  Officer  named in the Summary  Compensation  Table and all  Executive
Officers and Directors of the Company as a group as of October 19, 1998:


<TABLE>
<CAPTION>
                                                                        Percentage of
Directors, Officers or                         Number of                 Voting Stock
  5% Stockholders(1)                           Shares(2)                Outstanding(3)
  ------------------                           ---------                --------------
<S>                                          <C>                             <C> 
Peter G. Tombros                             1,066,300 (4)                   2.9%
Randy H. Thurman                               224,937 (5)                     *
Rolf A. Classon                                 30,175 (6)                     *
Dr. Rosina B. Dixon                            101,680 (7)                     *
Dr. David W. Golde                             110,272 (8)                     *
Robert LeBuhn                                  106,798 (9)                     *
A.M. "Don" MacKinnon                           161,616(10)                     *
John A. Caruso                                 231,292(11)                     *
Kenneth J. Zuerblis                            211,600(12)                     *
Clearwater Fund IV Ltd.                      2,832,831(13)                   7.9%
  P.O. Box 662
  Tortola, British Virgin Islands
State of Wisconsin                           2,521,000(14)                   7.1%
  Investment Board
  P.O. Box 7842
  Madison, Wisconsin 53707
All Executive Officers and Directors         2,244,670(15)                   5.9%
 as a group (nine persons)
</TABLE>

- ----------
*    Less than one percent.

(1)  The address of all current Executive Officers and Directors listed above is
     in the care of the Company.

(2)  All shares  listed are Common  Stock.  Except as discussed  below,  none of
     these  shares are  subject to rights to acquire  beneficial  ownership,  as
     specified in Rule 13d-3(d)(1) under the Securities Exchange Act of 1934, as
     amended,  and the beneficial  owner has sole voting and  investment  power,
     subject to community property laws where applicable.

(3)  Gives effect to  35,409,969  shares of Common  Stock and 108,000  shares of
     Series A Preferred  Stock which were issued and  outstanding  as of October
     19,  1998.  Generally,  the Series A Preferred  Stock and Common Stock will
     vote as one class of stock.  Each  share of Common  Stock and each share of
     Series A Preferred  Stock is entitled to one vote. The percentage of voting
     stock  outstanding  for each  stockholder is calculated by dividing (i) the
     number of shares deemed to be beneficially  held by such  stockholder as of
     October  19,  1998 by (ii) the sum of (A) the  number  of  shares of Common
     Stock  outstanding  as of October 19, 1998 plus (B) the number of shares of
     Series A Preferred  Stock  outstanding  as of October 19, 1998 plus (C) the
     number of shares issuable upon exercise of options or warrants held by such
     stockholder  which were  exercisable  as of October  19, 1998 or which will
     become exercisable within 60 days after October 19, 1998.

(4)  Includes  1,039,000  shares subject to options which were exercisable as of
     October  19,  1998 or which will  become  exercisable  within 60 days after
     October 19, 1998.


                                       12
<PAGE>


(5)  Consists of 200,000 shares subject to options which were  exercisable as of
     October  19,  1998 or which will  become  exercisable  within 60 days after
     October 19, 1998.

(6)  Includes  25,000  shares  subject to option  which were  exercisable  as of
     October  19,  1998 or which will  become  exercisable  within 60 days after
     October 19, 1998.

(7)  Includes  76,664  shares  subject to options which were  exercisable  as of
     October  19,  1998 or which will  become  exercisable  within 60 days after
     October 19, 1998.

(8)  Includes  72,800  shares  held by a separate  corporation  for Dr.  Golde's
     retirement,  2,800  shares held by three  separate  trusts for Dr.  Golde's
     children and 1,000 shares beneficially owned by Dr. Golde's wife.

(9)  Includes  76,664  shares  subject to options which were  exercisable  as of
     October  19,  1998 or which will  become  exercisable  within 60 days after
     October 19, 1998.

(10) Includes  132,000  shares  subject to options which were  exercisable as of
     October  19,  1998 or which will  become  exercisable  within 60 days after
     October 19, 1998 and 11,800 shares  beneficially  owned by Mr.  MacKinnon's
     wife. Mr. MacKinnon disclaims  beneficial  ownership as to the shares owned
     by his wife.

(11) Consists of 230,992 shares subject to options which were  exercisable as of
     October  19,  1998 or which will  become  exercisable  within 60 days after
     October 19, 1998.

(12) Includes  210,000  shares  subject to options which were  exercisable as of
     October  19,  1998 or which will  become  exercisable  within 60 days after
     October 19, 1998 and 600 shares owned by Mr. Zuerblis' IRA.

(13) Includes  warrants to purchase 273,723 shares of the Company's Common Stock
     at $4.11 per share and  warrants  to purchase  200,000  shares at $5.63 per
     share.  The  information  concerning the Stock  ownership of the Clearwater
     Fund IV Ltd. was obtained from a schedule 13D filed with the Securities and
     Exchange Commission dated February 28, 1997.

(14) The  information  concerning the stock  ownership of the State of Wisconsin
     Investment  Board was  obtained  from a schedule  13F filed by the State of
     Wisconsin  Investment Board with the Securities and Exchange Commission for
     the period ended June 30, 1998.

(15) Includes all shares  owned  beneficially  by the  directors  and  executive
     officers named in the Summary Compensation table.



                                       13
<PAGE>


                     PROPOSAL NO. 2 - APPROVAL OF AMENDMENT
                     TO THE NON-QUALIFIED STOCK OPTION PLAN

     In  November   1987,   the  Company's   Board  of  Directors   adopted  the
Non-Qualified  Stock  Option Plan (the "Plan") in order to enable the Company to
attract and retain qualified employees,  directors and independent  consultants.
Subject  to  stockholder  approval,  the  Board of  Directors  has  approved  an
amendment to the Plan to reflect changes described below.

     The following summary  description of the Plan is qualified in its entirety
by the full text of the Plan which may be obtained by the Company's stockholders
upon request to the Secretary of the Company.

     The last sale price of a share of the Company's Common Stock as reported by
the NASDAQ National Market on October 19, 1998 was $6.00.

Basic Terms

     Under the Plan,  directors,  officers  and  employees  of the  Company  and
independent  consultants  to the Company  have been,  and will be,  eligible for
grants of options to  purchase  shares of Common  Stock.  To date,  all  options
granted  under the Plan  have been  awarded  at the  discretion  of the Board of
Directors or a committee  thereof or pursuant to the formulas  described  below.
Currently,  the Compensation  Committee of the Board of Directors determines who
will receive  options under the Plan, the number of shares of Common Stock which
will be issuable  upon  exercise of options which are granted under the Plan and
the terms of the options  granted under the Plan to the extent the terms are not
otherwise set forth in the Plan. Currently, no option granted under the Plan may
be  transferred  by the optionee,  otherwise than by will or the laws of descent
and distribution and, generally,  during the optionee's lifetime, the option may
be exercised only by the optionee.  The exercise price of the options must be at
least equal to the fair market  value of the  underlying  Common Stock as of the
date of grant.  Either the  Compensation  Committee of the Board of Directors or
the Board of Directors may, in its discretion, provide that an option may not be
exercised in whole or in part for any  specified  period or periods of time.  No
option  may be  exercised  prior to six  months  from  the date of grant  except
immediately  prior to the  dissolution or liquidation of the Company or a merger
or consolidation  where the Company is not the surviving  corporation,  in which
case all outstanding options become immediately  exercisable.  Options expire no
later than the tenth anniversary of the date of grant.

Automatic Awards To Independent Directors

     The Plan provides that Independent Directors receive option grants pursuant
to a formula (the  "Formula").  The Formula  provides that on each of January 2,
1994,  January  2,  1997,  January  2, 2000 and  January  2,  2003,  each of the
Company's Independent Directors will automatically receive an option to purchase
60,000  shares  of  Common  Stock  (the  "Regular  Grant").  On the date of each
Independent  Director's initial election to the board, pursuant to a vote of the
Company's  stockholders or the board, such  newly-elected  Independent  Director
will automatically receive (i) an option to purchase such Independent Director's
pro rata share of the  Regular  Grant,  which  will  equal the  product of 1,666
multiplied  by the number of whole months  remaining in the relevant  three year
period until the next Regular Grant (the "Pro Rata  Grant");  and (ii) an option
to purchase 10,000 shares of Common Stock (the "Initial Election  Grant").  Each
option granted to an Independent  Director pursuant to the Formula will vest and
become exercisable as follows: those options granted pursuant to a Regular Grant
will vest and become  exercisable as to 20,000 shares one year after the date of
grant;  as to 20,000  shares  two years  after the date of grant;  and as to the
remaining  20,000  shares  three  years after the date of grant.  Those  options
granted pursuant to a Pro Rata Grant will vest and become exercisable as to that
number of shares equal to the product of 1,666 multiplied by the number of whole
months remaining in the first calendar year in which the Independent Director is
elected  initially to the board on the January 1st  following  such  Independent
Director's  initial  election to the board;  and as to any  remaining  shares in
accordance  with the schedule for options  granted  pursuant to a Regular Grant.
Those options granted pursuant to an Initial Election Grant will vest and become
exercisable as to 5,000 shares one year after the date of grant; and as to 5,000
shares two years after the date of grant.


                                       14
<PAGE>


     An option granted to an Independent  Director  pursuant to the Formula will
not  become  exercisable  as to the  relevant  shares  unless  such  Independent
Director has served continuously on the board during the year preceding the date
on which such options are scheduled to vest and become exercisable,  or from the
date such  Independent  Director  joined  the  board  until the end of such year
should  such  Independent  Director  have  joined  the board  during  such year;
provided,  however,  that if an  Independent  Director  does  not  fulfill  such
continuous  service  requirement  due to such  Independent  Director's  death or
disability,  all options granted under the Formula and held by such  Independent
Director  shall   nonetheless  vest  and  become   exercisable  as  though  such
Independent  Director  fulfilled the continuous service  requirement.  An option
granted  to  an  Independent  Director  pursuant  to  the  Formula  will  remain
exercisable for a period of ten years from the date of grant.

Administration

     The Plan is to be  administered  by  either  the  Board of  Directors  or a
committee  of at  least  two  directors  appointed  by the  board.  The  Plan is
currently administered by the Compensation Committee.

Amendments and Termination

     Currently,  no options may be granted  under the Plan beyond  November  21,
2007. The Compensation Committee or the Board of Directors may terminate, amend,
or revise the Plan with respect to any shares as to which  options have not been
granted, but may not alter any previously granted options without the optionee's
consent.  Termination of the Plan will not affect  previously  granted  options.
Subject to the foregoing  restriction relating to outstanding options, the Board
can amend the Plan without stockholder  approval unless stockholder  approval is
required by applicable law or the rules of Nasdaq or any stock exchange on which
the Company's shares are then traded.

Capital Adjustments

     The aggregate  number of shares of Common Stock available for options,  the
shares  subject  to  any  option,   and  the  price  per  share,   will  all  be
proportionately  adjusted  for any  increase or decrease in the number of issued
shares of Common Stock  resulting  from (1) a subdivision  or  consolidation  of
shares or any other capital  adjustment,  (2) the payment of a stock dividend on
the  Company's  Common Stock,  or (3) other  increase or decrease in such shares
effected without receipt of  consideration by the Company.  If the Company shall
be the  surviving  corporation  in  any  merger  or  consolidation,  any  option
outstanding under the Plan shall pertain, apply, and relate to the securities to
which a holder of the  number of shares of Common  Stock  subject  to the option
would have been entitled after the merger or consolidation.  Upon dissolution or
liquidation  of the  Company,  or upon a merger  or  consolidation  in which the
Company is not the surviving corporation, all options outstanding under the Plan
shall  terminate;  except that each optionee  shall have the right,  immediately
prior to such dissolution or liquidation,  or such merger or  consolidation,  to
exercise the options that such optionee holds in whole or in part.

Tax Consequences

     An  optionee  will not  recognize  taxable  income for  Federal  income tax
purposes upon the receipt of an option under the Plan,  and the Company will not
be  entitled  to a deduction  upon the grant of an option.  Upon  exercise of an
option,  the optionee will recognize  ordinary income equal to the excess of the
fair  market  value on the date of exercise of the Common  Stock  received  upon
exercise  over the  exercise  price for such  Common  Stock.  However,  any such
optionee  who is subject to the  trading  restrictions  of Section  16(b) of the
Exchange Act would,  unless the optionee elected to recognize ordinary income on
the  date of  exercise,  recognize  ordinary  income  on the date  such  trading
restrictions  terminate (the "Deferred  Date").  The amount of such income would
equal the excess of the fair  market  value on the  Deferred  Date of the Common
Stock  received  upon  exercise of the option over the  exercise  price for such
Common Stock, and the holding period for long-term  capital gain treatment would
not begin until the Deferred  Date.  The Company will be entitled to a deduction
equal to the amount of ordinary  income  recognized  by any optionee at the same
time that such optionee recognized such income.


                                       15
<PAGE>


Eligible Participants

     As of October 19, 1998,  there were  approximately  100 persons eligible to
participate  in the Plan. Of these eligible  participants,  seven are members of
the Board of Directors (six of whom are Independent Directors),  six are members
of the Company's  Scientific  Advisory Board who are not board members,  two are
executive  officers who are not board members and the remainder are employees of
the Company who are not executive officers and consultants.

Proposed Amendments to the Plan

     The Board is proposing two  amendments to the Plan.  These  amendments  are
designed to provide greater  flexibility to  participants  in the Plan,  thereby
enhancing the Plan's incentive to participants.

     Under the Plan, as currently in force, options may not be transferred other
than  under  the  laws  of  decent  or   distribution.   This   restriction   on
transferability   of  options  was  required   based  on  previous   regulations
promulgated  under  Section  16(b) of the  Securities  Exchange Act of 1934,  as
amended.  Due to  changes  in  such  regulations,  however,  options  may now be
transferred by participants in stock option plans. The first proposed  amendment
would align the Plan with current regulations and provide greater flexibility to
participants  by removing  the current  restriction  on the  transferability  of
options  granted  under the Plan,  to permit the  exercise  of  options,  at the
discretion of the Compensation  Committee,  by transferees or beneficiaries  who
are family  members  or  spouses of an  optionee.  If  approved,  this  proposed
amendment  would  permit  an  optionee  to,  in  a  manner  established  by  the
Compensation Committee,  transfer options or designate a family member or spouse
as beneficiary or  beneficiaries  to exercise the rights of the Plan participant
and receive any property  distributable with respect to any option granted under
the Plan.  Notwithstanding  this proposed  amendment,  no option may be pledged,
alienated,   attached  or  otherwise  encumbered,   and  any  purported  pledge,
alienation,  attachment of encumbrance  thereof shall be void and  unenforceable
against the Company.

     In  addition,  under the current  Plan,  participants  who  exercise  stock
options must pay the Company such exercise  price in cash on the delivery of the
underlying  shares  of Common  Stock  then  owned by the  optionee.  The  second
amendment would permit,  at the discretion of the  Compensation  Committee,  the
"cashless  exercise"  of  options  under the Plan by  permitting  optionees  who
exercise an option to  surrender  that  number of shares of Common  Stock of the
Company subject to such option with an aggregate fair market value equivalent to
the aggregate  exercise price of the exercised option in lieu of cash payment of
the exercise price.

     For information concerning options granted under the Plan to directors, the
Chief  Executive  Officer  and the  Named  Executive  Officers  see  "Directors'
Compensation  - Directors'  Stock  Options,"  "Summary  Compensation  Table" and
"Option Grants In Last Fiscal Year."

     The Board of  Directors  recommends  a vote FOR  approval  of the  proposed
amendments to the  Non-Qualified  Stock Option Plan (Proposal No. 2 on the Proxy
Card).

                    PROPOSAL NO. 3 - RATIFICATION OF AUDITORS

     On  October  20,  1998,  the Audit  Committee  of the  Board of  Directors,
pursuant to authority granted by the Board of Directors,  approved the retention
of KPMG Peat Marwick LLP ("KPMG"),  independent certified public accountants, to
audit the consolidated  financial  statements of the Company for the fiscal year
ending  June 30,  1999.  KPMG  served as auditor of the  consolidated  financial
statements  of the Company for the fiscal  years ended June 30,  1998,  June 30,
1997, and June 30, 1996.  Representatives  of KPMG are expected to be present at
the Annual Meeting and will have the opportunity to make a statement should they
desire to do so.  Such  representatives  are also  expected to be  available  to
respond to questions.

     The Board of Directors  recommends a vote FOR ratification of the selection
of KPMG Peat Marwick LLP, independent certified public accountants, to audit the
consolidated financial statements of the Company for the fiscal year ending June
30, 1999 (Proposal No. 3 on the Proxy Card). 


                                       16
<PAGE>


                         ANNUAL REPORT TO STOCKHOLDERS

     The Company's  Annual Report to Stockholders for the fiscal year ended June
30, 1998 accompanies this Proxy Statement.

                             STOCKHOLDERS' PROPOSALS

     It is  anticipated  that  the  Company's  fiscal  1999  Annual  Meeting  of
Stockholders will be held on or about December 7, 1999.  Stockholders who intend
to present  proposals at such Annual Meeting of  Stockholders  must submit their
proposals to the Secretary of the Company on or before July 3, 1999.

                                     GENERAL

     The cost of soliciting proxies will be borne by the Company. In addition to
mailing,  proxies  may  be  solicited  by  personal  interview,   telephone  and
telegraph,  and by  directors,  officers  and regular  employees of the Company,
without special compensation  therefor.  The Company expects to reimburse banks,
brokers  and  other  persons  for their  reasonable  out-of-pocket  expenses  in
handling proxy materials for beneficial owners of the Company's Common Stock.

     Unless  contrary  instructions  are indicated on the proxy card, all Common
Shares  or Series A  Preferred  Shares  represented  by valid  proxies  received
pursuant to this  solicitation  (and not revoked  before they are voted) will be
voted FOR the  election  of the  nominees  for  directors  named  herein and FOR
Proposal No. 2 and Proposal No. 3.

     Any proxy given pursuant to this  solicitation may be revoked by the person
giving it at any time before it is voted.  Proxies may be revoked by filing with
the Secretary of the Company  written notice of revocation  bearing a later date
than the proxy, by duly executing a subsequent proxy relating to the same Common
Shares or Series A  Preferred  Shares or by  attending  the Annual  Meeting  and
voting in person.  Attendance  at the Annual  Meeting  will not in and of itself
constitute  revocation of a proxy unless the stockholder votes his or her Common
Shares or Series A Preferred Shares in person at the Annual Meeting.  Any notice
revoking a proxy should be sent to the Secretary of the Company, John A. Caruso,
at Enzon, Inc., 20 Kingsbridge Road, Piscataway, New Jersey 08854.

     The Board of Directors knows of no business other than that set forth above
to be  transacted at the meeting,  but if other matters  requiring a vote of the
stockholders  arise,  the  persons  designated  as proxies  will vote the Common
Shares or Series A Preferred  Shares  represented  by the proxies in  accordance
with their  judgment on such  matters.  If a  stockholder  specifies a different
choice on the proxy,  his or her Common Shares or Series A Preferred Shares will
be voted in accordance with the specification so made.

     Please complete,  sign and date the enclosed proxy card, which is revocable
as described herein, and mail it promptly in the enclosed postage-paid envelope.

     IT IS IMPORTANT THAT PROXIES BE RETURNED PROMPTLY.  WE URGE YOU TO FILL IN,
SIGN AND RETURN THE  ACCOMPANYING  PROXY CARD, NO MATTER HOW LARGE OR SMALL YOUR
HOLDINGS MAY BE.

                                  By order of the Board of Directors,


                                  John A. Caruso, Secretary

Piscataway, New Jersey
October 28, 1998



                                       17
<PAGE>


Proxy Card


                                   ENZON, INC.

                 Annual Meeting of Stockholders December 1, 1998
           This Proxy Is Solicited on Behalf of the Board of Directors

     Peter G. Tombros and John A. Caruso and each of them, as
proxies,  with full power of substitution in each of them, are hereby authorized
to represent and to vote,  as  designated  below and on the reverse side, on all
proposals  and in the  discretion  of the  proxies on such other  matters as may
properly  come before the annual  meeting of  stockholders  of Enzon,  Inc. (the
"Company")   to  be   held  on   December   1,   1998  or  any   adjournment(s),
postponement(s), or other delay(s) thereof (the "Annual Meeting"), all shares of
stock of the Company to which the  undersigned is entitled to vote at the Annual
Meeting.

     UNLESS  OTHERWISE  DIRECTED,  THIS PROXY WILL BE VOTED "FOR" PROPOSALS 1, 2
and 3 AND WILL BE VOTED IN THE  DISCRETION  OF THE PROXIES ON SUCH OTHER MATTERS
AS MAY  PROPERLY  COME  BEFORE  THE  ANNUAL  MEETING.  THE  BOARD  OF  DIRECTORS
RECOMMENDS THAT STOCKHOLDERS VOTE "FOR" PROPOSALS 1, 2 and 3.

(1)  Election of the following  nominees as Class III Directors to serve in such
     capacities until their successors are duly elected and qualified:


              ROLF A. CLASSON                    ROBERT LEBUHN


(Authority  to vote for any  nominee(s)  may be withheld  by lining  through the
name(s) of any such nominee(s).)

              /  / FOR all nominees     /  / WITHHOLD authority for all

(2)  Proposal to approve amendments to the Company's  Non-Qualified Stock Option
     Plan, as set forth in the Company's Proxy Statement dated October 28, 1998.

             /  / FOR                  /  / AGAINST            /  / ABSTAIN


                                     
<PAGE>


(3)  Ratification  of the  selection  of KPMG  Peat  Marwick  LLP to  audit  the
     consolidated financial statements of the Company for the fiscal year ending
     June 30, 1999.

             /  / FOR                /  / AGAINST             /  / ABSTAIN

/ /  Please  check  this box if you  expect to attend  the  Annual  Meeting in
     person.

                    (Please sign  exactly as name appears to the left,  date and
                    return.  If shares are held by joint  tenants,  both  should
                    sign.  When  signing as attorney,  executor,  administrator,
                    trustees or guardian,  please give full title as such.  If a
                    corporation, please sign in full corporate name by president
                    or other authorized officer.  If a partnership,  please sign
                    in partnership name by authorized person.)

                    Date:
                         -------------------------------------------------------

                         -------------------------------------------------------
                                              Sign Here 

                         -------------------------------------------------------
                                       Signature (if held jointly)
 
                         -------------------------------------------------------
                           Capacity (Title or Authority, i.e. Executor, Trustee)

                    PLEASE SIGN, DATE AND MAIL YOUR PROXY TODAY.



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