ELAN CORP PLC
SC 13D, 1997-12-24
PHARMACEUTICAL PREPARATIONS
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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13D
                    Under the Securities Exchange Act of 1934

                                SANO CORPORATION
- -------------------------------------------------------------------------------
                                (Name of Issuer)

                          Common Stock, $.01 par value
- -------------------------------------------------------------------------------
                         (Title of Class of Securities)


- -------------------------------------------------------------------------------
                                 (CUSIP Number)

                                 Thomas G. Lynch
                              Elan Corporation, plc
                                  Lincoln House
                                  Lincoln Place
                                    Dublin 2
                                     Ireland
                                 353-1-709-4000
- -------------------------------------------------------------------------------

                                    Copy to:
                            William M. Hartnett, Esq.
                             Cahill Gordon & Reindel
                                 80 Pine Street
                            New York, New York 10005
- -------------------------------------------------------------------------------
       (Name, Address and Telephone Number of Person Authorized to Receive
                          Notices and Communications)

                                December 14, 1997
- -------------------------------------------------------------------------------
             (Date of Event which Requires Filing of this Statement)

If the filing person has previously filed a statement on Schedule 13G to report
the acquisition which is the subject of this Schedule 13D, and is filing this
schedule because of Rule 13d-1(b)(3) or (4), check the following box / /.

Note: Six copies of this statement, including all exhibits, should be filed with
the Commission. See Rule 13d-1(a) for other parties to whom copies are to be
sent.

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).



<PAGE>


                                  SCHEDULE 13D

- -------------------------------------------------------------------------------

CUSIP No.

- -------------------------------------------------------------------------------
1         NAME OF REPORTING PERSON
          S.S. OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSON (ENTITIES
             ONLY)
          Elan Corporation, plc
- -------------------------------------------------------------------------------
2         CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP    (a) / /
                                                              (b) / /
          N/A
- -------------------------------------------------------------------------------
3         SEC USE ONLY

- -------------------------------------------------------------------------------
4         SOURCE OF FUNDS

- -------------------------------------------------------------------------------
          OO
- -------------------------------------------------------------------------------
5         CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
          ITEMS 2(d) or 2(e)  N/A

- -------------------------------------------------------------------------------
6         CITIZENSHIP OR PLACE OF ORGANIZATION

          Ireland
- -------------------------------------------------------------------------------
                             7         SOLE VOTING POWER

        NUMBER OF                      1,545,271; See Item 6
         SHARES            ____________________________________________________
       BENEFICIALLY          8         SHARED VOTING POWER
         OWNED BY
           EACH
        REPORTING          ____________________________________________________
       PERSON WITH           9         SOLE DISPOSITIVE POWER


                           ----------------------------------------------------
                             10        SHARED DISPOSITIVE POWER

- -------------------------------------------------------------------------------
11        AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

            1,545,271
- -------------------------------------------------------------------------------
12        CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
          CERTAIN SHARES                                              / /
- -------------------------------------------------------------------------------
13        PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

            14.7%
- -------------------------------------------------------------------------------
14        TYPE OF REPORTING PERSON

          CO
- -------------------------------------------------------------------------------



<PAGE>


Item 1.  Security and Issuer.

     This statement relates to the Common Stock, $.01 par value (the "Common
Shares"), of Sano Corporation (the "Issuer"), an entity incorporated under the
laws of the State of Florida, whose principal executive offices are located at
3250 Commerce Parkway, Miramar, Florida, 33025.

Item 2.  Identity and Background.

     This statement is filed on behalf of Elan Corporation, plc ("Elan"), a
public limited company organized and existing under the laws of Ireland.

     Elan is an integrated worldwide drug delivery and biopharmaceutical
company. The principal business and office address of Elan is: Lincoln House,
Lincoln Place, Dublin 2, Ireland. Information as to the name, business address,
present principal occupation or employment and organization in which such
occupation or employment is conducted and citizenship of each director,
executive officer and controlling person of Elan is annexed hereto as Schedule A
and is incorporated herein by reference.

     Neither Elan nor, to the best of Elan's knowledge, any of the persons
listed on Schedule A hereto, has during the last five years (i) been convicted
in a criminal proceeding (excluding traffic violations or similar misdemeanors)
or (ii) been a party to a civil proceeding of a judicial or administrative body
of competent jurisdiction and as a result of such proceeding was or is subject
to a judgment, decree or final order enjoining future violations of, or
prohibiting or mandating activities subject to, federal or state securities laws
or finding any violation with respect to such laws.

Item 3.  Sources and Amount of Funds or Other Consideration.

     On December 14, 1997, Elan, Everglade Acquisition Corp. ("Everglade") and
the Issuer entered into an Agreement and Plan of Merger (the "Merger
Agreement"), which is filed herewith as Exhibit 1 and incorporated herein by
reference. Pursuant to the Merger Agreement and contingent upon the consummation
of the merger contemplated by the Merger Agreement, the stockholders of the
Issuer will receive .655 of an American Depository Share of Elan ("Elan ADS";
with each Elan ADS representing one Ordinary Share, par value 4 Irish pence, of
Elan) represented by American Depository Receipts of Elan, for each share of the
Common Stock of the Issuer they own at the time the merger becomes effective,
subject to certain agreed-upon adjustments. In addition, stock options of the
Issuer will be converted into stock options for Elan ADSs based upon the above
referenced exchange ratio.



<PAGE>


Item 4.  Purpose of Transaction.

     On December 14, 1997, Elan and the Issuer entered into the Merger
Agreement. Pursuant to the terms of the Merger Agreement, Everglade will be
merged with and into the Issuer, with the Issuer as the surviving entity and
becoming a wholly-owned subsidiary of Elan. The merger is structured as a
stock-for-stock merger intended to qualify as a tax-free reorganization within
the meaning of Section 368(a) of the Internal Revenue Code of 1986, as amended,
and accounted for as a purchase for financial reporting purposes. The
consummation of the merger is subject to various conditions, including but not
limited to, receiving the affirmative vote of a majority of the outstanding
equity securities of the Issuer and certain regulatory approvals. The
certificate of incorporation and by-laws of the Issuer in effect immediately
prior to the consummation of the merger shall be the certificate of
incorporation and by-laws of the surviving entity. The directors of Everglade
immediately prior to the effective time of the merger shall be the initial
directors of the surviving entity, and the officers of the Issuer immediately
prior to the effective time of the merger shall be the initial officers of the
surviving entity. Following consummation of the merger, Elan plans to apply to
the NASDAQ to delist the Common Stock of the Issuer and to file a Form 15 with
the Securities and Exchange Commission ("SEC") deregistering the Common Stock of
the Issuer pursuant to Section 12(g)(4) of the Securities Exchange Act of 1934,
as amended.

     The foregoing description of the Merger Agreement does not purport to be
complete and is qualified in its entirety by reference to the full text of the
Merger Agreement, which is filed herewith as Exhibit 1 and incorporated herein
by reference.

Item 5.  Interest in Securities of the Issuer.

     (a) By virtue of the Voting Agreement described below, Elan may be deemed
to be the beneficial owner of approximately 1,545,271 shares, or approximately
14.7%, of the Issuer's common stock. See Item 6 below.

     (b) See Item 6 below.

     (c) N/A

     (d) N/A

     (e) N/A

     The filing of this statement does not constitute an admission by Elan that
it is the beneficial owner of any shares of the Issuer. Elan is making this
filing because of the possibility that it may be deemed to be the beneficial
owner of certain shares of the Issuer.


<PAGE>

Item 6.  Contracts, Arrangements, Understandings
         or Relationships with Respect to
         Securities of the Issuer.

     See Item 4.

     On December 14, 1997, as a condition to Elan's willingness to enter into
the Merger Agreement, Reginald Hardy and Marc Watson (the "Stockholders"), and
Elan entered into a voting agreement (the "Voting Agreement") whereby each of
the Stockholders agrees, until the earliest of the termination of the Merger
Agreement, consummation of the merger, termination of the Voting Agreement by
mutual agreement of the parties thereto or the termination by Elan of the Voting
Agreement and subject to his obligations to faithfully discharge his duty as a
director of the Issuer, to cause the shares of the Issuer common stock which he
owns to be voted in favor of the Merger Agreement and the transactions
contemplated thereby. The Voting Agreement is filed herewith as Exhibit 2 and is
incorporated herein by reference. Messrs. Hardy and Watson own an aggregate of
approximately 1,545,271 shares, or approximately 14.7% of the Issuer's common
stock.

Item 7.  Items to be Filed as Exhibits.

Exhibit  1 Agreement and Plan of Merger, dated as of December 14, 1997,
           by and among Sano Corporation, Elan Corporation, plc and
           Everglade Acquisition Corp.

Exhibit  2 Voting Agreement, dated as of December 14, 1997, by and
           among Elan Corporation, plc, Reginald Hardy and Marc Watson.



<PAGE>



                                    Signature


     The undersigned certifies that, after reasonable inquiry and to the best of
its knowledge and belief, the information set forth in this Schedule 13D is
true, complete and correct.

December 24, 1997

                              ELAN CORPORATION, plc


                              By: /s/ Thomas G. Lynch
                                 ---------------------------------------
                                 Name:  Thomas G. Lynch
                                 Title: Executive Vice President and
                                          Chief Financial Officer




<PAGE>


                                   Schedule A

     The (a) name, (b) business address, (c) principal occupation or employment
and the organization in which such occupation or employment is conducted and (d)
citizenship of each director (other than Messrs. Armen, Balog, Boushel, Crowley,
Gillespie, McIntyre, Panoz, Selkoe and Thornburgh) and officer of Elan
Corporation, plc are set forth in the following table:

1.       (a)      Donal J. Geaney
         (b)      Lincoln House, Lincoln Place, Dublin 2, Ireland
         (c)      Chairman of the Board and Chief Executive Officer of Elan
         (d)      Ireland

2.       (a)      John Groom
         (b)      Lincoln House, Lincoln Place, Dublin 2, Ireland
         (c)      Director, President and Chief Operating Officer of Elan
         (d)      United Kingdom

3.       (a)      Thomas G. Lynch
         (b)      Lincoln House, Lincoln Place, Dublin 2, Ireland
         (c)      Director, Executive Vice President and Chief Financial
                  Officer of Elan
         (d)      United Kingdom

4.       (a)      Michael D. Coffee
         (b)      800 Gateway Boulevard, South San Francisco, CA 94080
                  (c)      President and Chief Operating Officer, Athena
         (d)      United States

5.       (a)      William F. Daniel
         (b)      Lincoln House, Lincoln Place, Dublin 2, Ireland
         (c)      Group Vice President, Finance, and Group Controller of Elan
         (d)      Ireland

6.       (a)      John Devane, Ph.D.
         (b)      Lincoln House, Lincoln Place, Dublin 2, Ireland
         (c)      Executive Vice President, Research and Development, EPT
         (d)      Ireland

7.       (a)      Ronald Kartzinel, M.D., Ph.D.
         (b)      1300 Gould Drive, Gainesville, Georgia  30501
         (c)      Vice President, Compliance of Elan
         (d)      United States

8.       (a)      Ivan M. Liederburg, Ph.D., M.D.
         (b)      800 Gateway Boulevard, South San Francisco, CA 94080
                  (c)      Vice President, Research, Athena
         (d)      United States


<PAGE>

9.       (a)      Seamus Mulligan
         (b)      Lincoln House, Lincoln Place, Dublin 2, Ireland
         (c)      President, EPT
         (d)      Ireland

10.      (a)      Lisabeth Murphy
         (b)      800 Gateway Boulevard, South San Francisco, CA 94080
         (c)      Vice President and General Counsel of Elan
         (d)      United States

11.      (a)      Mark A. Pearson
         (b)      Lincoln House, Lincoln Place, Dublin 2, Ireland
         (c)      Secretary of Elan
         (d)      Ireland

12.      (a)      Stephen Seiler
         (b)      c/o Elan Corporation plc, Lincoln House, Lincoln Place,
                  Dublin 2, Ireland
         (c)      Executive Vice President, Planning, Investment and Development
         (d)      United States

13.      (a)      Paulette E. Setler, M.D.
         (b)      800 Gateway Boulevard, South San Francisco, CA 94080
         (c)      Vice President and Chief Scientific Officer of Elan
         (d)      United States

14.      (a)      Jan D. Wallace, M.D.
         (b)      800 Gateway Boulevard, South San Francisco, CA 94080
         (c)      Vice President, Clinical and Regulatory Affairs, Athena
         (d)      United States

     The (a) name, (b) business address, (c) principal occupation or employment
and the organization in which such occupation or employment is conducted and (d)
citizenship of each director (other than Messrs. Geaney, Groom, and Lynch) are
set forth in the following table:

1.       (a)      Garo Armen, Ph.D.
         (b)      30 Rockefeller Plaza, Suite 4220, New York, New York  10112
         (c)      Chairman of the Board and Chief Executive Officer of
                  Antigenics Inc.
         (d)      United States

2.       (a)      James Balog
         (b)      2205 N. Southwinds Blvd., Unit No. 307, Vero Beach,
                  Florida  32963
         (c)      Retired
         (d)      United States

3.       (a)      Brendon Boushel

<PAGE>

         (b)      9 Upper Mount Street, Dublin 2, Ireland
         (c)      Attorney with the law firm of Overend McCarron & Gibbons
         (d)      Ireland

4.       (a)      Laurence G. Crowley
         (b)      c/o Elan Corporation, plc, Lincoln House, Lincoln Place,
                  Dublin 2, Ireland
         (c)      Deputy Governor of the Bank of Ireland, Executive Chairman
                  of Graduate Business School of University College, Dublin
         (d)      Ireland

5.       (a)      Alan R.Gillespie, Ph.D.
         (b)      c/o Elan Corporation, plc, Lincoln House, Lincoln Place,
                  Dublin 2, Ireland
         (c)      Managing Director, Goldman Sachs International
         (d)      United Kingdom

6.       (a)      Kevin McIntyre, M.D.
         (b)      160 Commonwealth Avenue, Suite 801, Boston,
                  Massachusetts  02116
         (c)      Associate Clinical Professor of Medicine at Harvard Medical
                  School
         (d)      United States

7.       (a)      Donald E. Panoz
         (b)      c/o Elan Corporation, plc, Lincoln House, Lincoln Place,
                  Dublin 2, Ireland
         (c)      Executive Chairman of Fountainhead Holdings Ltd. and
                  Fountainhead Development Corp.
         (d)      Ireland

8.       (a)      Dennis J.Selkoe, M.D.
         (b)      c/o Elan Corporation, plc, Lincoln House, Lincoln Place,
                  Dublin 2, Ireland
         (c)      Professor of Neurology and Neuroscience at Harvard Medical
                  School
         (d)      United States

9.       (a)      Richard Thornburgh
         (b)      c/o Elan Corporation, plc, Lincoln House, Lincoln Place,
                  Dublin 2, Ireland
         (c)      Counsel to the law firm of Kirkpatrick & Lockhart LLP.
         (d)      United States



<PAGE>





Exhibit Index

1.   Agreement and Plan of Merger dated as of December 14, 1997, by and among
     Sano Corporation, Elan Corporation, plc. and Everglade Acquisition Corp.

2.   Voting Agreement, dated as of December 14, 1997, by and among Elan
     Corporation, plc., Reginald Hardy and Marc Watson.




                          AGREEMENT AND PLAN OF MERGER


                                      Among


                             ELAN CORPORATION, PLC.


                           EVERGLADE ACQUISITION CORP.


                                       and


                                SANO CORPORATION








                             Dated December 14, 1997





<PAGE>

     AGREEMENT AND PLAN OF MERGER dated December 14, 1997 (this "Agreement")
among Elan Corporation, plc., a public company organized under the laws of
Ireland ("Parent"), Everglade Acquisition Corp., a Delaware corporation and a
wholly owned subsidiary of Parent ("Merger Sub"), and Sano Corporation, a
Florida corporation (the "Company").

     WHEREAS, the parties hereto desire to cause the Company, upon the terms and
subject to the conditions of this Agreement and in accordance with the Florida
Business Corporation Act of the State of Florida ("Florida Law") and the
Delaware General Corporation Law of the State of Delaware ("Delaware Law"), to
merge with and into Merger Sub (the "Merger");

     WHEREAS, the Board of Directors of the Company has (i) determined that the
Merger is fair to the holders of shares of Company Common Stock (as such term is
defined in Section 2.01) and is in the best interests of such shareholders and
(ii) approved this Agreement and the transactions contemplated hereby and
recommended unanimously that the holders of shares of Company Common Stock
approve and adopt this Agreement;

     WHEREAS, the Board of Directors of Parent has determined that the Merger is
in the best interests of Parent and its stockholders and, as sole stockholder of
Merger Sub, has approved and adopted this Agreement and the transactions
contemplated hereby;

     WHEREAS, for federal income tax purposes, it is intended that the Merger
shall qualify as a reorganization under the provisions of Section 368(a) of the
United States Internal Revenue Code of 1986, as amended (the "Code"); and

     NOW, THEREFORE, in consideration of the foregoing and the mutual covenants
and agreements herein contained and intending to be legally bound hereby,
Parent, Merger Sub and the Company hereby agree as follows:


                                    ARTICLE I

                                   THE MERGER


     SECTION 1.01. The Merger. Upon the terms and subject to the conditions set
forth in Article VII, and in 


<PAGE>
                                      -2-


accordance with Section 607.1101 of Florida Law and the applicable provision of
Delaware Law, at the Effective Time (as defined below), Merger Sub shall be
merged with and into the Company. As a result of the Merger, the separate
corporate existence of Merger Sub shall cease, and the Company shall be the
surviving corporation of the Merger (the "Surviving Corporation").

     SECTION 1.02. Effective Time; Closing. As promptly as practicable, and in
no event later than five business days after the satisfaction or, if
permissible, waiver of the conditions set forth in Article VII (other than those
conditions that can only be satisfied on the Closing Date (as defined below)),
the parties hereto shall cause the Merger to be consummated by filing articles
of merger (the "Articles of Merger") with the Secretary of State of the State of
Florida, in such form as is required by, and executed in accordance with,
Section 607.1101 of Florida Law in addition to any filings that may be required
under Delaware Law. The term "Effective Time" means the date and time of the
filing of the Articles of Merger with the Secretary of State of the State of
Florida and any required filings with the Secretary of State of the State of
Delaware (or such later time as may be agreed by the parties hereto and
specified in the Articles of Merger). Immediately prior to the filing of the
Articles of Merger and any required filings under Delaware Law, a closing will
be held at the offices of Cahill Gordon & Reindel, 80 Pine Street, New York, New
York (or such other place as the parties may agree) (the date on which such
closing takes place being the "Closing Date").

     SECTION 1.03. Effect of the Merger. At the Effective Time, the effect of
the Merger shall be as provided in the applicable provisions of Florida Law and
Delaware Law. Without limiting the generality of the foregoing, and subject
thereto, at the Effective Time, all the property, rights, privileges, powers and
franchises of the Company and Merger Sub shall vest in the Surviving
Corporation, and all debts, liabilities, obligations, restrictions, disabilities
and duties of each of the Company and Merger Sub shall become the debts,
liabilities, obligations, restrictions, disabilities and duties of the Surviving
Corporation.

     SECTION 1.04. Articles of Incorporation; By-laws.

     (a) Subject to the terms of Section 6.06, at the Effective Time, the
Articles of Incorporation of the Surviving 


<PAGE>
                                      -3-


Corporation shall be the Articles of Incorporation of the Company as in effect
immediately prior to the Effective Time.

     (b) Subject to the terms of Section 6.06, at the Effective Time, the
By-laws of the Company, as in effect immediately prior to the Effective Time,
shall be the By-laws of the Surviving Corporation until thereafter amended as
provided by law, the Articles of Incorporation of the Surviving Corporation and
such By-laws.

     SECTION 1.05. Directors and Officers. The directors of Merger Sub
immediately prior to the Effective Time shall be the directors of the Surviving
Corporation, each to hold office in accordance with the Articles of
Incorporation and By-laws of the Surviving Corporation, and the officers of the
Company immediately prior to the Effective Time shall be the initial officers of
the Surviving Corporation, in each case until their respective successors are
duly elected or appointed and qualified.


                                   ARTICLE II

               CONVERSION OF SECURITIES; EXCHANGE OF CERTIFICATES


     SECTION 2.01. Capital Stock of Merger Sub. As of the Effective Time, by
virtue of the Merger and without any action on the part of the holder of any
shares of Company Common Stock, par value $.01 per share (the "Company Common
Stock"), or any shares of capital stock of Merger Sub, all shares of common
stock, par value $.01 per share, of Merger Sub issued and outstanding
immediately prior to the Effective Time shall be converted into and become such
number of fully paid and nonassessable shares of common stock, par value $.01
per share, of the Surviving Corporation as shall equal the sum of the number of
shares of Company Common Stock outstanding immediately prior to the Effective
Time and the number of shares of Company Common Stock underlying options,
warrants, calls, subscriptions or other rights or other agreements or
commitments of the Company assumed by Parent.

     SECTION 2.02. Parent Owned Stock. As of the Effective Time, by virtue of
the Merger and without any action on the part of the holder of any shares of
Company Common Stock or any shares of capital stock of Merger Sub, each share of
Company Common Stock issued and held immediately prior to the Effective Time
that is owned by Parent, Merger Sub or any other 


<PAGE>
                                      -4-


wholly-owned subsidiary of Parent shall automatically be cancelled and retired
and shall cease to exist, and no consideration shall be delivered in exchange
therefor.

     SECTION 2.03. Conversion of Company Common Stock. (a) As of the Effective
Time, by virtue of the Merger and without any action on the part of the holder
of any shares of Company Common Stock or any shares of capital stock of Merger
Sub, subject to Section 2.04(f), each share of Company Common Stock issued and
outstanding immediately prior to the Effective Time (other than shares to be
issued or cancelled in accordance with Sections 2.01 and 2.02, respectively)
shall be converted into the right to receive a specified percentage (the
"Specified Percentage") of an American Depositary Share evidenced by American
Depositary Receipts ("ADRs") (rounding the result to the nearest one thousandth
of a share) of Parent (a "Parent ADS") (each such Parent ADS representing one
Ordinary Share ("Parent Ordinary Share"), par value 4 Irish pence, of Parent)
(the "Merger Consideration"); for the purposes hereof, if the Average Parent
Trading Price (as defined below) is between $49.1625 and $59.1625, the Specified
Percentage shall equal the quotient of $35.50 divided by the Average Parent
Trading Price; if the Average Parent Trading Price is greater than $59.1625,
then the Specified Percentage shall be .6000; and if the Average Parent Trading
Price is below $49.1625, then the Specified Percentage shall be .7221. In the
event that between the date hereof and the Effective Time, the outstanding
Parent ADSs (or underlying Parent Ordinary Shares) shall have been changed into
a different number of shares or a different class, by reason of any stock
dividend, subdivision, reclassification, recapitalization, split, combination or
exchange of shares, the Merger Consideration shall be correspondingly adjusted
to the extent appropriate to reflect such stock dividend, subdivision,
reclassification, recapitalization, split, combination or exchange of shares.

     The "Average Parent Trading Price" means the average of the closing prices
per share of Parent ADSs on the New York Stock Exchange, Inc. (the "NYSE")
Composite Transaction Tape for the five consecutive trading days ending on the
trading day prior to the Closing Date as reported in the Wall Street Journal or
if not reported therein, any other authorized source for such information.

     SECTION 2.04. Exchange of Certificates. (a) Exchange Agent. From and after
the Effective Time, (i) Parent shall make available to a bank or trust company
designated by 


<PAGE>
                                      -5-


Parent who shall be the depositary under Parent's ADR program (the "Exchange
Agent"), for the benefit of the holders of shares of Company Common Stock, for
exchange in accordance with this Article II through the Exchange Agent,
certificates evidencing a sufficient number of Parent Ordinary Shares as would
permit the Exchange Agent to issue such number of Parent ADSs issuable to
holders of Company Common Stock pursuant to Section 2.03 (such certificates for
Parent ADSs, together with any dividends or distributions with respect thereto,
being hereinafter referred to as the "Exchange Fund"). As promptly as
practicable after the Effective Time, Parent shall cause the Exchange Agent to
deliver the Parent ADSs contemplated to be issued pursuant to Section 2.03 out
of the Exchange Fund in accordance with the procedures specified in this Section
2.04. Except as contemplated by Section 2.04(g) hereof, the Exchange Fund shall
not be used for any other purpose.

     (b) Exchange Procedures. As promptly as practicable after the Effective
Time, Parent shall cause the Exchange Agent to mail to each record holder of a
certificate or certificates which immediately prior to the Effective Time
represented outstanding shares of Company Common Stock (the "Certificates") (i)
a letter of transmittal (which shall be in customary form and shall specify that
delivery shall be effected, and risk of loss and title to the Certificates shall
pass, only upon proper delivery of the Certificates to the Exchange Agent) and
(ii) instructions for use in effecting the surrender of the Certificates in
exchange for the Merger Consideration.

     (c) Exchange of Certificates. Upon surrender to the Exchange Agent of a
Certificate for cancellation, together with such letter of transmittal, duly
executed and completed in accordance with the instructions thereto, and such
other documents as may be reasonably required pursuant to such instructions, the
holder of such Certificate shall be entitled to receive in exchange therefor a
certificate representing that number of whole shares of Parent ADSs, if any, to
which such holder is entitled pursuant to this Article II (including any cash in
lieu of any fractional Parent ADSs to which such holder is entitled pursuant to
Section 2.04(f) and any dividends or other distributions to which such holder is
entitled pursuant to Section 2.04(d) (together, the "Additional Payments")), and
the Certificate so surrendered shall forthwith be cancelled. In the event of a
transfer of ownership of shares of Company Common Stock which is not registered
in the transfer records of the Company, the applicable Merger Consideration and
Additional Payments, if any, may be issued to a transferee if the Certificate
representing such shares of Company Common Stock is pre-


<PAGE>
                                      -6-


sented to the Exchange Agent, accompanied by all documents required to evidence
and effect such transfer and by evidence that any applicable stock transfer
taxes have been paid. Until surrendered as contemplated by this Section 2.04,
each Certificate shall be deemed at all times after the Effective Time to
represent only the right to receive upon such surrender the applicable Merger
Consideration with respect to the shares of Company Common Stock formerly
represented thereby and Additional Payments, if any.

     (d) Distributions with Respect to Unsurrendered Certificates. No dividends
or other distributions declared or made after the Effective Time with respect to
Parent ADSs (or underlying Parent Ordinary Shares) with a record date after the
Effective Time shall be paid to the holder of any unsurrendered Certificate with
respect to the Parent ADSs the holder thereof is entitled to receive upon
surrender thereof, and no cash payment in lieu of any fractional shares shall be
paid to any such holder pursuant to Section 2.04(f), until the holder of such
Certificate shall surrender such Certificate. Subject to the effect of escheat,
tax or other applicable Laws, following surrender of any such Certificate, there
shall be paid to the holder of the certificates representing whole shares of
Parent ADSs issued in exchange therefor, without interest, (i) promptly, the
amount of any cash payable with respect to a fractional Parent ADS to which such
holder is entitled pursuant to Section 2.04(f) and the amount of dividends or
other distributions with a record date after the Effective Time and theretofore
paid with respect to such whole shares of Parent ADSs, and (ii) at the
appropriate payment date, the amount of dividends or other distributions, with a
record date after the Effective Time but prior to surrender and a payment date
occurring after surrender, payable with respect to such whole Parent ADSs. After
the Effective Time, each outstanding Certificate which theretofore represented
shares of Company Common Stock shall, until surrendered for exchange in
accordance with this Section 2.04, be deemed for all purposes to evidence
ownership of the number of shares of Parent ADSs into which the shares of
Company Common Stock (which, prior to the Effective Time, were represented
thereby) shall have been so converted.

     (e) No Further Rights in Company Common Stock. At the Effective Time all
outstanding shares of Company Common Stock, by virtue of the Merger and without
any action on the part of the holders thereof, shall no longer be outstanding
and shall be cancelled and retired and shall cease to exist, and each holder of
a certificate representing any such shares of Company Common Stock shall
thereafter cease to have any rights 


<PAGE>
                                      -7-


with respect to such shares of Company Common Stock, except the right to receive
the Merger Consideration for such shares of Company Common Stock. All Parent
ADSs issued upon conversion of the shares of Company Common Stock in accordance
with the terms hereof (including any cash paid pursuant to Section 2.04(d) or
(f)) shall be deemed to have been issued in full satisfaction of all rights
pertaining to such shares of Company Common Stock.

     (f) No Fractional Shares. No certificates or scrip representing fractional
shares of Parent ADSs shall be issued upon the surrender for exchange of
Certificates, and such fractional share interests will not entitle the owner
thereof to vote or to any other rights of a holder of Parent ADSs. Each holder
of a fractional share interest shall be paid an amount in cash equal to the
product obtained by multiplying (i) such fractional share interest to which such
holder (after taking into account all fractional share interests then held by
such holder) would otherwise be entitled by (ii) the Average Parent Trading
Price. As promptly as practicable after the determination of the amount of cash,
if any, to be paid to holders of fractional share interests, the Exchange Agent
shall so notify Parent, and Parent shall deposit such amount with the Exchange
Agent and shall cause the Exchange Agent to forward payments to such holders of
fractional share interests subject to and in accordance with the terms of
Sections 2.04(b), (c) and (d).

     (g) Termination of Exchange Fund. Any portion of the Exchange Fund which
remains undistributed to the holders of Company Common Stock for six months
after the Effective Time shall be delivered to Parent, upon demand, and any
holders of Company Common Stock who have not theretofore complied with this
Article II shall thereafter look only to Parent for the applicable Merger
Consideration and any Additional Payments to which they are entitled. Any
portion of the Exchange Fund remaining unclaimed by holders of shares of Company
Common Stock as of a date which is immediately prior to such time as such
amounts would otherwise escheat to or become property of any government entity
shall, to the extent permitted by applicable Law, become the property of Parent
free and clear of any claims or interest of any person previously entitled
thereto.

     (h) No Liability. None of the Exchange Agent, Parent or the Surviving
Corporation shall be liable to any holder of Certificates for any shares of
Parent ADSs (or dividends or distributions with respect thereto), or cash
delivered to a public official pursuant to any abandoned property, escheat or
similar law.



<PAGE>
                                      -8-



     (i) Withholding Rights. Each of the Surviving Corporation and Parent shall
be entitled to deduct and withhold from the consideration otherwise payable
pursuant to this Agreement to any holder of Certificates such amounts as it is
required to deduct and withhold with respect to the making of such payment under
the Code, or any provision of state, local or foreign tax law. To the extent
that amounts are so withheld by the Surviving Corporation or Parent, as the case
may be, such withheld amounts shall be treated for all purposes of this
Agreement as having been paid to the holder of the Certificates in respect of
which such deduction and withholding was made by the Surviving Corporation or
Parent, as the case may be.

     (j) Lost Certificates. If any Certificate shall have been lost, stolen or
destroyed, upon the making of an affidavit of that fact by the person claiming
such Certificate to be lost, stolen or destroyed and, if required by the
Surviving Corporation or Parent, the posting by such person of a bond, in such
reasonable amount as the Surviving Corporation or Parent may direct, as
indemnity against any claim that may be made against it with respect to such
Certificate, the Exchange Agent will issue in exchange for such lost, stolen or
destroyed Certificate the applicable Merger Consideration and Additional
Payments, if any.

     (k) Further Assurances. If, at any time after the Effective Time, the
Surviving Corporation shall consider or be advised that any deeds, bills of
sale, assignments, assurances or any other actions or things are reasonably
necessary to vest, perfect or confirm of record or otherwise in the Surviving
Corporation its right, title or interest in, to or under any of the rights,
properties or assets of either of the Merger Sub or the Company acquired or to
be acquired by the Surviving Corporation as a result of, or in connection with,
the Merger or otherwise to carry out this Agreement, the officers of the
Surviving Corporation shall be authorized to execute and deliver, in the name
and on behalf of each of the Merger Sub and the Company or otherwise, all such
deeds, bills of sale, assignments and assurances and to take and do, in such
names and on such behalves or otherwise, all such other actions and things as
may be reasonably necessary to vest, perfect or confirm any and all right, title
and interest in, to and under such rights, properties or assets in the Surviving
Corporation or otherwise to carry out the purposes of this Agreement.

     SECTION 2.05. Stock Transfer Books. At the Effective Time, the stock
transfer books of the Company shall be closed and there shall be no further
registration of 



<PAGE>
                                      -9-


transfers of shares of Company Common Stock thereafter on the records of the
Company. On or after the Effective Time, any Certificates presented to the
Exchange Agent or Parent for any reason shall be converted into the applicable
Merger Consideration and Additional Payments, if any.

     SECTION 2.06. Company Stock Options. (a) Each outstanding option to
purchase shares of Company Common Stock listed in Section 3.03 of the Company
Disclosure Schedule (as defined below) issued pursuant to the Company's 1993 and
1995 Stock Option Plans (the "Option Plans"), or otherwise set forth in Section
3.03 of the Company Disclosure Schedule (each an "Option"), whether or not
vested or exercisable, shall be assumed by Parent and shall constitute an option
to acquire, on the same terms and conditions (except as set forth herein) as
were applicable under such Option, the number of Parent ADSs rounded up or down
to the nearest whole share equal to the product of the Specified Percentage
multiplied by the number of shares of Company Common Stock subject to such
Option immediately prior to the Effective Time, at a price per share equal to
the aggregate exercise price for the shares of Company Common Stock subject to
such Option divided by the number of Parent ADSs that would be purchasable
pursuant to such Option ("Assumed Options"); provided, further, that from and
after the Effective Time the Assumed Options shall be vested and fully
exercisable. As soon as practicable after the Effective Time, Parent shall
deliver to holders of Assumed Options an appropriate notice setting forth such
holders' rights pursuant thereto and shall deliver appropriate option agreements
representing the right to acquire Parent ADSs on the same terms and conditions
as contained in the Options (subject to any adjustments required by the
preceding sentence), upon surrender of the outstanding Options. Parent shall
comply with the terms of the Option Plan as they apply to the Assumed Options.
Parent shall take all corporate action necessary to reserve for issuance a
sufficient number of shares of Parent ADSs for delivery upon exercise of the
Assumed Options in accordance with this Section 2.06. Parent shall file a
registration statement on Form S-8 (or any successor form) or another
appropriate form, effective as of the Effective Time, with respect to Parent
ADSs subject to Assumed Options and shall use commercially reasonable efforts to
maintain the effectiveness of such registration statement or registration
statements (and maintain the current status of the prospectus or prospectuses
contained therein) for so long as the Assumed Options remain outstanding. A
holder of an Assumed Option may exercise such Assumed Option in whole or in part
in accordance with its terms by delivering a properly executed notice of
exercise to Parent, 



<PAGE>
                                      -10-


together with the consideration therefor and the federal withholding tax
information, if any, required in accordance with the related Option Plan.

     (b) At the Effective Time, Parent shall grant options under Parent's
existing stock option plans to purchase Parent ADSs to Company employees as set
forth on Exhibit 2.06.


                                   ARTICLE III

                  REPRESENTATIONS AND WARRANTIES OF THE COMPANY


     Except as disclosed in a separate disclosure schedule referring to the
Sections contained in this Agreement, which has been delivered by the Company to
Parent prior to the execution of this Agreement (the "Company Disclosure
Schedule"), the Company hereby represents and warrants to the Parent and Merger
Sub that:

     SECTION 3.01. Organization and Qualification; Subsidiaries. The Company is
a corporation duly incorporated, validly existing and in good standing under the
laws of the jurisdiction of its incorporation and has the requisite corporate
power and authority and all necessary governmental approvals to own, lease and
operate its properties and to carry on its business as it is now being
conducted, except where the lack of such power, authority and approval would
not, individually or in the aggregate, have a Company Material Adverse Effect
(as defined below). The Company is duly qualified or licensed as a foreign
corporation to do business, and is in good standing, in each jurisdiction where
the character of the properties owned, leased or operated by it or the nature of
its business makes such qualification or licensing necessary, except for such
failures to be so qualified or licensed and in good standing that would not,
individually or in the aggregate, have a Company Material Adverse Effect. The
term "Company Material Adverse Effect" means any change in, or effect on, the
Company, which is, or would reasonably be expected in the future to be,
materially adverse to the operations, general affairs, management, business,
condition (financial or otherwise) assets or liabilities or earnings or results
of operations of the Company. The Company does not directly or indirectly own
any equity or similar interest in, or any interest convertible into or
exchangeable or exercisable for any equity or similar 



<PAGE>
                                      -11-


interest in, any corporation, partnership, limited liability company, joint
venture or other business association or entity.

     SECTION 3.02. Articles of Incorporation and By-laws. The Company has
heretofore furnished to Parent complete and correct copies of its Amended and
Restated Articles of Incorporation (the "Articles of Incorporation") and
By-laws, each as amended to date. Such Articles of Incorporation and By-laws are
in full force and effect. The Company is not in violation of any provision of
its Articles of Incorporation or By-laws.

     SECTION 3.03. Capitalization. The authorized capital stock of the Company
consists of 25,000,000 shares of Company Common Stock and 5,000,000 shares of
Preferred Stock par value $0.01 per share (the "Company Preferred Stock"). No
shares of Company Preferred Stock are outstanding. As of September 30, 1997,
there are 10,511,831 shares of Company Common Stock outstanding. Section 3.03 of
the Company Disclosure Schedule identifies and describes the number of shares of
Company Common Stock to be received upon exercise or conversion and the exercise
or conversion price of all outstanding options (the "Company Common Stock
Equivalents"). All of the Company Common Stock Equivalents have been issued
pursuant to the Company's Option Plans and may be assumed by Parent in
accordance with Section 2.06 without consent of the holders thereof (or any such
consent as may be required shall have been obtained and delivered to Parent not
later than five days from the date of this Agreement). Except for the Company
Common Stock Equivalents there are no existing options, warrants, calls,
subscriptions, or other rights or other agreements or commitments obligating the
Company to issue, transfer or sell any shares of capital stock of the Company or
any other securities convertible into or evidencing the right to subscribe for
any such shares. There are no outstanding stock appreciation rights with respect
to the capital stock of the Company. All issued and outstanding shares of
Company Common Stock are duly authorized and validly issued, fully paid,
non-assessable and free of preemptive rights with respect thereto.

     SECTION 3.04. Authority Relative to this Agreement. The Company has all
necessary corporate power and authority to execute and deliver this Agreement,
to perform its obligations hereunder and to consummate the Merger. The execution
and delivery of this Agreement by the Company and the consummation by the
Company of the Merger have been duly and validly authorized by all necessary
corporate action and no other 



<PAGE>
                                      -12-


corporate proceedings on the part of the Company are necessary to authorize this
Agreement or to consummate the Merger (other than, with respect to the Merger,
the adoption of this Agreement by the holders of a majority of the shares of
Company Common Stock and the filing and recordation of appropriate merger
documents as required by Florida Law). This Agreement has been duly and validly
executed and delivered by the Company and, assuming the due authorization,
execution and delivery by Parent and Merger Sub, constitutes a legal, valid and
binding obligation of the Company, enforceable against the Company in accordance
with its terms, subject to bankruptcy, insolvency, fraudulent transfer,
reorganization, moratorium and similar laws of general applicability relating to
or affecting creditors' rights and to general equity principles.

     SECTION 3.05. No Conflict; Required Filings and Consents.

     (a) The execution and delivery of this Agreement by the Company does not,
and the performance of this Agreement by the Company and to the Knowledge of the
Company the exercise by the Parent and the Merger Sub of full rights to own and
operate the business of the Company will not, (i) conflict with or violate the
Articles of Incorporation or By-laws of the Company, (ii) conflict with or
violate any domestic (federal, state or local) or foreign law, rule, regulation,
order, judgment or decree (collectively, "Laws") applicable to the Company or by
which any property or asset of the Company is bound or affected, except for such
conflicts or violations that, individually or in the aggregate, are not
reasonably likely to have a Company Material Adverse Effect, or (iii) result in
any breach of or constitute a default (or an event which with notice or lapse of
time or both would become a default) under, or give to others any right of
termination, amendment, acceleration or cancellation of, or result in the
creation of a lien or other encumbrance on any property or asset of the Company
pursuant to, any note, bond, mortgage, indenture, contract, agreement, lease,
license, permit, franchise or other instrument or obligation to which the
Company is a party or by which the Company or any property or asset of the
Company is bound or affected, except for any such breaches, defaults or other
occurrences that, individually or in the aggregate, would not have a Company
Material Adverse Effect or impair the Company's ability to consummate the Merger
or, to the Knowledge of the Company, the exercise by the Parent and the Merger
Sub of full rights to own and operate the business of the Company.



<PAGE>
                                      -13-


     (b) The execution and delivery of this Agreement by the Company do not, and
the performance of this Agreement by the Company will not, require any consent,
approval, authorization or permit of, or filing with or notification to, any
governmental or regulatory authority, domestic, foreign or supranational, except
(i) for applicable requirements, if any, of the Securities Exchange Act of 1934,
as amended (the "Exchange Act"), the Securities Act of 1933, as amended (the
"Securities Act"), state securities or "blue sky" laws ("Blue Sky Laws"), state
takeover laws, the pre-merger notification requirements of the Hart-Scott-Rodino
Antitrust Improvements Act of 1976, as amended, and the rules and regulations
thereunder (the "HSR Act"), and filing and recordation of appropriate merger
documents as required by Florida Law, Delaware Law and the rules of the National
Association of Securities Dealers ("NASD") and (ii) where failure to obtain such
consents, approvals, authorizations or permits, or to make such filings or
notifications, individually or in the aggregate, is not reasonably likely to
have a Company Material Adverse Effect.

     SECTION 3.06. Compliance with Laws; Permits. (a) The Company is not in
violation of any statute, law, ordinance, regulation, rule or order of any
foreign, federal, state or local government or any other governmental department
or agency, or any judgment, decree or order of any court, applicable to its
business or operations, except where any such violations or failures to comply
would not, individually or in the aggregate, have a Company Material Adverse
Effect. The Company has all permits, licenses and franchises from governmental
agencies required to conduct its business as now being conducted, except for
such permits, licenses and franchises the absence of which would not,
individually and in the aggregate, have a Company Material Adverse Effect.

     (b) To the best of the Company's knowledge, as to each product subject to
FDA's jurisdiction under the Federal Food, Drug and Cosmetic Act ("FDCA") and
the jurisdiction of the Drug Enforcement Agency under the Comprehensive Drug
Abuse Prevention and Control Act of 1970 ("CSA") which is manufactured, tested,
distributed, held, and/or marketed by the Company, such product is being
manufactured, held and distributed in substantial compliance with all applicable
requirements under the FDCA and the CSA including, but not limited to, those
relating to investigational use, premarket clearance, good manufacturing
practices, labeling, advertising, record keeping, filing of reports, and
security.



<PAGE>
                                      -14-


     (c) The Company will promptly provide Parent with copies of any document
that is issued, prepared, or otherwise becomes available from the date of this
Agreement until the Effective Time which bears on the regulatory status under
the FDCA or the CSA of the Company or any product of the Company, including, but
not limited to, any deficiency letter, warning letter, non-approvable
letter/order, and withdrawal letter/order, except for documents reflecting such
matters which, individually and in the aggregate, would not have a Material
Adverse Effect.

     SECTION 3.07. SEC Filings; Financial Statements.

     (a) The Company has filed all periodic reports and documents required under
the Exchange Act to be filed by it with the Securities and Exchange Commission
(the "SEC") since November 10, 1995, including all exhibits filed in connection
therewith (collectively, the "Company SEC Reports"). The Company SEC Reports (i)
were prepared in all material respects in accordance with the requirements of
the Exchange Act and the rules and regulations thereunder and (ii) did not at
the time they were filed contain any untrue statement of a material fact or omit
to state a material fact required to be stated therein or necessary in order to
make the statements made therein, in the light of the circumstances under which
they were made, not misleading. The Company will deliver to the Parent as soon
as they become available true and complete copies of any Company SEC Reports
filed subsequent to the date hereof and prior to the Effective Time.

     (b) The Company will deliver to Parent as soon as they become available
true and complete copies of any report, registration statement or statement
mailed by it to its securityholders generally (the "Mailings") subsequent to the
date hereof and prior to the Effective Time. As of their respective dates, such
Mailings (excluding any information therein provided by Parent or Merger Sub, as
to which the Company makes no representation) will not contain any untrue
statement of a material fact or omit to state a material fact required to be
stated therein or necessary to make the statements therein, in light of the
circumstances under which they are made, not misleading and will comply in all
material respects with all applicable requirements of law.

     (c) Each of the financial statements (including, in each case, any notes
and schedules thereto) contained in the Company SEC Reports complied, and in the
Mailings will comply, as to form with the applicable accounting requirements and


<PAGE>
                                      -15-


rules and regulations of the United States Securities and Exchange Commission
("SEC") and was prepared in accordance with United States generally accepted
accounting principles applied on a consistent basis throughout the periods
indicated (except as may be indicated in the notes thereto), and each fairly
presented in all material respects the consolidated financial position, results
of operations and cash flows of the Company and the consolidated Subsidiaries as
at the respective dates thereof and for the respective periods indicated therein
in accordance with United States generally accepted accounting principles
(subject, in the case of unaudited statements, to normal and recurring year-end
adjustments).

     (d) Except as and to the extent set forth on the balance sheet of the
Company as of September 30, 1997, including the notes thereto (the "Company 1997
Balance Sheet"), the Company has no material liability or obligation of any
nature (whether accrued, absolute, contingent or otherwise) that would be
required to be reflected on a balance sheet, or in the notes thereto, prepared
in accordance with United States generally accepted accounting principles,
except for liabilities and obligations (i) disclosed in any Company SEC Report
and Mailing filed since September 30, 1997 and prior to the date of this
Agreement, (ii) incurred since September 30, 1997 in the ordinary course of
business or (iii) incurred pursuant to this Agreement.

     (e) The Company has heretofore furnished to Parent complete and correct
copies of all material amendments and modifications that have not been filed by
the Company with the SEC to all agreements, documents and other instruments that
previously had been filed by the Company with the SEC and are currently in
effect.

     SECTION 3.08. Absence of Certain Changes or Events. Since December 31,
1996, except as disclosed in any Company SEC Report filed since December 31,
1996 and prior to the date hereof, there has not been any event or events
having, or reasonably likely to have, individually or in the aggregate, a
Company Material Adverse Effect.

     SECTION 3.09. Absence of Litigation. Except as disclosed in the Company SEC
Reports or in Section 3.09 of the Company Disclosure Schedule, there is no
claim, action, proceeding or investigation pending or, to the Company's
Knowledge, threatened against the Company, or any property or asset of the
Company, before any court, arbitrator or Governmental Authority, which,
individually or when aggregated 



<PAGE>
                                      -16-


with other claims, actions, proceedings or investigations or product liability
claims, actions, proceedings or investigations which are reasonably likely to
result from facts and circumstances that have given rise to such a claim,
action, proceeding or investigation, would have a Company Material Adverse
Effect. As of the date hereof, neither the Company nor any property or asset of
the Company is subject to any order, writ, judgment, injunction, decree,
determination or award having, individually or in the aggregate, a Company
Material Adverse Effect.

     SECTION 3.10. Pension and Other Benefit Plans.

     (a) Section 3.10 of the Company Disclosure Schedule sets forth a complete
list of all Employee/Benefit Plans.

     (b) Except as disclosed in Section 3.10 of the Company Disclosure Schedule,
there are no "employee pension benefit plans" as defined in Section 3(2) of the
Employee Retirement Income Security Act of 1974, as amended ("ERISA") ("Pension
Benefit Plans"), "welfare benefit plans" as defined in Section 3(1) of ERISA
("Welfare Plans"), or stock bonus, stock option, restricted stock, stock
appreciation right, stock purchase, bonus, incentive, deferred compensation,
severance, or vacation plans, or any other employee benefit plan, program,
policy or arrangement, covering employees (or former employees) employed in the
United States, maintained or contributed to by the Company or any of its ERISA
Affiliates (as hereinafter defined), or to which the Company or any of its ERISA
Affiliates contributes or is obligated to make payments thereunder or otherwise
may have any liability (collectively, the "Employee Benefit Plans"). For
purposes of this Agreement, "ERISA Affiliate" shall mean any person (as defined
in Section 3(9) of ERISA) that is or has been a member of any group of persons
described in Section 414(b), (c), (m) or (o) of the Code including the Company.

     (c) The Company and each of the Pension Benefit Plans and Welfare Plans,
are in compliance with the applicable provisions of ERISA, the Code and other
applicable laws except where the failure to comply would not, individually and
in the aggregate, have a Material Adverse Effect.

     (d) All contributions to, and payments from, the Pension Benefit Plans
which are required to have been made in accordance with the Pension Benefit
Plans have been timely made except where the failure to make such contributions
or payments on a timely basis would not, individually and in the aggregate,


<PAGE>
                                      -17-


either impair the Company's ability to consummate the Merger and the other
transactions contemplated hereby or have a Material Adverse Effect.

     (e) Any Pension Benefit Plans intended to qualify under Section 401 of the
Code have been determined by the Internal Revenue Service ("IRS") to be so
qualified and no event has occurred and no condition exists with respect to the
form or operation of such Pension Benefit Plans which would cause the loss of
such qualification or exemption or the imposition of any material liability,
penalty or tax under ERISA or the Code.

     (f) There are (i) no investigations pending by any governmental entity
involving the Pension Benefit Plans or Welfare Plans, and (ii) no pending or
threatened claims (other than routine claims for benefits), suits or proceedings
against any Pension Benefit or Welfare Plan, against the assets of any of the
trusts under any Pension Benefit or Welfare Plan or against any fiduciary of any
Pension Benefit or Welfare Plan with respect to the operation of such plan or
asserting any rights or claims to benefits under any Pension Benefit Plan or
against the assets of any trust under such plan, except for those which would
not, individually and in the aggregate, give rise to any liability which would
have a Material Adverse Effect, nor, to the best of the Company's knowledge, are
there any facts which would give rise to any liability except for those which
would not, individually or in the aggregate, either impair the Company's ability
to consummate the Merger and the other transactions contemplated hereby or have
a Material Adverse Effect in the event of any such investigation, claim, suit or
proceeding.

     (g) None of the Company or any employee of the Company, nor any trustee,
administrator, other fiduciary or any other "party in interest" or "disqualified
person" with respect to the Pension Benefit Plans or Welfare Plans, has engaged
in a "prohibited transaction" (as such term is defined in Section 4975 of the
Code or Section 406 of ERISA) which could result in a tax or penalty on the
Company under Section 4975 of the Code or Section 502(i) of ERISA, except any
such event which would not, individually and in the aggregate, either impair the
Company's ability to consummate the Merger and the other transactions
contemplated hereby or have a Material Adverse Effect.

     (h) None of the Company or any of its ERISA Affiliates maintains or
contributes to, nor have they ever maintained 



<PAGE>
                                      -18-


or contributed to, any pension plan subject to Title IV of ERISA or Sections 412
of the Code or 302 of ERISA.

     (i) Neither the Company nor any ERISA Affiliate has incurred any material
liability under Title IV of ERISA.

     (j) None of the Company or any of its ERISA Affiliates has any material
liability (including any contingent liability under Section 4204 of ERISA) with
respect to any multiemployer plan, within the meaning of Section 3(37) of ERISA,
covering employees (or former employees) employed in the United States.

     (k) With respect to each of the Employee Benefit Plans, true, correct and
complete copies of the following documents have been made available to Parent:
(i) the plan document and any related trust agreement, including amendments
thereto, (ii) any current summary plan descriptions and other material
communications to participants relating to the Employee Benefit Plans, (iii) the
most recent Forms 5500, if applicable, and (iv) the most recent IRS
determination letter, if applicable.

     (l) None of the Welfare Plans maintained by the Company provides for
continuing benefits or coverage for any participant or any beneficiary of a
participant following termination of employment, except as may be required under
the Consolidated Omnibus Budget Reconciliation Act of 1985, as amended
("COBRA"), or except at the expense of the participant or the participant's
beneficiary. The Company has complied with the notice and continuation
requirements of Section 4980B of the Code, COBRA, Part 6 of Subtitle B of Title
I of ERISA and the regulations thereunder except where the failure to comply
would not, individually and in the aggregate, either impair the Company's
ability to consummate the Merger and the other transactions contemplated hereby
or have a Material Adverse Effect.

     (m) No liability under any Pension Benefit or Welfare Plan has been funded
nor has any such obligation been satisfied with the purchase of a contract from
an insurance company as to which the Company has received notice that such
insurance company is in rehabilitation or a comparable proceeding.

     (n) Except as set forth in Section 3.10 of the Company Disclosure Schedule,
the consummation of the transactions contemplated by this Agreement will not
result in an increase in the amount of compensation or benefits or accelerate
the 



<PAGE>
                                      -19-


vesting or timing of payment of any benefits or compensation payable to or in
respect of any employee of the Company.

     (o) The Company has disclosed to Parent in Section 3.10 of the Company
Disclosure Schedule each Foreign Plan (as hereinafter defined) to the extent the
benefits provided thereunder are not mandated by the laws of the applicable
foreign jurisdiction. The Company and each of the Foreign Plans are in
compliance with applicable laws and all required contributions have been made to
the Foreign Plans, except where the failure to comply or make contributions
would not, individually and in the aggregate, either impair the Company's
ability to consummate the Merger and the other transactions contemplated hereby
or have a Material Adverse Effect. Each of the Foreign Plans that is a funded
defined benefit plan has a fair market value of plan assets that is greater than
the plan's liabilities, as determined in accordance with applicable laws. For
purposes hereof, the term "Foreign Plan" shall mean any plan, program, policy,
arrangement or agreement maintained or contributed to by, or entered into with,
the Company with respect to employees (or former employees) employed outside the
United States.

     SECTION 3.11. Intellectual Property Rights. To the best of the Company's
knowledge, the Company owns or has the right to use all Intellectual Property
Rights (as defined below in this Section 3.11) necessary to the conduct of its
businesses. Section 3.11 of the Company Disclosure Schedule contains a list of
all material patents, trade names, trademarks and service marks, and
applications for the foregoing owned or possessed by the Company. No material
rights or licenses to use Intellectual Property Rights have been granted or
acquired by the Company except those listed in Section 3.11 of the Company
Disclosure Schedule. Except as disclosed in Section 3.11 of the Company
Disclosure Schedule, the Company has received no notice of any claims or
assertions made by others that the Company has infringed any material
Intellectual Property Rights of others by the sale of products or any other
activity in the preceding five year period. Except as set forth in Section 3.11
of the Company Disclosure Schedule, the Company has no knowledge of any
infringement of Intellectual Property Rights of the Company by others which
would result in a Company Material Adverse Effect. Except as set forth in
Section 3.11 of the Company Disclosure Schedule all issued patents, registered
trademarks, and service marks, owned by the Company are recorded on the public
record in the name of the Company. True and complete copies of all material
listed in Section 3.11 of the Company Disclosure Schedule have been made
available to Parent.



<PAGE>
                                      -20-


     "Intellectual Property Rights" shall mean and include rights relating to
the Company's patents, trademarks, service marks, trade names, registered
copyrights, and all currently pending applications for any thereof.

     SECTION 3.12. Tax Matters. Except for those matters which individually and
in the aggregate would not have a Material Adverse Effect, (i) except as set
forth in Section 3.12 of the Company Disclosure Schedule, the Company has
prepared and timely filed or will timely file with the appropriate governmental
agencies all franchise, income and all other Tax (as hereinafter defined)
returns, information statements and reports (Tax returns and reports are
hereinafter collectively referred to as "Tax Returns") required to be filed for
any period on or before the Effective Time, taking into account any extension of
time to file granted to or obtained on behalf of the Company (copies of which
for the past three fiscal years have been provided to Parent); (ii) all Taxes of
the Company in respect of any taxable period (or portion thereof) ending prior
to or on the Effective Time have been paid in full to the proper authorities or
fully accrued for with respect to fiscal periods for which there are publicly
available financial statements and otherwise on the books of the Company, other
than such Taxes as are being contested in good faith by appropriate proceedings
and are adequately reserved for in accordance with generally accepted accounting
principles; (iii) all deficiencies resulting from Tax examinations of federal,
state, local and foreign income, sales and franchise and all other Tax Returns
filed by the Company have either been paid or adequately reserved for in
accordance with generally accepted accounting principles; (iv) no deficiency has
been asserted or assessed against the Company and is pending, and no examination
of the Company is pending or threatened for any material amount of Tax by any
taxing authority; (v) no extension of the period for assessment or collection of
any Tax is currently in effect and no extension of time within which to file any
Tax Return has been requested, which Tax Return has not since been filed; (vi)
no Tax liens have been filed with respect to any Taxes, except for property
taxes which have accrued but are not yet due and payable; (vii) the Company has
not agreed, and is not required, to make any adjustment by reason of a change in
their accounting methods that would affect the taxable income or deductions of
the Company for any period ending after the Effective Time; (viii) the Company
has made timely payments of the Taxes required to be deducted and withheld from
the wages paid to their employees and from amounts paid to any other third
parties; (ix) there are no Tax sharing agreements or 



<PAGE>
                                      -21-


arrangements under which the Company will have any obligation or liability on or
after the Effective Time; (x) the Company has the net operating loss
carryforwards set forth in Section 3.12 of the Company Disclosure Schedule; (xi)
the Company has no overall foreign losses as defined in Section 904(f)(2) of the
Code; (xii) the Company has no unused foreign tax credits; (xiii) there are no
transfer pricing agreements made by the Company with any taxation authority;
(xiv) except as set forth in Section 3.12 of the Company Disclosure Schedule no
assets of the Company are held in an arrangement for which partnership Tax
Returns are being filed and the Company is not a partner in any partnership;
(xv) except as set forth in Section 3.12 of the Company Disclosure Schedule, the
Company does not own any interest in any "controlled foreign corporation"
(within the meaning of Section 957 of the Code), "passive foreign investment
company" (within the meaning of Section 1296 of the Code) or other entity the
income of which is required to be included in the income of the Company whether
or not distributed; (xvi) the Company has not made an election under Section
341(f) of the Code; and (xvii) except as set forth in Section 3.12 of the
Company Disclosure Schedule, the Company is not obligated to make any payments
or provide any other benefits that would constitute excess parachute payments
within the meaning of Section 280G of the Code.

     "Tax" or "Taxes" means (i) all federal, state, local or foreign taxes,
charges, fees, imposts, levies or other assessments, including, without
limitation, all net income, alternative minimum, gross receipts, capital, sales,
use, ad valorem, value added, transfer, franchise, profits, inventory, capital
stock, license, withholding, payroll, employment, social security, unemployment,
excise, severance, stamp, occupation, property and estimated taxes, customs
duties, fees, assessments and charges of any kind whatsoever, (ii) all interest,
penalties, fines, additions to tax or other additional amounts imposed by any
taxing authority in connection with any item described in clause (i), and (iii)
all transferee, successor, joint and several or contractual liability
(including, without limitation, liability pursuant to United States Treasury
Regulation ("Treas. Reg.") ss. 1.1502-6 (or any comparable state, local or
foreign provisions)) in respect of any items described in clause (i) or (ii)
above.

     SECTION 3.13. Environmental Matters.

     (a) To the best of the Company's Knowledge, the Company possesses all
Environmental Permits, except as disclosed on Section 3.13 of the Company
Disclosure Schedule, required 



<PAGE>
                                      -22-


under applicable Environmental Laws to conduct its current business, and is, and
to the Company's knowledge has at all times been, in compliance with the terms
and conditions of such Environmental Permits, except where such failures to
possess or comply, individually and in the aggregate, would not have a Company
Material Adverse Effect, nor has the Company reason to believe that any
Environmental Permits possessed by the Company will be revoked, suspended, or
will not be renewed.

     (b) To the best of the Company's Knowledge, the execution and delivery of
this Agreement and the consummation by the Company of the Merger and other
transactions contemplated hereby and the exercise by the Parent and the Merger
Sub of rights to own and operate the businesses of the Company substantially as
presently conducted will not affect the validity or require the transfer of any
Environmental Permits held by the Company, and will not require any
notification, disclosure, registration, reporting, filing, investigation, or
remediation under any Environmental Law.

     (c) To the best of the Company's Knowledge, the Company is in compliance,
and within the period of all applicable statutes of limitation, has complied,
with all applicable Environmental Laws except where the failure to comply,
individually and in the aggregate, would not have a Company Material Adverse
Effect; and has not received notice of any liability under any Environmental
Law.

     (d) To the best of the Company's Knowledge, there is no civil, criminal, or
administrative action, suit, demand, claim, hearing, notice of violation,
investigation, notice or demand letter, or request for information pending or,
to the knowledge of the Company, threatened under any Environmental Law (a)
against the Company, or (b) against any person or entity, including but not
limited to any Contractor (as hereinafter defined), in connection with which
liability could reasonably be imputed or attributed by law or contract to the
Company.

     (e) To the best of the Company's Knowledge, no property or facility
presently or formerly owned, operated, or leased by the Company, or by any
respective predecessor in interest, is listed or proposed for listing on the
National Priorities List or the Comprehensive Environmental Response,
Compensation and Liability Information System, both promulgated under the
Comprehensive Environmental Response, Compensation and Liability Act, as amended
("CERCLA"), or on any comparable list established under any Environmental Law,
nor has the Company received any notification of potential or actual liability




<PAGE>
                                      -23-


or any request for information under CERCLA or any comparable foreign, state, or
local law.

     (f) To the best of the Company's Knowledge, there has been no disposal,
spill, discharge, or release of any Hazardous Material generated, used, owned,
stored, or controlled by the Company or respective predecessors in interest, on,
at, or under any property presently or formerly owned, leased, or operated by
the Company, any predecessor in interest, or any Contractor, and there are no
Hazardous Materials located in, at, on, or under, or in the vicinity of, any
such facility or property, or at any other location, in either case that could
reasonably be expected to require investigation, removal, remedial, or
corrective action by the Company or that would reasonably likely result in
liability of, or costs in excess of $100,000, either individually or in the
aggregate, to the Company under any Environmental Law.

     (g) To the best of the Company's Knowledge, there has not been any
underground or aboveground storage tank or other underground storage receptacle
or related piping, or any impoundment or other disposal area containing
Hazardous Materials located on any facility or property owned, leased or
operated by the Company or its predecessors in interest during the period of
such ownership, lease or operation, and no asbestos or polychlorinated biphenyls
have been used or disposed of, or have been located at, on, or under any such
facility or property during the period of such ownership lease or operation.

     (h) To the best of the Company's Knowledge, no lien has been recorded
against any properties, assets or facilities owned, leased or operated by the
Company under any Environmental Law.

     (i) To the best of the Company's Knowledge, a reasonable investigation
having been made, the Company has made available to Parent, Merger Sub and their
authorized representatives all records and files, including, but not limited to,
all assessments, reports, studies, audits, analyses, tests and data in
possession of the Company concerning the existence of Hazardous Materials at
facilities or properties currently or formerly owned, operated, or leased by the
Company or any former subsidiary or predecessor in interest, or concerning
compliance by the Company with, or liability under, any Environmental Law.

     For purposes of this Agreement:



<PAGE>
                                      -24-



          (i) "Contractor" shall mean any person or entity, including but not
     limited to partners, licensors, and licensees, with which the Company
     formerly or presently has any agreement or arrangement under which such
     person or entity has or had physical possession of, and was or is obligated
     to develop, test, process, manufacture or produce any of their component
     ingredients owned by the Company.

          (ii) "Environmental Law" shall mean CERCLA, the Resource Conservation
     and Recovery Act of 1976, as amended, and any other applicable federal,
     state, local, or foreign statute, rule, regulation, order, judgment,
     directive, decree or common law as now or previously in effect and
     regulating, relating to, or imposing liability or standards of conduct
     concerning air emissions, water discharges, noise emissions, the release or
     threatened release or discharge of any Hazardous Material into the
     environment, the generation, handling, treatment, storage, transport or
     disposal of any Hazardous Material, or otherwise concerning pollution or
     the protection of the outdoor or indoor environment, employee health or
     safety, the experimental use of animals, or the disposal of animal
     carcasses.

          (iii) "Environmental Permit" shall mean any permit, license, approval,
     consent, or other authorization by a federal, state, local, or foreign
     government or regulatory entity pursuant to any Environmental Law.

          (iv) "Hazardous Material" shall mean any pollutant, contaminant, or
     hazardous, toxic, medical, biohazardous, infectious or dangerous waste,
     substance, constituent or material, defined or regulated as such in, or for
     purposes of, any Environmental Law, including, without limitation, any
     asbestos, any petroleum, oil (including crude oil or any fraction thereof),
     any radioactive substance, any polychlorinated biphenyls, any animal
     carcass, any toxin, chemical, virus, infectious disease or disease-causing
     agent, and any other substance that can give rise to liability under any
     Environmental Law.

     SECTION 3.14. Tax Treatment; Officer's Certificate as to Tax Matters.
Neither the Company nor, to the Company's Knowledge, any of its affiliates has
taken, agreed to take, or will take any action that would prevent the Merger
from constituting a transaction qualifying under Section 368(a) of the Code or
that would prevent an exchange of Company Common 



<PAGE>
                                      -25-


Stock for Parent ADSs pursuant to the Merger from qualifying as an exchange
described in Section 354 of the Code (except with respect to any cash received
in lieu of a fractional share) to which Section 367(a)(1) of the Code does not
apply. Neither the Company nor, to the Company's Knowledge, any of its
affiliates or agents is aware of any agreement, plan or other circumstance that
would prevent the Merger from qualifying under Section 368(a) of the Code or
that would prevent an exchange of Company Common Stock for Parent ADSs pursuant
to the Merger from qualifying as an exchange described in Section 354 of the
Code (except with respect to any cash received in lieu of a fractional share) to
which Section 367(a)(1) of the Code does not apply, and to the Company's
Knowledge, the Merger and each such exchange will so qualify. As of the date
hereof, the Company knows of no reason why it will be unable to deliver to
Greenberg, Traurig, Hoffman, Lipoff, Rosen & Quentel, P.A. and to Cahill Gordon
& Reindel at the Closing representation letters with respect to the Company in
form and substance sufficient to enable such counsel to render the opinions
required by Sections 7.02(b) and 7.03(b).

     SECTION 3.15. Insurance. Section 3.15 of the Company Disclosure Schedule
lists all insurance policies in force on the date hereof covering the
businesses, properties and assets of the Company and its Subsidiaries, the
premiums and coverages of such policies and all claims against such policies.
All such policies are currently in effect and true and complete copies of all
such policies have been made available to Parent. The Company has not received
notice of the cancellation of any of such insurance in effect on the date of
this Agreement.

     SECTION 3.16. Stockholder Vote Required. The affirmative vote of the
holders of a majority of the outstanding shares of Company Common Stock is the
only vote of the holders of any class or series of capital stock of the Company
necessary to approve the Merger.

     SECTION 3.17. Opinion of Financial Advisor. The Company has received the
opinion of Vector Securities International, Inc. (the "Company Financial
Advisor"), to the effect that, as of the date hereof, the Merger Consideration
is fair to the Company's stockholders from a financial point of view.

     SECTION 3.18. Brokers. No broker, finder or investment banker (other than
the Company Financial Advisor) is entitled to any brokerage, finder's or other
fee or commission in connection with the Merger based upon arrangements made by


<PAGE>
                                      -26-


or on behalf of the Company. The Company has heretofore furnished to Parent a
complete and correct copy of all agreements between the Company and the Company
Financial Advisor pursuant to which such firm would be entitled to any payment
relating to the Merger.

     SECTION 3.19. State Takeover Statutes. The Company's Board of Directors
approved the Merger and this Agreement and all agreements related thereto, and
such approval is sufficient to render inapplicable to the Merger and this
Agreement, and the transactions contemplated by this Agreement and all related
agreements, the provisions of Sections 607.0901, 607.0902 and 607.1302 of the
Florida Law to the extent, if any, any such sections, or any other State of
Florida antitakeover statute or regulation are applicable to the Merger and this
Agreement and the transactions contemplated by this Agreement and all related
agreements.

     SECTION 3.20. Labor Matters; Employment and Labor Contracts. (a) The
Company is not a party to any union contract or other collective bargaining
agreement. The Company is in compliance with all applicable laws respecting
employment and employment practices, terms and conditions of employment and
wages and hours, except for those failures to comply which, individually and in
the aggregate, would not have a Material Adverse Effect. There is no labor
strike, slowdown or stoppage pending (or any labor strike or stoppage
threatened) against or affecting the Company. No petition for certification has
been filed and is pending before the National Labor Relations Board with respect
to any employees of the Company.

     (b) Except as entered into in the ordinary course of business or as set
forth in Section 3.20 of the Company Disclosure Schedule, the Company is not a
party to any employment, management services, consultation, indemnification or
other contract or agreement with any past or present officer, director or
employee or, to the best of the Company's Knowledge, any entity affiliated with
any past or present officer, director or employee. True and correct copies of
all agreements referred to in Section 3.20 of the Company Disclosure Schedule
have been previously delivered to Parent.

     SECTION 3.21. Board Recommendation. The Board of Directors of the Company
has, by a unanimous vote at a meeting of such Board duly held on December 11,
1997, approved and adopted this Agreement, the Merger and the other transactions
contemplated hereby, and determined that the Agreement, the Merger and the other
transactions contemplated hereby, taken 



<PAGE>
                                      -27-



together, are fair to and in the best interest of the stockholders of the
Company, and resolved to recommend that the holders of shares of Company Common
Stock approve and adopt this Agreement, the Merger and the other transactions
contemplated hereby.


                                   ARTICLE IV

                    REPRESENTATIONS AND WARRANTIES OF PARENT
                                 AND MERGER SUB


     Except as disclosed in a separate disclosure schedule referring to the
Sections contained in this Agreement, which has been delivered by the Company to
Parent prior to the execution of this Agreement (the "Parent Disclosure
Schedule"), Parent and Merger Sub hereby, jointly and severally, represent and
warrant to the Company that:

     SECTION 4.01. Organization and Qualification; Subsidiaries. Each of Parent
and its subsidiaries (collectively, the "Parent Subsidiaries") is a corporation
duly organized, validly existing and in good standing under the laws of the
jurisdiction of its incorporation and has the requisite power and authority and
all necessary governmental approvals to own, lease and operate its properties
and to carry on its business as it is now being conducted. Each of Parent and
Parent Subsidiaries is duly qualified or licensed as a foreign corporation to do
business, and is in good standing, in each jurisdiction where the character of
the properties owned, leased or operated by it or the nature of its business
makes such qualification or licensing necessary, except for such failures to be
so qualified or licensed and in good standing that, individually or in the
aggregate, would not have a Parent Material Adverse Effect. The term "Parent
Material Adverse Effect" means any change in, or effect on, Parent, when taken
as a consolidated whole, which is, or could reasonably be expected in the future
to be, materially adverse to the operations, assets or liabilities or earnings
or results of operations of Parent and Parent Subsidiaries taken as a whole.
Parent owns directly all of the outstanding capital stock of Merger Sub.

     SECTION 4.02. Charter Documents and By-laws. Parent has heretofore
furnished to the Company a complete and correct copy of its Memorandum and
Articles of Association (or other applicable charter document) and Bylaws, each
as amended to 



<PAGE>
                                      -28-


date, of Parent and Merger Sub. Such charter documents are in full force and
effect. Neither Parent nor Merger Sub is in violation of any provision of its
respective charter documents.

     SECTION 4.03. Parent ADSs to Be Issued in the Merger. The issuance of the
Parent ADSs, each representing one Parent Ordinary Share, pursuant to the Merger
will be duly authorized, validly issued, fully paid and not subject to calls for
additional payments of any kind, and not subject to preemptive rights created by
statute, Parent's Memorandum and Articles of Association or By-laws or any
agreement to which Parent is a party or by which Parent is bound and will, when
issued, be registered under the Securities Act and the Exchange Act and
registered or exempt from registration under applicable Blue Sky Laws.

     SECTION 4.04. Authority Relative to This Agreement. Each of Parent and
Merger Sub has all necessary corporate power and authority to execute and
deliver this Agreement, to perform its obligations hereunder and to consummate
the Merger. The execution and delivery of this Agreement by Parent and Merger
Sub and the consummation by Parent and Merger Sub of the Merger have been duly
and validly authorized by all necessary corporate action and no other corporate
proceedings on the part of Parent or Merger Sub are necessary to authorize this
Agreement or to consummate the Merger (other than, with respect to the Merger,
the filing and recordation of appropriate merger documents as required by
Florida Law and Delaware Law). This Agreement has been duly and validly executed
and delivered by Parent and Merger Sub and, assuming the due authorization,
execution and delivery by the Company, constitutes a legal, valid and binding
obligation of each of Parent and Merger Sub enforceable against each of Parent
and Merger Sub in accordance with its terms, subject to bankruptcy, insolvency,
fraudulent transfer, reorganization, moratorium and similar laws of general
applicability relating to or affecting creditors' rights and to general equity
principles.

     SECTION 4.05. No Conflict; Required Filings and Consents.

     (a) The execution and delivery of this Agreement by Parent and Merger Sub
do not, and the performance of this Agreement by Parent and Merger Sub will not,
(i) conflict with or violate the charter documents, By-laws or other
organizational documents of Parent or Merger Sub, (ii) conflict with or violate
any Law applicable to Parent or Merger Sub or by which any property or asset of
Parent or Merger Sub is bound or af-



<PAGE>
                                      -29-


fected, except for such conflicts or violations which would not, individually or
in the aggregate, have a Parent Material Adverse Effect, (iii) prevent or
materially delay the consummation of the Merger or (iv) result in any breach of
or constitute a default (or an event which with notice or lapse of time or both
would become a default) under any note, bond, mortgage, indenture, contract,
agreement, lease, license, permit, franchise or other instrument or obligation
to which Parent or Merger Sub is a party or by which Parent or Merger Sub or any
property or asset of either of them is bound or affected, except for any such
breaches or defaults which, individually or in the aggregate, would not have a
Parent Material Adverse Effect.

     (b) No filing or registration with, or authorization, consent or approval
of, or notification to any governmental entity is required by Parent or Merger
Sub in connection with the execution and delivery of this Agreement or the
consummation by Parent and Merger Sub of the Merger and the other transactions
contemplated hereby, except (i) in connection with the applicable requirements
of the HSR Act, (ii) in connection with the applicable requirements of the
Mergers, Take-overs and Monopolies (Control) Act, 1978 (as amended) of Ireland
(the "Irish Mergers Act"), (iii) in connection with the provisions of the
Securities Act and Exchange Act, (iv) the filing of appropriate merger documents
as required by Florida Law and Delaware Law, (v) the listing on the New York
Stock Exchange ("NYSE") of the Parent ADSs to be issued in connection with the
Merger, (vi) the listing on the respective official lists of the Irish Stock
Exchange and the London Stock Exchange of Parent Ordinary Shares to be
represented by Parent ADSs constituting the Merger Consideration, (vii) such
consents, approvals, orders, authorizations, registrations, declarations and
filings as may be required under the corporation, takeover or blue sky laws of
various states, (viii) such authorizations, orders, consents, licenses,
confirmations, clearances, permissions and approvals as may be required in any
foreign jurisdiction for the purposes of applicable anti-trust, competition,
takeover or similar legislation, and (ix) such other consents, orders,
authorizations, registrations, declarations and filings the failure of which to
be obtained or made, individually and in the aggregate, would not, either impair
the ability of Parent or Merger Sub to consummate the Merger and the other
transactions contemplated hereby or have a Parent Material Adverse Effect.

     SECTION 4.06. SEC Filings; Financial Statements.



<PAGE>
                                      -30-


     (a) Parent has filed all periodic reports and documents required under the
Exchange Act to be filed by it with the SEC since January 1, 1995, including all
exhibits filed in connection therewith (collectively, but excluding filings
relating solely to press releases (other than earnings releases), the "Parent
SEC Reports"). The Parent SEC Reports (i) were prepared in accordance with the
requirements of the Exchange Act and the rules and regulations thereunder, and
(ii) did not at the time they were filed contain any untrue statement of a
material fact or omit to state a material fact required to be stated therein or
necessary in order to make the statements made therein, in the light of the
circumstances under which they were made, not misleading. Parent will deliver to
the Company as soon as they become available true and complete copies of any
Parent SEC Reports filed subsequent to the date hereof and prior to the
Effective Time.

     (b) The audited consolidated financial statements and unaudited
consolidated interim financial statements of Parent and Parent Subsidiaries
included or incorporated by reference in the Parent SEC Reports were prepared in
accordance with generally accepted accounting principles in the United States,
in each case applied on a consistent basis throughout the periods involved and
fairly present the consolidated financial position of Parent and Parent
Subsidiaries as of the dates thereof and the consolidated results of operations
and consolidated cash flow for the periods then ended (subject, in the case of
any unaudited interim financial statements, to normal year-end adjustments and
to the extent they may not include footnotes or may be condensed or summary
statements) and such audited consolidated financial statements have been
certified as such (without exception) by Parent's independent chartered
accountants.

     SECTION 4.07. Absence of Certain Changes or Events. Since December 31,
1996, except as disclosed in any Parent SEC Report filed since December 31, 1996
and prior to the date hereof, there has not been any event or events having, or
reasonably likely to have, individually or in the aggregate, a Parent Material
Adverse Effect.

     SECTION 4.08. Brokers. Except for Goldman Sachs International, no broker,
finder or investment banker is entitled to any brokerage, finder's or other fee
or commission in connection with the Merger based upon arrangements made by or
on behalf of Parent, any Parent Subsidiary or Merger Sub.



<PAGE>
                                      -31-


     SECTION 4.09. Capitalization. The authorized capital stock of Parent
consists of 100,000,000 Parent Ordinary Shares, 1,000 executive shares, par
value 1 Irish pound per share ("Parent Executive Shares") and 25,000 `B'
executive shares, par value 4 Irish pence per share ("Parent `B' Executive
Shares"). As of June 30, 1997, there were 99,463,709 Parent Ordinary Shares
issued and outstanding, no Parent Ordinary Shares held in Parent's treasury,
1,000 Parent Executive Shares outstanding and 21,375 Parent `B' Executive Shares
outstanding. As of such date there were 11,658,203 Parent Ordinary Shares
reserved for issuance upon the exercise of outstanding options ("Outstanding
Options"), 4,288,322 Parent Ordinary Shares reserved for issuance upon the
exchange of the Liquid Yield Option Notes (the "LYONs") issued by Elan
International Finance Ltd., a wholly-owned subsidiary of Parent, and guaranteed
by Parent and 13,239,178 Parent Ordinary Shares reserved for issuance upon the
exercise of outstanding warrants (the "Warrants"). Except for the LYONs, the
Warrants and the Outstanding Options, there were not as of June 30, 1997 any
existing options, warrants, calls, subscriptions, or other rights or other
agreements or commitments obligating Parent to issue, transfer or sell any
shares of its capital stock or any other securities convertible into or
evidencing the right to subscribe for any such shares. All issued and
outstanding Parent Ordinary Shares are duly authorized, validly issued and,
except for the 42,553 Elan Ordinary Shares represented by ADRs evidencing Parent
ADSs issued in the name of Sylvan Limited on April 13, 1995, fully paid, and not
subject to calls for additional payments of any kind. On October 31, 1997, the
LYONs were called for redemption and prior to the redemption date of November
30, 1997 substantially all of the outstanding LYONs were exchanged for Parent
ADRs. On November 12, 1997, Athena Neurosciences, Inc., a wholly-owned
subsidiary of Parent, issued $325,000,000 principal amount of 4.75% Exchangeable
Notes due November 15, 2004, which are guaranteed as to payment of principal and
interest by Parent and are exchangeable into Parent ADSs at an exchange rate of
14.0758 Parent ADSs per $1,000 principal amount of such notes.

     SECTION 4.10. Litigation. There is no (i) claim, action, suit or proceeding
pending or, to the best knowledge of the Parent, threatened against or relating
to the a Parent or any of its Parent Subsidiaries before any court or
governmental or regulatory authority or body or arbitration tribunal, or (ii)
outstanding judgment, order, writ, injunction or decree, or application, request
or motion therefor, of any court, governmental agency or arbitration tribunal in
a proceeding to which Parent, any Parent Subsidiary or any of their respective


<PAGE>
                                      -32-


assets was or is a party except, in the case of clauses (i) and (ii) above, such
as would not, individually and in the aggregate, either impair Parent's ability
to consummate the Merger or the other transactions contemplated hereby or have a
Parent Material Adverse Effect.

     SECTION 4.11. No Shareholder Vote Required. The vote by any holders of any
class or series of capital stock of the Parent is not required to approve the
Merger.

     SECTION 4.12. Tax Treatment; Officer's Certificate as to Tax Matters.
Neither Parent nor, to Parent's knowledge, any of its affiliates has taken,
agreed to take, or will take any action that would prevent the Merger from
constituting a transaction qualifying under Section 368(a) of the Code or that
would prevent an exchange of Company Common Stock for Parent ADSs pursuant to
the Merger from qualifying as an exchange described in Section 354 of the Code
(except with respect to any cash received in lieu of a fractional share) to
which Section 367(a)(1) of the Code does not apply. Neither Parent nor, to
Parent's Knowledge, any of its affiliates or agents is aware of any agreement,
plan or other circumstances that would prevent the Merger from qualifying under
Section 368(a) of the Code or that would prevent an exchange of Company Common
Stock for Parent ADSs pursuant to the Merger from qualifying as an exchange
described in Section 354 of the Code (except with respect to any cash received
in lieu of a fractional share) to which Section 367(a)(1) of the Code does not
apply, and to Parent's Knowledge, the Merger and each such exchange will so
qualify; provided that (i) Company complies with the reporting requirements
contained in Treasury Regulation Section 1.367(a)-3(c)(6), (ii) the Company
stockholder owns (including beneficial, indirect and construction ownership)
less than five percent of the total voting power and total value of Parent's
outstanding stock immediately after the Merger, and (iii) the Company
stockholder complies with the notice requirements of Section 6038B of the Code.
As of the date hereof, Parent knows of no reason why it will be unable to
deliver to Cahill Gordon & Reindel and to Greenberg, Traurig, Hoffman, Lipoff,
Rosen & Quentel, P.A. with respect to Parent and Merger Sub at the Closing
representation letters in form and substance sufficient to enable such counsel
to render the opinions required by Section 7.02(b) and Section 7.03(b).




<PAGE>
                                      -33-


                                    ARTICLE V

                     CONDUCT OF BUSINESS PENDING THE MERGER


     SECTION 5.01. Conduct of Business by the Company Pending the Merger. The
Company covenants and agrees that, between the date of this Agreement and the
Effective Time, except as set forth in Section 5.01 of the Company's Disclosure
Schedule, or as otherwise expressly provided for in this Agreement, unless
Parent expressly shall otherwise agree (which agreement shall not be
unreasonably withheld or delayed) in writing, the Company Business shall be
conducted only in, and the Company shall not take any action except in, the
ordinary course of business and in a manner consistent in all material respects
with past practice; and the Company shall use its reasonable efforts to preserve
intact its business organization, to keep available the services of the current
officers, employees and consultants of the Company and to preserve the current
relationships of the Company with customers, distributors, suppliers, licensors,
licensees, contractors and other persons with which the Company has significant
business relations and the Company will take no action not authorized hereby
which would adversely affect its ability to consummate the Merger or the other
transactions contemplated hereby. By way of amplification and not limitation,
except as expressly provided for in this Agreement, or as set forth in Section
5.01 of the Company Disclosure Schedule, the Company shall not, between the date
of this Agreement and the Effective Time, directly or indirectly do, or propose
to do, any of the following without the prior written consent of Parent, which
consent shall not be unreasonably withheld or delayed:

     (a) amend or otherwise change its Articles of Incorporation or By-laws;

     (b) issue, sell, license, transfer, pledge, dispose of, grant or encumber,
or authorize the issuance, sale, pledge, disposition, grant or encumbrance of,
(i) any shares of capital stock of any class of the Company, or any options,
warrants, convertible securities or other rights of any kind to acquire any
shares of such capital stock, or any other ownership interest (including,
without limitation, any phantom interest), of the Company or (ii) any assets of
the Company, except for sales of assets in the ordinary course of business and
in a manner consistent in all material respects with past practice;



<PAGE>
                                      -34-


     (c) set aside, make or pay any dividend or other distribution, payable in
cash, stock, property or otherwise, with respect to any of its capital stock;

     (d) reclassify, combine, split, subdivide or redeem, purchase or otherwise
acquire, directly or indirectly, any of its capital stock;

     (e) (i) acquire (including, without limitation, by merger, consolidation or
acquisition of stock or assets) any corporation, partnership, limited liability
company, other business organization or any division thereof, or any material
amount of assets or securities other than assets acquired in the ordinary course
of business and consistent with past practices; or (ii) enter into or amend any
contract with respect to any matter set forth in this subsection (e);

     (f) (i) incur any indebtedness for borrowed money or issue any debt or
assume, guarantee or endorse, or otherwise as an accommodation become
responsible for, the obligations of any person, or make any loans or advances,
except, in the case of indebtedness for borrowed moneys, in the ordinary course
of business and consistent in all material respects with past practice but in no
event in an amount in excess of $500,000 in the aggregate; (ii) authorize
capital expenditures which are, in the aggregate, in excess of $500,000 for the
Company; (iii) enter into or amend any contract, agreement, commitment or
arrangement material to the Company; or (iv) incur any liabilities except for
liabilities which, individually or in the aggregate, would not have a Company
Material Adverse Effect;

     (g) increase (except in the ordinary course of business and consistent in
all material respects with past practice) the compensation payable or to become
payable to its officers or employees generally, or except with respect to annual
bonuses approved at the Company's Board of Directors meeting held on December 9,
1997 and specified on Section 5.01 of the Company's Disclosure Schedule, grant
any bonus, severance (except as consistent with past practice and not in excess
of three months base salary without the written consent of Parent) or
termination pay to, or enter into any employment, consulting or severance
agreement with any person, or pay or agree to pay any pension, retirement or
other benefit (except as required under agreements, plans or other arrangements
existing as of September 30, 1997), establish, adopt, enter into, become
obligated under or amend any collective bargaining, bonus, profit sharing,
thrift, compensation, stock option, restricted stock, pension, retirement,
deferred compensation, employment, termi-



<PAGE>
                                      -35-


nation, severance, welfare, multiemployer, employee benefit or other plan,
agreement, trust, fund, policy or arrangement for the benefit of any past or
present director, officer or employee;

     (h) make any change in tax accounting methods or make any material tax
election or settle or compromise any material federal, state, local or foreign
income tax liability;

     (i) take any action that would or is reasonably likely to result in any of
the covenants and agreements set forth in this Article V or in Article VI or any
of the conditions set forth in Article VII not being satisfied as of the Closing
Date;

     (j) knowingly take any action that could reasonably be expected to prevent
the Merger from constituting a transaction qualifying under Section 368(a) of
the Code; or

     (k) except for the payment of reasonable professional fees relating to the
Merger or otherwise and reasonable fees to financial advisors (which financial
advisory fees have heretofore been disclosed or are otherwise acceptable, to
Parent), pay, discharge or satisfy any claim, liability or obligation (absolute,
accrued, asserted or unasserted, contingent or otherwise) in an amount in excess
of $250,000 in the aggregate, other than the payment, discharge or satisfaction,
in the ordinary course of business and consistent in all material respects with
past practice, of liabilities reflected or reserved against in the Company 1997
Balance Sheet or subsequently incurred in the ordinary course of business and
consistent with past practice or collect, or accelerate the collection of, any
amounts owed (including accounts receivable) other than collection in the
ordinary course.

     (l) except in the ordinary course of business or as otherwise expressly
contemplated hereby, grant or acquire any material licenses to use any
Intellectual Property Rights or unpatented inventions set forth in Section 3.11
of the Company Disclosure Schedule; provided that the Company shall not grant
any material licenses to use any material Intellectual Property Rights or
unpatented inventions so set forth without the prior written consent of Parent,
which consent shall not be unreasonably withheld;

     (m) except as otherwise expressly contemplated hereby, enter into any other
agreements, commitments or contracts, except agreements, commitments or
contracts for the 



<PAGE>
                                      -36-


purchase, sale or lease of goods or services in the ordinary course of business
and consistent in all material respects with past practice;

     (n) authorize, recommend, propose or announce an intention to authorize,
recommend or propose, or enter into any agreement in principle or an agreement
with any other person with respect to, any plan of liquidation or dissolution,
any disposition of a material amount of assets or securities or any material
change in the Company's capitalization, or any entry into a material contract or
any amendment or modification of any material contract or any release or
relinquishment of any material contract rights not in the ordinary course of
business and consistent with past practice except as expressly contemplated by
this Agreement;

     (o) permit any insurance policy naming it as a beneficiary or a loss payee
to be cancelled, terminated or materially altered, except in the ordinary course
of business and consistent in all material respects with past practice and
following written notice to Parent;

     (p) maintain its books and records in a manner not in the ordinary course
of business and substantially consistent with past practice;

     (q) enter into any hedging, option, derivative or other similar
transaction;

     (r) institute any change in its accounting methods, principles or practices
or revalue any of its respective assets, including without limitation, writing
down the value of inventory or writing off notes or accounts receivables;

     (s) agree to do any of the foregoing.


                                   ARTICLE VI

                              ADDITIONAL AGREEMENTS


     SECTION 6.01. Registration Statement; Proxy Statement.

     (a) As promptly as practicable after the execution of this Agreement, the
Company, with the assistance of Parent, shall prepare and file with the SEC
preliminary proxy materials 



<PAGE>
                                      -37-


relating to the meeting of the holders of shares of Company Common Stock to be
held in connection with the Merger (together with any amendments thereof or
supplements thereto, the "Proxy Statement"). Parent shall furnish all financial
and other information relating to it as the Company may reasonably request in
connection with the preparation of the Proxy Statement. As promptly as
practicable after comments are received from the SEC on the preliminary proxy
materials and after the furnishing by the Company and Parent of all information
required to be contained therein, Parent shall, with the assistance of the
Company, prepare and file with the SEC a registration statement on Form F-4
(together with all amendments thereto, the "Registration Statement"), in which
the Proxy Statement shall be included as a prospectus in connection with the
registration under the Securities Act of the Parent ADSs to be issued to the
holders of shares of Company Common Stock pursuant to the Merger. The Company
shall use all commercially reasonable efforts to have the Proxy Statement
cleared by the staff of the SEC and Parent shall use all commercially reasonable
efforts to cause the Registration Statement to become effective as promptly as
practicable, and shall take all action required under any applicable federal or
state securities laws in connection with the issuance of shares of Parent Common
Stock pursuant to the Merger. The Company shall furnish all information
concerning the Company as Parent may reasonably request in connection with such
actions and the preparation of the Registration Statement. As promptly as
practicable after the Registration Statement shall have become effective, the
Company shall mail the Proxy Statement to its stockholders.

     (b) The Registration Statement and the information supplied by Parent for
inclusion in the Proxy Statement shall not, at (i) the time the Registration
Statement is declared effective by the SEC; (ii) the time the Proxy Statement
(or any amendment thereof or supplement thereto) is first mailed to the holders
of shares of Company Common Stock; (iii) the time of the Shareholders' Meeting
(as defined in Section 6.02); and (iv) the Effective Time, contain any untrue
statement of a material fact or omit to state any material fact required to be
stated therein or necessary in order to make the statements therein not
misleading. If at any time prior to the Effective Time any event or circumstance
relating to Parent or any of its subsidiaries, or their respective officers or
directors, is discovered by Parent which should be set forth in an amendment or
a supplement to the Registration Statement or Proxy Statement, Parent shall
promptly inform the Company, and the Company shall make appropriate amendments
or supplements to the Proxy Statement. The Registration Statement shall comply
in all ma-



<PAGE>
                                      -38-


terial respects as to form and substance with the requirements of the Securities
Act, the Exchange Act and the rules and regulations thereunder. Notwithstanding
the foregoing, Parent and Merger Sub make no representations or warranties with
respect to any information supplied by the Company which is contained in, or
furnished in connection with the preparation of, any of the foregoing documents.

     (c) The Proxy Statement and the information supplied by the Company for
inclusion in the Registration Statement shall not, at (i) the time the
Registration Statement is declared effective by the SEC; (ii) the time the Proxy
Statement (or any amendment thereof or supplement thereto) is first mailed to
the holders of shares of Company Common Stock; (iii) the time of the
Shareholders' Meeting; and (iv) the Effective Time, contain any untrue statement
of a material fact or omit to state any material fact required to be stated
therein or necessary in order to make the statements therein not misleading. If
at any time prior to the Effective Time any event or circumstance relating to
the Company or any of the Subsidiaries, or their respective officers or
directors, is discovered by the Company which should be set forth in an
amendment or a supplement to the Registration Statement or Proxy Statement, the
Company shall promptly inform Parent and an amendment or supplement shall be
promptly filed with the SEC and, as required by law, disseminated to the
stockholders of the Company. The Registration Statement and the Proxy Statement
shall comply in all material respects as to form and substance with the
requirements of the Securities Act, the Exchange Act and the rules and
regulations thereunder. Notwithstanding the foregoing, the Company makes no
representation or warranty with respect to any information supplied by Parent or
Merger Sub which is contained in, or furnished in connection with the
preparation of, any of the foregoing documents.

     SECTION 6.02. Shareholders' Meeting.

     The Company shall take all action necessary in accordance with applicable
law and its Restated Articles of Incorporation and By-laws to call and convene a
special meeting of its stockholders (the "Special Meeting") as soon as
practicable to consider and vote upon the approval of this Agreement. The
Company, through its Board of Directors, (i) shall recommend to its shareholders
approval of this Agreement, which recommendation shall be contained in the Proxy
Statement; provided, however, that the Board of Directors of the Company may
fail to make its recommendation to the shareholders of the Company or may
withdraw, modify or change its recommendation to 



<PAGE>
                                      -39-


the shareholders of the Company, in response to an unsolicited bona fide,
written proposal from a corporation, partnership, person, or other entity or
group regarding a Superior Proposal (as hereinafter defined in Section 6.05),
but only if the Company's Board of Directors determines in good faith by a
majority vote that withdrawing, modifying or changing its recommendation is
reasonably likely to lead to an Acquisition Transaction (as hereinafter defined
in Section 6.05) that is more favorable to the shareholders of the Company than
the Merger and that failing to take such action could reasonable be expected to
constitute a breach of such Board's fiduciary duties, having received prior to
such determination (x) advice of outside legal counsel of the Company that
failing to take such action could reasonably be expected to constitute a breach
of the fiduciary duties of such Board of Directors, and (y) the advice of a
financial advisor of nationally recognized reputation that the Superior Proposal
could reasonably be expected to provide greater value to the Company and its
shareholders than the Merger and (ii) shall use all commercially reasonable
efforts to solicit from its shareholders proxies regarding approval and adoption
of this Agreement.

     SECTION 6.03. Appropriate Action; Consents; Filings.

     (a) Subject to the terms and conditions herein provided, the Company and
Parent shall use their commercially reasonable efforts, to (i) take, or cause to
be taken, all appropriate action and do, or cause to be done, all things
necessary, proper or advisable under applicable Law or otherwise to consummate
and make effective the Merger as promptly as practicable, (ii) obtain
expeditiously from any Governmental Authorities or third parties any consents,
licenses, permits, waivers, approvals, authorizations or orders required to be
obtained or made by Parent or the Company or any of their Subsidiaries in
connection with the authorization, execution and delivery of this Agreement and
the consummation of the Merger, and (iii) as promptly as practicable, make all
necessary filings, and thereafter make any other required submissions, with
respect to this Agreement and the Merger required under (A) the Securities Act
and the Exchange Act, and any other applicable federal or state securities Laws,
(B) the HSR Act and any related governmental request thereunder and (C) any
other applicable Law; provided that Parent and the Company shall cooperate with
each other in connection with the making of all such filings, including
providing copies of all such documents to the non-filing party and its advisors
prior to filing and, if requested, accepting all reasonable additions, deletions
or changes suggested by the 



<PAGE>
                                      -40-


other party in connection therewith. From the date of this Agreement until the
Effective Time, each party shall promptly notify the other party in writing of
any pending or, to the knowledge of the first party, threatened action,
proceeding or investigation by any Governmental Authority or any other person
(i) challenging or seeking material damages in connection with the Merger or the
conversion of the Company Common Stock into Parent ADSs pursuant to the Merger
or (ii) seeking to restrain or prohibit the consummation of the Merger or
otherwise limit the right of Parent or Parent's subsidiaries to own or operate
all or any portion of the businesses or assets of the Company, which in either
case would have a Company Material Adverse Effect prior to or after the
Effective Time, or a Parent Material Adverse Effect after the Effective Time.

     (b) The Company and Parent shall furnish to each other all information
required for any application or other filing to be made pursuant to the rules
and regulations of any applicable Law (including all information required to be
included in the Proxy Statement and the Registration Statement) in connection
with the transactions contemplated by this Agreement.

     SECTION 6.04. Access to Information; Confidentiality.

     (a) The parties shall comply with, and shall cause their respective
Representatives (as defined below) to comply with, to the extent permitted by
applicable Law, all of their respective obligations under the Confidentiality
Agreement (the "Confidentiality Agreement") previously entered into between the
Company and Parent.

     (b) Subject to the Confidentiality Agreement, from the date hereof to the
Effective Time, each party hereto will provide to the other party (and its
officers, directors, employees, accountants, consultants, legal counsel,
financial advisors, agents and other representatives, collectively,
"Representatives") access to all information and documents which any such party
may reasonably request regarding the business, assets, liabilities, employees
and other aspects of the other party.

     (c) From the date hereof to the Effective Time, each party hereto shall:
(i) provide to the other party and its Representatives access at reasonable
times upon prior notice to its officers, employees, agents, properties, offices
and other facilities and its Subsidiaries and to the books and records 



<PAGE>
                                      -41-


thereof and (ii) furnish promptly such information concerning the business,
properties, contracts, assets, liabilities, personnel and other aspects of such
party and its Subsidiaries as a party hereto or its Representatives may
reasonably request.

     (d) Parent and Merger Sub agree to treat confidentially all confidential
information concerning the Company which is furnished to Parent and Merger Sub
or their Representatives by or on behalf of the Company whether before or after
the date of this Agreement. Parent and Merger Sub agree that such information
shall be used solely for the purposes of the Agreement, the Merger and the
transactions contemplated hereby. Except as required by law or stock exchange
regulations (and then only with prior written notice to the Company of such
requirement), neither Parent and Merger Sub nor its Representatives shall
disclose to any person any such information. In the event that this Agreement is
terminated pursuant to Article VIII, Parent and Merger Sub shall, and shall
direct their Representatives to, promptly upon the written request of the
Company deliver to the Company all written material received from the Company
and will keep confidential or destroy any analyses, compilations, studies or
other documents prepared by Parent or Merger Sub or its Representatives
reflecting information furnished by or on behalf of the Company, without
returning a copy thereof.

     (e) The Company agrees to keep confidential all information concerning
Parent and Merger Sub furnished to the Company or its Representatives by or on
behalf of the Parent to the same extent that the Parent and Merger Sub are
obligated pursuant to Section 6.04(d) to keep confidential information furnished
by or on behalf of the Company confidential.

     SECTION 6.05. No Solicitation. (a) The Company agrees that, prior to the
Effective Time, it shall not, and shall not authorize or permit any of its
directors, officers, employees, agents or representatives to, directly or
indirectly, solicit, initiate, facilitate or encourage (including by way of
furnishing or disclosing non-public information) any inquiries or the making of
any proposal with respect to any merger, consolidation or other business
combination involving the Company or acquisition of any kind of any material
portion of the assets or capital stock of the Company (an "Acquisition
Transaction") or negotiate, explore or otherwise communicate in any way with any
third party with respect to any Acquisition Transaction or enter into any
agreement, arrangement or understanding requiring it to abandon, terminate or
fail to consummate the Merger or any 



<PAGE>
                                      -42-


other transactions contemplated by this Agreement; provided, however, that the
Company, its Board of Directors, officers, employees, agents and representatives
may, in response to an unsolicited bona fide, written proposal from a Third
Party regarding a Superior Proposal (as hereinafter defined) furnish information
to, engage in discussions and negotiate with such Third Party, but only if the
Board of Directors of the Company determines in good faith by a majority vote
that taking such action is reasonably likely to lead to an Acquisition
Transaction that is more favorable to the stockholders of the Company than the
Merger and that failing to take such action could reasonably be expected to
constitute a breach of the Board's fiduciary duties, having received prior to
such determination of advice of outside legal counsel of the Company that
failing to take such action could reasonably be expected to constitute a breach
of the fiduciary duties of the Board of Directors and the advice of a financial
advisor of nationally recognized reputation that the Superior Proposal could
reasonably be expected to provide greater value to the Company and its
stockholders than the Merger. As used herein, "Superior Proposal" means a bona
fide, written and unsolicited offer made by any financially responsible third
party (other than Parent) with respect to an Acquisition Transaction for which
any required financing is committed in writing by reputable financing sources.

     (b) The Company shall immediately notify the Parent of (i) receipt of any
proposal relating to an Acquisition Transaction or any request for non-public
information relating to the Company in connection with an Acquisition
Transaction or for access to the properties, books or records of the Company by
any person or entity that informs the Board of Directors of the Company that it
is considering making, or has made, a proposal relating to an Acquisition
Transaction and (ii) any action, failure to act, determination or resolution by
the Company or its Board of Directors referred to in Sections 6.02, 6.05(a),
8.01(f), 8.01(g) or 8.01(h). Such notice to the Parent shall be made orally and
in writing and shall include a copy of any writing submitted by such person or
entity and shall indicate in reasonable detail the identity of the offeror and
the terms and conditions of such proposal, inquiry or contract.

     (c) During the period from the date of this Agreement through the Effective
Time, the Company shall not terminate, amend, modify or waive any provision of
any confidentiality or standstill agreement to which it is a party. During such
period, the Company shall enforce, to the fullest extent 



<PAGE>
                                      -43-


permitted under applicable law, the provisions of any such agreement, including,
but not limited to, by obtaining injunctions to prevent any breaches of any such
agreement and to enforce specifically the terms and provisions thereof in any
court of the United States of America or of any state having jurisdiction.

     SECTION 6.06. Indemnification and Insurance.

     (a) Parent and the Surviving Corporation agree that, except as may be
limited by applicable Laws, for seven (7) years from and after the Effective
Time, the indemnification obligations set forth in the Company's Articles of
Incorporation and the Company's By-Laws, or in any indemnification agreement to
which the Company is a party as of September 30, 1997, in each case as of the
date of this Agreement, shall survive the Merger and shall not be amended,
repealed or otherwise modified after the Effective Time in any manner that would
adversely affect the rights thereunder of the individuals who on or at any time
prior to the Effective Time were entitled to indemnification thereunder with
respect to matters occurring at or prior to the Effective Time.

     (b) The Surviving Corporation shall maintain in effect, for three (3) years
from and after the Effective Time, directors' and officers' liability insurance
policies covering the persons who are currently covered in their capacities as
such directors and officers by the Company's current directors' and officers'
policies and on terms not less favorable than the existing insurance coverage
with respect to matters occurring prior to the Effective Time; provided,
however, that the Surviving Corporation shall not be obligated to make annual
premium payments for such insurance solely with respect to such premium amounts
that exceed 150% of the annual premiums paid as of the date hereof by the
Company for such insurance.

     (c) Parent hereby guarantees, effective upon the consummation of the
Merger, the Surviving Corporation's obligations under Section 6.06(a) and (b) of
this Agreement.

     SECTION 6.07. Notification of Certain Matters. (a) From and after the date
of this Agreement until the Effective Time, each party hereto shall promptly
notify the other parties hereto of (i) the occurrence, or non-occurrence, of any
event the occurrence or non-occurrence of which would be reasonably likely to
cause any condition to the obligations of any party to effect the Merger not to
be satisfied, or (ii) the failure of the Company or Parent, as the case may be,
to comply with or 



<PAGE>
                                      -44-


satisfy any covenant, condition or agreement to be complied with or satisfied by
it pursuant to this Agreement which would be reasonably likely to result in any
condition to the obligations of any party to effect the Merger not to be
satisfied.

     (b) The Company shall give prompt notice to Parent of any notice of, or
other communication relating to, a default or event which, with notice or lapse
of time or both, would become a default, received by the Company subsequent to
the date of this Agreement and prior to the Effective Time, under any contract
material to the general affairs, management, business, operations, assets or
condition (financial or otherwise) or prospects of the Company and shall keep
Parent and Merger Sub informed of all non-routine actions the Company intends to
take in connection with any Environmental Law and all actions shall be on terms
and conditions reasonably satisfactory to Parent and Merger Sub. Each of the
Company and Parent shall give prompt notice to the other party of (i) any notice
or other communication from any third party alleging that the consent of such
third party is or may be required in connection with the Merger or other
transactions contemplated hereby, (ii) any change or prospective change that is
likely to have, respectively, a Company Material Adverse Effect or Parent
Material Adverse Effect or (iii) the occurrence or existence of any event which
would, with the passage of time or otherwise, make any representation or
warranty contained herein untrue. The delivery of any notice pursuant to Section
6.07(a) shall not be deemed to be an amendment of this Agreement or any Section
in the Company Disclosure Schedule and shall not cure any breach of any
representation or warranty requiring disclosure of such matter prior to the date
of this Agreement. No delivery of any notice pursuant to this Section 6.07 shall
limit or affect the remedies available hereunder to the party receiving such
notice, including the rights of Parent under Section 7.02(a) and those of the
Company under Section 7.03(a), in the event that a representation or warranty
made by the Company or Parent herein shall not be true and correct (giving
effect to any standards of materiality set forth in such Sections) as of the
date hereof or as of the date when made (if a different date) and as of the
Effective Time.

     SECTION 6.08. Stock Exchange Listing. Parent shall as promptly as
reasonably practicable prepare and submit to the NYSE a listing application
covering the Parent ADSs to be issued in the Merger and shall use its reasonable
efforts to cause such shares to be approved for listing on the NYSE prior to the
Effective Time, and Parent shall use its reasonable 



<PAGE>
                                      -45-


effort to cause the Parent Ordinary Shares, represented by Parent ADSs,
constituting the Merger Consideration to be admitted (subject to allotment) to
the Official List of the Irish Stock Exchange and the London Stock Exchange.

     SECTION 6.09. Public Announcements. Parent and the Company shall consult
with each other before issuing any press release or otherwise making any public
statements with respect to this Agreement or any transaction contemplated
hereby. Parent and the Company shall not issue any such press release or make
any such public statement without the prior consent of the other (which consent
shall not be unreasonably withheld), except as may be required by Law or any
listing agreement with the NYSE, the NASD or any national securities exchange,
including the Irish Stock Exchange and the London Stock Exchange, to which
Parent or the Company is a party. The parties have agreed on the text of a joint
press release by which Parent and the Company will announce the execution of
this Agreement.

     SECTION 6.10. Plan of Reorganization. This Agreement is intended to
constitute a "plan of reorganization" within the meaning of Section 1.368-2(g)
of the income tax regulations promulgated under the Code.

     SECTION 6.11. Compensation. Parent shall cause the Surviving Corporation to
offer compensation and benefits to such corporation's employees that are
substantially equivalent to the compensation and benefits that such employees
enjoyed before the Effective Time; provided that nothing in this Section 6.11
shall obligate the Surviving Corporation to renew any employment agreements
after their expiration or termination.

     SECTION 6.12. Compliance With Tax Requirements.

     (a) To avoid the application of Section 367(a)(1) of the Code, Parent
covenants that, after the Closing, Parent will ensure that the Company complies
with the reporting requirements in Treasury Regulation Section 1.367(a)-3(c)(6).

     (b) Parent shall provide to the Company stockholders who receive Parent
ADSs in the Merger any information concerning Parent necessary to comply with
the requirements of Section 6038B of the Code and Treasury Regulation Section
1.6038B-1T (or any successor Regulation).




<PAGE>
                                      -46-


                                   ARTICLE VII

                            CONDITIONS TO THE MERGER


     SECTION 7.01. Conditions to the Obligations of Each Party. The obligations
of the Company, Parent and Merger Sub to consummate the Merger are subject to
the satisfaction or, if permitted by applicable Law, waiver of the following
conditions:

     (a) this Agreement and the transactions contemplated hereby shall have been
approved and adopted by the affirmative vote of the holders of a majority of the
outstanding shares of Company Common Stock in accordance with Florida Law and
the Company's Articles of Incorporation;

     (b) all material authorizations, orders, consents, licenses, confirmations,
clearances, permissions and approvals which may be required in any jurisdiction
for the purposes of applicable anti-trust, competition, takeover or similar
legislation in connection with the consummation of the Merger and the other
transactions contemplated hereby shall have been received and shall remain in
full force and effect, including without limitation, any applicable waiting
period under the HSR Act relating to the Merger shall have expired or been
terminated;

     (c) no order, statute, rule, regulation, executive order, stay, decree,
judgment or injunction shall have been enacted, entered, issued, promulgated or
enforced by any Governmental Authority or a court of competent jurisdiction
which has the effect of making the Merger illegal or otherwise prohibiting
consummation of the Merger; and

     (d) the Registration Statement shall have been declared effective, and no
stop order suspending the effectiveness of the Registration Statement shall be
in effect and no proceedings for such purpose shall be pending before or
threatened by the SEC.

     SECTION 7.02. Conditions to the Obligations of Parent and Merger Sub. The
obligation of Parent and Merger Sub to effect the Merger and to perform their
other obligations to be performed at or subsequent to the Closing shall be
subject to the fulfillment at or prior to the Closing of the following
additional conditions, any one or more of which may be waived by Parent or
Merger Sub:



<PAGE>
                                      -47-


     (a) (i) The Company shall have performed in all material respects all of
its obligations hereunder required to be performed by it at or prior to the
Effective Time and (ii) the representations and warranties of the Company that
are qualified with reference to a Company Material Adverse Effect or materiality
shall be true and correct and the representations and warranties of the Company
that are not so qualified shall be true and correct in all material respects, in
each case as of the date hereof, and, except to the extent such representations
and warranties speak as of an earlier date, as of the Effective Time as though
made at and as of the Effective Time.

     (b) Parent shall have received an opinion of Cahill Gordon & Reindel,
counsel to Parent, dated on or about the Closing Date, and such other facts,
representations and assumptions as counsel may reasonably deem relevant, to the
effect that the Merger will be treated for federal income tax purposes as a
reorganization qualifying under the provisions of Section 368(a) of the Code;
that each of Parent, Merger Sub and the Company will be a party to the
reorganization within the meaning of Section 368(b) of the Code; and that no
gain or loss will be recognized by a stockholder of the Company on the
conversion of Company Common Stock into Parent ADSs pursuant to the Merger
(except with respect to any cash received in lieu of a fractional share),
provided that (i) Company complies with the reporting requirements contained in
Treasury Regulation Section 1.367(a)-3(c)(6), (ii) the Company stockholder owns
(including beneficial, indirect and constructive ownership) less than five
percent of the total voting power and total value of Parent's outstanding stock
immediately after the Merger, and (iii) the Company stockholder complies with
the notice requirements of Section 6038B of the Code; and

     (c) Since September 30, 1997, there shall not have occurred any material
adverse change in the general affairs, management, business, operations, assets
or condition (financial or otherwise) of the Company (including loss of a
significant portion of the employees in the Company's research department).

     (d) All the consents and approvals, and notifications and disclosures, and
filings and registrations listed in Sections 3.05(b) and 4.05(b) hereof shall
have been obtained.

     (e) Parent shall have received agreements, in substantially the form
attached hereto as Exhibit 7.02, restricting such individual's ability to
dispose of Parent ADSs held by 


<PAGE>
                                      -48-


such individual for a period of one year from the Effective Date.

     SECTION 7.03. Conditions to the Obligations of the Company. The obligations
of the Company under this Agreement to effect the Merger shall be subject to the
fulfillment on or before the Closing Date of each of the following additional
conditions, any one or more of which may be waived by the Company:

     (a) (i) Parent and Merger Sub shall have performed in all material respects
all of their obligations hereunder required to be performed by them at or prior
to the Effective Time and (ii) the representations and warranties of Parent and
Merger Sub that are qualified with reference to a Parent Material Adverse Effect
or materiality shall be true and correct and the representations and warranties
of Parent and Merger Sub that are not so qualified shall be true and correct in
all material respects, in each case as of the date hereof, and, except to the
extent such representations and warranties speak as of an earlier date, as of
the Effective Time as though made at and as of the Effective Time.

     (b) The Company shall have received an opinion of Greenberg Traurig Hoffman
Lipoff Rosen & Quentel, P.A., counsel to the Company, dated on or about the
Closing Date, and such other facts, representations and assumptions as counsel
may reasonably deem relevant, to the effect that the Merger will be treated for
federal income tax purposes as a reorganization qualifying under the provisions
of Section 368(a) of the Code; that each of Parent, Merger Sub and the Company
will be a party to the reorganization within the meaning of Section 368(b) of
the Code; and that no gain or loss will be recognized by a stockholder of the
Company on the conversion of Company Common Stock into Parent ADSs pursuant to
the Merger (except with respect to any cash received in lieu of a fractional
share), provided that (i) Company complies with the reporting requirements
contained in Treasury Regulation Section 1.367(a)-3(c)(6), (ii) the Company
stockholder owns (including beneficial, indirect and constructive ownership)
less than five percent of the total voting and total value of Parent's
outstanding stock immediately after the Merger, and (iii) the Company
stockholder complies with the notice requirements of Section 6038B of the Code;

     (c) The Company shall have received an opinion from counsel to the Parent
concerning the matters set forth in Sections 4.01, 4.03 and 4.04 hereof;


<PAGE>
                                      -49-


     (d) Since September 30, 1997, there shall not have occurred any material
adverse change in the general affairs, management, business, operations, assets
or condition (financial or otherwise) of Parent and its subsidiaries taken as a
whole;

     (e) The Company's Board of Directors shall have received prior to the date
the Registration Statement is submitted to the SEC, and the Company shall have
included in the Proxy Statement, the written Fairness Opinion of the Company
Financial Advisor, to the effect that the financial terms of the Merger are fair
to the shareholders of the Company from a financial point of view, in form and
substance reasonably satisfactory to the Company;

     (f) The Average Parent Trading Price shall be not less than $44.1625; and

     (g) All the consents and approvals, and notifications and disclosures, and
filings and registrations listed in Sections 3.05(b) and 4.05(b) hereof shall
have been obtained, including the Parent ADSs to be issued in the Merger shall
have been authorized for listing on the NYSE, the London Stock Exchange and the
Dublin Stock Exchange, subject to official notice of issuance.


                                  ARTICLE VIII

                        TERMINATION, AMENDMENT AND WAIVER


     SECTION 8.01. Termination. This Agreement may be terminated and the Merger
may be abandoned at any time prior to the Effective Time, notwithstanding any
requisite approval and adoption of this Agreement and the transactions
contemplated hereby by the shareholders of the Company:

          (a) by written consent duly authorized by the Boards of Directors of
     each of Parent and the Company;

          (b) by either Parent or the Company if (i) the waiting period
     applicable to the consummation of the Merger under the HSR Act shall not
     have expired or been terminated prior to June 30, 1998, (ii) any court of
     competent jurisdiction in the United States or other United States
     Governmental Authority shall have issued an order (other than a temporary
     restraining order), decree or ruling, or 


<PAGE>
                                      -50-


     taken any other action, restraining, enjoining or otherwise prohibiting the
     Merger (provided, however, that neither party may terminate this Agreement
     pursuant to this Section 8.01(b)(ii) prior to June 30, 1998 if the party
     subject to such order, decree or ruling is using its reasonable best
     efforts to have such order, decree or ruling removed, unless such order,
     decree or ruling shall have become final and non-appealable), or (iii) the
     Effective Time shall not have occurred on or before June 30, 1998; provided
     that the right to terminate this Agreement under this Section 8.01(b) shall
     not be available to any party whose willful, deliberate or knowing failure
     to fulfill any obligation under this Agreement has been the cause of, or
     resulted in, the failure of the Effective Time to occur on or before such
     date;

          (c) by either Parent or the Company, if the Shareholders' Meeting
     shall have been held and the holders of outstanding shares of Company
     Common Stock shall have failed to approve and adopt this Agreement at such
     meeting (including any adjournment or postponement thereof);

          (d) by the Company, upon a breach of any representation, warranty, or
     agreement set forth in this Agreement such that the condition set forth in
     Section 7.03(a) would not be satisfied (a "Terminating Parent Breach");
     provided, however, that, if such Terminating Parent Breach is curable by
     Parent through the exercise of its best efforts and Parent continues to
     exercise such best efforts, the Company may not terminate this Agreement
     under this Section 8.01(d) for a period of 30 days from the date on which
     the Company delivers to Parent written notice setting forth in reasonable
     detail the circumstances giving rise to such Terminating Parent Breach;

          (e) by Parent, upon a breach of any representation, warranty, or
     agreement set forth in this Agreement such that the condition set forth in
     Section 7.02(a) would not be satisfied (a "Terminating Company Breach");
     provided, however, that, if such Terminating Company Breach is curable by
     the Company through the exercise of its best efforts and the Company
     continues to exercise such best efforts, Parent may not terminate this
     Agreement under this Section 8.01(e) for a period of 30 days from the date
     on which Parent delivers to the Company written notice setting forth in
     reasonable detail the circumstances giving rise to such Terminating Company
     Breach;


<PAGE>
                                      -51-


          (f) by Parent if the Board of Directors of the Company (i) fails to
     recommend the approval of this Agreement and the Merger to the Company's
     stockholders, (ii) withdraws or amends or modifies in a manner adverse to
     the Parent its recommendation or approval in respect of this Agreement or
     the Merger, or (iii) makes any recommendation with respect to an
     Acquisition Transaction (including making no recommendation or stating an
     inability to make a recommendation), other than a recommendation to reject
     such Acquisition Transaction, or the Board of Directors of the Company
     shall have resolved to take any of the foregoing actions referred to in
     this clause and publicly discloses such resolution;

          (g) by Parent, if the Company or its representatives shall furnish or
     disclose non-public information or negotiate, discuss, explore or otherwise
     communicate in any way with a third party with respect to any Acquisition
     Transaction, or the Board of Directors of the Company shall have resolved
     to take any of the foregoing actions referred to in this clause and
     publicly discloses such resolution; provided, however, that in such event
     Parent shall have no right to terminate pursuant to this clause (g) until
     February 15, 1998, and only if the Company has not terminated all such
     activities prior to such date; or

          (h) by the Company (A) if the Company shall have received a Superior
     Proposal and (B) the Board of Directors of the Company, having received (x)
     the advice of outside legal counsel of the Company relating thereto and (y)
     the advice of a financial advisor of nationally recognized reputation
     relating thereto, reasonably determines in good faith that such Superior
     Proposal is more favorable to the Company and its stockholders than the
     Merger and is reasonably likely to be consummated and that failing to take
     such action would be inconsistent with their fiduciary duties to the
     stockholders of the Company, and (C) the Company shall have given Parent
     five business days prior notice of its determination to terminate this
     Agreement.

          (i) by the Company, on such date as the sole closing condition under
     either Sections 7.01 and 7.03 herein that remains unsatisfied is subsection
     7.03(f) (assuming for purposes of calculating the Average Parent Trading
     Price that the Closing Date is the date that all conditions in Sections
     7.01 and 7.03, other than Section 7.03(f), have been satisfied).


<PAGE>
                                      -52-


     SECTION 8.02. Effect of Termination. Except as provided in Section 9.01, in
the event of the termination of this Agreement pursuant to Section 8.01, this
Agreement shall forthwith become void, there shall be no liability under this
Agreement on the part of Parent, Merger Sub or the Company or any of their
respective officers or directors and all rights and obligations of any party
hereto shall cease; provided, however, that nothing herein shall relieve any
party from liability for, or be deemed to waive any rights of specific
performance of this Agreement available to a party by reason of, any willful
breach by the other party or parties of its or their willful breach of any of
its representations, warranties, covenants or agreements set forth in this
Agreement.

     SECTION 8.03. Fees and Expenses. (a) In the event that this Agreement is
terminated pursuant to Section 8.01(f), (g) or (h) herein, within fifteen (15)
days of such termination, the Company shall pay to Parent, in immediately
available funds to an account specified by Parent, a fee of $12,000,000, as
liquidated damages.

     (b) In the event of a termination of this Agreement by the Company pursuant
to Section 8.01(d), then Parent shall within two business days of such
termination pay the Company by wire transfer of immediately available funds to
an account specified by the Company up to $1 million to reimburse the Company
for its documented fees and expenses (including the fees and expenses of
counsel, accountants, consultants and advisors) incurred in connection with this
Agreement and the transactions contemplated hereby. In the event of a
termination of this Agreement by Parent pursuant to Section 8.01(e), then the
Company shall within two business days of such termination pay Parent by wire
transfer of immediately available funds to an account specified by Parent up to
$1 million to reimburse Parent for its documented fees and expenses (including
the fees and expenses of counsel, accountants, consultants and advisors)
incurred in connection with this Agreement and the transactions contemplated
hereby.

     (c) Except as provided in Section 8.03(b), all expenses incurred by the
parties hereto shall be borne solely and entirely by the party which has
incurred the same; provided, however, that (i) Parent and the Company shall bear
equally all expenses related to printing, filing and mailing the Registration
Statement and the Proxy Statement and all SEC filing fees and stock exchange
listing applications incurred in connection with the Registration Statement and
the Proxy Statement and (ii) Parent shall bear all expenses incurred by the
parties 


<PAGE>
                                      -53-


hereto and their respective affiliates, if applicable, in connection with any
filing under the HSR Act due to the transactions contemplated herein.

     (d) The Company acknowledges that the agreements contained in this Section
8.03 are an integral part of the transactions contemplated in this Agreement,
and that, without these agreements, Parent and Merger Sub would not enter into
this Agreement; accordingly, if the Company fails to promptly pay any amount
claimed pursuant to Section 8.03(a), and, in order to obtain such payment,
Parent or Merger Sub commences a suit against the Company for the fee set forth
in Section 8.03(a), the prevailing party shall be entitled to recover its costs
and expenses (including reasonable attorneys' fees) in connection with such
suit.

     SECTION 8.04. Amendment. This Agreement may be amended by the parties
hereto by action taken by or on behalf of their respective Boards of Directors
at any time prior to the Effective Time; provided that, after the approval and
adoption of this Agreement by the stockholders of the Company, no amendment may
be made which would reduce the amount or change the type of consideration to be
received by the stockholders of the Company pursuant to the Merger. This
Agreement may not be amended except by an instrument in writing signed by the
parties hereto.

     SECTION 8.05. Waiver. At any time prior to the Effective Time, any party
hereto may (a) extend the time for the performance of any obligation or other
act of any other party hereto, (b) waive any inaccuracy in the representations
and warranties of the other party contained herein or in any document delivered
by the other party pursuant hereto and (c) waive compliance with any agreement
or condition contained herein. Any such extension or waiver shall be valid if
set forth in an instrument in writing signed by the party or parties to be bound
thereby.


                                   ARTICLE IX

                               GENERAL PROVISIONS


     SECTION 9.01. Non-Survival of Representations, Warranties and Agreements.
The representations, warranties and agreements in this Agreement and any
certificate delivered pursuant hereto by any person shall terminate at the
Effective 


<PAGE>
                                      -54-


Time or upon the termination of this Agreement pursuant to Section 8.01, as the
case may be, except that the agreements set forth in Articles I and II and
Sections 6.06 and 6.12 shall survive the Effective Time for the periods stated
therein, and those set forth in Sections 6.09, 6.11, 8.02, 8.03, 8.04, 8.05 and
this Article IX shall survive termination indefinitely.

     SECTION 9.02. Notices. All notices, requests, claims, demands and other
communications hereunder shall be in writing and shall be given (and shall be
deemed to have been duly given upon receipt) by delivery in person, by facsimile
or by registered or certified mail (postage prepaid, return receipt requested)
or by a nationally recognized overnight courier service to the respective
parties at the following addresses (or at such other address for a party as
shall be specified in a notice given in accordance with this Section 9.02):

     if to Parent or Merger      Elan Corporation, plc
     Sub                         Lincoln House
                                 Lincoln Place
                                 Dublin 2, Ireland
                                 Telecopy:  (011)(353) 1-662-4963
                                 Attention:  Thomas G. Lynch

     with copies to:             Cahill Gordon & Reindel
                                 80 Pine Street
                                 New York, NY 10005
                                 Telecopy:  (212) 269-5420
                                 Attention:  William M. Hartnet

     if to the Company:          Sano Corporation
                                 3250 Commerce Parkway
                                 Miramar, Florida  33025
                                 Attention:  Reginald L. Hardy

     with a copy to:             Greenberg Traurig Hoffman Lipoff
                                   Rosen & Quentel, P.A.
                                 1221 Brickell Avenue
                                 Miami, Florida  33131
                                 Attention:  Gary M. Epstein, Esq.

     SECTION 9.03. Certain Definitions. For purposes of this Agreement, the
term:


<PAGE>
                                      -55-


          (a) "affiliate" of a specified person means a person who directly or
     indirectly through one or more intermediaries controls, is controlled by,
     or is under common control with, such specified person;

          (b) "beneficial owner" with respect to any shares means a person who
     shall be deemed to be the beneficial owner of such shares (i) which such
     person or any of its affiliates or associates (as such term is defined in
     Rule 12b-2 promulgated under the Exchange Act) beneficially owns, directly
     or indirectly, (ii) which such person or any of its affiliates or
     associates has, directly or indirectly, (A) the right to acquire (whether
     such right is exercisable immediately or subject only to the passage of
     time), pursuant to any agreement, arrangement or understanding or upon the
     exercise of consideration rights, exchange rights, warrants or options, or
     otherwise, or (B) the right to vote pursuant to any agreement, arrangement
     or understanding or (iii) which are beneficially owned, directly or
     indirectly, by any other persons with whom such person or any of its
     affiliates or associates or any person with whom such person or any of its
     affiliates or associates has any agreement, arrangement or understanding
     for the purpose of acquiring, holding, voting or disposing of any such
     shares;

          (c) "business day" means any day on which the principal offices of the
     SEC in Washington, D.C. are open to accept filings, or, in the case of
     determining a date when any payment is due, any day on which banks are not
     required or authorized to close in the City of New York, New York;

          (d) "Control" (including the terms "controlled by" and "under common
     control with") means the possession, directly or indirectly or as trustee
     or executor, of the power to direct or cause the direction of the
     management and policies of a person, whether through the ownership of
     voting securities, as trustee or executor, by contract or credit
     arrangement or otherwise;

          (e) "Governmental Authority" means any United States (federal, state
     or local), foreign or supra-national Government, or governmental,
     regulatory or administrative authority, agency or commission;

          (f) "Knowledge," solely with respect to the Company, means the actual
     knowledge of any of the members of the 


<PAGE>
                                      -56-


     Company's current Board of Directors or any of the executive officers of
     the Company.

          (g) "person" means an individual, corporation, limited liability
     company, partnership, limited partnership, syndicate, person (including,
     without limitation, a "person" as defined in Section 13(d)(3) of the
     Exchange Act), trust, association or entity or government, political
     subdivision, agency or instrumentality of a government;

          (h) "Subsidiary" or "Subsidiaries" of any person means any
     corporation, partnership, joint venture or other legal entity of which such
     person (either above or through or together with any other subsidiary),
     owns, directly or indirectly, 50% or more of the stock or other equity
     interests, the holders of which are generally entitled to vote for the
     election of the board of directors or other governing body of such
     corporation or other legal entity.

     SECTION 9.04. Accounting Terms. All accounting terms used herein which are
not expressly defined in this Agreement shall have the respective meanings given
to them in accordance with United States generally accepted accounting
principles.

     SECTION 9.05. Severability. If any term or other provision of this
Agreement is invalid, illegal or incapable of being enforced by any rule of Law,
or public policy, all other conditions and provisions of this Agreement shall
nevertheless remain in full force and effect so long as the economic or legal
substance of the Merger is not affected in any manner materially adverse to any
party. Upon such determination that any term or other provision is invalid,
illegal or incapable of being enforced, the parties hereto shall negotiate in
good faith to modify this Agreement so as to effect the original intent of the
parties as closely as possible in a mutually acceptable manner in order that the
Merger be consummated as originally contemplated to the fullest extent possible.

     SECTION 9.06. Entire Agreement; Assignment. This Agreement (including the
Exhibits and the Company Disclosure Schedule, which are hereby incorporated
herein and made a part hereof for all purposes as if fully set forth herein) and
the Confidentiality Agreement constitute the entire agreement among the parties
with respect to the subject matter hereof and supersede all prior agreements and
undertakings, both written and oral, among the parties, or any of them, with
respect to 


<PAGE>
                                      -57-


the subject matter hereof. This Agreement shall not be assigned by operation of
law or otherwise, except that Parent and Merger Sub may assign all or any of
their rights and obligations hereunder to any affiliate of Parent provided that
no such assignment shall change the amount or nature of the Merger Consideration
or relieve the assigning party of its obligations hereunder if such assignee
does not perform such obligations.

     SECTION 9.07. Parties in Interest. This Agreement shall be binding upon and
inure solely to the benefit of each party hereto, and nothing in this Agreement,
express or implied, is intended to or shall confer upon any other person any
right, benefit or remedy of any nature whatsoever under or by reason of this
Agreement, other than Sections 6.06 and 6.11 (which are intended to be for the
benefit of the persons covered thereby and may be enforced by such persons).

     SECTION 9.08. Specific Performance. The parties hereto agree that
irreparable damage would occur in the event any provision of this Agreement was
not performed in accordance with the terms hereof and that the parties shall be
entitled to specific performance of the terms hereof, in addition to any other
remedy at law or in equity.

     SECTION 9.09. Governing Law. This Agreement shall be governed by, and
construed in accordance with, the laws of the State of Florida applicable to
contracts executed in and to be performed in that state.

     SECTION 9.10. Headings. The descriptive headings contained in this
Agreement are included for convenience of reference only and shall not affect in
any way the meaning or interpretation of this Agreement.

     SECTION 9.11. Counterparts. This Agreement may be executed and delivered
(including by facsimile transmission) in one or more counterparts, and by the
different parties hereto in separate counterparts, each of which when executed
and delivered shall be deemed to be an original but all of which taken together
shall constitute one and the same agreement.




<PAGE>



     IN WITNESS WHEREOF, Parent, Merger Sub and the Company have caused this
Agreement to be executed as of the date first written above by their respective
officers thereunto duly authorized.

                               ELAN CORPORATION, PLC.


                               By:   /s/ Thomas G. Lynch
                                     -------------------------------------
                                     Name:  Thomas G. Lynch
                                     Title: Executive Vice President and
                                            Chief Financial Officer


                               EVERGLADE ACQUISITION CORP.


                               By:   /s/ Thomas G. Lynch
                                     -------------------------------------
                                     Name:   Thomas G. Lynch
                                     Title:  Executive Vice President and
                                             Chief Financial Officer


                               SANO CORPORATION


                               By:   /s/ Marc M. Watson
                                     -------------------------------------
                                     Name:   Marc M. Watson
                                     Title:  Chairman of the Board












                                VOTING AGREEMENT

     VOTING AGREEMENT, dated as of December 14, 1997 (this "Agreement"), among
ELAN CORPORATION, PLC, a public limited company organized under the laws of
Ireland ("Purchaser") and the individuals whose names and addresses are set
forth on the signature pages hereto (collectively, the "Stockholders", and each,
individually, a "Stockholder").

     WHEREAS, Purchaser and its wholly owned subsidiary, Everglade Acquisition
Corp., a Delaware corporation (the "Subsidiary"), have entered into an Agreement
and Plan of Merger, dated as of the date hereof (the "Merger Agreement"), with
Sano Corporation, a Florida corporation (the "Company"), which Merger Agreement
provides, among other things, that the Subsidiary will merge with and into the
Company pursuant to the merger contemplated by the Merger Agreement (the
"Merger"); and

     WHEREAS, as of the date hereof, the Stockholders own (both beneficially and
of record) the number of shares of Common Stock, par value $.01 per share, of
the Company ("Company Common Stock") set forth opposite their respective names
at the foot of this Agreement; and

     WHEREAS, the Stockholders have agreed to enter into this Agreement
governing the voting and disposition of the shares of Company Common Stock now
owned and which may hereafter be acquired by any of the Stockholders (the
"Shares").

     NOW, THEREFORE, in consideration of the foregoing and the mutual covenants
and agreements contained herein, and intending to be legally bound hereby, the
parties hereto hereby agree as follows:

     1. Voting of Shares. Each Stockholder shall, until the Termination Date (as
hereinafter defined), cause the Shares owned by such Stockholder to be voted at
any meeting of the Stockholders of the Company or in any consent in lieu of such
a meeting in favor of the Merger Agreement and the transactions contemplated
thereby, subject to his obligation to faithfully discharge his duty as a
director of the Company, provided that the Merger Agreement shall not have been
amended to adversely affect the Stockholders in any material respect, without
the consent of the Stockholders. For the purposes of this Agreement,
"Termination Date" shall mean the earliest of (i) the termination of the Merger
Agreement in accordance with its terms, (ii) the Effective Time (as defined in
the Merger Agreement), (iii) the termination of this Agreement by the mutual

<PAGE>
                                      -2-


written agreement of the parties hereto or pursuant to the terms of Section 8 of
this Agreement.

     2. Irrevocable Proxy. Each Stockholder hereby irrevocably appoints
Purchaser, subject to his obligation to faithfully discharge his duty as a
director of the Company, until the Termination Date, as its attorney and proxy
pursuant to the provisions of Section 607.0722 of the Florida Business
Corporation Act with full power of substitution, to vote in such manner as
Purchaser or its substitute shall, in its sole discretion, deem proper and
otherwise act (by written consent or otherwise) with respect to the Shares (and
all other securities issued to the Stockholder in respect of the Shares) which
each Stockholder is entitled to vote at any meeting of Stockholders of the
Company (whether annual or special and whether or to an adjourned or postponed
meeting) or in respect of any consent in lieu of any such meeting or otherwise
in accordance with the provisions of Section 1 of this Agreement. This proxy and
power of attorney is irrevocable and coupled with an interest in favor of
Purchaser. Each Stockholder hereby revokes all other proxies and powers of
attorney with respect to the Shares (and all other securities issued to the
Stockholder in respect of the Shares) which it may have heretofore appointed or
granted, and no subsequent proxy or power of attorney shall be given or written
consent executed (and if given or executed, shall not be effective) by the
Stockholder with respect thereto.

     3. No Disposition or Encumbrance of Shares. Each Stockholder hereby
covenants and agrees that, except as contemplated by this Agreement, the
Stockholder shall not, and shall not offer or agree to, sell, transfer, tender,
assign, hypothecate or otherwise dispose of, or create or permit to exist any
security interest, lien, claim, pledge, option, right of first refusal,
agreement, limitation on the Stockholder's voting rights, charge or other
encumbrance of any nature whatsoever with respect o the shares.

     4. No Solicitation of Transactions. Except with respect to activities as a
director of the Company, each Stockholder shall not, directly or indirectly,
through any agent or representative or otherwise, (i) solicit, initiate,
facilitate or encourage (including by way of furnishing or disclosing non-public
information) any inquiries or the making of any proposal with respect to any
merger, consolidation or other business combination involving the Company or
acquisition of any kind of material portion of the assets or capital stock of
the Company (an "Acquisition Transaction") or negotiate, explore or otherwise
communicate in any way with any third party with respect 


<PAGE>
                                      -3-


to any Acquisition Transaction or enter into any agreement, arrangement or
understanding requiring it to abandon, terminate or fail to perform as
contemplated by this Agreement. Each Stockholder immediately shall cease and
cause to be terminated all existing discussions or negotiations of the
Stockholder and its agents or other representatives with any Person conducted
heretofore with respect to any of the foregoing. Each Stockholder shall notify
immediately Purchaser if any proposal or offer, or any inquiry or contact with
any Person with respect to an Acquisition Transaction, is made and shall, in any
such notice to Purchaser, indicate in reasonable detail the identity of the
Person making such proposal, offer, inquiry or contact and the terms and
conditions of such proposal, offer, inquiry or contact. The provisions of this
Section 4 shall not apply to or restrict any action that may be taken by any
Stockholder in his capacity as a director of the Company.

     5. Legend on Certificates. The certificate(s) evidencing the Shares shall
be endorsed with a restrictive legend substantially as follows:

          THE SHARES EVIDENCED BY THIS CERTIFICATE ARE SUBJECT TO A VOTING
          AGREEMENT DATED AS OF DECEMBER 14, 1997 BETWEEN THE REGISTERED HOLDER
          HEREOF AND ELAN CORPORATION, PLC, A COPY OF WHICH IS ON FILE AT THE
          PRINCIPAL OFFICE OF THE COMPANY. THE HOLDER OF THIS CERTIFICATE, BY
          HIS ACCEPTANCE HEREOF, AGREES TO BE BOUND BY ALL THE TERMS OF SUCH
          AGREEMENT, AS THE SAME IS IN EFFECT FROM TIME TO TIME.

     6. Representations and Warranties of the Stockholders. Each Stockholder
hereby severally represents and warrants with respect to itself and its
ownership of the Shares to Purchaser as follows:

     a. Authority Relative to this Agreement. The Stockholder has all necessary
power and authority to execute and deliver this Agreement, to perform its
obligations hereunder and to consummate the transactions contemplated hereby.
The execution and delivery of this Agreement by the Stockholder and the
consummation by the Stockholder of the transactions contemplated hereby have
been duly and validly authorized by all necessary action on the part of the
Stockholder. This Agreement has been duly and validly executed and delivered by
the Stockholder and, assuming the due authorization, execution and delivery by
Purchaser, constitutes a legal, valid and binding obligation of the Stockholder,
enforceable against the Stockholder in accordance with its terms, except that
such en-


<PAGE>
                                      -4-


forceability may be limited by bankruptcy, insolvency or similar laws affecting
creditors' rights generally.

     b. No Conflict. The execution and delivery of this Agreement by the
Stockholder does not, and the performance of this Agreement by the Stockholder
will not, (i) require any consent, approval, authorization or permit of, or
filing with or notification to (other than pursuant to the HSR Act and the
Securities Exchange Act of 1934, as amended), any governmental or regulatory
authority, domestic or foreign, (ii) conflict with or violate the Certificate of
Incorporation or By-laws of the Stockholder, (iii) conflict with or violate any
law, rule, regulation, order, judgment or decree applicable to the Stockholder
or by which any property or asset of the Stockholder is bound, or (iv) result in
any breach of or constitute a default (or an event which with notice or lapse of
time or both would become a default) under, or give to others any right of
termination, amendment, acceleration or cancellation of, or result in the
creation of a lien or other encumbrance of any nature whatsoever on any property
or asset of the Stockholder pursuant to, any note, bond, mortgage, indenture,
contract, agreement, lease, license, permit, franchise or other instrument or
obligation to which the Stockholder is a party or by which the Stockholder or
any property or asset of the Stockholder is bound.

     c. Title to the Shares. The Shares owned by the Stockholder are all the
securities of the Company owned, either of record or beneficially, by the
Stockholder. The Stockholder owns all such Shares free and clear of all security
interests, liens, claims, pledges, options, rights of first refusal, agreements,
limitations on the Stockholder's voting rights, charges and other encumbrances
of any nature whatsoever, and, except as provided in this Agreement, the
Stockholder has not appointed or granted any proxy, which appointment or grant
is still effective, with respect to the Shares.

     d. Brokers. No broker, finder or investment banker is entitled to any
brokerage, finder's or other fee or commission in connection with the
transactions contemplated hereby based upon arrangements made by or on behalf of
the Stockholder.

     7. Representations and Warranties of Purchaser. Purchaser hereby represents
and warrants to the Stockholders that Purchaser has all necessary power and
authority to execute and deliver this Agreement and to perform its obligations
hereunder. The execution, delivery and performance of this Agreement by
Purchaser have been duly authorized by all necessary 


<PAGE>
                                      -5-


action on the part of Purchaser. This Agreement has been duly and validly
executed and delivered by Purchaser and, assuming the due authorization,
execution and delivery by the Stockholders, constitutes a legal, valid and
binding obligation of Purchaser enforceable in accordance with its terms, except
that such enforceability may be limited by bankruptcy, insolvency or similar
laws affecting creditors' rights generally.

     8. Termination of Agreement.Purchaser reserves the right in its sole
discretion at any time hereafter to terminate this Agreement and all irrevocable
proxies granted to it hereunder.

     9. Miscellaneous.

     a. Expenses. Except as otherwise provided herein or in the Merger
Agreement, all costs and expenses incurred in connection with the transactions
contemplated by this Agreement shall be paid by the party incurring such
expenses.

     b. Further Assurances. From time to time at the other party's reasonable
request, Purchaser and the Stockholders will execute and deliver all such
further documents and instruments and take all such further action as may be
necessary in order to consummate the transactions contemplated hereby.

     c. Specific Performance. The parties hereto agree that irreparable damage
would occur in the event any of the provisions of this Agreement were not
performed in accordance with the terms hereof and that the parties shall be
entitled to specific performance of the terms hereof, in addition to any other
remedy to which they may be entitled at law or in equity.

     d. Entire Agreement. This Agreement constitutes the entire agreement
between Purchaser and the Stockholders with respect to the subject matter hereof
and supersedes all prior agreements and understandings, both written and oral,
between Purchaser and the Stockholders with respect to the subject matter
hereof.

     e. Assignment. This Agreement shall not be assigned by operation of law or
otherwise, without the prior written consent of the parties.

     f. Obligations of Successors; Parties in Interest. This Agreement shall be
binding upon, inure solely to the benefit of, and be enforceable by, the
successors and permitted assigns of the parties hereto. Nothing in this
Agreement, ex-


<PAGE>
                                      -6-


press or implied, is intended to or shall confer upon any other person any
rights, benefits or remedies of any nature whatsoever under or by reason of this
Agreement.

     g. Amendment; Waiver. This Agreement may not be amended or changed except
by an instrument in writing signed by the parties hereto. Any party hereto may
(i) extend the time for the performance of any obligation or other act of the
other party hereto, (ii) waive any inaccuracy in the representations and
warranties contained herein or in any document delivered pursuant hereto and
(iii) waive compliance with any agreement or condition contained herein. Any
such extension or waiver shall be valid if set forth in an instrument in writing
signed by the party or parties to be bound thereby.

     h. Severability. The validity or unenforceability of any provision of this
Agreement shall not affect the validity or enforceability of any other provision
of this Agreement, which shall remain in full force and effect.

     i. Notices. All notices, requests, claims, demands and other communications
hereunder shall be in writing and shall be given (and shall be deemed to have
been duly given upon receipt) by delivery in person, by cable, telecopy,
telegram or telex or by registered or certified mail (postage prepaid, return
receipt requested) to the respective parties at the following addresses (or at
such other address for a party as shall be specified in a notice given in
accordance with this Section 8(i):

                  if to Purchaser:

                           Elan Corporation, plc
                           Lincoln House
                           Lincoln Place
                           Dublin 2
                           Ireland
                           Attention:  Thomas G. Lynch
                           Telecopy:  011-353-1-662-4963


<PAGE>
                                      -7-


                  with a copy to:

                           Cahill Gordon & Reindel
                           80 Pine Street
                           New York, New York 10005
                           Attention: William Hartnett.
                           Telecopy:        (212) 269-5420

                  if to any Stockholder:

                           at the respective addresses of such Stockholder
                           set forth on the signature pages to this Agreement.

     j. Governing Law. THIS AGREEMENT SHALL BE GOVERNED BY, AND CONSTRUED IN
ACCORDANCE WITH, THE LAWS OF THE STATE OF FLORIDA APPLICABLE TO CONTRACTS
EXECUTED IN AND TO BE PERFORMED IN THAT STATE.

     k. Headings. The descriptive headings contained in this Agreement are
included for convenience of reference only and shall not affect in any way the
meaning or interpretation of this Agreement.

     l. Parties in Interest. This Agreement shall be binding upon and inure
solely to the benefit of each party hereto, and nothing in this Agreement,
express or implied, is intended to or shall confer upon any other person any
rights, benefits or remedies or any nature whatsoever under or by reason of this
Agreement.

     m. Counterparts. This Agreement may be executed in one or more
counterparts, and by the different parties hereto in separate counterparts, each
of which when executed shall be deemed to be an original but all of which taken
together shall constitute one and the same agreement.

     n. WAIVER OF JURY TRIAL. EACH PARTY HERETO WAIVES ANY RIGHT IT MIGHT HAVE
TO A JURY TRIAL OF ANY DISPUTE ARISING IN CONNECTION WITH THIS AGREEMENT.








<PAGE>
                                      -8-


     IN WITNESS WHEREOF, Purchaser and the Stockholders have duly executed this
Agreement, as of the date first written above.

PURCHASER:

ELAN CORPORATION, PLC

By: /s/  Thomas G. Lynch
    -------------------------------
       Name:  Thomas G. Lynch
       Title: Director

STOCKHOLDERS:                                   NUMBER OF SHARES OWNED:



/s/  Reginald Hardy
    -------------------------------
    Name:  Reginald Hardy
    Address:  2780 Egret Way
              Cooper City, FL  33026




/s/  Marc Watson
    -------------------------------
    Name:  Marc Watson
    Address:  6126 S.W. 152 Street
              Miami, FL  33157







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