MEDTOX SCIENTIFIC INC
DEF 14A, 1999-08-09
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                            SCHEDULE 14A INFORMATION

Proxy StatementPursuant to Section 14(a) of the Securities Exchange Act of 1934
                                (Amendment No. )

Filed by the Registrant  [X]
Filed by a Party other than the Registrant [  ]

Check the appropriate box:


[ ]      Preliminary Proxy Statement
[ ]      Confidential,  for  Use  of the  Commission  Only  (as  permitted  by
         Rule 14a-6(e)(2))
[X]      Definitive Proxy Statement
[ ]      Definitive Additional Materials
[ ]      Soliciting Material Pursuant to Section 240.14a-11(c) or Section 240.
         14a-12


                             MEDTOX SCIENTIFIC, Inc.
                (Name of Registrant as Specified In Its Charter)

                    (Name of Person(s) Filing Proxy Statement
                          if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):


[  ]     $125 per Exchange Act Rules 0-11(c)(1)(ii), 14a-6(i)(2).
[  ]     $500 per each party to the controversy pursuant to Exchange Act Rule
         14a-6(i)(3).
[  ]     Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and
         0-11.
         1)    Title of each class of securities to which transaction applies:
         2)    Aggregate number of securities to which transaction applies:
         3)    Per unit price or other  underlying  value of  transaction
               computed  pursuant to Exchange Act Rule 0-11;1
         4)    Proposed maximum aggregate value of transaction:
               1  Set forth  the  amount  on which  the  filing  fee is
               calculated and state how it was determined.
[X ]     Fee Paid Previously with preliminary materials.
[  ]     Check box if any part of the fee is offset as  provided  by  Exchange
         Act Rule  0-11(a)(2)  and identify the filing for which the  offsetting
         fee was paid  previously.  Identify the previous filing by registration
         statement number, or the Form or Schedule and the date of its filing.
         1)       Amount Previously Paid:
         2)       Form, Schedule or Registration Statement No:
         3)       Filing Party:
         4)       Date Filed:



<PAGE>




                             MEDTOX SCIENTIFIC, INC.
                             402 West County Road D
                            St. Paul, Minnesota 55112


                           NOTICE OF ANNUAL MEETING OF
                    STOCKHOLDERS To Be Held on September 16, 1999

         NOTICE IS HEREBY  GIVEN  that the Annual  Meeting  of the  stockholders
("Annual  Meeting")  of MEDTOX  SCIENTIFIC,  INC., a Delaware  corporation  (the
"Company"), will be held at the Sheraton Minneapolis Metrodome,  located at 1330
Industrial Blvd., Minneapolis, Minnesota on Thursday, September 16, 1999 at 2:00
p.m. (CST) for the following purposes:

1.   To elect five  directors  to serve on the Board of Directors of the Company
     (the "Board of Directors") for the ensuing year; and

2.   To consider  and act upon a proposal to ratify and approve an  amendment to
     Article FOURTH of the Company's  Certificate of  Incorporation  to increase
     its number of authorized  common stock from  3,750,000  shares to 7,400,000
     shares; and

3.   To consider  and act upon a proposal to ratify and approve an  amendment to
     Article FIFTH of the Company's  Certificate of Incorporation to provide for
     the  classification  of the  Board  of  Directors  into  three  classes  of
     directors with staggered terms of office; and

4.   To consider  and act upon an  amendment  to the  Company's  Employee  Stock
     Purchase  Plan to  increase  from  25,000 to  150,000  the number of shares
     authorized to be issued pursuant to that Plan; and

5.   To consider and act upon any other  matters  which may properly come before
     the meeting or any adjournment thereof.

         In accordance  with the  provisions  of the Bylaws of the Company,  the
Board of  Directors  has fixed the  close of  business  on August 1, 1999 as the
record date for the  determination  of the holders of the shares of Common Stock
entitled to notice of, and to vote at, the Annual Meeting.

         Your attention is directed to the accompanying Proxy Statement.

         Stockholders are requested to date, sign and mail the enclosed Proxy as
promptly  as  possible,  whether  or not they  expect to attend  the  meeting in
person.

                                        By Order of the Board of  Directors,


                                        Harry G. McCoy
                                        Chairman of the Board and President


St. Paul, Minnesota
August 9, 1999



<PAGE>

                             MEDTOX SCIENTIFIC INC.
                             402 West County Road D
                            St. Paul, Minnesota 55112


                                PROXY STATEMENT


                         ANNUAL MEETING OF STOCKHOLDERS
                               September 16, 1999

                                     PROXIES

         The enclosed  proxy (the  "Proxy") is solicited by and on behalf of the
Board of  Directors of MEDTOX  SCIENTIFIC,  INC.,  a Delaware  corporation  (the
"Company"),  for use at the Company's 1998 annual meeting of  stockholders  (the
"Annual Meeting") and at any and all adjournments  thereof.  Any stockholder has
the power to revoke his or her Proxy at any time before it is voted. A Proxy may
be revoked (1) by delivery of written  notice of  revocation to the Secretary of
the Company at its principal office, 402 West County Road D, St. Paul, Minnesota
55112,  (2) by the  execution  of a  subsequent  Proxy and  presentment  of such
subsequent  Proxy at the  Annual  Meeting  or (3) by  attendance  at the  Annual
Meeting  and voting in  person.  This  solicitation  is being made by use of the
mails and the cost thereof will be borne by the Company.  Shares  represented by
valid  Proxies  will be voted in  accordance  with  the  instructions  indicated
thereon.  Unless otherwise directed,  votes will be cast FOR the election of the
directors named and FOR Proposals 2, 3 and 4.

         The costs of solicitation  of proxies will be borne by the Company.  In
addition to use of mails, proxies may be solicited  personally,  or by telephone
by one or  more of the  regular  personnel  of the  Company  without  additional
compensation.  The  Company  expects  to  pay  an  independent  proxy  solicitor
approximately  $15,000 as  compensation  for the  solicitation  of  proxies.  In
addition,  the Company may reimburse brokers and other custodians,  nominees and
fiduciaries for their expenses for sending proxy material to beneficial  owners,
in accordance with Securities and Exchange Commission regulations.

         The Company  anticipates  mailing proxy materials and the annual report
for  its  fiscal  year  ended  December  31,  1998  (the  "Annual   Report")  to
stockholders  of record as of  August 1, 1999 (the  "Stockholders")  on or about
August 9, 1999.

<PAGE>
                            OUTSTANDING VOTING STOCK


         Only holders of record of the Company's  Common  Stock,  par value $.15
per share (the "Common  Stock"),  at the close of business on August 1, 1999 are
entitled to vote on matters to be presented at the Annual Meeting. Each share of
Common  Stock is  entitled  to one vote with  respect to all such  matters.  The
number of shares of Common Stock  outstanding  and entitled to vote at the close
of business on August 1, 1999 was 2,903,222.


                          VOTE AND QUORUM REQUIREMENTS

         The presence in person or by Proxy of Stockholders of a majority of the
outstanding  shares of Common  Stock is  required  for there to exist the quorum
needed to  transact  business at the Annual  Meeting.  If,  initially,  a quorum
should not be present,  the Annual  Meeting may be  adjourned  from time to time
until a quorum is obtained.

         A plurality of the votes cast is required to elect the  Directors.  The
affirmative  vote of a majority  of the  outstanding  shares of common  stock is
required  for  approval  of  the  proposed  amendments  to  the  Certificate  of
Incorporation  of the Company.  In the election of  Directors,  any action other
than a vote for a nominee will have the practical  effect of voting  against the
nominee.  Abstentions and "broker  non-votes" (as defined below) are counted for
purposes of determining whether a quorum is present,  but do not represent votes
cast with  respect to any  proposal.  "Broker  non-votes"  are shares  held by a
broker or nominee for which an executed  proxy is received by the  Company,  but
are not voted as to one or more  proposals  because  instructions  have not been
received from the beneficial  owners or persons  entitled to vote and the broker
or nominee does not have discretionary voting power.

         An independent party will receive and tabulate all proxies and ballots,
and such  independent  party and certain  other team members of the Company will
act as voting inspectors at the Annual Meeting.

<PAGE>
                        COMMON STOCK OWNERSHIP OF CERTAIN
                        BENEFICIAL OWNERS AND MANAGEMENT

         The following table sets forth information  available to the Company as
of July 20, 1999 regarding the  beneficial  ownership of the Common Stock by (i)
each person known by the Company to beneficially own more than Five Percent (5%)
of the  outstanding  Common  Stock,  (ii) each of the Directors and nominees for
Director of the Company,  (iii) the Chief  Executive  Officer and all  executive
officers  whose  compensation  was $100,000 or greater during 1998, and (iv) all
executive  officers,  Directors  and nominees for  Directors of the Company as a
group:

<TABLE>
<CAPTION>

                                                                       Number of Shares            Percent of Common
  Name                                                               Beneficially Owned            Stock Outstanding

 <S>                                                                <C>                           <C>
  Executive Officers and Directors:
  Harry G. McCoy, Pharm. D.
    Chairman and President                                                  212,619 (1)                       6.70 %
  Richard J. Braun
    Chief Executive Officer and Director                                     70,178 (2)                       2.31 %
  Samuel C. Powell, Ph.D., Director                                          73,241 (3)                       2.41 %
  James W. Hansen, Director                                                   6,863 (4)                            *
  Miles E. Efron, Director                                                    5,358 (5)                            *
  Kevin J. Wiersma
    Vice President, Controller and Secretary                                  6,246 (6)                            *
  All Directors and Executive Officers
    as a Group (6 in number)                                                374,505 (7)                      12.32 %
</TABLE>


*        Less than one percent (1%)

1.   Includes  54,271 shares of Common Stock issuable under options which are or
     which will become exercisable within the next 60 days.

2.   Includes  63,928 shares of Common Stock issuable under options which are or
     which will become exercisable within the next 60 days.

3.   Includes  4,994 shares of Common Stock  issuable under options which are or
     will become exercisable within the next 60 days.

4.   Includes  4,363 shares of Common Stock  issuable under options which are or
     which will become exercisable within the next 60 days.

5.   Includes  2,858 shares of Common Stock  issuable under options which are or
     which will become exercisable within the next 60 days.

6.   Includes  6,046 shares of Common Stock  issuable under options which are or
     which will become exercisable within the next 60 days.

7.   Includes 136,460 shares of Common Stock issuable under options which are or
     will become exercisable within the next 60 days.
<PAGE>

                                   PROPOSAL 1
                              ELECTION OF DIRECTORS

         The Certificate of  Incorporation  provides that the Board of Directors
shall consist of not less than three nor more than twelve individuals,  with the
exact number to be fixed from time to time by the majority  vote of the Board of
Directors.  The Board of  Directors  has fixed the number of  Directors  at five
individuals.

         The Board of  Directors  intends  to  present  for action at the Annual
Meeting the  election  of Harry G. McCoy,  Pharm.D.,  Samuel C.  Powell,  Ph.D.,
Richard J.  Braun,  James W.  Hansen and Miles E. Efron to serve for the ensuing
year and until their  respective  successors  are duly  elected  and  qualified.
Unless otherwise  instructed,  the enclosed Proxy will be voted FOR the election
of the nominees  listed  below,  except that the persons  designated  as proxies
reserve full  discretion to cast their votes for another  person  recommended by
the Board of Directors in the unanticipated  event that any nominee is unable or
declines to serve.

         Directors  will be  elected  by the  plurality  vote of the  holders of
Common Stock  entitled to vote at the Annual Meeting and present in person or by
Proxy.

         The following  table sets forth the name, age and the position with the
Company of the nominees for Directors:

                                 Director
Name of Nominee            Age   Since    Class*      Position with the Company
- ---------------            ---   -----    -----       -------------------------

Harry G. McCoy, Pharm. D.  48    1996     III          Chairman of the Board of
                                                        Directors and President
Samuel C. Powell, Ph.D.    47    1986       I          Director
Richard J. Braun           54    1996     III          Chief Executive Officer
                                                        and Director
James W. Hansen            44    1996      II          Director
Miles E. Efron             72    1997       I          Director
- --------
* Class  designations  are contingent upon approval of Proposal 3 establishing a
classified Board of Directors.

    Harry G. McCoy, Pharm.D., was elected Chairman of the Board of Directors and
President  in July 1996 and has served as a Director  since  January  1996.  Dr.
McCoy founded MEDTOX in 1984, and served as both Clinical Director and member of
the MEDTOX Board of Directors  until its  acquisition  by the Company in January
1996. Dr. McCoy  continued as President of MEDTOX  following its  acquisition by
the Company.  Dr. McCoy also has academic  appointments  with the  University of
Minnesota and the  University  of North  Dakota,  and is Chairman and CEO of the
Nova Jazz Corporation, a Minnesota non-profit company.

         Richard J. Braun was named as a Director and elected as Chief Executive
Officer in July 1996. From 1994 until joining the Company,  Mr. Braun acted as a

<PAGE>

private investor and provided management  consulting services to the health care
and  technology  industries.  From 1992 until 1994,  Mr.  Braun  served as Chief
Operating  Officer and as a Director of EBP,  Inc.,  a NYSE  company  engaged in
managed  care.  From 1989 through  1991,  Mr.  Braun  served as  Executive  Vice
President,  Chief Operating  Officer and Director of Reich and Tang L.P., a NYSE
investment advisory and broker dealer firm. Mr. Braun currently is a Director of
Enstar,  Inc.,  a public  company with  investments  in health care and computer
connectivity and networking.

         Samuel C. Powell,  Ph.D.,  served as Chairman of the Board of Directors
from  November  1987 to June 1994 and has  served as a Director  of the  Company
since  September  1986.  Dr.  Powell  served as  Chairman of the Board and Chief
Executive Officer of Granite Technological Enterprises,  from January 1984 until
its  acquisition by the Company in June 1986.  Since 1987, he has been President
of Powell  Enterprises,  Burlington,  North  Carolina,  offering  financial  and
management  services  to a  variety  of  businesses  and real  estate  ventures.

         James W. Hansen was named as a Director in September  1996.  Mr. Hansen
has, since November 1996, been Chairman, CEO and Treasurer of Videolabs, Inc., a
NASDAQ traded,  technology company and is CEO of Prevention First, a development
stage medical services  provider.  From 1986 to 1992, Mr. Hansen was Senior Vice
President  and General  Manager of the Pension  Division  of  Washington  Square
Capital,  a Reliastar company which is a NYSE traded financial services company.
Since 1992,  Mr. Hansen has served as an Investor,  Director,  President or Vice
President of several private  companies in medical  services and technology.  He
also serves as a Director of UBIQ,  Inc.,  Videolabs,  Inc. and Prevention First
and has taught in the MBA program at the University of St.
Thomas since 1984.

     Miles E. Efron was named as a Director in January 1997.  From 1988 to 1993,
Mr. Efron served as Chief Executive  Officer of North Star Universal,  a holding
company with interests in health care,  food products and computer  connectivity
and  networking.  Since  1993,  Mr.  Efron has served as  Chairman of North Star
Universal.  Mr.  Efron  currently  serves on the Board of  Directors  of several
companies, none of which are related to the Company.

Compliance With Section 16(a) Of The Securities Exchange Act of 1934

         Section  16(a) of the  Securities  Exchange  Act of 1934,  as  amended,
requires that the Company's  directors and executive  officers,  and persons who
own more than ten percent (10%) of a registered  class of the  Company's  equity
securities, file with the Commission initial reports of ownership and reports of
changes in ownership of Common Stock and other equity securities of the Company.
Officers,  directors and greater than ten percent beneficial owners are required
by Commission regulations to furnish the Company with copies of all reports they
file under Section 16(a).

         To the Company's knowledge, based solely on its review of the copies of
such reports furnished to the Company and written  representations that no other
reports were required,  all Section 16(a) filing requirements  applicable to its
officers,  directors and greater than 10%  beneficial  owners were complied with
during the fiscal year ended December 31, 1998.
<PAGE>

         During the fiscal year ended  December 31, 1998, the Board of Directors
held four  meetings  (including  regularly  scheduled,  telephonic  and  special
meetings).  During  that  time,  all  members  of the  Board  attended  at least
Seventy-Five Percent (75%) of the meetings held subsequent to their appointment.

         The Company has a stock option committee (the "Stock Option Committee")
which,  by the terms of the Company's  Stock Option Plans,  is to consist of not
less  than two  members  of the  Board of  Directors  appointed  by the Board of
Directors.  The Stock Option Committee is comprised of James W. Hansen, Miles E.
Efron, and Samuel C. Powell. The Stock Option Committee  determines the terms of
options granted,  including,  but not limited to, the exercise price, the number
of shares  subject  to the option and the terms and  conditions  of the  option.
During the fiscal year ended December 31, 1998,  the Stock Option  Committee met
one time and all members of the committee attended at least Seventy-Five Percent
(75%) of the meetings held subsequent to their appointment.

     The Company has an Audit  Committee  which is comprised of James W. Hansen,
Miles E. Efron and, until September 1998, Louis  Perlman.  During the fiscal
year ended  December  31, 1998, the Audit Committee held one meeting.

     The Company has a  Compensation  Committee  which is  comprised of James W.
Hansen,  Miles E. Efron,  and Samuel C.  Powell.  The  Compensation  Committee's
purpose is to  determine  the  compensation  of the  Executive  Officers  of the
Corporation.  During the fiscal year ended December 31, 1998,  the  Compensation
Committee held one meeting.

         The Company does not have a Nominating Committee.

         The Board of Directors  recommends that  Stockholders vote FOR
Proposal 1.


<PAGE>


                                             EXECUTIVE COMPENSATION

         The  following  table and the narrative  text discuss the  compensation
paid during 1998 and the two prior fiscal years to the  Company's  President and
Chief Executive Officer and to the other executive  officers whose annual salary
and bonuses exceeded $100,000 during 1998.

<TABLE>
<CAPTION>

                                           Summary Compensation Table
                                                                         Long Term Compensation
                                            --------------------------------------------------
                            Annual Compensation                            Awards             Payouts

                                                          Other
                                                          Annual     Restricted  Options/    LTIP    All Other
   Name and Principal                                     Compen     Stock        SAR's    Payouts   Compen-
        Position            Year    Salary      Bonus     sation(1)  Awards (2)    (#)       (2)     sation
- -------------------------- ------- --------- ------------ ---------- ----------- --------- --------- -------------
<S>                      <C>      <C>         <C>       <C>        <C>          <C>        <C>      <C>
Harry G. McCoy             1998    $209,615      --          --          --       50,000      --          --
Chairman of the Board      1997    $199,489      --          --          --         --        --          --
and President (3)          1996    $166,648      --          --          --         --        --          --

Richard J. Braun           1998    $209,615      --          --          --       50,000      --       $9,060(5)
Chief  Executive           1997    $193,479      --          --          --         --        --       $3,195(5)
Officer(4)                 1996    $ 72,696      --          --          --         --        --          --

Kevin J. Wiersma           1998    $ 92,144  $ 11,700        --          --        5,000      --          --
Vice President,
Controller  and Secretary
(6)

Peter J. Heath             1998    $ 91,868      --          --          --       12,500     --       $46,154
Vice President of Finance  1997    $119,235      --          --          --         --       --       $ 3,000
and Chief  Financial       1996    $113,677   $30,000        --          --        3,750     --       $ 1,400
Officer(7)

</TABLE>

(1)      Other Annual  Compensation for executive officers is not reported as it
         is less than the required  reporting  threshold of the  Securities  and
         Exchange Commission.

(2)      Not applicable. No compensation of this type received.

(3)      Dr. McCoy was appointed Chairman of the Board and President on July
         3, 1996.

(4)      Mr. Braun was appointed Chief Executive Officer on July 25, 1996.

(5)      Includes $9,060 of premiums paid for by the Company for a disability
         insurance policy on Mr. Braun for 1998 and $3,195 for 1997.

(6)      Mr. Wiersma was appointed Vice President and Secretary on July 20,1998.

(7)      Mr.  Heath  resigned as Vice  President  of Finance and CFO on July 31,
         1998. As part of Mr.  Heath's  separation  agreement,  he is to receive
         $90,000  payable over nine  months.  During  1998,  Mr. Heath  received
         $46,154 pursuant to the separation agreement.

<PAGE>

Stock Options Granted During Fiscal Year

         The  following  table sets forth  information  about the stock  options
granted to the named executive officers of the Company during 1998.

<TABLE>
<CAPTION>

                                    Option Grants In Last Fiscal Year
                                                                                        Potential Realized
                                                                                        Value at Assumed
                                                                                        Annual Rates of
                                                                                        Stock Price
                                                                                        Appreciation for
                                                                                        Option Term
                    Individual Grants

                           % of Total
                           Options
                 Number    Granted to
                     of    Employees        Exercise
                 Options   in Fiscal        Price             Expiration       5% ($)         10%( $)
Name             Granted   Year             ($/Sh)            Date              (2)            (2)
- ---------------------------------------------------------------------------------------------------------
<S>            <C>       <C>              <C>               <C>               <C>         <C>
Harry G.
McCoy            50,000      25%             $8.75             03/01/08          $275,141    $697,262

Richard J.
Braun            50,000      25%             $8.75             03/01/08          $275,141    $697,262

Kevin J
Wiersma           5,000      2%              $8.75             03/01/08          $27,514     $ 69,726

Peter J.
Heath (1)        10,000      5%              $8.75             03/01/08          $55,028     $139,452
                  2,500      1%              $8.75             07/31/03          $ 7,440     $ 37,659

</TABLE>

(1)      Mr. Heath  resigned as Vice  President  of Finance and Chief  Financial
         Officer on 7/31/98.  10,000  options to acquire  shares  were  canceled
         effective  7/31/98.  The remaining 2,500 options to acquire shares were
         fully vested at 12/31/98.

(2)      The  potential  realizable  value of the  options  reported  above  was
         calculated by assuming 5% and 10% annual rates of  appreciation  of the
         Common Stock of the Company from the date of grant of the options until
         the   expiration  of  the  options.   These  assumed  annual  rates  of
         appreciation  were used in compliance  with the rules of the Securities
         and Exchange  Commission and are not intended to forecast  future price
         appreciation of the Common Stock of the Company.  The Company chose not
         to report the present  value of the  options,  which is an  alternative
         under  Securities and Exchange  Commission  rules,  because the Company
         does not believe any formula will determine with reasonable  accuracy a
         present  value based on unknown or volatile  factors.  The actual value
         realized from the options could be  substantially  higher or lower than
         the values  reported above,  depending upon the future  appreciation or
         depreciation  of the Common  Stock  during  the  option  period and the
         timing of exercise of the options.

Stock Options Exercised During Fiscal Year and Year-End Values of
Unexercised Options

         The following table sets forth information about the stock options held
by the named executive officers of the Company at December 31, 1998.

<PAGE>
<TABLE>
<CAPTION>

                    Number of
                    Shares                                   Number of Unexercised      Value  of  Unexercised In-the
                    Acquired                 Value            Options at FY-End         Money Options at FY-End
Name                on Exercise              Realized        Exercisable/Unexercisable  Exercisable/Unexercisable (1)
<S>               <C>                      <C>             <C>                         <C>
Harry G. McCoy       -                        -                   31,894/18,105                    $0/$0
Richard J. Braun     -                        -                   31,894/18,105                    $0/$0
Peter J. Heath       -                        -                    2,500/  -                       $0/$0
Kevin J. Wiersma     -                        -                   1,521/3,478                      $0/$0
- ----------------------------
</TABLE>

     (1) The closing  price of the Common  Stock of the Company at December  31,
1998 was $5.00 per share. (Share price adjusted to reflect reverse split.)

Long-Term Incentive Plans and Pension Plans

         The Company does not  contribute  to any  Long-Term  Incentive  Plan or
Pension Plan for its executive  officers as those terms are defined in the rules
of the  Securities  and  Exchange  Commission.  The Company  relies on its stock
option plans to provide long-term incentives for executive officers. The Company
has three stock  option  plans,  a 1983 Stock  Option Plan for  employees  which
expired on June 23, 1993, the Equity  Compensation Plan which was adopted by the
shareholders  of the annual meeting in 1993 to replace the 1983 Incentive  Stock
Option Plan, and a 1991 Non-Employee Director's Plan for members of the Board of
Directors who are not employees of the Company.

Compensation of Directors

         All  directors  who are not  employees of the Company  receive $500 per
month for their service as a director.  All directors  are also  reimbursed  for
expenses incurred in attending board of directors' meetings and participating in
other activities.

Employment Contracts

         Harry G. McCoy, Chairman of the Board of Directors and President of the
Company, has an employment agreement with the Company covering the period ending
December  31,  2001,  which  by its  term is  extended  thereafter  in  one-year
increments  unless Dr.  McCoy  provides  written  notice of  termination  to the
Company at least sixty (60) days prior to the date of termination. The agreement
may also be terminated  by mutual  consent or due to death or for "cause," or as
described  below. The employment  agreement  provides for an annual salary of at
least  $199,650  and certain  fringe  benefits.  If Dr.  McCoy's  employment  is
terminated  by the  Company  other than for cause,  or if Dr.  McCoy  chooses to
terminate the agreement voluntarily, following (i) a change in control; (ii) any
relocation  to which Dr.  McCoy has not  agreed to of  greater  than  fifty (50)
miles;   or  (iii)  any  material   reduction  in  the  level  of  Dr.   McCoy's
responsibility,  position,  authorities or duties;  or (iv) the Company breaches
any of its  obligations  under the  Agreement,  Dr.  McCoy will be entitled to a
Severance Award. The Severance Award consists of Dr. McCoy's base salary, health
insurance  and bonus plan  payments for the greater of twelve (12) months or the
then remaining term of employment under the Agreement.

         The employment agreement contains a Covenant Not to Compete whereby for
a period of twelve (12) months  after the  termination  of  employment  with the
Company,  Dr. McCoy agrees that he will not, directly or indirectly,  either (a)
have any interest in (b) enter the employment of, (c) act as agent,  broker,  or
distributor for or advisor or consultant to, or (d) provide  information  useful

<PAGE>

in conducting  the business of the Company to solicit  customers or employees on
behalf of the Company to any person, firm,  corporation or business entity which
is  engaged,  or which  Dr.  McCoy  reasonably  knows is  undertaking  to become
engaged, in the United States in the business of the Company.

         Richard J. Braun, Chief Executive Officer,  has an employment agreement
with the Company with the same terms as Dr. McCoy.

         Kevin Wiersma,  Vice President and Controller has a severance agreement
with the Company  covering the period  December  31, 2000,  which by its term is
extended  thereafter  in one-year  increments  unless  either the Company or Mr.
Wiersma provides written notice to the other party at least six (6) months prior
to the end of the original  term or each renewal  period or unless the agreement
is otherwise terminated due to death, permanent disability,  or for "cause." The
employment  agreement  provides  for an annual  salary of at least  $95,000  and
certain fringe benefits. If Mr. Wiersma's employment with the Company terminates
during  the  term of the  agreement  involuntarily,  other  than an  involuntary
termination on account of misconduct,  he will be entitled to a Severance Award.
The Severance Award consists of payment of an amount equal to Mr. Wiersma's then
current annual salary plus certain health benefits over the course of the twelve
(12) month period following Mr. Wieresma's termination.

         Three other key  employees  of the Company  have  severance  agreements
similar to Mr. Wiersma's agreement.

Compensation Committee and Decision Making

         The  compensation  of  executive  officers  of the Company for 1998 was
determined by the Compensation  Committee which is currently  comprised of James
W. Hansen, Miles E. Efron, and Samuel C. Powell. Stock options are awarded under
the Company's Equity  Compensation  Plan and  Non-Employee  Director Plan by the
Compensation  Committee.  All  non-employee  directors  were eligible to receive
stock options under the Company's 1991  Non-Employee  Director Plan,  which is a
formula  plan in  accordance  with the  requirements  of Rule  16b-3  under  the
Securities Act of 1934, as amended.

Report of the Compensation Committee on Executive Compensation

In General

         The Committee has three primary goals for executive compensation at the
Company.

o        Retaining good performers,
o        Rewarding executives appropriately for performance, and
o        Aligning executives' interests with those of stockholders.

         Currently,  executive pay consists of three  elements that are designed
to meet those objectives:

o    Base salary is paid based  primarily on job  responsibilities  and industry
     job comparison.  The Committee believes that base salaries at approximately
     industry averages are essential to retaining good performers.
o    Stock options,  which allow  executives to benefit when the market price of
     the Company's stock increases.
o    Bonuses to be paid upon the attainment of certain financial  objectives and
     individual circumstances when warranted.

Following is additional information regarding each of the above elements.
<PAGE>

Base Salary

         Base  salary  increases  for  executive  officers  have been modest and
consistent with job performance and increases in responsibility.

Bonus

         Kevin   Wiersma   received  a  bonus  in  1998  as  part  of  incentive
compensation for meeting certain performance-related goals.

Stock Options

         In 1998, certain executive officers received incentive stock options to
purchase  a total of  117,500  shares.  The  number of  options  granted  to the
executive  officers  represented 59% of the total options granted in 1998 to all
employees.

Summary

         Currently,  the Company's  executive  compensation  program rewards the
following elements of performance.

o        Individual performance is rewarded through continued employment with
         the Company.
o        Stock price performance is rewarded through increases in the value of
         stock options.
o        Financial  performance  of the Company is rewarded  through  payments
         of bonuses upon the attainment of certain financial goals.

         The Committee  believes that the current  program has been effective in
rewarding executives  appropriately for performance,  retaining good performers,
and  aligning  executives'  interests  with  those of  stockholders.  While  the
Committee is satisfied  with the current  compensation  system,  it reserves the
right to make  changes to the program as are  necessary  to continue to meet its
stated goals in future years.

         Benefits   also  are  offered  to  officers   that  are  not  based  on
performance.  Such  benefits  provide a safety net of protection in the event of
illness,  disability,  death, retirement,  etc. Such a safety net is provided to
all full time employees of the Company.

Chief Executive Officer Pay

         Amounts earned during 1998 by the Chief Executive  Officer,  Richard J.
Braun, are shown in the Summary Compensation Table.  Achievements by the Company
which were deemed material to the Chief Executive Officer's compensation include
the  attainment  of  profitability  for 1997 for the first time in the Company's
history. For the year ended December 31, 1998, the Compensation  Committee used,
in its  deliberations  on  executive  compensation,  these  criteria  and  other
accomplishments.

   Submitted by the Compensation Committee of the Company's Board of Directors

                                 James W. Hansen
                                 Miles E. Efron
                                Samuel C. Powell
<PAGE>

Performance Graph

       The graph  shown below is a line  presentation  comparing  the  Company's
cumulative  five-year  shareholder  returns on an indexed basis with the S&P 500
Index and the S&P  Health  Care Index for the  five-year  period  commencing  on
December 31, 1993 and ending on December 31, 1998. The total return assumes that
dividends  were  reinvested  quarterly  and is  based  on a $100  investment  on
December 31, 1993.

                      Comparative Five-Year Total Returns*
                MEDTOX Scientific, Inc., S&P 500, S&P Health Care
                     (Performance results through 12/31/98)

(Comparative chart appears here. The plot points are below.)

              1993    1994     1995     1996      1997    1998
- -------------------------------------------------------------------------------
TOX         $100.00  $107.14  $ 82.14  $ 17.86  $  8.93  $  7.14
S&P 500     $100.00  $101.32  $139.40  $171.40  $228.59  $293.89
S&P Hcare   $100.00  $113.15  $178.44  $215.38  $309.43  $446.04
- -------------------------------------------------------------------------------

Assumes $100  invested at the close of trading on the last trading day preceding
the first day of the fifth preceding fiscal year in MEDTOX common stock, S&P 500
Index, and S&P Health Care Index.

* Cumulative total return assumes reinvestment of dividends.
                           Source: Russell/Mellon, Analytical Services Company.

Factual  material is obtained  from  sources  believed to be  reliable,  but the
publisher is not responsible for any errors or omissions contained herein.
<PAGE>

                 CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

Lease Agreement with Dr. Samuel C. Powell

         In July 1986,  the Company  executed a lease  agreement with Dr. Powell
providing  for a lease to the  Company of  approximately  16,743  square feet of
space at 1238 Anthony Road, Burlington,  North Carolina. Since 1986, the Company
has expanded the space rented  under the lease to  approximately  33,000  square
feet. Upon the expiration of the original lease,  the Company entered into a new
lease with Dr.  Powell for the same space and at the same base rental rate for a
term of one year ending on May 31, 1990. Effective June 1, 1990, the Company has
been  leasing the space on a  month-to-month  basis.  The  Company is  currently
leasing space at a rate of approximately  $10,000 per month. The Company intends
to negotiate a new lease with Dr.  Powell in the near future.  The Company holds
certain rights of first refusal to lease  additional space in the building if it
becomes  available  (the building  contains a total of 42,900 square feet).  The
total rent paid by the  Company  to Dr.  Powell  during  the  fiscal  year ended
December  31, 1998 was  approximately  $122,000.  The Company  believes the rent
amount paid to Dr. Powell is consistent with market rates.

                                   PROPOSAL 2
                    AMENDMENT TO CERTIFICATE OF INCORPORATION
             TO INCREASE NUMBER OF AUTHORIZED SHARES OF COMMON STOCK

         The Company's  Certificate of  Incorporation  presently  authorizes the
issuance  of a total of  3,750,000  shares of common  stock,  par value $.15 per
share. Of such 3,750,000 presently authorized shares of common stock,  2,903,236
shares  were  issued  and  outstanding  as of July 20,  1999.  In  addition,  an
aggregate of 454,196  shares has been reserved for issuance as of July 20, 1999,
as summarized in the following table:

Shares of Common Stock Reserved For                 Number of Shares Reserved
  Subordinated notes 12%                                        28,750
Common Stock Options
  Incentive                                                    206,197
  Non-Employee Director                                         11,416
  Non-Qualified                                                203,405
Qualified Employee Stock Purchase Plan                           4,428
                                                               454,196

         The Board of  Directors  has  approved an  amendment  to the  Company's
Certificate  of  Incorporation  to increase the number of  authorized  shares of
common stock from 3,750,000 to 7,400,000.  The Company has no current  intention
of issuing the additional authorized shares.

         The additional  common stock, if so authorized,  would be issued at the
discretion  of  the  Board  of  Directors  without  any  further  action  by the
stockholders except as required by applicable law or regulation. Shares of stock

<PAGE>

will be issued only upon determination by the Board of Directors that a proposed
issuance is in the best  interests of the Company.  As noted above,  the Company
has no current intention of issuing the additional authorized shares.

         Accordingly, the Board of Directors has proposed that Article Fourth of
the Company's  Certificate of  Incorporation  be amended to increase its capital
stock. As so amended,  this provision of the Certificate of Incorporation  would
read as set forth on Appendix A hereto.

         The Board of Directors recommends a vote FOR Proposal 2. An affirmative
vote by holders of a majority of the outstanding shares of common stock entitled
to vote at the annual meeting is required to approve the amendment.

                                   PROPOSAL 3
                   APPROVAL OF A CLASSIFIED BOARD OF DIRECTORS

         The  Company's  Board  of  Directors  has   unanimously   approved  and
recommended that the stockholders of the Company approve an amendment to Article
Fifth,  Section  1, to the  Certificate  of  Incorporation  to  provide  for the
classification  of the Board of Directors  into three classes of directors  with
staggered terms of office.

         The Company's  By-Laws now provide that all directors are to be elected
annually  for  a  term  of  one  year.  Delaware  law  permits  provisions  in a
certificate of incorporation or by-law approved by stockholders that provide for
a classified board of directors.  The proposed classified board amendment to the
Certificate of Incorporation and conforming amendments to the By-Laws, described
in Appendix B to this Proxy  Statement,  would  provide that  directors  will be
classified into three classes, as nearly equal in number as possible.  One class
(Class I) would hold  office  initially  for a term  expiring at the 2000 Annual
Meeting;  another  class  (Class  II) would  hold  office  initially  for a term
expiring at the 2001 Annual  Meeting;  and another  class (Class III) would hold
office initially for a term expiring at the 2002 Annual Meeting.  At each Annual
Meeting following this initial  classification  and election,  the successors to
the class of directors whose terms expire at that meeting would be elected for a
term of office to expire at the third  succeeding  Annual  Meeting  after  their
election and until their  successors  have been duly elected and qualified.  See
"Election of Directors" as to the composition of each class of directors if this
proposal is adopted.

         The proposed  classified board amendment will significantly  extend the
time  required to effect a change in control of the Board of  Directors  and may
discourage hostile takeover bids for the Company. Currently, a change in control
of the Board of Directors can be made by stockholders holding a plurality of the
votes cast at a single Annual  Meeting.  If the Company  implements a classified
board  of  directors,  it will  take at least  two  Annual  Meetings  for even a
majority of  stockholders to make a change in control of the Board of Directors,
because only a minority of the directors will be elected at each meeting.

         Under Delaware law,  directors chosen to fill vacancies on a classified
board  shall hold  office  until the next  election  of the class for which such
directors  shall have been chosen,  and until their  successors  are elected and
qualified.   Delaware  law  also  provides  that,   unless  the  certificate  of

<PAGE>

incorporation  provides  otherwise,  directors  serving on a classified board of
directors  may  be  removed  only  for  cause.  The  Company's   Certificate  of
Incorporation does not provide otherwise.  Accordingly,  if the classified board
proposal  is  approved  by  the  stockholders,   conforming  By-Law  provisions,
substantially in the form attached as Appendix B to this Proxy  Statement,  will
be implemented. Presently, all directors of the Company are elected annually and
all of the directors may be removed,  with or without cause,  by a majority vote
of the  outstanding  shares  of  the  Common  Stock.  Cumulative  voting  is not
authorized by the Certificate of Incorporation.

         The  classified  board  proposal is designed to assure  continuity  and
stability in the board of directors'  leadership and policies.  While management
has not  experienced any problems with such continuity in the past, it wishes to
ensure that this experience will continue.  The Board of Directors also believes
that the  classified  board  proposal  will  assist  the Board of  Directors  in
protecting  the  interests  of the  Company's  stockholders  in the  event of an
unsolicited offer for the Company.

         Because of the additional  time required to change control of the Board
of Directors,  the  classified  board  proposal will tend to perpetuate  present
management.  Without  the  ability to obtain  immediate  control of the Board of
Directors,  a takeover  bidder will not be able to take  action to remove  other
impediments to its acquisition of the Company,  including,  as discussed  above,
the redemption of the Company's  stockholder  rights,  the terms of which create
obstacles to an acquisition of the Company and empower the Board of Directors to
effect such a redemption.  Because the  classified  board proposal will increase
the  amount of time  required  for a  takeover  bidder to obtain  control of the
Company without the cooperation of the Board of Directors,  even if the takeover
bidder were to acquire a majority of the Company's  outstanding  stock,  it will
tend to discourage  certain tender offers,  perhaps including some tender offers
that  stockholders  may feel would be in their best  interests.  The  classified
board proposal will also make it more difficult for the  stockholders  to change
the composition of the Board of Directors even if the stockholders  believe such
a change would be desirable.

         The Board of Directors recommends a vote FOR Proposal 3. An affirmative
vote by holders of a majority of the outstanding shares of common stock entitled
to vote at the annual meeting is required to approve the amendment.

                                   PROPOSAL 4
                     APPROVAL FOR AMENDMENT TO THE COMPANY'S
                     QUALIFIED EMPLOYEE STOCK PURCHASE PLAN

         On March 13, 1986 the Company  adopted,  and on September  11, 1986 the
shareholders of the Company approved,  and on November 20, 1996 the shareholders
amended,  the  Qualified  Employee  Stock  Purchase  Plan  pursuant to which the
employees of the Company are given an opportunity to acquire Common Stock of the
Company (the "Stock") up to a certain percentage of each employee's compensation
through payroll  deductions.  The Board of Directors of the Company has approved
an amendment to the Qualified  Employee Stock Purchase Plan, as set forth in the
form attached hereto as Appendix C (the "Qualified  Plan"),  which increases the

<PAGE>

number of shares of Common Stock  subject to the  Qualified  Plan from 25,000 to
150,000 shares. The affirmative vote of a majority of the shares of Common Stock
present, or represented,  and entitled to vote at the Annual Meeting is required
for approval of the amendment to the Qualified Plan.

         The ability to offer the Company's  employees an opportunity to acquire
shares of the Common Stock of the Company through  payroll  withholding at a 15%
discount from fair market value provides  another means by which the Company may
compensate  its employees and provide  competitive  compensation  levels without
increasing its cash requirements.  By providing competitive  compensation levels
the  Company  can attract and retain  competent  personnel.  Further,  the Board
believes that an employee  stock  ownership  plan,  such as the Qualified  Plan,
provides an incentive to employees to promote the best  interests of the Company
because  they have an  opportunity  to  acquire a  proprietary  interest  in the
Company and ultimately to benefit from appreciation in the value of the Stock.

         The Board of Directors recommends a vote FOR Proposal 4.

Description of Plan

         The following  description of the Qualified Plan is merely a summary of
the plan and is  qualified  in its entirety by reference to the full text of the
Qualified  Plan. If any part of the  description of the Qualified Plan contained
in this  document  states  anything  different  from the formal legal  documents
governing the Qualified Plan, the formal legal plan documents will be considered
correct.

         The Qualified  Plan is not generally  subject to the  provisions of the
Employee Retirement Income Security Act of 1974, as amended ("ERISA").  The Plan
is not a qualified plan under Section 401 of the Code.

         Nature and  Purpose.  The Plan allows  eligible  employees  to purchase
shares of the Common Stock of the Company through payroll  deductions at a price
equal to 85% of the lesser of the fair market  value of the stock on the date of
the Company's receipt of the subscription or the date of the employee's exercise
of the right to purchase such shares.  As amended,  the maximum number of shares
that each eligible  employee may subscribe for under the Qualified Plan shall be
subject  to  such   limitations  as  from  time  to  time   established  by  the
Administrative   Committee,   which  limitations  shall  apply  equally  to  all
participants.  The receipt of an approved  subscription form by the Company from
an eligible  employee  shall be treated as the grant of a right to purchase  the
shares subscribed for, and the accrual of a sufficient amount in such employee's
account to acquire a minimum  of 100 shares of stock at the  subscription  price
shall be treated as the exercise of such purchase right.

         The  Qualified  Plan  is  designed  to  attract  and  retain  competent
personnel,  to allow the Company to compete with other companies with respect to
compensation,  to motivate  Company  employees to use their best efforts for the
benefit of the Company,  and to provide  employees an  opportunity  to acquire a

<PAGE>

proprietary  interest in the Company  thereby  encouraging  the promotion of the
Company's  best  interests and giving the employees an  opportunity  to share in
future growth of the Company.

         Administration.  The  Qualified  Plan is  administered  by a  committee
appointed  by the  Board  of  Directors  of  the  Company  (the  "Administration
Committee").   The  Administration   Committee  is  comprised  of  two  or  more
non-employee  directors.  In order to retain the services of  qualified  outside
directors,  the Company has adopted a Non-Employee Director Stock Option Plan to
compensate  directors  for their  service on the Board as well as on  committees
thereof.  The members of the Stock Option Committee are deemed to be the members
of the  Administration  Committee until otherwise  designated by the Board.  The
Administration  Committee has the exclusive right to interpret,  prescribe rules
and regulations for, and administer the Qualified Plan. In the event there is no
market for the Stock, the Administration Committee may determine the fair market
value of the Stock for purposes of the Qualified Plan. Also, the committee shall
be entitled to reduce employee's  subscriptions in excess of prescribed  amounts
under certain circumstances.

         Securities to be Offered.  The additional  shares,  if approved,  would
authorize the Company to issue 150,000 shares of Stock under the Qualified Plan,
which  represents  an increase of 125,000  shares  from the  previously  adopted
version of the plan. Of the 25,000 shares previously approved for issuance under
the plan, only 4,428 shares remain available for subscription  under the plan as
of July 20, 1999.  The Board  believes  that an increase in the number of shares
authorized  under the Qualified  Plan is warranted due to the limited  number of
shares remaining available for subscription.

     Subscription  Amount.  The Qualified Plan provides that the  Administration
Committee  shall  establish  from time to time the maximum number of shares that
may be  acquired by any  employee  under the plan and such  maximum  shall apply
equally to all eligible employees.  The plan allows an employee to subscribe for
less than the maximum number of shares and subsequently subscribe for additional
shares until he has subscribed for the maximum number of shares permitted.  Each
new subscription  shall be treated for all purposes under the plan as a separate
grant of a right to purchase the number of shares  indicated on the subscription
form.  However,  in order to be able to  subscribe  for  additional  shares,  an
employee  must wait at least six months from the date of his last  subscription,
or three  months from the date of the  withdrawal  of a prior  subscription,  or
until all  subscriptions  outstanding to acquire shares under the Qualified Plan
have been paid in full.

         Subscription  Price/Purchase  Price. The  subscription  price for Stock
acquired  under the plan is 85% of the fair market value of the Stock on the day
the executed  subscription  form is received by the Company.  The purchase price
for shares of Stock is the lesser of the  subscription  price or 85% of the fair
market value on the day the right to purchase is exercised.  The Qualified  Plan
includes a formula for determining the fair market value of the Stock on a given
date which expands upon the sources for determining the value of the Stock based
upon various possible markets for the Stock,  including  methods for determining
the fair  market  value of the Stock if it is traded  on a  national  securities
exchange,  quoted on the National  Association  of Securities  Dealer  Automated
Quotation ("NASDAQ") System or otherwise in the  over-the-counter  market, or if

<PAGE>

it is not traded or quoted at such time. Generally,  the fair market value shall
be based upon the last sales  price of the Stock on a given date if a minimum of
100 shares are sold on such date,  or if no shares are sold on such date,  based
upon the  average of the high bid and low asked  prices on such  date,  or if no
prices are available on such date,  based upon the last sales price of the Stock
on the last prior date on which a minimum of 100 shares were sold.  If the Stock
is not  traded on an  exchange  or  quoted by NASDAQ or in the  over-the-counter
market,  then the  Administrative  Committee  shall be permitted to determine in
good faith the fair market value by any appropriate method. The closing price of
the Common Stock of the Company on the American  Stock Exchange on July 20, 1999
was $8.875 per share.

         Limitations on Subscriptions.  Employees who own stock possessing 5% or
more of the total combined  voting power or value of all classes of stock of the
Company  are not  eligible to  subscribe  for Stock  under the  Qualified  Plan.
Further,  no employee may subscribe to purchase  Stock under all stock  purchase
plans of the Company at a rate which exceeds $25,000 of the fair market value of
such stock for any calendar year in which such subscription is outstanding under
the Qualified Plan.

         Payroll  Deductions.  The  subscription  price under the Qualified Plan
must be paid by payroll  deduction  from the employee's  compensation.  The plan
allows the  Administration  Committee to establish  procedures  and  limitations
regarding payroll deductions;  provided,  however, that no payment period may be
structured so that the date of exercise of the purchase rights exceeds more than
twenty-seven (27) months from the date of grant of the purchase rights.  Payroll
deductions shall begin when specified by the employee in the  subscription  form
or as soon as practicable thereafter but in no event later than two months after
the date specified by the employee.

         Issuance of Stock.  The Stock will only be issued by the  Company  when
the employee has completed  paying for at least 100 shares (or any lesser amount
of shares under  subscription) at the subscription  price. If the purchase price
is less than the  subscription  price,  the  employee  shall not be  entitled to
acquire more shares than that number for which he subscribed.  The plan provides
that the  employee  shall not be deemed  to own the stock  subscribed  for until
issuance of the stock certificate representing such shares.

         Withdrawal of  Subscription.  An employee may withdraw his subscription
at any time for any  shares  for which the  right to  purchase  has not yet been
exercised  and receive a refund of the balance in his  account.  An employee who
withdraws  a  subscription,  however,  shall not be entitled  to  subscribe  for
additional  shares  until  at  least  three  (3)  months  after  the  last  such
withdrawal.

         Termination  of  Employment.   Upon   termination  of  a  participating
employee's services because of death,  permanent disability or retirement at age
55 or thereafter,  the employee (or his estate) may prepay any  subscription for
Stock within three (3) months thereafter in the case of permanent  disability or
retirement, or within twelve (12) months thereafter in the case of death. If the

<PAGE>

participating  employee's  services are  terminated  for any other  reason,  the
employee  will only be entitled to receive back the balance of his  subscription
account.

         Transferability.  Neither the right of an  employee to purchase  shares
under the Qualified  Plan,  nor his account  balance,  may be transferred by the
employee by way of assignment, pledge or otherwise, except that, in the event of
death of the  employee,  such rights may be  transferred  by will or the laws of
descent and distribution.

         Termination of Plan.  The Qualified Plan became  effective on September
11,  1986  following  its  approval  by the  stockholders  of the  Company.  The
amendment to the plan is subject to and will become  effective  upon approval by
the  stockholders of the Company.  The Board may terminate the Qualified Plan at
any time,  and may amend the  Qualified  Plan from time to time,  subject to any
approval of the  stockholders  of the Company that may be required in order that
the Qualified Plan shall continue to qualify under Section 423 of the Code. Upon
termination  of  the  Qualified  Plan,  participating  employees  shall,  at the
discretion of the Board, either be permitted to complete unpaid subscriptions in
a manner  determined  by the  Administrative  Committee  or shall be entitled to
receive the balance in their subscription  account in satisfaction of all rights
under the Qualified Plan.

         Interpretation  of Plan. The Qualified  Plan is intended,  and shall be
interpreted,  to meet and comply with all the requirements of Section 423 of the
Code, and related provisions.

Federal Income Tax Consequences

         The  Qualified   Plan  is  intended  to  provide   employees  with  the
opportunity to receive the special tax treatment  afforded by Section 423 of the
Internal Revenue Code.

         Under existing law, the following description  summarizes the principal
Federal  Income Tax  Consequences  of the purchase and  disposition of shares of
Stock under the Qualified Plan.

         Purchase of Shares. An employee does not realize,  and does not have to
report any income for the year in which he subscribes  nor for the year in which
he pays for Stock under the Qualified  Plan,  even though his purchase  price is
the  lesser  of 85% of the  fair  market  value  of the  Stock  on the  date  he
subscribes, or on the date the right to purchase is exercised.

         Disposition  of  Shares.  Section  423 of  the  Internal  Revenue  Code
establishes a holding period which is important in  determining  how any gain on
disposition of shares acquired under the Qualified Plan is to be taxed. The term
"disposition" generally includes every sale, exchange, gift or transfer of legal
title except  transfers made as the result of an employee's  death.  The holding
period  provided  under Section 423 is the later of two (2) years after the date
the  employee  subscribed  or twelve (12)  months  after the date the shares are
transferred to him. An employee may have a different holding period for each 100
share unit of Stock acquired under the Qualified Plan.
<PAGE>

         The issue of shares of Stock in the joint names of employee and another
person is not  considered a  disposition.  Similarly,  the issue of shares in an
employee's name and the subsequent  transfer of such shares into the joint names
of the employee and another person do not constitute a disposition.

         Sale After End of Holding  Period.  When an  employee  sells his shares
after the specified  holding  period,  he is required to report the following on
his Federal Income Tax Return for the year in which the sale occurs:

         Ordinary Income:  The employee must report ordinary income in the
         amount of the lesser of:

         (1)      15% of the fair market value of the Stock on the date of his
         subscription,  or on the date of purchase, whichever is lower, or

         (2)      any  excess of the fair  market  value of the Stock on the
         date of sale over the purchase price.

         If the  employee's  purchase price exceeds the fair market value on the
date of sale, no amount is reported as ordinary income.

         Capital Gain or Loss: If the fair market value of the Stock on the date
of sale exceeds the lesser of the fair market value on the date of  subscription
or the date of purchase,  the employee  must report the amount of such excess as
long term capital  gain.  On the other hand,  if the purchase  price exceeds the
fair market value on the date of sale, such excess is a long term capital loss.

         Sale Before End of Holding  Period.  When an employee  sells his shares
prior to the end of the specified  holding period,  he is required to report the
following  on his  Federal  Income  Tax  Return  for the year in which  the sale
occurs:

         Ordinary Income: The employee must report the excess of the fair market
value of the Stock on the date of exercise  over his purchase  price as ordinary
income.  The  "date of  exercise"  is the date  when an  employee's  account  is
credited with  sufficient  funds to purchase 100 shares of Stock (or such lesser
number as remain under a  subscription  agreement).  Consequently,  the employee
will normally have a different date of exercise for each 100-share unit of Stock
issued under the Plan.

         Capital Gain or Loss: If the fair market value of the Stock on the date
of sale  exceeds the fair market value on the date the  employee  exercised  his
right to receive such shares, he must report such excess as capital gain. On the
other hand,  if the fair market  value on the date of exercise  exceeds the fair
market  value on the date of sale,  the  employee  may report the amount of such
excess as capital loss.  Any such capital gain or loss will be long term capital
gain or loss if the  Stock is sold more  than six (6)  months  after the date of

<PAGE>

exercise,  but  will be short  term  capital  gain or loss if the  Stock is sold
within six (6) months after the date of exercise.

         In the case of a disposition  before the end of the holding period, the
Company  receives  a tax  deduction  equal  to the  amount  of  ordinary  income
recognized by the employee.

                           RELATIONSHIPS WITH AUDITORS

         Effective May 27, 1998, the Company terminated Ernst & Young LLP as its
independent  accounting  firm. The termination of Ernst & Young LLP was approved
by the Audit Committee of the Board of Directors of the Company.

         Ernst & Young LLP's report on the  financial  statements of the Company
for each of the last two fiscal years neither  contained an adverse opinion or a
disclaimer of opinion,  nor was qualified or modified as to  uncertainty,  audit
scope, or accounting principles.

         During the  Company's  two most  recent  fiscal  years and the  interim
period through May 27, 1998, there were no disagreements or "reportable  events"
with Ernst & Young LLP as described in Items 304(a)(1)(iv) and (v) of Regulation
S-K.

         Accordingly,  Ernst & Young LLP has not  advised the Company of (i) the
absence of the internal  controls  necessary for the Company to develop reliable
financial  statements,  (ii) any information which would cause Ernst & Young LLP
to no longer rely on management's representations, or that Ernst & Young LLP was
unwilling to be associated with the financial statements prepared by management,
(iii)  any  need  to  expand  significantly  the  scope  of  its  audit,  or any
information that if further  investigated may (a) materially impact the fairness
or  reliability  of either a previously  issued  audit report or the  underlying
financial   statements  or  any  financial  statements  for  any  fiscal  period
subsequent  to the date of the most recent  financial  statements  covered by an
audit  report  or  (b)  cause  it  to  be  unwilling  to  rely  on  management's
representations  or be associated with the Company's  financial  statements,  or
(iv) any information that has come to the attention of Ernst & Young LLP that it
concluded  materially  impacts  the  fairness  or  reliability  of either  (a) a
previously issued audit report or the underlying financial statements or (b) any
financial  statements  issued  or  to  be  issued  covering  any  fiscal  period
subsequent  to the date of the most recent  financial  statements  covered by an
audit report.

         Effective  June 3, 1998, the Company  engaged  Deloitte & Touche LLP as
its independent  accounting firm. Neither the Company or any of its subsidiaries
has had any prior relationships with Deloitte & Touche LLP.

         It is expected  that  representatives  of Deloitte & Touche LLP will be
present at the Annual Meeting and available to respond to appropriate questions.

<PAGE>

                          OTHER BUSINESS OF THE MEETING

         Management  is not  aware of any  matters  to come  before  the  Annual
Meeting  other than those stated in the Proxy  Statement.  However,  inasmuch as
matters of which  management is not now aware may come before the meeting or any
adjournment thereof, the Proxies confer discretionary  authority with respect to
acting thereon,  and the persons named in such properly  executed Proxies intend
to vote,  act and consent in  accordance  with their best  judgment with respect
thereto. Upon receipt of such Proxies (in the form enclosed) in time for voting,
the shares  represented  thereby will be voted as  indicated  thereon and in the
Proxy Statement.

                  DATES FOR SUBMISSION OF STOCKHOLDER PROPOSALS


         Any proposal,  relating to a proper  subject,  which a Stockholder  may
intend to present for action at the Company's  Annual Meeting of Stockholders in
2000,  and which such  Stockholder  may wish to have  included in the  Company's
proxy  materials for such meeting,  in  accordance  with the  provisions of Rule
14a-8 promulgated under the Exchange Act, must be received in proper form by the
Company addressed to Mr. Richard J. Braun, Chief Executive Officer,  and sent by
registered  mail,  return  receipt  requested,  and  received  at the  Company's
principal executive office at 402 West County Road D, St. Paul, Minnesota 55112,
not later than April 12, 2000.

         Any proposal,  relating to a proper  subject,  which a stockholder  may
wish to present for action at the Company's  Annual Meeting of  Stockholders  in
2000,  whether or not such Stockholder  wishes to have such proposal included in
the Company's proxy materials for such meeting,  must, pursuant to the Company's
By-laws,  be the subject of a written notice delivered to the Company  addressed
to Mr. Richard J. Braun, Chief Executive  Officer,  and sent by registered mail,
return  receipt  requested,  and received at the Company's  principal  executive
office at 402 West  County Road D, St.  Paul,  Minnesota  55112,  not less than
60 days or more than 90 days prior to the Annual Meeting date in 2000.


                                      By order of the Board of Directors,


                                      HARRY G. McCOY
                                      Chairman of the Board
                                      and President


St. Paul, Minnesota
August 9, 1999


COPIES OF THE COMPANY'S  ANNUAL REPORT ON FORM 10-K FOR THE YEAR ENDED  DECEMBER
31, 1998 MAY BE OBTAINED  WITHOUT  CHARGE BY ANY  STOCKHOLDER  TO WHOM THE PROXY
STATEMENT IS SENT,  UPON WRITTEN  REQUEST TO THE SECRETARY,  MEDTOX  SCIENTIFIC,
INC., 402 WEST COUNTY ROAD D, ST. PAUL, MINNESOTA 55112.

<PAGE>
                              AVAILABLE INFORMATION

         The  Company  is  subject  to  the  informational  requirements  of the
Securities Exchange Act of 1934 (the "Exchange Act") and in accordance therewith
files reports,  proxy  statements and other  information with the Securities and
Exchange  Commission (the  "Commission").  Reports,  proxy  statements and other
information  filed by the  Company  can be  inspected  and  copied at the public
reference facilities  maintained by the Commission at Judiciary Plaza, 450 Fifth
Street, N.W.,  Washington,  D.C. 20549 and at its Regional Offices located at 75
Park  Place,  New  York,  New York  10007,  and the John C.  Kluczynski  Federal
Building,  230 South Dearborn Street,  Chicago,  Illinois 60604.  Copies of such
material can be obtained from the Public Reference  Section of the Commission at
Judiciary Plaza, 450 Fifth Street, N.W., Washington, D.C. 20549 upon request and
payment  of the  prescribed  fees.  The  Commission  maintains  a web site  that
contains  reports,  proxy and  information  statements,  and  other  information
regarding issues that are filed electronically with the Commission.  The address
of the web site is HTTP://WWW.SEC.GOV.

         The  Company's  Common Stock is listed on the American  Stock  Exchange
(the "AMEX"),  and reports,  proxy statements and other information filed by the
Company can be inspected at such exchange.

                INCORPORATION OF CERTAIN INFORMATION BY REFERENCE

         The  following  documents,  each of which was  previously  filed by the
Company  with the  Commission  pursuant to Section 13 of the  Exchange  Act, are
incorporated herein by reference:

a) The Company's  Annual Report on Form 10-K for the fiscal year ended  December
31, 1998.

         All documents filed by the Company  pursuant to Sections 13(a),  13(c),
14 and 15(d) of the Exchange Act subsequent to the date of this Proxy  Statement
and prior to the Annual Meeting of  Shareholders  to which this Proxy  Statement
relates shall be deemed to be incorporated by reference  herein and to be a part
hereof from the date of the filing of such reports and documents.  Any statement
contained in a document  incorporated  or deemed to be incorporated by reference
herein shall be deemed to be modified or  superseded  for purposes of this Proxy
Statement  to the  extent  that a  statement  contained  herein  or in any other
subsequently  filed  document which also is or is deemed to be  incorporated  by
reference herein or in any accompanying Proxy Statement  Supplement  modifies or
supersedes  such statement.  Any such statement so modified or superseded  shall
not be deemed, except as so modified or superseded, to constitute a part of this
Proxy Statement.

         The Company will provide  without charge to each person to whom a Proxy
Statement  is delivered  upon written or oral request of each person,  a copy of
any  documents  incorporated  herein by reference  (other than  exhibits to such
documents unless such exhibits are  specifically  incorporated by reference into
the documents that this Proxy Statement incorporates).  Requests for such copies

<PAGE>

should be directed to MEDTOX SCIENTIFIC,  INC., Attention:  Secretary,  402 West
County Road D, St. Paul, Minnesota 55112, (651) 636-7466.


<PAGE>

                                                                     APPENDIX A

                             MEDTOX SCIENTIFIC, INC.
                             AMENDED ARTICLE FOURTH
                         OF CERTIFICATE OF INCORPORATION

     FOURTH:  The total  number of shares of stock which the  Corporation  shall
have authority to issue is SEVEN MILLION FOUR HUNDRED FIFTY THOUSAND (7,450,000)
shares,  SEVEN  MILLION  FOUR  HUNDRED  THOUSAND  of  which  shall be of a class
designated  as Common Stock with a par value of FIFTEEN  CENTS ($0.15) per share
and FIFTY  THOUSAND of which shall be of a class  designated as Preferred  Stock
with a par  value  of ONE  DOLLAR  ($1.00)  per  share.  All or any  part of the
authorized capital stock of the Corporation may be issued and sold, from time to
time by the  corporation,  without  further  action  by  stockholders,  for such
consideration  (but not less than the par value thereof) and to such persons and
on such terms and  conditions  as may, from time to time, be fixed or determined
by the Board of Directors.  The voting  powers,  designations,  preferences  and
relative,   participating,   optional   or   other   special   rights   and  the
qualifications,  limitations or restrictions thereof, of the classes of stock of
the corporation  which are fixed by this Certificate of  Incorporation,  and the
authority  vested in the Board of Directors to fix by  resolution  or resolution
providing  for the issue of  Preferred  Stock the voting  powers,  designations,
preferences and relative,  participating,  optional or other special rights, and
the  qualifications,  limitations  or  restrictions  thereof,  of the  shares of
Preferred Stock which are not fixed by the Certificate of Incorporation,  are as
follows:

                  1. The Preferred  Stock may be issued from time to time in one
         or more series,  each such series to have such distinctive  designation
         or  title  as may be  fixed  by the  Board  of  Directors  prior to the
         issuance of any shares thereof.  Each such series may differ from every
         other series already outstanding as may be determined from time to time
         by the Board of Directors  prior to the issuance of any shares thereof,
         in any or all of the following, but in no other, respects:
                           (a) The rate of dividend which the Preferred Stock of
                  any such series  shall be  entitled  to  receive,  whether the
                  dividends of such series shall be cumulative or non-cumulative
                  and,  if such  dividends  shall be  cumulative,  the date from
                  which they shall be cumulative.
                           (b)  The  right  or   obligation,   if  any,  of  the
                  corporation to redeem shares of Preferred  Stock of any series
                  and the amount per share which the Preferred Stock of any such
                  series shall be entitled to receive in case of the  redemption
                  thereof, and the right of the corporation,  if any, to reissue
                  any such shares after the same shall have been redeemed.
                          (c)  The amount  per share  which the  Preferred
                  Stock of any such series  shall be entitled to receive in case
                  of the  voluntary liquidation,  distribution  or sale of
                  assets,  dissolution or winding up of the  corporation,  or
                  in case of the involuntary liquidation , distribution  or sale
                  of assets,  dissolution or winding up of the corporation.

<PAGE>

                            (d) The right,  if any, of the holders of  Preferred
                  Stock of any such  series  to  convert  the  same  into  other
                  classes  of  stock,  and  the  terms  and  conditions  of such
                  conversion.
                           (e) The  voting  power,  if any,  of the  holders  of
                  Preferred  Stock of any series,  and the terms and  conditions
                  under which they may exercise such voting power.
                           (f) The terms of the sinking  fund or fund of similar
                  nature,  if any, to be provided for the Preferred Stock of any
                  such series.
                           The  description  of terms of the Preferred  Stock of
                  each series in respect of the foregoing  particulars  shall be
                  fixed and  determined by the Board of Directors by appropriate
                  resolution at or prior to the time of the authorization of the
                  issue of the original  shares of each such series.
     2. In case the stated  dividends  and the amounts  payable on  liquidation,
distribution or sale of assets, dissolution or winding up of the corporation are
not paid in full, the  stockholders  of all series of the Preferred  Stock shall
share ratably in the payment of dividends,  including accumulations,  if any, in
accordance  with the same which would be payable on such shares if all dividends
were declared and paid in full and in any  distribution  of assets other than by
way of  dividends,  in  accordance  with the sums which would be payable on such
distribution if all sums payable were discharged and paid in full.
                  3. The  holders of the  Preferred  Stock  shall be entitled to
         receive,  when and as declared by the Board of Directors,  out of funds
         legally available therefor,  preferential dividends in cash at, but not
         exceeding the annual rate fixed for each particular series. The holders
         of the  Preferred  Stock shall not be entitled to receive any dividends
         thereon other than dividends referred to in this Subdivision 3.
                  4. So long as any of the Preferred Stock remains  outstanding,
         in no event  shall  any  dividend  whatever,  whether  in cash or other
         property  (other than shares of Common  Stock),  be paid or declared or
         any  distribution be made on the Common Stock,  nor shall any shares of
         the Common  Stock be  purchased,  retired or  otherwise  acquired for a
         consideration  by the corporation  unless (a) the full dividends of the
         Preferred Stock for all past dividend  periods from the respective date
         or then current quarter-yearly  dividend period shall have been paid or
         declared and a sum set apart  sufficient for the payment  thereof,  and
         (b) if at any time the corporation is obligated to retire shares of any
         series of the Preferred Stock pursuant to a sinking fund or a fund of a
         similar  nature,  all arrears,  if any, in respect of the retirement of
         the  Preferred  Stock of all such  series  shall  have been made  good.
         Subject to the foregoing  provisions and not otherwise,  such dividends
         (payable in cash, stock or otherwise) as may be determined by the Board
         of Directors  may be declared and paid on the Common Stock from time to
         time out of the remaining  funds of the corporation  legally  available
         therefor,  and the Preferred Stock shall not be entitled to participate
         in any such dividend, whether payable in cash, stock or otherwise.

<PAGE>
                  5. In the event of any  liquidation,  distribution  or sale of
         assets, dissolution or winding up of the corporation, whether voluntary
         or involuntary, before any distribution or payment shall be made to the
         holders of Common  Stock,  the holders of the  Preferred  Stock of each
         series shall be entitled to be paid in cash the applicable  liquidation
         price  per share  fixed at the time of the  original  authorization  of
         issuance of shares of such respective  series,  together with a sum, in
         the case of each share of the Preferred  Stock,  computed at the annual
         dividend  on such share  became  cumulative  to the date fixed for such
         distribution  or payment date paid thereon.  If such payment shall have
         been made in full to the holders of the Preferred  Stock, the remaining
         assets  and funds of the  corporation  shall be  distributed  among the
         holders of the Common Stock according to their respective shares.
                  6.  Subject  to the  powers,  preferences  and  rights and the
         qualifications,  limitations and restrictions  thereof, with respect to
         each class of capital stock of the corporation having any preference or
         priority over the Common  Stock,  the holders of the Common Stock shall
         have and  possess  all  rights  appertaining  to  capital  stock of the
         corporation.  Holders of Common  Stock may not act by  written  consent
         without a meeting.

<PAGE>
                                                                    APPENDIX B

                             MEDTOX SCIENTIFIC, INC.
                        AMENDED ARTICLE FIFTH, SECTION 1.
                         OF CERTIFICATE OF INCORPORATION

     FIFTH:  For the  management  of the  business  and for the  conduct  of the
affairs of the Corporation, and in further definition, limitation and regulation
of the powers of the  Corporation and of its directors and  stockholders,  it is
further provided:

         1. The number of  directors of the  Corporation  shall not be less than
three nor more than twelve, the exact number within said limits to be fixed from
time to time by the vote of a majority  of the  directors  then in  office.  The
Board of Directors  shall be divided  into three  classes,  designated  Class I,
Class II and Class III, as nearly equal in number as  possible,  and the term of
office  of  Directors  of one  class  shall  expire at each  annual  meeting  of
stockholders,  and in all cases as to each Director until his successor shall be
elected and shall qualify or until his earlier resignation, removal from office,
death or  incapacity.  Additional  directorships  resulting  from an increase in
number of  Directors  shall be  apportioned  among the  classes  as  equally  as
possible. The initial term of office of Directors of Class I shall expire at the
annual  meeting of  stockholders  in 2000;  that of Class II shall expire at the
annual meeting in 2001; and that of Class III shall expire at the annual meeting
in 2002;  and in all  cases as to each  director  until his  successor  shall be
elected and shall qualify or until his earlier resignation, removal from office,
death or  incapacity.  At each  annual  meeting  of  stockholders  the number of
Directors  equal to the number of  Directors  of the class whose term expires at
the time of such  meeting  (or,  if  less,  the  number  of  Directors  properly
nominated and qualified for election)  shall be elected to hold office until the
third succeeding annual meeting of stockholders after their election.

         In case of any  vacancies,  by reason of an  increase  in the number of
directors,  resignation or otherwise,  directors to fill such vacancies shall be
elected by a majority of the directors then in office,  and any such director so
elected shall hold office until the next succeeding election of directors in the
Class to which such director is assigned.

                            MEDTOX SCIENTIFIC, INC.
                           AMENDMENTS TO ARTICLE III,
                           Sections 1 and 5 of Bylaws

[In the event that the classified  Board  proposal is approved by  shareholders,
the following conforming  amendments will be made to Article III, Sections 1 and
5 of the Bylaws]

                                   Article III
                                    Directors

         1. The  property,  affairs  and  business of the  corporation  shall be
managed by its Board of Directors consisting of not less than three (3) nor more
than twelve (12) persons.  The exact number of directors  within the maximum and
minimum limitations  specified shall be fixed from time to time by resolution of
the Board of  Directors.  The Board of  Directors  shall be  divided  into three
classes,  designated  Class I, Class II and Class III, as nearly equal in number
as

<PAGE>

possible,  and the term of office of Directors of one class shall expire at each
annual meeting of  stockholders,  and in all cases as to each Director until his
successor  shall be elected and shall qualify or until his earlier  resignation,
removal from office,  death or incapacity.  Additional  directorships  resulting
from an increase in number of Directors  shall be apportioned  among the classes
as equally as possible. The initial term of office of Directors of Class I shall
expire at the annual  meeting of  stockholders  in 2000;  that of Class II shall
expire at the annual  meeting in 2001; and that of Class III shall expire at the
annual meeting in 2002; and in all cases as to each director until his successor
shall be elected  and shall  qualify or until his earlier  resignation,  removal
from office,  death or incapacity.  At each annual meeting of  stockholders  the
number of  Directors  equal to the number of  Directors  of the class whose term
expires  at the time of such  meeting  (or,  if less,  the  number of  Directors
properly  nominated and qualified for election)  shall be elected to hold office
until the third succeeding annual meeting of stockholders  after their election.
Directors need not be stockholders.

         5. At any special meeting of the stockholders,  duly called as provided
in these Bylaws,  any director or directors may by the  affirmative  vote of the
holders of a majority  of all the shares of stock  outstanding  and  entitled to
vote for election of directors be removed from office,  but only for cause,  and
his  successor  or their  successors  may be  elected  at such  meeting;  or the
remaining  directors  may,  to the  extent  vacancies  are  not  filled  by such
election, fill any vacancy or vacancies created by such removal.

<PAGE>


                                                                     APPENDIX C
                             MEDTOX SCIENTIFIC, INC.
                     QUALIFIED EMPLOYEE STOCK PURCHASE PLAN

                  WHEREAS, MEDTOX Scientific,  Inc., a Delaware corporation (the
"Company"), adopted the Environmental Diagnostics, Inc. Qualified Employee Stock
Purchase  Plan (the  "Plan") to offer its  employees  the right to purchase  its
Common Stock, $0.15 par value per share ("Stock"), on March 13, 1986;

                  WHEREAS, the Plan was approved by the Company's shareholders
on September 11, 1986;

                  WHEREAS,  pursuant  to  Section  14 of the Plan,  the Board of
Directors  of the Company  may amend or modify the Plan at any time,  subject to
any required shareholder approval;

                  WHEREAS, the Company desires to amend and restate the Plan and
to  increase  the  number of shares  authorized  under the Plan,  subject to and
effective upon shareholder approval;

                  NOW,  THEREFORE,  pursuant to premises  and  covenants  herein
contained,  the Company  does hereby  amend and restate the Plan  subject to and
effective upon shareholder approval which shall read as follows:

SECTION 1.        EMPLOYEES ENTITLED TO PARTICIPATE.

                  An individual is eligible to participate in the Plan if (a) he
is  regularly  scheduled  to work for more than  twenty  hours per week and five
months  per  calendar  year;  (b) he is  employed  by the  Company  or any other
corporation in which the Company owns or acquires,  directly or  indirectly,  at
least 50% of the total  combined  voting power of all classes of stock,  if such
corporation   has  been  designed  as  a   participating   corporation   by  the
Administration  Committee;  and (c) he agrees to pay the  subscription  price by
payroll  deduction.  In accordance  with the  requirements of Section 423 of the
Internal  Revenue Code of 1986, as amended (the "Internal  Revenue  Code"),  all
employees  granted  subscriptions  under the Plan shall have the same rights and
privileges hereunder,  subject to the provisions of federal and state securities
laws that may effect transactions made pursuant to the Plan by certain employees
who may be deemed to be insiders of the Company.

                  It is intended  that the Plan allow for  broad-based  employee
participation  and not  discriminate in favor of highly  compensated  employees.
Accordingly, the Plan shall be administered in compliance with Section 410(b) of
the  Internal  Revenue  Code  with  regard  to  the  broad-based   participation
requirement  and Section  401(a)(4) of the Internal  Revenue Code with regard to
the nondiscrimination requirement. Accordingly, the Plan shall be interpreted in
accordance with such provisions as now written or as hereafter amended.

<PAGE>

SECTION 2.        SUBSCRIPTION PRICE.

                  The  subscription  price  hereunder shall be the lesser of (a)
85% of the fair market value of the Stock on the day the  executed  subscription
form is received  by the  Company,  or (b) 85% of the fair  market  value of the
Stock on the day the right to purchase is exercised, as provided in Section 7(A)
below.  For purposes of this Plan, the "fair market value" of the Stock shall be
determined as set forth below.

                  If the Stock is traded on a national securities exchange, then
the "fair  market  value" on a date shall be the  closing  price of the Stock on
such  exchange  based on the sale of a minimum of 100  shares of Stock;  if less
than 100 shares are traded on such date, then the fair market value shall be the
average of the high bid and low asked  prices on such date;  or if no prices are
quoted on such date,  then the fair market  value shall be the closing  price of
the Stock on such exchange based on the sale of a minimum of 100 shares of Stock
on the last prior date on which at least 100 shares were sold.

                  If the Stock is not traded on a national securities  exchange,
but is  quoted  in the  over-the-counter  market  as  reported  on the  National
Association of Securities  Dealers  Automated  Quotation  ("NASDAQ") System on a
date,  then the "fair market value" of the shares on such date shall be the last
sale price reported by the NASDAQ System or the NASDAQ  National  Market System,
as  applicable,  based on the sale of a minimum of 100 shares of Stock;  if less
than 100 shares are traded on such date, then the fair market value shall be the
average of the high bid and low asked  prices on such date as reported by NASDAQ
System or the NASDAQ National Market System, as applicable;  or if no prices are
quoted on such date,  then the fair market value shall be the last sale price of
the Stock as reported by NASDAQ  based on the sale of a minimum of 100 shares of
Stock on the last prior date on which at least 100 shares were sold.

                  If the Stock is not traded on a national  securities  exchange
or reported by NASDAQ, if any  broker-dealer  makes a market for the Stock, then
the "fair  market  value" of the  shares on a date  shall be the  average of the
highest and lowest quoted selling prices of the Stock on that date, said average
to be based on the sale of a minimum  of 100  shares of Stock;  if less than 100
shares are traded on such date, then the fair market value of the shares on such
date shall be the  average of the high bid and low asked  prices on such date in
such market; or if no prices are quoted on such date, then the fair market value
of the shares on such date shall be the average of the highest and lowest quoted
selling  prices of the Stock  based on the sale of a  minimum  of 100  shares of
Stock on the last prior date on which at least 100 shares were sold.

         If  the  Stock  is  not  traded  in  any  established   market  and  no
broker-dealer makes a market in the Stock, then the "fair market value" shall be
the fair  value  thereof  as  determined  in good  faith  by the  Administration
Committee pursuant to any appropriate method selected by the Committee.

<PAGE>

SECTION 3.        NUMBER OF SHARES AUTHORIZED.

                  The total  number of shares of Stock  authorized  to be issued
hereunder  is 150,000  shares,  which shall be newly issued  shares.  Additional
shares may be authorized to be issued  hereunder  from time to time by the Board
of Directors  of the  Company,  provided  that the  stockholders  of the Company
approve such  increase  within twelve (12) months before or after such action by
the Board of Directors.

SECTION 4.        SUBSCRIPTIONS.

                  A.       How to Subscribe.

                  Any eligible employee may subscribe hereunder by executing and
mailing or  delivering  to the  Secretary  of the Company or any  representative
designated by him a subscription form approved by the Administration  Committee.
The receipt of such  subscription form by the Company shall constitute the grant
to the employee (and the acceptance by him) of a right to purchase the number of
shares indicated on the form at the subscription  price and subject to the terms
and conditions  contained  herein,  except that no such right shall be deemed to
have been  granted  (i) during any period in which the  offering  of Stock under
this Plan does not comply with the  requirements  of the Securities Act of 1933,
as amended,  or any applicable  state  securities law, or (ii) if  subscriptions
have been  issued  for the total  number  of shares  authorized  to be issued or
transferred hereunder.

                  B.       Number of Shares for Which Employee May Subscribe.

                  The maximum  number of shares  which an eligible  employee may
subscribe for under the Plan shall be subject to such  limitations  from time to
time established by the Administration Committee. The maximum number shall apply
equally to all eligible  participants.  An employee may  subscribe for less than
the  maximum  number of shares and may  successively  subscribe  for  additional
shares  until he has  subscribed  for the  maximum  number of shares  permitted;
provided,  however,  that the  receipt of each new  subscription  by the Company
shall be considered to be a separate  grant of a right to purchase the number of
shares indicated on the subscription  form for all purposes  hereunder and shall
be subject to the waiting periods provided below.

                  C.       Waiting Period.

                  An  employee  who has  subscribed  for less  than the  maximum
number of shares may not subscribe for additional shares unless (i) at least six
(6) months have elapsed since the date of receipt of his last prior subscription
form, (ii) such employee has withdrawn a prior  subscription  and at least three
(3) months  have  elapsed  since the date of his last  withdrawal,  or (iii) all
prior  subscriptions  by the employee to acquire shares under the Plan have been
paid in full.

<PAGE>

                  D.       Limitations on Subscriptions.

                  Notwithstanding any provision herein, an employee shall not be
entitled  to  subscribe   hereunder  if,   immediately   after  receipt  of  the
subscription form by the Company, such employee owns stock possessing 5% or more
of the  total  combined  voting  power or value of all  classes  of stock of his
employer corporation or its parent or any subsidiary  corporation.  For purposes
of the preceding  sentence,  the rules of Section 424(d) of the Internal Revenue
Code shall apply in determining  the stock  ownership of an employee,  and stock
which the employee may purchase  under  outstanding  subscriptions  hereunder or
under any  other  stock  option  plan  shall be  treated  as stock  owned by the
employee.  Notwithstanding any provision herein, if the rights of an employee to
purchase  stock  under all stock  purchase  plans (to which  Section  423 of the
Internal Revenue Code is applicable) of his employer  corporation and its parent
and  subsidiary  corporations  accrue  (within the meaning of and subject to the
rules  contained in Section  423(b)(8) of the Internal  Revenue  Code) at a rate
which exceeds $25,000 of fair market value of such stock (determined at the time
the subscription form is received by the Company) for any calendar year in which
such subscription is outstanding at any time, such employee's subscription shall
be reduced,  in the manner prescribed by the Administration  Committee,  so that
the  employee's  rights do not  accrue at a rate which  exceeds  $25,000 of fair
market value of such stock for such calendar year as described above.

SECTION 5.        PAYMENT OF SUBSCRIPTION PRICE.

                  A.       Payroll Deductions.

                  Payment of the subscription price under the Plan shall be made
by payroll deductions pursuant to such procedures and limitations as established
from  time  to time  by the  Administration  Committee.  Beginning  on the  date
specified in the  subscription  form, or as soon as practicable  for the Company
thereafter,  but in no event  later  than two months  after the date  specified,
deductions  for  payment  of the  subscription  prices  shall be made  from each
regular   payroll  check  for  a   participating   employee  until  all  of  his
subscriptions  have been  paid or  withdrawn,  but in no event  may the  payment
period be  structured  so that the date of  exercise of the  purchase  rights as
provided in Section 7(A) hereof exceeds  twenty-seven  (27) months from the date
of grant of such purchase rights. If local law prohibits payroll  deductions for
such purpose,  any alternative method approved by the  Administration  Committee
may be substituted.  All payments shall be forwarded monthly to the Treasurer of
the Company.

                  B.       Prepayment of Subscription Price.

                  No  prepayment  of  subscription  prices may be made  except
as  provided in Sections 9 and 14 below.

<PAGE>

SECTION 6.        SUBSCRIPTION ACCOUNTS.

                  A subscription account shall be created for each participating
employee and all amounts  withheld  from his  compensation  shall be credited to
such  account.  Amounts  credited to such  accounts  shall be available  for the
general use of the  Company.  The Company will provide a statement at least once
each year of the remaining balance in each participating employee's account.

SECTION 7.        ISSUANCE OF STOCK.

                  A.       Completion of Payment for 100 Share Unit.

                  When the subscription account of any employee contains
an amount  equal to at least 100  shares or any  lesser  number of shares  under
subscription  (on a first in first out basis)  multiplied  by 85% of fair market
value of the Stock on the day the executed  subscription form is received by the
Company,  the employee  shall be deemed to have  exercised the right to purchase
100 or such lesser number of shares.  Thereafter the employee's account shall be
debited for the subscription price (as defined in Section 2) of such shares, and
the Company shall issue or cause to be transferred to the employee a certificate
for such shares within a reasonable time. If the fair market value on the day of
exercise is below that on the day the executed  subscription was received by the
Company, the employee's subscription account shall be charged for only an amount
equal to 85% of the fair market value on such  exercise  date of the shares then
acquired  and the  balance in the  account  shall be held to pay for  additional
shares under subscription,  if any, or returned if no additional shares are then
under  subscription.  The  number of  shares  purchased  shall in every  case be
determined solely by reference to the fair market value on the date the executed
subscription form is received by the Company, and may not be increased by reason
of any subsequent decline in fair market value.

                  B.       Rights as Stockholders.

                  Nothing  in this  Plan  shall  confer  upon any  participating
employee  any  rights  as a  stockholder  except  the right to be issued a stock
certificate for fully-paid  shares of Stock as provided  herein,  and until such
issuance,  the participating  employee shall not be deemed the owner of any such
shares for any purpose.

                  C.       Extension of Time for Delivery.

                  The time of issuance  and  delivery of shares may be postponed
for such  period as may be required  to comply  with  registration  requirements
under the Securities Act of 1933, as amended,  listing requirements of any stock
exchange upon which Stock may be listed, if any, and the requirements  under any
other law or regulation applicable to the issuance or transfer of such shares.

<PAGE>

SECTION 8.        WITHDRAWAL OF SUBSCRIPTIONS.

                  Any  employee  may  withdraw  any  subscription  upon filing a
notice  thereof with the person  designated  by and on the form  approved by the
Administration  Committee.  Said subscription  shall thereupon be canceled as to
all shares with respect to which the right to purchase has not been exercised as
provided in Section 7(A) above. If the employee  withdraws all his subscriptions
hereunder,  he will be entitled  to receive  the  balance of his account  within
thirty (30) days after the receipt of such  notice.  If an employee  withdraws a
subscription,  he shall not be entitled to subscribe for  additional  shares for
three (3) months after the last such withdrawal.

SECTION 9.        TERMINATION OF EMPLOYMENT.

                  A.       Death, Permanent Disability and Retirement.

                  If a participating  employee's  services are terminated before
his  subscription  is fully  paid,  because of death,  permanent  disability  or
retirement at age 55 or thereafter,  the employee (or, in the case of death, his
estate) may, at his option,  within three (3) months  thereafter  in the case of
such  permanent  disability or retirement or within twelve months  thereafter in
the case of death,  prepay his  subscription in whole or in part, or receive the
balance of his  subscription  account in  satisfaction  of all rights  under the
Plan.

                  B.       Other Termination of Service.

                  If a participating  employee's  services are terminated before
his  subscription  is fully paid,  for any reason  other than  death,  permanent
disability or retirement at age 55 or thereafter,  the employee will be entitled
to receive only the balance of his  subscription  account.  Such  payment  shall
constitute  satisfaction  of all his rights under this Plan,  and all  remaining
subscriptions hereunder shall be deemed withdrawn.

                  C.       Temporary Absence.

                  Any  employee  whose name is taken off the regular  payroll by
reason of leave of absence,  temporary layoff, or through temporary  disability,
may at his option (i)  withdraw  his  subscriptions  hereunder  and  receive the
amount to which he would be entitled if his  services  were  terminated  for any
reason as provided in  subparagraph  (B) hereof,  or (ii) make regular  periodic
payments to the  Treasurer  of the  Company in an amount  equal to the sum which
would have been withheld had he continued on the regular payroll.

<PAGE>

SECTION 10.       RIGHTS NOT TRANSFERABLE.

                  Neither the right of an employee to purchase shares hereunder,
nor his  account  balance,  shall be  transferable  by the  employee  (by way of
assignment,  pledge,  or  otherwise)  except by will or the laws of descent  and
distribution,  and neither  such right nor such  balance  shall be liable for or
subject to the debts or liabilities of such employee.  If any action is taken by
the employee to so transfer  such right or balance,  such action shall be deemed
to constitute a withdrawal of the subscription involved.

SECTION 11.       ADMINISTRATION COMMITTEE.

     This Plan shall be administered by an Administration  Committee  consisting
of two or more non-employee  directors of the Company, who shall be appointed by
its Board of Directors.  The Committee,  or a majority  thereof,  shall have the
authority to interpret this Plan, to prescribe rules and regulations thereunder,
and to make all other  determinations  necessary  or  advisable  for the  Plan's
administration.  The members of the Committee shall serve until their successors
have been appointed by the Board of Directors.

SECTION 12.       ADJUSTMENTS.

                  In the event of a  dividend  payable  in  Common  Stock of the
Company or a subdivision or combination of the Common Stock of the Company,  the
number of shares  offered under this Plan,  and the number of shares  offered by
options   outstanding   under  the  Plan,   shall  be   increased  or  decreased
proportionately,   as  the  case  may  be,   without  change  in  the  aggregate
subscription price for such shares. In case the Company is reorganized or merged
or consolidated with another corporation,  appropriate  provisions shall be made
for the protection and continuation of any outstanding  subscriptions  under the
Plan by the  substitution  on an  equitable  basis  determined  by the  Board of
Directors of appropriate stock or other securities of the reorganized, merged or
consolidated corporation which will be issuable in respect of the Stock.

SECTION 13.       TAX ON ADDITIONAL COMPENSATION.

                  In the event that the  issuance  or  disposition  of any Stock
subscribed  hereunder  results in additional  compensation  to an employee under
federal,  state or foreign laws which  require that the tax thereon be withheld,
the Company and its  subsidiaries  will deduct from the employee's  compensation
the  amount  required  for  such  withholding.  Until  such tax is  withheld  or
otherwise  paid by the employee to the  Company,  Stock paid for but unissued or
undelivered hereunder will be held by the Company in issued form as security for
the amount required to be withheld.

<PAGE>

SECTION 14.       TERM OF PLAN.

                  This amended and restated  Plan is subject to and shall become
effective  upon  approval  by the  stockholders  of the  Company.  The  Board of
Directors may  terminate the Plan at any time,  and may amend the Plan from time
to time,  subject to any approval of the stockholders of the Company that may be
required in order that the Plan shall  continue to qualify  under Section 423 of
the Internal Revenue Code. Upon termination of the Plan, participating employees
shall,  in the  discretion  of the Board of  Directors,  either be  permitted to
complete  unpaid  subscriptions  in a manner  determined  by the  Administration
Committee  or shall be entitled  to receive  the  balance in their  subscription
account in satisfaction of all rights under the Plan.

SECTION 15.       INTERPRETATION OF THE PLAN.

                  It is  intended  that this Plan shall meet and comply with all
the  requirements  of Section  423 of the  Internal  Revenue  Code,  and related
Sections.  The Plan and the  terms  used  herein  shall  be  interpreted  by the
Administration  Committee in such manner as to carry out such intention,  and in
particular, the grant of a right to purchase shares hereunder shall be deemed to
constitute  the grant of an option  under  Section 423 of the  Internal  Revenue
Code,  and the  exercise of the right to purchase  hereunder  shall be deemed to
constitute the exercise of an option under such Section.

         IN WITNESS  WHEREOF,  the Company has caused  these  instruments  to be
executed by its duly  authorized  officers and its corporate seal to be hereunto
affixed, all as of the day and year first above written.

                                            MEDTOX SCIENTIFIC, INC.
ATTEST:

___________________________                 By:________________________________
Secretary                                      President

(Corporate Seal)


<PAGE>


                                                                    APPENDIX D
                             MEDTOX SCIENTIFIC, INC.
                         ANNUAL MEETING OF STOCKHOLDERS
                               SEPTEMBER 16, 1999

              This Proxy is Solicited on Behalf of the Board of Directors


         The undersigned stockholder of MEDTOX Scientific,  Inc. (the "Company")
hereby  appoints Harry G. McCoy and Richard J. Braun,  and each or either one of
them, the true and lawful attorneys, agents, and proxies of the undersigned with
full power of substitution for and in the name of the  undersigned,  to vote all
the shares of Common Stock of MEDTOX SCIENTIFIC,  Inc. which the undersigned may
be entitled to vote at the Annual Meeting of  Stockholders  of the Company to be
held at the Sheraton  Minneapolis  Metrodome,  located at 1330 Industrial Blvd.,
Minneapolis,  Minnesota on or about Thursday,  September 16, 1999, at 2:00 P.M.,
Central Time, and at any and all adjournments thereof, with all the powers which
the undersigned would possess if personally present, for the following purposes:



                      (Continued and to be signed on the other side)


<PAGE>


Please mark your
votes as in this example                           FOR     AGAINST     ABSTAIN

For   Withheld

Nominees: Harry G. McCoy, Samuel         2.  The adoption of an Amendment
C. Powell, Richard J. Braun,             to    the     Certificate     of
James W. Hansen and Miles E. Efron       Incorporation to increase the numberof
                                         authorized common stock as set forth
                                         in the Proxy Statement.

1.  Election of Directors                3.  The adoption of an Amendment
                                         to the Certificate of Incorporation
                                         to provide for the classification of
                                         the Board of  Directors as set forth
                                         in the Proxy Statement.

                                         4.    The    adoption    of   an
                                         amendment to the  Employee   Stock
                                         Purchase Plan as set forth in the
                                         Proxy Statement

                                         5.  Considering  and acting upon any
                                         other    matters    which    may
                                         properly come before   the   meeting
                                         or  any adjournment thereof.

For, except vote withheld from the following nominees:
______________________

[  ]  Please check box if you intend to attend the meeting in person.


This Proxy  will be voted for the choices specified.  If no choice is  specified
with  respect to the  election  of  Directors,  this Proxy will be voted FOR the
election of the Directors  listed.  If no choice is specified for Proposals 2, 3
and 4, this Proxy will be voted FOR Proposals 2, 3 and 4.


The undersigned hereby acknowledges  receipt of the Notice of Annual Meeting and
Proxy Statement dated August 9, 1999.


PLEASE MARK, SIGN, DATE AND MAIL  THIS PROXY IN THE ENVELOPE PROVIDED.

SIGNATURE(S) ____________________________                    Dated:______, 1999

NOTE: Please sign exactly as name appears hereon. Joint owners should each sign.
When signing as attorney,  executor,  administrator,  trustee,  guardian, please
give your full title as such.




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