BIOPHARMACEUTICS INC
8-K, 1997-06-09
PHARMACEUTICAL PREPARATIONS
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                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                    FORM 8-K

                    Current Report Pursuant to Section 13 or
                  15(d) of the Securities Exchange Act of 1934


           Date of Report (date of earliest event reported): June 1997

                             BIOPHARMACEUTICS, INC.
             (Exact name of Registrant as specified in its Charter)

      DELAWARE                           1-9370                    13-3186327
     (State or other             (commission File Number)      (I.R.S Employer
     jurisdiction of                                            I.D. Number)
     incorporation)

     990 Station Road
     Bellport, New York                                         11713
     (Address of principal executive offices)                  (Zip Code)


       Registrant's telephone number, including area code: (516-286-5800)


                                       N/A
          (Former name or former  address,  if changed since last report.)



<PAGE>


ITEM 2.           ACQUISITION OR DISPOSITION OF ASSETS

     On April 30, 1997 the Company signed a Letter of Intent, Amended on June 2,
1997 to purchase 100% of the stock of privately owned Caribbean  Medical Testing
Center ("CMT") of San Juan, Puerto Rico for $7,500,000.  in the form of cash and
notes.  CMT is a  multi-phase  specialty  medical  testing  center and reference
laboratory  with a license to provide  services  throughout  Puerto Rico and the
U.S. Virgin Islands.
     The Company is presently  arranging  for  financing and expects to sign the
formal acquisition agreement by June 12, 1997.



                                  EXHIBIT INDEX

                           Current Report on Form 8-K

                                       of

                             Biopharmaceutics, Inc.

                          Date of Report: June 6, 1997


                  Exhibit:

                  28.17             Press Release  dated June 5, 1997

                  28.18             Letter of Intent dated April 30, 1997
                                    and Amendments



<PAGE>



                                   SIGNATURES

     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
Registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.

                                      BIOPHARMACEUTICS, INC.
                                           (Registrant)



                                   By:      /s/  Edward Fine
                                            Edward Fine
                                            President, Chief Executive Officer
                                                    (Signature)

Dated:  June 6, 1997





<PAGE>


EXHIBIT  28.17


 Press Release       For Immediate Release



For More Information, Call:

Stuart Fine  (516) 286-5800


                  Biopharmaceutics, Inc. Announces Acquisition

     BELLPORT,  N.Y.  (June  5,  1997)  -  Biopharmaceutics,  Inc.  (BOPH:OTCBB)
announced  today that it has entered  into a Letter of Intent to acquire 100% of
the stock of  privately-owned  Caribbean  Medical  Testing Center ("CMT") of San
Juan,  Puerto Rico for $7,500,000 in the form of cash and notes. The acquisition
is subject to the completion of Due Diligence and the  availability  of adequate
financing. The formal acquisition agreement is expected to be signed by June 12,
1997.
     CMT  is a  multi-phase  specialty  medical  testing  center  and  reference
laboratory  with a license to provide  services  throughout  Puerto Rico and the
U.S. Virgin Islands. For its first quarter ended March 31, 1997, CMT's unaudited
financial  statements  reflected  revenues  of $776,000  and  pre-tax  income of
$45,000.  On June 4, 1997, CMT entered into a contract to provide  reference lab
services to a major medical provider in conjunction with that medical provider's
contract  with the Puerto  Rico  Health  Insurance  Administration.  The medical
provider's  contract  with CMT  provides  for  payments to CMT of  approximately
$465,000 per month,  or $5,580,000  per year.  Taking the new contract  revenues
into  consideration  when combined with on-going  projected income and expenses,
CMT management  projects CMT will earn approximately  $3,000,000 per year. Based
upon the current number of shares  outstanding,  such earnings  would  represent
approximately $ .05 to $ .07 per share to Biopharmaceutics.  In addition, CMT is
currently negotiating for additional contracts which may be completed before the
final closing of the acquisition. 
     Edward Fine, President of Biopharmaceutics,stated,  "We are pleased to have
the opportunity to acquire CMT. Last year, when we acquired the Feminine Hygiene
product lines from London  International U.S.  Holdings,  Inc., we stated it was
our  objective  to  aggressively  pursue  other  potential   acquisitions  where
favorable  financial  terms are  available and the  acquisitions  fit our stated
objectives. In the case of CMT, both of those conditions are in existence."
     Biopharmaceutics,   Inc.  is  a  Company  that   specializes   in  contract
pharmaceutical  manufacturing  and  marketing  of  feminine  hygiene  and family
planning products with the brand names Vaginex(R),  Koromex(R),  Koroflex(R) and
Feminique(R).  It is also  involved in a joint  venture with ABS Group,  Inc. to
commercialize Mitolactol(R), a cancer drug that has Orphan Drug Status for brain
and cervical cancers.

<PAGE>


EXHIBIT 28.18


                                LETTER OF INTENT


     This Letter of Intent is entered into between  Biopharmaceutics,  Inc., 990
Station  Road.,  Bellport,  New York  11713  (BIO),  Caribbean  Medical  Testing
Center., San Juan, Puerto Rico (CMT), Rufino Vale and his wife ("the Vales").

     WHEREAS, BIO is interested in acquiring 100% of CMT's common stock, and

     WHEREAS,  Rufino Vale and his wife are  interested in selling 100% of CMT's
common stock, the parties agree as follows:

     A. Subject to the  successful  conclusion  of proper Due  Diligence,  on or
before  June 2, 1997,  BIO will  purchase  100% of CMT's  common  stock from the
Vales.  Such purchase is subject to Due Diligence by BIO and a final contract of
sale adequate to all parties being  concluded.  If in BIO's sole discretion such
Due Diligence  does not result in an  evaluation to conclude the purchase,  then
neither party will have any further obligation to the other.

     B. BIO will pay $7,500,000 for 100% of CMT's common stock as follows:

     1. $100,000 by May 12, 1997. Such $100,000 will be paid to an escrow agent,
either BIO's attorney or CMT's attorney, and will be subject to return to BIO if
BIO decides not to proceed with the  transaction and notifies,  in writing,  CMT
and the Vales by June 2, 1997.  Should BIO fail to notify CMT and the Vales that
it is not proceeding with the purchase,  then the escrow agent shall, after June
2,  1997,  release  the funds to the Vales  and the Vales  will have no  further
obligation to BIO.

     2. BIO will pay $1  million  by June 16,  1997 to the Vales in  immediately
available  funds.  If such  payment  is not made,  then the  Vales  will have no
further  obligation to BIO and BIO will have no further  obligation to the Vales
and the Vales shall keep the $100,000 deposit.

     3. BIO will pay the balance of $6,400,000  on July 11, 1997, or sooner,  as
follows:
     a.  $1,500,000  in a note due July 11,  1999,  bearing  interest  at 6% per
annum, interest payable quarterly. Such note will be issued and payable by CMT.

     b. $4,900,000 in good and immediately available funds.

     C. BIO will enter into an  employment  agreement  with Angel Vale along the
terms spelled out in BIO's March 16th letter,  and in a form  satisfactory  with
terms satisfactory to both BIO and Angel.

     D. BIO will proceed to perform its Due Diligence  investigation  as quickly
as possible and shall advise CMT if the Due Diligence investigation results in a
non-purchase  decision  as quickly as  possible  after  such  decision  has been
reached.

     E.  Rufino  Vale  will   provide   BIO  with  the  usual   warranties   and
representations necessary to conclude a final purchase contract.

     F. It is understood by Rufino Vale that BIO will expend  substantial  funds
and invest  substantial  time in evaluating CMT's business and,  therefore,  the
only adequate  compensation  for a failure on the Vales' part not to conclude an
agreement with Bio, is specific performance.


Agreed to this 30th day of April 1997:


Biopharmaceutics, Inc.                           Rufino Vale, Individually
by:\s\ Edward Fine                               \s\Rufino Vale
      Edward Fine,
      President


                                             Caribbean Medical Testing Center

                                             by: \s\ Rufine Vale
                                             Rufino Vale, President

                                             Rufino Vale, for the Vales
                                             by: \s\ Rufino Vale



<PAGE>


                       FIRST AMENDMENT TO LETTER OF INTENT


     This first  amendment to the Letter of Intent is entered on this date among
Biopharmaceutics,  Inc.,  a  Delaware  corporation  ("BIO");  Caribbean  Medical
Testing Center,  Inc., a Puerto Rico corporation  ("CMT"), and by Rufino Vale on
his own behalf and on behalf of his wife,  Mirna Vazquez  Garcia  (collectively,
the "Vales").

                                  -WITNESSETH-

     Whereas,  BIO,  CMT and the Vales  executed and are parties to that certain
Letter of Intent dated April 30, 1997 (the "LOI");

     Whereas,  the LOI  relates to BIO's  acquisition  from the Vales of 100% of
CMT's common stock;

     Whereas,  the parties  wish to amend the LOI to reflect  the  modifications
contained herein;

     Wherefore,  for valuable and good consideration the sufficiency of which is
hereby acknowledged, the parties hereby agree as follows:

     1. The parties wish to amend the first  sentence of Section A of the LOI so
that it now reads as follows:

     A. Subject to the  successful  conclusion  of proper Due  Diligence,  on or
before  June 9, 1997,  BIO will  purchase  100% of CMT's  common  stock from the
Vales.

     The rest of Section A remains as stated in the LOI.

     2. The parties  wish to amend the second and third  sentences of Section B,
part 1 of the LOI so that it now reads as follows:


     "Such  $100,000  will be paid to the  Escrow  Agent and will be  subject to
return to BIO if BIO elects not to proceed with the transaction and notifies, in
writing CMT and the Vales by June 9, 1997. Should BIO fail to notify CMT and the
Vales that it is not proceeding with the purchase,  then the Escrow Agent shall,
after  June 9, 1997,  release  the funds to the Vales and the Vales will have no
further obligation to BIO."

     3. The parties  wish to amend  Section B, part 12 of the LOI so that it now
reads in its entirety as follows:

     "B.2.  BIO will pay $1 million by June 23, 1997 to the Vales in immediately
available  funds.  If such  payment  is not made,  then the  Vales  will have no
further  obligation to BIO and BIO will have no further  obligation to the Vales
and the Vales shall keep the $100,000 deposit".


     4. The parties  wish to amend  Section B., part 3 of the LOI so that it now
reads in its entirely as follows:

     "B.3.  BIO will pay the balance of  $6,400,000 on July 18, 1997, or sooner,
as follows:

     a)  $1,500,000 in a note due July 18, 1999,  bearing  interest at 10.5% per
annum, interest payable quarterly. Such note will be issued and payable by CMT.

     b) $4,900,000 in good and immediately available funds".

     5. The Vales and CMT acknowledge receipt of the $100,000 deposit on May 20,
1997  which  is to be held as  stated  in the  LOI  and in that  certain  Escrow
Agreement  dated as of May 12, 1997  between  the parties  hereto and the Escrow
Agent.

     6. Except as  otherwise  amended  hereby,  all of the rest of the terms and
conditions of the LOI shall remain in full force and effect.

         Agreed to this 20th day of May, 1997.

BIOPHARMACEUTICS, INC.                      CARIBBEAN MEDICAL TESTING
CENTER, INC.

 By:/s/  Edward Fine                  By:/s/  Rufino Vale
         Edward Fine                          Rufine N. Vale   
         President                            President         

                                      By:/s/  Mirna Vazquez Garcia
                                              Mirna Vazquez Garcia
                                              by: Rufino Vale    

 



<PAGE>


                    SECOND AMENDMENT TO THE LETTER OF INTENT

     The second  amendment to the Letter of Intent is entered on this date, June
2, 1997, among Biopharmaceutics, Inc., a Delaware corporation ("BIO"); Caribbean
Medical Testing Center,  Inc., a Puerto Rico  corporation  ("CMT") and by Rufino
Vale  on his  own  behalf  and on  behalf  of his  wife,  Myrna  Vazquez  Garcia
(collectively, the "Vales").

                                  -WITNESSETH-
     Whereas,  BIO,  CMT and the Vales  executed and are parties to that certain
Letter of Intent dated April 30, 1997 (the "LOI");  Whereas, the LOI was amended
on May 20, 1997 (the "First  Amendment");  Whereas,  the parties wish to further
amend  the  LOI  as  indicated   herein;   Wherefore,   for  valuable  and  good
consideration,  the  sufficiency  of which is hereby  acknowledged,  the parties
hereby agree as follows:

     1. The parties  wish to amend the second and third  sentences of Section B,
part 1 of the LOI,  and, as  indicated  in the First of Amendment so that it now
reads as follows:

     "Such  $100,000  will be paid to the  Escrow  Agent and will be  subject to
return to BIO if BIO elects not to proceed with the transaction and notifies, in
writing  CMT and the  Vales by June 12,  1997 on or before  5:00 PM Puerto  Rico
time. Should BIO fail to notify CMT and the Vales that it is not proceeding with
the purchase, then the Escrow Agent shall, after June 12, 1997 release the funds
to the Vales and the Vales will have no further obligation to BIO" .

     2. Except as otherwise  indicated  herein,  the LOI and the First amendment
remain in full force and effect.


     3. By the execution  hereof by BIO, CMT and the Vales, the Escrow Agreement
made as of May 12, 1997 among BIO, CMT, the Vales and the Escrow Agent is hereby
amended to reflect  that the  Deposit  shall be  released to either the Vales or
BIO, as the case may be, after June 12, 1997.



         Agreed to this 2nd day of June, 1997.
         BIOPHARMACEUTICS, INC.                      THE VALES

         By:/s/  Edward Fine                  By:/s/  Myrna Vazquez Garcia
         Edward Fine                                  Myrna Vazques Garcia
         President                                     by Rufino Vale

                                              By:/s/  Rufino Vale
                                                      Rufino Vale


CARIBBEAN MEDICAL TESTING CENTER, INC.


By:/s/  Rufino N. Vale
         Rufino N. Vale


Escrow Agent
Nevares, Sanchez-Alvarez & Gonzalez Nieto


By:/s/  Francisco Gonzalez Nieto
         Francisco Gonzalez Nieto




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