ENZON INC
8-K, 2000-02-23
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT

     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

       Date of Report (Date of earliest event reported) February 23, 2000

                                  ENZON, INC.
             (Exact name of registrant as specified in its charter)



          Delaware                      0-12957                  22-237286
(State or other jurisdiction          (Commission              (IRS Employer
      of incorporation)               File Number)            Identification)



                20 Kingsbridge Road, Piscataway, New Jersey 08854
               (Address of principal executive offices) (Zip Code)



        Registrant's telephone number, including area code (732) 980-4500




- --------------------------------------------------------------------------------
          (Former name or former address, if changed since last report)






<PAGE>



Item 5.  Other Events

     On February 23, 2000, Enzon,  Inc. issued a press release,  a copy of which
is attached as Exhibit 99.1 and incorporated by reference herein.

Item 7. Financial Statements, Pro Forma Financial Information and Exhibits.

     (c) Exhibit 99.1 - Press Release dated February 23, 2000.






<PAGE>



                                   SIGNATURES

     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
Registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.


Dated: February 23, 2000


                                                            ENZON, INC.
                                                     ----------------------
                                                           (Registrant)

                                                By:  /S/KENNETH J. ZUERBLIS
                                                     ----------------------
                                                     Kenneth J. Zuerblis
                                                     Vice President, Finance
                                                     and Chief Financial
                                                     Officer



                                                                    Exhibit 99.1

                    ENZON ANNOUNCES AWARD IN ARBITRATION WITH
                          YOSHITOMI FOR RECOMBINANT HSA

     PISCATAWAY,  NJ - February 23, 2000 -- Enzon, Inc. (NASDAQ: ENZN) announced
today  that  arbitrators  have  ruled in a  royalty  dispute  between  Enzon and
Yoshitomi  Pharmaceutical  Industries,  Inc.  Enzon was  awarded  a  one-percent
royalty on Yoshitomi  sales of  recombinant  Human Serum Albumin (rHSA) in Asia,
North  America and South  America.  The product  does not include any of Enzon's
platform technologies. The dispute began in 1998 regarding the royalties payable
on sales occurring in all licensed  territories  during the 15-year period after
the  first  approval  in  any  country.  In  November  1997,  Green  Cross,  the
predecessor to Yoshitomi, filed for approval to sell rHSA in Japan.

     Enzon is a biopharmaceutical  company developing advanced  therapeutics for
life-threatening  diseases  through  the  application  of its  proprietary  drug
delivery  and  targeting  technologies,  PEG  Modification,  Pro  Drug/Transport
technology and Single-Chain  Antigen-Binding (SCA(R)) protein technology.  Enzon
has several  products in various  stages of clinical  development  by itself and
with partners, including PEG-Intron with Schering-Plough,  which is in Phase III
clinical  trials for malignant  melanoma,  chronic  myelogenous  leukemia and in
combination  treatment  with   Schering-Plough's   product  REBETOL(R)  for  the
treatment of hepatitis C.  Schering-Plough  has filed for marketing  approval in
the U.S. and Europe for  PEG-INTRON  for the  treatment of chronic  hepatitis C.
Enzon also has two  products  on the  market,  ONCASPAR,  which is used to treat
Acute Lymphoblastic  Leukemia (ALL), and ADAGEN a treatment for a form of Severe
Combined  Immunodeficiency  Disease  (SCID),  commonly  known as the "Bubble Boy
Disease".  Enzon develops and markets products on its own and through  strategic
alliances,  which in addition to  Schering-Plough  Corporation  include  Alexion
Pharmaceuticals,  Inc.,  Baxter  Healthcare  Corporation,  Bristol-Myers  Squibb
Company, Eli Lilly & Company, and Rhone-Poulenc Rorer Pharmaceuticals, Inc.

     Certain  statements  made  in  this  press  release  related  to  potential
government approvals, market potential,  commercialization and sales revenues of
medical products and biologics,  as well as their  therapeutic  applications and
outcomes,  are  forward-looking  and  are  made  pursuant  to  the  safe  harbor
provisions of the Securities Litigation Reform Act of 1995. Such


<PAGE>


statements  involve risks and  uncertainties,  which may differ  materially from
those set forth in these  statements.  In addition,  the economic,  competitive,
governmental,  technological  and  other  factors  identified  in the  Company's
filings with the Securities and Exchange Commission could affect such results.

             This release is also available at http://www.enzon.com


                                       ###





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