ELAN CORP PLC
425, 2000-09-12
PHARMACEUTICAL PREPARATIONS
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                                             Filed by Dura Pharmaceuticals, Inc.
                                                  Pursuant to Rule 425 under the
                                         Securities Act of 1933 and deemed filed
                                                         pursuant to Rule 14a-12
                                          Subject Company: Elan Corporation, plc
                                                        Commission No. 333-10726


                              FOR IMMEDIATE RELEASE

<TABLE>
<CAPTION>

CONTACTS:
INVESTORS:  (U.S.)                          INVESTORS:  (EUROPE)                MEDIA:
<S>                                         <C>                                 <C>
Jack Howarth/Mary Ansaldi                   Emer Reynolds                       Max Gershenoff
Elan Corporation, plc                       Elan Corporation, plc               Elan Corporation, plc
Ph:  212-407-5740                           Ph:  353-1-709-4000                 Ph:  212-407-5740
     800-252-3526                                00800 28352600                      800-252-3526

Mike Borer/Julie Bierle
Dura Pharmaceuticals, Inc.
Ph:  858-457-2553
</TABLE>


                              ELAN TO ACQUIRE DURA
     -- hCQUISITION SIGNIFICANTLY STRENGTHENS ELAN'S PHARMACEUTICAL BUSINESS --
        -- ADDS OVER 500 SALES REPRESENTATIVES AND $300 MILLION IN REVENUE --
           -- TRANSACTION TO BE ACCRETIVE TO EARNINGS PER SHARE IN 2001 --

DUBLIN, IRELAND/SAN DIEGO, CALIFORNIA, SEPTEMBER 11, 2000 -- Elan Corporation,
plc (NYSE: ELN) ("Elan") and Dura Pharmaceuticals, Inc. (NASDAQ: DURA) ("Dura")
today announced that they have entered into a definitive merger agreement under
which Elan will acquire Dura, a specialty pharmaceutical company engaged in the
marketing and sale of prescription products for the treatment of infectious
diseases and respiratory conditions. The Dura Board of Directors has unanimously
approved the merger agreement and is recommending that the Dura stockholders
approve the merger.

Under the terms of the merger agreement, Elan will acquire all of Dura's
outstanding common stock in a tax-free, stock for stock transaction, which will
be accounted for using

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the pooling-of-interests method. Elan expects the transaction to be accretive to
earnings per share in 2001 after synergies. Dura stockholders will receive
0.6715 of an Elan ADS for each share of Dura common stock. Based on Elan's
closing stock price on September 8, 2000 of $52.125, the transaction has a value
of $35.00 per Dura share and a total transaction value of approximately $1.8
billion.

Donal Geaney, Chairman and Chief Executive Officer of Elan, commented, "This
transaction significantly enhances Elan's North American Pharmaceutical business
by doubling the size of our U.S. salesforce to over 1,000 sales representatives
and adding over $300 million of sales revenue in 2001 driven primarily by four
key products. As a result of this transaction, we will have a much stronger
sales and marketing infrastructure, a broader portfolio of marketed products and
additional strength in our management team. The combined salesforce and
management team will help us launch and maximize the revenue potential of our
near-term product pipeline. In addition, I am pleased that we can add the
Spiros-Registered Trademark- platforms to our range of drug delivery
technologies."

Cam Garner, Chairman and Chief Executive Officer of Dura, said, "I am proud that
the combination of Dura and Elan creates a substantial enterprise poised to
quickly become a major global player in the pharmaceutical industry. The
transaction represents both great financial and strategic value for our
shareholders and our associates. The Elan management team is well known to Dura.
They exhibit an entrepreneurial spirit and the desire to establish an
extraordinary company culture uncommon in most large pharmaceutical companies."

Dura's portfolio of specialty pharmaceutical products includes
Maxipime-Registered Trademark-(injectable cephalosporin antibiotic),
Ceclor-Registered Trademrk- CD (oral cephalosporin antibiotic),
Azactam-Registered Trademark- (injectable monobactum antibiotic) and
Nasarel-Registered Trademark- (inhaled corticosteroid). Dura supports these
products with large and experienced hospital and primary care salesforces,
numbering over 500 representatives.

<PAGE>

The transaction, which has been unanimously approved by the Board of Directors
of both companies, is subject to regulatory approvals, approval by Dura
stockholders and customary closing conditions and is expected to close late in
the fourth quarter of this year.

Elan is a leading worldwide specialty pharmaceutical and drug delivery company
headquartered in Ireland, with its principal research, development,
manufacturing and marketing facilities located in Ireland, the United States and
Israel. Elan is focused on the discovery, development and marketing of
therapeutic products and services in neurology, pain management and oncology,
and on the development and commercialization of products using its extensive
range of proprietary drug delivery technologies. Elan shares trade on the New
York, London and Dublin Stock Exchanges.

Dura is a San Diego based specialty pharmaceutical company that markets and
sells prescription products that treat infectious diseases and respiratory
conditions. Dura focuses on products and transactions that leverage its sales
and marketing organization. Also, through the use of collaborative
relationships, Dura intends to develop the Spiros-Registered
Trademark-blisterdisk and Spiros-Registered Trademark- S2 pulmonary drug
delivery systems for the local and systemic delivery of a wide range of
medications.

This communication may include certain  "forward-looking  statements" within the
meaning  of  the  Private  Securities  Litigation  Reform  Act  of  1995.  These
statements  are based on  management's  current  expectations  and are naturally
subject to  uncertainty  and changes in  circumstances.  Actual results may vary
materially  from  the  expectations   contained  herein.   The   forward-looking
statements in this  communication  include statements about future financial and
operating results and the proposed merger. The following factors,  among others,
could cause actual results to differ  materially  from those  described  herein:
inability to obtain, or meet conditions imposed for, governmental  approvals for
the merger;  failure of the Dura  stockholders  to approve the merger;  the risk
that the Elan and Dura businesses will not be integrated successfully; the costs
related  to  the  merger;  and  other  economic,  business,  competitive  and/or
regulatory  factors  affecting  Elan's and  Dura's  businesses  generally.  More
detailed  information  about  these  factors  is set forth in Elan's  and Dura's
filings with the Securities and Exchange  Commission  ("SEC"),  including Elan's
Annual  Report on Form 20-F and Dura's  Annual Report on Form 10-K, in each case
for the fiscal year ended  December 31,  1999,  especially  in the  Management's
Discussion and Analysis sections thereof.  Elan and Dura are under no obligation
to  (and   expressly   disclaim  any   obligation  to)  update  or  alter  these
forward-looking  statements,  whether  as a result  of new  information,  future
events or otherwise.

<PAGE>

In connection with the transaction, Elan will file a registration statement on
Form F-4 and Dura will file a proxy statement, each with the SEC. Investors and
security holders are advised to read the registration statement and the proxy
statement when they become available because they will contain important
information. Investors and security holders may obtain a free copy of the proxy
statement (when available) and other documents filed by Dura with the SEC at the
SEC's web site at http://www.sec.gov. Free copies of the registration statement
(when available) and other documents filed by Elan with the SEC may be obtained
from Elan by directing a request to Elan, 345 Park Avenue, New York, New York
10154, attention: Jack Howarth, (212-407-5740). Free copies of the proxy
statement and the other documents filed by Dura with the SEC may also be
obtained from Dura by directing a request to Dura Pharmaceuticals, Inc., 7475
Lusk Blvd., San Diego, CA 92121, attention: Corporate Secretary, (858-457-2553).

Dura, its directors, executive officers and certain other members of its
management and employees may be deemed to be participants in the solicitations
of proxies of Dura's stockholders to adopt the merger agreement providing for
Elan's acquisition of Dura. These persons may have an interest in the
transaction, including as a result of holding shares or options of Dura. A
detailed list of the names and interests of Dura's directors and executive
officers is contained in Dura's proxy statement for its 2000 Annual Meeting,
which may be obtained without charge at the SEC's web site at
http://www.sec.gov.

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