ONCOGENE SCIENCE INC
S-3MEF, 1996-03-14
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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<PAGE>   1
 
     AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON MARCH 13, 1996
                                                        REGISTRATION NO.
- - - --------------------------------------------------------------------------------
- - - --------------------------------------------------------------------------------
 
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                            ------------------------
 
                                    FORM S-3
                             REGISTRATION STATEMENT
                                     UNDER
 
                           THE SECURITIES ACT OF 1933
                            ------------------------
                             ONCOGENE SCIENCE, INC.
             (EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)
 
<TABLE>
<S>                                                  <C>
                     DELAWARE                                            13-3159796
         (STATE OR OTHER JURISDICTION OF                              (I.R.S. EMPLOYER
          INCORPORATION OR ORGANIZATION)                            IDENTIFICATION NO.)
</TABLE>
 
        106 CHARLES LINDBERGH BLVD., UNIONDALE, NY 11553, (516) 222-0023
    (ADDRESS, INCLUDING ZIP CODE, AND TELEPHONE NUMBER, INCLUDING AREA CODE,
                  OF REGISTRANT'S PRINCIPAL EXECUTIVE OFFICES)
 
                             ROBERT L. VAN NOSTRAND
                             ONCOGENE SCIENCE, INC.
                          106 CHARLES LINDBERGH BLVD.
                           UNIONDALE, NEW YORK 11553
                                 (516) 222-0023
           (NAME, ADDRESS, INCLUDING ZIP CODE, AND TELEPHONE NUMBER,
                   INCLUDING AREA CODE, OF AGENT FOR SERVICE)
 
                        COPIES OF ALL COMMUNICATIONS TO:
 
<TABLE>
<S>                                                  <C>
         SPENCER W. FRANCK, JR., ESQUIRE                          LESLIE E. DAVIS, ESQUIRE
            SAUL, EWING, REMICK & SAUL                           TESTA, HURWITZ & THIBEAULT
             3800 CENTRE SQUARE WEST                                  125 HIGH STREET
         PHILADELPHIA, PENNSYLVANIA 19102                       BOSTON, MASSACHUSETTS 02110
                  (215) 972-7777                                       (617) 248-7000
</TABLE>
 
     APPROXIMATE DATE OF COMMENCEMENT OF PROPOSED SALE TO THE PUBLIC:  As soon
as practicable after the effective date of this Registration Statement.
 
     If the only securities being registered on this Form are being offered
pursuant to dividend or interest reinvestment plans, please check the following
box. / /
 
     If any of the securities being registered on this Form are to be offered on
a delayed or continuous basis pursuant to Rule 415 under the Securities Act of
1933, other than securities offered only in connection with dividend or interest
reinvestment plans, check the following box. / /
 
     If this Form is filed to register additional securities for an offering
pursuant to Rule 462(b) under the Securities Act, please check the following box
and list the Securities Act registration statement number of the earlier
effective registration statement for the same offering. /X/
 
     If this Form is a post-effective amendment filed pursuant to Rule 462(c)
under the Securities Act, check the following box and list the Securities Act
registration statement number of the earlier effective registration statement
for the same offering. / /
 
     If delivery of the prospectus is expected to be made pursuant to Rule 434,
please check the following box. /X/
 
                        CALCULATION OF REGISTRATION FEE
- - - --------------------------------------------------------------------------------
 
<TABLE>
<S>                               <C>               <C>               <C>               <C>
- - - ----------------------------------------------------------------------------------------------------------
                                                     PROPOSED MAXIMUM  PROPOSED MAXIMUM
      TITLE OF SECURITIES TO         AMOUNT TO BE     OFFERING PRICE      AGGREGATE         AMOUNT OF
          BE REGISTERED             REGISTERED(1)      PER SHARE(2)     OFFERING PRICE   REGISTRATION FEE
- - - ----------------------------------------------------------------------------------------------------------
Common Stock, Par Value $0.01 Per
  Share...........................   373,750 shares       $9.50           $3,550,625          $1,225
- - - ----------------------------------------------------------------------------------------------------------
- - - ----------------------------------------------------------------------------------------------------------
</TABLE>
 
(1) Includes 48,750 shares subject to an over-allotment option granted to the
    Underwriters.
 
(2) Estimated solely for the purpose of calculating the registration fee, based
    on the average of the high and low prices for the Common Stock as reported
    on the Nasdaq National Market on March 8, 1996, in accordance with Rule
    457(c) under the Securities Act of 1933.
- - - --------------------------------------------------------------------------------
- - - --------------------------------------------------------------------------------
<PAGE>   2
 
               INCORPORATION OF CERTAIN INFORMATION BY REFERENCE
 
     The information in the Registration Statement filed by Oncogene Science,
Inc. with the Securities and Exchange Commission (File No. 333-937) pursuant to
the Securities Act of 1933, as amended, is incorporated by reference into this
Registration Statement. This registration statement is being filed pursuant to
Rule 462(b) to register an additional 373,750 shares of Common Stock.
<PAGE>   3
 
                                   SIGNATURES
 
     Pursuant to the requirements of the Securities Act of 1933, the Registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-3 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of Uniondale, State of New York, on March 13, 1996.
 
                                          ONCOGENE SCIENCE, INC.
 
                                          By: /s/  GARY E. FRASHIER
                                            ------------------------------------
                                            Gary E. Frashier,
                                            Chief Executive Officer
 
                               POWER OF ATTORNEY
 
     KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears
below hereby makes, constitutes and appoints Gary E. Frashier and Robert L. Van
Nostrand, and each of them, with full power to act without the other, his true
and lawful attorney-in-fact and agent, with full power of substitution and
resubstitution, for him and in his name, place and stead, in any and all
capacities to sign any and all amendments to this Registration Statement,
including posteffective amendments, and to file the same, with all exhibits
thereto, and other documents in connection therewith, with the Securities and
Exchange Commission, granting unto said attorneys-in-fact and agents, and each
of them, full power and authority to do and perform each and every act and thing
requisite or necessary to be done in connection therewith, as fully to all
intents and purposes as he might or could do in person, hereby ratifying and
confirming all that said attorneys-in-fact and agents or any of them, or any
substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
 
     Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed by the following persons in the
capacities and on the dates indicated.
 
<TABLE>
<CAPTION>
              SIGNATURE                               TITLE                         DATE
- - - -------------------------------------  ------------------------------------    ---------------
<S>                                    <C>                                     <C>
/s/  GARY E. FRASHIER                  Chief Executive Officer and Director     March 13, 1996
- - - -------------------------------------
Gary E. Frashier

/s/  STEVE M. PELTZMAN                 President, Chief Operating Officer       March 13, 1996
- - - -------------------------------------  and Director
Steve M. Peltzman

/s/  J. GORDON FOULKES                 Vice President, Chief Scientific         March 13, 1996
- - - -------------------------------------  Officer and Director
J. Gordon Foulkes

/s/  ROBERT L. VAN NOSTRAND            Vice President, Finance and              March 13, 1996
- - - -------------------------------------  Administration (Principal Financial
Robert L. Van Nostrand                 and Accounting Officer)

/s/  G. MORGAN BROWNE                  Director                                 March 13, 1996
- - - -------------------------------------
G. Morgan Browne

/s/  JOHN H. FRENCH, II                Director                                 March 13, 1996
- - - -------------------------------------
John H. French, II
</TABLE>
<PAGE>   4
 
<TABLE>
<CAPTION>
              SIGNATURE                               TITLE                         DATE
- - - -------------------------------------  ------------------------------------    ---------------
<S>                                    <C>                                     <C>
/s/  EDWIN A. GEE, PH.D.               Director                                 March 13, 1996
- - - -------------------------------------
Edwin A. Gee, Ph.D.

/s/  WALTER M. LOVENBERG, PH.D.        Director                                 March 13, 1996
- - - -------------------------------------
Walter M. Lovenberg

/s/  WALTER M. MILLER                  Director                                 March 13, 1996
- - - -------------------------------------
Walter M. Miller

/s/  GARY TAKATA                       Director                                 March 13, 1996
- - - -------------------------------------
Gary Takata

/s/  JOHN P. WHITE                     Director                                 March 13, 1996
- - - -------------------------------------
John P. White
</TABLE>
<PAGE>   5
 
                                 EXHIBIT INDEX
 
<TABLE>
<CAPTION>
                                                                                  SEQUENTIAL
EXHIBIT NO.                               EXHIBIT                                 PAGE NUMBER
- - - ------------  ----------------------------------------------------------------    -----------
<C>           <S>                                                                 <C>
     5.1      Opinion of Saul, Ewing, Remick & Saul as to the legality of the
              securities registered hereunder
    23.1      Consent of KPMG Peat Marwick LLP
    23.2      Consent of Saul, Ewing, Remick & Saul (included in Exhibit 5.1)
</TABLE>

<PAGE>   1
                                                                     Exhibit 5.1


                                 LAW OFFICES OF
                           SAUL, EWING, REMICK & SAUL

HARRISBURG, PENNSYLVANIA      3800 CENTRE SQUARE WEST       PRINCETON NEW JERSEY
MALVERN, PENNSYLVANIA         PHILADELPHIA, PA 19102        WESTMONT, NEW JERSEY
NEW YORK, NEW YORK                                          WILMINGTON, DELAWARE

                                 (215) 972-7777

                              Fax: (215) 972-7725
                        Internet Email: [email protected]
                      World Wide Web: http://www.saul.com

                                                                  March 13, 1996

Oncogene Science, Inc.
106 Charles Lindbergh Blvd.
Uniondale, NY 11553

Gentlemen:

        We refer to the Registration Statement on Form S-3 (the "Registration 
Statement") of Oncogene Science, Inc., a Delaware corporation (the "Company"), 
to be filed with the Securities and Exchange Commission covering the 
registration under the Securities Act of 1933, as amended (the "Securities 
Act"), of 373,500 shares of common stock, par value $.01 per share, of the 
Company (the "Shares").

        We have examined the Registration Statement, the Certificate of 
Incorporation and By-laws of the Company and such records, certificates and 
other documents as we have considered necessary or appropriate for the purposes 
of this Opinion.

        Based on the foregoing, it is our opinion that:

        1. the Company is duly organized, validly existing and in good 
standing under the laws of State of Delaware; and

        2. the Shares to be issued in accordance with the terms described in 
the Registration Statement have been duly authorized and, when issued in 
accordance with the terms described in the Registration Statement, will be 
validly issued, fully paid and non-assessable.

        We hereby consent to use of our name in the Registration Statement as 
counsel who will pass upon the legality of the Shares for the Company and as 
having prepared this Opinion as an exhibit to the Registration Statement. In 
giving the foregoing consent, we do not thereby admit that we are in the 
category of persons whose consent is required under Section 7 of the Securities 
Act or the rules and regulations of the Securities and Exchange Commission 
thereunder.

                                                Very truly yours,


                                                SAUL, EWING, REMICK & SAUL

<PAGE>   1

                                                                   Exhibit 23.1


                         INDEPENDENT AUDITORS' CONSENT


The Board of Directors
Oncogene Science, Inc.:


        We consent to the use of our report included herein and incorporated
herein by reference and to the reference to our firm under the heading
"Experts" in the prospectus.

                                        KPMG PEAT MARWICK LLP

Jericho, New York
March 12, 1996



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