GENZYME CORP
8-K, 2000-12-19
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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<PAGE>

                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D. C. 20549


                                    FORM 8-K
                 CURRENT REPORT PURSUANT TO SECTION 13 OR 15(D)
                     OF THE SECURITIES EXCHANGE ACT OF 1934


                DATE OF REPORT (DATE OF EARLIEST EVENT REPORTED):
                                DECEMBER 18, 2000


                               GENZYME CORPORATION
             (Exact name of registrant as specified in its charter)


           MASSACHUSETTS                 0-14680               06-1047163
 (State or other jurisdiction of    (Commission file         (IRS employer
  incorporation or organization)         number)         identification number)


               ONE KENDALL SQUARE, CAMBRIDGE, MASSACHUSETTS 02139
               (Address of Principal Executive Offices) (Zip Code)


               Registrant's telephone number, including area code:
                                 (617) 252-7500

<PAGE>

ITEM 5.  OTHER EVENTS.

PURPOSE OF THIS REPORT

         The purpose of this Current Report is to report upon

         -        the filing with the Secretary of Commonwealth of Massachusetts
                  by Genzyme Corporation ("Genzyme"), and the effectiveness of,
                  an amendment and restatement of Genzyme's corporate charter
                  (the "Amendment") solely to

                  (1)      cancel its Genzyme Surgical Products Division Common
                           Stock (the "Surgical Products Stock") and its Genzyme
                           Tissue Repair Common Stock (the "Tissue Repair
                           Stock") and create its Genzyme Biosurgery Division
                           Common Stock , $0.01 par value (the "Biosurgery
                           Stock"), and

                  (2)      cancel its Series B Junior Participating Preferred
                           Stock and Series D Junior Participating Preferred
                           Stock and create a new Series B Junior Participating
                           Preferred Stock;

         -        the adoption of a revised set of Management and Accounting
                  Policies Governing the Relationship of Genzyme Divisions
                  ("Divisional Policies") solely to reflect the elimination of
                  the Genzyme Surgical Products Division and the Genzyme Tissue
                  Repair Division and the creation of the Genzyme Biosurgery
                  Division; and

         -        the amendment of the Company's Amended and Restated Renewed
                  Rights Agreement (the "Amended Rights Agreement") between
                  Genzyme and American Stock Transfer & Trust Company, as Rights
                  Agent solely to reflect the cancellation of the purchase
                  rights associated with Surgical Products Stock and the Tissue
                  Repair Stock and the creation purchase rights associated with
                  the Biosurgery Stock.

The Amendment was filed with the Secretary of the Commonwealth of Massachusetts
on December 18, 2000, becoming automatically effective at 11:59 p.m. on such
date (the "Effective Time"). The Amended Rights Agreement is effective as of the
Effective Time.

Set forth below is a description of

         -        the terms of the Biosurgery Stock created by the Amendment,
         -        the Divisional Policies, and
         -        Amended Rights Agreement, including a description of the
                  purchase rights associated with the Biosurgery Stock and the
                  new Series B Junior Participating Preferred Stock.

5(a)     DESCRIPTION OF BIOSURGERY STOCK AND DIVISIONAL POLICIES


         For a description of the Biosurgery Stock and the Divisional Policies
see the description contained in Genzyme's Registration Statement on Form 8-A
(File No. 0-14680) registering such security as filed with the Securities and
Exchange Commission (the "Commission") on December 19, 2000, which description
is hereby incorporated herein by reference. That description of the Biosurgery
Stock and the Divisional Policies is qualified in its entirety by reference to
the more complete description of the terms of such security and policies as
contained in the Genzyme's Restated Articles of Organization and its Divisional
Policies, which are filed as Exhibits 1 and 3, respectively, to that
registration statement and is incorporated herein by reference.

<PAGE>

5(b)     DESCRIPTION OF THE AMENDED RIGHTS AGREEMENT

         For a description of the Amended Rights Agreement, see the description
contained in Genzyme's Registration Statement on Form 8-A (File No. 0-14680)
registering the purchase rights associated with Genzyme's common stock filed
with the Securities and Exchange Commission (the "Commission") on December 19,
2000, which description is hereby incorporated herein by reference. That
description of the Amended Rights Agreement is qualified in its entirety by
reference to the Amended Rights Agreement itself, which is filed as Exhibit 4 to
that registration statement and is incorporated herein by reference.

ITEM 7.  FINANCIAL STATEMENTS, PRO FORMA FINANCIAL INFORMATION AND EXHIBITS.

         (c)      EXHIBITS:
<TABLE>
<CAPTION>
Exhibit No.          Description
-----------          -----------
<S>                  <C>
1.                   Related Articles of Organization of Genzyme filed with the
                     Secretary of the Commonwealth of Massachusetts on December
                     18, 2000. Filed as Exhibit 1 to Genzyme's Registration
                     Statement on Form 8-A registering Genzyme Biosurgery
                     Division Common Stock, filed with the SEC on December 19,
                     2000.

2.                   Managing and Accounting Policies Governing the Relationship
                     of Genzyme Divisions. Filed as Exhibit 3 to Genzyme's
                     Registration Statement on Form 8-A registering Genzyme
                     Biosurgery Division Common Stock, filed with the SEC on
                     December 19, 2000.

3.                   Second Amended and Restated Renewed Rights Agreement dated
                     December 18, 2000 between Genzyme and American Stock
                     Transfer & Trust Company, as Rights Agent. Filed as Exhibit
                     4 to Genzyme's Registration Statement on Form 8-A
                     registering GBS Purchase Rights, filed with the SEC on
                     December 19, 2000.
</TABLE>

<PAGE>

                                    SIGNATURE


           Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.


                                      GENZYME CORPORATION


Dated:   December 18, 2000            By: /s/  Michael Wyzga
                                         ---------------------------------------
                                          Michael Wyzga, Senior Vice President
                                          and Chief Financial Officer

<PAGE>

                                  EXHIBIT INDEX

<TABLE>
<CAPTION>
Exhibit No.          Description
-----------          -----------
<S>                  <C>
1.                   Related Articles of Organization of Genzyme filed with the
                     Secretary of the Commonwealth of Massachusetts on December
                     18, 2000. Filed as Exhibit 1 to Genzyme's Registration
                     Statement on Form 8-A registering Genzyme Biosurgery
                     Division Common Stock, filed with the SEC on December 19,
                     2000.

2.                   Managing and Accounting Policies Governing the Relationship
                     of Genzyme Divisions. Filed as Exhibit 3 to Genzyme's
                     Registration Statement on Form 8-A registering Genzyme
                     Biosurgery Division Common Stock, filed with the SEC on
                     December 19, 2000.

3.                   Second Amended and Restated Renewed Rights Agreement dated
                     December 18, 2000 between Genzyme and American Stock
                     Transfer & Trust Company, as Rights Agent. Filed as Exhibit
                     4 to Genzyme's Registration Statement on Form 8-A
                     registering GBS Purchase Rights, filed with the SEC on
                     December 19, 2000.
</TABLE>



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