DREYFUS NEW LEADERS FUND INC
N-30D/A, 2000-02-29
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Dreyfus New Leaders

Fund, Inc.

ANNUAL REPORT December 31, 1999

(reg.tm)





The  views  expressed herein are current to the date of this report. These views
and  the  composition  of the fund's portfolio are subject to change at any time
based on market and other conditions.

   * Not FDIC-Insured
   * Not Bank-Guaranteed
   * May Lose Value

Year 2000 Issues (Unaudited)

The fund could be adversely affected if the computer systems used by Dreyfus and
the fund's other service providers do not properly process and calculate
date-related information from and after January 1, 2000. Dreyfus has taken steps
designed to avoid year 2000-related problems in its systems and to monitor the
readiness  of other service providers.  In addition, issuers of securities in
which the fund invests may be adversely affected by year 2000-related problems.
This could have an impact on the value of the fund's investments and its share
price.


                                 Contents

                                 THE FUND
- --------------------------------------------------

                             2   Letter from the President

                             3   Discussion of Fund Performance

                             6   Fund Performance

                             7   Statement of Investments

                            10   Statement of Assets and Liabilities

                            11   Statement of Operations

                            12   Statement of Changes in Net Assets

                            13   Financial Highlights

                            14   Notes to Financial Statements

                            19   Report of Independent Auditors

                            20   Important Tax Information

                                 FOR MORE INFORMATION
- ---------------------------------------------------------------------------

                                 Back Cover

                                                                        The Fund

                                                  Dreyfus New Leaders Fund, Inc.

LETTER FROM THE PRESIDENT

Dear Shareholder:

We are pleased to present this annual report for Dreyfus New Leaders Fund, Inc.,
covering  the  12-month  period  from January 1, 1999 through December 31, 1999.
Inside,  you' ll  find  valuable  information  about  how  the fund was managed,
including a discussion with the fund's portfolio managers, Hilary Woods and Paul
Kandel.

The  past year has been both highly volatile and rewarding for investors in U.S.
stocks,  including  the mid-capitalization sector of the market. On December 31,
the  last  trading  day  of 1999, most major stock market indices hit new highs,
including  the  Dow  Jones  Industrial  Average,  the S&P 500 Index of large-cap
stocks,   the  technology-heavy  Nasdaq  100  and  the  Russell  2000  Index  of
small-capitalization stocks.

These  simultaneous highs masked the remarkable narrowness of the stock market's
advance  in  1999,  however.  Growth-oriented midcap stocks handily outperformed
value-oriented  midcap  stocks.  Indeed,  the  market' s stellar performance was
generally   limited   to   a   handful   of   highly   valued   technology   and
telecommunications  companies,  some of which had no earnings. In our view, many
fundamentally  sound midcap companies in other market sectors may now be selling
at attractive valuations.

We  appreciate  your  confidence over the past year, and we look forward to your
continued    participation    in    Dreyfus    New    Leaders    Fund,    Inc.

Sincerely,


Stephen E. Canter

President and Chief Investment Officer

The Dreyfus Corporation

January 14, 2000




DISCUSSION OF FUND PERFORMANCE

Hilary Woods and Paul Kandel, Portfolio Managers

How did Dreyfus New Leaders Fund, Inc. perform  relative to its benchmark?

For  the 12-month period ended December 31, 1999, Dreyfus New Leaders Fund, Inc.
produced  a  total return of 37.42%.(1) The fund's 12-month performance exceeded
the  Russell  2500  Index,  which produced a total return of 24.15% for the same
period.(2)

We  attribute  the  fund' s performance to our success in identifying attractive
individual investment opportunities among a diverse range of sectors, industries
and  investment  styles.  In addition, the fund succeeded in emphasizing some of
the market's strongest sectors.

What is the fund's investment approach?

The  fund  invests  primarily  in  a  diversified portfolio of midcap companies,
focusing on new leaders in their industries that offer products or services that
we  believe  enhance  prospects  for  growth  of  future  earnings. We also base
investment  decisions  on  economic  or political conditions that we believe are
likely  to  affect  a  stock' s  performance,  and on the impact of changes in a
company's management or organizational structure.

Our  investment approach targets both growth-oriented stocks (those of companies
with  earnings  that  are  expected to grow faster than the overall market), and
value-oriented  stocks  (those that appear underpriced according to a variety of
financial  measurements) . We  further  diversify  among  the  market' s various
industries  and sectors, supervising a team of sector managers who each make buy
and sell decisions within their respective areas of expertise.

What other factors influenced the fund's performance?

The  fund  achieved  high returns overall, particularly in the consumer products
sector, because of high levels of consumer confidence throughout the period. Our
best    performers    included    Hispanic     The    Fund


DISCUSSION OF FUND PERFORMANCE (CONTINUED)

Broadcasting,  which  benefited  from  the  growth  of targeted marketing to the
fast-growing  Spanish community in the United States; Gemstar International, the
maker  of  VCR  Plus and satellite TV programming guides; and Tiffany & Co., the
luxury retailer.

The  fund  was  also  affected  by  the U.S. economy, which exhibited consistent
strength throughout the period. Most global economies showed signs of a cyclical
resurgence  as well. Increasing global economic activity led to a growing demand
for energy, communications and basic industrial resources. Many of the companies
in which the fund invested benefited as a result.

Rising energy prices fueled advances in our holdings of oil drilling and service
companies,   such   as  Noble  Drilling  and  Weatherford  International.  Among
utilities,   we  connected  with  telecommunications-related  stocks,  including
Metromedia  Fiber  Network,  Cl.  A.,  which  provides  telephone  companies and
corporations   with   the   increased   bandwidth  required  for  data-intensive
communications.  In  the  materials  and  processing  sector,  we produced solid
returns   with  investments  in  companies  benefiting  from  increasing  global
industrial  activity.  Our  strongest  performers  in the sector included metals
mining  and development companies, such as Freeport-McMoRan Copper, and Bowater,
a  leading  producer  of  newsprint.  Other  profitable  sectors  for investment
included transportation and technology.

Of  course  not  every  company in the fund's portfolio showed positive returns.
Some  stocks  lagged,  even  among  our  best-performing  sectors. The fund also
experienced   weak  performance  throughout  the  period  from  two  sectors  in
particular:  health  care and finance. The health care sector was battered by an
increasingly  restrictive  regulatory  environment  and the prospect for further
government-imposed limitations on Medicare and Medicaid reimbursements. The fund
benefited  from  holdings  of  stocks such as Allergan, a growing pharmaceutical
company,  and  Centocor, an advanced-stage biotech company. However, those gains
were  more  than  matched  by  losses  in  health  services  companies  such  as
Healthsouth,  a provider of outpatient surgery and rehabilitation, which we sold
during the reporting period.


Financial  stocks generally suffered in 1999's rising interest-rate environment.
As a result, many of the fund's financial company holdings failed to show strong
gains,   and   some,   such   as   Enhance  Financial  and  Berkley  Insurance,
underperformed.  Both  of  these holdings were sold during the reporting period.
Exceptions included UnionBanCal, which benefited from effective cost cutting and
accelerating  local growth, and market maker Knight/Trimark Group, which rose on
news of its market share gains.

What is the fund's current strategy?

As  of  the end of the reporting period, the fund remained more heavily weighted
than its benchmark in the sectors that provided the strongest performance during
1999,  including technology, consumer products, energy, utilities, and materials
and   processing.   We   remained   underweighted  in  last  year' s  relatively
weak-performing  sectors of health care and financial services. Of course, there
is no guarantee how these sectors will perform in 2000.

We  continue  to believe that midcap stocks of fast-growing new leaders in their
industries  offer  the  potential  for  strong  growth and above-average capital
appreciation.  Accordingly,  we  have  continued  to  target  such  stocks while
adhering  to  our  blended  growth-and-value  investment  strategy in seeking to
outperform the Russell 2500 Index.

We  remain  sanguine  on  technology and energy given the strong earnings growth
prospects  for  these  two  groups  and  their historically strong first quarter
performance. We are sticking with our caution on financial services near term in
view of likely continued unfriendly Fed policy.

January 14, 2000

(1)   TOTAL RETURN INCLUDES REINVESTMENT OF DIVIDENDS AND ANY CAPITAL GAINS
PAID. PAST PERFORMANCE IS NO GUARANTEE OF FUTURE RESULTS. SHARE PRICE AND
INVESTMENT RETURN FLUCTUATE SUCH THAT UPON REDEMPTION, FUND SHARES MAY BE WORTH
MORE OR LESS THAN THEIR ORIGINAL COST.

(2)  SOURCE: FACTSET RESEARCH SYSTEMS, INC. -- REFLECTS THE REINVESTMENT OF
INCOME DIVIDENDS AND, WHERE APPLICABLE, CAPITAL GAIN DISTRIBUTIONS. THE RUSSELL
2500 INDEX IS A WIDELY ACCEPTED, UNMANAGED INDEX OF SMALL- TO MID-CAP STOCK
PERFORMANCE AND IS COMPOSED OF THE 2,500 SMALLEST COMPANIES IN THE RUSSELL 3000
INDEX. THE RUSSELL 3000 INDEX IS COMPOSED OF THE LARGEST U.S. COMPANIES BY
MARKET CAPITALIZATION.

                                                                        The Fund
<TABLE>
<CAPTION>

FUND PERFORMANCE

Comparison of change in value of $10,000 investment in Dreyfus New Leaders Fund,
Inc. and the Russell 2500 Index
- --------------------------------------------------------------------------------

Average Annual Total Returns AS OF 12/31/99

                                           Inception                                                                 From
                                             Date            1 Year            5 Years           10 Years          Inception
- ------------------------------------------------------------------------------------------------------------------------------------

<S>                                         <C>               <C>               <C>                <C>               <C>
FUND                                        1/29/85          37.42%            19.16%             14.69%            15.98%

(+)  SOURCE: FACTSET RESEARCH SYSTEMS, INC.
</TABLE>

PAST PERFORMANCE IS NOT PREDICTIVE OF FUTURE PERFORMANCE.

THE ABOVE GRAPH COMPARES A $10,000 INVESTMENT MADE IN DREYFUS NEW LEADERS FUND,
INC. ON 1/29/85 (INCEPTION DATE) TO A $10,000 INVESTMENT MADE IN THE RUSSELL
2500 INDEX ON THAT DATE.  FOR COMPARATIVE PURPOSES, THE VALUE OF THE INDEX ON
1/31/85 IS USED AS THE BEGINNING VALUE ON 1/29/85. ALL DIVIDENDS AND CAPITAL
GAIN DISTRIBUTIONS ARE REINVESTED.

THE FUND'S PERFORMANCE  SHOWN IN THE LINE GRAPH TAKES INTO ACCOUNT ALL
APPLICABLE FEES AND EXPENSES.  THE RUSSELL 2500 INDEX IS AN UNMANAGED INDEX AND
IS COMPOSED OF THE 2,500 SMALLEST COMPANIES IN THE RUSSELL 3000 INDEX. THE
RUSSELL 3000 INDEX IS COMPOSED OF 3,000 OF THE LARGEST U.S. COMPANIES BY MARKET
CAPITALIZATION.  THE INDEX DOES NOT TAKE INTO ACCOUNT CHARGES, FEES AND OTHER
EXPENSES.  FURTHER INFORMATION RELATING TO FUND PERFORMANCE, INCLUDING EXPENSE
REIMBURSEMENTS, IF APPLICABLE, IS CONTAINED IN THE FINANCIAL HIGHLIGHTS SECTION
OF THE PROSPECTUS AND ELSEWHERE IN THIS REPORT.


<TABLE>
<CAPTION>



STATEMENT OF INVESTMENTS

December 31, 1999

COMMON STOCKS--97.2%                                                                                  Shares           Value ($)
- ------------------------------------------------------------------------------------------------------------------------------------

AUTO RELATED--3.0%

<S>                                                                                             <C>                   <C>
Expeditors International of Washington                                                          250,000               10,953,125

Navistar International                                                                          200,000  (a)           9,475,000

                                                                                                                      20,428,125

CONSUMER--21.0%

AMFM                                                                                            170,000  (a)          13,302,500

Gemstar International                                                                           340,000  (a)          24,225,000

Hispanic Broadcasting                                                                           210,000  (a)          19,365,938

Infinity Broadcasting, Cl. A                                                                    487,500  (a)          17,641,406

Mandalay Resort Group                                                                           425,000  (a)           8,553,125

Meredith                                                                                        250,000               10,421,875

Ticketmaster Online-CitySearch, Cl. B                                                           250,000  (a)           9,609,375

Tiffany & Co.                                                                                   270,000               24,097,500

USA Networks                                                                                    255,000  (a)          14,088,750

                                                                                                                     141,305,469

ELECTRONIC TECHNOLOGY--11.9%

ASM Lithography Holding                                                                         165,000  (a)          18,768,750

Altera                                                                                          230,000  (a)          11,399,375

National Semiconductor                                                                          375,000  (a)          16,054,688

Teradyne                                                                                        280,000  (a)          18,480,000

Vitesse Semiconductor                                                                           290,000  (a)          15,206,875

                                                                                                                      79,909,688

ENERGY--8.1%

Apache                                                                                          165,000                6,094,687

ENSCO International                                                                             375,000                8,578,125

Noble Drilling                                                                                  475,000  (a)          15,556,250

USX-U.S. Steel Group                                                                            335,000               11,055,000

Weatherford International                                                                       335,000  (a)          13,379,062

                                                                                                                      54,663,124

FINANCE--11.3%

Charter One Financial                                                                           325,237                6,220,158

Compass Bancshares                                                                              300,000                6,693,750

Dime Bancorp                                                                                    200,000                3,025,000

First Tennessee National                                                                        275,000                7,837,500

First Virginia Banks                                                                            195,000                8,385,000

Knight/Trimark Group, Cl. A                                                                     200,000  (a)           9,200,000

Protective Life                                                                                 265,000                8,430,312

T. Rowe Price Associates                                                                        225,000                8,310,938

                                                                                                     The Fund


STATEMENT OF INVESTMENTS (CONTINUED)

COMMON STOCKS (CONTINUED)                                                                        Shares                Value ($)
- ------------------------------------------------------------------------------------------------------------------------------------

FINANCE (CONTINUED)

UnionBanCal                                                                                     240,000                9,465,000

XL Capital, Cl. A                                                                               170,000                8,818,750

                                                                                                                      76,386,408

FOREST & PAPER PRODUCTS--1.4%

Consolidated Papers                                                                             300,000                9,543,750

HEALTH CARE--7.3%

Allergan                                                                                        220,000               10,945,000

Bard (C.R.)                                                                                     170,000                9,010,000

Sepracor                                                                                         85,000  (a)           8,430,938

Teva Pharmaceutical Industries, ADR                                                             165,000               11,828,437

Watson Pharmaceuticals                                                                          240,000  (a)           8,595,000

                                                                                                                      48,809,375

MATERIALS & PROCESSING--8.2%

Bowater                                                                                         150,000                8,146,875

Eastman Chemical                                                                                175,000                8,345,312

Engelhard                                                                                       500,000                9,437,500

Fluor                                                                                           200,000                9,175,000

Freeport-McMoRan Copper, Cl. B                                                                  550,000  (a)          11,618,750

International Flavors & Fragrances                                                              225,000                8,493,750

                                                                                                                      55,217,187

PRODUCER DURABLES--3.9%

CNH Global                                                                                       60,900                  810,731

Cordant Technologies                                                                            200,000                6,600,000

Grainger (W.W.)                                                                                 175,000                8,367,188

Howmet International                                                                            125,000  (a)           2,257,812

Northrop Grumman                                                                                150,000                8,109,375

                                                                                                                      26,145,106

TECHNOLOGY--14.4%

Adaptec                                                                                         275,000  (a)          13,715,625

Ciena                                                                                           250,000  (a)          14,375,000

Citrix Systems                                                                                  135,000  (a)          16,605,000

Flextronics International                                                                       240,000  (a)          11,040,000

Intuit                                                                                          300,000  (a)          17,981,250

Lexmark International Group, Cl. A                                                              115,000  (a)          10,407,500

Scientific-Atlanta                                                                              225,000               12,515,625

                                                                                                                      96,640,000


STATEMENT OF INVESTMENTS (CONTINUED)

COMMON STOCKS (CONTINUED)                                                                        Shares                Value ($)
- ------------------------------------------------------------------------------------------------------------------------------------

UTILITIES & OTHER--6.7%

Illinova                                                                                        280,000                9,730,000

ITC DeltaCom                                                                                    520,000  (a)          14,365,000

Metromedia Fiber Network, Cl. A                                                                 350,000  (a)          16,778,125

Nicor                                                                                           120,000                3,900,000

Separation Technologies                                                                          81,984  (a,b,c)         311,539

                                                                                                                      45,084,664

TOTAL COMMON STOCKS

   (cost $372,438,826)                                                                                               654,132,896
- ------------------------------------------------------------------------------------------------------------------------------------

PREFERRED STOCKS--.1%
- ------------------------------------------------------------------------------------------------------------------------------------

Separation Technologies,

  Ser. A, 6%, Cum. Conv.

   (cost $931,463)                                                                              243,385  (a,b,c)         924,863
- ------------------------------------------------------------------------------------------------------------------------------------

                                                                                              Principal

SHORT-TERM INVESTMENTS--3.6%                                                                 Amount ($)                Value ($)
- ------------------------------------------------------------------------------------------------------------------------------------

U.S. TREASURY BILLS:

   5.18%, 1/13/2000                                                                          10,277,000               10,263,743

   5.05%, 1/20/2000                                                                           4,117,000                4,107,984

   5%, 2/3/2000                                                                               6,729,000                6,702,218

   5.05%, 3/16/2000                                                                             269,000                  266,232

   5.07%, 3/30/2000                                                                           3,247,000                3,206,510

TOTAL SHORT-TERM INVESTMENTS

   (cost $24,535,857)                                                                                                 24,546,687

TOTAL INVESTMENTS (cost $397,906,146)                                                            100.9%              679,604,446

LIABILITIES, LESS CASH AND RECEIVABLES                                                             (.9%)              (6,253,643)

NET ASSETS                                                                                       100.0%              673,350,803

(A) NON-INCOME PRODUCING.

(B) INVESTMENTS IN NON-CONTROLLED AFFILIATES (COST $1,243,000)--SEE NOTE 1(D).

(C)  SECURITIES RESTRICTED AS TO PUBLIC RESALE. INVESTMENTS IN RESTRICTED
SECURITIES, WITH AN AGGREGATE VALUE OF $1,236,402 REPRESENTS APPROXIMATELY .18%
OF NET ASSETS:
</TABLE>
<TABLE>
<CAPTION>

                                                      Acquisition           Purchase
Issuer                                                       Date          Price ($)              Net Assets (%)  Valuation ($)(+)
- ------------------------------------------------------------------------------------------------------------------------------------

<S>                                                       <C>                   <C>                     <C>          <C>
Separation Technologies                                   1/13/95               3.80                    .04          3.80

Separation Technologies,
   Ser. A, 6%, Cum. Conv.                         7/12/93-1/13/95               3.80                    .14          3.80

(+)  THE VALUATION OF THESE SECURITIES HAS BEEN DETERMINED IN GOOD FAITH UNDER
     THE DIRECTION OF THE BOARD OF DIRECTORS.

SEE NOTES TO FINANCIAL STATEMENTS.
</TABLE>

                                                                        The Fund


STATEMENT OF ASSETS AND LIABILITIES

December 31, 1999

                                                             Cost         Value
- --------------------------------------------------------------------------------

ASSETS ($):

Investments in securities--See Statement of
Investments                                           397,906,146   679,604,446

Cash                                                                     32,514

Dividends receivable                                                    594,349

Receivable for shares of Common Stock subscribed                        133,645

Prepaid expenses                                                         27,530

                                                                    680,392,484
- --------------------------------------------------------------------------------

LIABILITIES ($):

Due to The Dreyfus Corporation and affiliates                           595,363

Payable for shares of Common Stock redeemed                           5,581,422

Payable for investment securities purchased                             781,025

Accrued expenses                                                         83,871

                                                                      7,041,681
- --------------------------------------------------------------------------------

NET ASSETS ($)                                                      673,350,803
- --------------------------------------------------------------------------------

COMPOSITION OF NET ASSETS ($):

Paid-in capital                                                     358,995,740

Accumulated net realized gain (loss) on investments                  32,656,763

Accumulated net unrealized appreciation (depreciation)

   on investments--Note 4                                           281,698,300
- --------------------------------------------------------------------------------

NET ASSETS ($)                                                      673,350,803
- --------------------------------------------------------------------------------

SHARES OUTSTANDING

(100 million shares of $.01 par value Common Stock authorized)       13,287,897

NET ASSET VALUE, offering and redemption price per share--Note 3(d) ($)
                                                                          50.67

SEE NOTES TO FINANCIAL STATEMENTS.




STATEMENT OF OPERATIONS

Year Ended December 31, 1999

- --------------------------------------------------------------------------------

INVESTMENT INCOME ($):

INCOME:

Cash dividends (net of $13,009 foreign taxes withheld at source)     5,122,333

Interest                                                             1,366,017

TOTAL INCOME                                                         6,488,350

EXPENSES:

Management fee--Note 3(a)                                            4,658,175

Shareholder servicing costs--Note 3(b)                               2,067,950

Custodian fees--Note 3(b)                                               58,362

Prospectus and shareholders' reports                                    57,404

Professional fees                                                       49,870

Registration fees                                                       49,034

Directors' fees and expenses--Note 3(c)                                 42,885

Loan commitment fees--Note 2                                             5,531

Miscellaneous                                                           10,845

TOTAL EXPENSES                                                       7,000,056

INVESTMENT (LOSS)                                                     (511,706)
- --------------------------------------------------------------------------------

REALIZED AND UNREALIZED GAIN (LOSS) ON INVESTMENTS--NOTE 4 ($):

Net realized gain (loss) on investments                            105,055,980

Net unrealized appreciation (depreciation) on investments           94,099,759

NET REALIZED AND UNREALIZED GAIN (LOSS) ON INVESTMENTS             199,155,739

NET INCREASE IN NET ASSETS RESULTING FROM OPERATIONS               198,644,033

SEE NOTES TO FINANCIAL STATEMENTS.

                                                                        The Fund


STATEMENT OF CHANGES IN NET ASSETS

                                                     Year Ended December 31,
                                              ----------------------------------

                                                     1999                 1998
- --------------------------------------------------------------------------------

OPERATIONS ($):

Investment (loss)                                (511,706)           (1,678,401)

Net realized gain (loss) on investments       105,055,980               (83,704)

Net unrealized appreciation (depreciation)
   on investments                              94,099,759           (27,003,995)

NET INCREASE (DECREASE) IN NET ASSETS
   RESULTING FROM OPERATIONS                  198,644,033           (28,766,100)
- --------------------------------------------------------------------------------

DIVIDENDS TO SHAREHOLDERS FROM ($):

NET REALIZED GAIN ON INVESTMENTS              (71,263,590)          (20,245,621)
- --------------------------------------------------------------------------------

CAPITAL STOCK TRANSACTIONS ($):

Net proceeds from shares sold                 187,240,492           327,144,836

Dividends reinvested                           68,092,489            19,379,693

Cost of shares redeemed                      (394,139,085)         (472,441,525)

Redemption fee                                     28,029               143,546

INCREASE (DECREASE) IN NET ASSETS
   FROM CAPITAL STOCK TRANSACTIONS           (138,778,075)         (125,773,450)

TOTAL INCREASE (DECREASE) IN NET ASSETS       (11,397,632)         (174,785,171)
- --------------------------------------------------------------------------------

NET ASSETS ($):

Beginning of Period                           684,748,435          859,533,606

END OF PERIOD                                 673,350,803          684,748,435
- --------------------------------------------------------------------------------

CAPITAL SHARE TRANSACTIONS (SHARES):

Shares sold                                     4,044,076            7,407,474

Shares issued for dividends reinvested          1,379,412              517,921

Shares redeemed                                (8,710,510)         (10,732,055)

NET INCREASE (DECREASE) IN SHARES OUTSTANDING  (3,287,022)          (2,806,660)

SEE NOTES TO FINANCIAL STATEMENTS.


<TABLE>
<CAPTION>

FINANCIAL HIGHLIGHTS

The  following table describes the performance for the fiscal periods indicated.
Total return shows how much your investment in the fund would have increased (or
decreased)  during  each  period,  assuming you had reinvested all dividends and
distributions.  These  figures  have  been  derived  from  the  fund's financial
statements.

                                                                                Year Ended December 31,
                                                                      --------------------------------------------

                                                                 1999        1998        1997        1996        1995
- ------------------------------------------------------------------------------------------------------------------------------------

PER SHARE DATA ($):

<S>                                                             <C>         <C>          <C>        <C>         <C>
Net asset value, beginning of period                            41.31       44.35        40.74      37.39       31.33

Investment Operations:

Investment income (loss)--net                                    (.04)(a)    (.10)        (.14)      (.05)        .06

Net realized and unrealized

   gain (loss) on investments                                   15.33       (1.78)        7.99       6.47        9.17

Total from Investment Operations                                15.29       (1.88)        7.85       6.42        9.23

Distributions:

Dividends from investment income--net                              --          --          --          --        (.07)

Dividends from net realized gain
   on investments                                               (5.93)      (1.17)      (4.24)      (3.07)      (3.10)

Total Distributions                                             (5.93)      (1.17)      (4.24)      (3.07)      (3.17)

Redemption fee added to paid-in capital                           .00(b)      .01          --          --          --

Net asset value, end of period                                  50.67       41.31       44.35       40.74       37.39
- ------------------------------------------------------------------------------------------------------------------------------------

TOTAL RETURN (%)                                                37.42       (3.95)      19.54       17.31       29.80
- ------------------------------------------------------------------------------------------------------------------------------------

RATIOS/SUPPLEMENTAL DATA (%):

Ratio of expenses to average net assets                          1.13        1.14        1.12        1.17        1.19

Ratio of net investment income (loss)

   to average net assets                                         (.08)       (.21)       (.33)       (.15)        .17

Decrease reflected in above expense ratios

   due to undertakings by
   The Dreyfus Corporation                                         --          --          --          --         .02

Portfolio Turnover Rate                                         95.49      107.38       82.28      102.22      108.80
- ------------------------------------------------------------------------------------------------------------------------------------

Net Assets, end of period ($ x 1,000)                         673,351     684,748     859,534     780,999     606,945

(A) BASED ON AVERAGE SHARES OUTSTANDING AT EACH MONTH END.

(B) AMOUNT REPRESENTS LESS THAN $.01.
</TABLE>

SEE NOTES TO FINANCIAL STATEMENTS.

                                                             The Fund



NOTES TO FINANCIAL STATEMENTS

NOTE 1--Significant Accounting Policies:

Dreyfus  New  Leaders Fund, Inc. (the "fund") is registered under the Investment
Company  Act  of  1940,  as  amended  (the  "Act" ), as  a  diversified open-end
management  investment  company.  The fund's investment objective is to maximize
capital  appreciation.  The  Dreyfus  Corporation  (the "Manager") serves as the
fund' s  investment  adviser. The Manager is a direct subsidiary of Mellon Bank,
N.A.  (" Mellon" ), which  is  a  wholly-owned  subsidiary  of  Mellon Financial
Corporation.  Premier  Mutual  Fund  Services,  Inc.  (the "Distributor") is the
distributor  of  the fund's shares, which are sold to the public without a sales
charge.

The  fund' s  financial  statements  are  prepared  in accordance with generally
accepted accounting principles which may require the use of management estimates
and assumptions. Actual results could differ from those estimates.

(a)  Portfolio valuation: Investments in securities are valued at the last sales
price  on  the securities exchange on which such securities are primarily traded
or  at  the  last  sales price on the national securities market. Securities not
listed on an exchange or the national securities market, or securities for which
there were no transactions, are valued at the average of the most recent bid and
asked prices, except for open short positions, where the asked price is used for
valuation  purposes.  Bid  price  is  used  when  no  asked  price is available.
Securities  for  which  there are no such valuations are valued at fair value as
determined  in  good  faith  under  the  direction  of  the  Board of Directors.
Investments  denominated in foreign currencies are translated to U.S. dollars at
the    prevailing    rates    of    exchange.

(b) Foreign currency transactions: The fund does not isolate that portion of the
results  of  operations  resulting  from  changes  in  foreign exchange rates on
investments  from  the fluctuations arising from changes in the market prices of
securities  held.  Such  fluctuations  are  included  with  the net realized and
unrealized gain or loss from investments.

Net realized foreign exchange gains or losses arise from sales and maturities of
short-term securities, sales of foreign currencies, cur

rency  gains  or  losses  realized on securities transactions and the difference
between the amount of dividends, interest and foreign withholding taxes recorded
on  the  fund' s  books  and  the U.S. dollar equivalent of the amounts actually
received  or  paid.  Net unrealized foreign exchange gains and losses arise from
changes  in  the  value  of  assets  and  liabilities  other than investments in
securities,  resulting from changes in exchange rates. Such gains and losses are
included with net realized and unrealized gain or loss on investments.

(c)  Securities  transactions and investment income: Securities transactions are
recorded  on  a  trade  date  basis.  Realized  gain  and  loss  from securities
transactions  are  recorded  on  the  identified  cost basis. Dividend income is
recognized  on  the  ex-dividend  date  and  interest  income,  including, where
applicable,  amortization  of  discount  on  investments,  is  recognized on the
accrual  basis.  Under the terms of the custody agreement, the fund received net
earnings  credits  of  $8,785 during the period ended December 31, 1999 based on
available cash balances left on deposit. Income earned under this arrangement is
included in interest income.

(d)  Affiliated  issuers:  Issuers  in  which  the  fund  held 5% or more of the
outstanding  voting  securities  are  defined  as  "affiliated"  in the Act. The
following  summarizes  non-controlled affiliated issuers during the period ended
December 31, 1999:
<TABLE>
<CAPTION>

                                                          Shares
                                       ----------------------------------------------

                                    Beginning                                End of      Dividend            Market
Name of issuer                      of Period        Purchases      Sales    Period      Income ($)          Value ($)
- ------------------------------------------------------------------------------------------------------------------------------------

Separation
<S>                                    <C>                                  <C>                             <C>
Technologies                           81,984             --         --     81,984            --            311,539

(Common)

Separation
Technologies                          243,385             --         --    243,385            --            924,863
(Conv. Preferred)
</TABLE>

(e)  Dividends  to shareholders: Dividends are recorded on the ex-dividend date.
Dividends  from  investment  income-net  and dividends from net realized capital
gain   are   normally  declared  and  paid  annually,  but  the  fund  may  make
distributions    on    a    more    frequent    basis    to    comply

                                                                      The   Fund

NOTES TO FINANCIAL STATEMENTS (CONTINUED)

with the distribution requirements of the Internal Revenue Code of 1986, as
amended (the "Code"). To the extent that net realized capital gain can be offset
by  capital  loss  carryovers,  if  any,  it  is  the  policy of the fund not to
distribute such gain.

(f) Federal income taxes: It is the policy of the fund to continue to qualify as
a  regulated  investment company, if such qualification is in the best interests
of  its  shareholders,  by complying with the applicable provisions of the Code,
and  to  make  distributions  of  taxable  income  sufficient to relieve it from
substantially all Federal income and excise taxes.

During  the  period  ended  December  31,  1999,  the fund increased accumulated
undistributed  investment  income-net  by $511,706, decreased paid-in capital by
$28,029  and  decreased  accumulated  net realized gain (loss) on investments by
$483,677. Net assets were not affected by this reclassification.

NOTE 2--Bank Line of Credit:

The  fund  participates  with  other  Dreyfus-managed  funds  in  a $500 million
redemption  credit  facility  (the  "Facility" ) to be utilized for temporary or
emergency  purposes,  including  the  financing  of  redemptions.  In connection
therewith, the fund has agreed to pay commitment fees on its pro rata portion of
the  Facility.  Interest  is  charged  to  the fund at rates based on prevailing
market  rates  in  effect  at  the  time  of borrowings. During the period ended
December 31, 1999, the fund did not borrow under the Facility.

NOTE 3--Management Fee and Other Transactions  With Affiliates:

     (a) Pursuant to a management agreement  ("Agreement") with the Manager, the
management  fee is  computed at the annual rate of .75 of 1% of the value of the
fund' s average daily net assets and is payable monthly.  The Agreement provides
that if in any full year the aggregate expenses of the fund, exclusive of taxes,
brokerage,  commitment  fees,  interest  on  borrowings  (which,  in the view of
Stroock & Stroock & Lavan LLP, counsel to the fund, also contemplates  dividends
on securities sold short), and extraordinary expenses, exceed 11_2% of the value
of the fund' s average net assets,  the fund may deduct from the  payments to be
made to the Manager,  or the Manager will bear such excess  expense.  During the
period ended December 31, 1999, there was no expense  reimbursement  pursuant to
the Agreement.

(b)  Under  the  Shareholder Services Plan, the fund pays the Distributor, at an
annual rate of .25 of 1% of the value of the fund's average daily net assets for
the  provision  of  certain services. The services provided may include personal
services  relating  to  shareholder  accounts,  such  as  answering  shareholder
inquiries  regarding  the  fund and providing reports and other information, and
services related to the maintenance of shareholder accounts. The Distributor may
make  payments  to Service Agents (a securities dealer, financial institution or
other  industry  professional)  in  respect  of  these services. The Distributor
determines  the  amounts  to  be paid to Service Agents. During the period ended
December  31,  1999, the fund was charged $1,552,725 pursuant to the Shareholder
Services Plan.

The  fund  compensates  Dreyfus Transfer, Inc., a wholly-owned subsidiary of the
Manager,   under  a  transfer  agency  agreement  for  providing  personnel  and
facilities  to  perform transfer agency services for the fund. During the period
ended  December 31, 1999, the fund was charged $343,409 pursuant to the transfer
agency agreement.

The  fund  compensates  Mellon under a custody agreement for providing custodial
services  for  the fund. During the period ended December 31, 1999, the fund was
charged $58,362 pursuant to the custody agreement.

(c)  Each  director  who  is  not  an  "affiliated person" as defined in the Act
receives from the fund an annual fee of $2,500 and an attendance fee of $500 per
meeting.  The  Chairman  of  the  Board  receives  an  additional  25%  of  such
compensation.

(d)  A  1% redemption fee is charged and retained by the fund on shares redeemed
within  six  months  following  the date of issuance, including redemptions made
through    the    use    of    the    fund's    exchange    privilege.

                                                                        The Fund

NOTES TO FINANCIAL STATEMENTS (CONTINUED)

(e) During the period ended December 31, 1999, the fund incurred total brokerage
commissions  of  $1,694,409,  of  which  $7,750  was  paid  to Dreyfus Brokerage
Services,   a   wholly-owned   subsidiary   of  Mellon  Financial  Corporation.

NOTE 4--Securities Transactions:

The  aggregate amount of purchases and sales of investment securities, excluding
short-term  securities,  during  the period ended December 31, 1999, amounted to
$566,231,393 and $776,743,577, respectively.

At December 31, 1999, accumulated net unrealized appreciation on investments was
$281,698,300,  consisting  of  $286,618,884  gross  unrealized  appreciation and
$4,920,584 gross unrealized depreciation.

At  December  31,  1999, the cost of investments for Federal income tax purposes
was substantially the same as the cost for financial reporting purposes (see the
Statement of Investments).


REPORT OF INDEPENDENT AUDITORS

Shareholders and Board of Directors
Dreyfus New Leaders Fund, Inc.

We  have audited the accompanying statement of assets and liabilities of Dreyfus
New  Leaders  Fund, Inc., including the statement of investments, as of December
31,  1999,  and the related statement of operations for the year then ended, the
statement  of changes in net assets for each of the two years in the period then
ended,  and  financial highlights for each of the years indicated therein. These
financial  statements  and  financial  highlights  are the responsibility of the
Fund' s  management.  Our  responsibility  is  to  express  an  opinion on these
financial statements and financial highlights based on our audits.

We conducted our audits in accordance with auditing standards generally accepted
in the United States. Those standards require that we plan and perform the audit
to  obtain  reasonable  assurance  about  whether  the  financial statements and
financial  highlights  are  free  of  material  misstatement.  An audit includes
examining,  on  a test basis, evidence supporting the amounts and disclosures in
the  financial  statements  and  financial  highlights.  Our procedures included
verification  by  examination of securities held by the custodian as of December
31,   1999  and  confirmation  of  securities  not  held  by  the  custodian  by
correspondence  with  others.  An  audit  also includes assessing the accounting
principles  used  and  significant  estimates  made  by  management,  as well as
evaluating  the  overall  financial  statement presentation. We believe that our
audits provide a reasonable basis for our opinion.

In  our  opinion,  the financial statements and financial highlights referred to
above  present  fairly,  in  all  material  respects,  the financial position of
Dreyfus  New  Leaders  Fund,  Inc.  at  December  31,  1999,  the results of its
operations  for  the  year then ended, the changes in its net assets for each of
the two years in the period then ended, and the financial highlights for each of
the indicated years, in conformity with accounting principles generally accepted
in the United States.


New York, New York

February 8, 2000

                                                                        The Fund


IMPORTANT TAX INFORMATION (Unaudited)

For  Federal  tax  purposes,  the  fund hereby designates $5.6930 per share as a
long-term  capital  gain  distribution of the $5.8100 per share paid on December
23,  1999  and  also  designates  $.1200  per  share as a long-term capital gain
distribution paid on March 31, 1999.

The  fund  also designates 100% of the ordinary dividends paid during the fiscal
year  ended December 31, 1999 as qualifying for the corporate dividends received
deduction.


                                                           For More Information

                        Dreyfus New Leaders Fund, Inc.

                        200 Park Avenue

                        New York, NY 10166

                        Manager

                        The Dreyfus Corporation

                        200 Park Avenue

                        New York, NY 10166

Custodian

Mellon Bank, N.A.

One Mellon Bank Center

Pittsburgh, PA 15258

Transfer Agent &

Dividend Disbursing Agent

Dreyfus Transfer, Inc.

P.O. Box 9671

Providence, RI 02940

Distributor

Premier Mutual Fund Services, Inc.

60 State Street

Boston, MA 02109

To obtain information:

BY TELEPHONE Call 1-800-645-6561

BY MAIL  Write to:  The Dreyfus Family of Funds 144 Glenn Curtiss Boulevard
Uniondale, NY 11556-0144

BY E-MAIL  Send your request to [email protected]

ON THE INTERNET  Information can be viewed online or downloaded from:

http://www.dreyfus.com

(c) 2000 Dreyfus Service Corporation                                   085AR9912


COMPARISON OF CHANGE IN VALUE OF $10,000
INVESTMENT IN DREYFUS NEW LEADERS FUND, INC.
AND THE RUSSELL 2500 INDEX

EXHIBIT A:

                                      DREYFUS
 PERIOD           RUSSELL 2500      NEW LEADERS
                    INDEX *          FUND, INC.

1/29/85                  10,000            10,000
12/31/85                 11,824            13,415
12/31/86                 13,240            15,093
12/31/87                 12,620            14,320
12/31/88                 15,489            17,663
12/31/89                 18,498            23,189
12/31/90                 15,746            20,440
12/31/91                 23,099            29,717
12/31/92                 26,838            32,519
12/31/93                 31,277            38,069
12/31/94                 30,947            38,012
12/31/95                 40,757            49,340
12/31/96                 48,514            57,880
12/31/97                 60,331            69,192
12/31/98                 60,562            66,460
12/31/99                 75,241            91,331

*Source: FactSet Research Systems, Inc.




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