MEDTOX SCIENTIFIC INC
NT 10-K, 1999-03-31
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                                  UNITED STATES

                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                   FORM 12b-25

                           NOTIFICATION OF LATE FILING

                             SEC File Number 1-11394

(Check one):      [X]      Form 10-K and Form 10-KSB
                  [   ]    Form 20-F
                  [ ] Form 11-K [ ] Form 10-Q and Form 10 QSB [ ] Form N-SAR

For Period Ended: December 31, 1998

[ ]  Transition  Report  on Form  10-K [ ]  Transition  Report  on Form 20-F [ ]
Transition Report on Form 11-K [ ] Transition Report on Form 10-Q [ ] Transition
Report on Form N-SAR

For the Transition Period Ended:    N/A

  READ INSTRUCTION (ON BACK PAGE) BEFORE PREPARING FORM. PLEASE PRINT OR TYPE.
              NOTHING IN THIS FORM SHALL BE CONTRUED TO IMPLY THAT
          THE COMMISSION HAS VERIFIED ANY INFORMATION CONTAINED HEREIN.

If the notification relates to a portion of the filing checked above, identify 
the Item(s) to which the notification relates:  N/A

PART I - REGISTRANT INFORMATION

                             MEDTOX SCIENTIFIC, INC.
             (Exact name of registrant as specified in its charter)

                             402 West County Road D
           (Address of Principal Executive Office, Street and Number)

                            St. Paul, Minnesota 55112
                           (City, State and Zip Code)
<PAGE>

PART II - RULES 12b-25 (b) and (c)

If the subject report could not be filed without  unreasonable effort or expense
and the  registrant  seeks relief  pursuant to Rule  12-b-25(b),  the  following
should be completed. (Check box if appropriate)

[X] (a) The  reasons  described  in  reasonable  detail in Part III of this Form
could not be eliminated without unreasonable effort or expense.

[X] (b) The  subject  annual  report on Form 10-K will be filed on or before the
fifteenth calendar day following the prescribed due date; and

[ ] (c) The accountant's  statement or other exhibit required by Rule 12-b-25(c)
has been attached if applicable.

PART III - NARRATIVE

State  below in  reasonable  detail the  reasons  why the Form 10-K could not be
filed within the prescribed time period.

On July 31, 1998, the  Registrant's  Chief  Financial  Officer  resigned and the
position has not been filled to date. The resulting  shortage of financial staff
has  caused a delay in  preparing  the Form 10-K and  completing  the  financial
statements for the year ended December 31, 1998.

PART IV - OTHER INFORMATION

(1)  Name  and  telephone  number  of  person  to  contact  in  regard  to  this
notification:

  Richard J. Braun, Chief Executive Officer          (651)           636-7466
  (Name)                                         (Area Code)  (Telephone Number)

(2) Have all other periodic  reports under Section 13 or 15(d) of the Securities
and  Exchange  Act of 1934 or Section 30 of the  Investment  Company Act of 1940
during the  preceding 12 months or for such shorter  period that the  registrant
was  required  to file such  report(s)  been  filed?  If answer is no,  identify
report(s). [X] Yes [ ] No

(3) Is it anticipated that any significant  change in results of operations from
the  corresponding  period for the last  fiscal  year will be  reflected  by the
earnings statements to be included in the subject report or portion thereof? [ ]
Yes [X] No

         If  so,  attach  an  explanation  of  the  anticipated   change,   both
narratively and  quantitatively,  and, if  appropriate,  state the reasons why a
reasonable estimate of the results cannot be made.

<PAGE>



                             MEDTOX SCIENTIFIC, INC.
                  (Name of Registrant as Specified in Charter)

has caused this notification to be signed on its behalf by the undersigned 
hereunto duly authorized.

Date:    March 30, 1999                     By /s/  Richard J. Braun
                                            Richard J. Braun
                                            Chief Executive Officer

INSTRUCTION: The form may be signed by an executive officer of the registrant or
by any other duly  authorized  representative.  The name and title of the person
signing  the form  shall  be typed or  printed  beneath  the  signature.  If the
statement is signed on behalf of the registrant by an authorized  representative
(other than an executive officer), evidence of the representative's authority to
sign on behalf of the registrant shall be filed with the form.

                                    ATTENTION

Intentional misstatements or omissions of fact constitute federal criminal 
violations (See 18 U.S.C. 1001).





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