INTEGRATED SECURITY SYSTEMS INC
SC 13G, 2000-11-13
COMMUNICATIONS EQUIPMENT, NEC
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                         UNITED STATES
               SECURITIES AND EXCHANGE COMMISSION
                      Washington, DC 20549


                          SCHEDULE 13G

           Under the Securities Exchange Act of 1934

                       (Amendment No.  5)


               Integrated Security Systems, Inc.
_____________________________________________________________________________
                        (Name of Issuer)

                          Common Stock
_____________________________________________________________________________
                 (Title of Class of Securities)

                           45812J101
                   __________________________
                         (CUSIP Number)


<PAGE>
                              13G
CUSIP No.  45812J101
_____________________________________________________________________________
 1. NAME OF REPORTING PERSON           S.S. OR I.R.S. IDENTIFICATION NO.

    Renaissance Capital Growth and Income Fund III, Inc.  75-2533518
_____________________________________________________________________________
 2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
    (a)
    (b)
_____________________________________________________________________________
 3. SEC USE ONLY

_____________________________________________________________________________
 4. CITIZENSHIP OR PLACE OF ORGANIZATION
    Texas
_____________________________________________________________________________

NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH:
_____________________________________________________________________________
 5. SOLE VOTING POWER
    6,374,295 shares
_____________________________________________________________________________
 6. SHARED VOTING POWER
    None
_____________________________________________________________________________
 7. SOLE DISPOSITIVE POWER
    6,374,295 shares
_____________________________________________________________________________
 8. SHARED DISPOSITIVE POWER
    None
_____________________________________________________________________________
 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
    6,374,295 shares
_____________________________________________________________________________
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
    Not applicable
_____________________________________________________________________________
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
    38.51%
_____________________________________________________________________________
12. TYPE OF REPORTING PERSON
    IV
_____________________________________________________________________________
<PAGE>
ITEM 1.
    (a) Name of Issuer.
        Integrated Security Systems, Inc.                         ("Company")

    (b) Address of Issuer's principal Executive Offices
        8200 Springwood Drive, Suite 230
        Irving, TX 75063

ITEM 2.

    (a) Name of Person Filing
        Renaissance Capital Growth and Income Fund III, Inc.      ("Filer")

    (b) Address of principal Business Office or, if none, Residence
        8080 North Central Expwy., Suite 210, LB 59
        Dallas, TX 75206-1857

    (c) Citizenship
        Texas

    (d) Title of Class of Securities
        Common Stock

    (e) CUSIP Number
        75966V105

ITEM 3.  If this statement is filed pursuant to Rule 13d-1(b), or 13d-2(b),
         check whether the person filing is a:

    (a) ______ Broker or Dealer registered under Section 15 of the Act

    (b) ______ Bank as defined in section 3(a)(6) of the Act

    (c) ______ Insurance Company as defined in section 3(a)(19) of the Act

    (d)    X   Investment Company registered under section 8 of the Investment
        ______ Company Act

    (e) ______ Investment Adviser registered under section 203 of the Investment
               Advisers Act of 1940

    (f) ______ Employee Benefit Plan, Pension Fund which is subject to the
               provisions of the Employee Retirement Income Security Act of 1974
               or Endowment Fund; see section 240.13d-1(b)(1)(ii)(F)

    (g) ______ Parent Holding Company, in accordance with section 240.13d-1(b)
               (ii)(G)(Note: See Item 7)

    (h) ______ Group, in accordance with section 240.13d-1(b)(1)(ii)(H)
<PAGE>
ITEM 4.  Ownership.

    (a)  Amount Beneficially Owned:
         At October 1, 1999, Renaissance Capital Growth & Income Fund III, Inc.
         owned a $2,084,101 9% Convertible Debenture due December 1, 2003,
         convertible at $0.549 per share; 393,259 shares of the Company's common
         stock; $375,000 in 9% Convertible Promissory Notes due on demand,
         convertible at $0.549 per share; a warrant to purchase 12,500 shares of
         the Company's common stock on or before November 17, 2002; a warrant to
         purchase 187,500 shares of the Company's common stock on or before
         October 1, 2003;  a warrant to purchase 125,000 shares of the Company's
         common stock on or before October 2, 2003; and a warrant to purchase
         364,299 shares of the Company's common stock.  On October 12, 1999, the
         Fund purchased $150,000 of the Company's Series D Convertible Preferred
         Stock, convertible at $0.80 per share, and a warrant to purchase
         125,000 shares of the Company's common stock.  On October 20, 2000, the
         Filer purchased a $100,000 8% Convertible Promissory Note due and
         payable in 120 days with a conversion price of $0.20 per share.  All
         positions are convertible within sixty days.  Thus, the Filer owns
         6,374,295 shares of the Company's common stock on a fully converted
         basis.  The Investment Advisor is Renaissance Capital Group, Inc.,
         which is also Investment Manager for Renaissance US Growth and Income
         Trust PLC.  Renaissance US Growth and Income Trust PLC also owns
         securities of Integrated Security Systems, Inc.

    (b)  Percent of Class   38.51%

    (c)  Number of shares as to which such person has:

           (i) sole power to vote or to direct the vote:   6,374,295 shares
          (ii) shared power to vote or to direct the vote:   None
         (iii) sole power to dispose or to direct the disposition of:
               6,374,295 shares
          (iv) shared power to dispose or to direct the disposition of:   None

ITEM 5.  Ownership of Five Percent or Less of a Class.

         If this statement is being filed to report the fact that as of the date
         hereof the reporting person has ceased to be the beneficial owner of
         more than five percent of the class of securities, check the following:

ITEM 6.  Ownership of More than Five Percent on Behalf of Another Person.

         Not applicable.

ITEM 7.  Identification and Classification of the Subsidiary Which Acquired the
         Security Being Reported on By the Parent Holding Company.

         Not applicable.

ITEM 8.  Identification and Classification of Members of the Group.

         Not applicable.
<PAGE>
ITEM 9.  Notice of Dissolution of Group.

         Not applicable.

ITEM 10. Certification.

         By signing below I certify that, to the best of my knowledge and
         belief, the securities referred to above were acquired in the ordinary
         course of business and were not acquired for the purpose of and do not
         have the effect of changing or influencing the control of the issuer of
         such securities and were not acquired in connection with or as a
         participant in any transaction having such purposes or effect.

                            SIGNATURE
         After reasonable inquiry and to the best of my knowledge and belief, I
         certify that the information set forth in this statement is true,
         complete and correct.

Date:   November 9, 2000              /S/
                         ____________________________________________________
                                   Signature
                         Russell Cleveland, President and CEO
                         Renaissance Capital Growth and Income Fund III, Inc.
                         ____________________________________________________
                                  Name and Title
<PAGE>


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