ALPHARMA INC
10-Q, 1999-11-02
PHARMACEUTICAL PREPARATIONS
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                          Page 24 of 32



                          UNITED STATES
               SECURITIES AND EXCHANGE COMMISSION
                     WASHINGTON, D.C. 20549


                            FORM 10-Q


      Quarterly Report Pursuant To Section 13 or 15 (d) of
               the Securities Exchange Act of 1934


For quarter ended                  Commission file number 1-8593
September 30, 1999

                          Alpharma Inc.
     (Exact name of registrant as specified in its charter)

           Delaware                          22-2095212
 (State of Incorporation)    (I.R.S. Employer Identification No.)

       One Executive Drive, Fort Lee, New Jersey    07024
       (Address of principal executive offices)   Zip Code

                         (201) 947-7774
       (Registrant's Telephone Number Including Area Code)

      Indicate by check mark whether the registrant (1) has filed
all  reports required to be filed by Section 13 or 15 (d) of  the
Securities  Exchange Act of 1934 during the preceding  12  months
(or  for such shorter period that the registrant was required  to
file such reports), and (2) has been subject to such requirements
for the past 90 days.

                       YES    X         NO

      Indicate  the number of shares outstanding of each  of  the
Registrant's classes of common stock as of October 25, 1999.

     Class A Common Stock, $.20 par value - 18,089,649 shares;
     Class B Common Stock, $.20 par value -  9,500,000 shares


                         ALPHARMA INC.

                             INDEX




                                                       Page No.

PART I.  FINANCIAL INFORMATION


   Item 1.  Financial Statements

     Consolidated Condensed Balance Sheet as of
     September 30, 1999 and December 31, 1998               3

     Consolidated Statement of Income for the
     Three and Nine Months Ended September 30,
     1999 and 1998                                           4

     Consolidated Condensed Statement of Cash
     Flows for the Nine Months Ended September 30,
     1999 and 1998                                           5

     Notes to Consolidated Condensed Financial
     Statements                                              6-17


   Item 2.  Management's Discussion and Analysis
            of Financial Condition and Results of
            Operations                                    18-29

   Item 3. Quantitative and Qualitative Disclosures       29-30
           about Market Risk

PART II.  OTHER INFORMATION

   Item 1. Legal proceedings                              30-31

   Item 5. Other Information                              31

   Item 6. Exhibits and reports on Form 8-K               31

   Signatures                                             32

                 ALPHARMA INC. AND SUBSIDIARIES
              CONSOLIDATED CONDENSED BALANCE SHEET
                    (In thousands of dollars)
                           (Unaudited)

                                    September 30,   December 31,
                                        1999           1998
ASSETS
Current assets:
  Cash and cash equivalents           $ 23,305       $ 14,414
  Accounts receivable, net             192,921        169,744
  Inventories                          155,958        138,318
  Prepaid expenses and other            12,983         13,008
      Total current assets             385,167        335,484

Property, plant and equipment, net     246,244        244,132
Intangible assets, net                 502,120        315,709
Other assets and deferred charges       38,210         13,611
      Total assets                  $1,171,741       $908,936

LIABILITIES AND STOCKHOLDERS' EQUITY
Current liabilities:
  Current portion of long-term debt $    4,211       $ 12,053
  Short-term debt                       27,700         41,921
  Accounts payable and accrued
      liabilities                      138,985        105,679
  Accrued and deferred income taxes     10,719         10,784
      Total current liabilities        181,615        170,437

  Long-term debt:
   Senior                              282,622        236,184
   Convertible subordinated notes,
   including $67,850 to related
   party                               365,009        192,850
  Deferred income taxes                 31,880         31,846
  Other non-current liabilities         12,206         10,340

Stockholders' equity:
  Class A Common Stock                   3,673          3,551
  Class B Common Stock                   1,900          1,900
  Additional paid-in-capital           235,079        219,306
  Accumulated other comprehensive
      loss                            (15,453)        (7,943)
  Retained earnings                     79,394         56,649
  Treasury stock, at cost              (6,184)        (6,184)
      Total stockholders' equity       298,409        267,279
        Total liabilities and
          stockholders' equity      $1,171,741       $908,936

           The accompanying notes are an integral part
       of the consolidated condensed financial statements.
                      ALPHARMA INC. AND SUBSIDIARIES
                     CONSOLIDATED STATEMENT OF INCOME
                  (In thousands, except per share data)
                              (Unaudited)


                             Three Months Ended    Nine Months Ended
                               September 30,         September 30,

                               1999      1998       1999      1998

Total revenue               $203,131  $164,337     $523,729 $430,412

  Cost of sales             108,838     97,642      287,233  251,138

Gross profit                 94,293     66,695      236,496  179,274

  Selling, general and
   administrative expenses   64,664     46,801      167,478  134,634

Operating income             29,629     19,894       69,018   44,640

  Interest expense          (11,257)    (7,454)     (27,580) (18,433)

  Other income (expense),     (673)       (377)         248     (195)
net

Income before provision for
 income taxes                17,699      12,063      41,686   26,012

  Provision for income        6,436       4,512      15,215   10,754
taxes

Net income                  $11,263    $  7,551    $ 26,471 $ 15,258

Earnings per common share:
  Basic                      $   .41   $   .30    $    .96  $   .60
  Diluted                    $   .38   $   .28    $    .93  $   .59

Dividends per common share   $  .045   $ .045     $   .135  $  .135








               The accompanying notes are an integral part
           of the consolidated condensed financial statements.
                    ALPHARMA INC. AND SUBSIDIARIES
            CONSOLIDATED CONDENSED STATEMENT OF CASH FLOWS
                       (In thousands of dollars)
                              (Unaudited)
                                                   Nine Months Ended
                                                     September 30,
                                                    1999        1998
Operating Activities:
  Net income                                      $ 26,471   $  15,258
  Adjustments to reconcile net
   income to net cash provided
   by operating activities:
   Depreciation and amortization                    35,952      27,250
   Purchased in-process research & development        --         2,081
   Interest accretion on long-term debt              2,159         --
  Changes in assets and liabilities,
   net of effects from business
   acquisitions:
     (Increase) in accounts receivable              (8,029)     (3,699)
     (Increase)decrease in inventories             (13,891)      2,299
     Increase in accounts payable, accrued
       expenses and taxes payable                    1,859       3,094
     Other, net                                      2,769       5,964
       Net cash provided by
         operating activities                       47,290      52,247

Investing Activities:
  Capital expenditures                             (23,332)    (20,347)
 Loans to Ascent Pediatrics                         (7,000)
 Purchase of businesses, net of cash acquired     (203,408)   (197,044)
     Net cash used in investing activities        (233,740)   (217,391)

Financing Activities:
  Dividends paid                                    (3,726)     (3,433)
  Proceeds from sale of convertible
   subordinated notes                              170,000     192,850
  Proceeds from senior long-term debt              317,000     187,522
  Reduction of senior long-term debt              (279,619)   (182,494)
  Net repayments under lines of credit             (15,609)    (22,649)
  Payments for debt issuance costs                  (8,757)     (4,175)
  Proceeds from issuance of common stock            15,895       2,682
          Net cash provided by
            financing activities                   195,184     170,303

Exchange Rate Changes:
  Effect of exchange rate changes
    on cash                                           (965)        498
  Income tax effect of exchange rate
    changes on intercompany advances                 1,122        (801)
     Net cash flows from exchange
               rate changes                            157        (303)

Increase in cash                                     8,891       4,856
Cash and cash equivalents at
  beginning of year                                 14,414      10,997
Cash and cash equivalents at
  end of period                                   $ 23,305   $  15,853

              The accompanying notes are an integral part
          of the consolidated condensed financial statements.




1.   General

      The  accompanying  consolidated condensed  financial  statements
include   all   adjustments  (consisting  only  of  normal   recurring
accruals)   which  are,  in  the  opinion  of  management,  considered
necessary  for  a  fair presentation of the results  for  the  periods
presented.   These   financial   statements   should   be   read    in
conjunction   with   the   consolidated   financial   statements    of
Alpharma  Inc.  and  Subsidiaries  included  in  the  Company's   1998
Annual  Report  on  Form  10-K. The reported  results  for  the  three
and   nine   month   periods  ended  September  30,   1999   are   not
necessarily  indicative of the results to be  expected  for  the  full
year.

2.   Inventories

     Inventories consist of the following:

                                 September 30,  December 31,
                                     1999          1998

     Finished product            $ 88,104       $ 68,834
     Work-in-process               28,446         25,751
     Raw materials                 39,408         43,733
                                 $155,958       $138,318

3.   Long-Term Debt

       In   January  1999,  the  Company  signed  a  $300,000   credit
agreement  ("1999  Credit  Facility")  with  a  consortium  of   banks
arranged  by  the  Union  Bank of Norway, Den  norske  Bank  A.S.  and
Summit  Bank.  The  agreement  replaced  the  prior  revolving  credit
facility   and  a  U.S.  short-term  credit  facility  and   increased
overall  credit  availability.  The prior  revolving  credit  facility
was   repaid   in  February  1999  by  drawing  on  the  1999   Credit
Facility.

      The  1999  Credit  Facility provides  for  (i)  a  $100,000  six
year  Term  Loan;  and (ii) a revolving credit agreement  of  $200,000
with  an  initial  term  of  five years with  two  possible  one  year
extensions.   The   1999   Credit  Facility  has   several   financial
covenants,  including  an  interest  coverage  ratio,  total  debt  to
earnings   before  interest,  taxes,  depreciation  and   amortization
("EBITDA"),  and  equity  to  total  asset  ratio.  Interest  on   the
facility  will  be  at the LIBOR rate with a margin of  between  .875%
and   1.6625%  depending  on  the  ratio  of  total  debt  to  EBITDA.
Margins   can  increase  based  on  the  ratio  of  equity  to   total
assets.

      Primarily  as  a  result  of the Company's  acquisition  of  the
Isis  Group,  the  equity to total asset ratio at June  30,  1999  was
24.5%.  The  ratio  falling  below 25% required  an  increase  in  the
margin  on  debt  outstanding  under  the  1999  Credit  Agreement  of
 .75%   (2.25%  aggregate  margin)  beginning  August  18,   1999   and
required  the  Company  to achieve a minimum  25%  ratio  by  December
18,  1999.  The  equity  to total asset ratio at  September  30,  1999
was  25.5%.  The  margin increase will be rescinded  effective  on  or
about November 2, 1999.

      In  June  1999,  the  Company issued $170,000  principal  amount
of  3.0%  Convertible  Senior Subordinated Notes  due  2006  (the  "06
Notes").  The  06  Notes  will pay cash  interest  of  3%  per  annum,
calculated  on  the  initial  principal  amount  of  the  Notes.   The
Notes  will  mature  on June 1, 2006 at a price  of  134.104%  of  the
initial  principal  amount. The payment of  the  principal  amount  of
the  Notes  at  maturity  (or earlier, if the Notes  are  redeemed  by
the  Company  prior  to maturity), together with  cash  interest  paid
over  the  term  of  the  Notes,  will  yield  investors  6.875%   per
annum.  The  interest  accrued but which will not  be  paid  prior  to
maturity  (3.875%  per annum) is reflected as long-term  debt  in  the
accounts  of  the  Company.  The  06  Notes  are  redeemable  by   the
Company after June 16, 2002.

      The  06  Notes  are convertible at any time prior  to  maturity,
unless  previously  redeemed, into 31.1429  shares  of  the  Company's
Class   A   Common   stock  per  one  thousand  dollars   of   initial
principal  amount  of  06  Notes. This ratio  results  in  an  initial
conversion  price  of  $32.11 per share. The  number  of  shares  into
which  a  06  Note  is  convertible  will  not  be  adjusted  for  the
accretion of principal or for accrued interest.

      The  net  proceeds  from the offering of approximately  $164,000
were  used  to  retire outstanding senior long-term  debt  principally
outstanding   under  the  1999  Credit  Facility.  This  created   the
capacity   under   the   1999   Credit   Facility   to   finance   the
acquisition of Isis Pharma in the second quarter. (See Note 4.)


Long-term debt consists of the following:
                                          September 30, December 31,
                                               1999          1998
Senior debt:
 U.S. Dollar Denominated:
  1999 Revolving Credit Facility           $230,000         -
   (7.6 - 8.0%)
       Prior Revolving Credit Facility                   $180,000
       (6.6 - 7.0%)                           -
  A/S Eksportfinans                           -             7,200
  Industrial Development Revenue Bonds:
   Baltimore County, Maryland
     (7.25%)                                  3,930         4,565
     (6.875%)                                 1,200         1,200
   Lincoln County, NC                         4,000         4,500
  Other, U.S.                                   202           504

 Denominated in Other Currencies:
       Mortgage notes payable (NOK)          40,413        42,224
  Bank and agency development loans           7,074         7,991
(NOK)
  Other, foreign                                14             53
 Total senior debt                          286,833       248,237

Subordinated debt:
 5.75% Convertible Subordinated Notes
due 2005                                    125,000        125,000
 5.75% Convertible Subordinated
       Note due 2005 - Industrier Note      67,850         67,850
    3% Convertible Senior Subordinated
       Notes due 2006 (6.875% yield),
       including interest accretion         172,159           -

 Total subordinated debt                    365,009        192,850

  Total long-term debt                      651,842       441,087
  Less, current maturities                   4,211         12,053
                                           $647,631      $429,034

4.   Business Acquisitions

      All  acquisitions  discussed below  are  accounted  for  in
accordance with the purchase method.

Cox:

      On  May  7,  1998, the Company's IPD acquired  all  of  the
capital  stock  of  Cox  Investments Ltd. and  its  wholly  owned
subsidiary,  Arthur H. Cox and Co., Ltd. and all of  the  capital
stock  of  certain  related marketing subsidiaries  ("Cox")  from
Hoechst  AG for a total purchase price including direct costs  of
the  acquisition of approximately $198,000. Cox's operations  are
included  in IPD and are located primarily in the United  Kingdom
with  distribution  operations located  in  Scandinavia  and  the
Netherlands.  Cox  is a generic pharmaceutical  manufacturer  and
marketer  of tablets, capsules, suppositories, liquids, ointments
and creams.

      The  fair  value  of  the assets acquired  and  liabilities
assumed and the results of Cox's operations are included  in  the
Company's  consolidated  financial statements  beginning  on  the
acquisition  date,  May 7, 1998. The Company  is  amortizing  the
acquired  goodwill (approximately $160,000) over 35  years  using
the straight line method.

Jumer:

      On  April 16, 1999, the Company's IPD acquired the  generic
pharmaceutical  business  Jumer  Laboratories  SARL  and  related
companies  of  the Cherqui group ("Jumer") in Paris,  France  for
approximately  $26,400,  which includes the  assumption  of  debt
which was repaid subsequent to closing. The acquisition consisted
of products, trademarks and registrations.

      The  preliminary  fair  value of the  assets  acquired  and
liabilities  assumed  and the results of Jumer's  operations  are
included  in  the  Company's  consolidated  financial  statements
beginning on the acquisition date, April 16, 1999. The Company is
amortizing  the  acquired  intangibles  and  goodwill  based   on
preliminary  estimates of lives generally over an average  of  15
years using the straight line method.

Isis:

      Effective June 15, 1999, the Company's IPD acquired all  of
the  capital  stock of Isis Pharma GmbH and its subsidiary,  Isis
Puren  ("Isis") from Schwarz Pharma AG for approximately $153,000
in  cash,  and a further purchase price adjustment equal  to  any
increase (or decrease) in the net assets of Isis from January  1,
1999  to  the  date of acquisition. Isis operates a  generic  and
branded  pharmaceutical  business  in  Germany.  The  acquisition
consisted of personnel (approximately 200 employees; 140 of  whom
are in the sales force) and product registrations and trademarks.
No  plant, property or manufacturing equipment were part  of  the
acquisition.

      The Company financed the $153,000 purchase price under  its
1999  Credit  Facility.  On  June 2,  1999,  the  Company  repaid
borrowings  under  the 1999 Credit Facility  with  a  substantial
portion  of the proceeds from the issuance of the 06 Notes.  Such
repayment created the capacity under the 1999 Credit Facility  to
incur the borrowings used to finance the acquisition of Isis.

      The  preliminary  fair  value of the  assets  acquired  and
liabilities  assumed  and  the results  of  Isis  operations  are
included  in  the  Company's  consolidated  financial  statements
beginning  on  June  15,  1999. The  Company  is  amortizing  the
acquired  intangibles and goodwill based on preliminary estimates
of  lives  over  an average of approximately 16 years  using  the
straight line method.

I.D. Russell:

      On  September  2,  1999,  the Company's  AHD  acquired  the
business  of  I.D.  Russell  Company  Laboratories  ("IDR")   for
approximately $22,000 in cash. IDR is a US manufacturer of animal
health  products primarily soluble antibiotics and vitamins.  The
acquisition  consisted  of  working  capital,  an  FDA   approved
manufacturing   facility  in  Colorado,  product   registrations,
trademarks and 35 employees.

      The  preliminary  fair  value of  the  assets  acquired  is
included  in  the  Company's  consolidated  financial  statements
beginning on the acquisition date. The Company will allocate  the
purchase  price  to  the  manufacturing facility  and  identified
intangibles.   The  balance  of  the  purchase  price  has   been
allocated  to intangible assets and goodwill which will generally
be amortized over 15 years.

Southern Cross:

      On  September  23,  1999, the Company's  AHD  acquired  the
business of Southern Cross Biotech, Pty. Ltd. ("Southern  Cross")
and   the   exclusive   worldwide  license   for   REPORCIN   for
approximately  $14,000 in cash. Southern Cross is  an  Australian
manufacturer  and  marketer of REPROCIN. REPROCIN  is  a  product
which  is  used  to  aid in the production of leaner  swine.  The
purchase  price  included the rights to the  countries  in  which
REPORCIN has already received regulatory approval and the  assets
of  Southern  Cross.  Under the terms of  the  license  agreement
additional cash payments will be made as regulatory approvals are
obtained   and   licenses  granted  in  other  countries.   Total
additional  payments will approximate $65,000 if all 13  possible
country approvals are received over the next 4-6 years.

      The  preliminary  fair  value of the  assets  acquired  and
liabilities assumed and the results of Southern Cross' operations
are  included in the Company's consolidated financial  statements
beginning on the acquisition date. The Company is amortizing  the
acquired  intangibles and goodwill based on preliminary estimates
of lives generally over an average of 15 years using the straight
line method.

Proforma Information:

     The following pro forma information on results of operations
assumes  the  purchase  of all significant  businesses  discussed
above  as if the companies had combined at the beginning of  each
period presented:

                             Proforma            Proforma
                        Three Months Ended   Nine Months Ended
                           September 30,       September 30,
                          1999      1998      1999      1998*

Revenue                 $206,300  $189,700  $571,600  $543,300
Net income              $11,600    $7,300   $26,700   $18,100
Basic EPS                $0.42      $0.29     $0.97     $0.71
Diluted EPS              $0.39      $0.28     $0.93     $0.70

*   Excludes   actual  non-recurring  charges  related   to   the
acquisition of Cox of $3,130 after tax or $0.12 per share.

      These  unaudited pro forma results have been  prepared  for
comparative  purposes only and include certain adjustments,  such
as  additional  amortization expense  as  a  result  of  acquired
intangibles  and  goodwill and an increased interest  expense  on
acquisition  debt.  They do not purport to be indicative  of  the
results  of operations that actually would have resulted had  the
acquisitions occurred at the beginning of each respective period,
or of future results of operations of the consolidated entities.

5.   Earnings Per Share

      Basic earnings per share is based upon the weighted average
number  of common shares outstanding. Diluted earnings per  share
reflect  the  dilutive  effect  of stock  options,  warrants  and
convertible debt when appropriate.

      A reconciliation of weighted average shares outstanding for
basic  to  diluted  weighted average  shares  outstanding  is  as
follows:

(Shares in thousands)   Three Months Ended   Nine Months Ended
                          Sept.     Sept.     Sept.     Sept.
                           30,       30,       30,       30,
                          1999      1998      1999      1998

Average shares
outstanding - basic     27,555     25,437    27,439    25,391
Stock options              392        244       375       194
Warrants                   --         552        --       359
Convertible notes       12,039      6,744     6,744       -
Average shares
outstanding - diluted   39,986     32,977    34,558    25,944

     The amount of dilution attributable to the stock options and
warrants determined by the treasury stock method depends  on  the
average  market  price  of the Company's common  stock  for  each
period.

      Subordinated  notes issued in March 1998, convertible  into
6,744,481  shares  of  common stock at  $28.59  per  share,  were
included  in the computation of diluted EPS for the three  months
ended  September 30, 1999 and 1998 and for the nine months  ended
September 30, 1999. The calculation of the assumed conversion was
antidilutive for the nine months ended September 30, 1998.

       In  addition,  the  06  Notes  issued  in  June  1999  and
convertible into 5,294,301 shares of common stock at  $32.11  per
share,  were included in the computation of diluted EPS  for  the
three  months  ended September 30, 1999. The calculation  of  the
assumed  conversion was antidilutive for the  nine  months  ended
September 30, 1999.

     The numerator for the calculation of basic EPS is net income
for all periods. The numerator for the calculation of diluted EPS
is  net income for the nine months ended September 30, 1998.  The
numerator  for all other periods presented includes an  add  back
for  interest expense and debt cost amortization, net  of  income
tax effects, related to the convertible notes.

     A reconciliation of net income used for basic to diluted EPS
is as follows:

                            Three Months Ended   Nine Months Ended
                              Sept.     Sept.     Sept.     Sept.
                               30,       30,       30,       30,
                              1999      1998      1999      1998

Net income - basic          $11,263   $7,551    $26,471   $15,258
Adjustments under the if-
converted method, net of     3,839     1,812     5,565       -
tax
Adjusted net income -       $15,102   $9,363    $32,036   $15,258
diluted


6.   Supplemental Data

                              Three Months        Nine Months
                                  Ended              Ended
                              Sept     Sept      Sept     Sept
                              30,       30,      30,      30,
                              1999     1998      1999     1998
Other income (expense),
net:
 Interest income              $260     $322     $704    $  590
 Foreign exchange losses,    (622)    (567)    (890)    (1,055)
net
 Amortization of debt costs  (498)    (798)    (1,155)  (1,091)
 Litigation settlement          -       670    1,000      670
 Income from joint venture
       carried at equity       286       -       934       -
 Gain (loss) on sale of
assets, net                   (38)     (62)     (94)      619
 Other, net                   (61)       58     (251)      72
                            $(673)    $(377)   $  248   $(195)




                               Nine Months
                                  Ended
                              Sept     Sept
                              30,       30,
                              1999     1998
Supplemental cash flow
information:

Cash paid for interest (net
of                          $19,986   $14,310
 amount capitalized)
Cash paid for income taxes
 (net of refunds)            $9,018   $3,640

Detail of businesses
acquired:
 Fair value of assets       $252,810  $230,740

 Liabilities                  43,482    33,229

 Cash paid                  209,328    197,511

 Less cash acquired           5,920       467
 Net cash paid for
  acquisitions              $203,408  $197,044



7.   Reporting Comprehensive Income

      As  of  January 1, 1998, the Company adopted  Statement  of
Financial  Accounting  Standards No. 130 (SFAS  130),  "Reporting
Comprehensive   Income."  SFAS  130  requires  foreign   currency
translation  adjustments to be included  in  other  comprehensive
income   (loss).   Total   comprehensive   income   amounted   to
approximately  $27,332  and $19,548 for the  three  months  ended
September  30,  1999 and 1998, respectively. Total  comprehensive
income amounted to approximately $18,961 and $21,340 for the nine
months ended September 30, 1999 and 1998. The only components  of
accumulated other comprehensive income (loss) for the Company are
foreign currency translation adjustments.

8.   Contingent Liabilities and Litigation

      The  Company is one of multiple defendants in  28  lawsuits
(after the dismissal in the second and third quarters of 1999  of
47  lawsuits) alleging personal injuries and seven class  actions
for  medical  monitoring resulting from the  use  of  phentermine
distributed by the Company and subsequently prescribed for use in
combination  with  fenflurameine or dexfenfluramine  manufactured
and  sold  by other defendants (Fen-Phen Lawsuits). None  of  the
plaintiffs  have specified an amount of monetary damage.  Because
the   Company   has   not  manufactured,  but  only   distributed
phentermine, it has demanded defense and indemnification from the
manufacturers  and  the insurance carriers of manufacturers  from
whom it has purchased the phentermine. The Company has received a
partial  reimbursement  of  litigation  costs  from  one  of  the
manufacturer's   carriers.  Based  on  an   evaluation   of   the
circumstances as now known, including but not solely limited  to:
1)  the fact that the Company did not manufacture phentermine, 2)
it  had  a diminimus share of the phentermine market and  3)  the
presumption  of  some insurance coverage, the  Company  does  not
expect  that  the  ultimate resolution of  the  current  Fen-Phen
lawsuits will have a material impact on the financial position or
results of operations of the Company.

     Bacitracin zinc, one of the Company's feed additive products
has  been  banned  from  sale in the European  Union  (the  "EU")
effective  July  1,  1999.  The Company's  request  for  a  court
injunction to prevent the imposition of the ban was rejected. The
Company is continuing to actively pursue other initiatives, based
on  scientific evidence available for the product, to  limit  the
effects  of this ban although an assurance of success  cannot  be
given.  In  addition,  certain  other  countries,  not  presently
material  to  the Company's sales of bacitracin zinc have  either
followed  the  EU's  ban  or  are considering  such  action.  The
existing  governmental actions negatively  impact  the  Company's
business but are not material to the Company's financial position
or  results  of operations. However, an expansion of the  ban  to
further  countries  where  the  Company  has  material  sales  of
bacitracin  based  products could be material  to  the  financial
condition and results of operations of the Company. (Also see
Management's Discussion and Analysis - Risk Factors).

      The  Company and its subsidiaries are, from time  to  time,
involved  in other litigation arising out of the ordinary  course
of  business.  It  is the view of management, after  consultation
with  counsel, that the ultimate resolution of all other  pending
suits   should  not  have  a  material  adverse  effect  on   the
consolidated financial position or results of operations  of  the
Company.

9.   Business Segment Information

      The  Company's  reportable segments are five  decentralized
divisions  (i.e. International Pharmaceuticals Division  ("IPD"),
Fine  Chemicals  Division ("FCD"), U.S. Pharmaceuticals  Division
("USPD"),  Animal  Health  Division ("AHD")  and  Aquatic  Animal
Health  Division  ("AAHD"). Each division  has  a  president  and
operates  in  distinct business and/or geographic  area.  Segment
data   includes  immaterial  intersegment  revenues   which   are
eliminated in the consolidated accounts.

      The  operations  of  each segment are  evaluated  based  on
earnings before interest and taxes and return on capital employed
("ROCE"). Corporate expenses and certain other expenses or income
not directly attributable to the segments are not allocated.

                         Three Months Ended September 30,
                     1999        1998         1999       1998
                          Revenues                 Income

IPD               $84,057      $52,254     $11,716    $2,687
USPD               59,421       52,085       7,555     5,449
FCD                15,331       12,005       5,773     3,795
AHD                40,664       41,787       9,542     9,496
AAHD                5,383        7,528       (211)     3,189
Unallocated and
 eliminations      (1,725)     (1,322)     (5,419)    (5,099)
                  $203,131    $164,337
Interest expense                           (11,257)   (7,454)
  Pretax income                            $17,699   $12,063


                            Nine Months Ended September 30,
                     1999        1998         1999       1998
                          Revenues                 Income

IPD               $212,257    $134,711     $24,738    $5,087
USPD              141,172      128,248      11,998     7,790
FCD                46,783       37,898      17,719    12,233
AHD               116,238      119,367      28,043    26,429
AAHD               10,017       13,539     (2,051)     2,877
Unallocated and
 eliminations      (2,738)     (3,351)     (11,181)   (9,971)
                  $523,729    $430,412
Interest expense                           (27,580)  (18,433)
  Pretax income                            $41,686  $ 26,012

      At December 31, 1998 IPD identifiable assets were $379,217.
Due primarily  to  the  acquisitions  of  Jumer  and  Isis  the
identifiable   assets   of  IPD  at  September   30,   1999   are
approximately $585,000.

10.  Strategic Alliances

Joint Venture:

      In  January  1999,  the  AHD contributed  the  distribution
business of its Wade Jones Company ("WJ") into a partnership with
G&M  Animal  Health  Distributors and T&H  Distributors.  The  WJ
distribution  business  which was  merged  had  annual  sales  of
approximately  $30,000 and assets (primarily accounts  receivable
and  inventory) of less than $10,000. The Company owns 50% of the
new  entity,  WYNCO LLC ("WYNCO"). The Company accounts  for  its
interest in WYNCO under the equity method.

      WYNCO  is a regional distributor of animal health  products
and  services primarily to integrated poultry and swine producers
and  independent dealers operating in the Central South West  and
Eastern  regions  of the U.S. WYNCO is the exclusive  distributor
for  the  Company's  animal  health products.  Manufacturing  and
premixing operations at WJ remain part of the Company.

Ascent Loan Agreement and Option:

      On  February  4,  1999, the Company  entered  into  a  loan
agreement with Ascent Pediatrics, Inc. ("Ascent") under which the
Company  may  provide  up to $40,000 in loans  to  Ascent  to  be
evidenced  by  7 1/2%  convertible  subordinated  notes  due   2005.
Pursuant to the loan agreement, up to $12,000 of the proceeds  of
the  loans  can  be  used  for general corporate  purposes,  with
$28,000  of  proceeds  reserved  for  projects  and  acquisitions
intended to enhance the growth of Ascent. All potential loans are
subject to Ascent  meeting a number of terms and conditions at the
time  of each  loan.  As of September 30, 1999, the Company  had
advanced $7,000 to Ascent under the agreement.

      In  addition, Ascent and the Company have entered  into  an
amended  agreement under which the Company will have  the  option
during  the  first  half  of 2003 to  acquire  all  of  the  then
outstanding shares of Ascent for cash at a price to be determined
by  a  formula based on Ascent's operating income during its 2002
fiscal year. The amended agreement which extended the option from
2002 to 2003 and altered the formula period from 2001 to 2002  is
subject to approval by Ascent's stockholders. (Also see Management's
Discussion and Analysis - Financial Condition).

11.  Management Actions

      In  July 1999, the Company made the decision to rationalize
Aquatic  Animal Health production capacity by closing or  selling
its Bellevue, Washington plant and severing all 21 employees. The
plant  is  expected  to  be  closed or  sold  and  all  employees
terminated by the end of 1999.

      In  July  the  Company informed all employees the  facility
would  be closed or sold and all employees would be severed.  The
severance terms were explained and approximately $575 was accrued
in  the  third quarter. As of September 30, 1999 the Company  was
considering  various  sales  options  in  lieu  of  closing   the
facility.  The fourth quarter of 1999 is expected  to  include  a
charge which will vary depending on whether the plant is sold  or
closed.  If the plant is closed the charge is presently estimated
to be between $1,500 and $2,500 pre-tax.

12.  Recent Accounting Pronouncements

      In  June  1998,  the Financial Accounting  Standards  Board
(FASB)  issued  Statement of Financial Accounting  Standards  No.
133,   "Accounting   for  Derivative  Instruments   and   Hedging
Activities"  (SFAS  133).  SFAS  133,  as  amended  in  1999,  is
effective  for all fiscal quarters of all fiscal years  beginning
after  June 15, 2000 (January 1, 2001 for the Company). SFAS  133
requires  that  all  derivative instruments be  recorded  on  the
balance  sheet at their fair value. Changes in the fair value  of
derivatives are recorded each period in current earnings or other
comprehensive  income,  depending  on  whether  a  derivative  is
designated as part of a hedge transaction and, if it is, the type
of hedge transaction.

      SFAS  133 is not expected to have a material impact on  the
Company's consolidated results of operations, financial  position
or cash flows.

Item 2.   Management's Discussion and Analysis of Financial
          Condition and Results of Operations

Overview

     Operations  in  the  first  nine  months  of  1999  improved
relative to the comparable period in 1998. During the 1999 period
a number of transactions occurred, including:

- - In  January, the Company contributed the distribution  business
  of  its  Wade  Jones subsidiary into a joint venture  with  two
  similar  third-party distribution businesses. The  new  entity,
  WYNCO,  which  is  a  regional  distributor  of  animal  health
  products in the Central South West and Eastern regions  of  the
  U.S., is 50% owned by Alpharma.

- - In  January, the Company replaced its revolving credit facility
  and  existing  domestic short term credit lines with  a  $300.0
  million   syndicated  facility  which  provides  for  increased
  borrowing capacity.

- -In   February,  USPD  entered  into  an  agreement  with  Ascent
 Pediatrics,  Inc.,  a branded pediatric pharmaceutical  company,
 under  which  USPD  may  provide up to $40.0  million  in  loans
 subject  to  Ascent  meeting agreed  terms  and  conditions.  In
 addition, the Company will have the option to acquire Ascent  in
 2003  for  a  price  based  on Ascent's  operating  income.  See
 "Financial Condition" below for additional information.

- -In   April,  the  Company's  IPD  purchased  a  French   generic
 pharmaceutical  business  for  approximately  $26.4  million  in
 cash.

- -  In  June,  the Company issued $170.0 million initial principal
 amount of 3% Convertible Senior Subordinated Notes due 2006.

- - In  June,  the Company's IPD acquired the Isis Pharma Group,  a
  German generic pharmaceutical business for approximately $153.0
  million in cash.

- - In  September  the Company's AHD acquired the business  of  the
  I.D.  Russell  Company, a privately held US-based  manufacturer
  of  animal health products, for approximately $22.0 million  in
  cash.

- - In  September,  the  Company's AHD  acquired  the  business  of
  Southern  Cross  Biotech, an Australian animal health  company,
  and  a  technology license for approximately $14.0  million  in
  cash.


Results of Operations - Nine Months Ended September 30, 1999

     Total  revenue increased $93.3 million (21.7%) in  the  nine
months  ended  September  30, 1999 compared  to  1998.  Operating
income  in 1999 was $69.0 million, an increase of $24.4  million,
compared  to 1998. Net income was $26.5 million ($.93  per  share
diluted)  compared to $15.3 million ($.59 per share  diluted)  in
1998.  Results  for 1998 include non-recurring charges  resulting
from the Cox acquisition which reduced net income by $3.1 million
($.12 per share).

     Revenues increased in the Human Pharmaceuticals business  by
$99.4  million  and were $6.7 million lower in the Animal  Health
business.  Currency translation of international sales into  U.S.
dollars  was not a major factor in the increases or decreases  of
any business segment.

     Changes  in revenue and major components of change for  each
division  in  the  nine  month period ended  September  30,  1999
compared to September 30, 1998 are as follows:

     Revenues in IPD increased by $77.5 million due primarily  to
the  acquisitions  in  1998  and 1999  ($62.7  million  aggregate
increase  due  mainly  to  the Cox and  Isis  acquisitions).  The
introduction  of  new  products and price  increases  which  were
offset  partially by lower volume in certain markets account  for
the  balance of the IPD increase.  Cox revenues grew in 1999 from
higher  volume and pricing due in large part to favorable  market
conditions  which  may  not  continue  in  2000.  USPD   revenues
increased  $12.9 million due to volume increases in existing  and
new   products  and  revenue  from  licensing  activities  offset
partially by lower net pricing. Revenues in FCD increased by $8.9
million  due mainly to volume increases in vancomycin, bacitracin
and  amphotericin.  AHD revenues decreased $3.1  million  due  to
increased  volume  in the poultry and cattle markets  being  more
than  offset  by sales previously recorded by Wade Jones  company
now   being  recorded  by  WYNCO,  the  Company's  joint  venture
distribution company. (i.e. WYNCO joint venture revenues are  not
included in the Company's consolidated sales effective in January
1999  when  the  joint venture commenced.) AAHD sales  were  $3.5
million  lower due to increased competition and an  inability  to
supply certain products from the Bellevue, Washington facility.

     On  a  consolidated  basis,  gross  profit  increased  $57.2
million  and the gross margin percent increased to 45.2% in  1999
compared to 41.7% in 1998. Gross profit in 1998 was reduced by  a
$1.3 million charge related to the acquisition of Cox (or .3%).

     A  major  portion  of the dollar increase in  the  Company's
consolidated  gross profits was recorded in IPD and results  from
the 1998 and 1999 acquisitions (particularly Cox and Isis). Other
increases  are attributable to higher volume, manufacturing  cost
reductions and yield efficiencies in AHD and FCD and sales of new
products  and  licensing activities in IPD  and  USPD.  Partially
offsetting  increases  were  volume  decreases  in  certain   IPD
markets,  lower  vaccine  sales by AAHD  and  lower  net  pricing
primarily in USPD.

     Operating  expenses increased $32.8 million and  represented
32.0%  of  revenues in 1999 compared to 31.3% in  1998.  A  major
portion  of  the increase is attributable to the  1998  and  1999
acquisitions which include operating expenses and amortization of
intangible assets acquired. Other increases included professional
and consulting fees for litigation and administrative actions  to
attempt  to  reverse the European Union ban on  bacitracin  zinc,
consulting  expenses for information technology and acquisitions,
severance expenses and annual increases in compensation including
incentive  programs. Operating expenses in 1998 include  a  write
off  of  in-process research and development of $2.1 million  and
$.2 million for severance related to the Cox acquisition.

     Operating  income  increased  $24.4  million  (54.6%).   IPD
accounted for $19.7 million of the increase primarily due to 1998
and  1999  acquisitions (especially Cox due to  favorable  market
developments), the absence of 1998 acquisition charges related to
Cox,  price increases and new product sales. Increased  operating
income was recorded by AHD due primarily to increased volume,  by
USPD due to higher volume and licensing activities net of pricing
reductions,  and  by  FCD  due  to  increased  volume  mainly  in
vancomycin,  bacitracin and amphotericin.  Increases  in  certain
operating   expenses  and  lower  AAHD  income  offset  increased
operating income to some extent.

     Interest  expense  increased in 1999  by  $9.1  million  due
primarily  to debt incurred to finance the acquisitions  of  Cox,
Isis and other 1998 and 1999 acquisitions.

     Other,  net was $.2 million income in 1999 compared  to  $.2
million  expense  in  1998. Other, net in  1999  includes  patent
litigation  settlement income of $1.0 million and  equity  income
from  the WYNCO joint venture of $.9 million. 1998 included gains
on  property sales of $.7 million and a litigation settlement  of
$.7 million.

Results of Operations - Three Months Ended September 30, 1999

     Total  revenue increased $38.8 million (23.6%) in the  three
months  ended  September  30, 1999 compared  to  1998.  Operating
income  in  1999 was $29.6 million, an increase of $9.7  million,
compared  to 1998. Net income was $11.3 million ($.38  per  share
diluted)  compared  to $7.6 million ($.28 per share  diluted)  in
1998.

     Revenues increased in the Human Pharmaceuticals business  by
$42.5  million and declined by $3.3 million in the Animal  Health
business.  Currency translation of international sales into  U.S.
dollars  was not a major factor in the increases or decreases  of
any business segment.

     Changes  in revenue and major components of change for  each
division  in  the  three month period ended  September  30,  1999
compared to September 30, 1998 are as follows:

     Revenues in IPD increased by $31.8 million due primarily  to
the  acquisitions in 1999 ($21.9 million primarily due to  Isis),
the  introduction of new products and selected price  and  volume
increases for Cox as a result of favorable market conditions that
may  not  continue in 2000. USPD revenues increased $7.3  million
due  to volume increases in existing and new products and revenue
from  licensing activities offset partially by lower net pricing.
Revenues  in FCD increased by $3.3 million due mainly  to  volume
increases  in vancomycin, bacitracin and polymyxin. AHD  revenues
decreased $1.1 million due to sales previously recorded  by  Wade
Jones  company  now being recorded by Wynco, the company's  joint
venture  distribution company. (i.e. Wynco joint venture revenues
are not included in the Company's consolidated sales effective in
January  1999 when the joint venture commenced.) AHD revenues  in
core  product lines increased in volume and sales of I.D. Russell
acquired in September 1999 partially offset the reduction due  to
the  establishment  of the joint venture. AAHD  sales  were  $2.1
million  lower due to increased competition and an inabililty  to
supply certain products from the Bellevue, Washington facility.

     On  a  consolidated  basis,  gross  profit  increased  $27.6
million  and the gross margin percent increased to 46.4% in  1999
compared to 40.6% in 1998.

     A  major portion of the increase in dollars was recorded  by
IPD   and   is  mainly  attributable  to  the  1999  acquisitions
(primarily  Isis) and selected price increases.  Other  increases
are  attributable to higher volume, manufacturing cost reductions
and  yield  efficiencies in USPD, AHD and FCD and  sales  of  new
products  and licensing activities in USPD. Partially  offsetting
increases were volume decreases in certain IPD markets and  lower
net pricing primarily in USPD.

     Operating  expenses increased $17.9 million and  represented
31.8% of revenues in 1999 compared to 28.5% in 1998. The increase
results   mainly   from  operating  expenses  related   to   1999
acquisitions   including  amortization  of   intangible   assets,
increased selling and marketing expenses related to higher sales,
severance expenses and increased consulting expenses.

     Operating   income  increased  $9.7  million  (48.9%).   IPD
operating income increased $9.0 million due to increased  pricing
mainly at Cox, new product sales and 1999 acquisitions. Increases
were  recorded by AHD due primarily to increased volume, by  USPD
due  to  volume increases exceeding lower net pricing and by  FCD
due  to  increased volume. AAHD operating income declined due  to
decreased revenues and charges recorded for severance  at  the
Bellevue, Washington facility which will be closed or sold.

     Interest  expense  increased in 1999  by  $3.8  million  due
primarily to debt incurred to finance the acquisition of Isis and
other  1999  acquisitions and to a lesser extent higher  interest
rates in 1999.

Taxes

     The  effective tax rate for the three and nine months  ended
September  30,  1999 was 36.4% and 36.5% compared  to  37.4%  and
41.3%  in the comparable periods in 1998. The primary reason  for
the   higher  rate  in  1998  was  the  charges  related  to  the
acquisition of Cox included a $2.1 million expense for in-process
research and development which is not tax benefited.

Management Actions

     The dynamic nature of our business gives rise, from time  to
time,   to  additional  opportunities  to  rationalize  personnel
functions    and   operations   to   increase   efficiency    and
profitability.   Management  is  continuously   reviewing   these
opportunities and may take actions in the future which  could  be
material  to  the results of operations in the quarter  they  are
announced.

     In  this regard, the AAHD in July 1999 concluded a study  of
production  capacity  and recommended that  the  AAHD's  Bellevue
Washington  facility be closed or sold by the end  of  1999.  The
proposal  was  approved by executive management and  21  affected
employees were informed in July 1999. The action required charges
in the third quarter of 1999 for severance of $.6 million.

     As of September 30, 1999 the Company was considering various
sale  options in lieu of closing the facility. The fourth quarter
of 1999 is expected to include a charge which will vary depending
on  whether the plant is sold or closed. If the plant  is  closed
the  charge is presently estimated to be between $1.5 million and
$2.5 million pre-tax.

      It  is  expected that most of the products produced at  the
Bellevue facility will be produced in future years at the  AAHD's
Overhalla facility.

Year 2000

General

  The  Company  began  its program to address its  potential  Y2K
issues  in late 1996 and has organized its activities to  prepare
for  Y2K at the division level. The divisions have focused  their
efforts  on  three  areas: (1) information systems  software  and
hardware;  (2)  manufacturing facilities and  related  equipment;
(i.e.  embedded  technology)  and (3)  third-party  relationships
(i.e.  customers, suppliers, and other). Information  system  and
hardware  Y2K  efforts are being coordinated by  an  IT  steering
committee composed of divisional personnel.

  The  Company and the divisions have organized their  activities
and  are  monitoring their progress in each area by the following
four phases:

Phase 1:  Awareness/Assessment   -   identify,    quantify    and
          prioritize business and financial risks by area.

Phase 2:  Budget/Plan/Timetable - prepare a plan including  costs
          and target dates to address phase 1 exposures.

Phase 3:  Implementation - execute the plan prepared in phase 2.

Phase 4:  Testing/Validation - test and validate the  implemented
          plans to insure the Y2K exposure has been eliminated or
          mitigated.

State of Readiness

  The  Company  summarizes its divisions' state of  readiness  at
September 30, 1999 as follows:

Information Systems and Hardware

                                         Quarter forecasted
                    Approximate range    for substantial
Phase               of completion        completion

1                   100%                 Completed
2                   100%                 Completed
3                   95 - 100%            4th Quarter 1999
4                   95 - 100%            4th Quarter 1999



Embedded Factory Systems


                    Approximate range    Quarter forecasted
Phase               of completion        for substantial
                                         completion
1                   100%                 Completed
2                   100%                 Completed
3                   95 -100%             4th Quarter 1999
4                   95 -100%             4th Quarter 1999


Third Party Relationships


                    Approximate range   Quarter forecasted
Phase               of completion       for substantial
                                        completion
1                   100% (a)            Completed (a)
2                   100% (a)            Completed (a)
3                   95 - 100% (a)(b)    4th Quarter 1999(a,b)
4                   90 - 100% (a)(b)    4th Quarter 1999(a,b)


(a)  Refers  to  significant identified risks - (e.g.  customers,
     suppliers  of raw materials and providers of services)  does
     not include exposures that relate to interruption of utility
     or government provided services.

(b)  Awaiting  completion of vendor response  and  follow-up  due
     diligence to Y2K readiness surveys.

Cost

     The  Company expects the costs directly associated with  its
Y2K efforts to be between $2.25 million and $2.5 million of which
approximately  $2.0  million has been spent  to  date.  The  cost
estimates do not include additional costs that may be incurred as
a  result of the failure of third parties to become Y2K compliant
or costs to implement any contingency plans.

Risks

    The   Company   had  previously  identified   the   following
significant reasonably possible Y2K problems:

  - Possible problem: the inability of significant sole source
    suppliers of raw materials or active ingredients to provide
    an uninterrupted supply of material necessary for the
    manufacture of Company products.

  - Possible problem: the failure to properly interface caused by
    noncompliance of significant customer operated electronic
    ordering systems.

  - Possible problem: the shutdown or malfunctioning of Company
    manufacturing equipment.

    Since these possible problems were initially identified, risk
remediation progress has, in the opinion of the Company,  reduced
the likelihood of these Y2K risks:

  - Sole  source  suppliers: substantially all major sole  source
    suppliers  were certified by Company inspection or have  self
    certified as Y2K compliant as of September 30, 1999.

  - E-Commerce  risk:  the Company has been advised  by  a  third
    party  engaged  to review this area that it is Y2K  compliant
    with respect to E-Commerce as of September 30, 1999.

  - Shutdown  of  manufacturing  equipment:  plants  were  tested
    during  vacation  shutdowns and no significant  Y2K  problems
    were identified as a result of the testing.

    Based  on  the  assessment and remediation efforts  to  date,
which  are  substantially complete, the Company does not  believe
that  the  Y2K issue will have a material adverse effect  on  its
financial condition or results of operation. The Company believes
that  any effect of the Year 2000 issue will be mitigated because
of the Company's divisional operating structure, which is diverse
both  geographically  and with respect to customer  and  supplier
relationships.  Therefore, the adverse effect of most  individual
failures should be isolated to an individual product, customer or
Company  facility.  However, there can be no assurance  that  the
systems  of  third parties on which the Company  relies  will  be
converted  in  a  timely manner, or that a  failure  to  properly
convert  by  another  company would not have a  material  adverse
effect on the Company.

    The  Company's  Y2K program is an ongoing  process  that  may
uncover  additional  exposures and all  estimates  of  costs  and
completion are subject to change as the process continues.

Risk Factors

     The Company is updating the Governmental regulation risk
factor included in the 1998 Form 10-K as follows:

     The European Union and five non-EU countries have banned the
use  of  bacitracin zinc, a feed antibiotic growth  promoter,  in
livestock feeds effective July 1, 1999. The EU ban is based  upon
the "precautionary Principle" which states that a product may  be
withdrawn  from  the market based upon a finding of  a  potential
threat of serious or irreversible damage even if such finding  is
not   supported  by  scientific  certainty.  1998  sales  of  the
Company's  bacitracin  based products  were  approximately  $10.9
million in the EU and $1.8 million in the non-EU countries  which
have  also banned the product. The initial effort to reverse this
action  by  means of a court injunction from the Court  of  First
Instance  of  the  European  Court was  denied.  The  Company  is
continuing  its  attempts to reverse or limit this  action,  with
particular emphasis on political means. The Company believes that
strong  scientific evidence exists to refute the EU position.  In
addition, other countries are considering a similar ban.  If  the
loss  of  bacitracin zinc sales is limited to the European  Union
and  those countries that have already taken similar action,  the
Company does not anticipate a material adverse effect. If  either
(a)  other  countries more important to our sales of  bacitracin-
based  products ban these products or (b) the European Union  (or
countries  or  customers  within the  EU)  acts  to  prevent  the
importation of meat products from countries that allow the use of
bacitracin-based  products,  the  Company  could  be   materially
affected. A ban in the United States would be materially  adverse
to  the  Company. The Company cannot predict whether the  present
bacitracin zinc ban will be expanded.

Financial Condition

     Working  capital  at September 30, 1999 was  $203.6  million
compared  to  $165.0 million at December 31,  1998.  The  current
ratio was 2.12 to 1 at September 30, 1999 compared to 1.97  to  1
at year end. Long-term debt to stockholders' equity was 2.17:1 at
September 30, 1999 compared to 1.61:1 at December 31, 1998.

     The  increases in accounts receivable and inventories as  of
September 30, 1999, were due primarily to higher sales during the
third  quarter  of  1999  as  well as working  capital  increases
related  to  acquisitions in 1999.  The change in  the  Company's
long-term  debt to equity ratio was primarily the result  of  the
issuance  of  $170.0  million  initial  principal  amount  of  3%
Convertible  Senior Subordinated Notes in the second  quarter  of
1999   to  reduce  revolving  credit  debt  and  thereby   create
sufficient financing capacity to purchase the Isis Pharma  Group,
a  German  generic  pharmaceutical  business,  for  approximately
$153.0  million. In addition long term debt was incurred  in  the
third quarter 1999 to acquire two animal health businesses.

  All  balance sheet captions decreased as of September 30,  1999
compared  to  December  1998 in U.S. Dollars  as  the  functional
currencies  of the Company's principal foreign subsidiaries,  the
Norwegian  Krone,  Danish  Krone and British  Pound,  depreciated
versus   the  U.S.  Dollar  in  the  nine  months  of   1999   by
approximately  2%,  9%  and 1%, respectively.  In  addition,  the
Company's  operations in Brazil were negatively affected  due  to
the  decline  of  its  currency versus  the  U.S.  Dollar.  These
decreases  in  balance sheet captions impact to some  degree  the
above  mentioned ratios. The approximate decrease due to currency
translation  of  selected captions was: accounts receivable  $3.1
million,  inventories $2.5 million, accounts payable and  accrued
expenses  $2.0  million,  and  total  stockholders'  equity  $7.5
million.  The  $7.5  million  decrease  in  stockholder's  equity
represents  other  comprehensive loss for the nine  months  ended
September 30, 1999 resulting from the strengthening of  the  U.S.
dollar.

     In  February  1999,  the  Company's  USPD  entered  into  an
agreement  with  Ascent Pediatrics, Inc. ("Ascent")  under  which
USPD  may  provide up to $40 million in loans  to  Ascent  to  be
evidenced by 7 1/2% convertible subordinated notes due  2005.  Up
to  $12.0  million of the proceeds of the loans can be used  only
for  general  corporate purposes, with $28.0 million of  proceeds
reserved  for  approved  projects and  acquisitions  intended  to
enhance the growth of Ascent. All potential loans are subject  to
Ascent  meeting a number of terms and conditions at the  time  of
each loan. The exact timing and/or ultimate amount of loans to be
provided  cannot  be  predicted. As of  October  25,  1999,  $8.5
million has been advanced and additional amounts are expected  to
be requested.

     Ascent has incurred operating losses since its inception. An
important   element   of  Ascent's  business  plan   contemplated
commercial introduction of two pediatric pharmaceutical  products
which  require FDA approval. Ascent has received FDA approval  in
October  1999 of one product and the other product is subject  to
FDA  action  which  Ascent  believes will  delay  its  commercial
introduction   into  2000.  This  anticipated   delay   in   drug
introduction resulted in Ascent forecasting that its  accumulated
losses  would exceed the combined sum of its stockholders' equity
and  indebtedness subordinate to the Company's loans  during  the
first half of 2000. In response to this forecast, the Company and
Ascent  have  negotiated  amendments to the  original  agreements
providing  for  (a) a change in the option period (from  2002  to
2003),  (b)  a  change in the formula period for determining  the
price of the Company's purchase option from 2001 to 2002, (c) the
granting  of  a security interest to the Company in  products  or
business  purchased by Ascent with funds loaned by  Alpharma  and
(d) the commitment of a major shareholder of Ascent to provide up
to  $10.0  million of additional financing to Ascent (in addition
to   the  $4  million  previously  committed)subordinate  to  the
Company's  loan. The Company is required to recognize losses,  up
to  the amount of its loans, to the extent Ascent has accumulated
losses in excess of its stockholders' equity and the indebtedness
subordinate  to  the  Company's loans.  The  Company  is  further
required  to  assess the general collectability of its  loans  to
Ascent   and   make  any  appropriate  reserves.  The  additional
financing   results  in  Ascent  continuing  to   have   positive
stockholders'  equity  and  subordinated  indebtedness   assuming
current operating forecasts are met.

     In September 1999, the Company acquired a technology license
and  option  agreement  for  the  Southern  Cross  animal  health
product. The agreement requires additional payments as additional
regulatory  approvals  for  the product  are  obtained  in  other
markets. Total additional payments of approximately $65.0 million
are  required over the next 4-6 years (approximately $30  million
of  which  is expected over the next 2 years) if all 13  possible
country approvals are received.

     At September 30, 1999, the Company had $23.3 million in cash
and approximately $72.0 million available under existing lines of
credit.  In  January 1999, the Company replaced its prior  $180.0
million  revolving credit facility and domestic short term  lines
of  credit  with a $300.0 million credit facility.  In  addition,
European  short term credit lines were set at $30.0 million.  The
credit facility provides for a $100.0 million six-year term  loan
and  a  $200.0 million revolving credit facility with an  initial
five-year term with two possible one-year extensions. The  credit
facility  has several financial covenants, including an  interest
coverage  ratio, total debt to EBITDA ratio, and equity to  total
asset  ratio.  Interest on borrowings under the  facility  is  at
LIBOR plus a margin of between .875% and 1.6625% depending on the
ratio  of  total  debt to EBITDA. The Company believes  that  the
combination  of  cash from operations and funds  available  under
existing  lines  of  credit  will  be  sufficient  to  cover  its
currently planned operating needs and firm commitments in 1999.

     While   no  commitments  exist,  the  Company  is  presently
considering  and expects to continue its pursuit of complementary
acquisitions  or  alliances, both in  human  pharmaceuticals  and
animal   health,  that  can  provide  new  products  and   market
opportunities as well as leverage existing assets.  In  order  to
accomplish   any   individually   significant   acquisition    or
combination  of  acquisitions, the Company will  need  to  obtain
additional  financing  in the form of equity  related  securities
and/or  borrowings. Depending on the financing vehicle chosen  by
the  Company, it may require a restructuring or expansion of  the
1999 Credit Facility.

     The  Company is required to meet the debt covenants included
in  the  1999 Credit Facility. At September 30, 1999, the Company
had a equity to total asset ratio of 25.5% which is in excess  of
the  required 25%. The slight margin by which the Company met the
ratio  and  the possibility of not meeting the ratio  due  to  an
increase in assets or due to factors beyond the Company's control
such   as   currency  movements  has  resulted  in  the   Company
considering  certain  measures  which  could  include  an  equity
offering.


Item 3.   Quantitative and Qualitative Disclosures about Market
          Risk

      The  Company's  earnings  and  cash  flow  are  subject  to
fluctuations  due to changes in foreign currency  exchange  rates
and  interest  rates.  The  Company's  risk  management  practice
includes  the  selective  use, on a  limited  basis,  of  forward
foreign currency exchange contracts and interest rate agreements.
Such instruments are used for purposes other than trading.

     Foreign currency exchange rate movements create fluctuations
in the U.S. dollar reported amounts of foreign subsidiaries whose
local currencies are their respective functional currencies.  The
Company  has not used foreign currency derivative instruments  to
manage  translation fluctuations. The Company and its  respective
subsidiaries primarily use forward foreign exchange contracts  to
hedge certain cash flows denominated in currencies other than the
subsidiary's  functional currency. Such cash flows  are  normally
represented  by  actual receivables and payables and  anticipated
receivables and payables for which there is a firm commitment.

      At  September  30,  1999 the Company  had  forward  foreign
exchange  contracts with a notional amount of $10.7 million.  The
fair  market value of such contracts is essentially the  same  as
the notional amount. All contracts expire by the third quarter of
2000.  The  cash flows expected from the contracts will generally
offset   the  cash  flows  of  related  non-functional   currency
transactions. The change in value of the foreign currency forward
contracts  resulting  from  a 10% movement  in  foreign  currency
exchange  rates would be approximately $.6 million and  generally
would  be  offset by the change in value of the hedged receivable
or payable.

      At  September  30, 1999 the Company has  no  interest  rate
agreements outstanding. The Company is considering entering  into
interest  rate  agreements in 1999 and 2000 to fix  the  interest
rate on a portion of its long term debt.

____________

Statements  made in this Form 10Q, are forward-looking statements
made  pursuant  to the safe harbor provisions of  the  Securities
Litigation  Reform Act of 1995. Such statements  involve  certain
risks and uncertainties that could cause actual results to differ
materially   from  those  in  the  forward  looking   statements.
Information   on   other   significant   potential   risks    and
uncertainties not discussed herein may be found in the  Company's
filings with the Securities and Exchange Commission including its
Form 10-K for the year ended December 31, 1998.


Part II.  OTHER INFORMATION

Item 1.   Legal proceedings

      The  following  is an update of Environmental  Matters  and
Legal Proceedings included in Item 1 and 3 in the Company's  1998
Form 10-K:

     (a)  The  court has granted the Company's Motion for Summary
          Judgement with respect to the Drinking Water Act proceeding
          brought by the State of California. This ruling is final and
          binding as the State has not filed an appeal in the time
          permitted under applicable law. No monetary or other penalties
          were awarded against the Company in this matter.

     (b)  The  United States Environmental Protection Agency  has
          offered, and the Company has accepted, a tentative settlement
          with respect to the Superfund matter. Pursuant to this settlement
          (which must be approved by the court and is subject to a
          "reopener" relating to unanticipated site conditions as is
          normally contained in settlements under Superfund) the Company's
          liability would be nominal.

Item 5.   Other Information

      The Board of Directors accepted the resignation of Mr. Gert
W.  Munthe,  President and Chief Executive Officer  in  September
1999. Mr. Munthe's resignation will be effective on December  31,
1999 or earlier.

Item 6.   EXHIBITS AND REPORTS ON FORM 8-K

(a)  Exhibits.

     10.1 Resignation Agreement dated September 24, 1999 between the
          Company and Gert Munthe.

10.2 Second Supplemental Agreement dated October 15, 1999 by and
among Ascent Pediatrics Inc., Alpharma USPD Inc. and the Company.
     27   Financial Data Schedule.

(b)  Reports on Form 8-K.

     On August 30, 1999, the Company filed a report on Form 8-K/A
dated June 18, 1999 reporting Item 2. "Acquisition or Disposition
of Assets."

      The event reported was the acquisition of Isis. The Form 8-
K/A  included  the  audited  financial  statements  of  Isis  and
required pro forma financials.



                           SIGNATURES


Pursuant  to the requirements of the Securities Exchange  Act  of
1934, the registrant has duly caused this report to be signed  on
its behalf by the undersigned thereunto duly authorized.

                              Alpharma Inc.
                              (Registrant)









Date:      November 2, 1999        /s/ Jeffrey E. Smith
                              Jeffrey E. Smith
                              Vice President, Finance and
                              Chief Financial Officer



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<S>                             <C>
<PERIOD-TYPE>                   9-MOS
<FISCAL-YEAR-END>                          DEC-31-1999
<PERIOD-END>                               SEP-30-1999
<CASH>                                          23,305
<SECURITIES>                                         0
<RECEIVABLES>                                  192,921
<ALLOWANCES>                                         0
<INVENTORY>                                    155,958
<CURRENT-ASSETS>                               385,167
<PP&E>                                         420,278
<DEPRECIATION>                                 174,034
<TOTAL-ASSETS>                               1,171,741
<CURRENT-LIABILITIES>                          181,615
<BONDS>                                        365,009
                                0
                                          0
<COMMON>                                         5,573
<OTHER-SE>                                     292,836
<TOTAL-LIABILITY-AND-EQUITY>                 1,171,741
<SALES>                                        523,729
<TOTAL-REVENUES>                               523,729
<CGS>                                          287,233
<TOTAL-COSTS>                                  287,233
<OTHER-EXPENSES>                               167,478
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                              27,580
<INCOME-PRETAX>                                 41,686
<INCOME-TAX>                                    15,215
<INCOME-CONTINUING>                             26,471
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
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<NET-INCOME>                                    26,471
<EPS-BASIC>                                        .96
<EPS-DILUTED>                                      .93


</TABLE>

14












                   ASCENT PEDIATRICS, INC.




                SECOND SUPPLEMENTAL AGREEMENT


                   Date: October 15, 1999



           SECOND SUPPLEMENTAL AGREEMENT (the
"Agreement") dated as of October 15, 1999 among Ascent
Pediatrics, Inc., a Delaware corporation (the "Company"),
Alpharma USPD Inc., a Maryland corporation (the "Lender"),
Alpharma Inc., a Delaware corporation (the "Parent"),  State
Street Trust Bank and Trust Company (the "Depositary") and
each of the Original Lenders named in the Subordination
Agreement described below.

     WHEREAS, pursuant to the Loan Agreement dated as of
February 16, 1999 among the Company, the Lender and the
Parent (the "Loan Agreement"), the Lender has agreed to loan
to the Company an aggregate of up to $40 million from time
to time upon the terms and conditions set forth therein, as
amended as described below;

     WHEREAS, the Lender, the Company and the Depositary are
parties to a Depositary Agreement dated February 16, 1999,
as amended as described below (the "Depositary Agreement"):

     WHEREAS, the Lender, the Company and the Original
Lenders named therein are parties to a Subordination
Agreement dated February 16, 1999, as amended as described
below (the "Subordination Agreement"):

     WHEREAS, the Company, the Lender and the Parent are
parties to a Master Agreement dated February 16, 1999, as
amended as described below (the "Master Agreement");

     WHEREAS, the Loan Agreement, Depositary Agreement,
Subordination Agreement and the Master Agreement were
amended pursuant to the terms of the Supplemental Agreement
dated July 1, 1999 between the parties hereto (the
"Supplemental Agreement"):

     WHEREAS, the parties hereto wish to further supplement
and amend the Loan Agreement, the Depositary Agreement, the
Master Agreement, the Subordination Agreement and the
Supplemental Agreement upon the terms and conditions set
forth herein;

     WHEREAS, the Lender is the sole holder of the Note (as
defined in the Loan Agreement) and the parties are entering
into this Second Supplemental Agreement (to the extent it
modifies the Loan Agreement) pursuant to Section 12.1 of the
Loan Agreement;

     WHEREAS, on or prior to the date hereof, this Second
Supplemental Agreement has been approved by a majority of
the Non-Alpharma Directors pursuant to Section 9.01 of the
Depositary Agreement and Section 8.5 of the Master
Agreement;

     NOW,  THEREFORE, in consideration of the premises, it
is agreed by and among the parties hereto as follows:


                          ARTICLE I
                      DEFINITIONS, ETC.


1.1  Capitalized terms used herein and not otherwise defined
   herein shall have the meanings ascribed to them in the Loan
   Agreement or in the Ancillary Agreements (as defined in the
   Loan Agreement).


1.2  Unless the context otherwise requires:

     a.   a term has the meaning assigned to it;

     b.   an accounting term not otherwise defined has the
          meaning assigned to it in accordance with GAAP;

     c.   "or" is not exclusive;

     d.   words in the singular include the plural and in the
          plural include the singular;

     e.   provisions apply to successive events and transactions;
     and

     f.   "herein", "hereof" and other words of similar import
          refer to this Agreement as a whole and not to any particular
          Article, Section or other subdivision.

1.3     This Agreement amends and supplements the Loan
   Agreement, the Depositary Agreement, the Subordination
   Agreement, the Guaranty Agreement,  the Master Agreement
   and the Supplemental Agreement.  In case of any
   inconsistency between the terms of this Agreement and
   the Loan Agreement, the Depositary Agreement, the
   Subordination Agreement, the Guaranty Agreement,  the
   Master Agreement, or the Supplemental Agreement, the
   terms of this Agreement shall govern. In the absence of
   such inconsistency, all provisions of the Loan
   Agreement, the Depositary Agreement, the Subordination
   Agreement, the Guaranty Agreement,  the Master Agreement
   and the Supplemental Agreement shall remain in full
   force and effect.  Without limiting the foregoing, the
   conditions set forth in Article II hereof shall for all
   purposes be considered part of the Loan Agreement.  Any
   reference to the Loan Agreement, the Depositary
   Agreement, the Master Agreement, the Guaranty Agreement,
   the Subordination Agreement or the Supplemental
   Agreement in any such agreement or to the Ancillary
   Agreements shall be deemed to be a reference to such
   agreement as modified hereby.  Any reference in any such
   agreement to approval or adoption of the Merger
   Agreement and the transactions contemplated thereby
   shall be deemed to be a reference to the Merger
   Agreement and such transactions as modified hereby.


1.4   The parties may sign any number of copies of this
   Agreement.  Each signed copy shall be an original and
   may be signed in counterparts, but all of them together
   represent the same agreement.

1.5   The laws of the State of New York, without regard to
   principles of conflicts of law, shall govern this
   Agreement to the extent it modifies the Loan Agreement
   or the Subordination Agreement.  The laws of the State
   of Delaware, without regard to principals of conflict of
   laws, shall govern this Agreement to the extent it
   modifies the Depositary Agreement or the Master
   Agreement.


                              ARTICLE II
     ADDITIONAL CONDITIONS AND OBLIGATIONS OF THE LENDER

2.1  The obligation of the Lender to make any Loans on or
     after the date hereof is subject to the fulfillment to
     its reasonable satisfaction, or the waiver by the
     Lender, on or prior to the applicable Loan Date, of
     each of the following additional conditions:


     (a)  The Fourth Amendment to the May 1998 Securities
       Purchase Agreement in the form attached hereto as Exhibit A
       (the "Fourth Amendment to the Securities Purchase
       Agreement") shall be in full force and effect and

     (b) The Company and each of the Furman Selz Entities
       shall have performed in all material respects all of
       their respective obligations under the Fourth
       Amendment to the Securities Purchase Agreement
       including, without limitation, the satisfaction of
       the conditions set forth in Section 2.2(b) thereof.


2.2    The obligation of the Lender to make any Secured
   Loans (as defined in the Loan Agreement (as amended)) on
   or after the date hereof is subject to the fulfillment
   to its reasonable satisfaction, or the waiver by Lender,
   on or prior to the applicable Loan Date, of each of
   the following conditions:

             (a)  The Lender shall be reasonably satisfied
             that the
                security interest required by Section 13.10
                of the Loan
                Agreement (as amended) has attached to the
                Collateral (as defined in the Loan
                Agreement) and

             (b)  The Amendment to the Subordination
                Agreement, in the form attached hereto as
                Exhibit B shall be in full force and
                effect.



                                      ARTICLE III
                    AGREEMENTS AND AMENDMENTS

The Plan Update

3.1  The Lender agrees that the Company delivered to the
   Lender, on or about September 21, 1999, a detailed
   operating plan  covering the periods through December
   31, 2001 which includes, on an annual basis, $1.4
   million in research and development and sales force
   expenditure reductions from the previously approved Plan
   and reflects the immediate commercial introduction of
   the Primsol product. The representatives of the Company
   and the Lender agree to cause their respective
   representatives to the Screening Committee to take all
   action necessary to approve said September 21, 1999 plan
   as an Update, as that term is used in   Section 4.1 of
   the Supplemental Agreement.


The Secured Loan

3.2  The Loan Agreement (as amended) is further amended by
adding
   the following definitions to Section 1.1 thereof:

             "Secured Loans" means all Project Loans and
             Screened Project Loans.

             "Collateral" means all assets, properties,
             contract rights
             and other intangibles and choses in action
             purchased,
             licensed or otherwise acquired by the Company
             with the
             proceeds of a Secured Loan.


3.3 The Loan Agreement (as amended) is further amended by
   adding the following clause to Article XIII of the Loan
   Agreement:

        13.10 Security.

             As security for the full and timely payment of
             all Secured Loans and the performance of all
             obligations contained herein in connection
             with the Secured Loans, the Company covenants
             that it will, on or before each Loan Date for
             a Secured Loan, do or cause to be done, all
             things necessary in the reasonable opinion of
             the Lender and, its counsel, to grant to the
             Lender a duly perfected first priority
             purchase money security interest in all of the
             Collateral acquired by Company with the
             proceeds of said Secured Loan.  At the request
             of the Lender, the Company will cause its duly
             authorized officers to execute on its behalf,
             any certificate, instrument, statement or
             document, or to procure any such certificate,
             instrument, statement or document, or to take
             such other action which the Lender's counsel
             reasonably deems necessary, from time to time,
             to create, continue or preserve Lender's
             security interest in and to the Collateral
             (and the perfection and priority thereof) as
             contemplated hereby, specifically including
             the execution of such security agreement and
             the filing of such financing statements in the
             form reasonably requested by Lender's counsel.

   3.4   Section 7.2 of the Loan Agreement is hereby
          amended by adding the following clause to the
          beginning of the first sentence thereof:

              "Except for any security interest in the
              Collateral with respect to  Secured Loans and
              Fourth Amendment Advances (as defined in the
              Fourth Amendment to the Securities Purchase
              Agreement), ..."

     The Option Exercise Period

   3.5  The definition of the term "2001 Audited Financial
   Statements" in
       Article I of the Depositary Agreement (as amended by
       the Supplemental Agreement) is hereby amended by
       changing (a) the term "2001 Audited Financial
       Statements" to the term "2002 Audited Financial
       Statements" in said definition and in each other
       place where the term "2001 Audited Financial
       Statements" appears in the Depositary Agreement and
       (b) the date "December 31, 2001" to "December 31,
       2002" in each of the two places it appears in said
       definition.

   3.6  The definition of the term "Adjusted 2001 Operating
   Income" in
       Article I of the Depositary Agreement (as amended by
       the Supplemental Agreement) is hereby amended by
       changing (a) the term "Adjusted 2001 Operating
       Income" to the term "2002 Operating Income" in said
       definition and in each other place where the term
       "Adjusted 2001 Operating Income" appears in the
       Depositary Agreement and (b) the date "December 31,
       2001" to "December 31, 2002 in each of the five
       places it appears in said definition.

   3.7  The definition of the term "Excluded Interest
   Expense" in Article I of the
       Depositary Agreement (as amended by the Supplemental
       Agreement) is hereby amended by changing the date
       "December 31, 2001" each time it appears to
       "December 31, 2002.

   3.8  The definition of the term "GAAP Adjustments" in
       Article I of the Depositary Agreement (as amended by
       the Supplemental Agreement) is hereby amended by
       changing (a) all references to "2000" and "2001" to
       "2001" and "2002", respectively and (b) all
       references to "December 31, 2001" and "December 31,
       2002" to "December 31, 2002" and "December 31,
       2003", respectively.

   3.9  The definition of the term "Option Expiration Date"
       in Article I of the Depositary Agreement (as amended
       by the Supplemental Agreement) is hereby amended by
       changing the term "December 31, 2002" to "December
       31, 2003".

   3.10  Section 3.01 of the Depositary Agreement (as
   amended by the
        Supplemental Agreement) is hereby amended by (a)
        restating the last sentence of subsection (a) as
        follows:

             "The Company may elect to exercise the Call
             Option by
             delivery of the Call Option Exercise Notice to
             the
             Depositary at any time during the period (the
             "Call Period") commencing February 1, 2003 and
             continuing until December 31, 2003."

        and (b) changing the two references to "January 15,
   2003" in
        subsection (b) to "January 15, 2004".


   3.11 Section 4.01 of the Depositary Agreement (as
   amended by the
        Supplemental Agreement) is hereby amended by (a)
        restating the first sentence of subsection (a) as
        follows:

             "The Company shall deliver the Option Exercise
             Deliverables to Alpharma on or before March
             30, 2003."

        and (b) changing the reference to "January 1, 2002"
        in subsection (b) (v) to "January 1, 2003".


   3.12  Section 4.03 (c) (i) of the Depositary Agreement
(as amended by
        the Supplemental Agreement) is hereby amended by
        changing the reference to "September 30, 2001" to
        "September 30, 2002".


   3.13  Section 5.02 (b) of the Depositary Agreement (as
   amended by the
        Supplemental Agreement) is hereby amended by
        changing the reference in the second paragraph
        thereof from "January 15, 2003" to "January 15,
        2004".


   3.14.  Section 2.6 of the Loan Agreement (as amended) is
hereby
        amended by (a) changing the reference to "December
        31, 2002" to "December 31, 2003" and (b) changing
        the reference to "February 28, 2003" to "February
        28, 2004".

   3.15  Section 2.7 of the Loan Agreement (as amended) is
        hereby amended by changing the reference to
        "December 31, 2002" to "December 31,2003".

   3.16  Section 6.8 of the Loan Agreement (as amended) is
        hereby amended by changing the reference to the
        "2001 fiscal year" to the "2002 fiscal year".


   3.17  It is recognized that the stockholders of Ascent
   must approve
        the amendments contained in Sections 3.5 through
        3.16 of this
        Agreement (the "Option Extension Provisions") in
       order for such
        provisions to be effective.  The parties therefore
      agree that the
        Option Extension Provisions shall have no force and
        effect unless and until approved by the holders of
        a majority of the Depositary Shares (the "Favorable
        Shareholder Vote") and that, at all times prior to
        a Favorable Shareholder Vote, the Depositary
        Agreement shall continue to be in full force and
        effect in the form existing without considering the
        Option Extension Provisions.  A Favorable
        Shareholder Vote shall be deemed to have taken
        place (and the Option Extension Provisions shall
        thereupon be effective as amendments to the
        Depositary Agreement) upon the delivery to the
        Lender and the Depositary of an opinion of the
        Company's counsel to the effect that a Favorable
        Shareholder Vote has taken place and that each of
        the Agreements referred to in Section 1.3 of this
        Agreement (as amended hereby) are valid, binding
        and enforceable against the Company..  The failure
        to obtain a Favorable Shareholder Vote shall not
        effect any of the amendments or terms of this
        Agreement other than the Option Extension
        Provisions.


   The Minimum Purchase Price

   3.18 Subclause (i) of  Clause (A) of the
        definition of "Option Exercise Price" in Article I
        of the Depositary Agreement (as amended by the
        Supplemental Agreement) is amended and restated in
        its entirety as follows:

         "$140,000,000 plus an amount equal to all funds
          actually advanced to the Company under the Fourth
          Amendment to the Securities Purchase Agreement
          and which have not been repaid as of  the date of
          delivery of the Option Exercise Deliverables."

   Conditions for Unrestricted Loans

   3.19  The Lender agrees that the existence of a Plan or
   Update
        approved by the Screening Committee (as those terms
        are defined in the Supplemental Agreement) is not a
        condition precedent to the Lender's obligation to
        fund an Unrestricted Loan, and that Article III,
        Section (c) of the Supplemental Agreement is hereby
        amended and restated as follows:

             "The Lender shall be reasonably satisfied that
             the proceeds of any Project Loans or Screened
             Loans will be used for the purposes approved
             by the Screening Committee pursuant to Section
             4.3 of this Agreement."

   3.20  Section 4.1 of the Supplemental Agreement is
hereby amended by
        deleting the entire third sentence of such Section
which begins as
        follows:

               "Notwithstanding Section 6.6 of the Loan
               Agreement, the Company shall use the
               proceeds of Unrestricted Loans only for the
               purposes specified in the Plan..."

     General

   3.21 The definition of the term "Option Expiration Date"
       in the Depositary Agreement (as amended by the
       Supplemental Agreement) is amended by adding the
       following text to the end of such definition:

          "or Article II of the Second Supplemental
          Agreement dated October 13, 1999 between the same
          parties".

   3.22 Subclause III of Clause Y of the provision in the
       definition of the term "Option Exercise Price" in
       the Depositary Agreement (as amended by the
       Supplemental Agreement) is amended and restated in
       its entirety as follows:

          "(III) the 7.5% Convertible Subordinated Notes due
          July 1, 2004, in each case outstanding as of the
          Option Closing Date, or issued or issuable upon
          exercise of the warrants issued pursuant to the
          Series G Agreement, as amended by the fourth
          amendment hereto, dated as of October 1, 1999 (to
          the extent any shares continue to be held as of
          the Option Closing Date by one of the purchasers
          set forth on Schedule 1  to the Series G Agreement
          as so amended or an Affiliate of any such
          purchaser), the Original Option Exercise Price,
          and"

   3.23  Section 7.1(i) of the Loan Agreement is hereby
          amended and restated as follows:

          (i)  Indebtedness incurred pursuant to the Third and Fourth
               Amendments to the May 1998 Securities Purchase Agreement."

    3.24      The Loan Agreement is hereby amended to amend
          and restate clause (i) of the definition of
          "Impairment Event" in its entirety as follows:

          "(i) the existence of a Negative Equity Position,
             provided, however, that notwithstanding the
             requirements of GAAP, (A) any amounts
             outstanding under the 8% Subordinated Notes,
             (B) any amounts outstanding under any debt
             securities issued upon conversion or exchange
             of the Series G Preferred and (C) any amounts
             outstanding under the Company's 7.5%
             Convertible Subordinated Notes due July 1,
             2004 (including, without limitation, any Notes
             issued under the Fourth Amendment to the
             Securities Purchase Agreement) shall be
             considered to be equity for purposes of this
             clause only;".

    3.25      The Lender consents to the Company entering
into the Fourth Amendment to the Securities Purchase
Agreement and consummating the transactions contemplated
thereby including, without limitation, for the purpose of
Sections 7.7 and 7.12 of the Loan Agreement, as amended.

   IN WITNESS WHEREOF, the parties hereto have duly
   executed this Agreement as of the day and year first set
   forth above.

   ASCENT PEDIATRICS, INC.

   By:
       Name:
       Title:


   ALPHARMA USPD INC.

   By:
       Name:
       Title:


   ALPHARMA INC.

   By:
       Name:
       Title:


   STATE STREET BANK AND TRUST COMPANY

   By:
       Name:
       Title:



















                              September 24, 1999



Mr. Gert W. Munthe
Alpharma Inc.
One Executive Drive
Fort Lee, NJ 07024

Dear Mr. Munthe:

     Since you have informed Alpharma Inc. (the "Company") that
you desire to resign from the Company but are willing to remain
with the Company until the end of 1999, it is appropriate to set
forth the arrangements that will exist between the Company and
you following your resignation.  This letter agreement will
supersede, except to the extent expressly set forth herein, the
terms of the letter agreement dated February 26, 1998 between the
Company and you (the "1998 Employment Agreement") and set forth
such arrangements.  You will have the opportunity to review and
approve any press release or other public statement which
announces your decision to resign prior to the time such release
or statement is made public by the Company.  You will also have
the opportunity to review and approve any statement regarding
your resignation the Company proposes to include in any proxy
statement or other document required to be filed with the
Securities and Exchange Commission before such proxy statement or
other document is mailed to shareholders, filed or otherwise
communicated outside of the Company.

     1.   You resign all positions as officer, director and
          employee of the Company and each subsidiary of the
          Company effective on (a) December 31, 1999 or, if
          earlier and only as to positions as officer and
          director, (b) a date prior to December 31, 1999
          determined by the Compensation Committee of the
          Company's Board of Directors (such date of effective
          resignation being called the "effective date").  Prior
          to the effective date you will continue to hold the
          title of President and CEO of the Company and will
          perform such duties to the best of your ability as are
          assigned to you by the Chairman of the Office of the
          Chief Executive.

     2.   From the date hereof through December 31, 1999 (whether
          your resignation as officer and director is earlier or
          not), you will receive as compensation the salary and
          other benefits set forth pursuant to the 1998
          Employment Agreement.  For your agreements herein you
          will receive the following:

          a.   the amount of U.S.$10,000 per month commencing
               January, 2000, through December, 2001, in
               consideration of your agreements in paragraph 3;
               and
          b.   the amount of an additional U.S.$40,000 per month
               beginning January, 2000 through June, 2001 in
               consideration of your agreements in paragraph 4;
               and
          c.   a payment of U.S. $200,000 on or before February
               1, 2000 in lieu of any bonus under the 1998
               Employment Agreement; and
          d.   continued participation through December 31, 2001
               on the same basis as senior executives of the
               Company in the Company's life insurance program,
               disability insurance program, health and medical
               insurance program and tax and financial services
               planning (provided the Company may determine to
               reimburse you for your costs in obtaining
               comparable coverage in lieu of participation in
               any such insurance program); and
          e.   an automobile allowance of up to U.S. $15,000 per
               year for 2000 and 2001 plus insurance and
               maintenance;

          provided that if you become employed by or a partner in
          another entity prior to December 31, 2001, the
          compensation provided in clauses (d) (except for the
          tax and financial planning services contemplated by
          clause (d)) and (e) shall terminate at the end of the
          month in which such employment or partnership
          commences.  For this purpose employment in another
          entity shall be deemed to include becoming entitled to
          receive income for services rendered as an independent
          contractor in excess of U.S.$10,000 in any month.

          Unless otherwise legally required, all payments made
          under clauses (a), (b), (c), (d) or (e) of this
          paragraph 2 shall be in gross amounts and no
          withholding shall be taken from such payments.  You
          will receive a Form 1099 from the Company for all such
          payments.

     3.   You agree that following the effective date through
          December 31, 2001 you will provide such consultation to
          the senior officers of the Company as is requested from
          time to time by the Chairman or the CEO of the Company.
          The Company agrees that your services following the
          effective date shall not require you to provide
          services in a manner which conflicts with your personal
          schedule (including subsequent employment or consulting
          obligations) and you agree to use reasonable effort to
          respond to such request in a manner which does not
          disadvantage the Company.  The Company shall promptly
          reimburse you for any expenses you incur in performing
          any duties under this paragraph 3.
     4.   You agree that you shall not, during the period from
          now until June 30, 2001, (the "Restricted Period"),
          directly or indirectly engage in the business of
          producing, marketing or distributing generic
          pharmaceutical products or products for the animal
          health industry of the type currently produced or sold
          by the Company or its subsidiaries, and provided such
          business was engaged in by the Company or its
          subsidiaries prior to October 1, 1999, in any
          geographical area where such products are produced or
          sold by the Company or its subsidiaries.  Without
          limitation you agree not to provide services during the
          Restricted Period to Perrigo Pharmaceuticals, KV
          Pharmaceuticals, Morton Grove Laboratories, Barr
          Laboratories, Mylan Laboratories, Ivax, Teva
          Pharmaceuticals, Watson Pharmaceuticals, Pharmaceutical
          Resources or the Novartis generic subsidiary or Merck
          Darmstadt generic subsidiary or the animal health
          division of Pfizer, Hoffman-LaRoche or Smith Kline
          Beecham;  provided that it shall not be a violation of
          this paragraph 4 for you to directly or indirectly
          engage in (i) the business of sale through e-commerce
          of pharmaceuticals and related products or the business
          of development and commercialization of non-generic
          pharmaceutical products or (ii) any other businesses
          not described in this paragraph 4.

          For purposes of this agreement, each of the following
          activities, without limitation, shall be deemed to
          constitute engaging in a business:  to work with, be
          employed by, consult for, either individually, in
          partnership or in conjunction whether as principal,
          agent, employee, partner, director, officer or
          consultant, or in any other manner whatsoever, without
          or without compensation therefor.  Nothing contained in
          this agreement shall prohibit you from acquiring or
          holding as a passive investor less than five percent
          (5%) of the outstanding securities of any publicly
          traded company.

          The Company agrees not to make any statement at any
          time which disparages you or the services you have
          performed for the Company and you agree not to make any
          statement at any time which disparages the Company or
          its officers or employees.  Without limiting or
          affecting your Key Employee Agreement attached hereto,
          you agree to not disclose or use in any manner any
          information regarding the Company or its products,
          operations, technology or plans unless and until such
          information shall have become generally known to the
          public other than as a result of any disclosure or
          other action by you.

          You acknowledge and agree that the covenants set forth
          in this paragraph 4 are reasonable in scope, duration,
          geographic area and in all other respects.  You and the
          Company further agree that such covenants replace and
          supersede paragraph 10 of your Key Employee Agreement
          provided that all other provisions of such Key Employee
          Agreement shall continue.

          If any provision of this paragraph 4 shall be
          determined by any court of competent jurisdiction to be
          invalid, illegal or unenforceable in whole or in part,
          and such determination shall become final, such
          provision shall be deemed to be severed or limited, but
          only to the extent required to render the remaining
          provisions of this paragraph 4 enforceable.  This
          paragraph 4 as thus amended shall be enforced to give
          effect to the intention of the parties insofar as that
          is possible.

          You and the Company acknowledge and you agree that if
          you are found by a court of competent jurisdiction to
          have breached any covenant in this paragraph 4 all
          obligations of the Company to pay compensation to you
          under paragraph 2 of this Agreement of which this
          paragraph 4 is part shall terminate and the option
          which vests on July 8, 2001 shall not vest as provided
          in paragraph 6 below.  You and the Company further
          agree that in the event of any breach by either, the
          non-breaching party shall be entitled, in addition to
          its other rights and remedies, to enforce its rights
          under this Agreement by an action or actions for
          specific performance, injunction and/or other equitable
          relief in order to enforce or prevent any violations
          (whether anticipatory, continuing or future) of the
          provisions of this paragraph 4 (including, without
          limitation, the extension of the term of this paragraph
          4 by a period equal to (i) the length of the violation
          of this term plus (ii) the length of any court
          proceedings necessary to stop such violation.

     5.   The Company agrees that clause (iii) (to the extent it
          relates to relocation to Norway) and clause (iv) of
          paragraph 6 of the 1998 Employment Agreement shall
          continue provided that the Company's obligations under
          such clause (iv) shall terminate upon the earlier of
          (a) the sale of your current residence in New Jersey or
          (b) December 31, 2001.  You agree to use reasonable
          efforts to mitigate any cost to the Company under such
          clause (iv) and to make mutually satisfactory
          arrangements to release the Company from any
          obligations under such clause (iv) on December 31, 2001
          or such earlier date on which such residence is sold.
          The Company's obligations under clause (iii) shall
          terminate on December 31, 2001 (except for
          reimbursement of expenses incurred in relocating to
          Norway prior to such date).

     6.   All stock options granted to you shall continue in
          accordance with their terms (with vesting until the
          effective date), and such options which are exercisable
          on the effective date shall remain exercisable for two
          years following the effective date.  All options not
          vested and exercisable on the effective date shall not
          become vested and shall be forfeited on the effective
          date, except that options for 25,000 shares included in
          the option to acquire 100,000 shares granted to you on
          July 8, 1998, shall vest and become exercisable (until
          December 31, 2001) on July 8, 2001 provided you have
          not been found by a court of competent jurisdiction to
          have violated any provision of paragraph 4 of the
          agreement (it being understood that 50,000 shares of
          such option shall not vest and shall be forfeited).
     7.   If at any time after January 1, 2000 you intend to
          invest in an enterprise that is not engaged in a
          business which, in the good faith opinion of Kirkland &
          Ellis, would violate paragraph 4 hereunder and of which
          you intend to become an officer and employee, the
          Company will pay to you in a lump sum the sum of
          amounts payable to you under clause (b) of paragraph 2
          which then remain unpaid, discounted by the prime rate
          at Citibank then in effect.  Such lump sum payment will
          be made within 30 days after the Company receives a
          written notice from you confirming your intention as
          set forth in the prior sentence and nature of such
          investment.  You agree that a portion of such lump sum
          (consisting of amounts that would be payable following
          such violation if paid monthly as provided in paragraph
          2) shall be repaid by you as provided in paragraph 4 if
          you are found by a court of competent jurisdiction to
          have violated the provisions thereof.

     8.   The Company agrees to confirm the importance of your
          services hereunder and take other commercially
          reasonable efforts (not involving material cost to the
          Company) to enable your current visa (or other
          satisfactory visa or other arrangement to permit you to
          remain legally in the United States) to remain in
          effect through December 31, 2001 or your earlier
          relocation to Norway.


     If the foregoing accurately reflects our agreement, please
sign a counterpart of this agreement in the space provided below.

                              Sincerely,



                              Peter G. Tombros
                              Chairman of the Compensation
Committee
                              Chairman of the Stock Option
Committee




The foregoing is hereby agreed to:


                     Date:
Gert W. Munthe



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