PACIFIC PHARMACEUTICALS INC
10-Q, 1999-02-12
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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<PAGE>




                                     FORM 10-Q
                         SECURITIES AND EXCHANGE COMMISSION
                                          
                               Washington D.C.  20549
                                          
                                          
                     Quarterly Report Under Section 13 or 15(d)
                       of the Securities Exchange Act of 1934
                      for the Quarter Ended December 31, 1998
                           Commission file number 1-9613
                                          
                                          
                           Pacific Pharmaceuticals, Inc.
               ------------------------------------------------------
               (Exact name of registrant as specified in its charter)
                                          
                                          
                                          
                                          
           Delaware                                    36-3258753
      ------------------------------------------------------------------------
     (State of incorporation)              (I.R.S. Employer Identification No.)
                                          
                                          
                                          
                                          
        6730 Mesa Ridge Road, Suite A, San Diego, CA             92121
      ------------------------------------------------------------------------
          (Address of principal executive offices)             (Zip  Code)
        


                                     (619) 550-3900
      ------------------------------------------------------------------------
                (Registrant's Telephone number, including area code)
                                          
                                          
                                          
                                          
                                          

Indicate by check mark whether the registrant (1) has filed all reports 
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 
1934 during the preceding 12 months (or for such shorter period that the 
registrant was required to file such reports) and (2) has been subject to 
such filing requirements for the past 90 days.   Yes   X   No 
                                                      ----     -----

As of February 11, 1999, there were  14,671,924 shares of the registrant's 
Common Stock, $.02 par value outstanding.


<PAGE>


                   PACIFIC PHARMACEUTICALS, INC. AND SUBSIDIARIES
                          (A DEVELOPMENT STAGE ENTERPRISE)
                           INCORPORATED DECEMBER 23, 1983
                                          
                                          
                                          
                                       INDEX
                                          
Cautionary Statement Under the Private Securities 
Litigation Reform Act of 1995. . . . . . . . . . . . . . . . . . . . . . . . 1
                                          
PART I - FINANCIAL INFORMATION

     Item 1.   Consolidated Financial Statements:
     
               Consolidated Balance Sheets -
               December 31, 1998 and March 31, 1998  . . . . . . . . . . . . 2

               Consolidated Statements of Operations -
               Three Months and Nine Months Ended 
               December 31, 1998 and 1997 (as restated)
               and from September 23, 1983 (inception) to
               December 31, 1998 . . . . . . . . . . . . . . . . . . . . . . 3

               Consolidated Statements of Stockholders'
               Equity/(Deficiency)-Nine Months Ended 
               December 31, 1998 and 1997 (as restated). . . . . . . . . . . 4
     
               Consolidated Statements of Cash Flows -
               Nine Months Ended December 31, 1998 and 1997
               and from September 23, 1983 (inception) to
               December 31, 1998 . . . . . . . . . . . . . . . . . . . . . . 5
     
               Notes to Consolidated Financial Statements. . . . . . . . . . 6
     
     Item 2.   Management's Discussion and Analysis of
               Financial Condition and Results of Operations . . . . . . . .11


PART II - OTHER INFORMATION

     Item 5.   Proposed Merger . . . . . . . . . . . . . . . . . . . . . . .15

     Item 6.   Exhibits and Reports on Form 8-K. . . . . . . . . . . . . . .15

SIGNATURE      . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .16


<PAGE>
                                          
 CAUTIONARY STATEMENT UNDER THE PRIVATE SECURITIES LITIGATION REFORM ACT OF 1995
                                          
                                          
Statements in this Quarterly Report on Form 10-Q under the caption 
"Management's Discussion and Analysis of Financial Condition and Results of 
Operations" in the "Notes to Consolidated Financial Statements", and in Item 
5, "Proposed Merger", as well as oral statements that may be made by the 
Company or by officers, directors or employees of the Company acting on the 
Company's behalf, that are not historical fact constitute "forward-looking 
statements" within the meaning of Section 27A of the Securities Act of 1933, 
as amended, and Section 21E of the Securities Exchange Act of 1934, as 
amended.  These forward-looking statements involve risks and uncertainties, 
including, but not limited to, the risk that the Company may not be able to 
obtain additional financing, if necessary; the risk that the Company may not 
be able to continue the necessary development of its operations on a 
profitable basis, or that the merger between the Company and Procept, Inc. 
will be consummated and, if consummated, be successful.  In addition, the 
Company's business, operations and financial condition are subject to reports 
and statements filed from time to time with the Securities and Exchange 
Commission, including the Company's Annual Report on Form 10-K/A for the 
fiscal year ended March 31, 1998 and this Quarterly Report on Form 10-Q.




                                       1
<PAGE>


PACIFIC PHARMACEUTICALS, INC. AND SUBSIDIARIES (A Development Stage Enterprise)

CONSOLIDATED BALANCE SHEETS (unaudited)

<TABLE>
<CAPTION>

                                                                                   December 31, 1998       March 31, 1998
- -----------------------------------------------------------------------------------------------------------------------------
<S>                                                                                    <C>                  <C>
ASSETS
Current Assets:
Cash and cash equivalents                                                               $3,561,557           $3,290,176
Accounts receivable, net                                                                    15,236                    -
Inventory                                                                                        -               38,637
Prepaid expenses                                                                            63,261               85,053
- -----------------------------------------------------------------------------------------------------------------------------
       Total current assets                                                              3,640,054            3,413,866

Property and equipment, net                                                                 48,050               71,840
Patent costs, net                                                                          105,322              104,981
- -----------------------------------------------------------------------------------------------------------------------------
TOTAL ASSETS                                                                            $3,793,426           $3,590,687
- -----------------------------------------------------------------------------------------------------------------------------


LIABILITIES AND STOCKHOLDERS' EQUITY
Current Liabilities:
Accounts payable                                                                        $  654,271           $  661,371
Accrued expenses                                                                           476,864              201,125
Current portion of capital leases                                                            4,381                4,066
- -----------------------------------------------------------------------------------------------------------------------------
       Total current liabilities                                                         1,135,516              866,562
- -----------------------------------------------------------------------------------------------------------------------------

Capital leases                                                                              19,261               22,584
Minority interest                                                                        4,665,323                    -
- -----------------------------------------------------------------------------------------------------------------------------

Stockholders' Equity/(Deficiency):
Convertible preferred stock, $25 par value, 2,000,000 shares authorized;
       36,196 and 40,090 issued and outstanding at December 31,1998
       and March 31, 1998, respectively                                                    904,938            1,002,288
       (liquidation preference $9,410,960 and $10,423,400, respectively)
Common stock, $.02 par value, 100,000,000 shares authorized;
       12,513,656 and 10,777,234 shares issued and outstanding at
       December 31, 1998 and March 31, 1998, respectively                                  250,269              215,545
Capital in excess of par value                                                          48,384,983           46,969,197
Deficit accumulated during the development stage                                       (51,566,865)         (45,485,489)
- -----------------------------------------------------------------------------------------------------------------------------
       Total stockholders' equity/(deficiency)                                          (2,026,674)           2,701,541
TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY/(DEFICENCY)                                  $3,793,426          $ 3,590,687
- -----------------------------------------------------------------------------------------------------------------------------
</TABLE>

SEE NOTES TO CONSOLIDATED FINANCIAL STATEMENTS.


                                       2

<PAGE>


PACIFIC PHARMACEUTICALS, INC. AND SUBSIDIARIES (A Development Stage Enterprise)

CONSOLIDATED STATEMENTS OF OPERATIONS (unaudited)

<TABLE>
<CAPTION>


                                     Three Months Ended                        Nine Months Ended    
                                  --------------------------------    ------------------------------------       September 23, 1983
                                        December 31                                December 31                     (inception) to
                                  1998                1997                  1998                 1997             December 31, 1998
- ------------------------------------------------------------------    --------------------------------------------------------------
<S>                               <C>               <C>                   <C>               <C>                       <C>
REVENUES                                            (as restated)                            (as restated)
   Product sales              $      2,120        $     68,810         $      6,136        $     69,510             $   2,025,877
   License fees and royalties            -                 145                    -                 332                   486,612
   Contract research                     -                   -                    -                   -                   268,063
   Marketing rights                      -                   -                    -                   -                 1,311,500
   Interest and other               50,609              59,175              149,963             224,834                 2,063,621
- ------------------------------------------------------------------    ------------------------------------   ---------------------
Total revenues                      52,729             128,130              156,099             294,676                 6,155,673
- ------------------------------------------------------------------    ------------------------------------   -----------------------
COSTS AND EXPENSES
   Cost of product sales            13,497              87,471               41,075             122,792                 3,179,470
   Product development             331,856             411,042            1,312,324           1,433,306                18,473,285
   General and administrative      812,724             474,538            1,590,292           1,672,782                19,442,039
   Business development
     and marketing                   4,345              36,888               26,901             159,128                 3,803,790
   Interest and other              112,963               1,598              131,585              55,725                   765,560
- ------------------------------------------------------------------    ------------------------------------   -----------------------
Total costs and expenses         1,275,385           1,011,537            3,102,177           3,443,733                45,664,144
- ------------------------------------------------------------------    ------------------------------------   -----------------------
Loss applicable to
  minority interest                 73,608                   -              159,083                   -                   159,083

Net loss                        (1,149,048)           (883,407)          (2,786,995)         (3,149,057)              (39,349,388)
- ----------------------------------------------  ------------------    --------------------------------------------------------------
Convertible preferred stock
   dividends                             -             932,170            3,294,381           4,360,158                12,217,477

Net loss applicable to
   common shareholders        $ (1,149,048)       $ (1,815,577)        $ (6,081,376)       $ (7,509,215)            $ (51,566,865)
- ------------------------------------------------------------------    --------------------------------------------------------------
Net loss per share of common
    stock-basic and diluted         ($0.09)             ($0.18)              ($0.52)             ($0.84)
- ------------------------------------------------------------------    ------------------------------------
Weighted average common
   stock outstanding            12,356,069           9,986,058           11,681,950           8,906,236
- ------------------------------------------------------------------    ------------------------------------
</TABLE>

SEE NOTES TO CONSOLIDATED FINANCIAL STATEMENTS.


                                       3

<PAGE>


PACIFIC PHARMACEUTICALS, INC. AND SUBSIDIARIES (A Development Stage Enterprise)

CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY/(DEFICIENCY) (unaudited)

<TABLE>
<CAPTION>




                                                                                                             Deficit
                                                                                                           Accumulated
                                 Convertible Preferred Stock         Common Stock           Capital        During the
                                 ----------------------------    ----------------------    in Excess       Development
                                 Shares         Par Value       Shares     Par Value      of Par Value        Stage        Total
- -----------------------------------------------------------------------------------------------------------------------------------
<S>                              <C>          <C>               <C>        <C>           <C>              <C>            <C>
Balance at March 31, 1997
  (as restated)                  50,000       $1,250,038        8,151,029   $163,021     $38,805,489     ($33,887,139) $ 6,331,409
Exercise of warrants                                              420,312      8,406         386,687                       395,093
Issuance of common stock
  for services                                                      1,143         20             980                         1,000
Conversion of preferred
  stock into common stock        (8,394)        (209,850)       1,748,753     34,975         174,875                             -
Preferred stock unit purchase
  option compensation for
  financial advisory services                                                                248,666                       248,666
Convertible preferred stock
  dividends (as restated)                                                                  4,360,158       (4,360,158)           -
Net loss                                                                                                   (3,149,057)  (3,149,057)
- -----------------------------------------------------------------------------------------------------------------------------------
Balance at December 31, 1997
  (as restated)                  41,606       $1,040,188       10,321,237   $206,422     $43,976,855      ($41,396,354) $3,827,111
- -----------------------------------------------------------------------------------------------------------------------------------
- -----------------------------------------------------------------------------------------------------------------------------------

Balance at March 31, 1998        40,090       $1,002,288       10,777,234   $215,545     $46,969,197      ($45,485,489) $2,701,541
Exercise of warrants                                                1,563         31           1,438                         1,469
Common stock issued for services                                  571,172     11,423         251,194                       262,617
Preferred stock unit purchase
  option as compensation for
  financial advisory services                                                                138,165                       138,165
Conversion of preferred stock
  into common stock              (3,894)         (97,350)       1,163,687     23,270          74,080                             -
Convertible preferred
  stock dividends                                                                            374,056        (3,294,381) (2,920,325)
Proceeds from subsidiary
  preferred stock issuance                                                                   576,853                       576,853
Net loss                                                                                                    (2,786,995) (2,786,995)
- -----------------------------------------------------------------------------------------------------------------------------------
Balance at December 31, 1998     36,196         $904,938       12,513,656   $250,269     $48,384,983      ($51,566,865)($2,026,674)
- -----------------------------------------------------------------------------------------------------------------------------------
- -----------------------------------------------------------------------------------------------------------------------------------
</TABLE>
SEE NOTES TO CONSOLIDATED FINANCIAL STATEMENTS.


                                       4

<PAGE>


PACIFIC PHARMACEUTICALS, INC. AND SUBSIDIARIES (A Development Stage Enterprise)

CONSOLIDATED STATEMENTS OF CASH FLOWS (unaudited)

<TABLE>
<CAPTION>

                                                                Nine Months Ended 
                                                                   December 31                  September 23, 1983
                                                           ----------------------------           (inception) to
                                                            1998                  1997           December 31, 1998
- ---------------------------------------------------------------------------------------         ------------------
<S>                                                         <C>            <C>                    <C>
OPERATING ACTIVITIES
Net loss                                                    ($2,786,995)   ($3,149,057)           ($39,349,386)
Adjustments to reconcile net loss to net cash
  used by operating activities:
     Depreciation and amortization                               53,357         62,742               1,718,358
     Loss allocated to minority interest                       (159,083)             -                (159,083)
     Non-cash expense upon issuance of common stock
         options, common stock and warrants                     400,782        248,666               1,252,643
     Net book value of asset disposals                           70,871         58,534                 312,563
     Option income from retirement of stock
         or amounts previously advanced by customer                   -              -                (400,000)
     Changes in assets and liabilities:
         Accounts receivable                                    (15,236)        23,996                 (15,236)
         Inventory                                               38,637          3,040                       -
         Prepaid expenses and other assets                       21,792        (20,311)                (74,236)
         Accounts payable                                        (7,100)      (486,751)                654,271
         Accrued expenses                                       275,739         87,647                 332,841
         Customer advances                                            -              -                 140,863
         Other liabilities                                            -          1,506                  (4,869)
- --------------------------------------------------------------------------------------  -------------------------
     Net cash used by operating activities                   (2,107,236)    (3,169,988)            (35,591,271)

INVESTING ACTIVITIES
Purchases of short-term investments                                   -              -             (10,461,867)
Maturities of short-term investments                                  -      1,484,788              10,461,867
Capital expenditures                                             (6,213)       (16,637)               (854,142)
Patent costs                                                    (94,566)       (58,321)             (1,071,938)
Other                                                               316              -                   8,145
- --------------------------------------------------------------------------------------  -------------------------
     Net cash provided (used) by investing activities          (100,463)     1,409,830              (1,917,935)

FINANCING ACTIVITIES
Issuance of notes payable                                             -              -               2,183,867
Repayment of notes payable                                            -              -              (1,965,124)
Repayment of capital lease obligations                           (3,324)        (3,592)               (186,871)
Long-term customer advances                                           -              -                 100,000
Issuance of common and preferred stock                          578,322        396,093              39,034,809
Minority interest investment in subsidiary                    1,904,082              -               1,904,082
- --------------------------------------------------------------------------------------  -------------------------
     Net cash provided by financing activities                2,479,080        392,501              41,070,763
- --------------------------------------------------------------------------------------  -------------------------
Net increase (decrease) in cash
     and cash equivalents                                       271,381     (1,367,657)              3,561,557
Cash and cash equivalents at beginning of period              3,290,176      1,784,599                       -
- --------------------------------------------------------------------------------------  -------------------------
Cash and cash equivalents at end of period                   $3,561,557       $416,942              $3,561,557
- --------------------------------------------------------------------------------------  -------------------------
</TABLE>

SEE NOTES TO CONSOLIDATED FINANCIAL STATEMENTS.


                                       5

<PAGE>


                   PACIFIC PHARMACEUTICALS, INC. AND SUBSIDIARIES
                          (A DEVELOPMENT STAGE ENTERPRISE)
                                          
               NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (UNAUDITED)

1.  PRINCIPLES OF INTERIM PERIOD REPORTING

The consolidated financial statements include the accounts of Pacific 
Pharmaceuticals, Inc. and its wholly owned subsidiaries, Perio Test, Inc., 
XYX Acquisition Corp. and BG Development Corp., a majority owned subsidiary, 
(collectively the "Company"). All significant intercompany balances and 
transactions have been eliminated.
 
The Company has not earned significant revenues from planned principal 
operations.  Accordingly, the Company's activities have been accounted for as 
those of a "Development Stage Enterprise" as set forth in Financial 
Accounting Standards Board Statement No. 7 ("FAS 7"). Among the disclosures 
required by FAS 7 are that the Company's financial statements be identified 
as those of a development stage enterprise, and that certain consolidated 
financial statements disclose activity since the date of the Company's 
inception.

The preparation of financial statements in conformity with generally accepted 
accounting principles requires management to make estimates and assumptions 
that affect the reported amount of assets and liabilities and disclosure of 
contingent assets and liabilities at the date of the financial statements and 
the reported amounts of revenues and expenses during the period.  Actual 
results may differ from those estimates.

In the opinion of the Company, the unaudited consolidated financial 
statements contain all of the adjustments, consisting only of normal 
recurring adjustments and accruals, necessary to present fairly the financial 
position of the Company as of December 31, 1998 and March 31, 1998, results 
of operations for the nine months ended December 31, 1998 and 1997 (as 
restated) and from September 23, 1983 (inception) to December 31, 1998 and 
cash flows for the nine months ended December 31, 1998 and 1997 and from 
September 23, 1983 (inception) to December 31, 1998. The results of 
operations for the nine months ended December 31, 1998 are not necessarily 
indicative of the results to be expected in subsequent periods or for the 
year as a whole.  For further information, refer to the consolidated 
financial statements and footnotes thereto as set forth in the Company's 
Annual Report on Form 10-K and 10-K/A for the year ended March 31, 1998.

The Company adopted Financial Accounting Standards Board Statement No. 128 
("FAS 128"), EARNINGS PER SHARE (EPS). This statement requires the 
presentation of earnings per share to reflect both "Basic EPS" as well as 
"Diluted EPS" on the face of the statement of operations. In general, Basic 
EPS is a function of weighted average number of common shares outstanding for 
the periods. Diluted EPS does reflect the potential dilution created by stock 
issuable pursuant to outstanding options, warrants, convertible debt or 
equity securities and other contingently issuable shares. The requirements of 
FAS 128 have been applied retroactively to all periods presented. There was 
no impact on reported net loss per common share as a result of the adoption 
of this FAS.


                                       6

<PAGE>


2. BGDC PRIVATE PLACEMENT FINANCING AND MINORITY INTEREST 

During the nine months ended December 31, 1998, the Company entered into a 
placement agency agreement with Paramount Capital Inc. ("Paramount). Under 
the terms of the agreement, Paramount was to use its best efforts to sell up 
to 60 Units ( with an overallotment option for an additional 40 Units) for 
$100,000 per unit, which consist of 50,000 shares of Series A Convertible 
Preferred Stock ("BGDC Units"), valued at $2.00 per share of BG Development 
Corp. ("BGDC"). The BGDC Units are redeemable in cash  by BGDC and the BGDC 
Units may be exchanged for cash or common stock of the Company under the 
circumstances described in the subscription agreement between the Company and 
shareholders of BGDC. Pursuant to the subscription agreement, seventy-five 
percent of the net proceeds are allocated to BGDC for development costs 
associated with O6 Benzylguanine technology. Twenty-five percent of the net 
proceeds of the BGDC private placement went to the Company to be used for 
general purposes. 

The BGDC Units accrue dividends as follows:

                 Dividend Date              Dividend Amount
           --------------------------      ----------------
           Upon final closing              $1.99 per share
           30-36 months after closing      $0.82 per share
           36-42 months after closing      $0.82 per share
           42-48 months after closing      $1.16 per share
           48-60 months after closing      $1.16 per share
           After 60 months                 Compounded rate of 35%

On June 22, 1998, the Company completed a closing on 29.35 BGDC Units of the 
private placement for gross proceeds of $2,900,000 (net proceeds of 
$2,455,000). Paramount, who is affiliated with certain significant 
shareholders of the Company, received an aggregate dollar commission of 
$264,000 and a non-accountable expense allowance of $117,000 as compensation 
for the BGDC private placement. Additionally, Paramount received warrants to 
purchase 10% of the number of BGDC Units issued in the private placement at 
$110,000 per unit. BGDC and Paramount also entered into a 24 month Financial 
Advisory Services Agreement in which BDGC will pay Paramount $3,000 per month 
for such services plus warrants ("Advisory Warrants") to purchase 15% of the 
number of BGDC Units issued in the private placement at $110,000 per Unit. 
The Company valued the Advisory Warrants at $88,000 and is amortizing these 
advisory services over a 24 month period ending in June 2000.

Subsequent to the closing of the private placement, BGDC Preferred 
Stockholders own 16.4% of voting rights in BGDC. This minority interest, as 
reflected in the accompanying Consolidated Balance Sheet as of December 31, 
1998, includes the initial net proceeds to BGDC of $1,886,000, plus the 
initial dividend of $2,920,000, or $1.99 per preferred share outstanding, 
paid in capital associated with the amortization of the Advisory Warrants and 
16.4% of BGDC's operating loss through December 31, 1998.

BGDC and the Company have entered into a one-year renewable Corporate 
Services and Management Agreement pursuant to which the Company will provide 
financial/accounting, administrative, advisory and managerial support to 
BGDC. For such services, the Company will receive from BGDC a management fee 
equal to $500,000 per year, payable in equal monthly installments. The 
Company does not expect any further closings to occur for the private 
placement.


                                       7

<PAGE>


3.  TERMINATION OF PTM PRODUCT

During the quarter ended December 31, 1998, the Company determined that it 
would no longer continue to sell its Periodontal Tissue Monitor ("PTM") 
product. In that connection, the Company recorded an expense of  $113,000, 
which consists of the following:

                                      Amount
                                     -------
           Inventory                  $55,000
           Unamortized patent costs    58,000
                                     --------
                              Total  $113,000
                                     --------

4. NON-CASH CONVERTIBLE PREFERRED STOCK DIVIDENDS

In fiscal year 1997, the Company completed a private equity financing ("1997 
Private Placement") in two stages with the initial closing completed on 
December 19, 1996 (the "Initial Closing") and the final closing completed on 
March 7, 1997 (the "Final Closing") in which it raised $8,542,000, net of 
offering expenses. 

The Company sold 100 Premium Preferred Units ("Units") at a price per Unit of 
$100,000, each Unit consisting of 500 shares of Convertible Preferred Stock 
("Preferred Stock"), par value $25 per share, and 50,000 detachable Common 
Stock Purchase Warrants ("Warrants"), to accredited individuals and 
institutional investors pursuant to Regulation D under the Securities Act of 
1933, as amended. Each Warrant entitles the holder to purchase one share of 
Common Stock at a price of $1 per share and may be exercised until March 7, 
2007. 

The initial conversion ratio for the Preferred Stock was 208.33 shares of 
Common Stock for each share of Preferred Stock. The 1997 Private Placement 
contained an adjustment provision to reset the conversion ratio under certain 
conditions. For Preferred Stock converted after March 7, 1998, the new 
conversion ratio is 290.89 shares of common stock for each share of Preferred 
Stock.

The subscribers to the Private Placement purchased the Units at a discount 
from the closing prices of the Company's common stock on the Initial Closing 
date of 23% and the Final Closing date of 36%. The detachable stock purchase 
warrants issued as part of the Units had a fair value at the date of issuance 
of $1,967,000. The aggregate value of the beneficial conversion feature and 
warrants at the date of issuance was $6,721,000 and has been recognized as a 
return to the Preferred Stockholders from the date of issuance of the 
Preferred Stock to the date in which the Preferred Stock was eligible for 
conversion into Common Stock. The reset of the conversion ratio during March 
1998 generated an additional non-cash dividend of $2,576,000.

As discussed in Note 2, the BGDC private placement includes a provision that 
the subscribers are entitled to receive $1.99 per share dividends declared by 
to Board of Directors of BGDC. The dividends of $2,920,000, which have been 
credited to minority interest during the nine months ended December 31, 1998, 
accumulate until paid in cash or common stock by BGDC.


                                       8

<PAGE> 


Below is a summary of Preferred Stock Dividends recognized during the periods 
indicated:

<TABLE>
<CAPTION>

                                   Three Months Ended December 31,  Nine Months Ended December 31,       September 23, 1983
                                   -------------------------------  -----------------------------          (inception) to
Description                              1998            1997             1998             1997           December 31, 1998
                                        ------          ------           ------           ------         ------------------
                                                     (as restated)                    (as restated)
<S>                                      <C>          <C>                <C>          <C>                       <C>
Dividend from beneficial
   Conversion feature                     -            665,786             128,036     3,114,179                  4,754,075
Dividend from reset of conversion         -                  -             194,752             -                  2,576,077
Dividend from warrant valuation           -            266,384              51,268     1,245,979                  1,967,000
BGDC Preferred Stock dividends            -                  -           2,920,325             -                  2,920,325
                                        ------         -------           ---------     ---------                 ----------
                             Total        -            932,170           3,294,381     4,360,158                 12,217,477
                                        ------         -------           ---------     ---------                 ----------
</TABLE>

5.   1997 RESTATEMENT  

Subsequent to the issuance of the Company's 1997 financial statements, the 
Company's management determined that the accounting for the convertible 
Preferred Stock issued during the fiscal year did not reflect the value of 
the detachable stock purchase warrants issued in connection with the 1997 
Private Placement described in Note 4. The fair value of such warrants, as 
calculated by an independent valuation consulting firm, was $1,967,000, and 
has been recorded as a return to the Preferred Stockholders from the date of 
issue of the Preferred Stock to the date in which the Preferred Stock was 
eligible for conversion into Common Stock. As a result, net loss applicable 
to Common Shareholders and net loss per share for the quarter ended December 
31, 1997 and nine months ended December 31, 1997 have been restated from the 
amounts previously reported. Such restatement resulted in increases of 
$461,000 and $980,000 in both capital in excess of par value and the deficit 
accumulated in development stage for the quarter and nine months ended 
December 31, 1997, respectively. 

A summary of the effect of the restatement is as follows:

<TABLE>
<CAPTION>

                             Quarter                        Nine Months
                              ended          Quarter           ended         Nine Months
                          December 31,        Ended        December 31,         Ended
                              1997        December 31,         1997         December 31,
                          As Previously       1997         As Previously        1997
                            Reported       As Restated       Reported        As Restated
                          -------------   ------------     -------------    --------------
<S>                       <C>             <C>              <C>              <C>
Convertible
  Preferred stock
  Dividends                $   665,786     $   932,170      $ 3,114,179      $  4,360,158
                          -------------   ------------     -------------    --------------
Net loss applicable
  To common
  Shareholders             $(1,549,193)    $(1,815,577)     $(6,263,236)     $ (7,509,215)
                          -------------   ------------     -------------    --------------
Net loss per
  Share of
  Common stock-
  Basic and diluted        $     (0.16)    $     (0.18)     $     (0.72)     $      (0.86)
                          -------------   ------------     -------------    --------------
</TABLE>

                                       9

<PAGE>


6.   PROPOSED MERGER

On December 10, 1998, the Company entered into an Agreement and Plan of 
Merger ("Merger Agreement") with Procept, Inc. ("Procept"), a 
biopharmaceutical company engaged in the development of novel drugs for the 
prevention of infectious diseases. The Merger Agreement provides that each of 
the Company's shares of common stock (including preferred stock on an as 
converted basis into common stock) will convert into 0.11 shares of Procept 
common stock or a total of 2,755,000 Procept shares (of which 1,151,048 
shares of Procept common stock to be issued in the merger to the holders of 
the Company's preferred stock shall be accompanied by certain contractual 
rights identical to contractual rights held by purchasers in Procept's 1998 
private placement, and as a result of such contractual rights, the holders of 
the Company's preferred stock will also receive 470,137 additional Procept 
shares). In addition, Procept has agreed to assume an approximately $7.3 
million obligation of the Company's subsidiary, BG Development Corp., and 
Procept has agreed to exchange all of the Company's outstanding warrant, unit 
purchase option and stock option obligations into like instruments of 
Procept. The merger remains contingent upon the final approval by both 
companies' shareholders. Both Companies' have scheduled Special Shareholders 
Meetings in mid-March 1999 to vote on the proposed merger. 

In conjunction with the Merger Agreement, the Company entered into a 
severence agreement with its former Chairman and President and recorded 
$325,000 liability under such agreement.
 
7.   SUBSEQUENT EVENTS

On February 4, 1999, the Company completed the merger with Binary 
Therapeutics, Inc. ("BTI"). The Company issued 2,158,268 shares of its common 
stock and assumed notes payable and accrued interest totaling $727,000. The 
Company also assumed a common stock warrant obligation and an obligation to 
issue shares of its common stock to a licensor in the event certain 
regulatory milestones are achieved. The transaction will be accounted for as 
a purchase.


                                       10

<PAGE>



                   PACIFIC PHARMACEUTICALS, INC. AND SUBSIDIARIES
                          (A DEVELOPMENT STAGE ENTERPRISE)
                          INCORPORATED SEPTEMBER 23, 1983
                                          
                        MANAGEMENT'S DISCUSSION AND ANALYSIS
                  OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

RESULTS OF OPERATIONS

QUARTER ENDED DECEMBER 31, 1998 COMPARED TO DECEMBER 31, 1997

Total revenues aggregated $53,000 for the quarter ended December 31, 1998, a 
$75,000 decrease from revenues of $128,000 recorded during the same period of 
the prior year. Current year revenues relate primarily to interest income 
generated on the Company's cash balances. Revenues for the same period in the 
prior year consisted of $59,000 in interest income and $69,000 in sales of 
the Company's Periodontal Tissue Monitor kit ("PTM").
 
Cost of product sales in the current quarter were $13,000 or a $74,000 
decrease from the same quarter in the prior year. The current year cost of 
product sales are fixed costs which relate to the PTM product, even though 
the Company had no sales of the PTM product in the current quarter. During 
the same quarter of the prior year, the Company sold approximately 1,000 PTM 
kits and incurred manufacturing and quality assurances costs associated with 
the PTM product. As described in Note 3, during the quarter ended December 
31, 1998, the Company determined it would no longer continue to sell the PTM 
product.

Product development costs totaled $332,000 for the current quarter, a 
decrease of $79,000 or 19% over the prior year second quarter costs of 
$411,000.  The decrease relates to the following areas:  (i) decrease of 
$110,000 in funding of product development expenses in accordance with the 
Agreement and Plan of Merger with Binary Therapeutics, Inc. ("BTI"), the 
holder of certain technologies in the area of Photodynamic Therapy ("PDT") 
for the treatment of cancer; (ii) a decrease of $52,000 in expenses related 
to Cancer Immunotherapy technology; (iii) a decrease of $21,000 in expenses 
related PTM product development; (iv) an increase of $96,000 in expenses 
related to the development of the Company's O(6) Benzylguanine ("BG") 
technology acquired in March 1998 and (v) a decrease of $1,000 in general 
product development expenses. 

General and administrative expenses for the current quarter were $813,000, an 
increase of $338,000 from the same period of the prior year. During the 
current year quarter, the Company signed a Merger Agreement with Procept and 
recorded $325,000 for a severence agreement with its former Chairman and 
President. Also during the quarter, the Company incurred significant legal 
and accounting fees in connection with the Merger Agreement. There were no 
such expenses incurred during the same quarter of the prior year. 

During the quarter ended December 31, 1998, the Company determined that it 
would no longer continue to sell it's PTM product. In that connection, the 
Company recorded as an other expense,  $113,000 to write-off inventory and 
unamortized patent costs. There were no such other expenses incurred during 
the same quarter of the prior year.  


                                       11

<PAGE>


Net loss for the quarter ended December 31, 1998 totaled $1,149,000 or a 30% 
increase over the prior year's third quarter loss of $883,000. This increase 
is primarily the  result of greater general and administrative and other 
expenses described above. Basic and diluted net loss per share of common 
stock for the quarter ended December 31, 1998 was $.09 compared to $.18 in 
the same quarter in the previous year. During the quarter ended December 31, 
1997, the Company recognized a non-cash convertible preferred stock dividend 
of $932,000, as restated. No such dividend was recognized during the current 
year quarter.

NINE MONTHS ENDED DECEMBER 31, 1998 COMPARED TO DECEMBER 31, 1997

Total revenues were $156,000 for the nine months ended December 31, 1998, a 
$137,000 decrease from revenues of $295,000 recorded during the same period 
of the prior year. Current revenues relate primarily to interest income 
generated on the Company's cash balances. Revenues for the same period in the 
prior year consisted of $225,000 in interest income and $70,000 in sales of  
PTM kits.
 
Cost of product sales was $41,000, relating to quality assurance and patent 
amortization expenses on the Company's PTM product. During the same period of 
the prior year, the Company sold approximately 1,000 PTM kits and incurred 
manufacturing and quality assurances costs associated with the PTM product. 
As described in Note 3, during the quarter ended December 31, 1998, the 
Company determined it would no longer continue to sell the PTM product.

The Company continued work on its first human clinical trial for its PDT 
cancer treatment, Boronated Porphyrin (BOPP). The Company also continued the 
development of the BG compound. Product development costs for the nine months 
ended December 31, 1998 decreased by $121,000 or 8% to $1,312,000 compared to 
the same period of the prior year. The decrease related to the following 
areas: (i) a decrease of $525,000 in funding of product development expenses 
for BOPP; (ii) an increase of $633,000 on expenses for the acquisition and 
development of BG (iii) $103,000 decrease in expenses related to Cancer 
Immunotherapy technology; (iv) a decrease of $120,000 in expenses related to 
PTM product development. 

General and administrative expenses for the nine months ended December 31, 
1998 were $1,590,000, a decrease of $82,000 from the same period of the prior 
year. In December 1998, the Company signed a Merger Agreement with Procept 
and recorded $325,000 for a severence agreement with its former Chairman and 
President. Also during the nine months period of the current year, the 
Company incurred significant legal and accounting fees in connection with the 
Merger Agreement.

Business development costs for the nine month period of the current year 
totaled $27,000, a decrease of $132,000, from the same period of the prior 
year. Expenses decreased as the Company spent less time and resources in 
developing corporate partnerships for its various products compared to the 
prior year. 

During the quarter ended December 31, 1998, the Company determined that it 
would no longer continue to sell it's PTM product. In that connection, the 
Company recorded as an other expense,  $113,000 to write-off inventory and 
unamortized patent costs. There were no such other expenses incurred during 
the same period of the prior year.  


                                       12

<PAGE>


Net loss for the nine months ended December 31, 1998 totaled $2,787,000 or a 
13% decrease over the prior year loss of $3,149,000. This decrease is 
primarily the result of lower general and administrative and product 
development expenses described above. Basic and diluted net loss per share of 
common stock for the nine months ended December 31, 1998 was $.52 compared to 
$.84 in the same period in the previous year. During the nine months ended 
December 31, 1998, the Company recognized a non-cash convertible preferred 
stock dividend of $3,294,000 compared to $4,360,000 (as restated) during the 
same period in the prior year.

CAPITAL RESOURCES AND LIQUIDITY

As described in Note 6 to the Consolidated Financial Statements, the Company 
has entered into a Merger Agreement with Procept, Inc. The merger is subject 
to approval by both companies' shareholders. 

Cash and cash equivalents at December 31, 1998 totaled $3,562,000, an 
increase of $271,000 from the March 31, 1998 balance. Working capital at 
December 31, 1998 decreased by $43,000 from March 31, 1998 to $2,504,000. 
These increases were primarily due to the closing on net proceeds of 
$2,455,000 of a private placement financing for the Company's majority owned 
subsidiary, BG Development Corp. ("BGDC"), offset by the net loss before 
convertible preferred stock dividends for the nine months ending December 31, 
1998. Seventy five percent of the net proceeds of the BGDC private placement 
will be used by BGDC for development costs associated with BG and 25% will go 
to the Company to be used for general purposes. In order to conserve cash, 
the Company has instituted a plan to reduce its cash burn rate.  

Since inception, the Company has experienced negative cash flow from 
operations, and the Company considers it prudent to anticipate that negative 
cash flow from operations will continue for the foreseeable future, and that 
outside sources of funding will continue to be required.  Without significant 
future revenues, the Company's financial resources are anticipated to be 
adequate through June 1999, based on a continuation of the pattern of 
expenses which have prevailed during fiscal years 1998 and 1997.

In March 1998, the Company signed a license agreement for the drug compound 
O(6) Benzylguanine ("BG") with the owners of the patents: Pennsylvania State
University, the National Institutes of Health (NIH), the University of 
Chicago, and Case Western Reserve University, (collectively, the 
"Co-Owners"), and in turn, assigned it to its subsidiary BGDC. 

The Company entered into a Cooperative Research and Development Agreement 
("CRADA") with the NIH to fund studies and clinical trials. Under the terms 
of the CRADA, the Company is obligated to provide funding of $125,000 per 
year for five years for joint research. The Company is also obligated to make 
additional milestone, royalty and patent reimbursement payments to the 
Co-Owners during the term of the License Agreement. The agreement also has a 
provision in which the Company may make certain portions of the 
aforementioned payments in common stock of the Company.   

In connection with the license agreement for BG, the Company entered into an 
introduction agreement with Paramount Capital Investments LLC ("PCI"). The 
Company paid PCI a commission of $100,000 plus 100,000 shares of the 
Company's common stock valued at $75,000 and reimbursed PCI $100,000 for its 
expenses in connection with the acquisition of the BG technology. The Company 
is also obligated to make milestone payments to PCI in the


                                       13

<PAGE>


Company's common stock of up to 900,000 shares if the BG compound 
successfully reaches certain milestones. The Company recorded $96,000 in 
product development expenses during the third quarter of FY 1999 and $933,000 
since inception of the program to develop the BG technology.

In June 1996 the Company entered into an agreement which granted the Company 
the option to acquire Binary Therapeutics, Inc. ("BTI"). Under the agreement 
as amended, the Company recorded expenses of $195,000 during the third 
quarter of FY 1999 and $3,426,000 since inception of the agreement, the 
Company  is currently funding substantially all expenses of BTI. As described 
in Note 7, the Company completed the merger of BTI into a wholly owned 
subsidiary of the Company in February 1999.

The Company has an agreement with Wound Healing of Oklahoma ("WHO") under 
which it acquired an exclusive license to certain proprietary technology for 
Cancer Immunotherapy. The Company incurred $19,000 during the third quarter 
of FY 1999 and $738,000 in product development expenses since the acquisition 
of the license and expects to continue funding such efforts associated with 
the commercialization of the licensed technology, including the commencement 
of human clinical trials, which will increase the Company's net utilization 
of cash.  However, there can be no assurance that FDA and other regulatory 
approval required to commence such trials will be forthcoming.

In September 1998, the Company's common stock was removed from trading on the 
American Stock Exchange ("AMEX") because the Company no longer satisfies all 
of the financial guidelines of the AMEX for continued listing. The Company's 
common stock began trading on the NASD Electronic Bulletin Board under the 
ticker symbol PHAA.

YEAR 2000 COMPLIANCE.  The Company recognizes the need to ensure its 
operations will not be adversely impacted by the inability of the Company's 
systems to process data having dates on or after January 1, 2000 ("Year 
2000"). Processing errors due to software failure arising from calculations 
using the Year 2000 date are recognized as a risk. The Company is currently 
assessing the risk, with respect to the availability and integrity of its 
financial systems and the reliability of its operating systems, and is in the 
process of communicating with suppliers, customers, financial institutions 
and others with whom it conducts business to assess whether they are or will 
be Year 2000 compliant.

The Company's information technology systems consist of a series of personal 
computers which  process data using purchased software programs produced and 
maintained by large software vendors. All of the software presently installed 
on the Company's systems is Year 2000 compliant.

The Company has contacted all of its vendors to determine each vendors' 
compliance with Year 2000 issues. As of December 31, 1998, 80% of all of the 
Company's vendors have responded that they are now Year 2000 compliant. The 
Company is continuing to determine the Year 2000 compliance status of the 
remaining vendors. The Company hopes to have responses from all vendors and 
institutions with whom it does business by March 31, 1999. The Company's 
critical suppliers and financial institutions are large organizations and the 
Company believes all are now or will be Year 2000 compliant by December 31, 
1999.   


                                       14

<PAGE>


The Company believes its exposure to any material Year 2000 problems is 
relatively small because its financial and operating systems have been 
produced and maintained by large software vendors which are Year 2000 
compliant and the Company relies on very large Year 2000 compliant vendors 
for its critical services. However,  there can be no assurance that the 
Company's systems or systems of other companies on which the Company's 
operations rely will be converted on a timely basis and will not have a 
material effect on the Company. 

The cost of the Company's Year 2000 initiatives has not been or is not 
expected to be material to the Company's results of operations or financial 
position.

PART II-OTHER INFORMATION

ITEM 5.  OTHER INFORMATION

On December 10, 1998, the Company entered into an Agreement and Plan of 
Merger ("Merger Agreement") with Procept, Inc. ("Procept"), a 
biopharmaceutical company engaged in the development of novel drugs for the 
prevention of infectious diseases. The Merger Agreement provides that each of 
the Company's shares of common stock (including preferred stock on an as 
converted basis into common stock) will convert into approximately 0.11 
shares of Procept common stock or a total of 2,755,000 Procept shares (of 
which 1,151,048 shares of Procept common stock to be issued in the merger to 
the holders of the Company's preferred stock shall be accompanied by certain 
contractual rights identical to contractual rights held by purchasers in 
Procept's 1998 private placement, and as a result of such contractual rights, 
the holders of the Company's preferred stock will also receive 470,137 
additional Procept shares). In addition, Procept has agreed to assume an 
approximately $7.3 million obligation of the Company's subsidiary, BG 
Development Corp., and Procept has agreed to exchange all of the Company's 
outstanding warrant, unit purchase option and stock option obligations into 
like instruments of Procept. The merger remains contingent upon the approval 
by both companies' shareholders.

On February 4, 1999, the Company completed the merger with BTI. The Company 
issued 2,158,268 shares of its common stock and assumed notes payable and 
accrued interest totaling $727,000. The Company also assumed a common stock 
warrant obligation and an obligation to issue shares of its common stock to a 
licensor in the event certain regulatory milestones are achieved. 

ITEM 6.  EXHIBITS AND REPORTS ON FORM 8-K

     EXHIBITS


  Exhibit
  Number            Description of Exhibit
- ------------        ----------------------
   10.44        Agreement and Plan of Merger Between Procept, Inc., Procept
                Acquisition Corp. and Pacific Pharmaceuticals, Inc., dated
                December 10, 1998
   10.45        Amendment to Agreement and Plan of Merger


     REPORTS ON FORM 8-K

          None



                                       15

<PAGE>


Pursuant to the requirements of the Securities Exchange Act of 1934, the 
registrant has duly caused this report to be signed on its behalf by the 
undersigned thereunto duly authorized.

                                   Pacific Pharmaceuticals, Inc.



Date:  February 12, 1999            /s/  James Hertzog
                                    ------------------
                                    James Hertzog
                                    Controller     
                                    (Principal Accounting Officer and 
                                    duly authorized to sign this report on 
                                    behalf of the registrant)



                                       16




<PAGE>

                                                                EXHIBIT 10.44




                            AGREEMENT AND PLAN OF MERGER
                                          
                                      BETWEEN
                                          
                                   PROCEPT, INC.
                                          
                             PROCEPT ACQUISITION CORP.
                                          
                                        AND
                                          
                           PACIFIC PHARMACEUTICALS, INC.
                                          
                           _____________________________
                                          
                           Dated as of December 10, 1998
                                          
                           _____________________________

<PAGE>


                                                               EXHIBIT 10.44

                            AGREEMENT AND PLAN OF MERGER


       THIS AGREEMENT AND PLAN OF MERGER dated as of December 10, 1998 (this 
"Agreement") is among Procept, Inc. ("Procept"), a Delaware corporation, 
Procept Acquisition Corp. ("PAC"), a Delaware corporation, and Pacific 
Pharmaceuticals, Inc. ("Pacific"), a Delaware corporation.  The parties wish 
to effect the acquisition of Pacific by Procept through a merger of PAC into 
Pacific on the terms and conditions hereof.  This Agreement is intended to be 
a "plan of reorganization" within the meaning of Section 368(a) of the 
Internal Revenue Code of 1986, as amended (the "Code").

       Accordingly, in consideration of the mutual representations, 
warranties and covenants contained herein, the parties hereto agree as 
follows:

                                SECTION 1 - THE MERGER

       1.1    THE MERGER.  Upon the terms and subject to the conditions 
hereof, and in accordance with the General Corporation Law of the State of 
Delaware (the "DGCL"), PAC shall be merged with and into Pacific (the 
"Merger").  The Merger shall occur at the Effective Time (as defined herein). 
 Following the Merger, Pacific shall continue as the surviving corporation 
(the "Surviving Corporation") and the separate corporate existence of PAC 
shall cease.

       1.2    EFFECTIVE TIME.  As soon as practicable after satisfaction or 
waiver of all conditions to the Merger, the parties shall cause a Certificate 
of Merger to be filed in accordance with Section 252 of the DGCL (the "Merger 
Certificate") and shall take all such further actions as may be required by 
law to make the Merger effective.  The Merger shall be effective at such time 
as the Merger Certificate is filed, as appropriate, with the Secretary of 
State with the State of Delaware in accordance with the DGCL or at such later 
time as is specified in such documents (the "Effective Time").  Immediately 
prior to the filing of the Merger Certificate, a closing (the "Closing") will 
be held at the offices of Palmer & Dodge LLP, One Beacon Street, Boston, 
Massachusetts (or such other place as the parties may agree) for the purpose 
of confirming satisfaction or waiver of all conditions to the Merger.  
Subject to satisfaction or waiver of each of the conditions specified in 
Sections 5, 6 and 7 hereof, the Closing shall take place within three 
business days after the last to occur of:

              (a)    the day the Merger is approved by the stockholders of 
Pacific pursuant to Section 5.11; or 

              (b)    the day the issuance of the Merger Consideration (as 
defined below) is approved by the stockholders of Procept pursuant to Section 
5.12;

or on such other date as the parties may agree, but not later than June 30, 
1999.  The date on which the Closing occurs is referred to herein as the 
"Closing Date".

       1.3    EFFECTS OF THE MERGER.  The Merger shall have the effects set 
forth in Section 259, 260 and 261 of the DGCL.

                                       2
<PAGE>

       1.4    CERTIFICATE OF INCORPORATION AND BYLAWS.  The Certificate of 
Incorporation and Bylaws of Pacific, in each case as in effect immediately 
prior to the Effective Time shall be the Certificate of Incorporation and 
Bylaws of the Surviving Corporation immediately after the Effective Time, 
until duly amended in accordance with applicable law.

       1.5    DIRECTORS AND OFFICERS.  The directors and officers of PAC 
immediately prior to the Effective Time shall be the directors and officers 
of the Surviving Corporation immediately after the Effective Time, each such 
officer and director to hold office in accordance with their respective 
terms. 

       1.6    CONVERSION OF STOCK.

              (a)    For purposes of this Agreement, "Merger Consideration" 
means 2,755,000 shares of common stock, $0.01 par value per share, of Procept 
("Procept Common Stock") reduced by the number of shares of Procept Common 
Stock which would be issued but for the terms of Section 262 of the DGCL in 
respect of Dissenting Shares (as defined in Section 1.8).

              (b)    At the Effective Time, by virtue of the Merger and 
without any action on the part of Procept or Pacific:

                            (i)    All shares of Common Stock of Pacific, 
$0.02 par value per share (the "Pacific Common Stock") and all shares of 
Preferred Stock of Pacific, $25 par value per share, (the "Pacific Preferred 
Stock" collectively, with the Pacific Common Stock the "Pacific Stock") 
outstanding immediately prior to the Effective Time, other than Dissenting 
Shares (as defined in Section 1.8), shall be converted into and become the 
right to receive, (subject to the payment of cash for fractional shares as 
provided in Section 1.10) shares of Procept Common Stock in accordance with 
Section 1.6(c).

                            (ii)   All options and warrants to purchase 
Pacific Stock outstanding immediately prior to the Effective Time, shall be 
exercisable for that number of shares of Procept Common Stock which such 
option or warrant holder would have been entitled to receive if the 
underlying Pacific Stock had converted in the Merger, at an exercise price 
per share equal to the aggregate exercise price of the Pacific option or 
warrant exchanged divided by the number of shares of Procept Common Stock 
subject to the new option or warrant, and otherwise having the same terms and 
conditions as the Pacific option or warrant and otherwise in accordance with 
the terms of Section 5.19.

                            (iii)  All shares of Pacific Stock held at the 
Effective Time by Pacific as treasury stock or by a subsidiary of Pacific 
shall be canceled and no payment shall be made with respect thereto.

                            (iv)   All Dissenting Shares shall be dealt with 
in accordance with Section 1.8.

                            (v)    All shares of Common Stock of PAC, $0.01 
par value per share, outstanding immediately prior to the Effective Time, 
shall be converted into the right to receive the same number of shares of the 
Surviving Corporation.

                                       3
<PAGE>

              (c)    The Merger Consideration shall be allocated among the 
holders of shares of Pacific Stock outstanding immediately prior to the 
Effective Time by allocating to each such holder of Pacific Stock outstanding 
at the Effective Time (other than the holders of Dissenting Shares) that 
number of shares of Procept Common Stock determined by multiplying the number 
of shares of Pacific Common Stock held by each such holder or issuable to a 
holder on conversion of Pacific Preferred Stock held by such holder by the 
Conversion Factor (as defined below).

              (d)    "Conversion Factor" means the quotient obtained by 
dividing (i) 2,755,000 BY (ii) the number of shares of Pacific Common Stock 
either outstanding or issuable on conversion of outstanding shares of Pacific 
Preferred Stock immediately prior to the Effective Time.  As of the date of 
this Agreement, based on the shares of Pacific Common Stock currently 
outstanding or issuable (i) on conversion of outstanding Pacific Preferred 
Stock and (ii) upon the closing of the Agreement and Plan of Merger between 
Pacific and Binary Therapeutics, Inc., the Conversion Factor is 0.11.  

              (e)    The Merger Consideration shall be adjusted in the event 
of any change in Procept Common Stock by reason of a stock splits, stock 
recapitalizations, combinations or subdivisions of the Common Stock of 
Procept, mergers or other exchanges of shares by operation of law or the like 
occurring after the date of this Agreement and before the Effective Time, 
such that, after the record date therefor the Merger Consideration shall be 
equal to the number and class of shares or other securities or property that 
would have been received in respect of a share of Procept Common Stock, as 
the case may be, if the Effective Time had occurred immediately prior to such 
record date.

       1.7    CLOSING OF PACIFIC TRANSFER BOOKS.  At the Effective Time, the 
stock transfer books of Pacific shall be closed and no transfer of Pacific 
Stock shall thereafter be made.  If, after the Effective Time, certificates 
representing shares of Pacific Stock are presented to the Exchange Agent, 
they shall be canceled and exchanged for certificates representing Procept 
Common Stock.

       1.8    PACIFIC DISSENTING SHARES.

              (a)    Shares of Pacific Stock held by a stockholder who has 
properly exercised appraisal rights with respect thereto in accordance with 
Section 262 of the DGCL are referred to herein as "Dissenting Shares".  
Shares of Pacific Stock that constitute Dissenting Shares shall not be 
converted into Merger Consideration and shares of Procept Stock shall not be 
issued pursuant to Section 1.6(d) in exchange therefor.  From and after the 
Effective Time, a stockholder who has properly exercised such appraisal 
rights shall no longer retain any rights of a stockholder of Pacific or the 
Surviving Corporation, except those provided under the DGCL.

              (b)    Pacific shall give Procept (i) prompt notice of any 
written notices and demands under Section 262 of the DGCL with respect to any 
shares of capital stock of Pacific, any withdrawal of any such demands and 
any other instruments served pursuant to the DGCL and received by Pacific and 
(ii) the right to participate in all negotiations and proceedings with 
respect to any demands under Section 262 with respect to any shares of 
capital stock of Pacific.  Pacific shall cooperate with Procept concerning, 
and shall not, except with the prior written 

                                       4
<PAGE>

consent of Procept, voluntarily make any payment with respect to, or offer to 
settle or settle, any such demands.

              (c)    In the event that a holder of Pacific Stock makes a 
demand under Section 262 of the DGCL the Merger Consideration shall be 
reduced by the number of shares of Procept Common Stock which would otherwise 
have been issued to such holder.

       1.9    ISSUANCE OF PROCEPT CERTIFICATES.  Prior to the Effective Time, 
Procept shall authorize one or more persons to act as Exchange Agent 
hereunder (the "Exchange Agent") and shall deposit with or for the account of 
the Exchange Agent certificates representing the number of shares or Procept 
Common Stock equaling the Merger Consideration and cash in lieu of fractional 
shares of Procept Common Stock.  As soon as practicable after the Effective 
Time, (i) Pacific shall deliver to Procept a list of all record holders of 
Pacific Stock immediately prior to the Effective Time (the "Record Holders"), 
setting forth each stockholder's name, address and number of shares of 
Pacific Stock held prior to the Effective Time and such other information as 
may be reasonably requested by the Exchange Agent, certified by the Chief 
Executive Officer of Pacific (the "Stockholder List") and (ii) the Exchange 
Agent shall be instructed to mail to each Record Holder a form of letter of 
transmittal which shall specify instructions for use in effecting the 
surrender of Pacific Stock certificates in exchange for Merger Consideration. 
 Upon the Exchange Agent's receipt of the letter of transmittal and any 
certificate held by a stockholder, each stockholder shall be entitled to 
receive a certificate representing that number of whole shares of Procept 
Common Stock into which the shares of Pacific Stock as set forth on the 
Stockholder List shall have been converted pursuant to the provisions of this 
Agreement.  The shares of Pacific Stock outstanding immediately prior to the 
Effective Time (and any certificates representing such shares) shall be 
deemed canceled as of the Effective Time.  Procept Common Stock into which 
Pacific Stock shall be converted in the Merger shall be deemed to have been 
issued at the Effective Time.  If any Procept Common Stock certificates are 
to be issued in a name other than that in which the Pacific Stock was 
registered immediately prior to the Effective Time, it shall be a condition 
of such issuance that the person requesting such issuance shall deliver to 
the Exchange Agent all documents necessary to evidence and effect such 
transfer and shall pay to the Exchange Agent any transfer or other taxes 
required by reason of the issuance of certificates for such shares of Procept 
Common Stock in a name other than that of the registered holder of the 
certificate or surrendered or establish to the satisfaction of the Exchange 
Agent that such tax has been paid or is not applicable. None of Procept, PAC 
or Pacific shall be liable to any stockholder for shares of stock or any cash 
in lieu of fractional interests delivered to a public official pursuant to 
applicable escheat or abandoned property laws.

       1.10   NO FRACTIONAL SHARES.  No certificates representing fractional 
shares of Procept Common Stock shall be issued upon the surrender for 
exchange of Pacific Stock certificates.  No fractional interest shall entitle 
the owner to vote or to any rights of a security holder.  In lieu of 
fractional shares, each stockholder who would otherwise have been entitled to 
a fractional share of Procept Common Stock, will receive from Procept at 
Closing an amount in cash (without interest) determined by multiplying such 
fraction by the fair market value of a share of Procept Common Stock.  Such 
fair market value shall equal the mean of the daily high and low sales prices 
of the Procept Common Stock on the Nasdaq Small Cap Market, as reported by 
Nasdaq, averaged over the period of ten (10) trading days ending on the fifth 
trading day prior to the Closing Date.

                                       5
<PAGE>

               SECTION 2 - REPRESENTATIONS AND WARRANTIES OF PAC

       Procept and PAC hereby make the following representations and warranties:

       2.1    ORGANIZATION AND CORPORATE POWER.  PAC is a corporation duly 
incorporated, validly existing and in good standing under the laws of 
Delaware.

       2.2    CORPORATE AUTHORIZATION.  PAC has all requisite corporate power 
and authority to enter into this Agreement and to consummate the transactions 
contemplated hereby.  The execution, delivery and performance by the PAC of 
this Agreement and the consummation by PAC of the transactions contemplated 
hereby have been duly authorized by all necessary corporate action on the 
part of PAC, enforceable against it in accordance with its terms.

       2.3    NON-CONTRAVENTION.  The execution, delivery and performance by 
PAC of this Agreement and the consummation by PAC of the transactions 
contemplated hereby do not and will not contravene or conflict with the 
Certificate of Incorporation or By-Laws of PAC.

       2.4    NO BUSINESS ACTIVITIES.  PAC has not conducted any business 
activities unrelated to the transactions contemplated hereby.

                SECTION 3 - REPRESENTATIONS AND WARRANTIES OF PACIFIC

       Except as set forth on the disclosure schedule (the "PACIFIC 
DISCLOSURE SCHEDULE") delivered to Procept on the date hereof, (regardless of 
whether the PACIFIC DISCLOSURE SCHEDULE is referenced in any particular 
subsection of this Section 3), the subsection numbers of which are numbered 
to correspond to the subsection numbers of this Agreement to which they refer 
(provided that disclosure thereon under any subsection number shall be 
disclosure for any section hereof), Pacific represents and warrants to 
Procept as set forth below:

       3.1    ORGANIZATION AND QUALIFICATION. Pacific and each of its 
subsidiaries named on the Pacific Disclosure Schedule pursuant to Section 3.4 
below (the "Subsidiaries") is a corporation duly organized, validly existing 
and in good standing under the laws of the state or other jurisdiction of its 
incorporation and has full corporate power and authority to own, lease and 
operate its assets, properties and business and to carry on its business as 
now being and as heretofore conducted.  Pacific is qualified or is otherwise 
authorized to transact business as a foreign corporation in each jurisdiction 
(in the United States and outside of the United States) in which the failure 
to so qualify would have a material adverse effect on the business or 
financial condition of Pacific or its subsidiaries (other than changes that 
are the effect of economic factors affecting the economy or the 
pharmaceutical industry as a whole) (a "Pacific Material Adverse Effect"), 
all of which jurisdictions are identified in Section 3.1 of the PACIFIC 
DISCLOSURE SCHEDULE.

       3.2    CAPITALIZATION.

              3.2.1  OUTSTANDING CAPITAL STOCK.  Pacific's authorized capital 
stock consists of 100,000,000 shares of Common Stock, $0.02 par value per 
share, of which 12,280,017 shares are issued and outstanding as of November 
17, 1998, and 2,000,000 shares of Preferred Stock, $25 par value per share, 
of which 36,696 shares are issued and outstanding as of November, 1998

                                       6

<PAGE>

and convertible into 10,674,499 shares of Pacific Common Stock.  Except as 
disclosed in Pacific's proxy statement for its annual meeting of stockholders 
held on August 13, 1998, Pacific is not aware of any record or beneficial 
holder of more than five percent (5%) of the outstanding shares of Pacific 
Stock.  The outstanding shares of Pacific Stock are duly authorized, validly 
issued, fully paid, and nonassessable and have been issued in compliance with 
all charter documents of Pacific and all applicable federal and state laws. 
Except as set forth in this Section 3.2.1, no other capital stock of Pacific 
is authorized or outstanding.

              3.2.2  OPTIONS OR OTHER RIGHTS.  Except as set forth in the 
PACIFIC DISCLOSURE SCHEDULE, (i) no subscription, warrant, option, preemptive 
right, convertible security or other right (contingent or otherwise) to 
purchase or acquire any shares of capital stock or other security of Pacific 
issued by Pacific is authorized or outstanding, (ii) there is no commitment 
or offer by Pacific to issue or provide any such subscription, warrant, 
option, preemptive right, convertible security or other right or to issue or 
distribute to holders of any shares of its capital stock any evidences of 
indebtedness or assets of Pacific, (iii) Pacific has no obligation 
(contingent or otherwise) to purchase, redeem or otherwise acquire any shares 
of its capital stock or any interest therein or to pay any dividend or make 
any other distribution in respect thereof, (iv) there are no restrictions on 
the transfer of Pacific's capital stock other than those arising from 
securities laws, and (v) there are no voting trusts, proxies or other 
agreements, instruments or understandings with respect to outstanding shares 
of Pacific's capital stock to which Pacific is a party. 

       3.3    AUTHORITY TO EXECUTE AND PERFORM AGREEMENTS.  Subject to the 
requirement to obtain approval of its stockholders to consummate the Merger 
under the DGCL, Pacific has the requisite corporate power and authority to 
execute and deliver this Agreement and each agreement, document and 
instrument contemplated by this Agreement to which it is a party, to 
consummate the transactions contemplated hereby and thereby and to perform 
fully its respective obligations hereunder and thereunder.  The execution, 
delivery and performance of this Agreement and each such other agreement, 
document and instrument to which it is a party and the consummation of the 
transactions contemplated hereby and thereby have been duly authorized by all 
necessary corporate action on the part of Pacific.  This Agreement and each 
agreement, document and instrument to which it is a party executed and 
delivered pursuant to this Agreement constitutes, or when executed and 
delivered will constitute, valid and binding obligations of Pacific, 
enforceable in accordance with their terms.

       3.4    SUBSIDIARIES AND OTHER AFFILIATES. Except as set forth in the 
PACIFIC DISCLOSURE SCHEDULE, Pacific does not have any subsidiary or directly 
or indirectly own or have any investment in any of the capital stock of, or 
any other interest in, any other person or entity.  The PACIFIC DISCLOSURE 
SCHEDULE indicates the number of shares of capital stock of each Subsidiary 
held by Pacific and the total shares of capital stock outstanding for each 
Subsidiary. The PACIFIC DISCLOSURE SCHEDULE also indicates whether any 
warrant, option or other right to acquire an equity interest in any 
Subsidiary is outstanding.  For the purposes of the representations and 
warranties in this Section 3 and the covenants set forth in Section 5, Binary 
Therapeutics, Inc. shall be deemed to be a Subsidiary, unless the language of 
any particular provision clearly indicates a contrary intent.

       3.5    CHARTER AND BY-LAWS; BOOKS AND RECORDS. Pacific has heretofore
delivered or made available to Procept true and complete copies of the
Certificate of Incorporation (certified 

                                       7

<PAGE>

by the Secretary of State or comparable authority of its jurisdiction of 
incorporation) and By-laws as in effect on the date hereof for itself and 
each of its Subsidiary, and corporate minute books. None of Pacific or any 
Subsidiary is in default in the performance, observation or fulfillment of 
either its charter or By-laws.  The minute books of Pacific and each 
Subsidiary contain true and complete records of all meetings and consents in 
lieu of meetings of the Board of Directors and of the stockholders prior to 
the date hereof, and accurately reflect all transactions referred to in such 
minutes and consents in lieu of meetings.

       3.6    SEC REPORTS.  Pacific has previously delivered to Procept its 
(i) Annual Report on Form 10-K for the year ended March 31, 1998 (the 
"Pacific 10-K"), as filed with the Securities and Exchange Commission (the 
"SEC"), (ii) the proxy statement relating to Pacific's annual meeting of 
stockholders held on August 13, 1998 and (iii) all other reports filed by 
Pacific with the SEC under the Securities Exchange Act of 1934, as amended 
(the "Exchange Act"), since January 1, 1998.  As of their respective dates, 
such reports complied in all material respects with applicable SEC 
requirements and did not contain any untrue statement of a material fact or 
omit to state a material fact required to be stated therein or necessary to 
make the statements therein, in light of the circumstances under which they 
were made, not misleading.  Pacific has timely filed with the SEC all reports 
required to be filed under Sections 13, 14 or 15(d) of the Exchange Act since 
becoming registered under the Exchange Act.

       3.7    FINANCIAL STATEMENTS.  The consolidated financial statements 
contained in the Pacific 10-K and in Pacific's quarterly report on Form 10-Q 
for the quarter ended September 30, 1998 (the "PACIFIC 10-Q") have been 
prepared from, and are in accordance with, the books and records of Pacific 
and each Subsidiary (required to be so consolidated) and fairly present the 
consolidated financial condition, results of operations and cash flows of 
Pacific as of the dates and for the periods presented therein, all in 
accordance with generally accepted accounting principles applied on a 
consistent basis, except as otherwise indicated therein and subject (in the 
case of the unaudited financial statements included in the Pacific 10-Q) to 
normal year-end and audit adjustments and footnote disclosures, which in the 
aggregate are not material.

       3.8    ABSENCE OF UNDISCLOSED LIABILITIES.  Except as set forth in the 
PACIFIC DISCLOSURE SCHEDULE at March 31, 1998, Pacific and its Subsidiaries 
have no material liabilities of any nature, whether accrued, absolute, 
contingent or otherwise (including without limitation, liabilities as 
guarantor or otherwise with respect to obligations of others or liabilities 
for taxes due or then accrued or to become due), required to be reflected or 
disclosed in the balance sheet dated March 31, 1998 (or the notes thereto) 
included in the Pacific 10-K (the "PACIFIC BALANCE SHEET") that were not 
adequately reflected or reserved against on such balance sheet.  Except as 
set forth in the PACIFIC DISCLOSURE SCHEDULE, Pacific and its Subsidiaries 
have no such liabilities, except as and to the extent (i) adequately 
reflected and reserved against in the Pacific Balance Sheet, (ii) adequately 
reflected and reserved against in the Pacific unaudited balance sheet dated 
September 30, 1998 included in the Pacific 10-Q (the "PACIFIC INTERIM BALANCE 
SHEET"), or (iii) incurred since March 31, 1998 in the ordinary course of 
business and not material in amount, either individually or in the aggregate.

       3.9    NO MATERIAL ADVERSE CHANGE. Since March 31, 1998, there has not 
been:

                                       8
<PAGE>

                            (i)    any material adverse change in the assets, 
liabilities, condition (financial or otherwise), results of operation, 
business or prospects of Pacific or its Subsidiaries or any occurrence or 
circumstance which reasonably could be expected to result in such a material 
adverse change;

                            (ii)   any material change in the method of 
operating the business of Pacific or its Subsidiaries, in the manner of 
keeping the books, accounts or records of Pacific or its Subsidiaries, or in 
any accounting method or practice of Pacific or its Subsidiaries;

                            (iii)  any sale, lease, mortgage, pledge, 
encumber, abandonment or disposition of, or agreement to sell, lease, 
mortgage, pledge, encumber, abandon or dispose of, any material assets or 
properties of Pacific or its Subsidiaries, other than in the usual and 
ordinary course of business;

                            (iv)   any material transaction, commitment, 
contract or agreement entered into by Pacific or its Subsidiaries, or any 
relinquishment or abandonment by Pacific or its Subsidiaries of any material 
contract or right, or any modification, waiver, amendment, release, recision, 
or termination of any material term, condition or provision of any contract 
pertaining to Pacific or its Subsidiaries (other than any satisfaction by 
performance in accordance with the terms thereof), other than in the usual 
and ordinary course of business; 

                            (v)    any adverse relationships or conditions 
with employees, suppliers, lenders, customers or governmental agencies that 
could reasonably be anticipated to have a Pacific, or its Subsidiaries 
Material Adverse Effect on Pacific or its business;

                            (vi)   any acquisition by Pacific or its 
Subsidiaries (other than property or interests therein acquired in the 
ordinary course of its lending business) of all or any part of the assets, 
properties, capital stock or business of any other person or entity;

                            (vii)  any redemption or other acquisition by 
Pacific or its Subsidiaries of any of its capital stock or any declaration, 
setting aside or payment of any dividend or distribution of any kind with 
respect to shares of its capital stock;

                            (viii) any loan or advance by Pacific or its 
Subsidiaries to any stockholder, officers, director or consultant, or any 
other loan or advance other than in the ordinary course of business; or

                            (ix)   except as set forth in the PACIFIC 
DISCLOSURE SCHEDULE, any new employment or consulting agreement, any increase 
in compensation, bonus or other benefits payable or to become payable by 
Pacific or its Subsidiaries to any director, officer or employee, other than 
regularly scheduled increases consistent with past practice in the ordinary 
course of business, or any new grant of severance or termination rights, or 
increase in rights or benefits payable under existing severance or 
termination policies or agreements, to any director, officer or employee of 
Pacific.

       3.10   TAX MATTERS.  

                                       9

<PAGE>

              (a)    DEFINITION OF TAXES.  For the purposes of this 
Agreement, "Tax" or, collectively, "Taxes", means any and all federal, state, 
local and foreign taxes, assessments and other governmental charges, duties, 
impositions and liabilities in the nature of a tax including taxes based upon 
or measured by gross receipts, income, profits, sales, use and occupation, 
and value added, ad valorem, transfer, franchise, withholding, payroll, 
recapture, employment, excise and property taxes, together with all interest, 
penalties and additions imposed with respect to such amounts and any 
obligations under any agreements or arrangements with any other person with 
respect to such amounts and including any liability for taxes of a 
predecessor entity. 

              (b)    Tax Returns and Audits.  Except as set forth in the 
Pacific Disclosure Schedule:

                            (i)    Each of Pacific and its Subsidiaries has 
prepared and filed all required federal, state, local and foreign returns, 
estimates, information statements and reports ("Returns") required to be 
filed relating to any and all Taxes concerning or attributable to Pacific or 
such Subsidiary or its operations and such Returns are true and correct in 
all material respects and have been completed in all material respects in 
accordance with applicable law or, with respect to any Taxes payable, an 
adequate reserve has been established on the Pacific Interim Balance Sheet.

                            (ii)   Each of Pacific and its Subsidiaries: (A) 
has paid or accrued all Taxes set forth on its Returns, and (B) has withheld 
and paid (or will pay at the time required) with respect to its employees all 
federal and state income taxes, FICA, FUTA and other Taxes required to be 
withheld.

                            (iii)  Neither Pacific nor any of its 
Subsidiaries is delinquent in any material respect in the payment of any Tax 
nor is there any material Tax deficiency outstanding, proposed or assessed 
against Pacific or any of its Subsidiaries, nor has Pacific or any Subsidiary 
executed any waiver of any statute of limitations on or extending the period 
for the assessment or collection of any Tax.

                            (iv)   Other than the audits set forth in the 
PACIFIC DISCLOSURE SCHEDULE, no audit or other examination of any Return of 
Pacific is currently in progress, nor has Pacific or any Subsidiary been 
notified of any request for such an audit or other examination.

                            (v)    Pacific and its Subsidiaries did not have, 
as of September 30, 1998, any liabilities, whether asserted or unasserted, 
contingent or otherwise, for unpaid federal, state, local and foreign Taxes 
which have not been accrued or reserved against in accordance with GAAP on 
the Pacific Interim Balance Sheet, and neither Pacific nor any of its 
Subsidiaries has incurred any such liabilities since such date except in the 
ordinary course of business and consistent with past practices.

                            (vi)   There are (and as of immediately following 
the Effective Date there will be) no liens, pledges, charges, claims, 
security interests or other encumbrances of any sort ("Liens") of a material 
nature on the assets of Pacific or any Subsidiary relating to or attributable 
to Taxes, except for Liens for Taxes not yet due and payable or that are 
being contested in good faith by appropriate proceedings. 

                                       10

<PAGE>

                            (vii)  Neither Pacific nor any Subsidiary has 
received written or oral notice of any claim relating or attributable to 
Taxes that, if adversely determined, would result in any Lien on the assets 
of Pacific or any Subsidiary.

                            (viii) None of Pacific's or its Subsidiaries' 
assets are treated as "tax-exempt use property" within the meaning of Section 
168(h) of the Code.

                            (ix)   As of the Effective Time, there will not 
be any contract, agreement, plan or arrangement, including but not limited to 
the provisions of this Agreement, covering any employee or former employee of 
Pacific or any of its subsidiaries that, individually or collectively, could 
give rise to the payment of any amount that would not be deductible pursuant 
to Section 280G of the Code or the limitations in Sections 162 of the Code.

                            (x)    Neither Pacific nor any of its 
Subsidiaries has filed any consent agreement under Section 341(f) of the Code 
or agreed to have Section 341(f)(2) of the Code apply to any disposition of a 
subsection (f) asset (as defined in Section 341(f)(4) of the Code) owned by 
Pacific or such Subsidiary.

                            (xi)   Neither Pacific nor any of its 
Subsidiaries is a party to a tax sharing or allocation agreement nor does 
Pacific or any Subsidiary owe any amount under any such agreement.

                            (xii)  Neither Pacific nor any of its 
Subsidiaries is or has been at any time during the period specified in 
Section 897(c)(1)(A)(ii) of the Code, a "United States real property holding 
corporation" within the meaning of Section 897(c)(2) of the Code.

                            (xiii) Neither Pacific nor any Subsidiary has 
agreed to, or is required to, make any adjustments under Section 481(c) of 
the Code by reason of a change in accounting method or otherwise.

       3.11   COMPLIANCE WITH LAWS.

              3.11.1 None of Pacific or any Subsidiary is in violation in any 
material respect of any order, judgment, injunction, award or decree, or any 
federal, state, local or foreign law, ordinance or regulation or any other 
requirement of any governmental or regulatory body, court or arbitrator, and 
is in compliance in all material respects with all of the foregoing that are 
applicable to it, its business or its assets.  None of Pacific or any 
Subsidiary has received notice of, and there has not been any citation, fine 
or penalty imposed or asserted against any of them for, any such violation or 
alleged violation that has not been favorably and fully resolved.

              3.11.2 Each of Pacific and the Subsidiaries holds all licenses, 
permits, certificates, franchises, orders or approvals of any federal, state, 
local or foreign governmental or regulatory body, that are material to the 
conduct of such company's business and the uses of its assets (collectively, 
"PERMITS") necessary to operate its business as presently conducted.  The 
PACIFIC DISCLOSURE SCHEDULE contains a true and complete list of all such 
permits as of the date hereof.  Such Permits are in full force and effect and 
the validity and effectiveness of such 

                                       11

<PAGE>

Permits will not be affected by the transactions contemplated hereby.  No 
violations are or have been recorded with any governmental or regulatory body 
in respect of any Permit, no proceeding is pending or, to the best knowledge 
of Pacific, threatened to revoke or limit any Permit, and Pacific knows of no 
grounds for any such revocation or limitation.

       3.12   CONSENTS; NO BREACH. All consents, permits, authorizations and 
approvals from any person or entity that are required pursuant to applicable 
law, or agreement or otherwise in connection with the execution, delivery and 
performance of this Agreement by Pacific are set forth in Section 3.12 of the 
PACIFIC DISCLOSURE SCHEDULE, other than those which the failure to obtain 
would not affect the validity of this transaction or materially adversely 
affect the business of the Surviving Corporation after the Effective Time.  
Subject to any prior approval requirements set forth in Section 3.12 of the 
PACIFIC DISCLOSURE SCHEDULE, the execution, delivery and performance of this 
Agreement and the consummation of the transactions contemplated hereby will 
not (i) violate any provision of the Certificate of Incorporation or By-laws 
of Pacific or any Subsidiary; (ii) violate, conflict with or result in the 
breach of any of the terms or conditions of, result in a material 
modification of, or otherwise give any other contracting party the right to 
terminate, or constitute (or with notice or lapse of time or both constitute) 
a default under, any material instrument, contract or other agreement to 
which Pacific or any Subsidiary is a party or to which Pacific or any 
Subsidiary or any of their assets or properties is bound or subject; (iii) 
violate any statute, law or regulation of any jurisdiction (which violation 
would affect the validity of the transaction contemplated hereby or otherwise 
would materially adversely affect the business of the Surviving Corporation 
after the Effective Time) or any order, judgment, injunction, award or decree 
of any court, arbitrator or governmental or regulatory body applicable to or 
binding upon Pacific or any Subsidiary or any of their securities, 
properties, assets or business; (iv) violate any material Permit; (v) except 
with respect to change of control provisions in customer contracts, require 
any filing with, notice to, or approval or consent of any foreign, federal, 
state, local or other governmental or regulatory body or any other person or 
entity; (vi) give rise to any obligation to make any material payment; or 
(vii) result in the creation of any Encumbrance on the assets or properties 
of Pacific or any Subsidiary, excluding from the foregoing clauses (ii), 
(iii), (iv) and (v) any exceptions to the foregoing that, in the aggregate, 
would not have a Pacific Material Adverse Effect on the business of Pacific 
or on the ability of Pacific to consummate the transactions contemplated 
hereby, and the following: (a) the filing of the Merger Certificate with the 
Secretary of State of Delaware (b) filings with various state blue sky 
authorities, (c) the filing with Nasdaq of an application for listing of the 
shares of Pacific Common Stock to be issued in the Merger and (d) the filing 
with the SEC of a regitration statement on Form S-4 to register the shares of 
Pacific Common Stock to be issued in the Merger.

       3.13   ACTIONS AND PROCEEDINGS. Except as set forth on the PACIFIC 
DISCLOSURE SCHEDULE, there are no outstanding orders, judgments, injunctions, 
awards or decrees of any court, governmental or regulatory body or 
arbitration tribunal against or involving Pacific, any of the Subsidiaries or 
any of their securities, assets, or properties.  There are no actions, suits 
or claims or legal, judicial, administrative or arbitral proceedings or 
investigations (whether or not the defense thereof or liabilities in respect 
thereof are covered by insurance) pending or, to the best knowledge of 
Pacific, threatened against or involving Pacific any of the Subsidiaries, or 
any of their securities, assets or properties.

                                       12
<PAGE>

       3.14   CONTRACTS AND OTHER AGREEMENTS.  Section 3.14 of the PACIFIC 
DISCLOSURE SCHEDULE sets forth a correct and complete list all of the 
following currently effective contracts: 

                            (i)    written contracts and other agreements 
with or for the benefit of any current or former officer, director, 
stockholder or employee of Pacific or any Subsidiary or any Subsidiary 
involving more than $5,000, (provided in the case of a loan by Pacific or any 
Subsidiary to any such person, the PACIFIC DISCLOSURE SCHEDULE shall list all 
such loan arrangements, whether or not in writing, involving at least $1,000) 
and contracts and other agreements for the payment of fees or other 
consideration to any entity in which Pacific or any Subsidiary has an 
interest;

                            (ii)   contracts and other agreements with any 
labor union or association representing any employee of Pacific or any 
Subsidiary or otherwise providing for any form of collective bargaining;

                            (iii)  contracts and other agreements for the 
purchase or sale of materials, supplies, equipment, merchandise or services 
that contain an escalation,  renegotiation or redetermination clause or that 
obligate Pacific or any Subsidiary to purchase all or substantially all of 
its requirements of a particular product from a supplier, or for periodic 
minimum purchases of a particular product from a supplier;

                            (iv)   contracts and other agreements for the 
sale of any of the assets or properties of Pacific or any Subsidiary other 
than in the ordinary course of business or for the grant to any person of any 
options, rights of first refusal, or preferential or similar rights to 
purchase any of such assets or properties;

                            (v)    partnership or joint venture agreements;

                            (vi)   contracts with agents or foreign 
representatives regarding the sales or marketing of the services or products 
of Pacific or any Subsidiary;

                            (vii)  contracts or other agreements under which 
Pacific or any Subsidiary agrees to act as surety or guarantor for or to 
indemnify any party (other than required indemnification provisions in 
customer contracts) or to share the tax liability of any party;

                            (viii) contracts, options, outstanding purchase 
orders and other agreements for the purchase of any material asset, tangible 
or intangible;

                            (ix)   contracts and other agreements with 
customers, suppliers or other parties for the sharing of fees, the rebating 
of charges or other similar arrangements other than such contracts entered 
into in the normal course of business;

                            (x)    contracts and other agreements containing 
obligations or liabilities of any kind to holders of the securities of 
Pacific or of any Subsidiary as such (including, without limitation, an 
obligation to register any of such securities under any federal or state 
securities laws) and contracts obligating Pacific or any Subsidiary to issue 
or repurchase any securities;

                                       13
<PAGE>

                            (xi)   contracts and other agreements containing 
covenants of Pacific or any Subsidiary not to compete in any line of business 
or with any person or entity or covenants of any other person or entity not 
to compete with Pacific or any Subsidiary in any line of business;

                            (xii)  contracts and other agreements relating to 
the acquisition by Pacific or any Subsidiary of any operating business or the 
capital stock of any other person or entity;

                            (xiii) contracts and other agreements requiring 
the payment to any party of a brokerage or sales commission or a finder's or 
referral fee; 

                            (xiv)  contracts, indentures, mortgages, 
promissory notes, debentures loan agreements, guaranties, security 
agreements, pledge agreements, and other agreements and instruments relating 
to the borrowing or lending of money or securing any such liability;

                            (xv)   any agreement or series of related 
agreements requiring aggregate payments by or to Pacific or any Subsidiary of 
more than $5,000;

                            (xvi)  contracts under which Pacific or any 
Subsidiary will acquire or has acquired ownership of, or license to, 
intangible property, including software other than commercially available 
end-user licenses; and

                            (xvii) any other material contract or other 
agreement whether or not made in the ordinary course of business.

       There have been delivered or made available to Procept true and 
complete copies of all of the contracts and other agreements (and all 
amendments, waivers or other modifications thereto) set forth in Section 3.14 
of the PACIFIC DISCLOSURE SCHEDULE.  All of such contracts and other 
agreements are valid, subsisting, in full force and effect, binding upon 
Pacific or a Subsidiary (as the case may be), and to the best knowledge of 
Pacific, binding upon the other parties thereto in accordance with their 
terms.  Other than defaults which would not, either singly or in the 
aggregate, have a Pacific Material Adverse Effect, none of Pacific or any 
Subsidiary is not in default under any of such scheduled contracts, nor, to 
the best knowledge of Pacific, is any other party to any such contract or 
other agreement in default thereunder, nor does any condition exist that 
constitutes or with notice or lapse of time or both would constitute a 
default thereunder.

       3.15   REAL PROPERTY; LEASES. None of Pacific or any Subsidiary does 
not own any real property or any buildings or other structures and does not 
have any options or any contractual obligations to purchase or acquire any 
interest in real property except as set forth in Section 3.15 of the PACIFIC 
DISCLOSURE SCHEDULE.  Section 3.15 of the PACIFIC DISCLOSURE SCHEDULE sets 
forth a correct and complete list of all leases of real property to which 
Pacific is a party (collectively, the "LEASES"). True and complete copies of 
the leases and all amendments, modifications and supplemental agreements 
thereto have been delivered by Pacific to Procept.  The Leases are in full 
force and effect and to the best knowledge of Pacific, are binding and 
enforceable against each of the parties thereto in accordance with their 
respective terms.  To the best knowledge of Pacific no party to any Lease has 
given notice to any other party thereto claiming the existence 

                                       14
<PAGE>

or occurrence of a breach or default thereunder and there has not occurred 
any event or circumstances which constitutes, or with the passage of time or 
the giving of notice would constitute, a breach or default thereunder other 
than defaults which would not, either singly or in the aggregate, have a 
Pacific Material Adverse Effect.

       3.16   TANGIBLE PROPERTY.  Each of Pacific and the Subsidiaries has 
good and marketable title to, free and clear of all Encumbrances, or 
otherwise has the unrestricted right to use, each item of equipment, 
furniture, leasehold improvements, fixtures, vehicles, structures, any 
related capitalized items and other tangible property material to the 
business of Pacific or such Subsidiary ("TANGIBLE PROPERTY").  All such 
Tangible Property is in good and sufficient operating condition and repair, 
ordinary wear and tear excepted, and to the best knowledge of Pacific, none 
of Pacific or such Subsidiary has received notice that any of its Tangible 
Property is in violation of any existing law or any building, zoning, health, 
safety or other ordinance, code or regulation.

       3.17   INTELLECTUAL PROPERTY.

              (a)    To the knowledge of Pacific, each of Pacific and the 
Subsidiaries owns, or is licensed to use, or otherwise has the right to use 
all patents, trademarks, service marks, trade names, trade secrets, logos, 
franchises, and copyrights, and all applications for any of the foregoing, 
and all technology, inventions, trade secrets, know-how, computer software 
and processes to the extent material to the conduct of its business as now 
conducted (collectively, the "PROPRIETARY RIGHTS").  Pacific has previously 
delivered to Procept a certified list of all such patents and registered 
copyrights and trademarks, and all applications therefor (the "PACIFIC 
REGISTERED RIGHTS"). All of the Pacific Registered Rights owned by Pacific or 
any Subsidiary, and to the best knowledge of Pacific, all Pacific Registered 
Rights licensed to Pacific or any Subsidiary have been registered in, filed 
in or issued by the United States Patent and Trademark Office, the United 
States Register of Copyrights, or the corresponding offices of other 
jurisdictions as identified in Section 3.17 of the PACIFIC DISCLOSURE 
SCHEDULE, and have been properly maintained and renewed in accordance with 
all applicable provisions of law and administrative regulations in the United 
States and in each such other jurisdiction.

              (b)    To the best knowledge of Pacific, the businesses of 
Pacific and the Subsidiaries as currently conducted does not infringe upon 
the proprietary rights of others, nor has Pacific or any Subsidiary received 
any notice or claim from any third party of such infringement by Pacific or 
any Subsidiary .  Pacific is not aware of any material unlicensed 
infringement by any third party on, or any issued competing claim of right to 
use or own any of, the Proprietary Rights of Pacific.  To the best knowledge 
of Pacific, none of the activities of the employees of Pacific or any 
Subsidiary on behalf of Pacific or such Subsidiary violates any agreements or 
arrangements that any such employees have with former employers.  

       3.18   TITLE TO ASSETS; LIENS.  Each of Pacific and the Subsidiaries 
owns outright, leases or rents, and has good title to all of its material 
assets and properties, including, without limitation, all of the assets and 
properties reflected on the Pacific Interim Balance Sheet, free and clear of 
any Encumbrance, except for (i) assets and properties disposed of in the 
ordinary course of business, (ii) Encumbrances securing the claims of 
materialmen, carriers, landlords and like persons, all of which are not yet 
due and payable, (iii) liens for taxes not yet due and payable or 

                                       15

<PAGE>

for taxes being contested in good faith by appropriate proceedings, or (iv) 
Encumbrances reflected on the Pacific Interim Balance Sheet.

       3.19   EMPLOYEE BENEFIT PLANS.  Section 3.19 of the PACIFIC DISCLOSURE 
SCHEDULE sets forth a correct and complete list of all pension, profit 
sharing, retirement, deferred compensation, welfare, insurance, disability, 
bonus, vacation pay, severance pay and similar plans, programs or 
arrangements, including without limitation all employee benefit plans as 
defined in Section 3(3) of the Employee Retirement Income Security Act of 
1974, as amended ("ERISA") with respect to which Pacific is the "PLAN 
SPONSOR" within the meaning of Section 3(16)(B) of ERISA, or in which Pacific 
or any Subsidiary participates (the "PLANS").  None of Pacific or any 
Subsidiary has never maintained or contributed to any "MULTIEMPLOYER PLAN" as 
defined in Section 4001(a)(3) of ERISA, and none of Pacific or any Subsidiary 
has incurred any material liability under Sections 4062, 4063 or 4201 of 
ERISA.  Each Plan which is intended to be qualified under Section 401(a) or 
501(c)(9) of the Internal Revenue Code of 1986, as amended (the "CODE"), has 
received a favorable determination letter from the Internal Revenue Service.  
Each Plan has been administered in all material respects in accordance with 
the terms of such Plan and the provisions of any and all applicable statutes, 
orders or governmental rules or regulations, including without limitation 
ERISA and the Code.  To the knowledge of Pacific, nothing has been done or 
omitted to be done with respect to any Plan which is intended to comply with 
Section 401(a) of the Code that would adversely affect the qualified status 
of such Plan or result in any material liability on the part of Pacific 
including, without limitation, under Title I of ERISA or Section 4975 of the 
Code (other than an operational violation that could be corrected through the 
Internal Revenue Service's Administrative Policy Regarding Self-Correction).  
All material reports, returns, notices and documents required to be filed 
with respect to all Plans, including without limitation annual reports on 
Form 5500, have been timely filed.  No "REPORTABLE EVENT" as defined at 
Section 4043 of ERISA, other than any such event for which the thirty-day 
notice period has been waived, has occurred with respect to any Plan subject 
to Title IV of ERISA, and no event has occurred requiring notices to be 
provided under Section 4063(a) of ERISA.  Except as set forth on the PACIFIC 
DISCLOSURE SCHEDULE, all contributions required by law or the terms of any 
Plan have been made.  With respect to all Plans subject to Title IV of ERISA, 
such Plans have no unfunded benefit liabilities and all premium payments to 
the Pension Benefit Guaranty Corporation with respect to such Plans have been 
made.  Except as set forth on the PACIFIC DISCLOSURE SCHEDULE, all 
contributions to such Plans subject to Section 412 of the Code required to be 
made under the minimum funding requirements of Section 412 of the Code have 
been made or accrued.  Except as set forth on the PACIFIC DISCLOSURE 
SCHEDULE, all claims for welfare benefits incurred by employees of Pacific or 
any Subsidiary on or before the Closing are or will be fully covered by 
third-party insurance policies or programs.  None of the Plans is a defined 
benefit pension plan that is subject to Title IV of ERISA, nor has Pacific 
ever maintained such a plan.  Except for continuation of health coverage to 
the extent required under Section 4980B of the Code or as otherwise set forth 
in this Agreement, there are no obligations under any Plan providing group 
health expense reimbursements benefits after termination of employment.  
Complete copies of the following documents with respect to each Plan (as 
applicable) have been delivered to Procept: (i) each relevant Plan document 
and subsequent amendment thereto; (ii) each trust agreement, group annuity 
contract, insurance policy or contract; (iii) each Form 5500 series annual 
report with each required schedule and attachment for each of the three (3) 
most recent plan years; (iv) the most recent IRS determination letter; and 
(v) the most recent summary plan description and each summary of material 
modification thereto.  For purposes of this 

                                       16
<PAGE>

Section 3.19, references to Pacific include Pacific and its ERISA Affiliates. 
 An "ERISA Affiliate" of Pacific means any trade or business (whether or not 
incorporated) that together with Pacific would have been deemed a "single 
employer" within the meaning of Section 4001(b) of ERISA or Section 414(m) of 
the Code at any time within the five-year period ending on the Closing Date.

       3.20   EMPLOYEE RELATIONS.  Pacific has approximately six full-time 
equivalent employees and generally enjoys good employer-employee relations.  
The number of employees of each Subsidiary is set forth on the PACIFIC 
DISCLOSURE SCHEDULE.  None of Pacific's or any Subsidiary's employees are 
represented by any labor union.  None of Pacific or any Subsidiary is 
delinquent in payments to any of its employees or consultants for any wages, 
salaries, commissions, bonuses or other direct compensation for any services 
performed by them to the date hereof or amounts required to be reimbursed to 
such employees or consultants.  Neither Procept nor Pacific will by reason of 
the Merger or anything done prior to the Closing be liable to any Pacific 
employees for severance pay or any other payments (other than accrued salary, 
vacation or sick pay in accordance with Pacific's normal policies) in the 
event any such employees are terminated.  Correct and complete information as 
to all current directors, officers, employees or consultants of Pacific and 
the Subsidiaries including, in each case, name, current job title and annual 
rate of compensation has been provided by Pacific to Procept.

       3.21   RELATIONSHIPS WITH AFFILIATES.  Except as set forth in Section 
3.21 of the PACIFIC DISCLOSURE SCHEDULE, to the best knowledge of Pacific, no 
officer or director of Pacific or any Subsidiary has directly or indirectly 
any interest in, (i) any property or assets of Pacific or any Subsidiary 
(except as a stockholder of Pacific), (ii) any competitor or customer of 
Pacific or any Subsidiary, (iii) any supplier or lender to Pacific or any 
Subsidiary, or (iv) any party to any material contract or agreement with 
Pacific or any Subsidiary.

       3.22   INSURANCE.  Section 3.22 of the PACIFIC DISCLOSURE SCHEDULE 
sets forth a correct and complete list of all policies or binders of fire, 
liability, product liability, workmen's compensation, vehicular, directors' 
and officers' and other insurance held by or on behalf of Pacific and the 
Subsidiaries specifying in each case the type and scope of coverage, the 
amount of coverage, the premium, the insurer, the expiration date and all 
claims made thereunder within the past three years.  Such policies and 
binders are in full force and effect, are reasonably believed to be adequate 
for the businesses engaged in by Pacific and the Subsidiaries, are in 
conformity with the requirements of all leases or other agreements to which 
Pacific and the Subsidiaries are parties and are valid and enforceable in 
accordance with their terms.  All premiums due under such policies and 
binders have been paid, and none of Pacific or any Subsidiary is in default 
with respect to any provision contained in any such policy or binder nor has 
Pacific failed to give any notice or present any claim under any such policy 
or binder in due and timely fashion.  There are no outstanding unpaid claims 
under any such policy or binder.  None of Pacific or any Subsidiary has 
received notice of cancellation or non-renewal of, or any material amendment 
to, or any material increase in deductibles or premiums under, any such 
policy or binder.  Correct and complete copies of certificates of insurance 
with respect to all such policies and binders have been provided by Pacific 
to Procept.

       3.23   BROKERAGE.  Other than the brokerage fee disclosed on the 
PACIFIC DISCLOSURE SCHEDULE, no broker, finder, agent or similar intermediary 
has acted on behalf of Pacific in 

                                       17
<PAGE>

connection with this Agreement or the transactions contemplated hereby, and 
there are no brokerage commissions, finders fees or similar fees or 
commissions payable in connection therewith based on any agreement, 
arrangement or understanding with, or any action taken by Pacific.

       3.24   HAZARDOUS MATERIALS.  None of Pacific or any Subsidiary has 
generated, used or handled any Hazardous Materials (as defined below), nor 
has Pacific treated, stored or disposed of any Hazardous Materials at any 
site owned or leased at any time by Pacific or any Subsidiary or shipped any 
Hazardous Materials for treatment, storage or disposal at any other site or 
facility, except in compliance with all applicable laws.  To the knowledge of 
Pacific, no other person has generated, used, handled, stored or disposed of 
any Hazardous Materials at any site owned or premises leased by Pacific or 
any Subsidiary at any time or at any site in which Pacific or any Subsidiary 
presently holds a mortgage or similar interest, nor has there been or is 
there threatened any release of any Hazardous Materials on or at any such 
site or premises.  None of Pacific or any Subsidiary presently operates or 
leases nor have any of them operated or leased any site on which, underground 
storage tanks are or were located and which tanks are the responsibility of 
Pacific or such Subsidiary to operate.  To the knowledge of Pacific, without 
investigation, no lien has been imposed by any governmental agency in 
connection with the presence of any Hazardous Materials on any property, 
facility, machinery, or equipment operated or leased by Pacific or any 
Subsidiary or in which Pacific or any Subsidiary holds any mortgage, lien, or 
similar interest.  For purposes of this Section 3.24, "HAZARDOUS MATERIALS" 
shall mean and include any "HAZARDOUS WASTE" as defined in either the United 
States Resource Conservation and Recovery Act, 42 U.S.C. 6901, or regulations 
adopted pursuant to said Act, and also any "HAZARDOUS SUBSTANCES" or 
"HAZARDOUS MATERIALS" as defined in the United States Comprehensive 
Environmental Response, Compensation and Liability Act, 42 U.S.C. 9601, but 
excludes ordinary and customary materials in quantities reasonably required 
to be used by Pacific or any Subsidiary in the ordinary course of such 
company's business.

       3.25   FULL DISCLOSURE.  All documents and other papers delivered by 
or on behalf of Pacific in connection with this Agreement and the 
transactions contemplated hereby are true, complete and authentic.  No 
representation, warranty or statement of Pacific made in this Agreement or in 
any Exhibit or the PACIFIC DISCLOSURE SCHEDULE hereto or in any document, 
statement or certificate furnished to Procept pursuant to this Agreement 
contains any untrue statement of a material fact or omits to state a material 
fact required to be stated therein or necessary to make the statements made, 
in light of the circumstance under which they were made, not false or 
misleading.

           SECTION 4 - REPRESENTATIONS AND WARRANTIES OF PROCEPT

       Except as set forth on the disclosure schedule (the "PROCEPT 
DISCLOSURE SCHEDULE") delivered to Procept on the date hereof, (regardless of 
whether the PROCEPT DISCLOSURE SCHEDULE is referenced in any particular 
subsection of this Section 4), the subsection numbers of which are numbered 
to correspond to the subsection numbers of this Agreement to which they refer 
(provided that disclosure thereon under any subsection number shall be 
disclosure for any section hereof), Procept represents and warrants to 
Procept as set forth below:

                                       18
<PAGE>

       4.1    ORGANIZATION AND QUALIFICATION. Procept is a corporation duly 
organized, validly existing and in good standing under the laws of the state 
or other jurisdiction of its incorporation and has full corporate power and 
authority to own, lease and operate its assets, properties and business and 
to carry on its business as now being and as heretofore conducted.  Procept 
is qualified or is otherwise authorized to transact business as a foreign 
corporation in each jurisdiction (in the United States and outside of the 
United States) in which the failure to so qualify would have a material 
adverse effect on the business or financial condition of Procept (other than 
changes that are the effect of economic factors affecting the economy or the 
pharmaceutical industry as a whole) (a "Procept Material Adverse Effect"), 
all of which jurisdictions are identified in Section 4.1 of the PROCEPT 
DISCLOSURE SCHEDULE.

       4.2    CAPITALIZATION.

              4.2.1  OUTSTANDING CAPITAL STOCK.  Procept's authorized capital 
stock consists of 30,000,000 shares of Common Stock, $.01 par value per 
share, of which 3,001,832 shares are issued and outstanding as of November 6, 
1998, and 1,000,000 shares of Preferred Stock, $.01 par value per share, none 
of which shares are issued and outstanding.  Except as disclosed in Procept's 
proxy statement for its annual meeting of stockholders held on May 18, 1998, 
Procept is not aware of any record or beneficial holder of more than five 
percent (5%) of the outstanding shares of Procept Stock.  The outstanding 
shares of Procept Stock are duly authorized, validly issued, fully paid, and 
nonassessable and have been issued in compliance with all charter documents 
of Procept and all applicable federal and state laws. Except as set forth in 
this Section 4.2.1, no other capital stock of Procept is authorized or 
outstanding.

              4.2.2  OPTIONS OR OTHER RIGHTS.  Except as set forth in the 
PROCEPT DISCLOSURE SCHEDULE, (i) no subscription, warrant, option, preemptive 
right, convertible security or other right (contingent or otherwise) to 
purchase or acquire any shares of capital stock or other security of Procept 
issued by Procept is authorized or outstanding, (ii) there is no commitment 
or offer by Procept to issue or provide any such subscription, warrant, 
option, preemptive right, convertible security or other right or to issue or 
distribute to holders of any shares of its capital stock any evidences of 
indebtedness or assets of Procept, (iii) Procept has no obligation 
(contingent or otherwise) to purchase, redeem or otherwise acquire any shares 
of its capital stock or any interest therein or to pay any dividend or make 
any other distribution in respect thereof, (iv) there are no restrictions on 
the transfer of Procept's capital stock other than those arising from 
securities laws, and (v) there are no voting trusts, proxies or other 
agreements, instruments or understandings with respect to outstanding shares 
of Procept's capital stock to which Procept is a party. 

       4.3    AUTHORITY TO EXECUTE AND PERFORM AGREEMENTS.  Subject to the 
requirement to obtain approval of its stockholders to consummate the Merger 
under the DGCL, Procept has the requisite corporate power and authority to 
execute and deliver this Agreement and each agreement, document and 
instrument contemplated by this Agreement to which it is a party, to 
consummate the transactions contemplated hereby and thereby and to perform 
fully its respective obligations hereunder and thereunder.  The execution, 
delivery and performance of this Agreement and each such other agreement, 
document and instrument to which it is a party and the consummation of the 
transactions contemplated hereby and thereby have been duly authorized by all 
necessary corporate action on the part of Procept.  This Agreement and each 

                                       19
<PAGE>

agreement, document and instrument to which it is a party executed and 
delivered pursuant to this Agreement constitutes, or when executed and 
delivered will constitute, valid and binding obligations of Procept, 
enforceable in accordance with their terms.

       4.4    SUBSIDIARIES AND OTHER AFFILIATES.  Except as set forth on the 
PROCEPT DISCLOSURE SCHEDULE Procept does not have any subsidiary or directly 
or indirectly own or have any investment in any of the capital stock of, or 
any other interest in, any other person or entity.

       4.5    CHARTER AND BY-LAWS; BOOKS AND RECORDS. Procept has heretofore 
delivered or made available to Procept true and complete copies of its 
Certificate of Incorporation (certified by the Secretary of State or 
comparable authority of its jurisdiction of incorporation) and By-laws as in 
effect on the date hereof, and corporate minute books.  Procept is not in 
default in the performance, observation or fulfillment of either its charter 
or By-laws.  The minute books of Procept contain true and complete records of 
all meetings and consents in lieu of meetings of the Board of Directors and 
of the stockholders of Procept prior to the date hereof, and accurately 
reflect all transactions referred to in such minutes and consents in lieu of 
meetings.  The stock books of Procept are true, complete and correct.  The 
general ledgers and books of account of Procept to which Procept and its 
representatives have been given access are correct and complete in all 
material respects and have been maintained in accordance with good business 
practice.

       4.6    SEC REPORTS.  Procept has previously delivered to Procept its 
(i) Annual Report on Form 10-K/A for the year ended December 31, 1997 (the 
"Procept 10-K"), as filed with the Securities and Exchange Commission (the 
"SEC"), (ii) the proxy statement relating to Procept's annual meeting of 
stockholders held on May 18, 1998 and (iii) all other reports filed by 
Procept with the SEC under the Exchange, since January 1, 1998.  As of their 
respective dates, such reports complied in all material respects with 
applicable SEC requirements and did not contain any untrue statement of a 
material fact or omit to state a material fact required to be stated therein 
or necessary to make the statements therein, in light of the circumstances 
under which they were made, not misleading.  Procept has timely filed with 
the SEC all reports required to be filed under Sections 13, 14 or 15(d) of 
the Exchange Act since becoming registered under the Exchange Act.

       4.7    FINANCIAL STATEMENTS.  The consolidated financial statements 
contained in the Procept 10-K and in Procept's quarterly report on Form 10-Q 
for the quarter ended September 30, 1998 (the "PROCEPT 10-Q") have been 
prepared from, and are in accordance with, the books and records of Procept 
and fairly present the consolidated financial condition, results of 
operations and cash flows of Procept as of the dates and for the periods 
presented therein, all in accordance with generally accepted accounting 
principles applied on a consistent basis, except as otherwise indicated 
therein and subject (in the case of the unaudited financial statements 
included in the Procept 10-Q) to normal year-end and audit adjustments and 
footnote disclosures, which in the aggregate are not material.

       4.8    ABSENCE OF UNDISCLOSED LIABILITIES.  Except as set forth in the 
PROCEPT DISCLOSURE SCHEDULE at December 31, 1997, Procept had no material 
liabilities of any nature, whether accrued, absolute, contingent or otherwise 
(including without limitation, liabilities as guarantor or otherwise with 
respect to obligations of others or liabilities for taxes due or then accrued 
or to become due), required to be reflected or disclosed in the balance sheet 
dated December 31, 1997 

                                       20

<PAGE>

(or the notes thereto) included in the Procept 10-K (the "PROCEPT BALANCE 
SHEET") that were not adequately reflected or reserved against on such 
balance sheet.  Except as set forth in the PROCEPT DISCLOSURE SCHEDULE, 
Procept has no such liabilities, except as and to the extent (i) adequately 
reflected and reserved against in the Procept Balance Sheet, (ii) adequately 
reflected and reserved against in the Procept unaudited balance sheet dated 
September 30, 1998 included in the Procept 10-Q (the "PROCEPT INTERIM BALANCE 
SHEET"), or (iii) incurred since December 31, 1997 in the ordinary course of 
business and not material in amount, either individually or in the aggregate.

       4.9    NO MATERIAL ADVERSE CHANGE. Since December 31, 1997, except as 
set forth in the PROCEPT DISCLOSURE SCHEDULE, there has not been:

                            (i)    any material adverse change in the assets, 
liabilities, condition (financial or otherwise), results of operation, 
business or prospects of Procept or any occurrence or circumstance which 
reasonably could be expected to result in such a material adverse change;

                            (ii)   any material change in the method of 
operating the business of Procept, in the manner of keeping the books, 
accounts or records of Procept, or in any accounting method or practice of 
Procept;

                            (iii)  any sale, lease, mortgage, pledge, 
encumber, abandonment or disposition of, or agreement to sell, lease, 
mortgage, pledge, encumber, abandon or dispose of, any material assets or 
properties of Procept, other than in the usual and ordinary course of 
business;

                            (iv)   any material transaction, commitment, 
contract or agreement entered into by Procept, or any relinquishment or 
abandonment by Procept of any material contract or right, or any 
modification, waiver, amendment, release, recision, or termination of any 
material term, condition or provision of any contract pertaining to Procept 
(other than any satisfaction by performance in accordance with the terms 
thereof), other than in the usual and ordinary course of business; 

                            (v)    any adverse relationships or conditions 
with employees, suppliers, lenders, customers or governmental agencies that 
could reasonably be anticipated to have a Pacific Material Adverse Effect on 
Procept or its business;

                            (vi)   any acquisition by Procept (other than 
property or interests therein acquired in the ordinary course of its lending 
business) of all or any part of the assets, properties, capital stock or 
business of any other person or entity;

                            (vii)  any redemption or other acquisition by 
Procept of any of its capital stock or any declaration, setting aside or 
payment of any dividend or distribution of any kind with respect to shares of 
its capital stock;

                            (viii) any loan or advance by Procept to any 
stockholder, officers, director or consultant, or any other loan or advance 
other than in the ordinary course of business; or

                                       21
<PAGE>

                            (ix)   except as set forth in the PROCEPT 
DISCLOSURE SCHEDULE, any new employment or consulting agreement, any increase 
in compensation, bonus or other benefits payable or to become payable by 
Procept to any director, officer or employee, other than regularly scheduled 
increases consistent with past practice in the ordinary course of business, 
or any new grant of severance or termination rights, or increase in rights or 
benefits payable under existing severance or termination policies or 
agreements, to any director, officer or employee of Procept. 

       4.10   TAX MATTERS.  

              (a)    DEFINITION OF TAXES.  For the purposes of this 
Agreement, "Tax" or, collectively, "Taxes", means any and all federal, state, 
local and foreign taxes, assessments and other governmental charges, duties, 
impositions and liabilities in the nature of a tax including taxes based upon 
or measured by gross receipts, income, profits, sales, use and occupation, 
and value added, ad valorem, transfer, franchise, withholding, payroll, 
recapture, employment, excise and property taxes, together with all interest, 
penalties and additions imposed with respect to such amounts and any 
obligations under any agreements or arrangements with any other person with 
respect to such amounts and including any liability for taxes of a 
predecessor entity. 

              (b)    TAX RETURNS AND AUDITS.  Except as set forth in the 
Procept Disclosure Schedule:

                            (i)    Procept has prepared and filed all 
required federal, state, local and foreign returns, estimates, information 
statements and reports ("Returns") required to be filed relating to any and 
all Taxes concerning or attributable to Procept or its operations and such 
Returns are true and correct in all material respects and have been completed 
in all material respects in accordance with applicable law or, with respect 
to any Taxes payable, an adequate reserve has been established on the Procept 
Interim Balance Sheet.

                            (ii)   Procept: (A) has paid or accrued all Taxes 
set forth on its Returns, and (B) has withheld and paid (or will pay at the 
time required) with respect to its employees all federal and state income 
taxes, FICA, FUTA and other Taxes required to be withheld.

                            (iii)  Procept is not delinquent in any material 
respect in the payment of any Tax nor is there any material Tax deficiency 
outstanding, proposed or assessed against Procept, nor has Procept executed 
any waiver of any statute of limitations on or extending the period for the 
assessment or collection of any Tax.

                            (iv)   Other than the audits set forth in the 
Procept Disclosure Schedule, no audit or other examination of any Return of 
Procept is currently in progress, nor has Procept been notified of any 
request for such an audit or other examination.

                            (v)    Procept did not have, as of September 30, 
1998, any liabilities, whether asserted or unasserted, contingent or 
otherwise, for unpaid federal, state, local and foreign Taxes which have not 
been accrued or reserved against in accordance with GAAP on the Procept 
Interim Balance Sheet, and Procept has not incurred any such liabilities 
since such date except in the ordinary course of business and consistent with 
past practices.

                                       22
<PAGE>

                            (vi)   There are (and as of immediately following 
the Effective Date there will be) no liens, pledges, charges, claims, 
security interests or other encumbrances of any sort ("Liens") of a material 
nature on the assets of Procept relating to or attributable to Taxes, except 
for Liens for Taxes not yet due and payable or that are being contested in 
good faith by appropriate proceedings. 

                            (vii)  Procept has not received written or oral 
notice of any claim relating or attributable to Taxes that, if adversely 
determined, would result in any Lien on the assets of Procept.

                            (viii) None of Procept's assets are treated as 
"tax-exempt use property" within the meaning of Section 168(h) of the Code.

                            (ix)   As of the Effective Time, there will not 
be any contract, agreement, plan or arrangement, including but not limited to 
the provisions of this Agreement, covering any employee or former employee of 
Procept that, individually or collectively, could give rise to the payment of 
any amount that would not be deductible pursuant to Section 280G of the Code 
or the limitations in Sections 162 of the Code.

                            (x)    Procept has not filed any consent 
agreement under Section 341(f) of the Code or agreed to have Section 
341(f)(2) of the Code apply to any disposition of a subsection (f) asset (as 
defined in Section 341(f)(4) of the Code) owned by Procept.

                            (xi)   Procept is not a party to a tax sharing or 
allocation agreement nor does Procept owe any amount under any such agreement.

                            (xii)  Procept is not nor has been at any time 
during the period specified in Section 897(c)(1)(A)(ii) of the Code, a 
"United States real property holding corporation" within the meaning of 
Section 897(c)(2) of the Code.

                            (xiii) Procept has agreed to, or is required to, 
make any adjustments under Section 481(c) of the Code by reason of a change 
in accounting method or otherwise.

       4.11   COMPLIANCE WITH LAWS.

              4.11.1 Procept is not in violation in any material respect of 
any order, judgment, injunction, award or decree, or any federal, state, 
local or foreign law, ordinance or regulation or any other requirement of any 
governmental or regulatory body, court or arbitrator, and is in compliance in 
all material respects with all of the foregoing that are applicable to it, 
its business or its assets.  Procept has not received notice of, and there 
has not been any citation, fine or penalty imposed or asserted against any of 
them for, any such violation or alleged violation that has not been favorably 
and fully resolved.

              4.11.2 Procept holds all licenses, permits, certificates, 
franchises, orders or approvals of any federal, state, local or foreign 
governmental or regulatory body, that are material to the conduct of 
Procept's business and the uses of its assets (collectively, "PERMITS") 
necessary to operate its business as presently conducted.  The PROCEPT 
DISCLOSURE SCHEDULE 

                                       23
<PAGE>

contains a true and complete list of all such permits as of the date hereof. 
Such Permits are in full force and effect and the validity and effectiveness 
of such Permits will not be affected by the transactions contemplated hereby. 
 No violations are or have been recorded with any governmental or regulatory 
body in respect of any Permit, no proceeding is pending or, to the best 
knowledge of Procept, threatened to revoke or limit any Permit, and Procept 
knows of no grounds for any such revocation or limitation.

       4.12   CONSENTS; NO BREACH. All consents, permits, authorizations and 
approvals from any person or entity that are required pursuant to applicable 
law, or agreement or otherwise in connection with the execution, delivery and 
performance of this Agreement by Procept are set forth in Section 4.12 of the 
PROCEPT DISCLOSURE SCHEDULE, other than those which the failure to obtain 
would not affect the validity of this transaction or materially adversely 
affect the business of the Surviving Corporation after the Effective Time.  
Subject to any prior approval requirements set forth in Section 4.12 of the 
PROCEPT DISCLOSURE SCHEDULE, the execution, delivery and performance of this 
Agreement and the consummation of the transactions contemplated hereby will 
not (i) violate any provision of the Certificate of Incorporation or By-laws 
of Procept; (ii) violate, conflict with or result in the breach of any of the 
terms or conditions of, result in a material modification of, or otherwise 
give any other contracting party the right to terminate, or constitute (or 
with notice or lapse of time or both constitute) a default under, any 
material instrument, contract or other agreement to which Procept is a party 
or to which Procept or any of its assets or properties is bound or subject; 
(iii) violate any statute, law or regulation of any jurisdiction (which 
violation would affect the validity of the transaction contemplated hereby or 
otherwise would materially adversely affect the business of the Surviving 
Corporation after the Effective Time) or any order, judgment, injunction, 
award or decree of any court, arbitrator or governmental or regulatory body 
applicable to or binding upon Procept or its securities, properties, assets 
or business; (iv) violate any material Permit; (v) except with respect to 
change of control provisions in customer contracts, require any filing with, 
notice to, or approval or consent of any foreign, federal, state, local or 
other governmental or regulatory body or any other person or entity; (vi) 
give rise to any obligation to make any material payment; or (vii) result in 
the creation of any Encumbrance on the assets or properties of Procept, 
excluding from the foregoing clauses (ii), (iii), (iv) and (v) any exceptions 
to the foregoing that, in the aggregate, would not have a Pacific Material 
Adverse Effect on the business of Procept or on the ability of Procept to 
consummate the transactions contemplated hereby, and the following: (a) the 
filing of the Merger Certificate with the Secretary of State of Delaware (b) 
filings with various state blue sky authorities, (c) the filing with Nasdaq 
of an application for listing of the shares of Procept Common Stock to be 
issued in the Merger and (d) the filing with the SEC of a registration 
statement on Form S-4 to register the shares of Procept Common Stock to be 
issued in the Merger.

       4.13   ACTIONS AND PROCEEDINGS.  Except as set forth on the PROCEPT 
DISCLOSURE SCHEDULE, there are no outstanding orders, judgments, injunctions, 
awards or decrees of any court, governmental or regulatory body or 
arbitration tribunal against or involving Procept or any of its securities, 
assets, or properties.  There are no actions, suits or claims or legal, 
judicial, administrative or arbitral proceedings or investigations (whether 
or not the defense thereof or liabilities in respect thereof are covered by 
insurance) pending or, to the best knowledge of Procept, threatened against 
or involving Procept or any of its securities, assets or properties.

                                       24
<PAGE>

       4.14   CONTRACTS AND OTHER AGREEMENTS.  Section 4.14 of the PROCEPT 
DISCLOSURE SCHEDULE sets forth a correct and complete list all of the 
following currently effective contracts: 

                            (i)    written contracts and other agreements 
with or for the benefit of any current or former officer, director, 
stockholder or employee of Procept involving more than $5,000, (provided in 
the case of a loan by Procept to any such person, the PROCEPT DISCLOSURE 
SCHEDULE shall list all such loan arrangements, whether or not in writing, 
involving at least $1,000) and contracts and other agreements for the payment 
of fees or other consideration to any entity in which Procept has an interest;

                            (ii)   contracts and other agreements with any 
labor union or association representing any employee of Procept or otherwise 
providing for any form of collective bargaining;

                            (iii)  contracts and other agreements for the 
purchase or sale of materials, supplies, equipment, merchandise or services 
that contain an escalation,  renegotiation or redetermination clause or that 
obligate Procept to purchase all or substantially all of its requirements of 
a particular product from a supplier, or for periodic minimum purchases of a 
particular product from a supplier;

                            (iv)   contracts and other agreements for the 
sale of any of the assets or properties of Procept other than in the ordinary 
course of business or for the grant to any person of any options, rights of 
first refusal, or preferential or similar rights to purchase any of such 
assets or properties;

                            (v)    partnership or joint venture agreements;

                            (vi)   contracts with agents or foreign 
representatives regarding the sales or marketing of Procept's services or 
products;

                            (vii)  contracts or other agreements under which 
Procept agrees to act as surety or guarantor for or to indemnify any party 
(other than required indemnification provisions in customer contracts) or to 
share the tax liability of any party;

                            (viii) contracts, options, outstanding purchase 
orders and other agreements for the purchase of any material asset, tangible 
or intangible;

                            (ix)   contracts and other agreements with 
customers, suppliers or other parties for the sharing of fees, the rebating 
of charges or other similar arrangements other than such contracts entered 
into in the normal course of business;

                            (x)    contracts and other agreements containing 
obligations or liabilities of any kind to holders of the securities of 
Procept as such (including, without limitation, an obligation to register any 
of such securities under any federal or state securities laws) and contracts 
obligating Procept to issue or repurchase any Procept securities;

                                       25
<PAGE>

                            (xi)   contracts and other agreements containing 
covenants of Procept not to compete in any line of business or with any 
person or entity or covenants of any other person or entity not to compete 
with Procept in any line of business;

                            (xii)  contracts and other agreements relating to 
the acquisition by Procept of any operating business or the capital stock of 
any other person or entity;

                            (xiii) contracts and other agreements requiring 
the payment to any party of a brokerage or sales commission or a finder's or 
referral fee; 

                            (xiv)  contracts, indentures, mortgages, 
promissory notes, debentures loan agreements, guaranties, security 
agreements, pledge agreements, and other agreements and instruments relating 
to the borrowing or lending of money or securing any such liability;

                            (xv)   any agreement or series of related 
agreements requiring aggregate payments by or to Procept of more than $5,000;

                            (xvi)  contracts under which Procept will acquire 
or has acquired ownership of, or license to, intangible property, including 
software other than commercially available end-user licenses; and

                            (xvii) any other material contract or other 
agreement whether or not made in the ordinary course of business.

       There have been delivered or made available to Pacific true and 
complete copies of all of the contracts and other agreements (and all 
amendments, waivers or other modifications thereto) set forth in Section 4.14 
of the PROCEPT DISCLOSURE SCHEDULE.  All of such contracts and other 
agreements are valid, subsisting, in full force and effect, binding upon 
Procept, and to the best knowledge of Procept, binding upon the other parties 
thereto in accordance with their terms.  Other than defaults which would not, 
either singly or in the aggregate, have a Procept Material Adverse Effect, 
Procept is not in default under any of such scheduled contracts, nor, to the 
best knowledge of Procept, is any other party to any such contract or other 
agreement in default thereunder, nor does any condition exist that 
constitutes or with notice or lapse of time or both would constitute a 
default thereunder.

       4.15   REAL PROPERTY; LEASES.  Procept does not own any real property 
or any buildings or other structures and does not have any options or any 
contractual obligations to purchase or acquire any interest in real property 
except as set forth in Section 4.15 of the PROCEPT DISCLOSURE SCHEDULE.  
Section 4.15 of the PROCEPT DISCLOSURE SCHEDULE sets forth a correct and 
complete list of all leases of real property to which Procept is a party 
(collectively, the "LEASES"). True and complete copies of the leases and all 
amendments, modifications and supplemental agreements thereto have been 
delivered by Procept to Procept.  The Leases are in full force and effect and 
to the best knowledge of Procept, are binding and enforceable against each of 
the parties thereto in accordance with their respective terms.  To the best 
knowledge of Procept no party to any Lease has given notice to any other 
party thereto claiming the existence or occurrence of a breach or default 
thereunder and there has not occurred any event or circumstances which 
constitutes, or with the passage of time or the giving of notice would 
constitute, a breach or default thereunder 

                                       26
<PAGE>

other than defaults which would not, either singly or in the aggregate, have 
a Procept Material Adverse Effect.

       4.16   TANGIBLE PROPERTY.  Procept has good and marketable title to, 
free and clear of all Encumbrances, or otherwise has the unrestricted right 
to use, each item of equipment, furniture, leasehold improvements, fixtures, 
vehicles, structures, any related capitalized items and other tangible 
property material to the business of Procept ("TANGIBLE PROPERTY").  All such 
Tangible Property is in good and sufficient operating condition and repair, 
ordinary wear and tear excepted, and to the best knowledge of Procept, 
Procept has not received notice that any of its Tangible Property is in 
violation of any existing law or any building, zoning, health, safety or 
other ordinance, code or regulation.

       4.17   INTELLECTUAL PROPERTY.

              (a)    To the knowledge of Procept, Procept owns, or is 
licensed to use, or otherwise has the right to use all patents, trademarks, 
service marks, trade names, trade secrets, logos, franchises, and copyrights, 
and all applications for any of the foregoing, and all technology, 
inventions, trade secrets, know-how, computer software and processes to the 
extent material to the conduct of its business as now conducted 
(collectively, the "PROPRIETARY RIGHTS").  Procept has previously delivered 
to Procept a certified list of all such patents and registered copyrights and 
trademarks, and all applications therefor (the "PROCEPT REGISTERED RIGHTS").  
All of the Procept Registered Rights owned by Procept, and to the best 
knowledge of Procept, all Procept Registered Rights licensed to Procept, have 
been registered in, filed in or issued by the United States Patent and 
Trademark Office, the United States Register of Copyrights, or the 
corresponding offices of other jurisdictions as identified in Section 4.17 of 
the PROCEPT DISCLOSURE SCHEDULE, and have been properly maintained and 
renewed in accordance with all applicable provisions of law and 
administrative regulations in the United States and in each such other 
jurisdiction.

              (b)    To the best knowledge of Procept, the business of 
Procept as currently conducted does not infringe upon the proprietary rights 
of others, nor has Procept received any notice or claim from any third party 
of such infringement by Procept.  Procept is not aware of any material 
unlicensed infringement by any third party on, or any issued competing claim 
of right to use or own any of, the Proprietary Rights of Procept.  To the 
best knowledge of Procept, none of the activities of the employees of Procept 
on behalf of Procept violates any agreements or arrangements that any such 
employees have with former employers.

       4.18   TITLE TO ASSETS; LIENS.  Procept owns outright, leases or 
rents, and has good title to all of its material assets and properties, 
including, without limitation, all of the assets and properties reflected on 
the Procept Interim Balance Sheet, free and clear of any Encumbrance, except 
for (i) assets and properties disposed of in the ordinary course of business 
and as disclosed in the PROCEPT DISCLOSURE SCHEDULE, (ii) Encumbrances 
securing the claims of materialmen, carriers, landlords and like persons, all 
of which are not yet due and payable, (iii) liens for taxes not yet due and 
payable or for taxes being contested in good faith by appropriate 
proceedings, or (iv) Encumbrances reflected on the Procept Interim Balance 
Sheet.

                                       27
<PAGE>

       4.19   EMPLOYEE BENEFIT PLANS.  Section 4.19 of the PROCEPT DISCLOSURE 
SCHEDULE sets forth a correct and complete list of all pension, profit 
sharing, retirement, deferred compensation, welfare, insurance, disability, 
bonus, vacation pay, severance pay and similar plans, programs or 
arrangements, including without limitation all employee benefit plans as 
defined in Section 3(3) of the Employee Retirement Income Security Act of 
1974, as amended ("ERISA") with respect to which Procept is the "PLAN 
SPONSOR" within the meaning of Section 3(16)(B) of ERISA, or in which Procept 
participates (the "PLANS"). Procept has never maintained or contributed to 
any "MULTIEMPLOYER PLAN" as defined in Section 4001(a)(3) of ERISA, and 
Procept has not incurred any material liability under Sections 4062, 4063 or 
4201 of ERISA.  Each Plan which is intended to be qualified under Section 
401(a) or 501(c)(9) of the Internal Revenue Code of 1986, as amended (the 
"CODE"), has received a favorable determination letter from the Internal 
Revenue Service.  Each Plan has been administered in all material respects in 
accordance with the terms of such Plan and the provisions of any and all 
applicable statutes, orders or governmental rules or regulations, including 
without limitation ERISA and the Code.  To the knowledge of Procept, nothing 
has been done or omitted to be done with respect to any Plan which is 
intended to comply with Section 401(a) of the Code that would adversely 
affect the qualified status of such Plan or result in any material liability 
on the part of Procept including, without limitation, under Title I of ERISA 
or Section 4975 of the Code (other than an operational violation that could 
be corrected through the Internal Revenue Service's Administrative Policy 
Regarding Self-Correction).  All material reports, returns, notices and 
documents required to be filed with respect to all Plans, including without 
limitation annual reports on Form 5500, have been timely filed.  No 
"REPORTABLE EVENT" as defined at Section 4043 of ERISA, other than any such 
event for which the thirty-day notice period has been waived, has occurred 
with respect to any Plan subject to Title IV of ERISA, and no event has 
occurred requiring notices to be provided under Section 4063(a) of ERISA. 
Except as set forth on the PROCEPT DISCLOSURE SCHEDULE, all contributions 
required by law or the terms of any Plan have been made.  With respect to all 
Plans subject to Title IV of ERISA, such Plans have no unfunded benefit 
liabilities and all premium payments to the Pension Benefit Guaranty 
Corporation with respect to such Plans have been made.  Except as set forth 
on the PROCEPT DISCLOSURE SCHEDULE, all contributions to such Plans subject 
to Section 412 of the Code required to be made under the minimum funding 
requirements of Section 412 of the Code have been made or accrued.  Except as 
set forth on the PROCEPT DISCLOSURE SCHEDULE, all claims for welfare benefits 
incurred by employees of Procept on or before the Closing are or will be 
fully covered by third-party insurance policies or programs.  None of the 
Plans is a defined benefit pension plan that is subject to Title IV of ERISA, 
nor has Procept ever maintained such a plan.  Except for continuation of 
health coverage to the extent required under Section 4980B of the Code or as 
otherwise set forth in this Agreement, there are no obligations under any 
Plan providing group health expense reimbursements benefits after termination 
of employment.  Complete copies of the following documents with respect to 
each Plan (as applicable) have been delivered to Procept: (i) each relevant 
Plan document and subsequent amendment thereto; (ii) each trust agreement, 
group annuity contract, insurance policy or contract; (iii) each Form 5500 
series annual report with each required schedule and attachment for each of 
the three (3) most recent plan years; (iv) the most recent IRS determination 
letter; and (v) the most recent summary plan description and each summary of 
material modification thereto.  For purposes of this Section 4.19, references 
to Procept include Procept and its ERISA Affiliates.  An "ERISA Affiliate" of 
Procept means any trade or business (whether or not incorporated) that 
together with Procept would have been deemed a "single employer" within the 
meaning of Section 

                                       28
<PAGE>

4001(b) of ERISA or Section 414(m) of the Code at any time within the 
five-year period ending on the Closing Date.

       4.20   EMPLOYEE RELATIONS.  Procept has approximately ten full-time 
equivalent employees and generally enjoys good employer-employee relations. 
None of Procept's employees are represented by any labor union.  Procept is 
not delinquent in payments to any of its employees or consultants for any 
wages, salaries, commissions, bonuses or other direct compensation for any 
services performed by them to the date hereof or amounts required to be 
reimbursed to such employees or consultants.  Neither Pacific nor Procept 
will by reason of the Merger or anything done prior to the Closing be liable 
to any Procept employees for severance pay or any other payments (other than 
accrued salary, vacation or sick pay in accordance with Procept's normal 
policies) in the event any such employees are terminated.  Correct and 
complete information as to all current directors, officers, employees or 
consultants of Procept including, in each case, name, current job title and 
annual rate of compensation has been provided by Procept to Pacific.

       4.21   RELATIONSHIPS WITH AFFILIATES.  Except as set forth in Section 
4.21 of the PROCEPT DISCLOSURE SCHEDULE, to the knowledge of Procept, no 
officer or director of Procept has directly or indirectly any interest in, 
(i) any property or assets of Procept (except as a stockholder of Procept), 
(ii) any competitor or customer of Procept, (iii) any supplier or lender to 
Procept, or (iv) any party to any material contract or agreement with Procept.

       4.22   INSURANCE.  Section 4.22 of the PROCEPT DISCLOSURE SCHEDULE 
sets forth a correct and complete list of all policies or binders of fire, 
liability, product liability, workmen's compensation, vehicular, directors' 
and officers' and other insurance held by or on behalf of Procept specifying 
in each case the type and scope of coverage, the amount of coverage, the 
premium, the insurer, the expiration date and all claims made thereunder 
within the past three years. Such policies and binders are in full force and 
effect, are reasonably believed to be adequate for the businesses engaged in 
by Procept, are in conformity with the requirements of all leases or other 
agreements to which Procept is a party and are valid and enforceable in 
accordance with their terms.  All premiums due under such policies and 
binders have been paid, and Procept is not in default with respect to any 
provision contained in any such policy or binder nor has Procept failed to 
give any notice or present any claim under any such policy or binder in due 
and timely fashion.  There are no outstanding unpaid claims under any such 
policy or binder.  Procept has not received notice of cancellation or 
non-renewal of, or any material amendment to, or any material increase in 
deductibles or premiums under, any such policy or binder.  Correct and 
complete copies of certificates of insurance with respect to all such 
policies and binders have been provided by Procept to Pacific.

       4.23   BROKERAGE.  No broker, finder, agent or similar intermediary 
has acted on behalf of Procept in connection with this Agreement or the 
transactions contemplated hereby, and there are no brokerage commissions, 
finders fees or similar fees or commissions payable in connection therewith 
based on any agreement, arrangement or understanding with, or any action 
taken by Procept.

                                       29
<PAGE>

       4.24   HAZARDOUS MATERIALS.  Procept has not generated, used or 
handled any Hazardous Materials (as defined below), nor has Procept treated, 
stored or disposed of any Hazardous Materials at any site owned or leased at 
any time by Procept or shipped any Hazardous Materials for treatment, storage 
or disposal at any other site or facility, except in compliance with all 
applicable laws.  To the knowledge of Procept, no other person has generated, 
used, handled, stored or disposed of any Hazardous Materials at any site 
owned or premises leased by Procept at any time or at any site in which 
Procept presently holds a mortgage or similar interest, nor has there been or 
is there threatened any release of any Hazardous Materials on or at any such 
site or premises.  Procept does not presently operate or lease nor has it 
operated or leased any site on which, underground storage tanks are or were 
located and which tanks are the responsibility of Procept to operate.  To the 
knowledge of Procept, without investigation, no lien has been imposed by any 
governmental agency in connection with the presence of any Hazardous 
Materials on any property, facility, machinery, or equipment operated or 
leased by Procept or in which Procept holds any mortgage, lien, or similar 
interest.  For purposes of this Section 2.24, "HAZARDOUS MATERIALS" shall 
mean and include any "HAZARDOUS WASTE" as defined in either the United States 
Resource Conservation and Recovery Act, 42 U.S.C. 6901, or regulations 
adopted pursuant to said Act, and also any "HAZARDOUS SUBSTANCES" or 
"HAZARDOUS MATERIALS" as defined in the United States Comprehensive 
Environmental Response, Compensation and Liability Act, 42 U.S.C. 9601, but 
excludes ordinary and customary materials in quantities reasonably required 
to be used by Procept in the ordinary course of Procept's business.

       4.25   FULL DISCLOSURE.  All documents and other papers delivered by 
or on behalf of Procept in connection with this Agreement and the 
transactions contemplated hereby are true, complete and authentic.  No 
representation, warranty or statement of Procept made in this Agreement or in 
any Exhibit or the PROCEPT DISCLOSURE SCHEDULE hereto or in any document, 
statement or certificate furnished to Procept pursuant to this Agreement 
contains any untrue statement of a material fact or omits to state a material 
fact required to be stated therein or necessary to make the statements made, 
in light of the circumstance under which they were made, not false or 
misleading.

                        SECTION 5 - COVENANTS AND AGREEMENTS

       The parties covenant and agree as follows:

       5.1    CONDUCT OF PACIFIC BUSINESS.  Except with the prior written 
consent of Procept and except as otherwise contemplated herein, during the 
period from the date hereof to the Closing Date, Pacific shall observe the 
following covenants:

              (a)    AFFIRMATIVE COVENANTS PENDING CLOSING.  Pacific and its 
Subsidiaries will:

                            (i)    PRESERVATION OF PERSONNEL.  Use all 
reasonable efforts to preserve intact their business organizations and keep 
available the services of present employees, in each case in accordance with 
past practice, it being understood that termination of employees with poor 
performance ratings shall not constitute a violation of this covenant;

                                       30
<PAGE>

                            (ii)   INSURANCE.  Use all reasonable efforts to 
keep in effect casualty, public liability, worker's compensation and other 
insurance policies in coverage amounts not less than those in effect at the 
date of this Agreement;

                            (iii)  PRESERVATION OF THE BUSINESS; MAINTENANCE 
OF PROPERTIES, CONTRACTS.  Use all reasonable efforts to preserve their 
businesses, advertise, promote and market their services, keep their 
properties intact, preserve their goodwill, and maintain all physical 
properties in good operating condition;

                            (iv)   INTELLECTUAL PROPERTY RIGHTS.  Use all 
reasonable efforts to preserve and protect Pacific's Proprietary Rights; and

                            (v)    ORDINARY COURSE OF BUSINESS.  Operate 
their businesses diligently and solely in the ordinary course.

              (b)    NEGATIVE COVENANTS PENDING CLOSING.  Pacific and its 
Subsidiaries will not:

                            (i)    DISPOSITION OF ASSETS.  Sell or transfer, 
or mortgage, pledge or create or permit to be created any encumbrance on, any 
of their assets, other than sales or transfers in the ordinary course of 
business and liens existing under arrangements disclosed herein or permitted 
under Section 3.18;

                            (ii)   LIABILITIES.  Without the consent of 
Procept, (A) incur any obligation or liability other than in the ordinary 
course of their business (provided that Pacific may incur expenses in 
connection with this transaction of up to $100,000), (B) incur any 
indebtedness for borrowed money or enter into any contracts or commitments 
involving payments by Pacific or a Subsidiary of $5,000 or more, other than 
purchase orders or commitments for inventory materials and supplies in the 
ordinary course of business;

                            (iii)  COMPENSATION.  Without the consent of 
Procept, (A) change the compensation or fringe benefits of any officer, 
director or employee, or (B) enter into or modify any Plan or any employment, 
severance or other agreement with any officer, director or employee of 
Pacific or any Subsidiary other than changes required by law to maintain the 
tax-qualified status of any Plan or as otherwise required by law;

                            (iv)   CAPITAL STOCK.  (A) Grant or accelerate 
the exercisability of, any option, warrant or other right to purchase, or to 
convert any obligation into, shares of its capital stock, (B) declare or pay 
any dividend or other distribution with respect to any shares of its capital 
stock or (C) issue any shares of its capital stock, except upon the exercise 
of options outstanding on the date hereof or as contemplated by the PACIFIC 
DISCLOSURE SCHEDULE;

                            (v)    CHARTER AND BYLAWS.  Amend the Charter or 
Bylaws of Pacific or any Subsidiary;

                            (vi)   ACQUISITIONS.  Make any material 
acquisition of property other than in the ordinary course of Pacific's or the 
Subsidiaries' business; or

                                       31
<PAGE>

                            (vii)  MATERIAL AGREEMENTS.  Without the consent 
of Procept, enter into or modify any material agreement with any other person 
or entity (other than agreements in the ordinary course of its business 
involving payments by Pacific of less than $5,000).

       5.2    CONDUCT OF PROCEPT BUSINESS.  Except with the prior written 
consent of Pacific and except as otherwise contemplated herein, during the 
period from the date hereof to the Closing Date, Procept shall observe the 
following covenants:

              (a)    AFFIRMATIVE COVENANTS PENDING CLOSING.  Procept will:

                            (i)    PRESERVATION OF PERSONNEL.  Use all 
reasonable efforts to preserve intact their business organizations and keep 
available the services of present employees, in each case in accordance with 
past practice, it being understood that termination of employees with poor 
performance ratings shall not constitute a violation of this covenant;

                            (ii)   INSURANCE.  Use all reasonable efforts to 
keep in effect casualty, public liability, worker's compensation and other 
insurance policies in coverage amounts not less than those in effect at the 
date of this Agreement;

                            (iii)  PRESERVATION OF THE BUSINESS; MAINTENANCE 
OF PROPERTIES, CONTRACTS.  Use all reasonable efforts to preserve their 
businesses, advertise, promote and market their services, keep their 
properties intact, preserve their goodwill, and maintain all physical 
properties in good operating condition;

                            (iv)   INTELLECTUAL PROPERTY RIGHTS.  Use all 
reasonable efforts to preserve and protect Procept's Proprietary Rights; and

                            (v)    ORDINARY COURSE OF BUSINESS.  Operate 
their businesses diligently and solely in the ordinary course.

              (b)    NEGATIVE COVENANTS PENDING CLOSING.  Procept will not:

                            (i)    DISPOSITION OF ASSETS.  Sell or transfer, 
or mortgage, pledge or create or permit to be created any Encumbrance on, any 
of their assets, other than sales or transfers in the ordinary course of 
business and liens existing under arrangements disclosed herein or of the 
type permitted under Section 4.18 and disclosed in the Procept 10-K;

                            (ii)   LIABILITIES.  Except as disclosed to 
Pacific herein, incur any obligation or liability other than in the ordinary 
course of Procept's business;

                            (iii)  COMPENSATION.  (A) Change the compensation 
or fringe benefits of any officer, director or employee, or (B) enter into or 
modify any Plan or any employment, severance or other agreement with any 
officer, director or employee of Procept other than changes required by law 
to maintain the tax-qualified status of any Plan or as otherwise required by 
law; or

                                       32
<PAGE>

                            (iv)   CHARTER AND BYLAWS.  Amend the Charter or 
Bylaws of Procept. 

                            (v)    ACQUISITIONS.  Make any material 
acquisition of property other than in the ordinary course of Procept's 
business; or

                            (vi)   MATERIAL AGREEMENTS.  Without the consent 
of Pacific, enter into or modify any material agreement with any other person 
or entity, other than in the ordinary course of its business.

       5.3    NASDAQ LISTING.  Procept shall take such actions as may be 
necessary to cause the shares of Procept Common Stock to be issued hereunder 
to be approved for quotation on the Nasdaq Small-Cap Market.

       5.4    AGREEMENT NOT TO ENTERTAIN OTHER OFFERS.  

              (a)    In consideration of the efforts and expenses undertaken 
by both parties in pursuing the Merger and other valuable consideration, the 
receipt and adequacy of which are acknowledged, Procept and Pacific agree 
that until the Closing Date or until this Agreement is otherwise terminated 
pursuant to Section 9, neither Procept nor Pacific nor any of their 
authorized representatives shall:

                            (i)    directly or indirectly, solicit any 
proposal relating to the acquisition by another party of all or any portion 
of the capital stock of such company or substantially all of the assets of 
such company (whether by merger or otherwise);

                            (ii)   directly or indirectly, engage in any 
discussions or negotiations with any other party regarding any such 
acquisition, or otherwise encourage or facilitate any efforts by any other 
party to engage in such an acquisition; or

                            (iii)  sell, transfer or dispose of all or any 
portion of the capital stock of such company or substantially all of the 
assets of such company (whether by merger or otherwise);

PROVIDED, HOWEVER, that nothing in the foregoing shall restrict either 
company from engaging in discussions with potential collaborative partners, 
subject to such company disclosing to the other the identity of the party 
involved in such discussions and the general nature thereof; and PROVIDED 
FURTHER that, notwithstanding the foregoing, each such company and its 
authorized representatives may participate in discussions or negotiations 
with, provide information to, and consummate a transaction with, a third 
party which would otherwise be prohibited by this section, if (A) such 
discussions or negotiations had been commenced prior to the date hereof or if 
commenced after the date hereof, were not solicited by or on behalf of such 
company and (B) such discussions or negotiations were being continued or 
initiated after consultation with and based upon written advice of 
independent legal counsel which determined in good faith that such action is 
necessary for the Board of Directors of the involved company to comply with 
its fiduciary duties to its stockholders under applicable law.

                                       33
<PAGE>

              (b)    In the event that either Pacific or Procept breaches its 
obligations under Section 5.4 or engages in discussions or negotiations with, 
provides information to, or consummates a transaction with a third party, 
which activity would have been a breach of Section 5.4 but for the second 
proviso of such section, then, unless the Merger subsequently occurs prior to 
June 30, 1999, on the earlier of (i) the consummation of any such transaction 
with a third party or (ii) June 30, 1999, such company shall pay the other a 
termination fee in the amount of $150,000, in immediately available funds to 
an account designated by the recipient party.  The parties acknowledge and 
agree that the provisions for payment of such a termination fee are included 
herein in order to induce each party to enter into this Agreement and to 
reimburse the non-terminating party for incurring the costs and expenses 
related to the contemplated Merger.  No more than one termination fee shall 
be paid by any party hereunder.  The parties hereto agree that any 
termination fee that is paid or due hereunder shall be deemed to be 
liquidated damages designed to reasonably compensate the recipient party for 
the loss incurred by the terminating party's actions.

       5.5    CORPORATE EXAMINATIONS AND INVESTIGATIONS.  Prior to the 
Effective Time, each of Procept and Pacific shall be entitled, through its 
employees and representatives, to have such access to the assets, properties, 
business, books, records and operations of the other as Procept or Pacific, 
as the case may be, shall reasonably request in connection with such party's 
investigation of the other with respect to the transaction contemplated 
hereby.  Any such investigation and examination shall be conducted at 
reasonable times and the party being investigated shall cooperate fully 
therein.  No investigation by a party shall diminish or obviate any of the 
representations, warranties, covenants or agreements of any other party 
contained in this Agreement, provided that any party having actual knowledge 
prior to the date hereof of an inaccuracy in a representation or warranty of 
another party must have given notice thereof to such other party prior to the 
date hereof to be entitled to make any recovery hereunder for breach of such 
representation or warranty.  For the purposes of this Agreement, actual 
knowledge shall mean the conscious knowledge of the executive officers of a 
party who have given substantive attention to this transaction.  In order 
that each of Procept and Pacific may have full opportunity to make such 
investigation, the party being investigated shall furnish the representatives 
of the other during such period with all such information and copies of such 
documents concerning the affairs of the party being investigated as such 
representatives may reasonably request and cause its officers, employees, 
consultants, agents, accountants and attorneys to cooperate fully with such 
representatives in connection with such investigation.

       5.6    EXPENSES.  Subject to Section 5.4, if the Merger is not 
consummated, each of Pacific and Procept shall bear its respective expenses 
incurred in connection with this Agreement and the transactions contemplated 
hereby.  Pacific represents and warrants that its good faith estimate of the 
fees and expenses of its legal counsel, financial advisors and accountants to 
be incurred in connection with this transaction are as set forth on the 
PACIFIC DISCLOSURE SCHEDULE.  If the Merger is consummated, the Surviving 
Corporation, as the successor to Pacific, shall be liable for all unpaid 
expenses of Pacific.

       5.7    AUTHORIZATION FROM OTHERS.  Prior to the Closing Date, the 
parties shall use all reasonable efforts to obtain all authorizations, 
consents and permits required to permit the consummation of the transactions 
contemplated by this Agreement, including without limitation all consents 
required from third parties who have contractual relationships with Pacific.

                                       34

<PAGE>

       5.8    CONSUMMATION OF AGREEMENT.  Each party shall use all reasonable
efforts to perform and fulfill all conditions and obligations to be performed
and fulfilled by it under this Agreement and to ensure that to the extent within
its control or capable of influence by it, no breach of any of the respective
representations, warranties and agreements hereunder occurs or exists on or
prior to the Effective Time, all to the end that the transactions contemplated
by this Agreement shall be fully carried out in a timely fashion.

       5.9    FURTHER ASSURANCES.  Each of the parties shall execute such
documents, further instruments of transfer and assignment and other papers and
take such further actions as may be reasonably required or desirable to carry
out the provisions hereof and the transactions contemplated hereby.

       5.10   SECURITIES LAW MATTERS.  Procept shall prepare and file with the
SEC a Registration Statement on Form S-4 (or any other such form required by the
SEC) (the "Registration Statement") covering the shares of Procept Common Stock
comprising the Merger Consideration as soon as practicable following the date
hereof and will use all reasonable efforts to have such Registration Statement
filed within 45 days after the date hereof and declared and maintained
effective, as soon as practicable following such filing.  Pacific will cooperate
with Procept in such preparation and, after such Registration Statement is
effective, Procept and Pacific shall facilitate the distribution of the proxy
statement and prospectus (the "Proxy Statement") contained in the Registration
Statement to the stockholders of Procept and the stockholders of Pacific.  Prior
to the Effective Time, Procept shall use all reasonable efforts to qualify the
shares of Procept Common Stock to be issued in the Merger under the securities
or "blue sky" laws of every state necessary to offer and issue the Merger
Consideration to the stockholders at the Closing, except any such state with
respect to which counsel for Procept has determined that such qualification is
not required under the securities or "blue sky" laws of such state, and except
that in no event shall Procept be obligated to qualify as a foreign corporation
or to execute a general consent to service of process in any state in which it
has not previously so qualified or has not previously so consented.

       5.11   PACIFIC STOCKHOLDER MEETING.  Pacific, acting through its Board of
Directors, shall, in accordance with applicable law and its certificate of
incorporation and by laws:

                            (i)    at a special meeting of stockholders of
Pacific and at any adjournment thereof, submit to the stockholders a proposal to
consider and act on this Agreement to obtain such approval required under the
DGCL for the consummation of the transactions contemplated hereby;

                            (ii)   subject to the duties of the Board of
Directors under applicable law as advised in writing by independent legal
counsel, include in the Proxy Statement to be delivered to the stockholders of
Pacific soliciting their approval of the transactions contemplated hereby the
recommendation of its Board of Directors that the stockholders vote in favor of
the adoption of this Agreement; and

                            (iii)  use all reasonable efforts (A) to obtain and
furnish the information required to be included by it in the Proxy Statement,
(B) to cause the Proxy Statement to be mailed to its stockholders at the
earliest practicable time after the effectiveness 


                                35

<PAGE>

of the Registration Statement, and (C) to obtain the necessary approvals by 
its stockholders of the transactions contemplated hereby.

       5.12   PROCEPT STOCKHOLDER MEETING.  Procept, acting through its Board of
Directors, shall, in accordance with applicable law and its certificate of
incorporation and bylaws:

                            (i)    at a special meeting of stockholders of
Procept and at any adjournment thereof, submit to the stockholders a proposal to
consider and act on this Agreement to obtain such approval required pursuant to
the Nasdaq Market Rules;

                            (ii)   subject to the duties of the Board of
Directors under applicable law as advised in writing by independent legal
counsel, include in the Proxy Statement to be delivered to the stockholders of
Procept soliciting their approval of this Agreement and the transactions
contemplated hereby the recommendation of its Board of Directors that the
stockholders vote in favor of such transactions; and

                            (iii)  use all reasonable efforts (A) to obtain and
furnish the information required to be included by it in the Proxy Statement,
(B) to cause the Proxy Statement to be mailed to its stockholders at the
earliest practicable time after the effectiveness of the Registration Statement,
and (C) to obtain the necessary approvals by its stockholders of this Agreement,
the Merger and the transactions contemplated hereby.

       5.13   PUBLIC ANNOUNCEMENTS AND CONFIDENTIALITY.  Any press release or
other information to the press or any third party with respect to this Agreement
or the transactions contemplated hereby shall require the prior approval of
Procept and Pacific, which approval shall not be unreasonably withheld, provided
that a party shall not be prevented from making such disclosure as it shall be
advised by counsel is required by law.  Pacific shall also keep confidential and
shall not use in any manner any information or documents obtained from Procept
or its representatives concerning Procept's assets, properties, business and
operations, unless readily ascertainable from public information, already known
or subsequently developed by Pacific independently, received from a third party
not under an obligation to keep such information confidential or otherwise
required by law.  If this Agreement terminates prior to the Closing, Procept
shall also keep confidential and shall not use in any manner any information or
documents obtained from Pacific or their representatives unless readily
ascertainable from public information, already known or subsequently developed
by Procept independently, received from a third party not under an obligation to
keep such information confidential or otherwise required by law.   If this
Agreement terminates prior to the Closing all copies of any documents obtained
from another party or its representatives will be returned, except that one copy
thereof may be retained by counsel to the party returning such documents in
order to evidence compliance hereunder.  The obligations set forth in the
previous three sentences of this Section 4.14 shall survive termination of this
Agreement.

       5.14   AFFILIATE LETTERS.  Prior to the Closing Date, Pacific shall
identify to Procept all persons who, at the time of the vote of Pacific's
stockholders on the Merger, Pacific believes may be "affiliates" of Pacific
within the meaning of Rule 145 under the Securities Act.  Pacific shall use all
reasonable efforts to provide Procept with such information as Procept shall
reasonably request for purposes of making its own determination of persons who
may be deemed 

                                 36

<PAGE>


to be affiliates of Pacific.  Pacific shall use all reasonable efforts to 
deliver to Procept prior to the Closing Date a letter from each of the 
affiliates specified by Procept in substantially the form exchanged by the 
parties (an "Affiliate Letter") and each stockholder who is identified as an 
affiliate by Pacific and Procept has delivered, or agrees to deliver to 
Procept prior to the Closing Date, an Affiliate Letter.  To the extent any 
stockholder is so identified as an affiliate, such stockholder agrees to 
deliver an Affiliate Letter at or prior to the Closing Date.

       5.15   PROCEPT SEC FILINGS.  Until the Closing Date, Procept shall
furnish Pacific with a copy of each periodic or current report filed by Procept
under the Exchange Act promptly after filing the same.  All filings made by
Procept after the date hereof pursuant to the Exchange Act will be made in a
timely fashion, will comply as to form in all material respects with the
applicable provisions of the Exchange Act and the rules and regulations
thereunder and will not contain any untrue statement of a material fact or omit
to state a material fact required to be stated therein or necessary to make the
statements therein, in light of the circumstances under which they are made, not
misleading.

       5.16   PACIFIC SEC FILINGS.  Until the Closing Date, Pacific shall
furnish Procept with a copy of each periodic or current report filed by Pacific
under the Exchange Act promptly after filing the same.  All filings made by
Pacific after the date hereof pursuant to the Exchange Act will be made in a
timely fashion, will comply as to form in all material respects with the
applicable provisions of the Exchange Act and the rules and regulations
thereunder and will not contain any untrue statement of a material fact or omit
to state a material fact required to be stated therein or necessary to make the
statements therein, in light of the circumstances under which they are made, not
misleading.

       5.17   FAIRNESS OPINIONS.  Each of Procept and Pacific shall use all
reasonable efforts to obtain a fairness opinion from the independent financial
advisers named in Sections 6.5 and 6.6 addressed to such company's Board of
Directors stating that the Merger is fair from a financial point of view to such
company and its stockholders.

       5.18   STOCK OPTIONS AND WARRANTS.

              (a)    At the Effective Time, Procept will assume the obligations
of Pacific under the outstanding options to purchase Pacific Common Stock (the
"Pacific Stock Option") set forth on the PACIFIC DISCLOSURE SCHEDULE pursuant to
Section 3 whether vested or unvested, as contemplated by the agreements
representing the Pacific Stock Options.  Each such Pacific Stock Option shall be
deemed to constitute an option granted under Procept's 1998 Equity Incentive
Plan, which amended and restated its 1989 Stock Plan (the "Procept Plan") to
acquire, on the same terms and conditions as were applicable under such Pacific
Stock Option prior to the Effective Time to the extent not in violation of the
Procept Plan that number of whole shares of Procept Common Stock equal to the
product of the number of shares of Pacific Common Stock covered by such Pacific
Stock Option immediately prior to the Effective Time multiplied by the
Conversion Factor (the "New Options"), provided that following such assumption
and adjustment, (A) all references in the New Options to Pacific shall (unless
the context otherwise requires) be deemed to be references to Procept and (B)
the exercise price per share of shares of Procept Common Stock under each New
Option shall be equal to the exercise price per share of 


                               37

<PAGE>

Pacific Common Stock under such Pacific Stock Option immediately prior to the 
Effective Time divided by the Conversion Factor (rounded down to the nearest 
cent).

       As soon as practicable after the Effective Time, Procept shall deliver to
each holder of an outstanding Pacific Stock Option an appropriate notice setting
forth such holder's rights pursuant to the New Options, and such New Option
shall continue in effect on the same terms and conditions (including
antidilution provisions) of the Pacific Stock Options, except to the extent in
violation of the Procept Plan.  

       Procept shall take all corporate action necessary to reserve for issuance
a sufficient number of shares of Procept Common Stock under the Procept Plan for
delivery pursuant to the terms set forth in this Section 5.18.

       Subject to any applicable limitations under the Securities Act, at the
Effective Time, the shares issuable under the New Options shall be subject to an
effective Registration Statement on Form S-8 (or any successor form).  Procept
shall use its reasonable best efforts to maintain the effectiveness of such
registration statement (and maintain the current status of the prospectus
relating thereto) for so long as any New Options shall remain outstanding.

              (b)    At the Effective Time, Procept will assume the obligations
of Pacific with respect to each outstanding warrant to subscribe for and
purchase Pacific Common Stock set forth on the PACIFIC DISCLOSURE SCHEDULE
pursuant to Section 3.2 (collectively, the "Pacific Warrants").  The Pacific
Warrants shall continue to have, and be subject to, the same terms and
conditions as set forth in the applicable warrant agreements and warrant
certificates, as in effect on the date of this Agreement, pursuant to which the
Pacific Warrants were issued (true and correct copies of which have been
delivered to Procept), provided that (i) all references in the Pacific Warrants
to Pacific shall (unless the context otherwise requires) be deemed to be
references to Procept, (ii) each Pacific Warrants shall be exercisable for (X)
that number of whole shares of Procept Common Stock equal to the product of the
number of shares of Pacific Common Stock covered by the Pacific Warrant
immediately prior to the Effective Time multiplied by the Conversion Factor and
(iii) the exercise price per share of shares of Procept Common Stock under each
Pacific Warrant shall be equal to the exercise price per share of Pacific Common
Stock under the Pacific Warrant  immediately prior to the Effective Time divided
by the Conversion Factor (rounded down to the nearest cent).  Procept shall (A)
reserve for issuance the number of shares of Procept Common Stock and Procept
Warrants that will become issuable upon the exercise of the Pacific Warrants
pursuant to this Section 5.18(b), and (B) promptly after the Effective Time
issue to each holder of an outstanding Pacific Warrant a document evidencing the
assumption by Procept of Pacific's obligations with respect thereto under this
Section 5.18(b).  To the extent required by the terms of the Pacific Warrants
and subject to the applicable limitations under the Securities Act, Procept
shall file a Registration Statement on the appropriate form prescribed by the
SEC covering the offering and sale to the holders of the Pacific Warrants of the
shares of Procept Common Stock purchasable upon exercise thereof, (the "Warrants
Shelf").  Procept shall use its reasonable best efforts to file the Warrants
Shelf within 60 days after the Effective Time and to cause the SEC to declare
such registration statement effective and to maintain the effectiveness of the
Warrants Shelf (and maintain the current status of the prospectus included
therein) until all Pacific Warrants have been exercised or have been terminated
in accordance with their terms.


                                    38

<PAGE>

       5.19   INDEMNIFICATION, DIRECTORS AND OFFICER'S INSURANCE.

              (a)    The Surviving Corporation's Certificate of Incorporation
and By-Laws contain provisions with respect to indemnification (the
"Indemnification Provisions"), which provisions shall not be amended, repealed
or otherwise modified for a period of six years from the Effective Time in any
manner that would adversely affect the rights thereunder of individuals who at
or before the Effective Time were directors, officers, employees, subject to
Section 5.19(d),  or agents of Pacific (the "Pacific Indemnities"), unless such
modification is required by law and provided that (i) a merger of the Surviving
Corporation into Procept or (ii) the liquidation of the Surviving Corporation
shall not be deemed a violation of this Section 5.19.

              (b)    By virtue of the Merger the Surviving Corporation shall
assume all obligations of Pacific under the Indemnification Provisions,
including such indemnification obligations (i) arising out of or pertaining to
the transactions contemplated by this Agreement or (ii) otherwise with respect
to any acts or omissions occurring at or prior to the Effective Time.

              (c)    At or prior to the Effective Time, Pacific or Procept shall
purchase or keep in effect directors' and officers' liability insurance coverage
for Pacific's directors and officers in a form reasonably acceptable to Pacific
which shall provide such directors and officers with so-called "tail" or other
coverage sufficient to ensure the Indemnification Provisions in an amount of at
least $5,000,000.

              (d)    In the event that the Surviving Corporation or any of its
successors or assigns (i) consolidates with or merges into any other person or
entity and shall not be the continuing or surviving corporation or entity of
such consolidation or merger or (ii) transfers or conveys all or substantially
all of its assets to any person or entity, then, and in each such case, proper
provision shall be made so that the successors and assigns assume the
obligations set forth in this Section 5.19.

              SECTION 6 -   CONDITIONS PRECEDENT TO THE OBLIGATIONS
                     OF EACH PARTY TO CONSUMMATE THE MERGER

       The respective obligations of each party to consummate the Merger shall
be subject to the satisfaction or waiver, at or before the Effective Time, of
each of the following conditions:

       6.1    APPROVALS.  The holders of Pacific Preferred Stock shall have
approved an amendment to the Certificate of Designation relating to all
outstanding Pacific Preferred Stock in a manner necessary to preclude the Merger
from triggering any obligation of Pacific or Procept to pay a liquidation
preference to the holders of Pacific Preferred Stock, and such amendment to the
holders of Pacific Preferred Stock, and such amendment to the Certificate of
Designation shall have been filed with the Secretary of State of Delaware.  All
required approvals of the stockholders of Pacific and Procept and all consents
and approvals referred to in Sections 3.12 and 4.12 of this Agreement, other
than those which, the failure to obtain would not affect the validity of this
transaction or materially adversely affect the business of the Surviving
Corporation after the Effective Time shall have been obtained; PROVIDED,
HOWEVER, that if Procept waives the obtaining of any consent from a contracting
party set forth in Sections 3.12 or 4.12 of 


                                     39

<PAGE>

the PACIFIC DISCLOSURE SCHEDULE, such consent shall not be a condition to 
Pacific's obligation to consummate the Merger.

       6.2    ABSENCE OF ORDER. No restraining order or injunction of any court
which prevents consummation of the Merger shall be in effect.

       6.3    NASDAQ STOCK EXCHANGE LISTING.  The shares of Procept Common Stock
to be issued in the Merger shall have been approved for quotation on the Nasdaq
Small-Cap Market.

       6.4    EFFECTIVENESS OF REGISTRATION STATEMENT  The Registration
Statement shall have been declared effective by the SEC and there shall not be
any stop order in effect with respect to the Registration Statement.

       6.5    PROCEPT FAIRNESS OPINION.  The Board of Directors of Procept shall
have received the opinion of Oscar Gruss & Son Incorporated to the effect that
the merger is fair from a financial point of view to Procept and its
stockholders and such opinion shall not have been withdrawn as of the Closing
Date.

       6.6    PACIFIC FAIRNESS OPINION.  The Board of Directors of Pacific shall
have received the opinion of Josephthal & Co. Inc. to the effect that the Merger
is fair from a financial point of view to Pacific and its stockholders and such
opinion shall not have been withdrawn as of the Closing Date.

             SECTION 7 -   CONDITIONS PRECEDENT TO THE OBLIGATION OF
                       PROCEPT TO CONSUMMATE THE MERGER

       The obligation of Procept to consummate the Merger is subject to the
satisfaction or waiver by Procept, at or before the Effective Time, of the
following conditions:

       7.1    REPRESENTATIONS, WARRANTIES AND COVENANTS.  The representations
and warranties of Pacific contained in this Agreement shall be true and correct
in all material respects on and as of the Effective Time with the same force and
effect as though made on and as of the Effective Time (with such exceptions as
may be permitted under or contemplated by this Agreement, the PACIFIC DISCLOSURE
SCHEDULE).  Pacific shall have performed and complied in all material respects
with all covenants and agreements required by this Agreement to be performed or
complied with by them on or prior to the Effective Time.  Pacific shall have
delivered to Procept a certificate, dated the Closing Date, to the foregoing
effect, as applicable.

       7.2    CERTIFICATE OF SECRETARY OF PACIFIC.  Pacific shall have delivered
to Procept a certificate of the Secretary of Pacific dated as of the Closing
Date, certifying as to (i) the Articles of Incorporation and the Bylaws of
Pacific, (ii) the resolutions of the Board of Directors of Pacific authorizing
and approving the execution, delivery and performance by Pacific of this
Agreement and the transactions contemplated hereby and (iii) the resolutions of
the stockholders of Pacific authorizing and approving this Agreement and the
transactions contemplated hereby.

       7.3    AFFILIATE LETTERS.  Procept shall have received the Affiliate
Letters referred to in Section 5.15.


                                    40

<PAGE>

       7.4    OPINION OF COUNSEL TO PACIFIC.  Procept shall have received an
opinion of Patterson, Belknap, Webb and Tyler LLP, counsel to Pacific, dated the
Closing Date and in form and substance reasonably acceptable to Procept.  

       7.5    MERGER CERTIFICATE.  Pacific shall have executed and delivered the
Merger Certificate referred to in Section 1.2.

       7.6    BTI MERGER AGREEMENT.  The acquisition of Binary Therapeutics,
Inc. ("BTI") by Pacific (the "BTI Merger") shall have been consummated by the
issuance of Pacific Common Stock as contemplated by the Agreement and Plan of
Merger dated as of June 4, 1996, as amended.  

       7.7    AGREEMENT WITH LENDERS.  Each of Lindsay Rosenwald, the Aries
Trust and the Aries Domestic Fund, L.P. (the "Aries Funds"), as holders of
promissory notes payable by BTI in the aggregate principal amount of $443,000,
(the "Pacific Notes"), shall have entered into an agreement with Pacific and
Procept, to Procept's reasonable satisfaction, providing for the conversion of
all outstanding principal and interest of indebtedness represented by demand
notes issued by BTI to Lindsay Rosenwald in the aggregate face amount of
$143,000 and by Senior Bridge Notes issued by BTI to the Aries Funds in the
aggregate face amount of $100,000, into shares of Procept Common Stock at the
rate of $5.00 per share, provided (i) such shares of Common Stock shall be
entitled to contractual rights substantially the same as those set forth in
Section 10 of this Agreement and (ii) Procept or Pacific shall have paid each of
Lindsay Rosenwald and the Aries Funds $100,000 to cancel such indebtedness in
full.

       7.8    APPROVALS.  Pacific shall have received approval of their
stockholders and all other approvals, clearances and consents from any
governmental entities and other third parties necessary or desirable for the
consummation of the Merger and the Pacific shares shall be free and clear of any
liens or encumbrances.

       7.9    DISSENTING SHARES.  The Dissenting Shares of Common Stock shall
not exceed five percent (5%) of the shares of the Pacific Common Stock issued
and outstanding or issuable on the Closing Date.  

       7.10   BANK ACCOUNTS.  Pacific shall have delivered to Procept
documentation necessary to change the authorized signatories for Pacific's bank
and brokerage accounts as specified by Procept.

       7.11   CERTIFICATES.  Pacific shall have furnished Procept with such
certificates of public officials as may be reasonably requested by Procept.

  SECTION 8 - CONDITIONS PRECEDENT TO THE OBLIGATION OF PACIFIC TO 
                         CONSUMMATE THE MERGER

       The obligation of Pacific to consummate the Merger is subject to the
satisfaction or waiver by them, at or before the Effective Time, of the
following conditions:

       8.1    REPRESENTATIONS, WARRANTIES AND COVENANTS.  The representations
and warranties of Procept contained in this Agreement shall be true and correct
in all material respects on and as 


                                    41

<PAGE>

of the Effective Time with the same force and effect as though made on and as 
of the Effective Time (with such exceptions as may be permitted under or 
contemplated by this Agreement).  Procept shall have performed and complied 
in all material respects with all covenants and agreements required by this 
Agreement to be performed or complied with by it on or prior to the Effective 
Time.  Procept shall have delivered to Pacific a certificate, dated the 
Effective Time, to the foregoing effect.  

       8.2    CERTIFICATE OF SECRETARY OF PROCEPT.  Procept shall have delivered
to Pacific a certificate of the Secretary of Procept dated as of the Closing
Date, certifying as to (i) the Articles of Incorporation and the Bylaws of
Pacific, (ii) the resolutions of the Board of Directors of Procept authorizing
and approving the execution, delivery and performance by Procept of this
Agreement and the transactions contemplated hereby and (iii) the resolutions of
the stockholders of Procept authorizing and approving this Agreement and the
transactions contemplated hereby.

       8.3    CERTIFICATE OF SECRETARY OF PAC.  PAC shall have delivered to
Pacific a certificate of the Secretary of PAC dated as of the Closing Date,
certifying as to (i) the Certificate of Incorporation and the Bylaws of PAC, as
in effect on and as of the Closing Date and (ii) the resolutions of the Board of
Directors and Stockholder of PAC authorizing and approving the execution,
delivery and performance by PAC of this Agreement and the transactions
contemplated hereby.

       8.4    APPROVALS.  Procept shall have received approval of their
stockholders and all other approvals, clearances and consents from any
governmental entities and other third parties necessary or desirable for the
consummation of the Merger.

       8.5    OPINION OF COUNSEL TO PROCEPT.  Pacific shall have received an
opinion of Palmer & Dodge LLP, counsel to Procept, dated the Closing Date and in
form and substance reasonably acceptable to Pacific.

       8.6    CERTIFICATES.  Procept shall have furnished Pacific with such
certificates of public officials as may be reasonably requested by Pacific.

                SECTION 9 -   TERMINATION, AMENDMENT AND WAIVER

       9.1    TERMINATION.  This Agreement may be terminated at any time on or
prior to the Closing Date, whether prior to or after approval by Pacific's
stockholders, as follows:

              (a)    by Pacific or Procept if, without fault of the terminating
party, the Closing Date shall not have occurred on or before June 30, 1999,
which date may be extended by mutual consent of the parties;

              (b)    by Pacific upon written notice to Procept if any
representation or warranty of Procept made herein was not true and correct in
all material respects when made or Procept has materially breached any covenant
contained herein and has not cured such breach within thirty (30) business days
of receipt of written notice from Pacific or by the Closing Date, whichever
occurs first;


                                    42

<PAGE>

              (c)    by Procept upon written notice to Pacific if any
representation or warranty made herein by Pacific was not true and correct in
all material respects when made or Pacific has materially breached any covenant
contained herein and has not cured such breach within thirty (30) business days
of receipt of written notice from Procept or by the Closing Date, whichever
occurs first;

              (d)    by any party if any court of competent jurisdiction or
governmental body shall have issued an order, decree or ruling or taken any
other action restraining, enjoining or otherwise prohibiting the Merger and such
order, decree or ruling shall have become final and nonappealable;

              (e)    by either Procept or Pacific if the Procept or Pacific
stockholders vote and fail to approve the Merger as required by Delaware law;

              (f)    by Procept if Pacific's Board of Directors (i) fails to
include in the Proxy Statement its recommendation that Pacific stockholders vote
in favor of the adoption of this Agreement or (ii) withdraws its recommendation
that stockholders vote in favor (other than in connection with exercising
Pacific's rights to terminate this Agreement pursuant to subsection (b) or (d)
of this Section 9.1); 

              (g)    by Pacific if Procept's Board of Directors (i) fails to
include in the Proxy Statement its recommendation that Procept stockholders vote
in favor of the adoption of this Agreement or (ii) withdraws its recommendation
that stockholders vote in favor (other than in connection with exercising
Procept rights to terminate this Agreement pursuant to Subsection (c) or (d) of
this Section 9.1);

              (h)    at any time with the written consent of Procept and
Pacific.

       9.2    EFFECT OF TERMINATION.  If this Agreement is terminated as
provided in Section 9.1, this Agreement shall forthwith become void and have no
effect, without further obligation on the part of any party, its directors,
officers or stockholders following the date of such termination, other than the
provisions of this Section 9.2, Section 5.4 relating to a termination fee,
Section 5.6 relating to expenses and Section 5.13 relating to publicity and
confidentiality to the extent provided therein.  Nothing contained in Section
9.2 shall eliminate or reduce any party's liability to another party for any
breach of this Agreement occurring before such termination.

                      SECTION 10 - ADDITIONAL CONTRACTUAL RIGHTS

       10.1   DEFINITIONS.  As used in this Agreement, the following terms shall
have the following meanings, unless the context otherwise requires:

              10.1.1 "SECTION 10 RIGHTS" shall mean the rights to receive all
Reset Issuances, Semi-Annual Issuances, Dilution Issuances and Qualified
Offering Issuances and the right to exercise the Liquidation Put and the
Exchange Right, as provided herein.

              10.1.2 "CHANGE OF SHARES" shall mean any event that necessitates
an adjustment to the Dilution Value (as defined below) pursuant to Section 10.7
below.

                                      43

<PAGE>

              10.1.3 The "CLOSING BID PRICE" of any security, for any trading
day (as defined below), shall be the reported per share closing bid price,
regular way, of such security on the relevant Stock Market (as defined below) on
such trading day or, if there were no transactions on such trading day, the
average of the reported closing bid and asked prices, regular way, of such
security on the relevant Stock Market on such trading day.

              10.1.4  "DILUTION EVENT" shall mean any event that necessitates an
adjustment to the Dilution Value (as defined below) pursuant to Section 10.6
below.

              10.1.5 The "DILUTION VALUE" initially shall be identical to the
Dilution Value in effect immediately following the Effective Time under Article
VI of the Subscription Agreements between Procept and the purchasers in
Procept's 1998 private placement. The Dilution Value is subject to adjustment
pursuant to Sections 10.2, 10.6, 10.7 and 10.15.  The Dilution Value immediately
following the Effective Time is currently anticipated to be $3.75.

              10.1.6 "FAIR MARKET VALUE" of any asset (including any security)
means the fair market value thereof as mutually determined by Procept and the
financial advisor engaged by Procept in connection with Procept's 1998 private
placement (the "FINANCIAL ADVISOR").  If Procept and the Financial Advisor are
unable to reach agreement on any valuation matter, such valuation shall be
submitted to and determined by a nationally recognized independent investment
bank selected by the Board of Directors of Procept and the Financial Advisor
(or, if such selection cannot be agreed upon promptly, or in any event within
ten days, then such valuation shall be made by a nationally recognized
independent investment banking firm selected by the American Arbitration
Association in New York City in accordance with its rules), the costs of which
valuation shall be paid for by Procept.

              10.1.7 The "ISSUANCE BASE AMOUNT" for the Rights Holder, at any
time, means the sum of (i) the number of shares of Procept Common Stock acquired
by the Rights Holder in the Merger in respect of such Rights Holder's shares of
Pacific Preferred Stock (ii) the number of shares of any Reset Issuances (as
defined below) made to such Rights Holder occurring before such time, (iii) the
number of shares of any Semi-Annual Issuances (as defined below) made to such
Rights Holder occurring before such time, (iv) the number of shares of any
Dilution Issuances (as defined below) made to such Rights Holder occurring
before such time and (v) the number of shares of any Qualified Offering
Issuances (as defined below) made to such Rights Holder occurring before such
time (with appropriate adjustments for any Change of Shares and subject to
reduction pursuant to Section 10.10).  For any transferee Rights Holder, the
Issuance Base Amount, at any time, shall be the number of shares of Procept
Common Stock related to such Section 10 Rights as were transferred to such
Rights Holder plus the number of shares of any Reset Issuance, Semi-Annual
Issuance, Dilution Issuance and Qualified Offering Issuance made to such Rights
Holder occurring subsequent to such transfer but before such time.  The Issuance
Base Amount shall include Dilution Issuances which would have been required but
for the operation of Paragraph 10.6.2(a).

              10.1.8 "LIQUIDATION EVENT" shall mean any (i) liquidation,
dissolution or winding up of Procept, whether voluntary or involuntary, (ii)
sale or other disposition of all or substantially all of the assets of Procept
or (iii) any consolidation, merger, combination, reorganization or other
transaction in which Procept is not the surviving entity or shares of 


                              44

<PAGE>

Procept Common Stock constituting more than fifty percent (50%) of the voting 
power of Procept are exchanged for or changed into stock or securities of 
another entity, cash and/or any other property (clause (iii) of this 
Subsection being referred to as a "Merger Transaction").  Notwithstanding the 
above, any consolidation, merger, combination, reorganization or other 
transaction in which Procept is not the surviving entity but the stockholders 
of Procept immediately prior to such transaction own in excess of 50% of the 
voting power of the corporation surviving such transaction and own such 
interest in substantially the same proportions as prior to such transaction, 
shall not be considered a Liquidation Event or a Merger Transaction, provided 
that the surviving corporation has made appropriate provisions acceptable to 
the Financial Advisor to ensure that the Section 10 Rights survive any such 
transaction.

              10.1.9 "MARKET PRICE" per share of Procept Common Stock shall mean
the average Closing Bid Price (adjusted, where appropriate, for any Change of
Shares) for twenty (20) consecutive trading days, ending with the trading day
immediately prior to the date as of which the Market Price is being determined;
provided, however, that if the prices referred to in the definition of Closing
Bid Price cannot be determined on any trading day, "Market Price" shall mean the
Fair Market Value.

              10.1.10  The "POST-DILUTION COMMON QUANTITY" means the quotient of
the Pre-Dilution Common Value (as defined below) divided by the Dilution Value
immediately following the relevant Dilution Event, Reset Event or Qualified
Offering Adjustment Event (as defined below).

              10.1.11  The "PRE-DILUTION COMMON VALUE" means the product of the
Issuance Base Amount multiplied by the Dilution Value immediately preceding the
relevant Dilution Event, Reset Event or Qualified Offering Adjustment Event (as
defined below).

              10.1.12  "RIGHTS HOLDER" shall mean (i) a holder of Pacific
Preferred Stock immediately prior to the Effective Time who receives shares of
Procept Common Stock on conversion of such shares of Pacific Preferred Stock,
(ii) a holder of BTI indebtedness prior to the effective time who receives
shares of Procept Common Stock pursuant to the debt conversion contemplated by
Section 7.7 hereof or (iii) any Person who succeeds to such Rights Holder's
Section 10 Rights pursuant to Section 10.9.

              10.1.13  The "STOCK MARKET" shall mean, with respect to any
security, the principal national securities exchange on which such security is
listed or admitted to trading or, if such security is not listed or admitted to
trading on any national securities exchange, shall mean The Nasdaq National
Market System or The Nasdaq SmallCap Market (collectively, "Nasdaq") or, if such
security is not quoted on Nasdaq, shall mean the OTC Bulletin Board or, if such
security is not quoted on the OTC Bulletin Board, shall mean the 
over-the-counter market as furnished by any NASD member firm selected from 
time to time by Procept for that purpose.

              10.1.14  A "TRADING DAY" shall mean a day on which the Stock
Market is open for the transaction of business.

              10.1.15  "TRADING PRICE" shall mean the lower of (i) the average
Closing Bid Price of the Procept Common Stock for the thirty (30) consecutive
trading days immediately preceding


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<PAGE>

the date as of which the Trading Price is being determined (with appropriate 
adjustments for any Change of Shares) and (ii) the average Closing Bid Price 
of the Procept Common Stock for five (5) consecutive trading days immediately 
preceding the date as of which the Trading Price is being determined (with 
appropriate adjustments for any Change of Shares).

              10.1.16  The "TRANSFER AGENT" shall mean American Stock Transfer &
Trust Company or the duly appointed successor thereto serving as the transfer
agent for the Procept Common Stock.

       10.2   RESET.

              10.2.1 The Dilution Value in effect immediately prior to April 9,
1999 (the "RESET DATE") shall be adjusted and reset effective as of the Reset
Date if the Market Price of the Procept Common Stock as of the Reset Date (the
"12-MONTH TRADING PRICE") is less than 140% of the then applicable Dilution
Value (a "RESET EVENT").  Upon the occurrence of a Reset Event, the Dilution
Value shall be reduced to be equal to the greater of (A) the 12-Month Trading
Price divided by 1.40, and (B) 25% of the then applicable Dilution Value.

              10.2.2 Within fifteen  (15) days of the Reset Date, Procept shall
prepare a certificate signed by the Chief Executive Officer or President, and by
the Treasurer or an Assistant Treasurer or the Secretary or an Assistant
Secretary, of Procept setting forth the Dilution Value as of the Reset Date,
showing in reasonable detail the facts upon which such Dilution Value is based,
and such certificate shall forthwith be filed with the Transfer Agent.  A notice
stating that the Dilution Value has been adjusted pursuant to this paragraph, or
that no adjustment is necessary, and setting forth the Dilution Value in effect
as of the Reset Date shall be mailed as promptly as practicable after the Reset
Date by Procept to all Rights Holders at their last addresses as they shall
appear in the Transfer Agent's record books.

       10.3   RESET ISSUANCE.  If there is any change in the Dilution Value as a
result of Subsection 10.2.1, then, on such date, Procept shall issue to the
Rights Holder a number of shares of Procept Common Stock (the "RESET ISSUANCE")
equal to the difference between the Post-Dilution Common Quantity minus the
Issuance Base Amount.

       10.4   SEMI-ANNUAL ISSUANCES.  On each six month anniversary of the Reset
Date (or the next succeeding business day), Procept shall issue (each a 
"SEMI-ANNUAL ISSUANCE") to the Rights Holder a number of shares of Procept 
Common Stock equal to 5% of the Issuance Base Amount on the applicable six month
anniversary date.

       10.5   DILUTION ISSUANCES.  Upon the occurrence of any Dilution Event
after the Effective Time, Procept shall issue (each a "DILUTION ISSUANCE") to
the Rights Holder a number of shares of Procept Common Stock equal to the
difference of the Post-Dilution Common Quantity minus the Issuance Base Amount.

       10.6   ANTI-DILUTION ADJUSTMENTS.

              10.6.1 Except as otherwise provided in Subsection 10.6.3, in the
event Procept shall, at any time or from time to time after the date hereof,
sell or issue any shares of Procept Common Stock for a consideration per share
less than either (i) the Dilution Value in effect on 


                                  46

<PAGE>

the date of such sale or issuance or (ii) the Market Price of the Procept 
Common Stock as of the date of the sale or issuance (any such sale or 
issuance a "DILUTIVE ISSUANCE"), then, and thereafter upon each further 
Dilutive Issuance, the Dilution Value in effect immediately prior to such 
Dilutive Issuance shall be changed to a price (rounded to the nearest cent) 
determined by multiplying the Dilution Value in effect immediately prior 
thereto by a fraction, the numerator of which shall be the sum of the number 
of shares of Procept Common Stock outstanding immediately prior to the 
Dilutive Issuance and the number of shares of Procept Common Stock which the 
aggregate consideration received (determined as provided in Paragraph 
10.6.2(e) below) for the issuance of such additional shares would purchase at 
the greater of (x) the Dilution Value in effect on the date of such issuance 
or (y) the Market Price of the Procept Common Stock as of such date, and the 
denominator of which shall be the number of shares of Procept Common Stock 
outstanding immediately after the Dilutive Issuance.  Such adjustment shall 
be made successively whenever such an issuance is made.

              10.6.2 For purposes of Subsection 10.6, the following Paragraphs
(a) to (e) shall also be applicable:

              (a)    No adjustment of the Dilution Value shall be made unless
such adjustment would require a decrease of at least $.01; provided that any
adjustments which by reason of this Paragraph 10.6.2(a) are not required to be
made shall be carried forward and shall be made at the time of and together with
the next subsequent adjustment which, together with adjustments so carried
forward, shall require a decrease of at least $.01 in the Dilution Value then in
effect hereunder.

              (b)    In case of (A) the sale or other issuance by Procept
(including as a component of a unit) of any rights or warrants to subscribe for
or purchase, or any options for the purchase of, Procept Common Stock or any
securities convertible into or exchangeable for Procept Common Stock (such
securities convertible, exercisable or exchangeable into Procept Common Stock
being herein called "CONVERTIBLE SECURITIES"), or (B) the issuance by Procept,
without the receipt by Procept of any consideration therefor, of any rights or
warrants to subscribe for or purchase, or any options for the purchase of,
Procept Common Stock or Convertible Securities, whether or not such rights,
warrants or options, or the right to convert or exchange such Convertible
Securities, are immediately exercisable, and the consideration per share for
which Procept Common Stock is issuable upon the exercise of such rights,
warrants or options or upon the conversion or exchange of such Convertible
Securities (determined by dividing (x) the minimum aggregate consideration, as
set forth in the instrument relating thereto, without regard to any antidilution
or similar provisions contained therein for a subsequent adjustment of such
amount, payable to Procept upon the exercise of such rights, warrants or
options, plus the consideration received by Procept for the issuance or sale of
such rights, warrants or options, plus, in the case of such Convertible
Securities, the minimum aggregate amount, as set forth in the instrument
relating thereto, without regard to any antidilution or similar provisions
contained therein for a subsequent adjustment of such amount, of additional
consideration, if any, other than such Convertible Securities, payable upon the
conversion or exchange thereof, by (y) the total maximum number, as set forth in
the instrument relating thereto, without regard to any antidilution or similar
provisions contained therein for a subsequent adjustment of such amount, of
shares of Procept Common Stock issuable upon the exercise of such rights,
warrants or options or upon the conversion or exchange of such 


                                 47

<PAGE>

Convertible Securities issuable upon the exercise of such rights, warrants or 
options) is less than either the Dilution Value or the Market Price of the 
Procept Common Stock as of the date of the issuance or sale of such rights, 
warrants or options, then such total maximum number of shares of Procept 
Common Stock issuable upon the exercise of sch rights, warrants or options or 
upon the conversion or exchange of such Convertible Securities (as of the 
date of the issuance  or sale of such rights, warrants or options) shall be 
deemed to be "Procept Common Stock" for purposes of Subsection 10.6.1 and 
shall be deemed to have been sold for an amount equal to such consideration 
per share and shall cause an adjustment to be made in accordance with 
Subsection 10.6.1.

              (c)    In case of the sale or other issuance by Procept of any
Convertible Securities, whether or not the right of conversion or exchange
thereunder is immediately exercisable, and the price per share for which Procept
Common Stock is issuable upon the conversion or exchange of such Convertible
Securities (determined by dividing (x) the total amount of consideration
received by Procept for the sale of such Convertible Securities, plus the
minimum aggregate amount, as set forth in the instrument relating thereto,
without regard to any antidilution or similar provisions contained therein for a
subsequent adjustment of such amount, of additional consideration, if any, other
than such Convertible Securities, payable upon the conversion or exchange
thereof, by (y) the total maximum number, as set forth in the instrument
relating thereto without regard to any antidilution or similar provisions
contained therein for a subsequent adjustment of such amount, of shares of
Procept Common Stock issuable upon the conversion or exchange of such
Convertible Securities) is less than either the Dilution Value or the Market
Price of the Procept Common Stock as of the date of the sale or other issuance
of such Convertible Securities, then such total maximum number of shares of
Procept Common Stock issuable upon the conversion or exchange of such
Convertible Securities (as of the date of the sale of such Convertible
Securities) shall be deemed to be "Procept Common Stock" for purposes of
Subsection 10.6.1 and shall be deemed to have been sold for an amount equal to
such consideration per share and shall cause an adjustment to be made in
accordance with Subsection 10.6.1.

              (d)    In case Procept shall modify the rights of conversion,
exchange or exercise of any of the securities referred to in Paragraphs (b) or
(c) of this Subsection 10.6.2 or any other securities of Procept convertible,
exchangeable or exercisable for shares of Procept Common Stock, for any reason
other than an event that would require adjustment to prevent dilution, so that
the consideration per share received by Procept after such modification is less
than either the Dilution Value or the Market Price of the Procept Common Stock
as of the date prior to such modification, then such securities, to the extent
not theretofore exercised, converted or exchanged, shall be deemed to have
expired or terminated immediately prior to the date of such modification and
Procept shall be deemed for purposes of calculating any adjustments pursuant to
this Section 10.6 to have issued such new securities upon such new terms on the
date of modification. Such adjustment shall become effective as of the date upon
which such modification shall take effect.  On the expiration or cancellation of
any such right, warrant or option or the termination or cancellation of any such
right to convert or exchange any such Convertible Securities, the Dilution Value
then in effect hereunder shall forthwith be readjusted to such Dilution Value as
would have obtained (A) had the adjustments made upon the issuance or sale of
such rights, warrants, options or Convertible Securities been made upon the
basis of the issuance of only the number of shares of Procept Common Stock
theretofore actually 


                              48

<PAGE>

delivered (and  the total consideration received therefor) upon the exercise 
of such rights, warrants or options or upon the conversion or exchange of 
such Convertible Securities and (B) had adjustments been made on the basis of 
the Dilution Value as adjusted under clause (A) of this sentence for all 
transactions (which would have affected such adjusted Dilution Value) made 
after the issuance or sale of such rights, warrants, options or Convertible 
Securities.

              (e)    In case of the sale of any shares of Procept Common Stock,
any Convertible Securities, any rights or warrants to subscribe for or purchase,
or any options for the purchase of, Procept Common Stock or Convertible
Securities, the consideration received by Procept therefor shall be deemed to be
the gross sales price therefor without deducting therefrom any expense paid or
incurred by Procept or any underwriting discounts or commissions or concessions
paid or allowed by Procept in connection therewith.  In the event that any
securities shall be issued in connection with any other securities of Procept,
together comprising one integral transaction in which no specific consideration
is allocated among the securities, then each of such securities shall be deemed
to have been issued for such consideration as the Board of Directors of Procept
determines in good faith; provided, however that if the Financial Advisor
disagrees with such determination, Procept shall retain, at its own expense, an
independent investment banking firm acceptable to the Financial Advisor for the
purpose of obtaining an appraisal.

              10.6.3 Notwithstanding any other provision hereof, no adjustment
to the Dilution Value will be made:

              (a)    upon the exercise of any of the options outstanding on the
date hereof under Procept's existing stock option plans; or

              (b)    upon the issuance or exercise of options which may
hereafter be granted with the approval of Procept's Board of Directors, or
exercised, under any employee benefit plan of Procept to officers, directors,
consultants or employees, but only with respect to such options as are
exercisable at prices no lower than the Closing Bid Price (or, if the prices
referenced in the definition of Closing Bid Price cannot be determined, the Fair
Market Value) of the Procept Common Stock as of the date of grant thereof; or

              (c)    upon exercise of the Placement Options or the Advisory
Options (as defined in Exhibits B and C to the Securities Purchase Agreement
dated as of June 30, 1997 between Procept and certain stock purchasers), upon
the exercise of the Class C Warrants of Procept currently outstanding or
issuable pursuant to the exercise of the Placement and Advisory Options, as set
forth in the PROCEPT DISCLOSURE SCHEDULE pursuant to Section 4.2 or upon the
issuance or the conversion of any Class C Warrants approved in writing by the
Financial Advisor; or

              (d)    upon the issuance or sale of Procept Common Stock or
Convertible Securities pursuant to the exercise of any rights, options or
warrants to receive, subscribe for or purchase, or any options for the purchase
of, Procept Common Stock or Convertible Securities, whether or not such rights,
warrants or options were outstanding on the Effective Time or were thereafter
issued or sold, provided that an adjustment was either made or not required to
be made 


                                  49

<PAGE>

in accordance with Subsection 10.6.1 in connection with the issuance or
sale of such securities or any modification of the terms thereof; or

              (e)    upon the issuance or sale of Procept Common Stock upon
conversion or exchange of any Convertible Securities, provided that any
adjustments required to be made upon the issuance or sale of such Convertible
Securities or any modification of the terms thereof were so made, and whether or
not such Convertible Securities were outstanding on the Effective Time or were
thereafter issued or sold; or

              (f)    upon the issuance of stock that may hereafter be purchased
or sold with the approval of Procept's Board of Directors, under the 1993
Employee Stock Purchase Plan of Procept to officers, directors, consultants or
employees, but only with respect to such shares as are purchased and/or sold in
accordance with the current plan and at the prices no lower than eighty-five
percent (85%) of the Closing Bid Price (or, if the prices referenced in the
definition of Closing Bid Price cannot be determined, 85% of the Fair Market
Value) of the Procept Common Stock as of the date of purchase and/or sale
thereof;

       Paragraph 10.6.2(d) shall nevertheless apply to any modification of the
rights of conversion, exchange or exercise of any of the securities referred to
in this Subsection 10.6.3, except that Paragraph 10.6.2(d) shall not apply to
any modification of the rights of conversion, exchange or exercise of the
securities excepted by Paragraph (c) of this Subsection 10.6.3 that are required
by the original terms of those respective instruments.

              10.6.4 As used in this Section 10.6, the term "PROCEPT COMMON
STOCK" shall mean and include Procept's  Common Stock authorized at the
Effective Time and shall also include any capital stock of any class of Procept
thereafter authorized which shall not be limited to a fixed sum or percentage in
respect of the rights of the holders thereof to participate in dividends and in
the distribution of assets upon the voluntary liquidation, dissolution or
winding up of Procept.

              10.6.5 Procept from time to time may decrease the Dilution Value
by any amount for any period of time if the period is at least 20 days and if
the decrease is irrevocable during the period.  Whenever the Dilution Value is
so decreased, Procept shall mail to the Rights Holders a notice of the decrease
at least 15 days before the date the decreased Dilution Value takes effect, and
such notice shall state the decreased Dilution Value and the period it will be
in effect.

       Procept may make such decreases in the Dilution Value, in addition to
those required or allowed by this Section 10, as shall be determined by it, as
evidenced by a resolution of Procept's Board of Directors, to be advisable in
order to avoid or diminish any income tax to holders of Procept Common Stock
resulting from any dividend or distribution of stock or issuance of rights or
warrants to purchase or subscribe for stock or from any event treated as such
for income tax purposes.

       10.7   CHANGE OF SHARES ADJUSTMENTS.  In the event Procept shall, at any
time or from time to time after the date hereof (i) issue any shares of Procept
Common Stock as a stock dividend to the holders of Procept Common Stock or (ii)
subdivide or combine the outstanding shares of Procept Common Stock into a
greater or lesser number of shares (any such issuance, 


                                 50

<PAGE>

subdivision or combination being herein called a "CHANGE OF SHARES"), then 
the Dilution Value shall be changed to a price (rounded to the nearest cent) 
determined by multiplying the Dilution Value in effect immediately prior to 
such Change of Shares by a fraction, the numerator of which shall be the 
number of shares of Procept Common Stock outstanding immediately prior to the 
Change of Shares and the denominator of which shall be the number of shares 
of Procept Common Stock outstanding immediately following the Change of 
Shares.

       10.8   LIQUIDATION PUT.

              10.8.1 The Rights Holder may require Procept to repurchase with
cash any number (not to exceed such Rights Holder's Issuance Base Amount) of
shares of Procept Common Stock then owned by such Rights Holder for 140% of the
aggregate Dilution Value of such shares; provided, however, in the event of a
Merger Transaction, any repurchase pursuant to this Section 10.8 may be paid in
cash, property (valued as provided in Subsection 10.8.4) and/or securities
(valued as provided in Subsection 10.8.4) of the entity surviving such Merger
Transaction.

              10.8.2 The Rights Holder covenants not to exercise the Liquidation
Put unless a Liquidation Event has occurred.

              10.8.3 The Rights Holder's Section 10 Rights shall be terminated
to the pro rata extent of any exercise of such Rights Holder's Liquidation Put.

              10.8.4 Any securities or other property to be delivered to the
Rights Holder pursuant to this Section 10.8 shall be valued as follows:

              (a)    Securities not subject to an investment letter or other
similar restriction on free marketability:

                            (i)    If actively traded on the Stock Market, the
value shall be deemed to be the Market Price of such securities as of the third
day prior to the date of valuation.

                            (ii)   If not actively traded on the Stock Market,
the value shall be the Fair Market Value of such securities.

              (b)    For securities for which there is an active public market
but which are subject to an  investment letter or other restrictions on free
marketability, the value shall be the Fair Market Value thereof, determined by
discounting appropriately the Market Price thereof.

              (c)    For all other securities, the value shall be the Fair
Market Value thereof.

       10.9   TRANSFER OF RIGHTS UNDER THIS SECTION 10.  A Rights Holder's
Section 10 Rights are not transferable until after April 9, 1999.  The Rights
Holder's Section 10 Rights are not transferable unless the transferee will be
both the record and beneficial owner of the related Procept Common Stock and
executes and delivers to Procept a counterpart to this Section 10 agreeing to be
bound by the obligations of the Rights Holder hereunder.  Any such transferee
must provide his or her name and address, which name and address must be that of
the beneficial owner, to Procept.  Any transfer of Procept Common Stock and
related Section 10 Rights must 


                                 51

<PAGE>

be performed in accordance with applicable securities laws and regulations, 
and the transferor must provide Procept with an opinion of counsel, 
satisfactory to Procept, to that effect.  Furthermore, no transfer of Section 
10 Rights may be made relating to fewer shares of Procept Common Stock than 
the quotient of $25,000 divided by the Dilution Value.  ANY PURPORTED 
TRANSFER OF SECTION 10 RIGHTS NOT IN COMPLIANCE WITH THIS SECTION 10.9 SHALL 
BE NULL AND VOID AND THE RIGHTS HOLDER SHALL FORFEIT ALL SECTION 10 RIGHTS 
RELATED TO SUCH TRANSFERRED PROCEPT COMMON STOCK.  Upon, and to the extent 
of, any transfer of Procept Common Stock without the related Section 10 
Rights, such related Section 10 Rights shall terminate.

       10.10  ADJUSTMENTS TO ISSUANCE BASE AMOUNT.  Upon the termination of any
of the Rights Holder's Section 10 Rights, such Rights Holder's Issuance Base
Amount shall be proportionally reduced.

       10.11  NOTICES. 

              10.11.1  After each adjustment of the Dilution Value pursuant 
to Sections 10.2, 10.6, 10.7 and 10.15 Procept will promptly prepare a 
certificate signed by the Chief Executive Officer or President, and by the 
Treasurer or an Assistant Treasurer or the Secretary or an Assistant 
Secretary, of Procept setting forth:  (i) the Dilution Value as so adjusted 
and (ii) a brief statement of the facts accounting for such adjustment.  
Procept will promptly file such certificate with the Transfer Agent and cause 
a brief summary thereof to be sent by ordinary first class mail to each 
Rights Holder at his or her last address as it shall appear on the Transfer 
Agent's record books.  No failure to mail such notice nor any defect therein 
or in the mailing thereof shall affect the validity of such adjustment.  The 
affidavit of an officer of the Transfer Agent or the Secretary or an 
Assistant Secretary of Procept that such notice has been mailed shall, in the 
absence of fraud, be prima facie evidence of the facts therein stated.  The 
Transfer Agent may rely on the information in the certificate as true and 
correct and has no duty nor obligation independently to verify the amounts or 
calculations therein set forth.

              10.11.2  After any adjustment in the Issuance Base Amount
resulting from (i) any Reset Issuances, Semi-Annual Issuances, Dilution
Issuances or Qualified Offering Issuance (ii) any Change in Shares or (iii) any
termination of Section 10 Rights, Procept will promptly prepare a certificate
signed by the Chief Executive Officer or President, and by the Treasurer or an
Assistant Treasurer or the Secretary or an Assistant Secretary, of Procept
setting forth:  (x) the Issuance Base Amount immediately preceding and
succeeding such adjustment and (y) a brief statement of the facts accounting for
such adjustment.  Procept will promptly file such certificate with the Transfer
Agent and cause a brief summary thereof to be sent by ordinary first class mail
to each Rights Holder at his or her last address as it shall appear on the
Transfer Agent's record books.  No failure to mail such notice nor any defect
therein or in the mailing thereof shall affect the validity of such adjustment. 
The affidavit of an officer of the Transfer Agent or the Secretary or an
Assistant Secretary of Procept that such notice has been mailed shall, in the
absence of fraud, be prima facie evidence of the facts therein stated.  The
Transfer Agent may rely on the information in the certificate as true and
correct and has no duty nor obligation independently to verify the amounts or
calculations therein set forth.


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<PAGE>

       10.12  TREASURY STOCK.  Any Reset Issuance, Semi-Annual Issuance and
Dilution Issuance shall be made with duly authorized, fully-paid and 
non-assessable shares of Procept Common Stock, in accordance with the DGCL, and
shall be drawn from the treasury stock of Procept to the extent available.  

       10.13  MANDATORY TERMINATION OF SECTION 10 RIGHTS.  At any time on or
after the Reset Date, Procept may cause the Rights Holder's Section 10 Rights to
be terminated if the Market Price of the Procept Common Stock shall have
exceeded 300% of the then applicable Dilution Value as of the third business day
prior to the date of notice of termination.  No greater than 60 nor fewer than
20 days prior to the date of any such mandatory termination, notice by first
class mail, postage prepaid, shall be given to the Rights Holders, addressed to
such Rights Holders at their last addresses as they shall appear in the Transfer
Agent's record books.  Each such notice shall specify the date fixed for
termination.  Any notice which is mailed as herein provided shall be
conclusively presumed to have been duly given by Procept on the date deposited
in the mail, whether or not the Rights Holder receives such notice; and failure
properly to give such notice by mail, or any defect in such notice, to any
Rights Holders shall not affect the validity of the proceedings for the
termination of any other Rights Holders' Section 10 Rights.

       10.14  WAIVER OF SECTION 10 RIGHTS.  With the written consent of Procept
and the stockholders holding at least a majority of the issued and outstanding
Procept Common Stock subject to Section 10 Rights or subject to Article VI
Rights (as defined below), any provision of this Section 10 may be waived
(either generally or in a particular instance, either retroactively or
prospectively and either for a specified period of time or indefinitely) or
amended. Upon the effectuation of each such waiver or amendment, Procept shall
promptly give written notice thereof to the Rights Holders, if any, who have not
previously received notice thereof or consented thereto in writing.  "Article VI
Rights" are rights under a Subscription Agreement between a holder of Procept
Common Stock (or such holder's predecessor in interest) and Procept granting
rights referred to therein as "Article VI Rights", which rights are
substantially the same as the Section 10 Rights

       10.15  OPTIONAL EXCHANGE/RESET.

              10.15.1  Upon the receipt of requisite approvals, if any, from the
stockholders of Procept, the shares of Procept Common Stock acquired hereunder
may be exchanged (the "EXCHANGE RIGHT"), at the option of each Rights Holder,
upon the completion of a Qualified Offering (as defined below) into Qualified
Offering Securities (as defined below).  Upon exchange of their shares of
Procept Common Stock, up to the Issuance Base Amount, the exchanging Rights
Holders shall receive an amount of Qualified Offering Securities equal to the
quotient of (i) the Issuance Base Amount being exchanged multiplied by the
Dilution Value at the time of the Qualified Offering, divided by (ii) the
Qualified Offering Securities Price (as defined below) multiplied by .75 (the
"EXCHANGE PRICE"); provided, however, that in the event that the Exchange Price
divided by the Underlying Procept Common Stock Amount (as defined below) is less
than the greater of (a)  $2.50 and (b) 50% of the average closing bid price of
the Procept Common Stock for the twenty trading days immediately preceding the
date of such exchange (the "FLOOR PRICE"), then the Exchange Price shall equal
the Floor Price multiplied by the Underlying Procept Common Stock Amount.


                                     53

<PAGE>

       As used herein the following terms shall have the following meanings:

              (a)    "UNDERLYING PROCEPT COMMON STOCK AMOUNT" shall equal the
number of shares of Procept Common Stock and Procept Common Stock underlying
Convertible Securities included as part of each Qualified Offering Security but
shall not include Procept Common Stock underlying warrants or options to
purchase Procept Common Stock or to purchase a Convertible Security, whether or
not such warrant or option contains a right to exercise such warrant or option
by the delivery of shares deemed purchased thereunder, including, without
limitation, by a cashless exercise.

              (b)    "QUALIFIED OFFERING SECURITY" and "QUALIFIED OFFERING
SECURITIES" shall mean the security or securities (whether they are Procept
Common Stock, Convertible Securities, units of Procept Common Stock and/or
Convertible Securities (as defined below) and warrants or other similar rights)
issued or sold in the Qualified Offering (including any contractual rights
granted to investors in connection with the Qualified Offering).

              (c)    "QUALIFIED OFFERING" shall mean the sale or series of sales
of equity securities of Procept next occurring after the Effective Time of this
Offering, including, without limitation, Procept Common Stock, warrants, units
of Procept Common Stock and warrants, other securities exchangeable, convertible
or exercisable for Procept Common Stock, alone or in units, whether in a public
offering or private placement, raising gross proceeds in excess of $2,500,000;
excluding, however, at Procept's option, a firm commitment underwritten public
offering.

              (d)    "QUALIFIED OFFERING SECURITIES PRICE" shall mean the
selling price to investors for each Qualified Offering Security.

              (e)    "CONVERTIBLE SECURITY" and "CONVERTIBLE SECURITIES" shall
mean any security convertible into or exchangeable for a share or shares of
Procept Common Stock without the payment of any additional consideration in such
conversion or exchange other than the delivery of such security, but shall not
include a warrant or option to purchase Procept Common Stock or to purchase a
Convertible Security, whether or not such warrant or option contains a right to
exercise such warrant or option by the delivery of shares deemed purchased
thereunder, including, without limitation, by a cashless exercise.

              10.15.2  Upon and to the extent of any exchange into Qualified
Offering securities as set forth in Section 10.15.1 above, the Section 10 Rights
related to the exchanged Procept Common Stock shall terminate.

              10.15.3  Upon the receipt of requisite approvals, if any, from the
stockholders of Procept, holders who elect not to exchange their Procept Common
Stock upon a Qualified Offering for Qualified Offering Securities, shall have
the Dilution Value with respect to their Section 10 Rights adjusted (a
"QUALIFIED OFFERING ADJUSTMENT EVENT") to equal the Exchange Price and shall
receive an additional number of shares (the "QUALIFIED OFFERING ISSUANCE") of
Procept Common Stock equal to the difference between (i) the quotient of (a) the
Issuance Base Amount multiplied by the Dilution Value in effect prior to the
date of adjustment divided by (b) the (x) Exchange Price divided by (y) the
Underlying Procept Common Stock Amount, and (ii) 


                                 54

<PAGE>

the Issuance Base Amount prior to the date of adjustment; provided, however, 
that no adjustment shall be made if it would result in an increase in the 
Dilution Value.  Holders receiving Qualified Offering Issuance shall have 
Section 10 Rights with respect to such shares.

                              SECTION 11 - MISCELLANEOUS

       11.1   NOTICES.  Any notice or other communication required or permitted
hereunder shall be in writing and shall be deemed given when so delivered in
person, by overnight courier, by facsimile transmission (with receipt confirmed
by telephone or by automatic transmission report) or two business days after
being sent by registered or certified mail (postage prepaid, return receipt
requested), as follows:

       (i)    if to Procept, to:

              Procept, Inc.
              840 Memorial Drive
              Cambridge, MA  02139 
              Attention:  John Dee
              Tel:  (617) 491-1100
              Fax:  (617) 491-9019

       with a copy to:

              Palmer & Dodge LLP
              One Beacon Street
              Boston, Massachusetts  02108
              Attention:  Lynnette C. Fallon, Esq.
              Tel: (617) 573-0220
              Fax: (617) 227-4420

       (ii)   if to Pacific, to:

              Pacific Pharmaceuticals, Inc.
              6730 Mesa Ridge Road, Suite A
              San Diego, CA  92121
              Attention:  H. Laurence Shaw
              Tel:  (619) 550-3900
              Fax:  (619) 550-3929

       with a copy to:

              Patterson, Belknap, Webb & Tyler LLP
              1133 Avenue of the Americas
              New York, NY 10036-6710
              Attention:  Edward F. Cox, Esq.
              Tel: (212) 336-2000
              Fax: (212) 336-2222



                                   55

<PAGE>

Any party may by notice given in accordance with this Section 11.1 to the other
parties designate another address or person for receipt of notices hereunder.

       11.2   AMENDMENT.  Except as provided in Section 10.14, this Agreement
may not be amended except by an instrument signed by each party hereto.

       11.3   WAIVER.  At any time prior to the Effective Time, any party hereto
may, (a) extend the time for the performance of any of the obligations or other
acts of any other party hereto or (b) waive compliance with any of the
agreements of any other party or any conditions to its own obligations, in each
case only to the extent such obligations, agreements and conditions are intended
for its benefit; provided that any such extension or waiver shall be binding
upon a party only if such extension or waiver is set forth in a writing executed
by such party.  After the Effective Time, such extension or waiver may be made
in accordance with Section 10.

       11.4   ENTIRE AGREEMENT.  This Agreement contains the entire agreement
among the parties with respect to the Merger and related transactions, and
supersedes all prior agreements, written or oral, with respect thereto,
including but not limited to the Letter of Intent dated November 4, 1998.

       11.5   GOVERNING LAW.  This Agreement is governed by the laws of the
State of Delaware without regard to its conflict of law provisions.

       11.6   BINDING EFFECT; NO ASSIGNMENT.  This Agreement shall be binding
upon and inure to the benefit of the parties and their respective successors and
permitted assigns.  The Rights Holders are intended to be, and shall be, third
party beneficiaries of Section 10 hereof.  This Agreement is not assignable
without the prior written consent of the other parties hereto, provided that the
Section 10 Rights are assignable as set forth in Section 10.9.

       11.7   VARIATIONS IN PRONOUNS.  All pronouns and any variations thereof
refer to the masculine, feminine or neuter,  singular or plural, as the context
may require.

       11.8   COUNTERPARTS.  This Agreement may be executed in two or more
counterparts, each of which shall be deemed an original, and all of which
together shall constitute one and the same instrument.

       11.9   EXHIBITS AND DISCLOSURE SCHEDULES.  The Exhibits and Disclosure
Schedules are a part of this Agreement as if fully set forth herein.


                                  56

<PAGE>

       IN WITNESS WHEREOF, the parties have executed this Agreement under seal
as of the date first stated above.

                                   PROCEPT, INC.

                                   By   /s/ John F. Dee
                                   ----------------------------------------
                                   Name: John F. Dee
                                   Title:  President and CEO

                                   PACIFIC PHARMACEUTICALS, INC.


                                   By  /s/ H. Laurence Shaw
                                   ----------------------------------------
                                   Name: H. Laurence Shaw, M. D.
                                   Title: Chairman, President and CEO
              
              
                                   PROCEPT ACQUISITION CORP.


                                   By   /s/ John F. Dee
                                   ----------------------------------------
                                   Name: John F. Dee
                                   Title:  President and CEO


                              57

<PAGE>


                                  TABLE OF CONTENTS
                                     (CONTINUED)

<TABLE>
<CAPTION>
                                                                                 PAGE
<S>                                                                           <C>
SECTION 1 - THE MERGER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2

       1.1    The Merger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2

       1.2    Effective Time . . . . . . . . . . . . . . . . . . . . . . . . . . . .2

       1.3    Effects of the Merger. . . . . . . . . . . . . . . . . . . . . . . . .2

       1.4    Certificate of Incorporation and Bylaws. . . . . . . . . . . . . . . .3

       1.5    Directors and Officers . . . . . . . . . . . . . . . . . . . . . . . .3

       1.6    Conversion of Stock. . . . . . . . . . . . . . . . . . . . . . . . . .3

       1.7    Closing of Pacific Transfer Books. . . . . . . . . . . . . . . . . . .4

       1.8    Pacific Dissenting Shares. . . . . . . . . . . . . . . . . . . . . . .4

       1.9    Issuance of Procept Certificates . . . . . . . . . . . . . . . . . . .5

       1.10   No Fractional Shares . . . . . . . . . . . . . . . . . . . . . . . . .5

SECTION 2 -   REPRESENTATIONS AND WARRANTIES OF PAC. . . . . . . . . . . . . . . . .6

       2.1    Organization and Corporate Power . . . . . . . . . . . . . . . . . . .6

       2.2    Corporate Authorization. . . . . . . . . . . . . . . . . . . . . . . .6

       2.3    Non-Contravention. . . . . . . . . . . . . . . . . . . . . . . . . . .6

       2.4    No Business Activities.. . . . . . . . . . . . . . . . . . . . . . . .6

SECTION 3 -   REPRESENTATIONS AND WARRANTIES OF PACIFIC. . . . . . . . . . . . . . .6

       3.1    Organization and Qualification.. . . . . . . . . . . . . . . . . . . .6

       3.2    Capitalization.. . . . . . . . . . . . . . . . . . . . . . . . . . . .6

       3.3    Authority to Execute and Perform Agreements. . . . . . . . . . . . . .7

       3.4    Subsidiaries and Other Affiliates. . . . . . . . . . . . . . . . . . .7

       3.5    Charter and By-laws; Books and Records.. . . . . . . . . . . . . . . .7

       3.6    SEC Reports. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .8

       3.7    Financial Statements.. . . . . . . . . . . . . . . . . . . . . . . . .8

       3.8    Absence of Undisclosed Liabilities . . . . . . . . . . . . . . . . . .8

       3.9    No Material Adverse Change.. . . . . . . . . . . . . . . . . . . . . .8

       3.10   Tax Matters. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .9

       3.11   Compliance with Laws.. . . . . . . . . . . . . . . . . . . . . . . . 11

       3.12   Consents; No Breach. . . . . . . . . . . . . . . . . . . . . . . . . 12

       3.13   Actions and Proceedings. . . . . . . . . . . . . . . . . . . . . . . 12

</TABLE>

                                         -i-

<PAGE>

                                  TABLE OF CONTENTS
                                     (CONTINUED)

<TABLE>
<CAPTION>
                                                                                 PAGE
<S>                                                                           <C>
       3.14   Contracts and Other Agreements.. . . . . . . . . . . . . . . . . . . 13

       3.15   Real Property; Leases. . . . . . . . . . . . . . . . . . . . . . . . 14

       3.16   Tangible Property. . . . . . . . . . . . . . . . . . . . . . . . . . 15

       3.17   Intellectual Property. . . . . . . . . . . . . . . . . . . . . . . . 15

       3.18   Title to Assets; Liens.. . . . . . . . . . . . . . . . . . . . . . . 15

       3.19   Employee Benefit Plans.. . . . . . . . . . . . . . . . . . . . . . . 16

       3.20   Employee Relations . . . . . . . . . . . . . . . . . . . . . . . . . 17

       3.21   Relationships with Affiliates. . . . . . . . . . . . . . . . . . . . 17

       3.22   Insurance. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17

       3.23   Brokerage. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17

       3.24   Hazardous Materials. . . . . . . . . . . . . . . . . . . . . . . . . 18

       3.25   Full Disclosure. . . . . . . . . . . . . . . . . . . . . . . . . . . 18

SECTION 4 -   REPRESENTATIONS AND WARRANTIES OF PROCEPT. . . . . . . . . . . . . . 18

       4.1    Organization and Qualification.. . . . . . . . . . . . . . . . . . . 19

       4.2    Capitalization.. . . . . . . . . . . . . . . . . . . . . . . . . . . 19

       4.3    Authority to Execute and Perform Agreements. . . . . . . . . . . . . 19

       4.4    Subsidiaries and Other Affiliates. . . . . . . . . . . . . . . . . . 20

       4.5    Charter and By-laws; Books and Records.. . . . . . . . . . . . . . . 20

       4.6    SEC Reports. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20

       4.7    Financial Statements.. . . . . . . . . . . . . . . . . . . . . . . . 20

       4.8    Absence of Undisclosed Liabilities . . . . . . . . . . . . . . . . . 20

       4.9    No Material Adverse Change.. . . . . . . . . . . . . . . . . . . . . 21

       4.10   Tax Matters. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22

       4.11   Compliance with Laws.. . . . . . . . . . . . . . . . . . . . . . . . 23

       4.12   Consents; No Breach. . . . . . . . . . . . . . . . . . . . . . . . . 24

       4.13   Actions and Proceedings. . . . . . . . . . . . . . . . . . . . . . . 24

       4.14   Contracts and Other Agreements.. . . . . . . . . . . . . . . . . . . 25

       4.15   Real Property; Leases. . . . . . . . . . . . . . . . . . . . . . . . 26

       4.16   Tangible Property. . . . . . . . . . . . . . . . . . . . . . . . . . 27

       4.17   Intellectual Property. . . . . . . . . . . . . . . . . . . . . . . . 27

</TABLE>
                                       -ii-


<PAGE>

                                  TABLE OF CONTENTS
                                     (CONTINUED)

<TABLE>
<CAPTION>
                                                                                 PAGE
<S>                                                                          <C>
       4.18   Title to Assets; Liens.. . . . . . . . . . . . . . . . . . . . . . . 27

       4.19   Employee Benefit Plans.. . . . . . . . . . . . . . . . . . . . . . . 28

       4.20   Employee Relations . . . . . . . . . . . . . . . . . . . . . . . . . 29

       4.21   Relationships with Affiliates. . . . . . . . . . . . . . . . . . . . 29

       4.22   Insurance. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29

       4.23   Brokerage. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29

       4.24   Hazardous Materials. . . . . . . . . . . . . . . . . . . . . . . . . 30

       4.25   Full Disclosure. . . . . . . . . . . . . . . . . . . . . . . . . . . 30

SECTION 5 -   COVENANTS AND AGREEMENTS . . . . . . . . . . . . . . . . . . . . . . 30

       5.1    Conduct of Pacific Business. . . . . . . . . . . . . . . . . . . . . 30

       5.2    Conduct of Procept Business. . . . . . . . . . . . . . . . . . . . . 32

       5.3    Nasdaq Listing . . . . . . . . . . . . . . . . . . . . . . . . . . . 33

       5.4    Agreement not to Entertain other Offers. . . . . . . . . . . . . . . 33

       5.5    Corporate Examinations and Investigations. . . . . . . . . . . . . . 34

       5.6    Expenses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34

       5.7    Authorization from Others. . . . . . . . . . . . . . . . . . . . . . 34

       5.8    Consummation of Agreement. . . . . . . . . . . . . . . . . . . . . . 35

       5.9    Further Assurances . . . . . . . . . . . . . . . . . . . . . . . . . 35

       5.10   Securities Law Matters . . . . . . . . . . . . . . . . . . . . . . . 35

       5.11   Pacific Stockholder Meeting. . . . . . . . . . . . . . . . . . . . . 35

       5.12   Procept Stockholder Meeting. . . . . . . . . . . . . . . . . . . . . 36

       5.13   Public Announcements and Confidentiality . . . . . . . . . . . . . . 36

       5.14   Affiliate Letters. . . . . . . . . . . . . . . . . . . . . . . . . . 36

       5.15   Procept SEC Filings. . . . . . . . . . . . . . . . . . . . . . . . . 37

       5.16   Pacific SEC Filings. . . . . . . . . . . . . . . . . . . . . . . . . 37

       5.17   Fairness Opinions. . . . . . . . . . . . . . . . . . . . . . . . . . 37

       5.18   Stock Options and Warrants . . . . . . . . . . . . . . . . . . . . . 37

       5.19   Indemnification, Directors and Officer's Insurance . . . . . . . . . 39

SECTION 6 -   CONDITIONS PRECEDENT TO THE OBLIGATIONS OF EACH 
              PARTY TO CONSUMMATE THE MERGER . . . . . . . . . . . . . . . . . . . 39

</TABLE>

                                         -iii-

<PAGE>

                                  TABLE OF CONTENTS
                                     (CONTINUED)

<TABLE>
<CAPTION>
                                                                                 PAGE
<S>                                                                           <C>
       6.1    Approvals. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39

       6.2    Absence of Order.. . . . . . . . . . . . . . . . . . . . . . . . . . 40

       6.3    Nasdaq Stock Exchange Listing. . . . . . . . . . . . . . . . . . . . 40

       6.4    Effectiveness of Registration Statement. . . . . . . . . . . . . . . 40

       6.5    Procept Fairness Opinion . . . . . . . . . . . . . . . . . . . . . . 40

       6.6    Pacific Fairness Opinion . . . . . . . . . . . . . . . . . . . . . . 40

SECTION 7 -   CONDITIONS PRECEDENT TO THE OBLIGATION OF PROCEPT 
              TO CONSUMMATE THE MERGER . . . . . . . . . . . . . . . . . . . . . . 40

       7.1    Representations, Warranties and Covenants. . . . . . . . . . . . . . 40

       7.2    Certificate of Secretary of Pacific. . . . . . . . . . . . . . . . . 40

       7.3    Affiliate Letters. . . . . . . . . . . . . . . . . . . . . . . . . . 40

       7.4    Opinion of Counsel to Pacific. . . . . . . . . . . . . . . . . . . . 41

       7.5    Merger Certificate . . . . . . . . . . . . . . . . . . . . . . . . . 41

       7.6    BTI Merger Agreement . . . . . . . . . . . . . . . . . . . . . . . . 41

       7.7    Agreement with Lenders . . . . . . . . . . . . . . . . . . . . . . . 41

       7.8    Approvals. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41

       7.9    Dissenting Shares. . . . . . . . . . . . . . . . . . . . . . . . . . 41

       7.10   Bank Accounts. . . . . . . . . . . . . . . . . . . . . . . . . . . . 41

       7.11   Certificates . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41

SECTION 8 -   CONDITIONS PRECEDENT TO THE OBLIGATION OF PACIFIC 
              TO CONSUMMATE THE MERGER . . . . . . . . . . . . . . . . . . . . . . 41

       8.1    Representations, Warranties and Covenants. . . . . . . . . . . . . . 41

       8.2    Certificate of Secretary of Procept. . . . . . . . . . . . . . . . . 42

       8.3    Certificate of Secretary of PAC. . . . . . . . . . . . . . . . . . . 42

       8.4    Approvals. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42

       8.5    Opinion of Counsel to Procept. . . . . . . . . . . . . . . . . . . . 42

       8.6    Certificates . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42

SECTION 9 -   TERMINATION, AMENDMENT AND WAIVER. . . . . . . . . . . . . . . . . . 42

       9.1    Termination. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42

       9.2    Effect of Termination. . . . . . . . . . . . . . . . . . . . . . . . 43

SECTION 10 -  ADDITIONAL CONTRACTUAL RIGHTS. . . . . . . . . . . . . . . . . . . . 43

</TABLE>
                                           -iv-
<PAGE>

                                  TABLE OF CONTENTS
                                     (CONTINUED)

<TABLE>
<CAPTION>
                                                                                 PAGE
<S>                                                                           <C>
       10.1   Definitions. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43

       10.2   Reset. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46

       10.3   Reset Issuance . . . . . . . . . . . . . . . . . . . . . . . . . . . 46

       10.4   Semi-Annual Issuances. . . . . . . . . . . . . . . . . . . . . . . . 46

       10.5   Dilution Issuances . . . . . . . . . . . . . . . . . . . . . . . . . 46

       10.6   Anti-Dilution Adjustments. . . . . . . . . . . . . . . . . . . . . . 46

       10.7   Change of Shares Adjustments.. . . . . . . . . . . . . . . . . . . . 50

       10.8   Liquidation Put. . . . . . . . . . . . . . . . . . . . . . . . . . . 51

       10.9   Transfer of Rights Under This Section 10.. . . . . . . . . . . . . . 51

       10.11  Notices. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52

       10.12  Treasury Stock.. . . . . . . . . . . . . . . . . . . . . . . . . . . 53

       10.13  Mandatory Termination of Section 10 Rights.. . . . . . . . . . . . . 53

       10.14  Waiver of Section 10 Rights. . . . . . . . . . . . . . . . . . . . . 53

       10.15  Optional Exchange/Reset. . . . . . . . . . . . . . . . . . . . . . . 53

SECTION 11 -  MISCELLANEOUS. . . . . . . . . . . . . . . . . . . . . . . . . . . . 55

       11.1   Notices. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55

       11.2   Amendment. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56

       11.3   Waiver . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56

       11.4   Entire Agreement . . . . . . . . . . . . . . . . . . . . . . . . . . 56

       11.5   Governing Law. . . . . . . . . . . . . . . . . . . . . . . . . . . . 56

       11.6   Binding Effect; No Assignment. . . . . . . . . . . . . . . . . . . . 56

       11.7   Variations in Pronouns . . . . . . . . . . . . . . . . . . . . . . . 56

       11.8   Counterparts.. . . . . . . . . . . . . . . . . . . . . . . . . . . . 56

       11.9   Exhibits and Disclosure Schedules. . . . . . . . . . . . . . . . . . 56

</TABLE>

                                               -v-

<PAGE>

 DISCLOSURE SCHEDULES (Delivered concurrently; Not attached hereto)

     Pacific Disclosure Schedule
     Procept Disclosure Schedule




                                       -vi-

<PAGE>

                                                                  EXHIBIT 10.45
                                   Procept, Inc.
                             Procept Acquisition Corp.
                                 840 Memorial Drive
                                Cambridge, MA  02139


                                   February 8, 1999



Pacific Pharmaceuticals, Inc.
6730 Mesa Ridge Road, Suite A
San Diego, CA  92121

Re:  Amendment to Agreement and Plan of Merger
     -----------------------------------------

Dear Sirs or Madams:

          On December 10, 1998, Procept, Inc., a Delaware corporation
("Procept"), Pacific Pharmaceuticals, Inc., a Delaware corporation ("Pacific"),
and Procept Acquisition Corp., a Delaware corporation ("PAC"), entered into an
Agreement and Plan of Merger (the "Merger Agreement").  Capitalized terms used
herein but not otherwise defined shall have the meanings ascribed to them in the
Merger Agreement.  

          Pursuant to the merger contemplated by the Merger Agreement (the
"Merger"), each holder of Pacific's Series A Convertible Preferred Stock, $25.00
par value ("Pacific Preferred Stock"), shall receive shares of Procept Common
Stock (the "Merger Shares") and certain contractual rights set forth in Section
10 of the Merger Agreement (the "Section 10 Rights").  It is the parties
understanding that, under present circumstances, the issuance of Procept Common
Stock to the holders of Pacific Common Stock in the Merger will cause a Dilution
Event (the "Merger Dilution Event") under the anti-dilution rights contained in
Article VI of Subscription Agreements entered into by certain holders of Procept
Common Stock who purchased their shares in a 1998 private placement (the
"Article VI Rights Holders").

          The parties hereby confirm that it is their intent that the Merger
have the equivalent effect for the holders of Pacific Preferred Stock and the
Article VI Rights Holders.  Accordingly, notwithstanding anything to the
contrary set forth in the Merger Agreement, the parties hereby agree that the
holders of Pacific Preferred Stock shall receive such number of additional
shares of Procept Common Stock (the "Dilution Shares") as they would have
received due to the Merger Dilution Event had they been Article VI Rights
Holders immediately prior to the time of the Merger.  (Under present
circumstances, the parties understand and agree that 417,137 Dilution Shares
shall be issued to holders of Pacific Preferred Stock due to the Merger Dilution
Event).
                                     
<PAGE>


          If the foregoing is in accordance with your understanding of our
agreement, please sign and return to Procept a counterpart hereof, whereupon
this instrument, together with all counterparts, will become a binding agreement
in accordance with its terms.

                                   Very truly yours,

                                   PROCEPT, INC.


                                   By:   /s/ John F. Dee
                                     ------------------------------
                                        John F. Dee
                                        President and CEO


                                   PROCEPT ACQUISITION CORP.


                                   By:   /s/ John F. Dee
                                      -----------------------------
                                        John F. Dee
                                        President and CEO


Confirmed, accepted and agreed to
as of the date first above written

PACIFIC PHARMACEUTICALS, INC.


By:   /s/ Anil K. Singhal
     --------------------
     Anil K. Singhal
     Interim President and CEO



                                       2

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM PACIFIC
PHARMACEUTICALS, INC.  THIRD QUARTER FY 1999 CONSOLIDATED FINANCIAL STATEMENTS
AND IS QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL STATEMENTS.
</LEGEND>
       
<S>                             <C>
<PERIOD-TYPE>                   9-MOS
<FISCAL-YEAR-END>                          MAR-31-1999
<PERIOD-START>                             APR-01-1998
<PERIOD-END>                               DEC-31-1998
<CASH>                                       3,561,557
<SECURITIES>                                         0
<RECEIVABLES>                                   15,236
<ALLOWANCES>                                         0
<INVENTORY>                                          0
<CURRENT-ASSETS>                             3,640,054
<PP&E>                                               0
<DEPRECIATION>                                       0
<TOTAL-ASSETS>                               3,793,426
<CURRENT-LIABILITIES>                        1,135,516
<BONDS>                                         19,261
                                0
                                  5,570,161<F2>
<COMMON>                                       250,269
<OTHER-SE>                                 (3,181,881)
<TOTAL-LIABILITY-AND-EQUITY>                 3,793,426
<SALES>                                          6,136
<TOTAL-REVENUES>                               156,099
<CGS>                                           41,075
<TOTAL-COSTS>                                2,929,517
<OTHER-EXPENSES>                               131,585
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                                   0
<INCOME-PRETAX>                                      0
<INCOME-TAX>                                         0
<INCOME-CONTINUING>                        (2,786,995)
<DISCONTINUED>                                       0
<EXTRAORDINARY>                              3,294,381<F1>
<CHANGES>                                            0
<NET-INCOME>                               (6,081,376)
<EPS-PRIMARY>                                   (0.52)
<EPS-DILUTED>                                   (0.52)
<FN>
<F1>CONVERTIBLE PREFERRED STOCK DIVIDENDS
<F2>INCLUDES MINORITY INTEREST OF $4,665,323
</FN>
        

</TABLE>


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