CAPITAL CONSULTANTS LLC
SC 13D, 1999-10-13
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                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                  SCHEDULE 13D

                   Under the Securities Exchange Act of 1934


                           A-FEM MEDICAL CORPORATION
          (fka Athena Medical Corp. -- name change effective 11/12/97)
          ------------------------------------------------------------
                                (Name of Issuer)

                     Common Stock, par value $.01 per share
                     --------------------------------------
                         (Title of Class of Securities)

                                   00105V105
                                   ---------
                                 (CUSIP Number)


                           Carmen M. Calzacorta, Esq.
                          Schwabe, Williamson & Wyatt
                     1211 SW Fifth Avenue, Suites 1600-1800
                          Portland, Oregon 97204-3795
                                  503-222-9981
               -------------------------------------------------
                 (Name, Address and Telephone Number of Person
               Authorized to Receive Notices and Communications)

                               September 22, 1999
            -------------------------------------------------------
            (Date of Event which Requires Filing of this Statement)

If the filing person has previously filed a statement on Schedule 13G to report
the acquisition that is the subject of this Schedule 13D, and is filing this
schedule because of ss.ss.240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the
following box.  [X]

NOTE: Schedules filed in paper format shall include a signed original and five
copies of the schedule, including all exhibits.  See ss.240.13d-7 for other
parties to whom copies are to be sent.

* The remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).


Potential persons who are to respond to the collection of information  contained
in this form are not  required to respond  unless the form  displays a currently
valid OMB control number.

                                       1
<PAGE>

CUSIP No. 00105V105
- -------------------
1.       Names of Reporting Persons.
         I.R.S. Identification Nos. of above persons (entities only)

         Capital Consultants LLC  (formerly Capital Consultants, Inc.)
         EIN 93-1269691

2.       Check the Appropriate Box if a Member of a Group (See Instructions)

                  (a)

                  (b)

3.       SEC Use Only

4.       Source of Funds (See Instructions)  OO; WC

5.       Check if Disclosure of Legal Proceedings Is Required Pursuant to Items
         2(d) or 2(e)

6.       Citizenship or Place of Organization    Oregon



Number of                  7.       Sole Voting Power                 56,991
Shares Beneficially
Owned by                   8.       Shared Voting Power            6,703,914
Each Reporting
Person With                9.       Sole Dispositive Power            56,991

                           10.      Shared Dispositive Power       6,703,914

11.      Aggregate Amount Beneficially Owned by Each Reporting Person  6,760,905

12.      Check if the Aggregate Amount in Row (11) Excludes Certain Shares
         (See Instructions)

13.      Percent of Class Represented by Amount in Row (11)    41.4%

14.               Type of Reporting Person (See  Instructions)  IA; OO - limited
                  liability company

                                       2
<PAGE>

CUSIP No. 00105V105
- -------------------

1.       Names of Reporting Persons.
         I.R.S. Identification Nos. of above persons (entities only)

         Jeffrey L. Grayson

2.       Check the Appropriate Box if a Member of a Group (See Instructions)

                  (a)

                  (b)

3.       SEC Use Only

4.       Source of Funds (See Instructions)  OO

5.       Check if Disclosure of Legal Proceedings Is Required Pursuant to Items
         2(d) or 2(e)

6.       Citizenship or Place of Organization    USA



Number of                  7.       Sole Voting Power                0
Shares Beneficially
Owned by                   8.       Shared Voting Power            6,760,905
Each Reporting
Person With                9.       Sole Dispositive Power         0

                           10.      Shared Dispositive Power       6,760,905

11.      Aggregate Amount Beneficially Owned by Each Reporting Person  6,760,905

12.      Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See
         Instructions)

13.      Percent of Class Represented by Amount in Row (11)    41.4%

14.      Type of Reporting Person (See Instructions)
                  IN

                                       3

<PAGE>


Item 1. Security and Issuer

a)   Name and Address of Principal Executive Offices of Issuer:

     A-FEM Medical Corporation ("Issuer")
     10180 SW Nimbus Avenue, Suite J5
     Portland, Oregon 97223

b)   Title and Class of Equity  Securities:  Common  Stock,  par value  $.01 per
     share ("Common Stock")

Item 2. Identity and Background

a)   -c), f)

Reporting Persons
- -----------------

This statement is filed by Capital  Consultants LLC, an Oregon limited liability
company (formerly,  Capital Consultants,  Inc., an Oregon corporation)  ("CCL"),
and  Jeffrey  L.  Grayson,  a  U.S.  citizen  ("Reporting  Persons").  CCL  is a
registered investment adviser engaged in providing investment advisory services.
Jeffrey L.  Grayson is the  Chairman  and Chief  Executive  Officer of CCL.  The
principal  business and office address of each of the Reporting  Persons is 2300
SW First Avenue, Suite 200, Portland, Oregon 97201.

Officers/Managers of CCL
- ------------------------

Barclay L. Grayson, a U.S. citizen, is the President of CCL.  Blake J. Grayson,
a U.S. citizen, is the Portfolio Manager of CCL. The principal business and
office address of Barclay L. Grayson and Blake J. Grayson is 2300 SW First
Avenue, Suite 200, Portland, Oregon 97201.

d) During the last five years none of the  Reporting  Persons or any  officer or
manager of CCL has been convicted in any criminal proceeding.

e) During the last five years none of the  Reporting  Persons or any  officer or
manager  of CCL  has  been  party  to any  civil  proceeding  of a  judicial  or
administrative  body of competent  jurisdiction as a result of which such person
would have been subject to any judgment,  decree or final order enjoining future
violations of or prohibiting or mandating activities subject to Federal or State
securities laws or finding any violation with respect to such laws.

The  filing of this  statement  on  Schedule  13D shall not be  construed  as an
admission that any Reporting Person or any officer of manager of CCL is, for the
purposes of Section 13(d) or 13(g) of the  Securities  Exchange Act of 1934, the
beneficial owner of any securities covered by this statement.

Item 3. Source and Amount of Funds or Other Consideration

In  August  1998,  CCL and the  Issuer  entered  into a Plan and  Agreement  for
Recapitalization  in which (i) 4,316,405  shares of Common Stock held by CCL for
its own account and on behalf of its  advisory  clients were  converted  into an
equal number of shares of Series A Convertible Preferred Stock ("Series A"), and
(ii) warrants to purchase  50,000 shares of Common Stock held by CCL for its own
account and on behalf of its advisory  clients were  converted  into warrants to
purchase an equal number of shares of Series A. Since August 1998,  CCL has used
its own funds and advisory client funds to purchase, for its

                                       4
<PAGE>

own account and on behalf of its advisory clients, additional shares of Series A
and warrants to purchase Series A in a series of separate  transactions with the
Issuer.  A list of the  clients  on whose  behalf  CCL  holds  the  Series A and
warrants to purchase Series A is attached as Appendix A.

Item 4. Purpose of the Transaction

The  transactions  described  above were  negotiated  with the Issuer.  Based on
continuing  evaluation  of the  Issuer's  business  and  prospects,  alternative
investment  opportunities,  economic and market conditions and all other factors
deemed relevant, CCL may continue to purchase, for its own account and on behalf
of its advisory clients,  additional shares of Series A and warrants to purchase
Series A, or some or all of the Issuer's Series A and warrants to purchas Series
A may be converted to Common Stock and sold. In addition,  CCL may purchase, for
its own account and on behalf of its advisory clients, shares of Common Stock in
the open market or in privately negotiated transactions.  Except as disclosed in
this Schedule  13D, the  Reporting  Persons have not made any proposals and have
not entered into any agreements which would be related to or would result in any
of the matters described in Items 4(a) through (j) of Schedule 13D; however,  as
part of their ongoing review of investment  alternatives,  the Reporting Persons
may consider  such  matters in the future and subject to  applicable  laws,  may
formulate a plan with respect to such matters  subject to  applicable  law, and,
from  time to time,  may  hold  discussions  with or make  formal  proposals  to
management or the Board of Directors of the Issuer,  other  stockholders  of the
Issuer or other third parties regarding such matters.

Item 5.  Interests in Securities of the Issuer

         (a) The  Reporting  Persons are deemed to be the  beneficial  owners of
6,710,905 shares of Series A and warrants to purchase 50,000 shares of Series A.
The  warrants  are  immediately  exercisable  into  Series A and the Series A is
immediately  convertible into an Common Stock on a one-to-one basis.  Therefore,
the Reporting  Persons are deemed to beneficially own 6,760,905 shares of Common
Stock which equals 41.4% of the outstanding Common Stock of the Issuer.

         (b) CCL has sole voting and  dispositive  power with  respect to 56,991
shares of Common Stock and is deemed to have shared voting and dispositive power
with respect to 6,703,914  shares of Common Stock.  Jeffrey L. Grayson is deemed
to have shared voting and dispositive  power with respect to 6,760,905 shares of
Common Stock.

         (c) On September 22, 1999, CCL purchased from the Issuer,  on behalf of
an advisory  client,  260,400 shares of Series A and warrants to purchase 52,080
shares of Series A, for a purchase  price of $499,968.  On August 19, 1999,  CCL
purchased from the Issuer,  on behalf of an advisory  client,  104,170 shares of
Series A and  warrants  to  purchase  20,834  shares of Series A, for a purchase
price of $200,006.40.

         (d) Each  advisory  client  listed on Appendix A is entitled to receive
dividends  from and the  proceeds  from the sale of the Series A and warrants to
purchase Series A held on their behalf.  The Oregon  Laborers-Employers  Pension
Trust is entitled to receive  dividends  from and the proceeds  from the sale of
more than 5% of the  outstanding  shares of Common Stock  (assuming all warrants
were exercised and all shares of Series A were converted to Common Stock).

         (e) Not applicable.

Item 6. Contracts, Arrangements, Understandings or Relationships with Respect to
Securities of the Issuer

The securities  held on behalf of the advisory  clients listed on Appendix A are
held on a  discretionary  basis by CCL and CCL is authorized to vote and dispose
of the securities.

A Preferred  Stock and Warrant  Purchase  Agreement is filed as Exhibit B hereto
and a Stock  Purchase  Warrant is filed as Exhibit C hereto.  All  purchases  of
Series A and warrants to purchase Series A made since August 1998 have been made
pursuant to Preferred Stock and Warrant  Purchase  Agreements and Stock Purchase
Warrants in substantially similar form to Exhibit B and Exhibit C, respectively.

The Amended  and  Restated  Registration  Rights  Agreement,  filed as Exhibit D
hereto,  provides  CCL  and  certain  of its  transferees,  subject  to  various
restrictions,   demand  and  piggyback   registration  rights  relating  to  the
underlying Common Stock of the Issuer received upon conversion of the Series A.

Item 7. Material to Be Filed as Exhibits

         Exhibit A: Joint Filing Agreement dated October 12, 1999 between CCL
                    and Jeffrey L. Grayson.

         Exhibit B: Preferred Stock and Warrant Purchase Agreement dated
                    September 22, 1999.

         Exhibit C: Stock Purchase Warrant dated September 22, 1999.

         Exhibit D: Amended and Restated  Registration  Rights  Agreement  dated
                    September 22, 1999 between CCL and the Issuer.



<PAGE>



                                   Signature

         After reasonable  inquiry and to the best of my knowledge and belief, I
certify that the information  set forth in this statement is true,  complete and
correct.

                                        Capital Consultants LLC

/s/ Jeffrey L. Grayson                  By: /s/ Jeffrey L. Grayson
- ----------------------------                ------------------------------
Jeffrey L. Grayson                          Jeffrey L. Grayson, Chairman & CEO


         Attention: Intentional misstatements or omissions of fact
         constitute Federal criminal violations (See 18 U.S.C. 1001).


                                       7

<PAGE>


                                   Appendix A

OPEIU Local #11
Oregon Laborers-Employers Pension Trust Fund
Susan Grayson
Betty Norrie
Virginia Mudd Revocable Trust
Guard Publishing Company
Richard & Carol Tinney
Robert E Maloney
CCI 401(k) Profit Sharing Plan
Idaho Laborers Pension Trust
Francis Kendrick
Diana C K Untermeyer
Margaret Kendrick Trust
Carl Shrader
Carl Shrader Money Purchase Plan & Trust
Donald & Maxine Barnard
James Pritchett
John Chaney
James & Patricia Murphy
Jerry Baker
Gary Gutterman, MD, PC Profit Sharing Plan
Gary & Sheila Gutterman
Patrick Files
Dean Kirkland
Joseph & Nancy Gabriel
Bay Point Properties
James & Nancy Case
The Erickson Group LTD
Blake & Erika Grayson
LLC Barclay Grayson Family LLC
Capital Consultants LLC

                                       8

<PAGE>



                                    Exhibit A

                             JOINT FILING AGREEMENT

         In accordance  with Rule 13d-1(k) under the Securities  Exchange Act of
1934, as amended,  each of the persons named below agrees to the joint filing of
a Statement on Schedule 13D (including  amendments  thereto) with respect to the
common stock of A-Fem Medical  Corporation,  a Nevada  corporation,  and further
agrees  that this  Joint  Filing  Agreement  be  included  as an exhibit to such
filings  provided that, as  contemplated by Section  13d-1(k)(l)(ii),  no person
shall  be  responsible  for the  completeness  or  accuracy  of the  information
concerning the other persons making the filing,  unless such person knows or has
reason to  believe  that such  information  is  inaccurate.  This  Joint  Filing
Agreement may be executed in any number of  counterparts,  all of which together
shall constitute one and the same instrument.

DATED:    October 12, 1999.

                                       Capital Consultants LLC

/s/ Jeffrey L. Grayson                 By: /s/ Jeffrey L. Grayson
- --------------------------             ------------------------------------
Jeffrey L. Grayson                     Jeffrey L. Grayson, Chairman and CEO


                                       1

<PAGE>


                                    Exhibit B
                            A-FEM MEDICAL CORPORATION

                           PREFERRED STOCK AND WARRANT
                               PURCHASE AGREEMENT


         Certain   investors   (each  an  "Investor"   and   collectively,   the
"Investors") acting through their agent,  Capital Consultants LLC ("CCL"),  have
agreed to  purchase  an  aggregate  of  260,400  shares of Series A  Convertible
Preferred  Stock  (the  "Shares"),  $.01 par value per share,  of A-Fem  Medical
Corporation,  a Nevada  corporation  (the  "Company"),  and warrants to purchase
52,080 shares of such Series A Convertible  Preferred Stock in the form attached
as Exhibit A (the  "Warrants")  in  consideration  of the  payment of the sum of
$499,968 (the "Consideration").  The Shares and Warrants are sometimes hereafter
referred  to  collectively  as the  "Securities."  Delivery  and payment for the
Securities shall occur as set forth in paragraph I.

         I.       Closing

         Closing of the transaction  will occur when this Agreement is executed.
At closing,  the Company will cause certificates for the Shares and the Warrants
to be  delivered  to CCL as  agent  for the  Investors  against  payment  of the
Consideration.

         II.      Investor Representations

         CCL, individually and, to CCL's reasonable belief, on behalf of each of
the Investors,  represents, warrants, acknowledges and agrees that the following
are true as of the date first below written:

         2.1 The Securities are not being registered under the Securities Act of
1933, as amended (the "Act"),  and applicable  state securities laws in reliance
upon exemptions from  registration and cannot be sold,  transferred or otherwise
disposed of by the Investor unless they are  subsequently  registered  under the
Act and applicable state securities laws or an exemption from such  registration
is available at the time of the desired sale. Therefore,  the Investor must bear
the economic risk of an investment in such Securities for an indefinite  period.
The Investor's right to require  registration  under federal or state securities
laws of such  Securities  is set  forth  in the  Registration  Rights  Agreement
attached hereto as Exhibit B. The Investor will under no  circumstances  attempt
to assign or otherwise  transfer all or any portion of such Securities except in
accordance with federal and state securities laws;

         2.2 No state or federal agency or instrumentality  has made any finding
or  determination  as to the  fairness  of the  terms  of  the  offering  or the
investment in the

                                       1


<PAGE>

Securities,  nor has any state or  federal  agency or  instrumentality  made any
recommendation with respect to any purchase or investment in the Securities;

         2.3 The Company has not paid and will not pay any commission or similar
remuneration  directly  or  indirectly  to any  person  in  connection  with the
acquisition of the Securities by the Investor,  and no dealer,  salesman, or any
other person  (other than  officers of the Company) has been  authorized to give
any information or to make any  representations in connection with the offer and
sale of the  Securities,  and if  given  or  made,  such  other  information  or
representation  must not have been relied upon as having been  authorized by the
Company;

         2.4 The  Company  will  rely  materially  upon  the   representations,
warranties,  covenants,  and agreements of the Investor set forth herein for the
purpose of offering and selling the Securities to the Investor;

         2.5 The Investor is acquiring such Securities solely for investment for
its own account and has no agreement, understanding or arrangement to subdivide,
sell,  assign,  transfer  or  otherwise  dispose  of  all or any  part  of  such
Securities to any other persons;

         2.6 The Investor and CCL have such substantial knowledge and experience
in financial  and business  matters in general,  and in similar  investments  in
particular, that they are capable of reading and understanding information about
the Company and  evaluating the merits and risks of an investment in the Company
and the merits and risks of the acquisition of the Securities;

         2.7 The  Investor  is  familiar  with the nature of and risk  attending
investments having the special  characteristics of common stock interests in the
Company and has determined on the basis of its own  familiarity and knowledge of
such  investments  that the purchase of the  Securities is  consistent  with its
investment  objectives  and income  prospects  and is making such an  investment
based on its own independent investigation;

         2.8 Investment in the  Securities  involves a degree of risk of loss by
the  Investor  of the  entire  investment  and  there is no  assurance,  and the
Investor has received no  assurance,  of any income from the  investment  in the
Securities;

         2.9 The Investor is aware that the  Securities  being  offered have not
been approved or disapproved by the SEC or any state securities  agency, nor has
any such regulatory body reviewed any information  with respect to the offer and
sale of such Securities;

                                       2

<PAGE>

         2.10 CCL  and  the  Investor  understand  that  no  private  placement
memorandum  has been  prepared  for this  investment  offering,  but CCL and the
Investor have received and read  information  with regard to this investment and
the Company, as required by applicable  securities laws and as required to allow
CCL and the  Investor to  adequately  evaluate  the  investment  and its related
merits and risks.  CCL and the Investor have the  capability  to determine  what
documents and  information  are necessary for CCL and the Investor to adequately
evaluate the Company and this investment, and CCL and the Investor also have the
capability to request, review and evaluate the necessary information;

         2.11 CCL and the Investor have had the  opportunity  to (i) examine and
have  examined  sources  of  information  that they  have  deemed  necessary  or
appropriate to reach an informed  investment decision concerning the purchase of
the  Securities,   including,   without  limitation,  the  physical  facilities,
financial  statements,  books,  records and files of the  Company,  and (ii) had
reasonable   opportunity  to  meet  with  representatives  of  the  Company  and
questioned the directors, shareholders and officers of the Company to the extent
that they have deemed  necessary or appropriate so as to receive  answers and to
verify the accuracy of the information  obtained in the above  examination.  CCL
and the Investor  acknowledge receipt of: a registration  statement on Form S-2,
filed with the SEC on June 28, 1999 relating to common stock of the Company; the
Company's annual report to the Securities and Exchange Commission (the "SEC") on
Form  10-KSB for the year ended  December  31,  1998;  the  Company's  quarterly
reports on Form 10-QSB for the quarters  ended March 31, 1999 and June 30, 1999;
the proxy statement relating to the Company's 1997 Annual Meeting; and the proxy
statement  relating to a Special Meeting of the Company's  shareholders  held on
December 12, 1997. CCL and the Investor  acknowledge that the Company  continues
to lose money, that it will require  additional  financing in both the short and
long term if it is to stay in business and that the failure to obtain additional
financing would likely result in the cessation of business;

         2.12 The Investor is an "accredited  investor" as defined in Securities
and Exchange Commission Rule 501(a) of Regulation D (17 CFR 230.501(a)) and is a
resident of one of the jurisdictions identified on Schedule 1;

         2.13 The financial  condition of the Investor is such that the Investor
is under no present need to dispose of any portion of the  Securities to satisfy
any existing or contemplated indebtedness;

         2.14 Each  certificate  representing  the Securities  shall be endorsed
with the following legend together with any other legends required by law:

                                       3

<PAGE>


         "The securities  evidenced by this Certificate have not been registered
under the  Securities  Act of 1933,  as amended (the "Act"),  or any  applicable
state law, and no interest therein may be sold, distributed,  assigned, offered,
pledged or otherwise  transferred unless (a) there is an effective  registration
statement under such Act and applicable  state securities laws covering any such
transaction  involving  said  securities  or (b) this  corporation  receives  an
opinion of legal  counsel for the holder of these  securities  (concurred  in by
legal counsel for this corporation) stating that such transaction is exempt from
registration  or  this   corporation   otherwise   satisfies  itself  that  such
transaction is exempt from registration.  Neither the offering of the securities
nor any offering materials have been reviewed by an administrator  under the Act
or any applicable state law."

         The Company  need not effect a transfer of the  Securities,  unless the
conditions  specified in the  aforementioned  legend is  satisfied.  The Company
shall  also  make a  notation  on its  stock  transfer  books  of the  foregoing
restrictions on transferability  and will instruct its transfer agent, if one is
appointed,  not to register  the transfer of any of such  Securities  unless the
conditions specified in the foregoing legend are satisfied;

         2.15 CCL has full power and  authority  to  execute  and  deliver  this
Agreement.  This  Agreement has been duly and validly  executed and delivered by
CCL on  behalf of the  Investors  and  constitutes  a legal,  valid and  binding
obligation of CCL and the Investors  enforceable  in accordance  with its terms,
subject  to  bankruptcy,  insolvency,  reorganization,  and other  similar  laws
affecting the rights and remedies of creditors  generally and general principles
of equity; and

         2.16 The  execution  and  delivery  of this  Agreement,  and the terms,
conditions,  and  provisions of this Agreement will not conflict with, or result
in the breach of any term of, any corporate charter,  partnership agreement,  or
trust agreement,  or any indenture,  mortgage,  deed of trust, or other material
agreement  or  instrument  to  which  the  Investor  is a  party,  and  will not
constitute an event that, with the giving of notice,  lapse of time or any other
action by a third party,  could result in any default under any of the foregoing
that will result in the creation of any lien, charge,  encumbrance,  or security
interest upon the Securities.

         2.17 CCL  represents  the  holders  of  6,450,505  shares  of  Series A
Convertible Preferred Stock ("Series A") and the holders of Warrants to purchase
619,620  shares  of  Series A and is  authorized  to  consent  on behalf of such
holders to the issuance of the Shares,  the Warrants,  and the Series A issuable
on exercise of the Warrants,  and to waive the provisions of Section 3.2.2(b) of
the Company's Certificate of Designation dated August 28, 1998, as amended, with
respect to such issuance,  and hereby  consents to such issuance and waives such
provisions.


                                       4

<PAGE>


         III.  Representations and Warranties of A-Fem

         The Company represents and warrants to the Investors and to CCL that:

         3.1 The Company is a corporation  duly organized,  validly existing and
in good standing under the laws of Nevada and has the requisite  corporate power
and authority  necessary to own, lease and operate the properties it purports to
own, operate or lease and to carry on its business as it is now being conducted.
The  Company  is duly  qualified  or  licensed  as a foreign  corporation  to do
business,  and is in good standing,  in each jurisdiction where the character of
the properties  owned,  leased or operated by it or the nature of its activities
makes such qualification or licensing necessary,  except for such failures to be
so duly  qualified  or  licensed  and in good  standing  that would not,  either
individually  or in the  aggregate,  have a Material  Adverse  Effect.  The term
"Material  Adverse  Effect"  means any change or effect that is or is reasonably
likely to be materially  adverse to the business,  assets (including  intangible
assets), financial condition, results of operations, or prospects of the Company
taken as a whole.

         3.2 The Company has all  necessary  corporate  power and  authority  to
execute and deliver this Agreement and to perform its obligations  hereunder and
to consummate the transactions  contemplated  hereby. The execution and delivery
of this  Agreement  by the  Company  and the  consummation  of the  transactions
contemplated  hereby  have been duly and  validly  authorized  by all  necessary
corporate  action on the part of the Company and no other corporate  proceedings
on the part of the Company are  necessary  to  authorize  this  Agreement  or to
consummate the  transactions so  contemplated.  This Agreement has been duly and
validly   executed  and   delivered  by  the  Company  and,   assuming  the  due
authorization,  execution  and  delivery  by CCL  on  behalf  of the  Investors,
constitutes a legal, valid and binding obligation of the Company.

         3.3 The  execution  and delivery of this  Agreement by the Company does
not,  and the  performance  of this  Agreement  by the  Company  shall not,  (i)
conflict with or violate the Articles of Incorporation or Bylaws of the Company,
(ii)  conflict with or violate any law,  rule,  regulation,  order,  judgment or
decree applicable to the Company, or (iii) result in any breach of or constitute
a default under, or impair the Company's rights, or give to others any rights of
termination,  amendment,  acceleration  or  cancellation  of,  or  result in the
creation  of a lien or  encumbrance  on any of the  properties  or assets of the
Company pursuant to, any material note,  bond,  mortgage,  indenture,  contract,
agreement,  lease, license,  permit, franchise or other instrument or obligation
to which the  Company is a party or by which the Company or its  properties  are
bound or affected,  except for any such breaches,  defaults or other occurrences
that would  not,  individually  or in the  aggregate,  have a  Material  Adverse
Effect.


                                       5

<PAGE>


         3.4 The Company has filed all forms,  reports and documents required to
be filed with the SEC since June 30, 1993, and has  heretofore  delivered to CCL
in the form filed with the SEC, Annual Report on Form 10-KSB for the fiscal year
ended December 31, 1998,  and a Quarterly  Report on Form 10-QSB for each of the
fiscal quarters ended March 31, 1999 and June 30, 1999 (the "SEC Reports").  The
SEC Reports as amended (i) were prepared in accordance with the  requirements of
the Act or the Securities  Exchange Act of 1934, as amended, as the case may be,
and (ii) did not at the time they were filed (or if amended or  superseded  by a
filing  prior to the date of this  Agreement,  then on the date of such  filing)
contain any untrue statement of a material fact or omit to state a material fact
required  to be stated  therein  or  necessary  in order to make the  statements
therein,  in the light of the  circumstances  under  which they were  made,  not
misleading.  Except as  previously  disclosed to CCL,  since June 30, 1999,  the
Company has conducted  its business only in the ordinary  course of business and
in a manner  consistent  with past practice and, since such date,  there has not
been (i) any  change  in the  financial  condition,  results  of  operations  or
business of the Company having a Material Adverse Effect or, to the knowledge of
the  Company,  any  development  that could  reasonably  be  expected  to have a
Material  Adverse Effect,  other than as disclosed in the SEC Reports,  (ii) any
damage,  destruction or loss (whether or not covered by insurance)  with respect
to any assets of the  Company  having a Material  Adverse  Effect;  or (iii) any
declaration,  payment, or setting aside for payment of any dividends.  There are
no actions,  suits, or proceedings  pending or, to the knowledge of the Company,
threatened  against  the  Company,  nor is the  Company  subject  to any  order,
judgment, or decree that would have a Material Adverse Effect.

         3.5 The Securities,  when issued, sold and delivered in accordance with
the  terms  hereof  for the  consideration  expressed  herein,  will be duly and
validly  issued,  fully  paid  and  nonassessable  and  free  of  any  liens  or
encumbrances  created by the Company and free of any restrictions  imposed under
the Nevada Control Share  Acquisition  Act and the issuance of the Securities is
not a prohibited  transaction  under the Nevada  Business  Combination  Act. The
issuance of the  Securities  will not  constitute a change in control  under any
agreement applicable to the Company,  including an agreement between the Company
and Proctor & Gamble.

         IV.      Supersedes Prior Negotiation

         This Purchase  Agreement  supersedes in its entirety prior negotiations
with CCL concerning an investment in the Company.

                                       6

<PAGE>


         V.       Counterparts

         This Agreement may be executed in any number of counterparts,  and each
such  counterpart  shall  be  deemed  to be an  original  instrument.  All  such
counterparts together shall constitute one agreement.


         [this space intentionally left blank]

                                       7

<PAGE>


         IN WITNESS  WHEREOF,  the Investor and the Company have  executed  this
Purchase Agreement dated effective as of September 22, 1999.

                                        CAPITAL CONSULTANTS LLC
                                        as Agent for the Investors


                                        /s/ Barclay L. Grayson
                                        ---------------------------------
                                        By:  Barclay L. Grayson
                                        Its: President

                                        Address: 2300 SW First Avenue
                                                 Portland, OR 97201


                                        A-FEM MEDICAL CORPORATION

                                        /s/ Steven T. Frankel
                                        ---------------------------------
                                        By:  Steven T. Frankel
                                        Its: Chief Executive Officer and
                                             President

                                        Address: A-FEM Medical Corporation
                                                 Suite J-5
                                                 10180 S.W. Nimbus Avenue
                                                 Portland, OR  97223


                                       8

<PAGE>



                                     Rider A

                            A-FEM MEDICAL CORPORATION

                                   SCHEDULE 1

         Per Section 2.12 of the A-Fem Medical  Corporation  Preferred Stock and
Warrant  Purchase  Agreement dated September 22, 1999,  Capital  Consultants LLC
represents   that  each   Investor  is  a  resident  of  one  of  the  following
jurisdictions:

         Oregon

         Washington

         Idaho

         Texas

         New Mexico

         Arizona

         Colorado

         Nevada

                                       9

<PAGE>


                                    Exhibit C

THIS  WARRANT  HAS NOT BEEN  REGISTERED  UNDER THE  SECURITIES  ACT OF 1933,  AS
AMENDED  (THE "ACT"),  OR  APPLICABLE  STATE LAW, AND NO INTEREST  HEREIN MAY BE
SOLD, DISTRIBUTED,  ASSIGNED,  OFFERED,  PLEDGED OR OTHERWISE TRANSFERRED UNLESS
(i) THERE IS AN EFFECTIVE  REGISTRATION  STATEMENT  UNDER THE ACT AND APPLICABLE
STATE SECURITIES LAWS COVERING ANY SUCH  TRANSACTION  INVOLVING SAID SECURITIES,
(ii) THIS  CORPORATION  RECEIVES  AN OPINION OF LEGAL  COUNSEL FOR THE HOLDER OF
THESE SECURITIES  SATISFACTORY TO THIS CORPORATION STATING THAT SUCH TRANSACTION
IS EXEMPT  FROM  REGISTRATION,  OR (iii) THIS  CORPORATION  OTHERWISE  SATISFIES
ITSELF THAT SUCH TRANSACTION IS EXEMPT FROM REGISTRATION.


No. 99P-14                                   WARRANT TO PURCHASE SHARES OF
                                             CONVERTIBLE PREFERRED STOCK


                             STOCK PURCHASE WARRANT

                              TO PURCHASE SHARES OF
                         CONVERTIBLE PREFERRED STOCK OF
                            A-FEM MEDICAL CORPORATION

         For value  received as set forth in that  certain  Preferred  Stock and
Warrant  Purchase  Agreement  between certain  investors (each an "Investor" and
collectively,  the "Investors") acting through their agent,  Capital Consultants
LLC ("CCL"), and A-Fem Medical Corporation, a Nevada corporation (the "Company")
dated September 22, 1999, the Company grants to Capital Consultants LLC as Agent
for Client No. 518-88, the Holder, as hereinafter defined, the right, subject to
the terms of this Warrant,  to purchase 52,080 shares of the Company's  Series A
Convertible  Preferred  Stock,  par value $.01 per share,  at $.01 per share, as
adjusted (the "Exercise Price") .

         Section 1  Definitions.

         As used in this Warrant, unless the context otherwise requires:

         1.1.  "Exercise Date" means any date when this Warrant is exercised in
the manner indicated in Sections 2.1 and 2.2.

         1.2.  "Expiration Date" means 5:00 p.m. Pacific Time, ten years from
the date hereof.

                                       1

<PAGE>


         1.3.  "Holder" means (i) CCL, as agent for any Investor it represents
and (ii) each Investor.

         1.4.  "Securities Act" means the Securities Act of 1933, as amended
from time to time, and all rules and regulations promulgated thereunder,  or any
act, rules or  regulations  that  replace  the  Securities  Act or any such
rules and regulations.

         1.5. "Preferred Stock" means shares of the class designated as Series A
Convertible Preferred Stock, par value $.01 per share, of the Company.

         1.6. "Common Stock" means shares of the class designated as Common
Stock, par value $.01 per share, of the Company.

         1.7. "Warrant Shares" means any shares of Preferred Stock issued or
issuable upon exercise of this Warrant.

         Section 2  Duration and Exercise of Warrant.

         2.1  Exercise Period

         Subject to the provisions of Sections 2.4, 4 and 6 hereof, this Warrant
may be exercised,  in whole or in part, during the period commencing on the date
two years after the date  hereof and ending on the  Expiration  Date.  After the
Expiration  Date this  Warrant  shall  become  void,  and all rights to purchase
Warrant Shares hereunder shall thereupon cease.

         2.2      Method of Exercise

         This Warrant may be exercised  by the Holder,  in whole or in part,  by
(i) surrendering this Warrant to the Secretary of the Company, (ii) tendering to
the Company payment in full by cash or by check acceptable to the Company of the
Exercise  Price for the  Warrant  Shares  for which  exercise  is made and (iii)
executing and  delivering  to the Secretary of the Company an Exercise  Form, in
the form attached to this Warrant.

         Upon exercise, the Holder shall be deemed to be the holder of record of
the  Warrant  Shares for which  exercise is made,  even  though the  transfer or
registrar books of the Company may then be closed or  certificates  representing
such Warrant Shares may not then be actually delivered to the Holder.

         No fractional shares or scrip  representing  fractional shares shall be
issued upon the exercise of this  Warrant.  In lieu of any  fractional  share to
which the Holder would otherwise be entitled, the Company shall round up or down
the number of shares to the nearest whole share.

                                       2

<PAGE>


         2.3   Certificates

         As soon as practicable  after the exercise,  at the Company's  expense,
certificates  for such  Warrant  Shares  shall be  delivered  to the Holder and,
unless this Warrant has expired,  a warrant  representing  the number of Warrant
Shares, if any, with respect to which this Warrant shall not have been exercised
shall be issued to the Holder.

         2.4   Securities Act Compliance

         Unless the transfer of the Warrant  Shares  shall have been  registered
under the Securities Act, as a condition of the delivery of certificates for the
Warrant Shares, the Company may require the Holder to deliver to the Company, in
writing,  representations  regarding  the  Holder's  sophistication,  investment
intent,  acquisition  for  Holder's  own account  and such other  matters as are
reasonable and customary for purchasers of securities in an unregistered private
offering.  The Company may place  conspicuously  upon each Warrant and upon each
certificate  representing  the  Warrant  Shares  a legend  substantially  in the
following form, the terms of which are agreed to by the Holder:

         "THESE  SECURITIES HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF
1933, AS AMENDED (THE "ACT"),  OR APPLICABLE  STATE LAW, AND NO INTEREST THEREIN
MAY BE SOLD, DISTRIBUTED,  ASSIGNED,  OFFERED,  PLEDGED OR OTHERWISE TRANSFERRED
UNLESS  (i)  THERE IS AN  EFFECTIVE  REGISTRATION  STATEMENT  UNDER  THE ACT AND
APPLICABLE STATE  SECURITIES LAWS COVERING ANY SUCH  TRANSACTION  INVOLVING SAID
SECURITIES,  (ii) THIS CORPORATION  RECEIVES AN OPINION OF LEGAL COUNSEL FOR THE
HOLDER OF THESE SECURITIES  SATISFACTORY TO THIS  CORPORATION  STATING THAT SUCH
TRANSACTION IS EXEMPT FROM  REGISTRATION,  OR (iii) THIS  CORPORATION  OTHERWISE
SATISFIES ITSELF THAT SUCH TRANSACTION IS EXEMPT FROM REGISTRATION."

         2.5   Taxes

         The Company shall not be required to pay any tax that may be payable in
respect of any transfer of this Warrant.

                                       3

<PAGE>



         Section 3  Validity and Reservation of Warrant Shares.

         The Company  covenants  that all shares of Preferred  Stock issued upon
exercise of this Warrant,  pursuant to the terms and conditions herein,  will be
validly issued,  fully paid,  nonassessable and free of preemptive  rights.  The
Company agrees that, as long as this Warrant may be exercised,  the Company will
reserve from its authorized and unissued  Preferred Stock a sufficient number of
shares to provide for the issuance of the Preferred  Stock upon exercise of this
Warrant  (and  shares of its Common  Stock for  issuance on  conversion  of such
Preferred Stock).

         Section 4  Limited Rights of Warrant Holder.

         The  Holder  shall  not,  solely by virtue of being the  Holder of this
Warrant,  have any of the rights of a holder of Preferred  Stock of the Company,
either at law or equity,  until such Warrant  shall have been  exercised and the
Holder shall be deemed to be the holder of record of Warrant  Shares as provided
in this  Warrant,  at  which  time  the  person  or  entity  in  whose  name the
certificate  for Warrant Shares being  purchased is to be issued shall be deemed
the holder of record of such shares for all purposes.

         Section 5  Loss of Warrant.

         Upon receipt by the Company of reasonably  satisfactory evidence of the
loss,  theft,  destruction or mutilation of this Warrant and either (in the case
of  loss,  theft  or  destruction)   reasonable   indemnification   and  a  bond
satisfactory  to the  Company  if  requested  by the  Company or (in the case of
mutilation)  the  surrender of this Warrant for  cancellation,  the Company will
execute and deliver to the Holder,  without charge,  a new Warrant of like tenor
and amount.

         Section 6  Adjustments.

         The  Exercise  Price and the  number of shares  purchasable  under this
Warrant are subject to adjustment from time to time as follows:

         6.1   Merger, Sale of Assets, etc.

         If at  any  time  while  this  Warrant,  or  any  portion  thereof,  is
outstanding  and  unexpired  there  shall  be a  reorganization  (other  than  a
combination,  reclassification,  exchange or subdivision of shares  provided for
herein),   merger  or   consolidation  of  the  Company  with  or  into  another
corporation,  or  the  sale  or  transfer  of all  or  substantially  all of the
Company's  properties  and assets to any other  person,  then, as a part of such
reorganization, merger, consolidation, transfer or sale, provision shall be made
so that the Holder of this Warrant shall  thereafter be entitled to  immediately
exercise  this Warrant and to receive upon  exercise of this  Warrant,  and upon
payment

                                       4

<PAGE>



of the  Exercise  Price then in  effect,  the number of shares of stock or other
securities or property of the Company, or of the successor corporation resulting
from such reorganization,  merger,  consolidation,  transfer or sale, to which a
holder of the shares  deliverable  upon exercise of this Warrant would have been
entitled to receive in such reorganization,  merger,  consolidation or sale, all
subject to adjustment as provided herein.

         6.1   Reclassification, etc.

         If the Company,  at any time while this Warrant or any portion  hereof,
remains   outstanding  and  unexpired  by   reclassification  of  securities  or
otherwise,  shall change any of the securities as to which purchase rights under
this  Warrant  exist into the same or a different  number of  securities  of any
other class or classes,  this Warrant  shall  thereafter  represent the right to
acquire such number and kind of  securities  as would have been  issuable as the
result of such change with  respect to the  securities  that were subject to the
purchase rights under this Warrant immediately prior to such reclassification or
other change and the Exercise Price thereof shall be appropriately adjusted, all
subject to further adjustments as provided in this Section.

         6.3   Split, Subdivision or Combination of Shares.

         If the Company at any time while this Warrant,  or any portion  hereof,
remains  outstanding  and  unexpired  shall  split,  subdivide  or  combine  the
securities  as to  which  purchase  rights  under  this  Warrant  exist,  into a
different  number of securities of the same class,  the Exercise  Price for such
securities  shall  be  proportionately  decreased  in the  case  of a  split  or
subdivision or proportionately increased in the case of a combination.

         6.4   Adjustments for Dividends in Stock or Other Securities or
               Property.

         If while this Warrant,  or any portion hereof,  remains outstanding and
unexpired,  the holders of the securities as to which purchase rights under this
Warrant  exist at the time shall have  received,  or on or after the record date
for the  determination of eligible  shareholders,  shall have become entitled to
receive,  without  payment  therefore,   other  or  additional  stock  or  other
securities or property (other than cash) of the Company by way of dividend, then
and in each such case,  this Warrant shall  represent  the right to acquire,  in
addition to the number of shares of the  security  receivable  upon  exercise of
this Warrant, and without payment of any additional  consideration therefor, the
amount of such other or additional  stock or other securities or property (other
than  cash) of the  Company  that  such  holder  would  hold on the date of such
exercise  had it been the  holder  of  record of the  security  receivable  upon
exercise  of this  Warrant  on the date  hereof and had  thereafter,  during the
period from the date hereof to and including the date of such exercise, retained
such shares and/or

                                       5

<PAGE>



all other  additional  stock  available by it as  aforesaid  during such period,
giving effect to all adjustment  called for during such period by the provisions
of this Section 6.

         6.5   Certificate of Adjustments.

         Upon the occurrence of each adjustment or readjustment pursuant to this
Section 6, the Company,  at its expense,  shall promptly compute such adjustment
or readjustment in accordance with the terms hereof and furnish to the Holder of
this Warrant a certificate,  signed by the Chairman of the Board,  the President
or the Chief  Financial  Officer,  setting forth such adjustment or readjustment
and showing in detail the facts upon which such  adjustment or  readjustment  is
based.  The  Company  shall,  upon the  written  request at any time of any such
Holder,  furnish or cause to be furnished to such Holder a  certificate  setting
forth:  (A) such  adjustments and  readjustments,  (B) the Exercise Price at the
time in effect  and (C) the number of shares and the  amount,  if any,  of other
property that at the time would be received upon the exercise of the Warrant.

         6.6   No Impairment.

         The Company will not, by any voluntary  action,  avoid or seek to avoid
the  observance or  performance  of any of the terms to be observed or performed
hereunder  by the  Company,  but will at all times in good  faith  assist in the
carrying  out of all the  provisions  of this Section 6 and in the taking of all
such action as may be necessary or appropriate in order to protect the rights of
the Holder of this Warrant against impairment.

         Section 7  Registration Rights.

         Upon exercise of this Warrant, the Holder shall have and be entitled to
exercise,  together with all other holders of Registrable  Securities possessing
registration  rights under that certain  A-Fem Medical  Corporation  Amended and
Restated  Registration  Rights  Agreement,  of even date  herewith,  between the
Company and CCL  ("Investors'  Rights  Agreement"),  the rights of  registration
granted under the Investors'  Rights  Agreement to Registrable  Securities (with
respect to the shares of common stock issuable upon  conversion of the Preferred
Stock issuable upon exercise of this  Warrant).  By its receipt of this Warrant,
Holder agrees to be bound by the Investors' Rights Agreement.

                                       6

<PAGE>



         Section 8  Miscellaneous.

         8.1   Successors and Assigns

         All the covenants and provisions of this Warrant that are by or for the
benefit of the Company shall bind and inure to the benefit of its successors and
assigns hereunder.

         8.2   Notice

         Any notice or demand pursuant to this Warrant shall be given in writing
and shall be deemed  effectively given upon personal delivery to the party to be
notified or three days  following  deposit  with the United  States Post Office,
postage  prepaid,  registered  or certified  with return  receipt  requested and
addressed to the party to be notified as provided below:

         If to the Company:         A-Fem Medical Corporation
                                    Suite J-5
                                    10180 S.W. Nimbus Avenue
                                    Portland, OR  97223
                                    (503) 968-8800

         If to the Holder:          Capital Consultants LLC
                                    Suite 200
                                    2300 SW First Ave.
                                    Portland, OR  97201

         Each party may specify a different  address  than set forth above by 10
days' advance notice thereof given in the foregoing manner.

         8.3   Applicable Law

         The validity,  interpretation  and performance of this Warrant shall be
governed  by the laws of the State of  Oregon as  applied  to  agreements  among
Oregon residents  entered into and to be performed  entirely within the State of
Oregon.

         8.4   Headings

         The Article  headings herein are for convenience  only and are not part
of this Warrant and shall not affect the interpretation thereof.

         8.5   Amendments; Waiver

         This Warrant and any term hereof may be changed, waived,  discharged or
terminated only by an instrument in writing signed by the party against which

                                       7

<PAGE>



enforcement  of such change,  waiver,  discharge or  termination  is sought.  No
waivers of, or exceptions  to any term,  condition or provision of this Warrant,
in any one or more instances,  shall be deemed to be, or construed as, a further
or continuing waiver of any such term, condition or provision.

         Dated:  September 22, 1999

                                     A-FEM MEDICAL CORPORATION



                                     By:  /s/ Steven T. Frankel
                                          --------------------------
                                          Steven T. Frankel
                                          Chief Executive Officer and President


                                      8
<PAGE>


                                  EXERCISE FORM

                          (To Be Executed by the Holder
                  to Exercise the Warrant in Whole or in Part)

To:      A-FEM MEDICAL CORPORATION


         I, the undersigned,  hereby  irrevocably elect to exercise the right of
purchase represented by Warrant No. ____ for, and to purchase thereunder, ______
shares of Series A Convertible  Preferred Stock for a purchase price of $.01 per
share, as provided for therein.

         I  hereby  tender  payment  herewith  to the  order  of  A-FEM  MEDICAL
CORPORATION in the amount of $ _________.

         I request  that  certificates  for such shares of Series A  Convertible
Preferred Stock be issued and delivered as stated below,  and, if said number of
shares of Series A  Convertible  Preferred  Stock shall not be all the shares of
Series A Convertible Preferred Stock purchasable thereunder,  that a new Warrant
for the balance remaining of the shares of Series A Convertible  Preferred Stock
purchasable  under the within  Warrant be  registered  and  delivered  to me, as
stated below:

Signature:
               -----------------------------------------------------------
Name:
               -----------------------------------------------------------
Address:
               -----------------------------------------------------------
Deliver to:
               -----------------------------------------------------------
Address:
               -----------------------------------------------------------

         Note:  Signature must correspond with the name as written upon the face
of the Warrant in every particular, without alteration or enlargement or any
change whatsoever.


                                       9

<PAGE>


                                    Exhibit D
                            A-FEM MEDICAL CORPORATION
               AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT


         This Amended and Restated Registration Rights Agreement is entered into
as of the 22nd day of September, 1999, by and between A-Fem Medical Corporation,
a Nevada corporation  ("A-Fem"),  and Capital Consultants LLC, an Oregon limited
liability company, as agent for certain investors it represents (in its capacity
as agent,  Capital  Consultants LLC is referred to herein as "CCL") and replaces
and supersedes those certain  Registration Rights Agreements entered into by and
between A-Fem and CCL dated as of August 31, 1998, October 8, 1998,  November 6,
1998, March 9, 1999, April 15, 1999, May 10, 1999, June 15, 1999, July 21, 1999,
and August 19, 1999.

         The parties agree as follows:

         1.    Definitions

         1.1 The  terms  "Form  S-1,"  "Form  S-2"  and  "Form  S-3"  mean  such
respective  forms under the Securities Act of 1933, as amended ("the 1933 Act"),
as in effect on the date hereof or any successor registration forms to Form S-1,
Form S-2 and Form S-3, respectively,  under the 1933 Act subsequently adopted by
the Securities  and Exchange  Commission or any other federal agency at the time
administering the 1933 Act (the "SEC").

         1.2 The terms "register,"  "registered," and "registration"  refer to a
registration  effected  by  preparing  and filing a  registration  statement  or
similar document in compliance with the 1933 Act and the declaration or ordering
of effectiveness of such registration statement or document.

         1.3 The term  "Registrable  Securities"  means the shares of the common
stock of A-Fem (the "Common  Stock") to be issued upon  conversion of the shares
of convertible  preferred stock (the "Preferred Stock") to be issued pursuant to
(i) the Preferred  Stock and Warrant  Purchase  Agreement dated as of August 31,
1998, (ii) the Plan and Agreement for Recapitalization  dated as of September 1,
1998, (iii) the Stock Purchase Warrant (No. 98P-1) to purchase 130,000 shares of
Preferred Stock,  (iv) the Preferred Stock and Warrant Purchase  Agreement dated
as of October 8, 1998,  (v) the Stock Purchase  Warrant (No.  98P-3) to purchase
127,280 shares of Preferred  Stock,  (vi) the Stock Purchase Warrant (No. 98P-4)
to purchase  72,720 shares of Preferred  Stock,  (vii) the  Preferred  Stock and
Warrant  Purchase  Agreement  dated as of  November  6,  1998,  (viii) the Stock
Purchase Warrant (No. 98P-5) to purchase

                                       1

<PAGE>


102,065 shares of Preferred  Stock,  (ix) the Stock Purchase Warrant (No. 98P-6)
to purchase 1,583 shares of Preferred Stock, (x) the Stock Purchase Warrant (No.
98P-7) to purchase 552 shares of Preferred  Stock,  (xi) the Preferred Stock and
Warrant  Purchase  Agreement dated as of March 9, 1999, (xii) the Stock Purchase
Warrant (No.  99P-8) to purchase  31,250 shares of Preferred  Stock,  (xiii) the
Preferred Stock and Warrant Purchase Agreement dated as of April 15, 1999, (xiv)
the Stock Purchase  Warrant (No.  99P-9) to purchase  20,834 shares of Preferred
Stock,  (xv) the Preferred Stock and Warrant Purchase  Agreement dated as of May
10,  1999,  (xvi) the Stock  Purchase  Warrant (No.  99P-10) to purchase  20,834
shares of  Preferred  Stock,  (xvii) the  Preferred  Stock and Warrant  Purchase
Agreement  dated as of June 15, 1999,  (xviii) the Stock  Purchase  Warrant (No.
99P-11) to purchase 20,834 shares of Preferred Stock,  (xix) the Preferred Stock
and  Warrant  Purchase  Agreement  dated as of July  21,  1999,  (xx) the  Stock
Purchase  Warrant (No.  99P-12) to purchase  20,834  shares of Preferred  Stock,
(xxi) the Preferred Stock and Warrant Purchase  Agreement dated August 19, 1999,
(xxii) the Stock  Purchase  Warrant (No.  99P-13) to purchase  20,834  shares of
Preferred  Stock,  (xxiii) the Preferred  Stock and Warrant  Purchase  Agreement
dated as of  September  22,  1999,  and (xxiv) the Stock  Purchase  Warrant (No.
99P-14) to purchase  52,080  shares of  Preferred  Stock,  and any Common  Stock
issued  as a  dividend  or other  distribution  with  respect  to,  or any other
securities  issued in exchange for, or in replacement  of, such shares of Common
Stock. As to any particular Registrable  Securities,  such securities will cease
to be  Registrable  Securities  when (i) they have been  effectively  registered
under the 1933 Act and disposed of in accordance with the registration statement
covering  them, or (ii) they may be sold by a Holder  without  effective  volume
limitations  pursuant  to Rule 144 (or any similar  provision  that is in force)
under the 1933 Act.

         1.4 The term  "Holder"  means  (i)  CCL,  provided  that it  holds  any
Registrable Securities as agent for any investor it represents, (ii) each of the
investors for whom CCL holds the  Registrable  Securities and (iii) any assignee
in accordance with Section 9.

         2.    Registration Rights

         2.1   Demand Registration Rights

                  (a) If the Company shall  receive,  at any time after the date
hereof,  a written  request from the Holders of at least 30% of the  Registrable
Securities then outstanding  (the "Initiating  Holders") that the Company file a
registration  statement  under the Securities Act covering the  registration  of
such Initiating Holders' Registrable Securities,  then the Company shall, within
five days after the receipt of such request, give written notice of such request
to all Holders and shall, subject to


                                       2

<PAGE>


the  limitations  set  forth  below,  use its  best  efforts  to file as soon as
practicable,   a  registration   statement  under  the  Securities  Act  of  all
Registrable  Securities  that the Holders  request to be registered in a written
request  to be given  within  five  days of the  mailing  of such  notice by the
Company, and shall use its best efforts to cause such registration  statement to
be declared effective as soon as practicable.

                  (b) The Company is obligated to effect only two  registrations
pursuant to this Section 2.1; provided, however, that if the Company is eligible
to register  securities  on Form S-3,  then the Company is obligated to effect a
registration  on such Form S-3 each time such  registration  is requested by the
Holders pursuant to this Section 2.1.

                  (c)  Notwithstanding  the  foregoing,  if  the  Company  shall
furnish to the Holders requesting a registration  pursuant to this Section 2.1 a
certificate  signed by the  President of the Company  stating  that, in the good
faith  judgment of the Board of Directors of the Company,  it would be seriously
detrimental to the Company and its shareholders for such registration  statement
to be  filed  and  it is  therefore  essential  to  defer  the  filing  of  such
registration  statement,  the Company  shall have the right to defer such filing
for not  more  than 60 days  after  receipt  of the  request  of the  Initiating
Holders.

                  (d)  Subject  to  Section  2.1(c),  if  the  Company  fails to
file  a  registration  statement  within 20 business  days after  receipt of the
request of the Initiating Holders ("Deadline"),  then the Company  will grant to
the Holders requesting registration ten-year warrants, with an exercise price of
$1.92 per share, to purchase the number of shares of common stock of the Company
determined by the product of (1) number of days elapsed between the Deadline and
the date the  registration  statement  is filed;  and (2) 1% of the  Registrable
Shares that the Holders  requested to be  registered.  The warrants will contain
terms,  conditions and adjustments  similar to warrants previously issued to the
Holders,  and the  warrant  will be  issued  within  30  days  of the  date  the
registration  statement  is filed.  No such warrant will be issued to any Holder
who fails to promptly supply  information  concerning such Holder to be included
in the Registration Statement.

         2.2   Incidental Registration Rights

                  (a) If at any time after the date  hereof  A-Fem  proposes  to
register any of its securities  under the 1933 Act (except for  registration  of
shares  solely  in  connection  with an  employee  benefit  plan or a merger  or
consolidation)  in any  public  offering,  whether  or not for  sale for its own
account,  it will at such  time  give  prompt  written  notice  to Holder of its
intention to do so and of Holder's rights under this Section 2.

                                       3

<PAGE>



                  (b) Upon the  written  request of Holder  made  within 30 days
after the receipt of any such notice (which  request shall specify the number of
Registrable Securities intended to be disposed of by Holder), A-Fem will use its
best efforts to effect the registration  under the 1933 Act and applicable state
securities laws of all Registrable Securities in connection therewith that A-Fem
has been so requested to register by Holder.

                  (c) If the managing underwriter for any underwritten  offering
in a registration pursuant to this Section 2.2 shall inform in writing A-Fem and
Holder of its belief that the number of  securities  requested to be included in
such  registration  would  materially and adversely affect its ability to effect
such  offering,  then A-Fem will  include in such  registration  the number that
A-Fem is so advised can be sold in (or during the time of) such offering, first,
all  securities  proposed by A-Fem to be sold for its own  account,  and second,
such  Registrable  Securities  and other  securities  of A-Fem  requested  to be
included  in  such   registration  by  persons   exercising   their   incidental
registration  rights,  pro rata on the  basis of the  number  of  shares of such
securities so proposed to be sold and so requested to be included.

         3.    Obligations of A-Fem

         Whenever  required  under  this  Agreement  to use its best  efforts to
effect the registration of Registrable Securities, A-Fem shall, as expeditiously
as possible:

         3.1 Prepare and file with the SEC a registration statement with respect
to  such  Registrable  Securities  and  use  its  best  efforts  to  cause  such
registration  statement  to become  and remain  effective  for the period of the
distribution contemplated thereby determined as provided hereafter.

         3.2 Prepare and file with the SEC such  amendments  and  supplements to
such  registration  statement and the  prospectus  used in connection  with such
registration  statement as may be necessary to comply with the provisions of the
1933 Act with  respect  to the  disposition  of all  securities  covered by such
registration statement.

         3.3 Furnish to Holder such reasonable number of copies of a prospectus,
including any preliminary prospectus, in conformity with the requirements of the
1933 Act, and any amendments or supplements  thereto and such other documents as
Holder  may  reasonably  request  in  order to  facilitate  the  disposition  of
Registrable Securities owned by Holder.

         3.4 Use its best efforts to register and qualify the securities covered
by such  registration  statement under such other securities or Blue Sky laws of
all 50 states,

                                       4

<PAGE>



provided that the Company shall not be required in connection  therewith or as a
condition  thereto  to qualify to do  business  or to file a general  consent to
service of process in any such states.

         3.5 In the event of any underwritten  public  offering,  enter into and
perform its obligations under an underwriting  agreement, in usual and customary
form,  with the managing  underwriter of such offering.  Holder shall also enter
into and perform its obligations under such an agreement,  including  furnishing
any opinion of counsel or entering into a lock-up agreement reasonably requested
by the  managing  underwriter  and take such  other  actions  as are  reasonably
required in order to expedite or facilitate the  disposition of the  Registrable
Securities to be so included in the registration statement.

         3.6  Notify  Holder,  at any time when a  prospectus  relating  thereto
covered by such  registration  statement is required to be  delivered  under the
1933 Act,  of the  happening  of any  event as a result of which the  prospectus
included in such registration  statement,  as then in effect, includes an untrue
statement of a material  fact or omits to state a material  fact  required to be
stated therein or necessary to make the statements therein not misleading in the
light of the  circumstances  then existing and promptly file such amendments and
supplements  that may be  required  on  account  of such  event and use its best
efforts to cause each such amendment and supplement to become effective.

         3.7 Furnish,  at the request of any Holder  requesting  registration of
Registrable  Securities pursuant to Section 2, on the date that such Registrable
Securities  are  delivered to the  underwriters  for sale in  connection  with a
registration  pursuant to Section 2, if such  securities  are being sold through
underwriters, or, if such securities are not being sold through underwriters, on
the date that the registration statement with respect to such securities becomes
effective,  (i) an opinion,  dated such date,  of the counsel  representing  the
Company  for the  purposes of such  registration,  in form and  substance  as is
customarily given to underwriters in an underwritten public offering,  addressed
to the  underwriters,  if any,  and to the Holders  requesting  registration  of
Registrable  Securities and (ii) a letter dated such date,  from the independent
certified  public  accountants  of the  Company,  in form  and  substance  as is
customarily given by independent certified public accountants to underwriters in
an underwritten public offering,  addressed to the underwriters,  if any, and to
the Holders requesting registration of Registrable Securities.

         3.8 Otherwise use its best efforts to comply with all applicable  rules
and regulations of the SEC, and make available to its security holders,  as soon
as reasonably practicable, but not later than 18 months after the effective date
of the

                                       5

<PAGE>



registration statement, an earnings statement covering the period of at least 12
months  beginning  with the first full month  after the  effective  date of such
registration statement, which earnings statement shall satisfy the provisions of
Section 11(a) of the Securities Act.

         3.9 Use its best efforts to list the Restricted  Securities  covered by
such  registration  statement with any  securities  exchange on which the Common
Stock of the Company is then listed.

         For  purposes of Sections 3.1 and 3.2,  the period of  distribution  of
Registrable  Securities in a firm commitment  underwritten public offering shall
be deemed to extend until each underwriter has completed the distribution of all
securities  purchased  by it,  and the  period of  distribution  of  Registrable
Securities in any other registration shall be deemed to extend until the earlier
of the sale of all Registrable Securities covered thereby and one year after the
effective date thereof.

         4.    Preparation; Information; Reasonable Investigation

         4.1   Furnish Information

         It shall be a condition  precedent to the  obligations of A-Fem to take
any action  pursuant to this  Agreement  that Holder shall furnish to A-Fem such
information regarding Holder, the Registrable Securities held by Holder, and the
intended method of disposition of such securities as shall be required to effect
the registration of Holder's Registrable Securities.

         4.2   Preparation; Reasonable Investigation

         In  connection  with the  preparation  and  filing of any  registration
statement under the 1933 Act pursuant to this Agreement,  A-Fem will give Holder
and Holder's counsel, accountants or underwriters the opportunity to participate
in the preparation of such  registration  statement,  each  prospectus  included
therein or filed with the SEC, and each amendment thereof or supplement thereto,
and will give Holder such access to its books and records and such opportunities
to discuss the business of A-Fem with its officers  and the  independent  public
accountants  who have certified its financial  statements as shall be necessary,
in the opinion of Holder's  counsel,  accountants or underwriters,  to conduct a
reasonable investigation within the meaning of the 1933 Act.

                                       6

<PAGE>



         5.    Expenses of Registration

         All expenses  (other than  underwriting  discounts and  commissions and
transfer  taxes,  if  any)  relating  to  Registrable   Securities  incurred  in
connection with the  registrations,  filings or qualifications  pursuant to this
Agreement,   including   without   limitation  all   registration,   filing  and
qualification  fees,  printing and accounting  fees, fees and  disbursements  of
counsel for A-Fem,  and fees and  disbursements  of counsel to Holder,  shall be
borne by A-Fem.

         6.    Indemnification

         If any Registrable  Securities are included in a registration statement
under this Agreement:

         6.1   A-Fem Indemnification

         To the extent  permitted by law, A-Fem will indemnify and hold harmless
and defend Holder, the officers,  directors,  partners,  agents and employees of
Holder or any underwriter (as defined in the 1933 Act), and each person, if any,
who  controls  Holder or  underwriter  within the meaning of the 1933 Act or the
Securities  Exchange  Act of 1934,  as amended  (the "1934  Act"),  against  any
losses,  claims,  damages or  liabilities  (joint or  several) to which they may
become  subject  under the 1933 Act, the 1934 Act or other federal or state law,
insofar as such losses,  claims,  damages or liabilities  (or actions in respect
thereof)  arise  out of or are  based  upon  any  of the  following  statements,
omissions or violations (a "Violation"):

                  (i) any untrue  statement  or alleged  untrue  statement  of a
material  fact  contained  in  such   registration   statement,   including  any
preliminary  prospectus or final prospectus  contained therein or any amendments
or supplements thereto,

                  (ii) the  omission  or  alleged  omission  to state  therein a
material fact required to be stated  therein or necessary to make the statements
therein not misleading, or

                  (iii) any violation or alleged  violation by A-Fem of the 1933
Act,  the  1934  Act,  any  state  securities  law or  any  rule  or  regulation
promulgated under the 1933 Act, the 1934 Act or any state securities law.

         A-Fem will pay or reimburse such Holder,  officer,  director,  partner,
agent,  employee,  underwriter,  or  controlling  person  for any legal or other
expenses  reasonably  incurred  by  them in  connection  with  investigating  or
defending any such loss, claim, damage,

                                       7

<PAGE>


liability or action. The indemnity agreement contained in this Section 6.1 shall
not apply to amounts paid in settlement of any loss, claim, damage, liability or
action if such  settlement  is  effected  without  the  consent of A-Fem  (which
consent shall not be unreasonably withheld), nor shall A-Fem be liable to Holder
in any such case for any such loss,  claim,  damage,  liability or action (a) to
the extent that it arises  solely from or is based solely upon a Violation  that
occurs in reliance upon and in  conformity  with written  information  furnished
expressly for use in connection with such registration by or on behalf of Holder
or its  controlling  person,  or (b) if such untrue  statement or alleged untrue
statement  or  omission  or alleged  omission  was  contained  in a  preliminary
prospectus and corrected in a final or amended prospectus,  and Holder failed to
deliver  a  copy  of  the  final  or  amended  prospectus  at or  prior  to  the
confirmation of the sale of the Registrable  Securities to the person  asserting
any such loss,  claim,  damage or liability  in any case where such  delivery is
required by the 1933 Act.

         6.2   Holder Indemnification

         To the extent permitted by law, Holder will indemnify and hold harmless
A-Fem,  each  of its  directors,  each  of its  officers  who  have  signed  the
registration  statement,  and each person, if any, who controls A-Fem within the
meaning of the 1933 Act,  against any  losses,  claims,  damages or  liabilities
(joint or several) to which A-Fem or any such  director,  officer or controlling
person,  under the 1933 Act, the 1934 Act or other federal or state law, insofar
as such losses,  claims,  damages or liabilities (or actions in respect thereto)
arise out of or are based upon any  Violation,  in each case to the extent  (and
only  to the  extent)  that  such  Violation  occurs  in  reliance  upon  and in
conformity  with  written  information  furnished  by or  on  behalf  of  Holder
expressly  for  use in  connection  with  such  registration;  and  Holder  will
reimburse any legal or other expenses  reasonably  incurred by A-Fem or any such
director,  officer or controlling  person,  in connection with  investigating or
defending any such loss, claim, damage, liability or action; provided,  however,
that the  indemnity  agreement  contained in this Section 6.2 shall not apply to
amounts paid in settlement of any such loss, claim, damage,  liability or action
if such  settlement  is effected  without the consent of Holder,  which  consent
shall not be unreasonably withheld, nor, in the case of a sale directly by A-Fem
of its securities  (including a sale of such securities  through any underwriter
retained by A-Fem to engage in a distribution solely on behalf of A-Fem),  shall
Holder be liable to A-Fem in any case in which such untrue statement or omission
or alleged untrue  statement or alleged  omission was contained in a preliminary
prospectus and corrected in a final or amended  prospectus,  and A-Fem failed to
deliver  a  copy  of  the  final  or  amended  prospectus  at or  prior  to  the
confirmation  of the sale of the  securities  to the person  asserting  any such
loss, claim, damage or liability in any case where such delivery is

                                       8

<PAGE>



required  by the 1933  Act;  and  provided,  further,  that the  indemnification
obligation of Holder shall be limited to the aggregate  public offering price of
the Registrable Securities sold by Holder pursuant to such registration.

         6.3   Notice, Defense and Counsel

         Promptly after receipt by an indemnified  party under this Section 6 of
notice of the commencement of any action  (including any  governmental  action),
such indemnified party will, if a claim in respect thereof is to be made against
any indemnifying party under this Section 6, deliver to the indemnifying party a
written notice of the commencement thereof and the indemnifying party shall have
the right to  participate  in,  and,  to the  extent the  indemnifying  party so
desires,  jointly with any other indemnifying party similarly noticed, to assume
and  control the defense  thereof  with  counsel  mutually  satisfactory  to the
parties;  provided,  however,  that an indemnified party shall have the right to
retain  its  own  counsel,  with  the  fees  and  expenses  to be  paid  by  the
indemnifying  party, if  representation of such indemnified party by the counsel
retained  by the  indemnifying  party  would be  inappropriate  due to actual or
potential differing interests between such indemnified party and any other party
represented by such counsel in such  proceeding.  The failure to deliver written
notice to the indemnifying party within a reasonable time of the commencement of
any such action,  if  materially  and  adversely  prejudicial  to its ability to
defend such action,  shall relieve such  indemnifying  party of any liability to
the indemnified party under this Section 6 to the extent of such prejudice,  but
the omission so to deliver  written  notice to the  indemnifying  party will not
relieve it of any liability that it may have to any indemnified  party otherwise
than under this Section 6.

         6.4   Contribution

         If the  indemnification  provided  for in this  Section  6 is held by a
court of competent  jurisdiction to be unavailable to an indemnified  party with
respect to any losses,  claims,  damages or liabilities  referred to herein, the
indemnifying  party, in lieu of indemnifying  such indemnified party thereunder,
shall, to the extent permitted by applicable law,  contribute to the amount paid
or payable by such indemnified party as a result of such loss, claim,  damage or
liability in such  proportion as is appropriate to reflect the relative fault of
the  indemnifying  party, on the one hand, and of the indemnified  party, on the
other, in connection with the  Violation(s)  that resulted in such loss,  claim,
damage or liability, as well as any other relevant equitable considerations. The
relative fault of the indemnifying  party and of the indemnified  party shall be
determined by a court of law by reference  to, among other  things,  whether the
untrue or allegedly untrue statement of a material fact or the omission to state
a material fact relates to information supplied by the indemnifying party or by


                                       9

<PAGE>

the indemnified  party and the parties'  relative intent,  knowledge,  access to
information and opportunity to correct or prevent such statement or omission.

         6.5   Survival of Rights and Obligations

         The  obligations of A-Fem and Holder under this Section 6 shall survive
the  completion  of any offering of  Registrable  Securities  in a  registration
statement whether under this Agreement or otherwise.

         7.    Reports Under the 1934 Act

         With a view  to  making  available  to  Holder  benefits  of  Rule  144
promulgated  under the 1933 Act and any other rule or regulation of the SEC that
may at any time permit Holder to sell  securities of A-Fem to the public without
registration, A-Fem agrees to use its best efforts to:

         (a)  make and keep public information available, as those terms are
understood and defined in Rule 144, at all times;

         (b)  file  with  the SEC in a  timely  manner  all  reports  and  other
documents required of A-Fem under the 1933 Act and the 1934 Act; and

         (c)  furnish  to  Holder,  so  long  as  Holder  owns  any  Registrable
Securities,  forthwith upon request (i) a written statement by A-Fem that it has
complied with the reporting  requirements of Rule 144, the 1933 Act and the 1934
Act  (at any and  all  times  after  it has  become  subject  to such  reporting
requirements),  or that it  qualifies as a registrant  whose  securities  may be
resold  pursuant to Form S-2 or S-3 (at any time after it so qualifies),  (ii) a
copy of the most  recent  annual or  quarterly  report  of A-Fem and such  other
reports and documents so filed by A-Fem, and (iii) such other information as may
be reasonably  requested in availing Holder of any rule or regulation of the SEC
that permits the selling of any such securities without registration or pursuant
to such form.

         8.    Lock-Up Agreement

         Holder, if requested by A-Fem and an underwriter of A-Fem's  securities
(in a firmly underwritten public offering), shall agree not to sell or otherwise
transfer or dispose of any Registrable  Securities or other  securities of A-Fem
held by Holder for a specified  period of time (not to exceed 90 days) following
the effective date of a registration  statement pursuant to which A-Fem proposes
to sell its securities to the public generally,  provided, however, that holders
of at least five percent of A-Fem's  Common Stock and all officers and directors
of A-Fem enter into similar agreements.

                                       10

<PAGE>

         9.    Assignment of Registration Rights

         The right to cause  A-Fem to  register  Common  Stock  pursuant to this
Agreement may not be assigned or transferred  without the prior written  consent
of A-Fem, which consent will not be unreasonably withheld.

         10.   Amendment

         Any  provision  of this  Agreement  may be amended  and the  observance
thereof may be waived (either  generally or in a particular  instance and either
retroactively or prospectively),  only with the written consent of A-Fem and the
Holders of a majority of the  Registrable  Securities.  Any  amendment or waiver
effected in  accordance  with this Section shall be binding upon each Holder and
A-Fem.

         11.   Termination of Registration Rights

         No Holder shall be entitled to exercise any right  provided for in this
Agreement after five (5) years following the date hereof.

         12.   Attorneys' Fees

         In the event any legal  action is brought  by any party to enforce  the
terms of this  Agreement,  the  prevailing  party  shall be  entitled to recover
reasonable  attorneys'  fees and expenses in addition to any other relief deemed
appropriate by the trial court or any appellate court or any bankruptcy court.

         13.   Successors

         Subject to Section 9 hereof, this Agreement shall bind and inure to the
benefit of the successors and assigns of A-Fem and the Holders.

         14.   Entire Agreement

         This Agreement  constitutes the entire agreement among the parties with
respect to the subject matter hereof and supersedes  all prior  arrangements  or
understandings.

         15.   Notices

         All notices,  requests,  consents and other communications  required or
provided for herein to any party shall be deemed to be  sufficient  if contained
in a written instrument,  and shall be deemed to be given when: (a) delivered in
person;  (b) sent by  first-class  registered  or  certified  mail with  postage
prepaid;  (c) delivered by overnight  receipted courier service;  or (d) sent by
facsimile transmission with delivery

                                       11

<PAGE>

confirmed and followed by delivery pursuant to (b) hereof, which notice is
addressed to the party at the address set forth below,  or such other address
as may hereafter be designated in writing by the party.

         If to A-Fem:               10180 S.W. Nimbus Avenue, Suite J-5
                                    Portland, OR  97223
                                    Attention:  Steven T. Frankel, President
                                       and Chief Executive Officer
                                    Telephone:  (503) 968-8800
                                    Facsimile:  (503) 639-3674

         with a copy to:            Patrick J. Simpson
                                    Perkins Coie, LLP
                                    1211 SW Fifth Avenue, Suite 1500
                                    Portland, OR  97204-3715
                                    Telephone:  (503) 727-2000
                                    Facsimile:  (503) 727-2222

         If to the Holder:          Capital Consultants LLC
                                    2300 SW First Avenue, Suite 200
                                    Portland, OR  97201
                                    Attention:  Jeffrey L. Grayson
                                    Telephone:  (503) 241-1200
                                    Facsimile:  (503) 241-0207

         with a copy to:            Carmen M. Calzacorta
                                    Schwabe, Williamson & Wyatt
                                    1211 SW Fifth Avenue, Suite 1600-1800
                                    Portland, OR  97204
                                    Telephone:  (503) 796-2994
                                    Facsimile:  (503) 796-2900

         16.   Event of Default

         An Event of Default shall have occurred  under this  Agreement if A-Fem
shall fail to perform any  obligation  under this  Agreement  within thirty (30)
days after  notice  from any  Holder  specifying  the  nature of the  failure of
default.

                                       12

<PAGE>


         17.   Counterparts

         This Agreement may be executed in any number of counterparts,  and each
such  counterpart  shall  be  deemed  to be an  original  instrument.  All  such
counterparts together shall constitute one agreement.

         18.   Headings

         The  headings  of the  various  sections  of this  Agreement  have been
inserted for  convenience of reference only and shall not be deemed to be a part
of this Agreement.

         19.   Governing Law

         This  Agreement  shall be governed by and construed in accordance  with
the laws of the State of Oregon.

         [this space intentionally left blank]


                                       13

<PAGE>

         IN WITNESS  WHEREOF,  the parties  hereto have executed or caused their
duly  authorized  representative  to execute this Agreement as of the date first
herein above written.



                                     Holder by:

                                     CAPITAL CONSULTANTS LLC, as agent

                                     /s/ Barclay Grayson
                                     -------------------------------------
                                     By: Barclay Grayson

                                     Its  President


                                     A-FEM:

                                     A-FEM MEDICAL CORPORATION

                                     /s/ Steven T. Frankel
                                     -------------------------------------
                                     By:  Steven T. Frankel
                                     Its:  Chief Executive Officer and President


                                       14



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