CORTECH INC
PRER14A, 1998-08-07
PHARMACEUTICAL PREPARATIONS
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                            SCHEDULE 14A INFORMATION
Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

Filed by the Registrant [x]
Filed by a party other than the Registrant [ ]

Check the appropriate box:

[x]      Preliminary Proxy Statement
[ ]      Confidential,  for  Use  of the  Commission  Only  (as  permitted 
         by  Rule 14a-6(e)(2))
[ ]      Definitive Proxy Statement [ ] Definitive  Additional Materials
[ ]      Soliciting Material Pursuant to Rule 14a-11(c) or Rule 14a-12

                                  Cortech, Inc.
                (Name of Registrant as Specified In Its Charter)

                                       N/A
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):

[x]     No fee required

[ ]     Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.

        1)       Title of each class of securities to which transaction applies:


        2)       Aggregate number of securities to which transaction applies:



        3)       Per  unit  price  or other  underlying  value  of  transaction
                 computed  pursuant  to  Exchange  Act Rule 0-11 (set forth the
                 amount on which the filing fee is calculated  and state how it
                 was determined):



        4)       Proposed maximum aggregate value of transaction:



        5)       Total fee paid:


                 [ ] Fee paid previously with preliminary materials.

                 [ ] Check box if any part of the fee is offset as  provided
                 by  Exchange Act Rule  0-11(a)(2)  and identify the filing for
                 which the  offsetting fee was paid  previously.  Identify the
                 previous filing by registration statement number, or the Form
                 or Schedule and the date of its filing.

                 1)       Amount Previously Paid:

                 2)       Form, Schedule or Registration Statement No.:

                 3)       Filing Party:

                 4)       Date Filed:

<PAGE>









                                  Cortech, Inc.
                            6850 N. Broadway, Suite G
                             Denver, Colorado 80221
                                 (303) 650-1200

                                                                August __, 1998






Dear Stockholder:

         You are cordially  invited to attend Cortech,  Inc.'s Annual Meeting of
Stockholders,  which will begin at 9:00 a.m.  local time,  Friday,  September 4,
1998 at The Renaissance Hotel, 3801 Quebec Street, Denver, Colorado.

         Stockholders will vote on the proposals  detailed in the attached proxy
statement,  and  we  will  present  a  brief  status  report  on  the  Company's
operations.

         Regardless of your plans to join us on September  4th, we hope you will
sign,  date and return  your WHITE proxy card in the  envelope  provided at your
earliest  convenience.  If you have any  questions or need  assistance in voting
your shares, please call D.F. King & Co., Inc., which is assisting us, toll-free
at 1-800-848-3051. We look forward to your reply.


                                                        Sincerely yours,



                                                        Bert Fingerhut
                                                        Chairman

<PAGE>


                                  CORTECH, INC.

                                  ------------

                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                          TO BE HELD SEPTEMBER 4, 1998
                                  ------------


        NOTICE IS HEREBY  GIVEN  that the  Annual  Meeting  of  Stockholders  of
Cortech, Inc., a Delaware corporation ("Cortech" or the "Company"), will be held
on Friday,  September 4, 1998 at 9:00 a.m. local time at The Renaissance  Hotel,
3801 Quebec Street, Denver, Colorado for the following purposes:

   
        1.      To elect two Class I  directors  to hold  office  until the 2001
                annual meeting of stockholders or until his successor is elected
                and has  qualified  and, if the  stockholder  proposal set forth
                under  proposal  5 below is  approved,  to elect one  additional
                Class I  director  and one Class  III  director  to hold  office
                until,  respectively,  the  2001  and 2000  annual  meetings  of
                stockholders  or until  their  successors  are  elected and have
                qualified.
    

       2.       To adopt and approve an amendment to the  Company's  Certificate
                of Incorporation  that provides for a one-for-ten  reverse stock
                split of outstanding Cortech common stock.

       3.       To adopt and approve an amendment to the  Company's  Certificate
                of Incorporation that provides that the Board of Directors shall
                fix the number of directors.

       4.       To ratify the  selection of Arthur  Andersen LLP as  independent
                auditors of the Company for the fiscal year ending  December 31,
                1998.

   
       5.       To consider and act upon, if properly  presented,  a stockholder
                proposal  concerning  an  amendment to the  Company's  Bylaws to
                increase the number of directors,  which  proposal is opposed by
                the Board of Directors.
    

       6.       To transact such other  business as may properly come before the
                meeting or any adjournment or postponement thereof.

        The  foregoing  items of business are more fully  described in the Proxy
Statement accompanying this Notice.

        The Board of Directors  has fixed the close of business on July 10, 1998
as the record date for the  determination of stockholders  entitled to notice of
and to  vote at this  Annual  Meeting  and at any  adjournment  or  postponement
thereof.

                                 By Order of the Board of Directors,



                                 Bert Fingerhut
                                 Chairman

Denver, Colorado
August __, 1998


<PAGE>






        ALL STOCKHOLDERS ARE CORDIALLY  INVITED TO ATTEND THE MEETING IN PERSON.
WHETHER OR NOT YOU EXPECT TO ATTEND THE MEETING, PLEASE COMPLETE, DATE, SIGN AND
RETURN THE ENCLOSED  WHITE PROXY CARD AS PROMPTLY AS POSSIBLE IN ORDER TO ENSURE
YOUR  REPRESENTATION AT THE MEETING. A RETURN ENVELOPE (WHICH IS POSTAGE PREPAID
IF MAILED IN THE UNITED  STATES) IS ENCLOSED FOR THAT PURPOSE.  EVEN IF YOU HAVE
GIVEN YOUR PROXY, YOU MAY STILL VOTE IN PERSON IF YOU ATTEND THE MEETING. PLEASE
NOTE, HOWEVER, THAT IF YOUR SHARES ARE HELD OF RECORD BY A BROKER, BANK OR OTHER
NOMINEE  AND YOU WISH TO VOTE AT THE  MEETING,  YOU MUST  OBTAIN FROM THE RECORD
HOLDER A PROXY ISSUED IN YOUR NAME.


<PAGE>



                                                      

PRELIMINARY COPY


                                  CORTECH, INC.
                                  ------------

                                 PROXY STATEMENT
                                  ------------

General

         The enclosed  proxy is solicited on behalf of the Board of Directors of
Cortech, Inc., a Delaware corporation  ("Cortech" or the "Company"),  for use at
the  Annual  Meeting  of  Stockholders  (the  "Annual  Meeting")  to be  held on
September 4, 1998 at 9:00 a.m. local time, or at any adjournment or postponement
thereof,  for the purposes set forth  herein and in the  accompanying  Notice of
Annual Meeting.  The Annual Meeting will be held at The Renaissance  Hotel, 3801
Quebec  Street,  Denver,  Colorado.  The  Company  intends  to mail  this  proxy
statement  and  accompanying  proxy  card on or about  August 10,  1998,  to all
stockholders entitled to vote at the Annual Meeting.

   
         You probably have already  received an opposition  proxy statement (the
"Opposition  Proxy")  from  Asset  Value Fund  Limited  Partnership  ("AVF"),  a
dissident  stockholder that is attempting a hostile takeover of the Company.  In
connection with its hostile  takeover  attempts,  AVF is soliciting  proxies to,
among other things, amend the Company's Bylaws to increase the size of the Board
to seven members and,  subject to the approval of such  amendment,  to elect its
four  nominees to the Board (to fill the two Class I seats up for  election  and
the  two  vacancies  created  by  AVF's  proposed  Bylaw  amendment).  If AVF is
successful  in passing its  proposed  Bylaw  amendment  and in electing its four
nominees,  AVF  representatives  would  have  a  majority  of the  seats  on the
Company's Board of Directors and AVF would control Cortech.

         AVF is an  investment  vehicle  led by Paul  Koether,  who the  Company
believes is a notorious  greenmailer  with a  documented  history of  purchasing
short-term  positions in public  companies,  threatening  and waging  costly and
divisive  proxy  contests  with the  stated  purpose of  protecting  stockholder
interests,  and then selling out when offered an attractive  price. The Board of
Directors  urges  you not to  support  AVF's  hostile  attempt  to take over the
Company,  but to  carefully  review  the  information  contained  in this  proxy
statement and sign,  date and return the WHITE proxy card today in the enclosed,
postage pre-paid envelope.

         Ten years  ago,  Emerald  Partners,  a  partnership  formed by Paul and
Natalie  Koether,  sued to stop a merger  of May  Petroleum,  Inc.  and  several
companies  controlled  by Craig Hall,  the  defendant in the  lawsuit.  The Vice
Chancellor  of  the  Delaware  Chancery  Court,   Delaware's   corporate  court,
characterized both the Koethers'  partnership and the defendant as having little
concern for other stockholders:

         "As will be seen,  the  Court is placed in the  difficult  position  of
         having to choose between two  protagonists,  both of which seem to have
         little concern for the interests of the hapless minority stockholders."

         Looking  at  the  record  of  the  Koethers'  partnership,   the  court
commented:
    

         "Emerald obviously deals in many forms of shareholder blackmail,  i.e.,
         greenmail, in attempts to gain control of corporations or be bought out
         at substantial premiums."

   
         The Court eventually enjoined the merger, upholding Emerald's role as a
representative of the May stockholders, and commenting:

        "Emerald  has assumed the role here as being a fiduciary  for the
minority stockholders,  a role which is probably  entirely new to it. Having
assumed that role it will be  expected  to  fulfill  it in the  high  standards
required  by Delaware law. "

         The litigation, begun ten years ago, is still ongoing today.

         As recently as six months ago, AVF sold shares of FIND/SVP,  Inc.  back
to FIND/SVP at a substantial  premium over market value in  connection  with the
settlement of litigation  brought by the Koethers.  Unlike the Emerald  Partners
case, the FIND/SVP litigation did not involve derivative claims by AVF on behalf
of all FIND/SVP  stockholders;  instead AVF claimed it was deceived  into buying
additional  FIND/SVP  shares and canceling  plans to sell shares.  Twenty months
ago,  Pureworld  Inc.,  another  Koether-led  vehicle,  extracted  $825,000 from
American  Industrial  Properties REIT in a settlement as reimbursement for costs
and in consideration  for releases and standstill  agreement.  Like the FIND/SVP
litigation,  the claims in the American  Industrial  litigation  did not involve
derivative  claims  made by  Pureworld  on  behalf  of all  American  Industrial
stockholders;  instead  Pureworld was sued for violations of federal  securities
laws and Pureworld made  counterclaims  contesting the validity of provisions of
American  Industrial's  bylaws,  seeking to appoint an additional  trustee and a
receiver of American Industrial; and seeking to enjoin American Industrial until
appointment of an additional trustee.
    

         In its  campaign  materials,  AVF says it intends  to benefit  from its
Cortech  investment  only to the same extent  other  stockholders  benefit.  But
nothing  obligates  Koether  to live up to his  promise  if he takes  control of
Cortech.  We urge you to look into  Koether's  record before  casting a vote for
him!

         Your Board of Directors  remains  committed to the interests of Cortech
stockholders and maximizing the value of Cortech stock.  Cortech's Board members
include  scientists and businessmen  with years of experience in science and the
pharmaceutical  industry who believe that  Cortech's  technology  has value.  In
contrast,  Koether is proposing a slate which would be controlled by himself and
his  associates,  none of whom have  significant  scientific  or  pharmaceutical
industry experience.

Voting Rights and Outstanding Shares

        Only  holders of record of Common Stock at the close of business on July
10,  1998 (the  "Record  Date") will be entitled to notice of and to vote at the
Annual  Meeting.  At the close of  business  on the Record  Date the Company had
outstanding and entitled to vote 18,523,918  shares of Common Stock. Each holder
of record of Common  Stock on the Record  Date will be  entitled to one vote for
each share held on each matter to be voted upon at the Annual Meeting.

   
        Under  the  Bylaws  of the  Company,  a quorum  for the  transaction  of
business is constituted by the presence,  in person or by proxy,  of the holders
of a majority of the stock of the Company issued and outstanding and entitled to
vote at the meeting. A plurality of the votes of the shares present and entitled
to vote at the Annual  Meeting is required to approve the  election of directors
in Proposal 1. The  affirmative  vote of holders of a majority of the  Company's
issued and outstanding shares entitled to vote at the Annual Meeting is required
to approve  each of Proposals 2 and 3 and the  affirmative  vote of holders of a
majority of the shares present in person or by proxy and entitled to vote on the
matter at the Annual Meeting is required to approve each of Proposals 4 and 5.
    

        All votes will be tabulated by the  inspector of election  appointed for
the meeting,  who will  separately  tabulate  affirmative  and  negative  votes,
abstentions  and  broker  non-votes.  Abstentions  will be counted  towards  the
tabulation  of votes cast on proposals  presented to the  stockholders  and will
have the same effect as negative votes.  Broker  non-votes are counted towards a
quorum, but are not counted for any purpose in determining  whether a matter has
been approved.

Revocability of Proxies

        Any person giving a proxy in connection  with the Annual Meeting has the
power to revoke such proxy at any time before it is voted at the Annual  Meeting
(i) by delivering a written  notice of revocation of such proxy to the Secretary
of the Company at the Company's  principal  executive office,  6850 N. Broadway,
Suite G, Denver,  Colorado 80221, (ii) by executing and delivering a later dated
proxy to the  Company or its  solicitation  agents,  or (iii) by  attending  the
Annual  Meeting and voting in person at the Annual  Meeting.  Attendance  at the
Annual Meeting will not, by itself, revoke a proxy.

        There is no limit on the number of times that a  stockholder  may revoke
his or her proxy prior to the Annual  Meeting.  Only the latest dated,  properly
signed proxy card will be counted.

        IF YOU ALREADY SENT A PROXY CARD TO AVF, A DISSIDENT STOCKHOLDER THAT IS
ATTEMPTING A HOSTILE TAKEOVER OF THE COMPANY, YOU MAY REVOKE THAT PROXY AND VOTE
IN  ACCORDANCE  WITH THE  RECOMMENDATIONS  OF THE BOARD OF DIRECTORS BY SIGNING,
DATING AND MAILING THE ENCLOSED WHITE PROXY CARD IN THE ENVELOPE PROVIDED.


                                   Proposal 1
                              Election of Directors
            THE BOARD RECOMMENDS A VOTE FOR THE NOMINEES OF THE BOARD

        The Company's Certificate and Bylaws, each as amended, currently provide
that the Board of  Directors  shall be divided  into three  classes,  each class
consisting,  as  nearly  as  possible,  of  one-third  of the  total  number  of
directors, with each class having a three-year term.

   
        The Company  currently has a total of five directors,  consisting of two
Class I directors,  whose terms expire in 1998,  two Class II  directors,  whose
terms  expire in 1999 and one Class III  director,  whose term  expires in 2000.
Each of the  current  directors,  with  the  exception  of Bert  Fingerhut,  was
appointed to fill a vacancy on the Board created by the  resignations of Charles
Cohen, Ph.D., Donald Kennedy,  Ph.D. and Allen Misher,  Ph.D. effective July 21,
1998 and Kenneth R. Lynn, effective May 18, 1998. Such resignations were not the
result of any  disagreement  with the Company  and , in the case of Drs.  Cohen,
Kennedy and Misher,  had been contemplated  earlier this year in connection with
the Company's proposed merger with Biostar, Inc.  ("Biostar"),  which merger was
subsequently abandoned.

        Two Class I directors  will be elected at the Annual Meeting . The Board
of Directors has  nominated Dr.  Lawrence M. Gold and Joachim von Roy as Class I
directors  (term  expiring 2001) to be elected at the Annual  Meeting.  However,
AVF, a dissident stockholder, is attempting a hostile takeover of the Company by
proposing  Proposal 5 (the "AVF Proposal")  which would add two new directors to
the Board (one Class I director, with a term expiring in 2001, and one Class III
director,  with a term expiring  2000) and permit AVF to elect a majority of the
members  of the Board of  Directors.  The  Board of  Directors  opposes  the AVF
Proposal and recommends Proposal 3, which would protect the Company's classified
Board  structure  by  eliminating  the  possibility  of AVF or future  dissident
stockholders  from taking  control of the Company by  proposals  such as the AVF
Proposal.  However,  if Proposal 3 is defeated  and the AVF Proposal is properly
presented  and  approved,  then four  directors  will be  elected  at the Annual
Meeting.  The Board of Directors has  conditionally  nominated Drs. John P. Papp
and John C. Cheronis  (collectively,  the "Additional Nominees") to fill the two
vacancies (for Class I director and Class III director, respectively) created in
the event the AVF  Proposal  is  adopted  and the  Board is  increased  to seven
members.

        Directors  are elected by a plurality of the votes  present in person or
represented by proxy and entitled to vote at the meeting.  Shares represented by
executed WHITE proxy card will be voted,  if authority to do so is not withheld,
for the  election  of Dr.  Gold and Mr. von Roy as Class I director  and, in the
event the AVF  Proposal is  approved,  also for the  election  of Drs.  Papp and
Cheronis as Class I and Class III directors, respectively.
    

        The persons nominated for election have agreed to serve if elected,  and
management  has no reason to believe that such nominees will be unable to serve.
However,  in the event that any of such nominees  becomes unable or unwilling to
accept  nomination  or election  as a result of an  unexpected  occurrence,  the
shares  represented by the enclosed proxy will be voted for the election of such
substitute nominee as management may propose.

        Set forth below is biographical  information for the persons  (including
the  Additional  Nominees)  nominated for election to the Board of Directors and
each other person  whose term of office as a director  will  continue  after the
Annual Meeting,  including  information  furnished by them as to their principle
occupations at present and for the past five years,  certain  directorships held
by each,  their ages as of July 15,  1998 and the year in which each  continuing
director became a director of the Company.

       The Board of Directors  recommends a vote FOR each of the nominees listed
below.

Nominee for Election as Class I Director

   
         Lawrence M. Gold,  PhD. Dr. Gold, 56, has been Chairman of the Board of
NeXstar Pharmaceuticals,  Inc., an integrated  biopharmaceutical  company, since
1993 and Chief  Scientific  Officer of NeXstar  since 1995.  He was a founder of
NeXstar,  has served as a director of NeXstar  since its  inception  in 1991 and
served as Executive Vice  President of Research and  Development at Nexstar from
1991 to 1995.  From 1988 to 1992 Dr.  Gold was  Chairman  of the  Department  of
Molecular,  Cellular and Developmental  Biology at the University of Colorado at
Boulder.  He has been a professor at the University  since 1970 and has received
the  University's  Distiquished  Lectureship  Award.  Dr.  Gold was a founder of
Synergen,  Inc..,  a  biopharmaceutical  company,  and,  from 1981 to 1988,  was
Synergen's Co-Director of Research. He is a recipient of the National Institutes
of  Health  Merit  Award  and  Career  Development  Award and is a member of the
National Academy of Sciences.
    

     Joachim von Roy Mr. von Roy,  52, has been a director of the Company  since
July 1998. Mr. von Roy is a Principal of RvR Associates,  an independent  health
care consulting firm. From 1993 to 1997, he served as President of Bristol-Myers
Squibb  Pharmaceuticals,  Europe and,  from 1990 to 1993,  he was  President  of
Bristol-Myers Squibb Pharmaceuticals, Central Europe. Mr. von Roy is Chairman of
Health Initiative Europe Institute for Bagonalistics and a member of Kuratorium,
the German Lipid League.

Additional Nominees for Election as Class I and Class III Directors

         Class I Director:

   
         John P. Papp,  M.D. Dr. Papp,  59, is a  gastroenterologist  in private
practice who also holds a teaching  appointment  as a Clinical  Professor in the
Department of Medicine, College of Human Medicine, at Michigan State University,
an  appointment  he has held  since  May  1987.  He is a past  president  of the
American College of  Gastroenterology  and has served on and chaired a number of
medical committees.

         Class III Director:
    

     John C. Cheronis, M.D., Ph.D. Dr. Cheronis, 47, has been Founding Scientist
of the Company since 1996 and served as Vice President,  Research of the Company
from the Company's inception in 1982 to 1995. Dr. Cheronis was a director of the
Company from 1982 to 1995.  He is a diplomat of the  American  Board of Internal
Medicine.  Dr.  Cheronis  received his Ph.D.  and M.D.  from the  Department  of
Pharmacology and Physiology at the Pritzker School of Medicine of the University
of Chicago in 1978 and 1980, respectively.

   
    


Continuing Class II Directors

         Bert Fingerhut.  Mr. Fingerhut,  54, has been a director of the Company
since 1988 and Chairman of the Board and Acting Chief  Executive  Officer  since
May 1998.  Mr.  Fingerhut also served as Chairman of the Board from June 1991 to
April 1997. In addition to his service with the Company, Mr. Fingerhut presently
pursues private business and conservation  interests.  From 1984 to 1985, he was
Special Limited Partner and Senior Vice President of Odyssey Partners, a private
investment  partnership.  From 1965 to 1983,  he was General  Partner,  Managing
Director,  Executive  Vice  President and Director of Research of  Oppenheimer &
Company,  Inc.,  an  investment  banking and brokerage  firm.  Mr.  Fingerhut is
Chairman of the Board of Directors of Toxics Targeting,  a private company based
in Ithaca, N.Y. that tracks and provides information on toxic waste sites. He is
currently Chairman of the Governing Council of The Wilderness  Society, a member
of the Board of Directors of the Southern Utah Wilderness  Alliance,  a director
of the Grand Canyon Trust and Trustee of the Alaska Conservation Foundation. Mr.
Fingerhut also serves as a director of the Wyss Foundation.

     John E.  Repine,  M.D. Dr.  Repine,  53, has been a director of the Company
since July 1998.  Dr. Repine has been the President  (since 1993) and a Director
(since 1989) of the Webb-Waring  Institute for Biomedical Research.  He has also
been the James J. Waring  Professor in the Department of Medicine and Pediatrics
at the University of Colorado  Health Sciences Center since 1996. Dr. Repine was
elected to the American Society of Clinical Investigation and the Association of
American  Physicians.  He is also the recipient of an  Established  Investigator
Award from the American Heart  Association,  Basil O'Connor  Research Award from
the  March  of  Dimes  and  the   Bonfils-Stanton   Award  for  his  outstanding
contribution  to medicine  and  science.  Dr.  Repine  serves on the  scientific
advisory  boards of a number of  biotechnology  companies.  He currently holds 6
patents.

Continuing Class III Director

        Edward  Finkelstein.  Mr.  Finkelstein,  62, has been a director  of the
Company since July 1998. Mr.  Finkelstein has been a managing  partner of REM, a
real estate holding  company,  since 1986, and the President and Chief Executive
Officer of Edmark  Development  LLC, a commercial  real estate  development  and
management  company,  since 1990.  He has also served as the President and Chief
Executive  Officer of  Central  Motors,  a holding  company  of  Midwestern  car
dealerships,  since  1992,  and the  Chairman  and Chief  Executive  Officer  of
Rollabind,  Inc.,  the largest  manufacturer  of patented  disc binding  systems
worldwide,  since 1996. Between 1972 and 1991, Mr. Finkelstein was President and
Chief  Executive  Officer of Michigan  Sporting  Goods  Distributors,  Inc., the
parent company of MC Sports,  one of the largest retail  sporting good chains in
the world.

         The Board of Directors recommends a vote FOR the Board's nominees.

                                   Proposal 2
                          Approval of the Reverse Split
                   THE BOARD RECOMMENDS A VOTE FOR PROPOSAL 2

         The Board of Directors  of the Company has  unanimously  approved,  and
recommends that stockholders  approve, an amendment to the Company's Certificate
of  Incorporation  to effect a reverse split of the  Company's  Common Stock and
make a  corresponding  reduction  in the  authorized  number of shares of Common
Stock which the Company may issue (such actions  collectively  being referred to
as the "Reverse Split").  The Reverse Split, if approved by stockholders,  would
cause all issued and  outstanding  shares of the  Company's  Common  Stock to be
split, on a reverse basis, one-for-ten  (stockholders would receive one share of
Common  Stock for every ten shares  held  prior to the  Reverse  Split).  If the
Reverse  Split is approved at the Annual  Meeting,  the Company  intends to file
documents to effect the Reverse Split with the Secretary of State of Delaware as
soon as  practicable,  and the Reverse  Split will be effective on the date such
documents  are filed  (the  "Effective  Date").  As part of the  Reverse  Split,
Article V, Section 1 of the  Certificate  of  Incorporation  would be amended to
decrease the authorized  number of shares of capital stock which the Company may
issue from 52,000,000  shares to 7,000,000  shares,  5,000,000 of which shall be
Common Stock, and 2,000,000 of which shall be Preferred Stock.

   
         As described  below,  the primary  objective of the Reverse Split is to
increase the per share market price of the Common Stock.  On July 13, 1998,  the
Nasdaq Stock Market, Inc. ("Nasdaq") Listing  Qualifications Panel decided that,
as of the close of business on such date,  the  Company's  Common Stock would be
delisted from the Nasdaq National Market.  Nasdaq requires that the common stock
of companies  listed on the Nasdaq  National  Market must have a bid price of at
least $1.00 per share,  and the basis for the Panel's  decision was that the bid
price of the  Common  Stock was less than  $1.00 per  share.  As a result of the
delisting, the Common Stock currently trades on Nasdaq's OTC Bulletin Board.

         Nasdaq's  delisting  of the Common  Stock will have a number of adverse
effects on the  Company's  stockholders.  Availability  of current  market price
information  for the  Common  Stock and news  coverage  of the  Company  will be
limited. Delisting may have the effect of restricting investors' interest in the
Common Stock and may have a material  adverse  effect on the trading  market and
prices for the Common Stock as well as the Company's ability to issue additional
securities or to secure additional  financing.  Because of the adverse impact on
the  trading  market of the Common  Stock and the  potential  loss of  effective
trading markets, the volatility of the Common Stock may be increased.

         In addition, stocks with low per share prices are subject to additional
federal  and state  regulatory  requirements.  Because  the market  price of the
Common  Stock is less than $5 per  share,  the  Common  Stock  cannot be used as
collateral  for margin loans.  In addition,  if the Common Stock were priced and
less than $5 per share and deemed a "penny stock" under federal securities laws,
additional regulatory restrictions would apply. Although the price of the Common
Stock is less than $5 per share,  the Company  does not believe  that its Common
Stock is a penny stock under federal  securities laws, because the Company's net
tangible assets exceed the required threshold of $4 million.  However,  there is
no  assurance  that the Company will  continue to meet the net  tangible  assets
requirement  or other  exemptions  from the  definition  of a penny stock in the
future.

         On July 23, 1998, the Company appealed  Nasdaq's decision to delist the
Common  Stock to the Nasdaq  Listing and Hearing  Review  Council  (the  "Review
Council").  The basis for the Company's appeal is that the Company believes that
the failure of the Common Stock to comply with Nasdaq's  minimum $1.00 per share
bid price requirement will be cured by stockholder approval of the Reverse Split
at the Annual Meeting. However, even if the Reverse Split is approved, there can
be no  assurance  that  the  Company's  appeal  to the  Review  Council  will be
successful.  In  addition,  while the Company  believes it  currently  meets the
continued  listing  criteria  for the Nasdaq  National  Market  (other than with
respect to the minimum bid price), even if the decision of the Review Council is
favorable,  there  can be no  assurance  that the  Company  will  meet  Nasdaq's
continued listing criteria in the future (whether as a result of failure to meet
the minimum bid price requirement or other requirements imposed by Nasdaq).
    

         If the  Reverse  Split is not  approved  by  stockholders,  the Company
believes  that the Common  Stock will not be eligible to be traded on the Nasdaq
National  Market or the  Nasdaq  Small Cap  Market  because  the  Company is not
currently  able to meet certain of the Nasdaq's  initial  listing  requirements,
which are more stringent than the continued listing requirements. In particular,
the initial  listing  requirement of the Nasdaq National Market is a minimum bid
price of $5 per share,  and the initial listing  requirement of the Nasdaq Small
Cap Market is a minimum bid price of $4 per share.

         If the  Reverse  Split is approved by  stockholders  but the  Company's
appeal to the Review Counsel is  unsuccessful,  the Company may seek to have the
Common  Stock  listed on the  Nasdaq  Small  Cap  Market.  However,  there is no
assurance  that Nasdaq  would act  favorably on any request by the Company to be
listed on the Nasdaq Small Cap Market.

         On July 29, 1998, Nasdaq informed the Company that the Company would be
permitted to submit  information  to the Review  Council in connection  with the
Company's  appeal  until the close of business on  September  23,  1998.  Nasdaq
further  indicated  in its July 29, 1998 letter  that the Review  Council  would
issue a  decision  after  the NASD  Board of  Governors  had an  opportunity  to
consider the delisting  decision pursuant to NASD Rule 4880, an opportunity that
Nasdaq  indicated  would likely  occur at the  December  NASD Board of Governors
meeting.

         The Board of Directors believes that the Reverse Split is beneficial to
the Company's  stockholders as the Company will not have reasonable  grounds for
appealing the delisting of its Common Stock from the Nasdaq  National  Market if
the Reverse  Split is not  effected and if the market price for the Common Stock
does not otherwise meet Nasdaq's $1.00 minimum bid price  maintenance  standard.
In addition,  the Board of Directors  believes that the Reverse Split may permit
the  Company to have the Common  Stock  listed on the Nasdaq  Small Cap  Market,
which the Board of Directors  believes would offer advantages to stockholders as
compared with trading on Nasdaq's OTC Bulletin Board.

         For the foregoing reasons, the Board of Directors has determined that a
recapitalization through the Reverse Split would be in the best interests of the
Company and its stockholders,  and recommends  stockholders  approve the Reverse
Split.

Effects of the Reverse Split

         General Effects.  The principal effect of the Reverse Split would be to
decrease  the  number of  outstanding  shares  of the  Company's  Common  Stock.
Specifically,  the 18,523,918  shares of Common Stock issued and  outstanding on
the Record  Date would,  as a result of the Reverse  Split,  be  converted  into
approximately  1,852,392  shares  of  Common  Stock  (with  the  precise  number
depending upon the extent of fractional shares resulting from the Reverse Split,
which will be  converted  to cash  based  upon the  market  price for a share of
Common Stock on the trading day prior to  implementation  of the Reverse Split).
The number of shares of Common Stock  authorized  for issuance by the  Company's
Certificate   of   Incorporation   following   the   Reverse   Split   would  be
proportionately   adjusted   from   50,000,000   shares  to  5,000,000   shares.
Accordingly,  after the Reverse Split,  there would be approximately 3.1 million
"new" (or  post-Reverse  Split) shares of Common Stock ("New Shares")  available
for issuance by the Company.

         Effect on Market for Common Stock. On August 4, 1998, the closing price
of the Company's  Common Stock as quoted on the OTC Bulletin Board was $0.52 per
share. By decreasing the number of shares of Common Stock otherwise  outstanding
without altering the aggregate  economic interest in the Company  represented by
such  shares,  the  Board  believes  that the per  share  market  price  for the
Company's  Common  Stock will be  increased  in excess of the minimum  $1.00 bid
price required for continued listing of shares on the Nasdaq National Market.

         Effect on Stock  Options and  Warrants.  The total  number of shares of
Common Stock  issuable upon the exercise of options and warrants to acquire such
shares,  and the exercise price  thereof,  shall be  proportionally  adjusted to
reflect the Reverse Split.

         Effect under the Company's Rights Plan. Following the implementation of
the  Reverse  Split,  each  share of  Common  Stock  will  continue  to have one
preferred  share purchase right (a "Right")  associated  with it;  however,  the
number of shares of  Preferred  Stock  issuable  upon the exercise of each Right
shall be proportionally  adjusted to reflect the Reverse Split (i.e.,  following
the effectiveness of the Reverse Split, each Right, under certain circumstances,
would be eligible to purchase up to one-tenth of a share of Preferred Stock).

         Changes in  Stockholders'  Equity.  The Reverse  Split would reduce the
Company's  stated  capital,  which consists of the par value per share of Common
Stock multiplied by the number of such shares outstanding, from the amount which
would otherwise  exist (assuming the share amounts set forth above,  the Reverse
Split would  reduce the  Company's  stated  capital by  approximately  $70,000).
Although  the par  value of  Common  Stock  would  remain  at  $0.002  per share
following  the Reverse  Split,  stated  capital  would be decreased  because the
number of shares  outstanding would be reduced.  Correspondingly,  the Company's
additional paid-in capital,  which consists of the difference between its stated
capital and the  aggregate  amount paid to the Company  upon its issuance of all
then outstanding shares of Common Stock, would be increased.

     Appraisal  Rights.  Pursuant to the  Delaware  General  Corporate  Law, the
Company's  stockholders are not entitled to appraisal rights with respect to the
Reverse Split.

         Disadvantages.  The Company  believes  that, as a result of the Reverse
Split,  certain  shareholders  may incur  increased  expenses in selling odd-lot
shares of the Company's Common Stock.

   
 No Fractional Shares; Procedures for Exchange of Certificates

         No fractional  shares of Common Stock will be issued as a result of the
Reverse Split, no  certificates  for any fractional  shares will be issued,  and
fractional  share  interests  will not entitle the holder therof to exercise any
right of a stockholder with respect thereto.  In lieu of such fractional shares,
any holder of Common Stock (after  aggregating  all fractional  shares of Common
Stock  issuable to such holder)  will,  upon  surrender of such  holder's  stock
certificate(s)  representing  Common  Stock to  American  Securities  Transfer &
Trust, Inc. (the "Exchange  Agent"),  be paid in cash the dollar amount (rounded
to the nearest whole cent),  without  interest,  determined by multiplying  such
fractional  shares by the average of the reported  closing prices for the shares
on the OTC Bulletin  Board for the ten trading days  immediately  preceding  the
Effective Date.

         As soon as  practicable  after the Effective  Date,  the Exchange Agent
will mail to the registered holders of Common Stock (i) a Letter of Transmittal,
and (ii)  instructions for the use of the Letter of Transmittal in effecting the
surrender of the Common Stock  certificates  for  certificates  representing New
Shares.  Upon surrender of a certificate to the Exchange Agent,  together with a
duly executed  Letter of Transmittal  and such other documents as may reasonably
be required by the  Exchange  Agent or Cortech,  the holder of such  certificate
shall be entitled to receive in exchange therefor a certificate representing the
whole number of New Shares that such holder has the right to receive.

If any stock certificate has been lost, stolen or destroyed, Cortech may require
the  owner  of  such  lost,  stolen  or  destroyed  certificate  to  provide  an
appropriate  affidavit and to deliver a bond as indemnity against any claim that
may be  made  against  the  Exchange  Agent  or  Cortech  with  respect  to such
certificate.

STOCKHOLDERS  SHOULD NOT SURRENDER THEIR STOCK  CERTIFICATES  FOR EXCHANGE UNTIL
THEY RECEIVE A LETTER OF TRANSMITTAL FROM THE EXCHANGE AGENT.
    

Federal Income Tax Consequences

         The following  summary of the federal  income tax  consequences  of the
Reverse Split is based on current law,  including  the Internal  Revenue Code of
1986, as amended, and is for general information only. The tax treatment for any
stockholder may vary depending upon the particular  facts and  circumstances  of
such  stockholder.   Certain   stockholders,   including  insurance   companies,
tax-exempt organizations, financial institutions,  broker-dealers,  non-resident
aliens,  foreign  corporations  and persons who do not hold Common  Stock of the
Company as a capital asset, may be subject to special rules not discussed below.
Accordingly, each stockholder should consult his or her tax advisor to determine
the particular tax  consequences  to him or her of the Reverse Split,  including
the application and effect of federal,  state, local or foreign income taxes and
other laws.

         The receipt of whole New Shares  (excluding  fractional  New Shares) in
the  Reverse  Split  should be  non-taxable  for  federal  income tax  purposes.
Consequently,  a stockholder receiving New Shares will not recognize either gain
or loss, or any other type of income,  with respect to whole New Shares received
as a  result  of  the  Reverse  Split.  In  addition,  the  tax  basis  of  such
stockholder's  shares of Common Stock prior to the Reverse Split will carry over
as the tax basis of the stockholder's New Shares.  The holding period of the New
Shares should also include the stockholder's  holding period of the Common Stock
prior to the Reverse  Split,  provided  that such  Common  Stock was held by the
stockholder as a capital asset on the Effective Date.

         Any  stockholder  who receives  cash in lieu of a fractional  New Share
pursuant  to the  Reverse  Split  will  recognize  gain  or  loss  equal  to the
difference  between the amount of cash received and the portion of the aggregate
tax basis in his or her shares of Common Stock  allocable to such fractional New
Share.  If the  shares of  Common  Stock  were  held as a  capital  asset on the
Effective  Date, then the  stockholder's  gain or loss will be a capital gain or
loss. Such capital gain or loss will be a long-term  capital gain or loss if the
stockholder's  holding  period  for the  shares of Common  Stock is longer  than
eighteen months, a short-term capital gain or loss if the stockholder's  holding
period is twelve months or less and mid-term  gain or loss if the  stockholder's
holding period is longer than twelve months and less than eighteen months.

         Based on certain  exceptions  contained  in  regulations  issued by the
Internal  Revenue  Service,  the  Company  does  not  believe  that  it  or  its
stockholders would be subject to backup  withholding or informational  reporting
with respect to cash distributed in lieu of fractional New Shares.

Exchange of Shares

         On or  after  the  Effective  Date,  the  Company  will  mail  to  each
stockholder  of record a letter  of  transmittal.  Stockholders  will be able to
receive a certificate  representing New Shares and, if applicable,  cash in lieu
of a  fractional  New Share  only by  transmitting  to the  Exchange  Agent such
stockholder's stock  certificate(s) for shares of Common Stock outstanding prior
to the Reverse Split,  together with the properly  executed and completed letter
of transmittal, and such evidence of ownership of such shares as the Company may
require.  Stockholders  will not receive  certificates for New Shares unless and
until the  certificates  representing  their shares of Common Stock  outstanding
prior to the  Reverse  Split are  surrendered.  Stockholders  should not forward
their  certificates  to the Exchange  Agent until the letter of  transmittal  is
received  and  should  surrender  their  certificates  only with such  letter of
transmittal.

         Payment  in  lieu  of a  fractional  New  Share  will  be  made  to any
stockholder  entitled  thereto  promptly  after  receipt  by the  Company or its
Exchange  Agent  of  a  properly  completed  letter  of  transmittal  and  stock
certificate(s) for all of his or her shares of Common Stock outstanding prior to
the Reverse Split.  There will be no service charge payable by  stockholders  in
connection  with the exchange of  certificates or in connection with the payment
of cash in lieu of the issuance of a fractional  New Share.  These costs will be
borne by the Company.

Required Vote

         The  affirmative  vote of the  holders of a majority  of the issued and
outstanding  shares entitled to vote on the matter at the Annual Meeting will be
required to approve the Reverse Split described in this Proposal 2.

         The Board of Directors recommends a vote FOR Proposal 2.

                                   Proposal 3
        Approval of Amendment to Certificate of Incorporation Confirming
              the Board's Authority to Fix the Number of Directors
                   THE BOARD RECOMMENDS A VOTE FOR PROPOSAL 3

         Article IX,  Section 1 of the Company's  Certificate  of  Incorporation
currently  provides  that the number of directors of the Company  shall be fixed
from time to time in the manner  provided in the Bylaws and may be  increased or
decreased  from time to time in the manner  provided in the  Bylaws.  Article 3,
Section 3.1 of the Company's Bylaws provides, in pertinent part, that the number
of directors  shall be one or more,  as fixed from time to time by resolution of
the Board of Directors.  The Board of Directors has  unanimously  approved,  and
recommends that stockholders  approve, an amendment to the Company's Certificate
of  Incorporation  to restate  Article IX, Section 1 in its entirety as follows:
"The exact number of directors of the Company shall be  determined  from time to
time by resolution of the Board of Directors."

   
         The  proposed  amendment is designed to resolve the question of whether
dissident  stockholders can amend the Bylaws to increase the number of directors
and  then  nominate  directors  to  fill  the  vacancies  created  by the  Bylaw
amendment.  This  approach  allows a dissident  to elect a majority of the board
members at a single  meeting.  This is the strategy  currently being followed by
AVF. The Board of  Directors  believes  that it is in the best  interests of the
Company and its  stockholders to defeat  efforts,  such as those currently being
employed by AVF through the AVF Proposal  (described  under Proposal 5), to take
control of the Board.
    

         The Company has had a classified  Board structure since 1992. The Board
of Directors  believes that a classified  Board  continues to serve the Company,
its  stockholders  and those with whom the  Company is seeking to do business by
permitting  all parties to rely on the  consistency  and continuity of corporate
policy. This is particularly important to a research-based  organization such as
the Company,  where product  development  often requires many years. At the same
time, annual elections in which approximately  one-third of the Board is elected
each year offer  stockholders a regular  opportunity  to renew and  reinvigorate
corporate  decision-making  while  maintaining  the basic integrity of corporate
policy from year-to-year.

         In addition,  in the event of any unfriendly or unsolicited proposal to
take over or  restructure  the  Company,  such as the hostile  takeover by proxy
contest  currently being undertaken by AVF, a classified board structure permits
the Company to negotiate with the sponsor, to consider alternative proposals and
to assure that stockholder value is maximized.

   
         The Board of Directors  believes that the approval of the amendment set
forth in Proposal 3 is important in order to eliminate the possibility of AVF or
future  dissident  stockholders  from mounting a hostile takeover of the Company
through  proposals,  such as the  AVF  Proposal,  to  elect  a  majority  of the
directors at a single meeting.
    

         The  affirmative  vote of the  holders of a majority  of the issued and
outstanding  shares entitled to vote on the matter at the Annual Meeting will be
required for the adoption of the amendment contained in Proposal 3.

         The Board of Directors recommends a vote FOR Proposal 3.


                                   Proposal 4
                Ratification of Selection of Independent Auditors
                   THE BOARD RECOMMENDS A VOTE FOR PROPOSAL 4

         The  Board  of  Directors  has  selected  Arthur  Andersen  LLP  as the
Company's  independent auditors for the fiscal year ending December 31, 1998 and
has  further  directed  that  management  submit the  selection  of  independent
auditors for  ratification by the  stockholders  at the Annual  Meeting.  Arthur
Andersen  LLP  has  audited  the  Company's  financial  statements  since  1989.
Representatives  of Arthur Andersen LLP are expected to be present at the Annual
Meeting, will have an opportunity to make a statement if they so desire and will
be available to respond to appropriate questions.

         Stockholder ratification of the selection of Arthur Andersen LLP as the
Company's  independent  auditors  is not  required  by the  Company's  Bylaws or
otherwise. However, the Board is submitting the selection of Arthur Andersen LLP
to the stockholders for ratification as a matter of good corporate practice.  If
the stockholders fail to ratify the selection, the Audit Committee and the Board
will  reconsider  whether or not to retain that firm.  Even if the  selection is
ratified,  the Board in its discretion  may direct the  appointment of different
independent  auditors at any time during the year if they  determine that such a
change would be in the best interests of the Company and its stockholders.

         The affirmative vote of the holders of a majority of the shares present
in person or  represented  by proxy and  entitled to vote at the Annual  Meeting
will be  required  to  approve  Proposal 4  ratifying  the  selection  of Arthur
Andersen LLP.

         The Board Of Directors recommends a vote FOR Proposal 4.


                                   Proposal 5
           Solicitation in Opposition to AVF Proposal to Increase the
                  Size of the Board THE BOARD RECOMMENDS A VOTE
                               AGAINST PROPOSAL 5

   
         Article 3, Section 3.1 of the Company's Bylaws  provides,  in pertinent
part,  that the number of directors  shall be one or more, as fixed from time to
time by resolution of the Board of Directors. According to the Opposition Proxy,
AVF proposes to amend  Article 3, Section 3.1 of the Bylaws to fix the number of
directors to serve on the Board of Directors at seven. As described earlier, the
Company has had a classified  Board of Directors  since 1992.  With a classified
Board of Directors,  only  one-third of the board members are elected in any one
year.  The  Company  believes  that the AVF  Proposal is  inconsistent  with the
Company's classified Board of Directors because it would allow a majority of the
directors to be elected at one  election.  As asserted by AVF in the  Opposition
Proxy,  the AVF  Proposal  is  designed to enable AVF to elect a majority of the
Board at this election, thereby permitting AVF's representatives to constitute a
majority of the Company's directors and AVF to control the Company.

         The Board of  Directors  believes  that the AVF  Proposal is not in the
best interests of the Company and its stockholders  and has unanimously  adopted
Proposal 3, which would amend the  Company's  Certificate  of  Incorporation  to
prevent AVF or other dissident  stockholders  from attempting to take control of
the Company by proposing such a Bylaw  amendment.  In addition to helping assure
continuity and stability of the Company's  corporate policies and strategies,  a
classified  board  structure  permits  the  Company,  in the  face of a  hostile
takeover attempt or unsolicited proposal, time to negotiate with the sponsor, to
consider  alternative   proposals  and  to  assure  that  stockholder  value  is
maximized--in  other  words,  the  classified  board is  designed to protect the
Company and stockholders  precisely  against  corporate raiders such as Koether.
Given  Koether's   documented  history  of  greenmail,   hostile  takeovers  and
contentious  litigation,  the Board of Directors urges you to carefully consider
the Board's reasons for opposing the AVF Proposal.

         AVF presently  owns  approximately  10.8% of the Company's  outstanding
Common Stock (approximately 15% when combined with the holdings of Mark and Fred
Jaindl who are  participating in the Opposition Proxy  solicitation),  acquiring
its  interest  in the  fall of 1997  with the  announced  intention  of  seeking
representation  on the Board  through a proxy  contest or  otherwise.  In recent
months  the  Board of  Directors  has  worked  hard to try to  negotiate  a fair
settlement with Koether, but he appears to want nothing less than control of the
Company for his (and the Jaindls') 15% interest.  The Board urges holders of the
remaining 85% of the Company's outstanding Common Stock to look at the Koethers'
twenty year history of  greenmail  transactions  before  turning over control of
Cortech to AVF.
    

         The  affirmative  vote of the  holders of a majority  of the issued and
outstanding  shares  present in person or  represented  by proxy and entitled to
vote at the Annual  Meeting  will be  required  to approve  the Bylaw  amendment
described in Proposal 5.

         In order to defeat the hostile  takeover  attempt by Koether and ensure
that the interests of all the Company's stockholders are taken into account, the
Board of Directors recommends a vote AGAINST Proposal 5.


                              SECURITY OWNERSHIP OF
                    CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

        The  following  table  sets  forth  certain  information  regarding  the
ownership  of the  Company's  Common  Stock  as of July 24,  1998  by:  (i) each
director and nominee for director;  (ii) each of the executive officers named in
the Summary  Compensation  Table under the caption  "Compensation  of  Executive
Officers" below;  (iii) all executive officers and directors of the Company as a
group;  and (iv) all those known by the Company to be beneficial  owners of more
than five percent of its Common Stock.



                                                 Beneficial Ownership (1)

Name of Beneficial Owner                 Number of Shares       Percent of Total

Asset Value Fund Limited Partnership(2)       2,000,000               10.80%
 P.O. Box 74
 Bedminister, NJ

BVF Partners, L.P.(3)                         1,180,752                6.37%
 333 West Wacker Drive, Suite 1600
 Chicago, IL

Bert Fingerhut(4)                               563,205                3.02%

   
Edward Finkelstein                              444,025                2.40%

Dr. Lawrence M. Gold                                 --                  --

Dr. John E. Repine (5)                            5,000                  --

    

Joachim von Roy                                      --                  --

   
  Dr. John P. Papp                               70,123                   *

Dr. John C. Cheronis(6)                         486,891                2.68%

Kenneth R. Lynn(7)                                3,433                   *

Joseph L. Turner(8)                             140,984                   *
    

All executive officers and directors as a
group (5 persons)(9)                          1,263,872               6.68%
- --------------------

* Less than one percent.

(1)    This table is based upon information  supplied by the Company's officers,
       directors and principal stockholders and Schedules 13D and 13G filed with
       the  Securities and Exchange  Commission  (the "SEC").  Unless  otherwise
       indicated  in the  footnotes  to this  table  and  subject  to  community
       property  laws where  applicable,  the Company  believes that each of the
       stockholders  named in this table has sole  voting and  investment  power
       with respect to the shares  indicated as beneficially  owned.  Applicable
       percentages are based on 18,523,918 shares  outstanding on July 24, 1998,
       adjusted as required by rules promulgated by the SEC.

(2)     According to Amendment  No. 12 to the Schedule 13D filed with the SEC on
        July 17, 1998 by Asset Value. The sole general partner of Asset Value is
        Asset Value  Management,  Inc., a Delaware  corporation and wholly owned
        subsidiary of Kent Financial Services, Inc., a Delaware corporation.  On
        February 10,  1998,  Mark W. Jaindl and  Frederick  J. Jaindl  acquired,
        respectively,  250,000 shares and 520,000 shares of Company Common Stock
        from Asset Value in a privately negotiated  transaction.  Mark Jaindl is
        the son of Fred Jaindl and a director of a company  that might be deemed
        to be under the common  control of Asset Value by virtue of common stock
        ownership.  Although  Asset Value and the Jaindls  file  jointly,  Asset
        Value  disclaims  membership  in a group with the Jaindls and  disclaims
        beneficial ownership of the shares owned by the Jaindls.

(3)     According  to  Schedule  13D  filed  with  the  SEC on May  16,  1997 by
        Biotechnology  Value Fund,  L.P.  ("BVF").  Includes  638,796 Shares BVF
        beneficially  owns and has shared  dispositive and voting power with BVF
        Partners,  L.P.  ("Partners").  Partners  and BVF Inc.  share voting and
        dispositive  power over the 1,180,752  shares they own with, in addition
        to BVF, the managed  accounts on whose behalf  Partners,  as  investment
        manager, purchased such shares.

(4)     Includes  options to  purchase  153,010  shares,  which are  exercisable
        within 60 days of the date of this table.  Also  includes  3,000  shares
        held by Mr.  Fingerhut's wife and 17,000 shares by Mr. Fingerhut's minor
        daughter.

(5)     Includes options to purchase 5,000 shares, which are exercisable within
        60 days of this table.

   
(6)     Includes  options to  purchase  107,000  shares,  which are  exercisable
        within 60 days of the date of this table.  Also  includes  73,666 shares
        held in trust for Mr. Cheronis' children.

(7)     Mr. Lynn resigned as an officer of the Company on May 18, 1998.

(8)    Mr.  Turner  resigned  as an officer of the  Company on December 1, 1997.
       Includes options to purchase 128,066 shares, which are exercisable within
       60 days of the date of this table.
    

(9)    Includes options to purchase a total of 391,792 shares, which are
       exercisable within 60 days of the date of this table by executive 
       officers and directors.

                          BOARD COMMITTEES AND MEETINGS

        During the year ended  December  31, 1997,  the Board of Directors  held
nine meetings.  Each incumbent  director then in office attended at least 75% of
the  aggregate  number of meetings of the Board and of the  Committees  on which
such  director  served.  The  Board  has  an  Audit  Committee,  a  Compensation
Committee, an Equity Committee and a Nominating Committee.

        The Audit  Committee  meets with the Company's  independent  auditors at
least  annually  to review  the  results  of the annual  audit and  discuss  the
financial  statements;  recommends to the Board the  independent  auditors to be
retained;  and receives and considers the accountants'  comments as to controls,
adequacy of staff and management  performance  and procedures in connection with
audit  and  financial  controls.  The Audit  Committee,  which  during  1997 was
composed of Mr. Fingerhut and Dr. Cohen, met once during 1997.

        The Compensation Committee makes recommendations concerning salaries and
incentive  compensation,   awards  stock  options  to  officers,  employees  and
consultants  under the  Company's  stock option plans and  otherwise  determines
compensation levels and performs such other functions regarding  compensation as
the Board may  delegate.  The  Compensation  Committee,  which  during  1997 was
composed of Mr. Fingerhut and Drs. Kennedy and Misher, met once during 1997.

        The Equity  Committee  administers  the Company's stock option plans for
non-officer  employees  only and makes stock option grants to such employees not
in excess of 20,000  shares.  All option  grants in excess of this limit and all
option grants to officers must be approved by the  Compensation  Committee.  The
Equity  Committee,  which during 1997 was composed of Mr. Lynn, did not take any
action during 1997.

        The Nominating Committee interviews, evaluates, nominates and recommends
individuals  for  membership  on the Board of Directors  and  committees  of the
Board, and for election as officers of the Company, and, in connection with such
duties,  monitors  and makes  recommendations  with respect to  compensation  of
directors.  No procedure has been established for the  consideration of nominees
recommended by the stockholders.  In addition,  the Nominating Committee reviews
certain matters of Board governance, including evaluation of committee structure
and function and Board performance.  The Nominating Committee, which during 1997
was composed of Drs.
Kennedy and Misher, did not meet during 1997.


                             EXECUTIVE COMPENSATION

Compensation of Directors

        Under the 1992 Amended and Restated Non-Employee Directors' Stock Option
Plan (the "1992  Directors'  Plan"),  which expired by its terms on December 31,
1997, each  non-employee  director  received options to purchase Common Stock of
the Company as  compensation  for his or her services as a director and received
additional  options  under such Plan for  service on certain  committees  of the
Board.  In addition,  options were, and continue to be, granted to  non-employee
directors  outside  of such  Plan.  To  date,  no plan  has  replaced  the  1992
Directors' Plan. Outside directors receive $1,000 per Board meeting attended and
$1,000 per committee  meeting  attended if held on a non-Board  meeting occasion
and an additional $6,000 annually.

        Option  grants  under  the  1992  Directors'  Plan  were  automatic  and
non-discretionary. Each person who was a non-employee director of the Company as
of the adoption date of the 1992 Directors'  Plan was granted options  generally
covering  25,000 shares,  with  adjustments  to equalize the directors'  overall
options in light of options  previously  granted to them. Such options generally
become  exercisable  ("vest") in year-end  installments  of 5,000  shares.  Each
member of the  Compensation  and Audit  Committees  received options covering an
additional  500 shares for each committee on which he served.  In addition,  (a)
each person subsequently  elected for the first time as a non-employee  director
is granted an option on the date of his or her initial election as a director to
purchase a pro rata portion of 25,000  shares,  depending upon when he or she is
elected,  which options generally vest in year-end installments of 5,000 shares;
(b)  each  person  subsequently  elected  for the  first  time to the  Audit  or
Compensation  Committee  is granted an option to purchase  500 shares if elected
before July 1, or a portion  thereof,  prorated on a quarterly basis, if elected
after such date, vesting in full on December 31; (c) each non-employee  director
receives an annual option to purchase an additional number of shares, determined
by  multiplying  5,000  by a  fraction,  the  numerator  of which is $20 and the
denominator  of which is the fair market  value per share of the Common Stock on
the grant date, subject to minimum and maximum limits of 2,500 and 5,000 shares,
respectively,  vesting  quarterly  over five  years;  and (d) each  non-employee
director  who is a  member  of the  Company's  Audit or  Compensation  Committee
receives an annual  option to purchase  500 shares,  vesting in full on December
31.  Vesting of all options is subject to  continued  service as a  non-employee
director or employee of the Company  during the vesting  period and, in the case
of options  granted  for service on a  committee,  to  continued  service on the
applicable  committee.  As of July 24, 1998,  1,650  options had been  exercised
under the 1992 Directors' Plan.

        All directors are reimbursed  for their  expenses  incurred in attending
Board of Directors  meetings.  Directors who are employees of the Company do not
receive separate compensation for their services as directors.

        During the fiscal year ended December 31, 1997,  Mr.  Fingerhut and Drs.
Cohen,  Misher and Kennedy received options pursuant to the 1992 Directors' Plan
covering   6,000  shares,   5,000   shares,   5,500  shares  and  5,500  shares,
respectively, each at an exercise price of $1.47 per share.



<PAGE>


Compensation of Executive Officers

        The following  table shows for the fiscal years ended December 31, 1997,
1996 and 1995,  compensation  awarded or paid to, or earned by,  each person who
served as (i) the Company's  Chief  Executive  Officer  during 1997 and (ii) the
Company's other most highly compensated  executive officers at December 31, 1997
(collectively the "Named Executive Officers"):

                           SUMMARY COMPENSATION TABLE

                                                  Long-Term
                       Annual Compensation       Compensation
                                                    Awards

Name and                                  Other Annual   Securities    All Other
Principal Position Year Salary($) Bonus($)Compensation($)Underlying Compensation
                                                           Options(#)     ($)(1)

Kenneth R. Lynn (2)1997 $265,513 $65,000       --              --         $1,141
  President, Chief 1996  265,006  65,000       --          75,000          1,174
  Executive Officer 1995 230,499  75,000       --         275,000          1,099
  and Chairman of the Board

Joseph L. Turner (3)1997 165,537      --       --              --          2,165
  Vice President,   1996 154,533  25,000       --          40,000          2,399
  Finance and       1995 155,349  30,000       --          64,000          2,009
  Administration, Chief Financial Officer
  and Secretary

Diarmuid Boran (4)  1997 140,364  30,000       --              --          1,708
  Vice President,   1996 140,046  25,000       --          40,000          1,707
  Corporate         1995 112,493  30,000       --          64,000          1,386
  Development and Planning

- -----------------

(1)      Includes  matching  payments by the  Company  under its 401(k) Plan and
         premiums paid by the Company for group term life  insurance.  For 1997,
         the amounts were $631 and $510, respectively,  for Mr. Lynn; $1,295 and
         $870, respectively,  for Mr. Turner; and $1,404 and $304, respectively,
         for Mr. Boran.

(2)      Mr. Lynn left all  positions  with the Company as of May 18,  1998.  In
         accordance  with the Board's  determination  that Mr. Lynn's  departure
         constituted a Termination  Event under the Executive  Compensation  and
         Benefits Agreement dated as of October 14, 1997 between the Company and
         Mr.  Lynn,  Mr.  Lynn was  entitled to receive  the  benefits  provided
         thereunder,  subject  to the  modifications  set  forth  in the  letter
         agreement  dated May 18, 1998  between Mr. Lynn and the Board:  (i) the
         lump salary  continuation  payment  was limited to 20 months  salary or
         $441,667,  (ii) no pro rata  bonus was paid and  (iii) all  outstanding
         options held by Mr. Lynn were terminated and extinguished.  Pursuant to
         the letter  agreement,  Mr. Lynn agreed to make himself  available as a
         consultant to the Company through June 30, 1998 at a rate equal to half
         of his former rate of  compensation;  consulting fees totaling  $17,100
         were paid to Mr. Lynn  during such  period.  In  addition,  the Company
         entered into an indemnity  agreement with Mr. Lynn whereby it agreed to
         indemnify  him  against  claims  arising  in  connection  with  acts or
         omissions  arising  out  of  his  service  as  a  director,  executive,
         employee, consultant and/or agent of the Company.

(3)      Mr.  Turner  resigned as an officer  and  employee of the Company as of
         December 1, 1997. At such time, Mr. Turner and the Company entered into
         an agreement  pursuant to which Mr. Turner  served as a consultant  and
         continued to receive his former  salary  through  June 30, 1998.  Stock
         options held by Mr. Turner at the time of his resignation  continued to
         vest until June 30, 1998.

(4)      Mr. Boran became an executive  officer in 1995. In May 1998,  Mr. Boran
         was  appointed  Chief  Operating  Officer  and Acting  Chief  Financial
         Officer of the Company.



<PAGE>

 
Stock Option Grants and Exercises

         The Company  grants  options to its executive  officers  under its 1993
Equity  Incentive  Plan.  No options  were  granted to the  Company's  executive
officers in 1997.  As of July 15,  1998,  options to purchase a total of 632,483
shares  were  outstanding  under the 1993 Equity  Incentive  Plan and options to
purchase 836,627 shares remained available for grant thereunder.

         Aggregated Option Exercises in Fiscal 1997 and Value of Options
                              At End of Fiscal 1997

                                    Number of Securities    Value of Unexercised
                                    Underlying Unexercised         In-the-Money
                                    Options at End of         Options at End of
              Shares Acquired Value   Fiscal 1997 (#)         Fiscal 1997($)(1)
Name          On Exercise (#) Realized($)Exer/Unexer  Exercisable/Unexercisable

Kenneth R. Lynn   --            --     275,009/174,991               $0/$0
Joseph L. Turner  --            --      101,305/62,695                 0/0
Diarmuid Boran    --            --       79,940/66,560                 0/0
- ----------------

(1)      Based on the closing price of the Company's Common Stock on December 
         31, 1997 ($0.594) minus the exercise price of the options.

Employment Contracts and Severance Plan

         The Company adopted the Executive Officers' Severance Benefit Plan (the
"Severance Plan") on September 18, 1995, which was amended on December 13, 1996,
to encourage senior employees to work in the Company's best interests  following
a change in control.  In the event of an  involuntary  termination of employment
within 60 days prior and 30 months following a change in control,  all employees
employed  at the  level of Vice  President  or above and such  other  management
employees  as may be  designated  by the Chief  Executive  Officer  will receive
compensation  during the Benefit Period (defined  below),  a proportional  bonus
payment if one was received the year preceding the year in which the termination
date occurs, and all outstanding unvested stock options will become fully vested
on the termination date. The "Benefit Period" for employees other than the Chief
Executive  Officer  is the period  commencing  on the  termination  date and (i)
continues  for 18 months  following  such date if the date occurs within 60 days
prior or 12 months after a change in control,  or (ii)  continues for the period
following  the date the  employee  becomes  eligible  determined  by reducing 30
months by the number of months the eligible employee was employed by the Company
following a change in control.  With respect to the Chief Executive Officer, the
"Benefit  Period"  is the Chief  Executive  Officer's  termination  date and (i)
continues  for 24 months  following  such date if the date occurs within 60 days
prior or 12 months after a change in control,  or (ii)  continues for the period
following such  termination  date determined by reducing 36 months by the number
of months the Chief  Executive  Officer was employed by the Company  following a
change in control.

         The  Company   amended  its   Executive   Compensation   and   Benefits
Continuation Agreement with Mr. Lynn (the "Employment Agreement") on October 14,
1997. As amended,  the agreement provided,  upon the occurrence of a Termination
Event  (defined  below),  for the  payment of the  equivalent  of 24 months base
salary,  the payment of health insurance  policies for up to 18 months following
the Termination Event, immediate vesting of all stock options not already vested
and the payment of a bonus  (equal to the  fraction  of the current  year worked
multiplied  by the bonus paid for the prior  year).  A  "Termination  Event" was
defined as the involuntary  termination of Mr. Lynn by the Company without cause
or the  termination of employment by Mr. Lynn on account of a material change in
the  business  of the  Company or the  duties of Mr.  Lynn prior to or within 30
months  after a change in control of  Company.  The  Employment  Agreement  also
provided that,  with respect to any  Termination  Event that was also covered by
the Severance Plan, Mr. Lynn would receive compensation and benefits pursuant to
the  Employment  Agreement  only and not  pursuant  to the  Severance  Plan.  In
connection with his departure from the Company on May 18, 1998, Mr. Lynn entered
into a  letter  agreement  with  the  Company  that  modified  the  terms of the
Employment  Agreement as  described in footnote (2) to the Summary  Compensation
Table above.

         In connection with arrangements  relating to the proposed  agreement of
merger between Cortech and BioStar (the "Merger"), which proposal has since been
terminated,  Cortech  entered  into an  agreement  with Mr.  Boran  (the  "Boran
Agreement")  which  provides that the cash benefits  payable under the Severance
Plan would have been paid to Mr. Boran upon the effectiveness of the Merger. The
Boran  Agreement  further  provides that benefits  available under the Severance
Plan would also be paid to Mr. Boran (with cash payments made over the course of
six months) in the event of Mr. Boran's  involuntary  termination in the absence
of the Merger and that  Cortech  would have  employed  Mr.  Boran at his current
salary as a full-time  consultant for the six months following the effectiveness
of the Merger. The Boran Agreement continues to be in full force and effect.

Compensation Committee Interlocks and Insider Participation

         The members of the Company's  Compensation  Committee  during 1997 were
Drs.  Kennedy and Misher and Mr.  Fingerhut.  There were no  interlocks or other
relationships  among the Company's  executive  officers and  directors  that are
required to be disclosed  under  applicable  executive  compensation  disclosure
regulations.

                REPORT TO STOCKHOLDERS ON EXECUTIVE COMPENSATION

         The Compensation  Committee of the Board of Directors (the "Committee")
consisted during 1997 of Drs. Kennedy and Misher, each of whom resigned from the
Board effective July 21, 1998, and Mr.  Fingerhut.  The Committee is responsible
for recommending and administering  the Company's  policies  governing  employee
compensation  and  for  administering  the  Company's  employee  benefit  plans,
including  its  stock  plans.   The  Committee   evaluates  the  performance  of
management,   recommends   compensation   policies   and   levels,   and   makes
recommendations  concerning salaries and incentive compensation.  The full Board
of Directors reviews the Committee's  recommendations regarding the compensation
of the executive officers of the Company.

         It is the Company's  policy generally to qualify  compensation  paid to
executive  officers  for  deductibility  under  Section  162(m) of the  Internal
Revenue Code (the "Code").  Section 162(m) limits the Company to a deduction for
federal income tax purposes of no more than $1 million of  compensation  paid to
certain executive officers in a taxable year.  Compensation above $1 million may
be deducted if it is "performance-based"  compensation within the meaning of the
Code. The Compensation Committee has determined that stock options granted under
the  Company's  1993 Equity  Incentive  Plan with an exercise  price equal to at
least the fair market value of the  Company's  Common Stock on the date of grant
shall  be  treated  as  "performance-based  compensation,"  to  the  extent  the
requirements  of Section 162(m) are otherwise  satisfied and consistent with the
best interests of the Company.  All options granted to executive  officers under
such plan after January 1, 1996 are eligible for treatment as "performance-based
compensation."

Key Elements of Executive Compensation

         The Company's executive compensation program is designed to attract and
retain executives capable of leading the Company to meet its business objectives
and to motivate them to enhance long-term stockholder value. The key elements of
the program are competitive pay and equity incentives.  Annual  compensation for
the Company's  executive officers consists of three elements:  a base salary, an
incentive bonus and stock option grants.

         The Committee makes compensation determinations based upon a subjective
assessment of a variety of factors,  both personal and corporate,  in evaluating
the  performance  of the Company's  executive  officers and making  compensation
decisions.  These factors include,  in order of importance,  the progress of the
Company toward its long-term  objectives,  the individual  contributions of each
officer to the  Company,  and the  compensation  paid by selected  biotechnology
companies to individuals in comparable  positions.  The Committee's  weighing of
these factors in determining the compensation of an individual executive officer
may vary. In awarding  stock  options,  the  Committee  considers the number and
value of an executive officer's outstanding stock options.

         In light of the  Company's  disappointing  test results and the loss of
collaborative  partner support,  the measures presently used by the Committee in
evaluating  the  Company's  progress  are  management's  ability to  effectively
implement the Board of Director's  restructuring and cost-saving policies, which
include  (i)  reducing  the  Company's  work  force,  (ii)  decommissioning  the
Company's laboratories, and (iii) selling the Company's scientific and technical
equipment,  as  well  as  management's  ability  to  efficiently  use  corporate
resources.  Historically,  the Committee has considered,  and where  appropriate
will continue to consider,  (a) the  achievement  and  management of appropriate
collaborative   arrangements  with  larger   pharmaceutical   and  biotechnology
companies  relating  to  the  discovery  and  development  of   commercializable
products,  (b) progress of products under  development in pre-clinical  (animal)
testing,  (c) the effectiveness  with which management  identifies new strategic
alternatives  and  its  responses  to new  information  such as the  results  of
research programs and clinical trials in the context of the identified strategic
alternatives, and (d) the hiring and retention of subordinate officers and other
key employees best capable of accomplishing the foregoing.

         Base Salary. When utilizing comparative data, the Committee attempts to
set  compensation  levels in the  mid-range of  management  compensation  at the
companies  examined.  In December  1996, the  Compensation  Committee set annual
salaries for 1997.  The  Compensation  Committee  reviews  salaries on an annual
basis,  with the annual review for 1998 having  occurred in December 1997. At an
annual review, the Compensation  Committee may increase each executive officer's
salary based on the individual's  contributions  and  responsibilities  over the
prior 12 months and expectations for the next 12 months.
   
         Bonus.  The  Committee  may award bonuses at the end of the fiscal year
based on the Company's ability to meet its corporate and strategic goals and the
individual's  contributions  to those  goals,  if it  deems  such an award to be
appropriate.  Based on management's ability to effectively implement the Board's
restructuring  policies within a relatively  short period of time, the Committee
decided to award cash bonuses for 1997 to certain  officers  and key  employees.
    

         Stock Options.  Long-term  incentives are provided by means of periodic
grants  of  stock  options.   The  Company's  1993  Equity   Incentive  Plan  is
administered  by the  Compensation  Committee.  The  Committee  believes that by
granting executive officers an opportunity to obtain and increase their personal
ownership of Company stock,  the best interests of  stockholders  and executives
will be more closely integrated. The vesting provisions of the option plan serve
to retain  qualified  employees,  providing  continuing  benefits to the Company
beyond those achieved in the year of grant.

Chief Executive Officer Compensation

         Compensation  paid during 1997 to Kenneth R. Lynn, the Company's former
Chief Executive  Officer,  was determined based on a subjective  analysis of the
criteria  described above and reflected the Company's  strategic  challenges for
the coming year,  including its need to significantly  reduce costs and conserve
cash,  while at the same time  pursuing  new  collaborative  relationships  with
larger biotechnology and pharmaceutical  companies, and the desire to compensate
the  chief  executive  officer  in the  mid-range  of  comparable  biotechnology
companies,  based  upon  an  industry  survey  covering  107  biotechnology  and
biopharmaceutical firms with between 51 and 149 employees.

         The foregoing report has been furnished by the  Compensation  Committee
of the Board of Directors and shall not be deemed  incorporated  by reference by
any general  statement  incorporating by reference this proxy statement into any
filing under the Securities Act of 1933 or under the Securities  Exchange Act of
1934, except to the extent the Company specifically  incorporates this report by
reference and shall not otherwise be deemed filed under such Acts.

                                            Respectfully submitted,
                                            Bert Fingerhut


                          STOCK PRICE PERFORMANCE GRAPH

         The following  graph  illustrates a comparison of the cumulative  total
stockholder  return  (change in stock price plus  reinvested  dividends)  of the
Company's Common Stock with the Nasdaq Stock Market (US) (the "Nasdaq US Index")
and the Hambrecht & Quist "Biotechnology Index" (the "H&Q Biotechnology Index").
The  comparisons  in the graph are  required by the SEC and are not  intended to
forecast or be indicative of possible future performance of the Company's Common
Stock.

                               [Performance Graph]

                 12/31/92  12/31/93   12/31/94  12/31/95   12/31/96     12/31/97

Cortech, Inc.    $100.00    127.91      25.29     23.83      13.67         5.53
Nasdaq US Index   100.00    114.80     112.21    158.70     195.19       239.53
H & Q Biotech-    100.00     86.21      81.89    139.30     128.53       130.10
nology Index

         Assumes a $100 investment on December 31, 1992 in each of the Company's
Common Stock, the securities  comprising the Nasdaq US Index, and the securities
comprising the H&Q Biotechnology Index.

                 CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

         In February  1992,  Cortech  entered into a series of  agreements  with
CP-0127 Development  Corporation ("CDC") that govern the development of products
utilizing  Bradycor.  The agreements  grant CDC the right to utilize Bradycor in
the United  States,  Canada and Europe for certain  indications,  while  Cortech
retained  rights to such  products in other parts of the world.  Cortech has the
right to market,  sell and  license  the  technology  licensed to CDC or to sell
products  derived  therefrom and is subject to a royalty  obligation in favor of
CDC.  Cortech  is  currently  seeking a partner to advance  the  development  of
components  covered by the license.  Mr. Fingerhut,  the Company's  Chairman and
Acting Chief Executive Officer, is a director of CDC.

         The Company believes that the foregoing  transactions and relationships
are in its best interests.  As a matter of policy these  transactions  were, and
all future  transactions  between  the Company and its  officers,  directors  or
principal  stockholders  will be,  approved by a majority of the independent and
disinterested  members of the Board of Directors,  on terms no less favorable to
the  Company  than could be  obtained  from  unaffiliated  third  parties and in
connection with bona fide business purposes of the Company.

                                LEGAL PROCEEDINGS

         Biostar Litigation.  On February 27, 1998, a complaint was filed in the
New Castle County,  Delaware Court of Chancery naming the Company, the Company's
directors and BioStar as defendants.  The  complaint,  filed by a stockholder of
the Company, claims to be on behalf of a class of all the Company's stockholders
and contends that the directors of the Company  breached their fiduciary  duties
to the  Company's  stockholders  when they  unanimously  approved  the  proposed
combination with BioStar. The complaint originally sought to enjoin the proposed
combination  with BioStar as well as the operation of the Company's  stockholder
rights plan and sought an order rescinding the proposed combination with BioStar
upon its  consummation as well as compensatory  damages and costs. The complaint
was amended  following  termination  of the  Biostar  merger to seek to force an
auction of the Company and other  relief.  The Company  believes that the claims
are without merit and intends to vigorously  defend against this suit.  Although
there can be no  assurances in this regard,  the Company  believes that the suit
will have no  material  adverse  effect on the  Company  because the Company (i)
believes  that  the  claimant  will  not  prevail  on the  merits,  and (ii) has
insurance  which it believes will cover the cost of defending this claim (except
for a $75,000 deductible amount.

         AVF  Litigation.  Because the  proposed  combination  with  Biostar was
terminated  on May 7, 1998,  the annual  meeting of the Company  scheduled to be
held in conjunction with the stockholder vote on the Biostar transaction was not
held.  Under Delaware law, any stockholder can seek a court action to require an
annual  meeting if a company  has not held an annual  meeting for a period of 13
months.  This period  expired on June 28, 1998,  and, on the following  day, AVF
filed an action in the Court of  Chancery of the State of Delaware to compel the
Company to hold an annual  meeting of  stockholders  immediately.  Pursuant to a
stipulation order entered into by the Company and AVF, and approved by the Court
on July 16, 1998, the Company and AVF agreed and  stipulated  that the Company's
annual  meeting  would be held on September 4, 1998 with the record date set for
July 10, 1998.

                              STOCKHOLDER PROPOSALS

         To be considered for inclusion in the proxy statement for  presentation
at the Annual Meeting of Stockholders to be held in 1999, a stockholder proposal
must be received  at the  offices of the  Company,  6850 N.  Broadway,  Suite G,
Denver, CO 80221 not later than April 10, 1999.


                                  SOLICITATION

        The  Company  will bear the  entire  cost of  solicitation  of  proxies,
including preparation,  assembly,  printing and mailing of this proxy statement,
the proxy and any additional  information  furnished to stockholders.  Copies of
solicitation materials will be furnished to banks, brokerage houses, fiduciaries
and custodians  holding in their names shares of Common Stock beneficially owned
by others to  forward to such  beneficial  owners.  The  Company  may  reimburse
persons  representing  beneficial  owners  of Common  Stock  for their  costs of
forwarding   solicitation   materials  to  such  beneficial   owners.   Original
solicitation of proxies by mail may be  supplemented  by telephone,  telegram or
personal  solicitation by directors,  officers or other regular employees of the
Company or, at the Company's  request,  D.F. King & Co.,  Inc., 77 Water Street,
New York, New York 10008-4495 ("D.F.  King").  D.F. King has advised the Company
that  approximately 25 D.F. King employees will provide assistance in connection
with the  solicitation.  No additional  compensation  will be paid to directors,
officers or other  regular  employees for such  services,  but D.F. King will be
paid a fee,  estimated to be up to  approximately  $47,500 (of which  $17,500 is
contingent  upon the result of the proxy contest) plus reasonable  expenses,  to
assist in the  solicitation  of proxies.  The Company  estimates  that the total
amount  of  expenses  to be  incurred  by  it  in  connection  with  this  proxy
solicitation will be $135,000, $10,000 of which has been incurred to date.

                                 INDEMNIFICATION

         The Company's Certificate and Bylaws provide,  among other things, that
the Company will indemnify each officer or director, under the circumstances and
to the extent provided for therein, for expenses,  damages, judgments, fines and
settlements  he may be required to pay in actions or  proceedings to which he is
or may be made a party by reason of his position as a director, officer or other
agent of the Company,  and otherwise to the full extent permitted under Delaware
law.

             SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE

         Section  16(a) of the  Securities  Exchange  Act of 1934,  as  amended,
requires the Company's  directors,  executive officers,  and any persons holding
more than 10% of the Company's Common Stock to file initial reports of ownership
and reports of change in ownership of the  Company's  Common Stock with the SEC.
Officers,  directors and greater than ten percent  stockholders  are required by
SEC  regulation  to furnish the Company  with copies of all Section  16(a) forms
they file.

         To the Company's  knowledge,  based solely on a review of the copies of
such reports furnished to the Company and written  representations that no other
reports were  required,  during the fiscal year ended  December  31,  1997,  all
Section 16(a) filing  requirements  applicable  to its  officers,  directors and
greater than ten percent beneficial owners were complied with.

                                  OTHER MATTERS

         The  Board  of  Directors  knows  of no  other  business  that  will be
presented  at the Annual  Meeting.  If any other  matters are  properly  brought
before the Annual Meeting, it is intended that proxies in the enclosed form will
be voted in accordance with the judgment of the persons voting the proxies.

         Any  stockholder  or  stockholder's  representative  who,  because of a
disability,  may need special assistance or accommodation to allow him or her to
participate  at  the  Annual  Meeting  may  request  reasonable   assistance  or
accommodation  from the Company by contacting  Cortech,  Inc., 6850 N. Broadway,
Suite G, Denver,  CO 80221,  (303) 650-1200.  To provide the Company  sufficient
time to arrange for reasonable  assistance or  accommodation,  please submit all
requests by August 25, 1998.

         If you have any questions  concerning  this proxy  solicitation  of the
procedures to execute and deliver a proxy, please contact D.F. King at:

                              D.F. King & Co., Inc.
                                 77 Water Street
                          New York, New York 10005-4495
                             (212) 269-5550 collect
                            (800) 848-3051 toll free

         Whether you intend to be present at the Annual  Meeting or not, we urge
you to return your signed WHITE proxy card promptly.

                                 By order of the Board of Directors


                                 Bert Fingerhut
                                 Chairman


<PAGE>


                                  CORTECH, INC.
                    PROXY SOLICITED BY THE BOARD OF DIRECTORS
                     FOR THE ANNUAL MEETING OF STOCKHOLDERS
                         TO BE HELD ON SEPTEMBER 4, 1998

         The undersigned hereby appoints Bert Fingerhut, Diarmuid Boran and John
Cheronis,  M.D., and each of them, as attorneys and proxies of the  undersigned,
with full power of  substitution,  to vote all of the shares of Common  Stock of
Cortech,  Inc. (the "Company")  which the undersigned may be entitled to vote at
the Annual Meeting of  Stockholders of the Company to be held at the Renaissance
Hotel,  3801 Quebec Street,  Denver,  Colorado on Friday,  September 4, 1998, at
9:00 a.m.,  local  time,  and at any and all  postponements,  continuations  and
adjournments  thereof,  with all powers that the  undersigned  would  possess if
personally  present,  upon  and in  respect  of  the  following  matters  and in
accordance with the following  instructions,  with discretionary authority as to
any and all other matters that may properly come before the meeting.

         UNLESS A CONTRARY DIRECTION IS INDICATED,  THIS PROXY WILL BE VOTED FOR
THE NOMINEES LISTED IN PROPOSAL 1, FOR PROPOSALS 2, 3 AND 4 AND AGAINST PROPOSAL
5, ALL AS MORE  SPECIFICALLY  DESCRIBED  IN THE  PROXY  STATEMENT.  IF  SPECIFIC
INSTRUCTIONS ARE INDICATED, THIS PROXY WILL BE VOTED IN ACCORDANCE THEREWITH.

PROPOSAL 1: ELECTION OF DIRECTORS

         The Board of  Directors  recommends  a vote FOR the  Nominee(s)  listed
below.

o FOR the nominee(s) listed below          o    WITHHOLD AUTHORITY to vote for  
  (except as marked to the contrary below).     the nominee(s) listed below.

         NOMINEE:

   
         __________________________  (Class I  Director)
         __________________________  (Class I  Director)
         __________________________  (Class I  Director)*
         __________________________  (Class III Director)*
    

- ----------------
* Nominated for election  solely in the event Proposal 5 to increase the size of
  the Board, which is opposed by the Board of Directors, is approved.


TO WITHHOLD AUTHORITY TO VOTE FOR ANY NOMINEE WRITE SUCH NOMINEE'S NAME BELOW

- ---------------------------------------------------

(CONTINUED AND TO BE SIGNED ON OTHER SIDE)


<PAGE>




   
PROPOSAL  2:  To  approve  an  amendment  to  the   Company's   Certificate   of
Incorporation that provides for a one-for-ten reverse stock split.
    
o FOR         o AGAINST        o  ABSTAIN

The Board of Directors recommends a vote FOR Proposal 2.

PROPOSAL  3: To amend  Article IX,  Section 1 of the  Company's  Certificate  of
Incorporation  to provide that the number of directors shall be set by the Board
of Directors.

o?FOR         o AGAINST        o  ABSTAIN

The Board of Directors recommends a vote FOR Proposal 3.

PROPOSAL  4: To ratify  the  selection  of Arthur  Andersen  LLP as  independent
auditors of the Company for its fiscal year ending December 31, 1998.

o FOR         o AGAINST        o  ABSTAIN

The Board of Directors recommends a vote FOR Proposal 4.

   
PROPOSAL 5: To amend Article 3, Section 3.1 of the  Company's  Bylaws to set the
number of directors to serve on the Board of Directors at seven.
    

o FOR         o AGAINST        o  ABSTAIN

The Board of Directors recommends a vote AGAINST Proposal 5.

         DATE: _________________________, 1998

         ------------------------------------
         SIGNATURE(S)

         ------------------------------------
         TITLE (IF APPLICABLE)

         Please  sign  exactly  as your  name  appears  hereon.  If the stock is
         registered  in the  names of two or more  persons,  each  should  sign.
         Executors,  administrators,  trustees,  guardians and attorneys-in-fact
         should add their titles.  If signer is a corporation,  please give full
         corporate name and have a duly authorized  officer sign, stating title.
         If  signer  is a  partnership,  please  sign  in  partnership  name  by
         authorized person.

PLEASE  SIGN,  DATE AND PROMPTLY  RETURN THIS PROXY CARD IN THE ENCLOSED  RETURN
ENVELOPE WHICH IS POSTAGE PREPAID IF MAILED IN THE UNITED STATES.


<PAGE>


                      BARTLIT BECK HERMAN PALENCHAR & SCOTT
                             The Kittredge Building
                              511 Sixteenth Street
                                Denver, CO 80202

   
August 6, 1998
    



Securities and Exchange Commission
Judiciary Plaza
450 Fifth Street, N.W.
Washington, D.C.  20549

         Re:      Cortech, Inc.

Dear Sir or Madam:

         On behalf of Cortech, Inc., a Delaware corporation (the "Company"),  we
hereby  electronically  transmit,  pursuant to Regulation S-T promulgated by the
Securities and Exchange  Commission,  the revised preliminary Proxy Statement of
the Company in respect of its annual  meeting to be held on  September  4, 1998.
Asset Value Fund Limited Partnership,  a stockholder of the Company, has filed a
definitive proxy statement in opposition to the solicitation by the Company.

         Please contact the  undersigned at (303) 592-3175 or Thomas R. Stephens
of this firm at (303) 592-3144  should you require  further  information or have
any additional questions.

                                          Very truly yours,

                                          /s/ Polly S. Swartzfager

                                         Polly S. Swartzfager
                                         (Admitted in New York;
                                         application pending in Colorado)



PSS/kmv




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