XYTRONYX INC
8-K, 1996-12-27
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C. 20549
                                   
                                  FORM 8-K
                                  
                               CURRENT REPORT
                                  
                      Pursuant to Section 13 or 15(d) of
                      the Securities Exchange Act of 1934
                                  
                       Date of Report (Date of earliest
                               event reported):
                              December 19, 1996
                                  
                                  
                              XYTRONYX, INC.
                       --------------------------
            (Exact name of registrant as specified in its charter)
                                  
                                   DELAWARE
               (State or other jurisdiction of incorporation)
                 0-14838                         36-3258753
          ----------------------       ----------------------------
         (Commission File Number) (IRS Employer Identification Number)

                           6555 Nancy Ridge Drive
                                 Suite 200
                          SAN DIEGO, CALIFORNIA 92121
                 -----------------------------------------
            (Address of principal executive offices) (Zip Code)
                                  
     Registrant's telephone number, including area code:  (619) 550-3900
                                                          --------------
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Item 5.  Other Events.

    The News Release dated December 19, 1996 announcing that the Company had 
an initial closing in a private placement of equity securities to accredited 
individuals and institutional investors pursuant to Regulation D under the 
Securities Act of 1933, as amended, that the Company had hired Dr. H. 
Laurence Shaw to serve as the Company's new Chief Executive and President, 
that Jerry A. Weisbach has agreed to join the Company's Board of Officer 
Directors and Scientific Advisory Board, and that David W. Golde, M.D. has 
agreed to joint the Company as Chairman of the Scientific Advisory Board 
filed as Exhibit 99.1 hereto, is hereby incorporated into this Report by 
reference.

Item 7.  Financial Statements, Pro Forma Financial Information and Exhibits.

               (c)  EXHIBITS.  The following exhibit accompanies this Report:

               EXHIBIT
               NUMBER                        EXHIBIT DESCRIPTION
              ---------                      -------------------
                99.1       News Release dated December 19, 1996 announcing that
                           the Company had an initial closing in a private 
                           placement of equity securities to accredited 
                           individuals and institutional investors pursuant to 
                           Regulation D under the Securities Act of 1933, as 
                           amended, that the Company had hired Dr. H. Laurence
                           Shaw to serve as the Company's new Chief Executive 
                           Officer and President, that Jerry A. Weisbach has 
                           agreed to join the Company's Board of Directors and 
                           Scientific Advisory Board, and that David W. Golde, 
                           M.D. has agreed to joint the Company as Chairman of 
                           the Scientific Advisory Board.  






                                  SIGNATURES
                                           
    Pursuant to the requirements of the Securities Exchange Act of 1934, the 
registrant has duly caused this report to be signed on its behalf by the 
undersigned hereunto duly authorized.

                                              XYTRONYX, INC.



                                              By: /S/ LARRY O. BYMASTER
                                                  ---------------------
                                                      Larry O. Bymaster
                                                      Chief Executive Officer


Date:  December 27, 1996

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<PAGE>

                                INDEX TO EXHIBITS



 EXHIBIT                                                         SEQUENTIALLY
 NUMBER                     DESCRIPTION OF EXHIBIT               NUMBERED PAGE
- --------                    ----------------------               -------------

 99.1       News Release dated December 19, 1996 announcing that
            the Company had an initial closing in a private 
            placement of equity securities to accredited 
            individuals and institutional investors pursuant to
            Regulation D under the Securities Act of 1933, as
            amended, that the Company had hired Dr. H. Laurence 
            Shaw to serve as the Company's new Chief Executive 
            Officer and President, that Jerry A. Weisbach has 
            agreed to join the Company's Board of Directors and
            Scientific Advisory Board, and that David W. Golde, 
            M.D. has agreed to joint the Company as Chairman of 
            the Scientific Advisory Board.

                                       3


<PAGE>

FOR IMMEDIATE RELEASE

CONTACT: Larry Bymaster, Chief Executive Officer-Pro Tem
         Laurence Shaw
         (619) 550-3900

________________________________________________________________________________

                XYTRONYX, INC. ANNOUNCES ELECTION OF NEW CHIEF
                  EXECUTIVE OFFICER, APPOINTMENT OF TWO NEW
                   DIRECTORS AND PRIVATE PLACEMENT CLOSING
                                           
    SAN DIEGO, CA, December 19, 1996 -- Xytronyx, Inc. (AMEX: XYX) today 
announced that it had hired Dr. H. Laurence Shaw to serve as the Company's 
new Chief Executive Officer and President, and that it closed on a net amount 
of $2,910,150 in an initial closing of its Private Placement.  The proceeds 
received in the initial closing represent funds which will allow the Company 
to continue as a going concern into 1997.  Additionally, Jerry A. Weisbach 
has agreed to join the Company's Board of Directors and Scientific Advisory 
Board, and David W. Golde, M.D. has agreed to join the Company as Chairman of 
the Scientific Advisory Board.  

    The closing on the $2,910,150 (gross of $3,345,000) represents the first 
closing in a Private Placement of Units at a price per Unit of $100,000, each 
Unit consisting of 500 shares of Preferred Stock, par value $25.00 per share, 
stated value $200.00 per share, and 50,000 Common Stock Purchase Warrants, to 
accredited individuals and institutional investors pursuant to Regulation D 
under the Securities Act of 1933, as amended.  The maximum proposed offering 
amount of 100 Units would represent aggregate proceeds of $10 million, 
subject to an additional overallotment option of 25 Units. Each share of 
Preferred Stock may be converted at the option of the holder at the lowest of 
80% of the average closing bid price of the Company's Common Stock on AMEX 
for the thirty consecutive trading days immediately preceding the date of any 
closing in the Private Placement.  In addition, the Conversion Price is 
subject to further adjustment on the date which is twelve months after the 
final closing date if the average closing bid price of the Common Stock for 
the thirty consecutive trading days immediately preceding that date is less 
than 130% of the Conversion Price as adjusted, subject to a limit on the 
number of shares that may be issued pursuant to such reset.  Each Warrant 
entitles the holder to purchase one share of Common Stock at a price of $1.00 
per share and may be exercised until November 26, 2005.  The Company expects 
the Private Placement to be completed in or about January, 1997 but in any 
event no later than March, 1997.

    "I am very excited to have the opportunity to help shape the future of a 
Company with several promising technologies" said Dr. Shaw.  "With the 
consummation of the Private Placement financing and the involvement of Drs. 
Weisbach and Golde in the development of the Company's technology, I believe 
the Company will be in an excellent position to realize its great potential." 
Mr. Bymaster said "I look forward to working closely with Dr. Shaw and am 
pleased to continue to play a part in the ongoing positive development of the 
Company." Mr. Bymaster, the present CEO and President, will take on a new 
position with the primary responsibility of overseeing the Company's PTM and 
Kephra product lines.

    The Company intends to use the proceeds from the Private Placement for 
the payment of accrued liabilities, completion of preclinical development of 
its cancer therapies, working capital for general corporate purposes and for 
the repayment of certain indebtedness.

    Prior to joining the Company, Dr. Shaw served as Corporate Vice President 
Research Development of C.R. Bard.  Prior to that, from 1993-1995, he served 
as Chief Executive Officer, President and Director of Atlantic 
Pharmaceuticals, Inc. and from 1984-1993, he was Vice President, Medical and 
Regulatory Affairs and Advanced Research at Abbott Laboratories.  Dr. Shaw 
has also held positions at Revlon Health Care Ltd., Merck and Smithkline 
Corporation.  Dr. Shaw is a graduate of the University College Hospital 
Medical School, London, UK and is a Fellow of the faculty of Pharmaceutical 
Medicine of the Royal College of Physicians, a Fellow of the American College 
of Clinical Pharmacology, and a member of many professional associations.  

                                       4
<PAGE>

    Dr. Weisbach is a member of the Board of Directors of Hybridon, Inc., 
Cima Labs, Xenometrix, Inc., Synthon Corporation and Neose Technologies, Inc. 
and is a member of the Scientific Advisory Boards of Magainin 
Pharmaceuticals, Chemgenics, Inc. and AVAX Technologies, Inc. Dr. Weisbach is 
a former Vice President of Warner-Lambert Company and President of its 
Pharmaceutical Research Division where, from 1979 to 1987, he was responsible 
for all pharmaceutical research and development activities of Warner-Lambert. 
Prior to joining Warner-Lambert in 1979, Dr. Weisbach served at Smith Kline 
and French Laboratories from 1960 to 1979, where he was Vice President, 
Research from 1977 to 1979.  From 1988 to 1994, he was Director of Technology 
Transfer and continues as Adjunct Professor at Rockefeller University.  Dr. 
Weisbach received his Ph.D. in Chemistry from Harvard University.

    David W. Golde, M.D. is Physician-in-Chief, Memorial Hospital, Memorial 
Sloan-Kettering Cancer Center in New York and holder of the Enid A. Haupt 
Chair in Hematologic Oncology.  Dr. Golde is also a Professor of Medicine at 
Cornell University Medical College, a Professor of Molecular Pharmacology and 
Therapeutics at Cornell University Graduate School of Medical Sciences, a 
Member of the Sloan-Kettering Institute, and an Attending Physician at 
Memorial Hospital.  Dr. Golde has authored more than 400 scientific and 
medical publications.  Dr. Golde received an M.D., C.M. from McGill 
University and a B.S. in Chemistry from Fairleigh Dickinson University.

    Additionally, the Board of Directors of the Company has authorized 
management to take steps to consummate the proposed merger with Binary 
Therapeutics, Inc. and to increase the amount of authorized shares of Common 
Stock to 100 million shares, each of which will be subject to prior 
shareholder approval.

    The securities offered or sold in the Private Placement have not have 
been registered under the Securities Act of 1933, as amended, or applicable 
state securities laws, at the time of the Private Placement and may not be 
offered or sold absent registration under the Securities Act and applicable 
state securities laws or available exemptions from registration.

    The statements made in this press release contain certain forward-looking 
statements within the meaning of Section 27A of the Securities Act of 1933 
and Section 21E of the Securities Act of 1934 that involve a number of risks 
and uncertainties, including the risk that the Company will be unable to 
complete the proposed Private Placement to receive sufficient funding to 
fully effect its current plans.  Among other things, Dr. Shaw has the right 
to terminate his employment contract if the Company does not close on gross 
proceeds of $7.5 million in the Private Placement.  Actual events or results 
may differ from Xytronyx's expectations.  In addition to the matters 
described in this press release, risk factors listed from time to time in 
Xytronyx's SEC reports, including, but not limited to, its report on Form 
10-Q for the quarter ended September 30, 1996 as well as its Annual Report on 
Form 10-K, may effect the results achieved by Xytronyx.

    Xytronyx, Inc. is engaged in the development and commercialization of 
medical products with a primary focus on cancer treatment.

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