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<PAGE> 1 EXHIBIT 23.1 CONSENT OF INDEPENDENT AUDITORS The Board of Directors OSI Pharmaceuticals, Inc. We consent to the use of our report dated December 22, 1999, incorporated herein by reference, and to the reference to our firm under the heading "Experts" in the prospectus. /s/ KPMG LLP Melville, New York June 20, 2000
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