MEDTOX SCIENTIFIC INC
DEF 14A, 1999-01-19
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                            SCHEDULE 14A INFORMATION

Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934
                                (Amendment No. )

Filed by the Registrant  [X]
Filed by a Party other than the Registrant [  ]

Check the appropriate box:

   
[ ]      Preliminary Proxy Statement
[ ]      Confidential,  for  Use  of the  Commission  Only  (as  permitted  by
         Rule 14a-6(e)(2)) 
[X]      Definitive Proxy Statement 
[ ]      Definitive  Additional Materials
[ ]      Soliciting Material Pursuant to Section 240.14a-11(c) or Section 
         240.14a-12
    

                             MEDTOX SCIENTIFIC, Inc.
                (Name of Registrant as Specified In Its Charter)

                    (Name of Person(s) Filing Proxy Statement
                          if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):

   
[ ]      $125 per Exchange Act Rules 0-11(c)(1)(ii), 14a-6(i)(2).
[ ]      $500 per each party to the controversy pursuant to Exchange Act Rule 
         14a-6(i)(3).
[ ]      Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 
         0-11.
         1)       Title of each class of securities to which transaction
         applies:
         2)       Aggregate number of securities to which transaction applies:
         3) Per unit price or other  underlying  value of  transaction  computed
         pursuant to Exchange  Act Rule  0-11;1 4)  Proposed  maximum  aggregate
         value of transaction:
                  1 Set forth the amount on which the  filing fee is  calculated
and  state  how it was  determined.  
[X]     Fee Paid  Previously  with  preliminary
        materials.  
[ ]     Check  box if any  part  of the fee is  offset  as  provided  by
        Exchange Act Rule  0-11(a)(2)  and identify the filing for which the  
        offsetting fee was paid previously.  Identify the previous filing by 
        registration statement number, or the Form or Schedule and the date of
        its filing.
         1)       Amount Previously Paid:
         2)       Form, Schedule or Registration Statement No:
         3)       Filing Party:
         Date Filed:
    



<PAGE>


   
                             MEDTOX SCIENTIFIC, INC.
                             402 West County Road D
                            St. Paul, Minnesota 55112
    


                    NOTICE OF SPECIAL MEETING OF STOCKHOLDERS
                         To Be Held on February 22, 1999


         NOTICE  IS HEREBY  GIVEN  that a Special  Meeting  of the  stockholders
("Special  Meeting") of MEDTOX  SCIENTIFIC,  INC., a Delaware  corporation  (the
"Company"),  will  be held at The  Residence  Inn,  2985  Centre  Pointe  Drive,
Roseville,  Minnesota 55113 on Monday,  February 22, 1999 at 9:00 a.m. (CST) for
the following purposes:

         1. To adopt and approve an amendment to the  Company's  Certificate  of
Incorporation  providing for a one-for-twenty reverse stock split of outstanding
Common Stock of the Company; and

         2. To consider and act upon any other  matters  which may properly come
before the meeting or any adjournment thereof.

         In accordance  with the  provisions  of the Bylaws of the Company,  the
Board of  Directors  has fixed the close of  business  on January 7, 1999 as the
record date for the  determination  of the holders of the shares of Common Stock
entitled to notice of, and to vote at, the Special Meeting.

         Your attention is directed to the accompanying Proxy Statement.

         Stockholders are requested to date, sign and mail the enclosed Proxy as
promptly  as  possible,  whether  or not they  expect to attend  the  meeting in
person.

                                 By Order of the Board of  Directors,



                                 Harry G. McCoy
                                 Chairman of the Board and President

   
St. Paul, Minnesota
January 19, 1999
    


<PAGE>



                             MEDTOX SCIENTIFIC INC.
                             402 West County Road D
                            St. Paul, Minnesota 55112

   
                                PROXY STATEMENT
    


                         SPECIAL MEETING OF STOCKHOLDERS
                                February 22, 1999


                                     PROXIES

         The enclosed  proxy (the  "Proxy") is solicited by and on behalf of the
Board of  Directors of MEDTOX  SCIENTIFIC,  INC.,  a Delaware  corporation  (the
"Company"), for use at a special meeting of stockholders (the "Special Meeting")
and at any and all adjournments thereof. Any stockholder has the power to revoke
his or her Proxy at any time  before it is voted.  A Proxy may be revoked (1) by
delivery of written  notice of revocation to the Secretary of the Company at its
principal office, 402 West County Road D, St. Paul,  Minnesota 55112, (2) by the
execution of a subsequent  Proxy and presentment of such subsequent Proxy at the
Special  Meeting  or (3) by  attendance  at the  Special  Meeting  and voting in
person. This solicitation is being made by use of the mails and the cost thereof
will be borne by the Company.  Shares represented by valid Proxies will be voted
in  accordance  with  the  instructions  indicated  thereon.   Unless  otherwise
directed,  votes will be cast FOR  Proposal 1  concerning  the  Amendment to the
Company's  Certificate of Incorporation  providing for a one-for-twenty  reverse
stock split.

         The costs of solicitation  of proxies will be borne by the Company.  In
addition to use of mails, proxies may be solicited  personally,  or by telephone
by one or  more of the  regular  personnel  of the  Company  without  additional
compensation.  The  Company  expects  to  pay  an  independent  proxy  solicitor
approximately  $7,500  as  compensation  for the  solicitation  of  proxies.  In
addition,  the Company may reimburse brokers and other custodians,  nominees and
fiduciaries for their expenses for sending proxy material to beneficial  owners,
in accordance with Securities and Exchange Commission regulations.

   
     The Company  anticipates  mailing proxy materials to stockholders of record
as of January 7, 1999 (the "Stockholders") on or about January 19, 1999.
    

                            OUTSTANDING VOTING STOCK

         Only holders of record of the Company's  Common  Stock,  par value $.15
per share (the "Common Stock"),  at the close of business on January 7, 1999 are
entitled to vote on matters to be presented at the Special  Meeting.  Each share
of Common  Stock is entitled to one vote with respect to all such  matters.  The
number of shares of Common Stock  outstanding  and entitled to vote at the close
of business on January 7, 1999 was 58,029,594.

<PAGE>

                          VOTE AND QUORUM REQUIREMENTS

         The  presence  in person or by Proxy of holders  of a  majority  of the
outstanding  shares of Common  Stock is  required  for there to exist the quorum
needed to transact  business at the Special  Meeting.  If,  initially,  a quorum
should not be present,  the Special  Meeting may be adjourned  from time to time
until a quorum is obtained.

         The affirmative vote of a majority of the outstanding  shares of Common
Stock is required for approval of the proposed  amendment to the  Certificate of
Incorporation of the Company providing for the reverse stock split.  Abstentions
and  "broker   non-votes"  (as  defined  below)  are  counted  for  purposes  of
determining  whether a quorum is present,  but do not represent  votes cast with
respect to any  proposal.  "Broker  non-votes"  are  shares  held by a broker or
nominee for which an executed  proxy is  received  by the  Company,  but are not
voted as to one or more proposals  because  instructions  have not been received
from the beneficial owners or persons entitled to vote and the broker or nominee
does not have discretionary voting power.

         An independent party will receive and tabulate all proxies and ballots,
and such  independent  party and certain  other team members of the Company will
act as voting inspectors at the Special Meeting.

<PAGE>

                        COMMON STOCK OWNERSHIP OF CERTAIN
                        BENEFICIAL OWNERS AND MANAGEMENT

         The following table sets forth information  available to the Company as
of January 7, 1999 regarding the beneficial ownership of the Common Stock by (i)
each person known by the Company to beneficially own more than five percent (5%)
of the  outstanding  Common  Stock,  (ii) each of the  Directors of the Company,
(iii) the Chief Executive Officer and all executive  officers whose compensation
is $100,000 or greater,  and (iv) all  executive  officers and  Directors of the
Company as a group:

<TABLE>
<CAPTION>


Name                                          Number of Shares Beneficially Owned          Percent of Common Stock Outstanding
<S>                                                              <C>                                       <C>               
Executive Officers and Directors:
Harry G. McCoy, Pharm. D.                                           3,860,569 (1)                             6.48%
Chairman and President
Richard J. Braun                                                      768,602 (2)                             1.29%
Chief Executive Officer and Director
Samuel C. Powell, Ph.D., Director                                   1,128,034 (3)                             1.90%
James W. Hansen, Director                                              90,277 (4)                                 *
Miles E. Efron, Director                                               84,722 (5)                                 *
Kevin J. Wiersma, Controller and Secretary                             39,996 (6)                                 *
All Directors and Executive Officers As a                           5,972,200 (7)                            10.02%
Group (6 in number)
</TABLE>

*        Less than one percent (1%)

(1)      Includes 693,602 shares of Common Stock issuable under options which 
         are or which will become exercisable within the next 60 days.

(2)      Includes 693,602 shares of Common Stock issuable under options which 
         are or which will become exercisable within the next 60 days.

(3)      Includes  76,389  shares of Common  Stock  issuable  under  options and
         32,679  shares of Common Stock  issuable  under  Common Stock  Purchase
         Warrants which are or will become exercisable within the next 60 days.

<PAGE>

(4)      Includes 40,277 shares of Common Stock issuable under options which 
         are or which will become exercisable within the next 60 days.

(5)      Includes 34,722 shares of Common Stock issuable under options which 
         are or which will become exercisable within the next 60 days.

(6)      Includes 35,996 shares of Common Stock issuable under options which 
         are or will become exercisable within the next 60 days.

(7)      Includes 1,607,267 shares of Common Stock issuable under options or 
         warrants which are or will become exercisable within the next 60 days.


                   APPROVAL OF THE REVERSE SPLIT - Proposal 1
                   THE BOARD RECOMMENDS A VOTE FOR PROPOSAL 1


         The Board of Directors  of the Company has  unanimously  approved,  and
recommends that stockholders  approve, an amendment to the Company's Certificate
of  Incorporation  to effect a reverse split of the  Company's  Common Stock and
make a  corresponding  reduction  in the  authorized  number of shares of Common
Stock which the Company may issue (such actions  collectively  being referred to
as the "Reverse Split").  The Reverse Split, if approved by stockholders,  would
cause all issued and  outstanding  shares of the  Company's  Common  Stock to be
split, on a reverse basis,  one-for-twenty (i.e., stockholders would receive one
share of Common Stock for every twenty  shares held by them prior to the Reverse
Split).  If the Reverse  Split is approved at the Special  Meeting,  the Company
intends to file  documents  to effect the Reverse  Split with the  Secretary  of
State of Delaware as soon as practicable  thereafter,  upon which filing it will
be  effective.  As  described  below,  the  primary  objective  of the  Board in
effecting  the Reverse  Split is to increase  the per share  market price of the
Common Stock, and the Reverse Split will be effective on the date such documents
are filed (the "Effective Date").

         As part of the Reverse Split,  Article V, Section 1 of the  Certificate
of Incorporation would be amended to decrease the authorized number of shares of
capital  stock which the Company may issue from  76,000,000  shares to 4,750,000
shares,  3,750,000 of which shall be Common Stock,  and 1,000,000 of which shall
be Preferred Stock.

         The primary objective of the Reverse Split is to increase the per share
market price of the Common Stock.  The Company has engaged in  discussions  with
the  American  Stock  Exchange  ("AMEX")  regarding  the  trading  price  of the
Company's  Common  Stock.  The AMEX  requires a minimum  stock price of at least
$3.00 per share for initial  listing  and may delist a stock  which  trades at a
lower  price.  The  Company's  Common  Stock has  traded  below  $1.00 per share
throughout  1997  and  1998.  Although  the  AMEX  has not  commenced  delisting
procedures with respect to the Common Stock, it has recommended that the Company
take  action to comply with the AMEX's  minimum  price  rules.  A failure by the
Company to increase  the price of the Common  Stock could result in delisting of
the Common Stock by the AMEX.

<PAGE>

         A delisting of the Common Stock would have a number of adverse  effects
on the Company's stockholders.  Availability of current market price information
for the Common Stock and news coverage of the Company will be limited. Delisting
may have the effect of restricting  investors'  interest in the Common Stock and
may have a  material  adverse  effect on the  trading  market and prices for the
Common Stock as well as the Company's ability to issue additional  securities or
to secure  additional  financing.  Because of the adverse  impact on the trading
market of the Common Stock and the potential loss of effective  trading markets,
the volatility of the Common Stock may be increased.

         In addition, stocks with low per share prices are subject to additional
federal  and state  regulatory  requirements.  Because  the market  price of the
Common  Stock is less than $5 per  share,  the  Common  Stock  cannot be used as
collateral for margin loans.  In addition,  Common Stock priced less than $5 per
share is deemed a "penny  stock" under  federal  securities  laws,  resulting in
application  of additional  regulatory  restrictions.  Although the price of the
Common  Stock is less than $5 per share,  the Company  does not believe that its
Common  Stock is a penny  stock  under  federal  securities  laws,  because  the
Company's  net  tangible  assets  exceed the  required  threshold of $4 million.
However,  there is no assurance  that the Company will  continue to meet the net
tangible assets  requirement or other  exemptions from the definition of a penny
stock in the  future.  If the price of the  Common  Stock can be  maintained  at
approximately $5.00 per share, the number of institutional  investors interested
in  purchasing  Common  Stock is likely to  increase.  This  could  improve  the
liquidity of the Common Stock for all stockholders.

         If the  Reverse  Split is not  approved  by  stockholders,  the Company
believes  that the Common Stock will not be eligible to continue to be traded on
the American  Stock  Exchange.  Similarly,  the Common Stock likely would not be
eligible to be traded on the Nasdaq  National  Market System or the Nasdaq Small
Cap Market  because the  Company is not  currently  able to meet  certain of the
Nasdaq's  initial  listing  requirements.  In  particular,  the initial  listing
requirement  of the  Nasdaq  National  Market is a  minimum  bid price of $5 per
share,  and the initial listing  requirement of the Nasdaq Small Cap Market is a
minimum bid price of $4 per share.

         For the foregoing reasons, the Board of Directors has determined that a
recapitalization through the Reverse Split would be in the best interests of the
Company and its stockholders,  and recommends  stockholders  approve the Reverse
Split.

Effects of the Reverse Split

     General  Effects.  The  principal  effect of the Reverse  Split would be to
decrease  the  number of  outstanding  shares  of the  Company's  Common  Stock.
Specifically,  the 58,029,594  shares of Common Stock issued and  outstanding on
the Record  Date would,  as a result of the Reverse  Split,  be  converted  into
approximately  2,901,480  shares  of  Common  Stock  (with  the  precise  number
depending upon the extent of fractional shares resulting from the Reverse Split,
which will be  converted  to cash  based  upon the  market  price for a share of
Common Stock on the trading day prior to  implementation  of the Reverse Split).
The number of shares of Common Stock  authorized  for issuance by the  Company's
Certificate   of   Incorporation   following   the   Reverse   Split   would  be
proportionately   adjusted   from   75,000,000   shares  to  3,750,000   shares.
Accordingly, after the Reverse Split, there would be approximately 848,520 "new"
(or  post-Reverse  Split)  shares of Common Stock ("New  Shares")  available for
issuance by the Company.

<PAGE>

         Effect on Market for Common  Stock.  On  January 4, 1999,  the  closing
price of the  Company's  Common Stock as quoted on the AMEX was $0.25 per share.
By decreasing the number of shares of Common Stock otherwise outstanding without
altering the  aggregate  economic  interest in the Company  represented  by such
shares,  the Board  believes  that the per share market price for the  Company's
Common Stock will be increased in excess of the minimum $1.00 bid price required
for inclusion  continued  listing of shares on the AMEX.  Based on the $0.25 per
share closing price on January 4, 1999 and applying the Reverse  Split,  the per
share  price  of the  Common  Stock  would  have  been  $5.00.  There  can be no
assurance, however, that the per share price would remain at that level.

         Effect on Stock  Options and  Warrants.  The total  number of shares of
Common Stock  issuable upon the exercise of options and warrants to acquire such
shares,  and the exercise price  thereof,  shall be  proportionally  adjusted to
reflect the Reverse Split.

         Effect under the Company's Rights Plan. Following the implementation of
the  Reverse  Split,  each  share of  Common  Stock  will  continue  to have one
preferred  share purchase right (a "Right")  associated  with it;  however,  the
number of shares of  Preferred  Stock  issuable  upon the exercise of each Right
shall be proportionally  adjusted to reflect the Reverse Split (i.e.,  following
the effectiveness of the Reverse Split, each Right, under certain circumstances,
would  be  eligible  to  purchase  up to  twenty  one-hundredths  of a share  of
Preferred Stock).

     Changes  in  Stockholders'  Equity.  The  Reverse  Split  would  reduce the
Company's  stated  capital,  which consists of the par value per share of Common
Stock multiplied by the number of such shares outstanding, from the amount which
would otherwise  exist (assuming the share amounts set forth above,  the Reverse
Split would reduce the Company's  stated  capital by  approximately  8,269,217).
Although the par value of Common Stock would remain at $0.15 per share following
the Reverse  Split,  stated  capital  would be  decreased  because the number of
shares outstanding would be reduced.  Correspondingly,  the Company's additional
paid-in capital, which consists of the difference between its stated capital and
the  aggregate  amount  paid  to the  Company  upon  its  issuance  of all  then
outstanding shares of Common Stock, would be increased.

         Appraisal  Rights.  Pursuant to the Delaware General  Corporate Law, 
the Company's  stockholders are not entitled to appraisal rights with respect 
to the Reverse Split.

         Disadvantages.  The Company  believes  that, as a result of the Reverse
Split,  certain  shareholders  may incur  increased  expenses in selling odd-lot
shares of the Company's Common Stock.

<PAGE>

Fractional Shares

         No scrip or fractional Shares will be issued as a result of the Reverse
Split,  and  fractional  share  interests will not entitle the holder thereof to
exercise any right of a  stockholder  with respect  thereto.  In lieu of issuing
certificates  evidencing  fractional shares,  each stockholder whose holdings on
the  Effective  Date are not evenly  divisible  by 20 will be given the  option,
exercisable  within 60 days, of either: (i) selling to other stockholders of the
Company through the Company's  transfer agent,  American Stock Transfer & Trust,
Inc. (the "Exchange  Agent") his or her fractional  share interest at a price in
cash equal to the average of the reported  closing  prices for the shares on the
AMEX for the ten trading days  immediately  preceding  the  Effective  Date (the
"Average  Selling  Price")  per  each  1/20 of a share  of New  Shares;  or (ii)
purchasing  from other  Stockholders  through the Exchange  Agent, at a price in
cash equal to the Average  Selling Price per each 1/20 of a share of New Shares,
a sufficient  fractional  share  interest to "round-up" to a full New Share (and
thereby receive certificates  representing whole New Shares in exchange for such
fractional share interests).

         The Exchange Agent will act as agent for the stockholders in connection
with the  purchase and sale of  fractional  share  interests  for the purpose of
combining such interest into whole shares. The Company will not solicit purchase
or sale orders for fractional share interests.  The transmittal form, which will
be sent to  stockholders  after the Reverse  Split becomes  effective,  will ask
stockholders  to designate  whether he or she wishes to (i) sell any  fractional
share  interest or (ii)  purchase a sufficient  fractional  share  interest from
other  stockholders to round-up his or her fractional  share interest to a whole
New Share.

         The  Exchange  Agent  will,  based on the order of  receipt,  match the
transmittal forms of stockholders wishing to purchase fractional share interests
with those of stockholders  wishing to sell their  fractional  share  interests.
Accordingly,  if stockholders  wish to purchase more fractional  share interests
than those that have been offered for sale, the desire of some  stockholders  to
purchase  additional  fractional  share  interests will not be met.  Although no
assurances  can be given,  the Company  believes it likely that all  requests to
purchase a fractional share interest will be satisfied. Stockholders will not be
permitted to purchase a larger  fractional  share  interest than is necessary to
round-up to the next highest whole number of New Shares.

         The  period  during  which  stockholders  will  be  able  to  make  the
aforementioned  election  will  expire 60 days after the  transmittal  forms are
mailed to stockholders.  Any stockholder  whose transmittal form is not received
by the Exchange  Agent within such period will be deemed to have elected to sell
any fractional share interest held by him or her. Any fractional share interests
not purchased by other stockholders will be purchased by the Company.

Federal Income Tax Consequences

         The following  summary of the federal  income tax  consequences  of the
Reverse Split is based on current law,  including  the Internal  Revenue Code of
1986, as amended, and is for general information only. The tax treatment for any
stockholder may vary depending upon the particular  facts and  circumstances  of
such  stockholder.   Certain   stockholders,   including  insurance   companies,
tax-exempt organizations, financial institutions,  broker-dealers,  non-resident
aliens,  foreign  corporations  and persons who do not hold Common  Stock of the
Company as a capital asset, may be subject to special rules not discussed below.

<PAGE>

Accordingly, each stockholder should consult his or her tax advisor to determine
the particular tax  consequences  to him or her of the Reverse Split,  including
the application and effect of federal,  state, local or foreign income taxes and
other laws.

         The receipt of whole New Shares  (excluding  fractional  New Shares) in
the  Reverse  Split  should be  non-taxable  for  federal  income tax  purposes.
Consequently,  a stockholder receiving New Shares will not recognize either gain
or loss, or any other type of income,  with respect to whole New Shares received
as a  result  of  the  Reverse  Split.  In  addition,  the  tax  basis  of  such
stockholder's  shares of Common Stock prior to the Reverse Split will carry over
as the tax basis of the stockholder's New Shares.  The holding period of the New
Shares should also include the stockholder's  holding period of the Common Stock
prior to the Reverse  Split,  provided  that such  Common  Stock was held by the
stockholder as a capital asset on the effective date of the Reverse Split.

         Any  stockholder  who receives  cash in lieu of a fractional  New Share
pursuant  to the  Reverse  Split  will  recognize  gain  or  loss  equal  to the
difference  between the amount of cash received and the portion of the aggregate
tax basis in his or her shares of Common Stock  allocable to such fractional New
Share.  If the  shares of  Common  Stock  were  held as a  capital  asset on the
effective date of the Reverse Split Effective Date, then the stockholder's  gain
or loss  will be a capital  gain or loss.  Such  capital  gain or loss will be a
long-term  capital  gain or loss if the  stockholder's  holding  period  for the
shares of Common Stock is longer than eighteen months, a short-term capital gain
or loss if the  stockholder's  holding  period  is  twelve  months  or less  and
mid-term gain or loss if the stockholder's  holding period is longer than twelve
months and less than eighteen months.

         Based on certain  exceptions  contained  in  regulations  issued by the
Internal  Revenue  Service,  the  Company  does  not  believe  that  it  or  its
stockholders would be subject to backup  withholding or informational  reporting
with respect to cash distributed in lieu of fractional New Shares.

Exchange Of Shares

          On or after the effective  date of the Reverse Split  Effective  Date,
the Company  will mail to each  stockholder  of record a letter of  transmittal.
Stockholders will be able to receive a certificate  representing New Shares and,
if applicable,  cash in lieu of a fractional New Share only by  transmitting  to
the Exchange Agent such stockholder's stock  certificate(s) for shares of Common
Stock  outstanding  prior to the  Reverse  Split,  together  with  the  properly
executed and completed letter of transmittal,  and such evidence of ownership of
such  shares  as  the  Company  may  require.   Stockholders  will  not  receive
certificates for New Shares unless and until the certificates representing their
shares of Common Stock  outstanding  prior to the Reverse Split are surrendered.
Stockholders  should not forward their  certificates to the Exchange Agent until
the letter of transmittal is received and should  surrender  their  certificates
only with such letter of transmittal.

         Payment  in  lieu  of a  fractional  New  Share  will  be  made  to any
stockholder  entitled  thereto  promptly  after  receipt  by the  Company or its
Exchange  Agent  of  a  properly  completed  letter  of  transmittal  and  stock
certificate(s) for all of his or her shares of Common Stock outstanding prior to
the Reverse Split.  There will be no service charge payable by  stockholders  in
connection  with the exchange of  certificates or in connection with the payment

<PAGE>

of cash in lieu of the issuance of a fractional  New Share.  These costs will be
borne by the Company.

Required Vote

         The  affirmative  vote of the  holders of a majority  of the issued and
outstanding  shares of Common Stock entitled to vote on the matter at the Annual
Meeting will be required to approve the Reverse Split described in this Proposal
1.

            The Board of Directors recommends a vote FOR Proposal 1.



                          OTHER BUSINESS OF THE MEETING

         Management  is not aware of any  matters  to come  before  the  Special
Meeting  other than those stated in the Proxy  Statement.  However,  inasmuch as
matters of which  management is not now aware may come before the meeting or any
adjournment thereof, the Proxies confer discretionary  authority with respect to
acting thereon,  and the persons named in such properly  executed Proxies intend
to vote,  act and consent in  accordance  with their best  judgment with respect
thereto. Upon receipt of such Proxies (in the form enclosed) in time for voting,
the shares  represented  thereby will be voted as  indicated  thereon and in the
Proxy Statement.

                                                     HARRY G. McCOY
                                                     Chairman of the Board
                                                     and President


   
St. Paul, Minnesota             
January 19, 1999
    


                              AVAILABLE INFORMATION

The  Company is  subject to the  informational  requirements  of the  Securities
Exchange Act of 1934 (the  "Exchange  Act") and in  accordance  therewith  files
reports, proxy statements and other information with the Securities and Exchange
Commission (the "Commission").  Reports,  proxy statements and other information
filed by the  Company  can be  inspected  and  copied  at the  public  reference
facilities  maintained by the Commission at Judiciary  Plaza,  450 Fifth Street,
N.W.,  Washington,  D.C.  20549 and at its Regional  Offices  located at 75 Park
Place,  New York, New York 10007, and the John C. Kluczynski  Federal  Building,
230 South Dearborn Street, Chicago,  Illinois 60604. Copies of such material can
be obtained  from the Public  Reference  Section of the  Commission at Judiciary
Plaza, 450 Fifth Street, N.W.,  Washington,  D.C. 20549 upon request and payment
of the  prescribed  fees.  The  Commission  maintains  a web site that  contains
reports,  proxy and  information  statements,  and other  information  regarding
issues that are filed electronically with the Commission. The address of the web
site is HTTP://WWW.SEC.GOV.

The  Company's  Common  Stock is  listed on the  American  Stock  Exchange  (the
"AMEX"),  and  reports,  proxy  statements  and other  information  filed by the
Company can be inspected at such exchange.

<PAGE>

                INCORPORATION OF CERTAIN INFORMATION BY REFERENCE

The following documents,  each of which was previously filed by the Company with
the  Commission  pursuant to Section 13 of the Exchange  Act,  are  incorporated
herein by reference:

1. The Company's  Annual Report on Form 10-K for the fiscal year ended  December
   31, 1997.

2. The Company's Report on Form 8-K dated June 3, 1998.

3. The Company's Report on Form 8-K dated September 21, 1998.

All documents  filed by the Company  pursuant to Sections  13(a),  13(c), 14 and
15(d) of the Exchange Act  subsequent  to the date of this Proxy  Statement  and
prior to the  Special  Meeting of  Shareholders  to which  this Proxy  Statement
relates shall be deemed to be incorporated by reference  herein and to be a part
hereof from the date of the filing of such reports and documents.  Any statement
contained in a document  incorporated  or deemed to be incorporated by reference
herein shall be deemed to be modified or  superseded  for purposes of this Proxy
Statement  to the  extent  that a  statement  contained  herein  or in any other
subsequently  filed  document which also is or is deemed to be  incorporated  by
reference herein or in any accompanying Proxy Statement  Supplement  modifies or
supersedes  such statement.  Any such statement so modified or superseded  shall
not be deemed, except as so modified or superseded, to constitute a part of this
Proxy Statement.

         The Company will provide  without charge to each person to whom a Proxy
Statement  is delivered  upon written or oral request of each person,  a copy of
any  documents  incorporated  herein by reference  (other than  exhibits to such
documents unless such exhibits are  specifically  incorporated by reference into
the documents that this Proxy Statement incorporates).  Requests for such copies
should be directed to MEDTOX SCIENTIFIC,  INC., Attention:  Secretary,  402 West
County Road D, St. Paul, Minnesota 55112, (651) 636-7466.



<PAGE>
                                                                   Appendix A




                             MEDTOX SCIENTIFIC, INC.
                         SPECIAL MEETING OF STOCKHOLDERS
                                FEBRUARY 22, 1999

           This Proxy is Solicited on Behalf of the Board of Directors


   
         The undersigned stockholder of MEDTOX Scientific,  Inc. (the "Company")
hereby  appoints Harry G. McCoy and Richard J. Braun,  and each or either one of
them, the true and lawful attorneys, agents, and proxies of the undersigned with
full power of substitution for and in the name of the  undersigned,  to vote all
the shares of Common Stock of MEDTOX SCIENTIFIC,  Inc. which the undersigned may
be entitled to vote at a Special  Meeting of  Stockholders  of the Company to be
held at the  Residence  Inn  located  at 2985  Centre  Point  Drive,  Roseville,
Minnesota on or about Monday,  February 22, 1999, at 9:00 A.M.,  Central Time,
and at any  and  all  adjournments  thereof,  with  all  the  powers  which  the
undersigned would possess if personally present, for the following purposes:
    



                 (Continued and to be signed on the other side)




<PAGE>


         Please mark your
         votes as in this
         example                                   FOR     AGAINST     ABSTAIN
                                                  [   ]    [   ]        [   ]
      For               Withheld
     [   ]               [   ]                1.       To adopt and approve an
                                                       Amendment  to  the
                                                       Company's Certificate of
                                                       Incorporation
                                                       providing   for  a
                                                       one-for-twenty
                                                       reverse stock split  of
                                                       outstanding Common Stock
                                                       of  the Company.

                                              2.       Considering    and
                                                       acting   upon  any
                                                       other      matters
                                                       which may properly
                                                       come   before  the
                                                       meeting   or   any
                                                       adjournment thereof.





[    ]  Please check box if you intend to attend the meeting in person.


This Proxy will be voted for the choices  specified.  If no choice is  specified
with  respect to the  adoption  and  approval to the  Company's  Certificate  of
Incorporation,  this Proxy will be voted FOR the  adoption  and  approval to the
Company's Certificate of Incorporation.
If no choice is specified  for Proposal 2, this Proxy will be voted FOR Proposal
2.

   
The undersigned hereby acknowledges receipt of the Notice of Special Meeting and
Proxy Statement dated January 19, 1999.
    

PLEASE MARK, SIGN, DATE AND MAIL  THIS PROXY IN THE ENVELOPE PROVIDED.

SIGNATURE(S) ________________________________ Dated:___________    _____, 1999
NOTE: Please sign exactly as name appears hereon.  Joint owners should each 
sign. When signing as attorney,  executor,  administrator,  trustee, guardian, 
please give your full title as such.





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