MACROCHEM CORP
10-Q, 1997-08-13
PHARMACEUTICAL PREPARATIONS
Previous: PARKER & PARSLEY 83-B LTD, 10-Q, 1997-08-13
Next: FIRST WEST CHESTER CORP, 10-Q, 1997-08-13




                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                    Form 10-Q


(Mark One)
[X]             QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF
                       THE SECURITIES EXCHANGE ACT OF 1934
                  For the quarterly period ended June 30, 1997

                                       or

[ ]            TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF
                       THE SECURITIES EXCHANGE ACT OF 1934
                   For the Transition Period from ____ to ____

                         Commission file number 0-13634

                              MACROCHEM CORPORATION
                          (Exact name of registrant as
                            specified in its charter)


             DELAWARE                                           04-2744744
             --------                                           ----------
   (State or Other Jurisdiction                              (I.R.S. Employer
of Incorporation or Organization)                         Identification Number)

               110 HARTWELL AVENUE, LEXINGTON, MASSACHUSETTS 02173
               ---------------------------------------------------
               (Address of principal executive offices, Zip Code)

                                 (617) 862-4003
                                 --------------
              (Registrant's telephone number, including area code)


     Indicate by check mark whether the Registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of
1934 during the preceding 12 months (or for such shorter period that the
Registrant was required to file such reports) and (2) has been subject to such
filing requirements for the past 90 days.

Yes  X          No
    ---            ---


     As of June 30, 1997, there were 16,150,375 shares of Common Stock, $.01 par
value per share, of the Registrant outstanding.


<PAGE>
                              MACROCHEM CORPORATION

                                      INDEX
                                      -----
   
                                                             PAGE NUMBER
                                                             -----------
PART I   Financial Information

Item 1   Financial Statements (Unaudited)

              Balance Sheets
              June 30, 1997 and December 31, 1996                3-4

              Statements of Operations
              Three Months and Six Months Ended
              June 30, 1997 and 1996                               5

              Statements of Cash Flows
              Six Months Ended  June 30, 1997 and 1996           6-7

              Notes to Financial Statements                      8-9


Item 2   Management's Discussion and Analysis of
         Financial Condition and Results of Operations          9-12


PART II  Other Information

Item 4   Submission of Matters to a Vote of Security Holders      13

Item 6   Exhibits and Reports on Form 8-K                         14


<PAGE>
                         PART I - FINANCIAL INFORMATION

ITEM 1.  UNAUDITED FINANCIAL STATEMENTS
         ------------------------------

                              MACROCHEM CORPORATION
                                 BALANCE SHEETS
                                   (UNAUDITED)

                                     ASSETS

                                              June 30,     December 31,
                                               1997            1996
                                               ----            ----
CURRENT ASSETS:

   Cash and cash equivalents              $  6,772,064    $  7,329,881
   Marketable securities                             -          21,824
   Accounts receivable                          34,850          43,977
   Prepaid expenses and other 
      current assets                           125,886         100,033
                                          ------------    ------------

   TOTAL CURRENT ASSETS                      6,932,800       7,495,715
                                          ------------    ------------

PROPERTY AND EQUIPMENT,
   net of accumulated depreciation: 
      1997-$527,303; 1996-$472,651             306,027         345,343
                                          ------------    ------------

OTHER ASSETS:
      
   Patents, net of accumulated 
      amortization:  1997-$52,457; 
      1996-$46,933                             245,751         218,232
   Deposits                                      4,460           4,460
                                          ------------    ------------

TOTAL ASSETS                              $  7,489,038    $  8,063,750
                                          ============    ============
     
                                                                     (CONTINUED)


<PAGE>


                              MACROCHEM CORPORATION
                                 BALANCE SHEETS
                                    UNAUDITED

                      LIABILITIES AND STOCKHOLDERS' EQUITY
                      ------------------------------------


                                            June 30,              December 31,
                                              1997                    1996
                                              ----                    ----
CURRENT LIABILITIES:
   Current portion of capitalized
      lease obligations                   $     28,669            $     38,630
   Accounts payable and accrued 
      expenses                                 276,219                 281,769
   Accrued compensation                         47,050                  47,050
   Deferred rent                                   ---                   1,014
   Deferred income                              34,850                     ---
                                          ------------            ------------

TOTAL CURRENT LIABILITIES                      386,788                 368,463

CAPITALIZED LEASE OBLIGATIONS,
   net of current portion                        9,483                  18,408
                                          ------------            ------------

TOTAL LIABILITIES                              396,271                 386,871
                                          ------------            ------------
COMMITMENTS AND CONTINGENCIES

STOCKHOLDERS' EQUITY:
   Preferred stock                                ---                      ---
   Common stock, $.01 par value; 
      authorized 60,000,000 shares; 
      issued and outstanding, 
      16,150,375 shares and 15,601,274
      shares at June 30, 1997 and 
      December 31, 1996,
      respectively.                            161,504                 156,013
   Additional paid-in capital               27,246,300              25,839,675
   Unearned compensation                      (402,396)               (222,674)
   Accumulated deficit                     (19,912,641)            (18,096,135)
                                          ------------            ------------
TOTAL STOCKHOLDERS' EQUITY                   7,092,767               7,676,879
                                          ------------            ------------
TOTAL LIABILITIES AND
   STOCKHOLDERS' EQUITY                   $  7,489,038            $  8,063,750
                                          ------------            ------------

The accompanying notes are an integral part of these unaudited financial
statements.
                                                                     (Concluded)
<PAGE>
                              MACROCHEM CORPORATION
                      STATEMENTS OF OPERATIONS (UNAUDITED)
<TABLE>
<CAPTION>

                                   For the three months         For the six months
                                      ended June 30,               ended June 30,
                                   1997          1996           1997          1996
                                   ----          ----           ----          ----
<S>                            <C>           <C>           <C>           <C>
REVENUES:
   
   Research contracts          $       ---   $    82,905   $    50,000   $    82,905
   Product sales                       ---           ---           650           ---
                               -----------   -----------   -----------   -----------

      TOTAL REVENUES                   ---        82,905        50,650        82,905
                               -----------   -----------   -----------   -----------

OPERATING EXPENSES:

   Marketing, general and
      administrative               478,101       846,409       879,908     1,244,678
   Research and development        723,703       505,820     1,168,521       909,709
   Consulting fees with related 
      parties                        3,000         2,000         6,000        12,000
                               -----------   -----------   -----------   -----------
      TOTAL OPERATING
         EXPENSES                1,204,804     1,354,229     2,054,429     2,166,387
                               -----------   -----------   -----------   -----------

   LOSS FROM OPERATIONS         (1,204,804)   (1,271,324)   (2,003,779)   (2,083,482)
                               -----------   -----------   -----------   -----------

OTHER INCOME (EXPENSE):

   Interest income                 102,558       129,184       191,419       196,508
   Interest expense                 (1,943)       (4,811)       (4,145)       (8,372)
   Other                               ---           198           ---            (3)
                               -----------   -----------   -----------   -----------   --------------------
      TOTAL OTHER INCOME           100,615       124,571       187,274       188,133
                               -----------   -----------   -----------   -----------
                         
NET LOSS                       $(1,104,189)  $(1,146,753)  $(1,816,505)  $(1,895,349)
                               ===========   ===========   ===========   ===========

NET LOSS PER SHARE             $     (0.07)  $     (0.07)  $     (0.11)  $     (0.13)
                               ===========   ===========   ===========   ===========

WEIGHTED AVERAGE NUMBER OF
   COMMON SHARES OUTSTANDING    16,049,370    15,476,934    15,892,009    14,939,219
                               ===========   ===========   ===========   ===========
</TABLE>

The accompanying notes are an integral part of these unaudited financial
statements.

<PAGE>
                              MACROCHEM CORPORATION
                      STATEMENTS OF CASH FLOWS (UNAUDITED)

                                               For the six months ended June 30,
                                                  1997                  1996
                                                  ----                  ----

CASH FLOWS FROM OPERATING ACTIVITIES:
   Net Loss                                    $(1,816,505)         $(1,895,349)
                                               -----------          -----------
  Adjustments to reconcile net loss 
      to net cash used by operating
      activities:
         Depreciation and amortization              61,274               50,897
         Stock-based compensation                  113,404              453,884
         Loss on disposal of equipment               1,900                  ---
         Amortization of discounts on
            marketable securities                     (176)             (38,047)

Increase (decrease) in cash from:
   Accounts receivable                               9,127              (41,453)
   Prepaid expenses and other current 
      assets                                       (25,853)             (23,790)
   Accounts payable and accrued expenses            (5,550)               9,190
   Accrued compensation                                ---              (50,000)
   Deferred rent                                    (1,014)              (2,964)
   Deferred income                                  34,850                  --- 
                                               -----------          ----------- 
Total adjustments                                  187,962              357,717
                                               -----------          -----------

Net cash used by operating activities           (1,628,543)          (1,537,632)
                                               -----------          -----------

CASH FLOWS FROM INVESTING ACTIVITIES:        
   Purchases of marketable securities                  ---           (6,478,487)
   Proceeds from maturities of
      marketable securities                         22,000            3,440,000
   Expenditures for property and equipment         (18,335)             (81,232)
   Additions to patents                            (33,042)                 ---
                                               -----------          -----------

   Net cash used for investing activities          (29,377)          (3,119,719)
                                               -----------          -----------
CASH FLOWS FROM FINANCING ACTIVITIES:
   Principal payments on capital leases            (18,886)             (16,938)
   Proceeds from exercise of common 
      stock options                                139,689              396,157
   Proceeds from exercise of common 
      stock warrants                               454,300            2,170,064
   Proceeds from exercise of unit 
      purchase options                             525,000            2,581,250
                                               -----------          -----------
   Net cash provided by financing 
      activities                                 1,100,103            5,130,533
                                               -----------          -----------

The accompanying notes are an integral part of these unaudited financial 
statements.
                                                                     (Continued)
<PAGE>                       

                             MACROCHEM CORPORATION
                      STATEMENTS OF CASH FLOWS (UNAUDITED)
                                                                    (CONTINUED)
                        
                                     For the six months ended June 30,
                                          1997              1996
                                          ----              ----

NET INCREASE (DECREASE) IN CASH
   AND CASH EQUIVALENTS              $  (557,817)       $   473,182

CASH AND CASH EQUIVALENTS,
   BEGINNING OF PERIOD                 7,329,881          3,591,779
                                     -----------        -----------
CASH AND CASH EQUIVALENTS,
   END OF PERIOD                     $ 6,772,064        $ 4,064,961
                                     ===========        ===========


SUPPLEMENTAL DISCLOSURES OF CASH FLOW INFORMATION:

     During the six months ended June 30, 1997 and 1996, cash paid for interest
was $2,815 and $6,892, respectively.

     The Company did not pay any income taxes during those periods.









The accompanying notes are an integral part of these unaudited financial
statements.

                                                                     (Concluded)

<PAGE>


                              MACROCHEM CORPORATION
                     NOTES TO UNAUDITED FINANCIAL STATEMENTS

(1)  As permitted by the rules of the Securities and Exchange Commission (the
     "Commission") applicable to quarterly reports on Form 10-Q, these notes are
     condensed and do not contain all disclosures required by generally accepted
     accounting principles. Reference should be made to the financial statements
     and related notes included in the Company's Annual Report on Form 10-K for
     the year ended December 31, 1996.

     In the opinion of management of the Company, the accompanying unaudited
     financial statements reflect all adjustments which were of a normal
     recurring nature necessary for a fair presentation of the Company's
     financial position, results of operations and cash flows for the three and
     six months ended June 30, 1997 and 1996.

     The results disclosed in the Statements of Operations for the three and six
     months ended June 30, 1997 are not necessarily indicative of the results to
     be expected for the full year.

(2)  Certain prior year amounts have been reclassified to conform to their
     current presentation.

(3)  During 1996, the Company adopted SFAS No. 123, "Accounting for Stock-Based
     Compensation". SFAS No. 123 addresses the financial accounting and
     reporting standards for stock or other equity-based compensation
     arrangements.

     The Company has elected to continue to use the intrinsic value based method
     to account for employee stock option plans and provide disclosures based on
     the fair value method in the notes to the annual financial statements as
     permitted by SFAS No. 123.

     Stock or other equity based compensation for non-employees must be
     accounted for under the fair value based method as required by SFAS No.
     123. Under this method, the equity based instrument is valued at either the
     fair value of the consideration received or equity instrument issued on the
     date of grant. The resulting compensation cost is recognized and charged to
     operations over the service period, which is usually the vesting period.

     During the six months ended June 30, 1997, the Company recorded unearned
     compensation of approximately $293,126 net of a forfeiture of $144,629. The
     unearned compensation will be amortized over the remaining service period
     of the stock-based compensation arrangements. Of the $293,126, $134,918 is
     related to the issuance of 16,000 shares of common stock and $158,208 is
     related to the grant of stock options to consultants.

     For the six months ended June 30, 1997 and 1996, stock-based compensation
     expense of $113,404 and $453,884, respectively, was amortized and charged
     to operations. For the three months ended June 30, 1997 and 1996, stock
     based compensation expense of $72,091 and $453,884, respectively, was
     amortized and charged to operations.

(4)  In March 1997, the Financial Accounting Standards Board released Statement
     of Financial Accounting Standards No. 128, "Earnings Per Share", which is
     effective for fiscal 1997. SFAS No. 128 will require the Company to restate
     amounts previously reported as earnings per share to comply with the
     requirements of SFAS No. 128. The Company has determined that the adoption
     of SFAS No. 128 will have no effect on previously reported earnings per
     share since the results would be anti-dilutive.

(5)  In June 1997, the FASB issued FAS No. 130, "Reporting Comprehensive
     Income," and FAS No. 131, "Disclosures about Segments of an Enterprise and
     Related Information", both of which will be effective for the Company in
     fiscal year 1999. FAS No. 130 establishes standards for the reporting and
     display of comprehensive income and its components (revenues, expenses,
     gains and losses) in a full set of general purpose financial statements.
     FAS No. 131 establishes standards for the way that public business
     enterprises report selected information about operating segments. FAS No.
     131 also establishes standards for related disclosures about products and
     services, geographic areas, and major customers. The implementation of FAS
     No. 130 and FAS No. 131 are not expected to have a material effect on the
     Company's financial statements.

(6)  The Company granted 186,000 common stock options under the 1994 Equity
     Incentive Plan during the six months ended June 30, 1997. During this same
     period, 15,000 options under the 1984 Non-Qualified Stock Option Plan,
     12,000 options under the 1984 Incentive Stock Option Plan and 26,001
     options under the 1994 Equity Incentive Plan were exercised. In addition,
     during this period, 56,000 options under the 1994 Equity Incentive Plan
     were forfeited. All options were granted with an exercise price at the fair
     market value of the underlying common stock determined on the date of
     grant.


ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND
         ---------------------------------------------------------------
         RESULTS OF OPERATIONS.
         ----------------------

GENERAL

     MacroChem Corporation's primary business is the development and
commercialization of transdermal drug delivery compounds and systems designed to
promote the delivery of drugs from the surface of the skin into the skin tissues
and bloodstream. The Company currently derives no significant revenue from
product sales, royalties or license fees. The Company plans to develop specific
SEPA(R) (the Company's proprietary transdermal penetration enhancer)
formulations for use with proprietary and non-proprietary drugs manufactured by
pharmaceutical companies, and to commercialize these products through the
formation of partnerships, strategic alliances and license agreements with those
companies. In order to attract strategic partners, the Company is conducting
clinical testing of certain SEPA-enhanced drugs.

     The Company's results of operations vary significantly from year to year
and quarter to quarter, and depend, among other factors, on the signing of new
licenses and product development agreements, the timing of revenues recognized
pursuant to license agreements, the achievement of milestones by licensees and
the progress of clinical trials conducted by the licensees and the Company. The
timing of the Company's revenues may not match the timing of the Company's
associated product development expenses. To date, research and development
expenses have generally exceeded revenue in any particular period and/or fiscal
year.

RESULTS OF OPERATIONS

THREE MONTHS ENDED JUNE 30, 1997 COMPARED TO THREE MONTHS ENDED JUNE 30, 1996

     During the three months ended June 30, 1997, the Company had no revenues as
compared to revenues of $82,905 during the same period in 1996. The 1996 revenue
was derived from research contracts.

     Marketing, general and administrative expenses decreased significantly
(44%) from the comparable 1996 period, primarily as a result of a $387,000
decrease in stock-based compensation expense compared to the 1996 period.

     Research and development expenses in the 1997 period increased
approximately $218,000 (43%) over the comparable 1996 period due primarily to an
increased effort in the management and execution of the ongoing clinical trials.

     Other income decreased approximately $24,000, resulting primarily from
lower levels of cash and cash equivalents in the 1997 period.
<PAGE>
SIX MONTHS ENDED JUNE 30, 1997 COMPARED TO SIX MONTHS ENDED JUNE 30, 1996

     Total revenues for the six months ended June 30, 1997 were approximately
$51,000 compared to approximately $83,000 for the same period in 1996. This
revenue is primarily due to completed research contracts.

     Marketing, general and administrative expenses decreased approximately
$365,000 (29%) due primarily to a stock-based compensation expense reduction of
approximately $320,000 in 1997 from the comparable 1996 period.

     Research and development costs increased approximately $259,000 (28%) for
the first six months of 1997 compared to the same period in 1996. This increase
was due primarily to an increased effort in the management and execution of the
ongoing clinical trials.

     Other income remained essentially the same for the six month periods ended
June 30, 1997 and 1996. Lower interest income was mostly offset by lower
interest expense on capital leases.

LIQUIDITY AND CAPITAL RESOURCES

     Since inception, the primary source of funding for the Company's operations
has been the private and public sale of its securities, and to a lesser extent,
the licensing of its proprietary technology, government grants and research
contracts.

     The Company's working capital declined approximately $581,000 from December
31, 1996 to June 30, 1997. Working capital used by operations of approximately
$1.6 million was partially offset by proceeds of approximately $1.1 million
received upon the exercise of common stock options, warrants and unit purchase
options.

     Until such time as the Company obtains agreements with third-party
licensees or partners to provide funding for the Company's anticipated business
activities or the Company is able to obtain funds through the private or public
sale of its securities, the Company's working capital will be utilized to fund
its activities.

     Capital expenditures and additional patent development costs for the six
months ended June 30, 1997 aggregated approximately $51,000. The Company expects
additional capital expenditures and patent development costs for the remainder
of the year to aggregate approximately $160,000.

     The Company's long term capital requirements will depend upon numerous
factors including the progress of the Company's research and development
programs; the resources that the Company devotes to clinical testing of SEPA
enhanced compounds, proprietary manufacturing methods and advanced technologies;
the ability of the Company to enter into additional licensing arrangements or
other strategic alliances; the ability of the Company to manufacture products
under those arrangements and the demand for its products or the products of its
licensees or strategic partners if and when approved for sale by regulatory
authorities. In any event, substantial additional funds will be required before
the Company is able to generate revenues sufficient to support its long term
operations. There is no assurance that the Company will be able to obtain such
additional funds on favorable terms, if at all. The Company's inability to raise
sufficient funds could require it to delay, scale back or eliminate certain
research and development programs.

     The Company believes that its existing cash and cash equivalents will be
sufficient to meet its operating expenses and capital expenditure requirements
for at least the next twelve months. The Company's cash requirements may vary
materially from those now planned because of changes in focus and direction of
the Company's research and development programs, competitive and technical
advances, patent developments or other developments. It is not believed that
inflation will have any significant effect on the results of the Company's
operations.
<PAGE>

     THIS REPORT CONTAINS FORWARD-LOOKING STATEMENTS THAT INVOLVE RISKS AND
UNCERTAINTIES. THE COMPANY'S ACTUAL RESULTS MAY DIFFER SIGNIFICANTLY FROM THE
RESULTS DISCUSSED IN THE FORWARD-LOOKING STATEMENTS IN THIS REPORT AND IN
FORWARD-LOOKING STATEMENTS MADE FROM TIME TO TIME BY THE COMPANY ON THE BASIS OF
MANAGEMENT'S THEN-CURRENT EXPECTATIONS. FACTORS THAT MIGHT CAUSE SUCH A
DIFFERENCE INCLUDE, BUT ARE NOT LIMITED TO THE FOLLOWING: THE COMPANY'S HISTORY
OF OPERATING LOSSES AND NEED FOR CONTINUED WORKING CAPITAL; TECHNOLOGICAL
UNCERTAINTY RELATING TO TRANSDERMAL DRUG DELIVERY SYSTEMS AND THE EARLY STAGE OF
DEVELOPMENT OF THE COMPANY'S PROPOSED PRODUCTS; THE COMPANY'S NEED FOR
SIGNIFICANT ADDITIONAL PRODUCT DEVELOPMENT EFFORTS AND ADDITIONAL FINANCING;
UNCERTAINTIES RELATED TO CLINICAL TRIALS OF THE COMPANY'S PROPOSED PRODUCTS; THE
COMPANY'S DEPENDENCE ON THIRD PARTIES FOR DEVELOPMENT AND LICENSING
ARRANGEMENTS; THE LACK OF SUCCESS OF THE COMPANY'S PRIOR DEVELOPMENT EFFORTS;
THE COMPANY'S LACK OF EXPERIENCED MARKETING PERSONNEL AND DEPENDENCE ON THIRD
PARTIES FOR MARKETING AND DISTRIBUTION; THE COMPANY'S DEPENDENCE ON THIRD
PARTIES FOR MANUFACTURING; THE COMPANY'S RELIANCE ON KEY EMPLOYEES, THE LIMITED
PERSONNEL OF THE COMPANY AND ITS DEPENDENCE ON ACCESS TO SCIENTIFIC TALENT;
UNCERTAINTIES RELATING TO COMPETITION, GOVERNMENT REGULATIONS AND PATENT AND
LICENSE RIGHTS; UNCERTAINTIES RELATING TO AVAILABILITY OF ADEQUATE PRODUCT
LIABILITY AND OTHER INSURANCE; UNCERTAINTIES RELATED TO PHARMACEUTICAL PRICING
AND RELATED MATTERS; AND OTHER FACTORS. ADDITIONAL INFORMATION ON THESE AND
OTHER FACTORS WHICH COULD AFFECT THE COMPANY'S ACTUAL RESULTS AND EXPERIENCE ARE
INCLUDED IN THE COMPANY'S ANNUAL REPORT ON FORM 10-K FOR THE YEAR ENDED DECEMBER
31, 1996 AND, IN PARTICULAR, THE SECTION ENTITLED "RISK FACTORS".






<PAGE>


                           PART II - OTHER INFORMATION

ITEM 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS
         ---------------------------------------------------

         On May 23, 1997, the Company held its Annual Meeting of Stockholders to
         vote on the following proposals:

         1.  To elect six members of the Board of Directors.  Nominees for 
             Director were:  a) Carlos M. Samour;  b) Alvin J. Karloff;  
             c) Willard M. Bright; d) Peter G. Martin;  e) Stephen J. Riggi;  
             f) Michael A. Davis  ("Proposal No. 1").

         2.  To ratify the appointment of Deloitte & Touche LLP, as independent 
             auditors for the Company for the fiscal year ending December 31,
             1997.

         3.  To approve an amendment to the Company's 1994 Equity Incentive
             Plan to increase the number of shares of Common Stock that may be
             delivered thereunder from 2,500,000 to 4,000,000.

             Each of the proposals was adopted with a total vote as follows:


                                       Shares
                       Shares       Voting Against         Shares        Broker
Proposal             Voting For  Or Authority Withheld   Abstaining    Non-votes

No. 1

Carlos M. Samour     13,631,568        158,835

Alvin J. Karloff     13,646,818        143,585

Willard M. Bright    13,631,818        158,585

Peter G. Martin      13,654,818        135,585

Stephen J. Riggi     13,654,818        135,585

Michael A. Davis     13,654,818        135,585

No. 2                13,718,618         46,085            25,700

No. 3                 4,529,719      2,167,252           156,050      6,937,382



<PAGE>



ITEM 6.  EXHIBITS AND REPORTS ON FORM 8-K
         --------------------------------

         (a)  The following exhibits are filed herewith:

              10.10.3      1984 Incentive Stock Option Plan as amended
                           November 15, 1996

              11.          Statement of Earnings Per Share

              27.          Financial Data Schedule

              99.1         1994 Equity Incentive Plan as amended May 23, 1997.

         (b)  No reports on Form 8-K were filed during the quarter
              for which this report is filed.


                                   SIGNATURES
                                   ----------


     Pursuant to the requirements of the Securities Exchange Act of 1934, as
amended, the Registrant has duly caused this report to be signed on its behalf
by the undersigned thereunto duly authorized.


                                                     MACROCHEM CORPORATION
                                                     ---------------------
                                                     (Registrant)



August 13, 1997                                      /S/ ALVIN J. KARLOFF
                                                     --------------------
                                                     Alvin J. Karloff
                                                     Chief Executive Officer and
                                                     Principal Financial Officer



                                                    As Amended February 11, 1994
                                                           and November 15, 1996

                              MACROCHEM CORPORATION
                        1984 INCENTIVE STOCK OPTION PLAN

     1. PURPOSE. The purpose of the MacroChem Corporation Incentive Stock Option
Plan (hereinafter referred to as the "Plan") is to provide a special incentive
to selected key employees of MacroChem Corporation (hereinafter referred to as
the "Company") or of any future subsidiary of the Company to improve operations
and to increase profits and to encourage such persons to accept or continue
employment with the Company or any subsidiary of the Company. Accordingly, the
Company will offer to sell shares of common stock of the Company, $0.01 par
value, (the "Stock") as hereinafter provided to such employees of the Company or
of any subsidiary as are designated in accordance with the provisions of the
Plan. For purposes of the Plan, a subsidiary is any corporation in which the
Company owns, directly or indirectly, stock possessing 50% or more of the total
combined voting power of all classes of stock.

     2. ADMINISTRATION. The Plan shall be administered by the Board of Directors
of the Company (the "Board") which shall (a) determine which of the employees of
the Company and its subsidiaries shall be granted options; (b) determine the
time or times when options shall be granted and the number of shares of stock to
be subject to each option; (c) determine the exercise price of the shares
subject to each option and the method of payment of such price; (d) determine
the times or times when each option becomes exercisable and the duration of the
exercise period; (e) prescribe the form or forms of the instruments evidencing
any options granted under the Plan and of any other instruments required under
the Plan and change such forms from time to time; (f) adopt, amend and rescind
rules and regulations for the administration of the Plan; and (g) interpret the
Plan and decide all questions and settle all controversies and disputes which
may arise in connection with the Plan. All decisions, determinations and
interpretations of the Board of Directors shall be binding on all parties
concerned.

     The Board may, in its discretion delegate its powers with respect to the
Plan to a Compensation Committee or any other committee (the "Committee"), in
which event all references to the Board hereunder shall be deemed to refer to
the Committee. The Committee shall consist of at least two directors. A majority
of members of the Committee shall constitute a quorum, and all determinations of
the Committee shall be made by a majority of its members. Any determination of
the Committee under the Plan may be made without notice or meeting of the
Committee by a writing signed by a majority of Committee members. Following
registration of the Common Stock of the Company under the Securities Exchange
Act of 1934, no person shall serve on the Committee unless he is a non-employee
director within the meaning of Rule 16b-3 under that Act.

     3. PARTICIPANTS. The Participants in the Plan shall be key salaried
employees of the Company or of any of its subsidiaries.

     4. LIMITATIONS ON GRANTING OF OPTIONS. The granting of options under the
Plan shall be subject to the following limitations:

                  (a) PERIOD OF GRANT. No option shall be granted under the Plan
         after the expiration of 10 years from the earlier of the date on which
         the Plan is adopted or the date on which it is approved by the
         shareholders of the Company.

                  (b) QUALIFIED PARTICIPANT. Except as hereinafter provided, no
         option shall be granted to a Participant if, at the time of the grant,
         the Participant owns stock possessing more than 10 percent of the total
         combined voting power of all classes of stock of the Company or of its
         subsidiaries. For purposes of determining a Participant's ownership of
         stock for purposes of the preceding sentence, the ownership attribution
         rules of Section 424(d) of the Internal Revenue Code of 1986, as
         amended (the "Code") will apply. The foregoing limitations will not
         apply if (i) the option price is at least 110 percent of the fair
         market value of the stock subject to the option at the time it is
         granted and (ii) the period of the option does not exceed five years
         from the date of grant.

                  (c) MAXIMUM ANNUAL LIMIT. The aggregate fair market value,
         determined at the time the option is granted, of the stock for which
         any Participant may be granted options in any calendar year under the
         Plan (and under all other incentive stock option plans of the Company
         and of its subsidiaries) may not exceed the sum of (i) $100,000 plus
         (ii) any unused limit carryover to such year as determined under the
         applicable provisions of the Code and Treasury Regulations for
         incentive stock options.

         5. TERMS AND CONDITIONS OF OPTIONS. All options granted under the Plan
shall be subject to the following terms and conditions (except as provided in
Sections 7 and 8 below) and to such other terms and conditions consistent with
the applicable provisions of the Internal Revenue Code and Treasury Regulations
for incentive stock options as the Board of Directors shall determine to be
appropriate to accomplish the purposes of the Plan.

                  (a) OPTION PRICE. The option price under each option shall be
         determined by the Board of Directors and shall not be less than 100% of
         the fair market value per share at the time the option is granted; nor
         shall the option price be less, in the case of an original issue of
         authorized stock, than par value. However, if at the time of grant, the
         Participant owns stock possessing more than 10 percent of the total
         combined voting power of all classes of stock of the Company or of its
         subsidiaries, the option price shall not be less than 110% of the fair
         market value of the stock subject to the option.

                  (b) PERIOD OF OPTIONS. An option, by its terms, shall not be
         exercisable after the expiration of 10 years from the date of grant of
         such option. However, if at the time of grant, the Participant owns
         stock possessing more than 10 percent of the total combined voting
         power of all classes of stock of the Company or of its subsidiaries,
         the option, by its terms, shall not be exercisable after the expiration
         of 5 years from the date of grant of such option.

                  (c)  EXERCISE OF OPTIONS.

                           (1) Each option shall be made exercisable at such
                  time or times, whether or not in installments, as the Board of
                  Directors shall prescribe at the time the option is granted.
                  In the case of an option not immediately exercisable in full,
                  the Board of Directors may at any time accelerate the time at
                  which all or any part of the option may be exercised. However,
                  every option, by its terms, shall not be exercisable while
                  there is outstanding (within the meaning of Section 422A(c)(7)
                  of the Internal Revenue Code) any incentive stock option
                  previously granted to the Participant to purchase stock in the
                  Company or in a corporation which (at the time of grant of
                  such option) is a parent or subsidiary of the Company, or is a
                  predecessor corporation of any such corporation.

                           (2) A person electing to exercise an option
                  shall give written notice to the Company, as specified by the
                  Board of Directors, of his election and of the number of
                  shares he has elected to purchase, such notice to be
                  accompanied by:

                                    (i)   the instrument evidencing such option;

                                    (ii)  payment for all shares then being
                           purchased thereunder in full in the form of cash, a
                           certified check or cashier's check or, unless the
                           Board otherwise determines at the time an option is
                           granted, through the delivery of shares of Common
                           Stock (duly owned by the Participant and for which
                           the Participant has good title free and clear of any
                           liens and encumbrances which have been held by the
                           Participant for at least six months (or such shorter
                           period as the Board may determine) having a fair
                           market value on the last business day preceding the
                           date of exercise equal to the purchase price, or a
                           combination of cash and Common Stock or in such other
                           form as the Board shall designate at the time an
                           option is granted;

                                    (iii) payment in cash or by certified or
                           bank check of an amount equal to all applicable
                           local, state or federal withholding taxes, if any, or
                           such other assurance of the payment to the Company of
                           such amount as shall be satisfactory to the Board of
                           Directors in their sole discretion, including if the
                           Board of Directors so determines in the case of an
                           incentive stock option such provision as the Board
                           deems appropriate for the payment of any withholding
                           taxes that may be due upon a later disposition of the
                           stock acquired upon exercise of the option; and

                                    (iv)  any other documents required by the
                           Board of Directors.

                           (3) A person exercising an option shall execute and
                  deliver to the Company any shareholder's agreement or other
                  agreements which the Board of Directors, in its sole
                  discretion, may require at the time of exercise, and unless
                  and until such agreements have been executed and delivered,
                  the Company shall not be obligated to deliver any shares
                  hereunder.

                  (d) DELIVERY OF STOCK. Stock to be delivered under the Plan
         may constitute an original issue of authorized stock or may consist of
         previously issued stock acquired by the Company, as shall be determined
         by the Board. The Board and the proper officers of the Company shall
         take any appropriate action required for such delivery. The Company
         shall not be obligated to deliver any shares unless and until in the
         opinion of the Company's counsel, all applicable federal and state laws
         and regulations have been complied with, nor, in the event the Stock is
         at the time listed upon any stock exchange, unless and until the shares
         to be delivered have been listed or authorized to be added to the list
         upon official notice of issuance upon such exchange, nor unless or
         until all other legal matters in connection with the issuance and
         delivery of shares have been approved by the Company's counsel. Without
         limiting the generality of the foregoing, the Company may require from
         the person exercising an option such investment representation or such
         agreement, if any, as counsel for the Company may consider necessary in
         order to comply with the Securities Act of 1933 and may require that
         the person agree that any sale of the shares will be made only on the
         stock exchange or in such other manner as is permitted by the Board and
         that he will notify the Company when he makes any disposition of the
         shares whether by sale, gift or otherwise. The Company shall use its
         best efforts to effect any such compliance and listing, and the person
         exercising the option shall take any action reasonably requested by the
         Company in such connection. A person exercising an option shall have
         the rights of a shareholder only as to shares actually acquired by him
         under the Plan.

                  (e) NONTRANSFERABILITY OF OPTIONS. Each option, by its terms,
         shall not be transferable by the Participant otherwise than by will or
         by the laws of descent and distribution, and during the Participant's
         lifetime the option shall be exercisable only by him.

                  (f) TERMINATION OF EMPLOYMENT. Except as otherwise provided in
         subparagraphs (g) and (h) below, if the employment of a Participant
         terminates for any reason, his option shall expire immediately and he
         shall not be entitled to purchase any shares.

                  (g) DISABILITY AND RETIREMENT. In the event of termination of
         employment as a result of disability within the meaning of section
         105(d)(4) of the Internal Revenue Code, retirement on or after age 65,
         or retirement on or after age 55 after 10 years of continuous
         employment by the Company, that portion of a Participant's option that
         was exercisable immediately prior to termination will continue to be
         exercisable for the original term of the option, and that portion of
         the option that was not exercisable immediately prior to termination
         will expire, unless otherwise determined by the Board of Directors.

                  (h) DEATH. If a Participant dies at a time when he is entitled
         to exercise an option, then at any time or times within ninety days
         after his death such option may be exercised, as to all or any of the
         shares which the Participant was entitled to purchase immediately prior
         to his death, by his executor or administrator or the person or persons
         to whom the option is transferred by will or the applicable laws of
         descent and distribution, and except as so exercised such option shall
         expire at the end of such period. In no event, however, may any option
         be exercised after the expiration of the option period. If any notice
         of election to exercise an option is given by the executor or
         administrator of a deceased Participant, or by the person or persons to
         whom the option has been transferred by the Participant's will or the
         applicable laws of descent and distribution, the Company shall be under
         no obligation to deliver shares pursuant to such exercise unless and
         until the Company is satisfied that the person or persons giving such
         notice is or are entitled to exercise the option and unless and until
         the persons have executed and delivered any other agreements or
         documents which the Board of Directors may require.

     6. REPLACEMENT OPTIONS. The Company may grant options under the Plan in
substitution for options held by employees of other corporations who
concurrently become employees of the Company or a subsidiary as the result of a
merger or consolidation of another corporation with the Company or subsidiary,
or the acquisition by the Company or a subsidiary of property or stock of
another corporation.

     7. MAXIMUM NUMBER OF SHARES. Subject to adjustment as provided in Section 8
of the Plan, the number of shares of the Stock of the Company which may be
delivered under the Plan shall not exceed 2,000,000 in the aggregate. To the
extent that any options granted under the Plan shall lapse or be terminated, the
shares with respect to which the option has lapsed or been terminated shall
thereafter be available for option under the Plan, within the limit specified
above. The maximum number of shares (subject to adjustment as provided in
Section 8) for which options may be granted to any individual during the term of
the Plan is 160,000 shares. The preceding sentence shall be construed consistent
with the regulations under Section 162(m) of the Code.

     8. CHANGES IN STOCK. In the event of a stock dividend, split-up or
combination of shares, recapitalization or merger in which the Company is the
surviving corporation, or other similar capital change, the number and kind of
shares of stock or securities of the Company to be subject to options then
outstanding, the maximum number of shares or securities which may be issued or
sold under the Plan, the option price and other relevant provisions shall be
appropriately adjusted by the Board of Directors of the Company, whose
determination shall be binding on all persons. In the event of a consolidation
or a merger in which the Company is not the surviving corporation, or which
results in the acquisition of substantially all the Company's outstanding stock
by a single person or entity or by a group of persons and/or entities acting in
concert or in the event of the sale or transfer of substantially all the
Company's assets or a complete liquidation of the Company, all outstanding
options shall thereupon terminate, provided that the Board of Directors may, in
its discretion, make all outstanding options immediately exercisable or arrange
to have any surviving corporation grant replacement options to the Participants.

     9. EMPLOYMENT RIGHTS. The adoption of the Plan does not confer upon any
employee of the Company or a subsidiary any right to continued employment with
the Company or a subsidiary, as the case may be, nor does it interfere in any
way with the right of the Company or a subsidiary to terminate the employment of
any of its employees at any time.

     10. AMENDMENTS. The Board of Directors may at any time discontinue granting
options under the Plan and may at any time amend the Plan or any outstanding
options for the purpose of satisfying the requirements of any changes in
applicable laws or regulations or for any other purpose which may at the time be
permitted by law, provided, however, that (except to the extent required or
permitted under Sections 7 or 8) no amendments shall, without the approval of
the shareholders of the Company (a) increase the maximum number of shares
available under the Plan, (b) change the class of employees eligible for
options, (c) reduce the minimum option price of options thereafter to be granted
below the price provided for in Section 5(a), (d) reduce the option price of
outstanding options, (e) extend the time within which options may be granted,
(f) extend the period of an outstanding option beyond ten years from the date of
grant, (g) alter the restriction on exercising subsequent incentive stock
options which is contained in Section 5(c)(1) or (h) alter the maximum annual
limit of option grants contained in Section 4(c), and no such amendment shall
adversely affect the rights of any Participant (without his consent) under any
option theretofore granted.

     11. EFFECTIVE DATE. The Plan shall become effective as of April 1, 1984,
subject to the approval of the Board of Directors and subject to the vote of the
holders of at least a majority of the shares of the outstanding voting stock of
the Company.


                              MACROCHEM CORPORATION
                   CALCULATION FOR WEIGHTED AVERAGE NUMBER OF
                            COMMON SHARES OUTSTANDING

              WEIGHTED AVERAGE NUMBER OF COMMON SHARES OUTSTANDING
                     FOR THE SIX MONTHS ENDED JUNE 30, 1996

                        CALENDAR DAYS IN THE PERIOD: 182

<TABLE>
<CAPTION>
                                                                            WEIGHTED
                                             COMMON     COMMON               AVERAGE
                                             SHARE      SHARES    DAYS OUT- NUMBER OF
DATE               DESCRIPTION              ACTIVITY  OUTSTANDING STANDING   SHARES
- -------------------------------------------------------------------------------------
<S>                <C>                     <C>        <C>           <C>    <C>
  
DECEMBER 31, 1995  BALANCE                            13,129,321
January 22, 1996   Options Exercised          5,000   13,134,321    161    13,133,744
January 31, 1996   Unit Purchase Options 
                   Exercised                810,000   13,944,321    152    13,810,228
February 1, 1996   Unit Purchase Options 
                   Exercised                210,000   14,154,321    151    13,984,458
February 2, 1996   Unit Purchase Options 
                   Exercised                455,000   14,609,321    150    14,359,458
February 2, 1996   A Warrants Exercised     151,667   14,760,988    150    14,484,459
February 2, 1996   Options Exercised         15,000   14,775,988    150    14,496,821
February 5, 1996   Options Exercised          2,861   14,778,849    147    14,499,132
February 7, 1996   A Warrants Exercised       1,000   14,779,849    145    14,499,929
February 8, 1996   Options Exercised          1,000   14,780,849    144    14,500,149
February 9, 1996   AA Warrants Exercised     81,000   14,861,849    143    14,563,792
February 15, 1996  X Warrants Exercised       3,750   14,865,599    137    14,566,615
February 29, 1996  Options Exercised         30,000   14,895,599    123    14,586,890
February 29, 1996  A Warrants Exercised     200,000   15,095,599    123    14,722,060
February 29, 1996  X Warrants Exercised       1,000   15,096,599    123    14,722,736
March 1, 1996      X Warrants Exercised       1,000   15,097,599    122    14,723,406
March 4, 1996      Options Exercised          2,500   15,100,099    119    14,725,041
March 7, 1996      A Warrants Exercised     140,000   15,240,099    116    14,814,272
March 14, 1996     X Warrants Exercised      10,000   15,250,099    109    14,820,261
March 19, 1996     Options Exercised          5,000   15,255,099    104    14,823,118
March 21, 1996     A Warrants Exercised     100,000   15,355,099    102    14,879,162
April 4, 1996      Options Exercised         31,500   15,386,599     87    14,894,219
April 25, 1996     Options Exercised        120,000   15,506,599     66    14,937,736
May 7, 1996        Options Exercised          5,000   15,511,599     54    14,939,219

JUNE 30, 1996      WEIGHTED AVERAGE NUMBER OF COMMON SHARES OUTSTANDING    14,939,219
                                                   NET LOSS               $(1,895,349)
                                                   NET LOSS PER SHARE     $     (0.13)
                                                                        
</TABLE>
                                                                     (Continued)
<PAGE>
                                                                      Exhibit 11
                                                                     (Continued)
              WEIGHTED AVERAGE NUMBER OF COMMON SHARES OUTSTANDING
                     FOR THE SIX MONTHS ENDED JUNE 30, 1997

                        CALENDAR DAYS IN THE PERIOD: 181
<TABLE>
<CAPTION>
                                                                             WEIGHTED
                                             COMMON     COMMON               AVERAGE
                                             SHARE      SHARES    DAYS OUT-  NUMBER OF
   DATE                DESCRIPTION          ACTIVITY  OUTSTANDING STANDING   SHARES
- -------------------------------------------------------------------------------------
<S>                <C>                       <C>      <C>           <C>    <C>

DECEMBER 31, 1996  BALANCE                            15,601,274
January 14, 1997   A Warrants Exercised         100   15,601,374    168    15,601,367
January 23, 1997   Unit Purchase Options 
                   Exercised                 30,000   15,631,374    159    15,627,720
January 29, 1997   Unit Purchase Options 
                   Exercised                 30,000   15,661,374    153    15,653,080
January 29, 1997   Options Exercised          3,334   15,664,708    153    15,655,898
January 31, 1997   X Warrnts Exercised        1,000   15,665,708    151    15,656,732
February 3, 1997   Options Exercised         13,000   15,678,708    148    15,667,362
February 5, 1997   Options Exercised          2,000   15,680,708    146    15,668,975
February 7, 1997   A Warrants Exercised       1,000   15,681,708    144    15,669,771
February 7, 1997   AA Warrants Exercised      1,000   15,682,708    144    15,670,566
February 7, 1997   Options Exercised          3,000   15,685,708    144    15,672,953
February 10, 1997  Options Exercised          1,000   15,686,708    141    15,673,732
February 10, 1997  X Warrants Exercised      25,000   15,711,708    141    15,693,207
February 14, 1997  A Warrants Exercised      17,000   15,728,708    137    15,706,075
February 18, 1997  Options Exercised          1,500   15,730,208    133    15,707,177
February 19, 1997  Options Exercised         12,000   15,742,208    132    15,715,928
February 24, 1997  Options Exercised            667   15,742,875    127    15,716,396
February 25, 1997  A Warrants Exercised      25,000   15,767,875    126    15,733,799
February 25, 1997  Unit Purchase Options
                   Exercised                 30,000   15,797,875    126    15,754,683
March 4, 1997      Unit Purchase Options
                   Exercised                 30,000   15,827,875    119    15,774,407
March 6, 1997      Options Exercised          1,000   15,828,875    117    15,775,054
March 14, 1997     Options Exercised          5,000   15,833,875    109    15,778,065
March 18, 1997     Unit Purchase Options
                   Exercised                 60,000   15,893,875    105    15,812,871
March 18, 1997     Options Exercised          7,000   15,900,875    105    15,816,932
March 21, 1997     X Warrants Exercised       6,000   15,906,875    102    15,820,313
March 28, 1997     A Warrants Exercised      25,000   15,931,875     95    15,833,435
April 14, 1997     Unit Purchase Options 
                   Exercised                 60,000   15,991,875     77    15,858,960
April 18, 1997     A Warrants Exercised      15,000   16,006,875     73    15,865,009
April 23, 1997     X Warrants Exercised      15,000   16,021,875     68    15,870,645
May 12, 1997       X Warrants Exercised      23,000   16,044,875     50    15,876,998
May 15, 1997       A Warrants Exercised      25,000   16,069,875     47    15,883,490
June 5, 1997       Shares Issued for Service 16,000   16,085,875     26    15,885,788
June 10, 1997      A Warrants Exercised       1,000   16,086,875     21    15,885,904
June 13, 1997      Unit Purchase Options 
                   Exercised                 60,000   16,146,875     18    15,891,871
June 16, 1997      Options Exercised          1,000   16,147,875     15    15,891,954
June 27, 1997      Options Exercised          2,500   16,150,375      4    15,892,009

JUNE 30, 1997      WEIGHTED AVERAGE NUMBER OF COMMON SHARES OUTSTANDING    15,892,009
                                                     NET LOSS             $(1,816,505)
                                                     NET LOSS PER SHARE   $     (0.11)
                                                                                             
</TABLE>
                                                                     (Continued)
<PAGE>
                                                                     EXHIBIT 11 
                                                                     (Continued)

              WEIGHTED AVERAGE NUMBER OF COMMON SHARES OUTSTANDING
                    FOR THE THREE MONTHS ENDED JUNE 30, 1996

                         CALENDAR DAYS IN THE PERIOD: 91
<TABLE>
<CAPTION>

                                                                            WEIGHTED
                                             COMMON     COMMON               AVERAGE
                                             SHARE      SHARES    DAYS OUT- NUMBER OF
   DATE                DESCRIPTION          ACTIVITY  OUTSTANDING STANDING   SHARES                                      OUTSTANDING
- -------------------------------------------------------------------------------------
<S>                <C>                       <C>      <C>            <C>   <C>

MARCH 31, 1996     BALANCE                            15,355,099
april 4, 1996      Options Exercised         31,500   15,386,599     88    15,385,561
April 25, 1996     Options Exercised         20,000   15,506,599     67    15,473,912
May 7, 1996        Options Exercised          5,000   15,511,599     55    15,476,934

JUNE 30, 1996      WEIGHTED AVERAGE NUMBER OF COMMON SHARES OUTSTANDING    15,476,934
                                                     NET LOSS            $ (1,146,753)
                                                     NET LOSS PER SHARE  $      (0.07)
                                                                    
</TABLE>

              WEIGHTED AVERAGE NUMBER OF COMMON SHARES OUTSTANDING
                    FOR THE THREE MONTHS ENDED JUNE 30, 1997

                         CALENDAR DAYS IN THE PERIOD: 91

<TABLE>
<CAPTION>
                                                                            WEIGHTED
                                             COMMON     COMMON               AVERAGE
                                             SHARE      SHARES    DAYS OUT- NUMBER OF
   DATE                DESCRIPTION          ACTIVITY  OUTSTANDING STANDING   SHARES                                      OUTSTANDING
- -------------------------------------------------------------------------------------
<S>                <C>                       <C>      <C>            <C>   <C>

MARCH 31, 1997     BALANCE                            15,931,875
April 14, 1997     Unit Purchase Options 
                   Exercised                 60,000   15,991,875     78    15,983,304
April 18, 1997     A Warrants Exercised      15,000   16,006,875     74    15,995,501
April 23, 1997     X Warrants Exercised      15,000   16,021,875     69    16,006,875
May 12, 1997       X Warrants Exercised      23,000   16,044,875     50    16,019,512
May 15, 1997       A Warrants Exercised      25,000   16,069,875     47    16,032,424
June 5, 1997       Shares Issued for 
                   Services                  16,000   16,085,875     26    16,036,996
June 10, 1997      A Warrants Exercised       1,000   16,086,875     21    16,037,227
June 13, 1997      Unit Purchase Options 
                   Exercised                 60,000   16,146,875     18    16,049,095
June 16, 1997      Options Exercised          1,000   16,147,875     15    16,049,260
June 27, 1997      Options Exercised          2,500   16,150,375      4    16,049,370

JUNE 30, 1997      WEIGHTED AVERAGE NUMBER OF COMMON SHARES OUTSTANDING    16,049,370
                                                     NET LOSS            $ (1,104,189)
                                                     NET LOSS PER SHARE  $      (0.07)
                                                                               
</TABLE>
                                                                     (Concluded)

<TABLE> <S> <C>


<ARTICLE>                     5
<LEGEND>
     This schedule contains summary financial information extracted from the 
Company's balance sheet, statement of operations, statement of stockholder's
equity and statement of cash flows and is qualified in its entirety by reference
to such financial statements.
</LEGEND>
<CIK>                           0000743884                         
<NAME>                          MacroChem Corporation
<MULTIPLIER>                    1
<CURRENCY>                      U.S. Dollars
       
<S>                             <C>
<PERIOD-TYPE>                   6-MOS
<FISCAL-YEAR-END>               DEC-31-1997
<PERIOD-START>                  JAN-1-1997
<PERIOD-END>                    JUN-30-1997
<EXCHANGE-RATE>                 1
<CASH>                          $6,772,064
<SECURITIES>                    0
<RECEIVABLES>                   34,850
<ALLOWANCES>                    0
<INVENTORY>                     0
<CURRENT-ASSETS>                6,932,800
<PP&E>                          833,330
<DEPRECIATION>                  527,303
<TOTAL-ASSETS>                  7,489,038
<CURRENT-LIABILITIES>           386,788
<BONDS>                         9,483
           0
                     0
<COMMON>                        161,504
<OTHER-SE>                      6,931,263
<TOTAL-LIABILITY-AND-EQUITY>    7,489,038
<SALES>                         650
<TOTAL-REVENUES>                50,650
<CGS>                           0               
<TOTAL-COSTS>                   0               
<OTHER-EXPENSES>                0               
<LOSS-PROVISION>                0               
<INTEREST-EXPENSE>              4,145               
<INCOME-PRETAX>                 (1,816,505)               
<INCOME-TAX>                    0               
<INCOME-CONTINUING>             0               
<DISCONTINUED>                  0               
<EXTRAORDINARY>                 0               
<CHANGES>                       0               
<NET-INCOME>                    $(1,816,505)               
<EPS-PRIMARY>                   $(.11)               
<EPS-DILUTED>                   $(.11)               
        


</TABLE>


                                                    As amended November 15, 1996
                                                                and May 23, 1997


                              MACROCHEM CORPORATION
                           1994 EQUITY INCENTIVE PLAN


1.   PURPOSE

     The purpose of this 1994 Equity Incentive Plan (the "Plan") is to advance
the interests of MacroChem Corporation (the "Company") by enhancing its ability
to attract and retain employees and other persons or entities who are in a
position to make significant contributions to the success of the Company and its
subsidiaries through ownership of shares of the Company's common stock
("Stock").

     The Plan is intended to accomplish these goals by enabling the Company to
grant Awards in the form of Options, Stock Appreciation Rights, Restricted Stock
or Unrestricted Stock Awards, Deferred Stock Awards, Performance Awards, Loans
or Supplement Grants, or combinations thereof, all as more fully described
below.


2.   ADMINISTRATION

     Unless otherwise determined by the Board of Directors of the Company (the
"Board"), the Plan will be administered by a Committee of the Board designated
for such purpose (the "Committee"). The Committee shall consist of at least two
directors. A majority of the members of the Committee shall constitute a quorum,
and all determinations of the Committee shall be made by a majority of its
members. Any determination of the Committee under the Plan may be made without
notice or meeting of the Committee by a writing signed by a majority of the
Committee members. So long as the Stock is registered under the Securities
Exchange Act of 1934 (the "1934 Act"), all members of the Committee shall be
non-employee directors within the meaning of Rule 16b-3 under the 1934 Act. The
Committee will have authority, not inconsistent with the express provisions of
the Plan and in addition to other authority granted under the Plan, to (a) grant
Awards at such time or times as it may choose; (b) determine the size of each
Award, including the number of shares of Stock subject to the Award; (c)
determine the type or types of each Award; (d) determine the terms and
conditions of each Award; (e) waive compliance by a Participant (as defined
below) with any obligations to be performed by the Participant under an Award
and waive any term or condition of an Award; (f) amend or cancel an existing
Award in whole or in part (and if an award is canceled, grant another Award in
its place on such terms as the Committee shall specify), except that the
Committee may not, without the consent of the holder of an Award, take any
action under this clause with respect to such Award if such action would
adversely affect the rights of such holder; (g) prescribe the form or forms of
instruments that are required or deemed appropriate under the Plan, including
any written notices and elections required of Participants, and change such
forms from time to time; (h) adopt, amend and rescind rules and regulations for
the administration of the Plan; and (i) interpret the Plan and decide any
questions and settle all controversies and disputes that may arise in connection
with the Plan. Such determinations and actions of the Committee, and all other
determinations and actions of the Committee made or taken under authority
granted by any provision of the Plan, will be conclusive and will bind all
parties. Nothing in this paragraph shall be construed as limiting the power of
the Committee to make adjustments under Section 7.3 or Section 8.6.

     With respect to persons subject to Section 16 of the 1934 Act, transactions
under this plan are intended to comply with all applicable conditions of Rule
16b-3 or its successors under the 1934 Act. To the extent any action by the
Committee or Board fails to so comply, it shall be deemed null and void, to the
extent permitted by law and deemed advisable by the Committee.


3.   EFFECTIVE DATE AND TERM OF PLAN

     The Plan will become effective on the date on which it is approved by the
stockholders of the Company. Grants of Awards under the Plan may be made prior
to that date, subject to such approval of the Plan. No Award may be granted
under the Plan after February 11, 2004, but Awards previously granted may extend
beyond that date.


4.   SHARES SUBJECT TO THE PLAN

     Subject to the adjustment as provided in Section 8.6 below, the aggregate
number of shares of Stock that may be delivered under the Plan will be
4,000,000. If any Award requiring exercise for delivery of Stock terminates
without having been exercised in full, or if any Award payable in Stock or cash
is satisfied in cash rather than Stock, the number of shares of Stock as to
which such Award was not exercised or for which cash was substituted will be
available for future grants. The maximum number of shares (subject to adjustment
as provided in Section 8.6 below) with respect to which Awards may be made to
any one Participant during the term of the Plan shall be 750,000 shares. The
preceding sentence shall be construed consistent with the regulations under
Section 162(m) of the Internal Revenue Code of 1986, as amended (the "Code").

     Stock delivered under the Plan may be either authorized but unissued Stock
or previously issued Stock acquired by the Company and held in treasury. No
fractional shares of Stock will be delivered under the Plan.


5.   ELIGIBILITY AND PARTICIPATION

     Those eligible to receive Awards under the Plan ("Participants") will be
persons in the employ of the Company or any of its subsidiaries ("Employees")
and other persons or entities (including without limitation non-Employee
directors of the Company or a subsidiary of the Company) who, in the opinion of
the Committee, are in a position to make a significant contribution to the
success of the Company or its subsidiaries. A "subsidiary" for purposes of the
Plan will be a corporation in which the Company owns, directly or indirectly,
stock possessing 50% or more of the total combined voting power of all classes
of stock.


6.   TYPES OF AWARDS

          6.1.     OPTIONS

         (a) NATURE OF OPTIONS. An Option is an Award entitling the holder on
exercise thereof to purchase Stock at a specified exercise price.

         Both "incentive stock options," as defined in Section 422 of the Code
(any Option intended to qualify as an incentive stock option being hereinafter
referred to as an "ISO"), and Options that are not incentive stock options, may
be granted under the Plan. ISOs shall be awarded only to Employees.

         (b) EXERCISE PRICE.  The exercise price of an Option will be determined
by the Board subject to the following:

              (1) The exercise price of an ISO shall not be less than 100% (110%
         in the case of an ISO granted to a ten-percent stockholder) of the fair
         market value of the Stock subject to the Option, determined as of the
         time the Option is granted. A "ten-percent stockholder" is any person
         who at the time of grant owns, directly or indirectly, or is deemed to
         own by reason of the attribution rules of section 424(d) of the Code,
         stock possessing more than 10% of the total combined voting power of
         all classes of stock of the Company or of any of its subsidiaries.
<PAGE>
              (2) In no case may the exercise price paid for Stock which is part
         of an original issue of authorized Stock be less than the par value per
         share of the Stock.

              (3) The Committee may reduce the exercise price of an Option at
         any time after the time of grant, but in the case of an Option
         originally awarded as an ISO, only with the consent of the Participant.

         (c) DURATION OF OPTIONS. The latest date on which an Option may be
exercised will be the tenth anniversary (fifth anniversary, in the case of an
ISO granted to a ten-percent stockholder) of the day immediately preceding the
date the Option was granted, or such earlier date as may have been specified by
the Committee at the time the Option was granted.

         (d) EXERCISE OF OPTIONS. Options granted under any single Award will
become exercisable at such time or times, and on such conditions, as the
Committee may specify. The Committee may at any time and from time to time
accelerate the time at which all or any part of the Option may be exercised.

         Any exercise of an Option must be in writing, signed by the proper
person and delivered or mailed to the Company, accompanied by (1) any documents
required by the Committee and (2) payment in full in accordance with paragraph
(e) below for the number of shares for which the Option is exercised.

         (e) PAYMENT FOR STOCK. Stock purchased on exercise of an Option must be
paid for as follows: (1) in cash or by check (acceptable to the Company in
accordance with guidelines established for this purpose), bank draft or money
order payable to the order of the Company or (2) if so permitted by the
instrument evidencing the Option (or in the case of an Option which is not an
ISO, by the Committee at or after grant of the Option), (i) through the delivery
of shares of Stock which have been outstanding for at least six months (unless
the Committee expressly approves a shorter period) and which have a fair market
value on the last business day preceding the date of exercise equal to the
exercise price, or (ii) by delivery of a promissory note of the Option holder to
the Company, payable on such terms as are specified by the Committee, or (iii)
by delivery of an unconditional and irrevocable undertaking by a broker to
deliver promptly to the Company sufficient funds to pay the exercise price, or
(iv) by any combination of the permissible forms of payment; PROVIDED, that if
the Stock delivered upon exercise of the Option is an original issue of
authorized Stock, at least so much of the exercise price as represents the par
value of such Stock must be paid other than by the Option holder's promissory
note.

         (f) DISCRETIONARY PAYMENTS. If the market price of shares of Stock
subject to an Option (other than an Option which is in tandem with a Stock
Appreciation Right as described in Section 6.2 below) exceeds the exercise price
of the Option at the time of its exercise, the Committee may cancel the Option
and cause the Company to pay in cash or in shares of Common Stock (at a price
per share equal to the fair market value per share) to the person exercising the
Option an amount equal to the difference between the fair market value of the
Stock which would have been purchased pursuant to the exercise (determined on
the date the Option is canceled) and the aggregate exercise price which would
have been paid. The Committee may exercise its discretion to take such action
only if it has received a written request from the person exercising the Option,
but such a request will not be binding on the Committee.

         6.2.     STOCK APPRECIATION RIGHTS.

         (a) NATURE OF STOCK APPRECIATION RIGHTS. A Stock Appreciation Right is
an Award entitling the recipient on exercise of the Right to receive an amount,
in cash or Stock or a combination thereof (such form to be determined by the
Committee), determined in whole or in part by reference to appreciation in Stock
value.

         In general, a Stock Appreciation Right entitles the Participant to
receive, with respect to each share of Stock as to which the Right is exercised,
the excess of the share's fair market value on the date of exercise over its
fair market value on the date the Right was granted. However, the Committee may
provide at the time of grant that the amount the recipient is entitled to
receive will be adjusted upward or downward under rules established by the
Committee to take into account the performance of the Stock in comparison with
the performance of other stocks or an index or indices of other stocks. The
Committee may also grant Stock Appreciation Rights providing that following a
change in control of the Company, as determined by the Committee, the holder of
such Right will be entitled to receive, with respect to each share of Stock
subject to the Right, an amount equal to the excess of a specified value (which
may include an average of values) for a share of Stock during a period preceding
such change in control over the fair market value of a share of Stock on the
date the Right was granted.

         (b) GRANT OF STOCK APPRECIATION RIGHTS. Stock Appreciation Rights may
be granted in tandem with, or independently of, Options granted under the Plan.
A Stock Appreciation Right granted in tandem with an Option which is not an ISO
may be granted either at or after the time the Option is granted. A Stock
Appreciation Right granted in tandem with an ISO may be granted only at the time
the Option is granted.

         (c)  RULES APPLICABLE TO TANDEM AWARDS.  When Stock Appreciation Rights
are granted in tandem with Options, the following will apply:

              (1) The Stock Appreciation Right will be exercisable only at such
         time or times, and to the extent, that the related Option is
         exercisable and will be exercisable in accordance with the procedure
         required for exercise of the related Option.

              (2) The Stock Appreciation Right will terminate and no longer be
         exercisable upon the termination or exercise of the related Option,
         except that a Stock Appreciation Right granted with respect to less
         than the full number of shares covered by an Option will not be reduced
         until the number of shares as to which the related Option has been
         exercised or has terminated exceeds the number of shares not covered by
         the Stock Appreciation Right.

              (3) The Option will terminate and no longer be exercisable upon
         the exercise of the related Stock Appreciation Right.

              (4) The Stock Appreciation Right will be transferable only with
         the related Option.

              (5) A Stock Appreciation Right granted in tandem with an ISO may
         be exercised only when the market price of the Stock subject to the
         Option exceeds the exercise price of such option.

         (d) EXERCISE OF INDEPENDENT STOCK APPRECIATION RIGHTS. A Stock
Appreciation Right not granted in tandem with an Option will become exercisable
at such time or times, and on such conditions, as the Committee may specify. The
Committee may at any time accelerate the time at which all or any part of the
Right may be exercised.

         Any exercise of an independent Stock Appreciation Right must be in
writing, signed by the proper person and delivered or mailed to the Company,
accompanied by any other documents required by the Committee.

         6.3.     RESTRICTED AND UNRESTRICTED STOCK.

         (a) NATURE OF RESTRICTED STOCK AWARD. A Restricted Stock Award entitles
the recipient to acquire, for a purchase price equal to par value, shares of
Stock subject to the restrictions described in paragraph (d) below ("Restricted
Stock").

         (b) ACCEPTANCE OF AWARD. A Participant who is granted a Restricted
Stock Award will have no rights with respect to such Award unless the
Participant accepts the Award by written instrument delivered or mailed to the
Company accompanied by payment in full of the specified purchase price, if any,
of the shares covered by the Award. Payment may be by certified or bank check or
other instrument acceptable to the Committee.

          (c) RIGHTS AS A STOCKHOLDER. A Participant who receives Restricted
Stock will have all the rights of a stockholder with respect to the Stock,
including voting and dividend rights, subject to the restrictions described in
paragraph (d) below and any other conditions imposed by the Committee at the
time of grant. Unless the Committee otherwise determines, certificates
evidencing shares of Restricted Stock will remain in the possession of the
Company until such shares are free of all restrictions under the Plan.

         (d) RESTRICTIONS. Except as otherwise specifically provided by the
Plan, Restricted Stock may not be sold, assigned, transferred, pledged or
otherwise encumbered or disposed of, and if the Participant ceases to be an
Employee or otherwise suffers a Status Change (as defined at Section 7.2(a)
below) for any reason, must be offered to the Company for purchase for the
amount of cash paid for the Stock, or forfeited to the Company if no cash was
paid. These restrictions will lapse at such time or times, and on such
conditions, as the Committee may specify. The Committee may at any time
accelerate the time at which the restrictions on all or any part of the shares
will lapse.

         (e) NOTICE OF ELECTION. Any Participant making an election under
Section 83(b) of the Code with respect to Restricted Stock must provide a copy
thereof to the Company within 10 days of the filing of such election with the
Internal Revenue Service.

         (f) OTHER AWARDS SETTLED WITH RESTRICTED STOCK. The Committee may, at
the time any Award described in this Section 6 is granted, provide that any or
all the Stock delivered pursuant to the Award will be Restricted Stock.

         (g) UNRESTRICTED STOCK. The Committee may, in its sole discretion,
approve the sale to any Participant of shares of Stock free of restrictions
under the Plan for a price which is not less than the par value of the Stock.

         6.4.  DEFERRED STOCK.

         A Deferred Stock Award entitles the recipient to receive shares of
Stock to be delivered in the future. Delivery of the Stock will take place at
such time or times, and on such conditions, as the Committee may specify. The
Committee may at any time accelerate the time at which delivery of all or any
part of the Stock will take place. At the time any Award described in this
Section 6 is granted, the Committee may provide that, at the time Stock would
otherwise be delivered pursuant to the Award, the Participant will instead
receive an instrument evidencing the Participant's right to future delivery of
Deferred Stock.

         6.5.  PERFORMANCE AWARDS; PERFORMANCE GOALS.

         (a) NATURE OF PERFORMANCE AWARDS. A Performance Award entitles the
recipient to receive, without payment, an amount in cash or Stock or a
combination thereof (such form to be determined by the Committee) following the
attainment of Performance Goals. Performance Goals may be related to personal
performance, corporate performance, departmental performance or any other
category of performance deemed by the Committee to be important to the success
of the Company. The Committee will determine the Performance Goals, the period
or periods during which performance is to be measured and all other terms and
conditions applicable to the Award.

         (b) OTHER AWARDS SUBJECT TO PERFORMANCE CONDITION. The Committee may,
at the time any Award described in this Section 6 is granted, impose the
condition (in addition to any conditions specified or authorized in this Section
6 or any other provision of the Plan) that Performance Goals be met prior to the
Participant's realization of any payment or benefit under the Award.

         6.6.  LOANS AND SUPPLEMENTAL GRANTS.

         (a) LOANS. The Company may make a loan to a Participant ("Loan"),
either on the date of or after the grant of any Award to the Participant. A Loan
may be made either in connection with the purchase of Stock under the Award or
with the payment of any Federal, state and local income tax with respect to
income recognized as a result of the Award. The Committee will have full
authority to decide whether to make a Loan and to determine the amount, terms
and conditions of the Loan, including the interest rate (which may be zero),
whether the Loan is to be secured or unsecured or with or without recourse
against the borrower, the terms on which the Loan is to be repaid and the
conditions, if any, under which it may be forgiven. However, no Loan may have a
term (including extensions) exceeding ten years in duration.

         (b) SUPPLEMENTAL GRANTS. In connection with any Award, the Committee
may at the time such Award is made or at a later date, provide for and grant a
cash award to the Participant ("Supplemental Grant") not to exceed an amount
equal to (1) the amount of any federal, state and local income tax on ordinary
income for which the Participant may be liable with respect to the Award,
determined by assuming taxation at the highest marginal rate, plus (2) an
additional amount on a grossed-up basis intended to make the Participant whole
on an after-tax basis after discharging all the Participant's income tax
liabilities arising from all payments under this Section 6. Any payments under
this subsection (b) will be made at the time the Participant incurs Federal
income tax liability with respect to the Award.

7.   EVENTS AFFECTING OUTSTANDING AWARDS

         7.1.  DEATH.

         If a Participant dies, the following will apply:

         (a) All Options and Stock Appreciation Rights held by the Participant
immediately prior to death, to the extent then exercisable, may be exercised by
the Participant's executor or administrator or the person or persons to whom the
Option or Right is transferred by will or the applicable laws of descent and
distribution, and all Options originally issued to the Participant and
transferred pursuant to Section 8.5 hereof may be exercised by the person or
persons to whom the Option has been so transferred, at any time within the one
year period ending with the first anniversary of the Participant's death (or
such shorter or longer period as the Committee may determine), and shall
thereupon terminate. In no event, however, shall an Option or Stock Appreciation
Right remain exercisable beyond the latest date on which it could have been
exercised without regard to this Section 7. Except as otherwise determined by
the Committee, all Options originally issued to a Participant and all Stock
Appreciation Rights held by a Participant immediately prior to death that are
not then exercisable shall terminate at death.

         (b) Except as otherwise determined by the Committee, all Restricted
Stock held by the Participant must be transferred to the Company (and, in the
event the certificates representing such Restricted Stock are held by the
Company, such Restricted Stock will be so transferred without any further action
by the Participant) in accordance with Section 6.3 above.

         (c) Any payment or benefit under a Deferred Stock Award, Performance
Award, or Supplemental Grant to which the Participant was not irrevocably
entitled prior to death will be forfeited and the Award canceled, as of the time
of death, unless otherwise determined by the Committee.

         7.2.  TERMINATION OF SERVICE (OTHER THAN BY DEATH).

         If a Participant who is an Employee ceases to be an Employee for any
reason other than death, or if there is a termination (other than by reason of
death) of the consulting, service or similar relationship in respect of which a
non-Employee Participant was granted an Award hereunder (such termination of the
employment or other relationship being hereinafter referred to as a "Status
Change"), the following will apply:

         (a) Except as otherwise determined by the Committee, all Options and
Stock Appreciation Rights originally issued to the Participant that were not
exercisable immediately prior to the Status Change shall terminate at the time
of the Status Change. Any Options or Rights that were exercisable immediately
prior to the Status Change will continue to be exercisable for a period of six
months (or such longer period as the Committee may determine), and shall
thereupon terminate, unless (i) the Award provides by its terms for immediate
termination in the event of a Status Change, (ii) the Status Change results from
(w) retirement of the Participant on or after age 65, (x) retirement on or after
age 55 after 10 years of continuous employment by the Company, (y) disability
(as determined by the Company), or (z) termination of the Participant's service
as a director if the Participant is a non-Employee director, in which cases that
portion of the Options originally issued to the Participant that was exercisable
immediately prior to the Status Change will continue to be exercisable for the
original term of the Option or (iii) unless the Status Change results from a
discharge for cause which in the opinion of the Committee casts such discredit
on the Participant as to justify immediate termination of the Award. In no
event, however, shall an Option or Stock Appreciation Right remain exercisable
beyond the latest date on which it could have been exercised without regard to
this Section 7. For purposes of this paragraph, in the case of a Participant who
is an Employee, a Status Change shall not be deemed to have resulted by reason
of (i) a sick leave or other bona fide leave of absence approved for purposes of
the Plan by the Committee, so long as the Employee's right to reemployment is
guaranteed either by statute or by contract, or (ii) a transfer of employment
between the Company and a subsidiary or between subsidiaries, or to the
employment of a corporation (or a parent or subsidiary corporation of such
corporation) issuing or assuming an option in a transaction to which section
424(a) of the Code applies.

         (b) Except as otherwise determined by the Committee, all Restricted
Stock held by the Participant at the time of the Status Change must be
transferred to the Company (and, in the event the certificates representing such
Restricted Stock are held by the Company, such Restricted Stock will be so
transferred without any further action by the Participant) in accordance with
Section 6.3 above.

         (c) Any payment or benefit under a Deferred Stock Award, Performance
Award, or Supplemental Grant to which the Participant was not irrevocably
entitled prior to the Status Change will be forfeited and the Award canceled as
of the date of such Status Change unless otherwise determined by the Committee.

         7.3.  CERTAIN CORPORATE TRANSACTIONS.

                  7.3.1.  MERGERS, SALES ETC.

         In the event of a consolidation or merger in which the Company is not
the surviving corporation or which results in the acquisition of substantially
all the Company's outstanding Stock by a single person or entity or by a group
of persons and/or entities acting in concert, or in the event of the sale or
transfer of substantially all the Company's assets or a dissolution or
liquidation of the Company (a "covered transaction"), all outstanding Awards
will terminate as of the effective date of the covered transaction, and the
following rules shall apply:

         (a) Subject to paragraphs (b) and (c) below, the Committee shall, at
least twenty (20) days prior to the effective date of the covered transaction,
(1) make each outstanding Option and Stock Appreciation Right exercisable in
full, (2) remove the restrictions from each outstanding share of Restricted
Stock, (3) cause the Company to make any payment and provide any benefit under
each outstanding Deferred Stock Award, Performance Award, and Supplemental Grant
which would have been made or provided with the passage of time had the
transaction not occurred and the Participant not suffered a Status Change (or
died), and (4) forgive all or any portion of the principal of or interest on a
Loan.

         (b) If an outstanding Award is subject to performance or other
conditions (other than conditions relating only to the passage of time and
continued employment) which will not have been satisfied at the time of the
covered transaction, the Committee may in its sole discretion remove such
conditions. If it does not do so, however, such Award will terminate as of the
date of the covered transaction notwithstanding paragraph (a) above.

         (c) With respect to an outstanding Award held by a participant who,
following the covered transaction, will be employed by or otherwise providing
services to a corporation which is a surviving or acquiring corporation in such
transaction or an affiliate of such a corporation, the Committee may, in lieu of
the action described in paragraph (a) above, arrange to have such surviving or
acquiring corporation or affiliate grant to the Participant a replacement award
which, in the judgment of the Committee, is substantially equivalent to the
Award.
                  7.3.2.  LIQUIDATION AND DISSOLUTION.

         In the event of a dissolution or liquidation of the Company, all
outstanding Awards will terminate as of the effective date of such dissolution
or liquidation, and the following rules shall apply:

         (a) Subject to paragraphs (b) and (c) below, the Committee may, prior
to the effective date of such liquidation or dissolution, (1) make each
outstanding Option and Stock Appreciation Right exercisable in full, (2) remove
the restrictions from each outstanding share of Restricted Stock, (3) cause the
Company to make any payment and provide any benefit under each outstanding
Deferred Stock Award, Performance Award, and Supplemental Grant which would have
been made or provided with the passage of time had the transaction not occurred
and the Participant not suffered a Status Change (or died), and (4) forgive all
or any portion of the principal of or interest on a Loan.

         (b) If an outstanding Award is subject to performance or other
conditions (other than conditions relating only to the passage of time and
continued employment) which will not have been satisfied at the time of such
liquidation or dissolution, the Committee may in its sole discretion remove such
conditions. If it does not do so, however, such Award will terminate as of the
date of such liquidation or dissolution notwithstanding paragraph (a) above.

         (c) With respect to an outstanding Award held by a participant who,
following such liquidation or dissolution, will be employed by or otherwise
providing services to a corporation which is a surviving or acquiring
corporation in such transaction or an affiliate of such a corporation, the
Committee may, in lieu of the action described in paragraph (a) above, arrange
to have such surviving or acquiring corporation or affiliate grant to the
Participant a replacement award which, in the judgment of the Committee, is
substantially equivalent to the Award.

8.   GENERAL PROVISIONS

         8.1.  DOCUMENTATION OF AWARDS.

         Awards will be evidenced by such written instruments, if any, as may be
prescribed by the Committee from time to time. Such instruments may be in the
form of agreements to be executed by both the Participant and the Company, or
certificates, letters or similar instruments, which need not be executed by the
Participant but acceptance of which will evidence agreement to the terms
thereof.

         8.2.  RIGHTS AS A STOCKHOLDER, DIVIDEND EQUIVALENTS.

         Except as specifically provided by the Plan, the receipt of an Award
will not give a holder rights as a stockholder; the holder will obtain such
rights, subject to any limitations imposed by the Plan or the instrument
evidencing the Award, upon actual receipt of Stock. However, the Committee may,
on such conditions as it deems appropriate, provide that a holder will receive a
benefit in lieu of cash dividends that would have been payable on any or all
Stock subject to the holder's Award had such Stock been outstanding. Without
limitation, the Committee may provide for payment to the holder of amounts
representing such dividends, either currently or in the future, or for the
investment of such amounts on behalf of the holder.

         8.3.  CONDITIONS ON DELIVERY OF STOCK.

         The Company will not be obligated to deliver any shares of Stock
pursuant to the Plan or to remove restrictions from shares previously delivered
under the Plan (a) until all conditions of the Award have been satisfied or
removed, (b) until, in the opinion of the Company's counsel, all applicable
federal and state laws and regulations have been complied with, (c) if the
outstanding Stock is at the time listed on any stock exchange, until the shares
to be delivered have been listed or authorized to be listed on such exchange
upon official notice of notice of issuance, and (d) until all other legal
matters in connection with the issuance and delivery of such shares have been
approved by the Company's counsel. If the sale of Stock has not been registered
under the Securities Act of 1933, as amended, the Company may require, as a
condition to exercise of the Award, such representations or agreements as
counsel for the Company may consider appropriate to avoid violation of such Act
and may require that the certificates evidencing such Stock bear an appropriate
legend restricting transfer.

         If an Award is exercised by the Participant's legal representative, the
Company will be under no obligation to deliver Stock pursuant to such exercise
until the Company is satisfied as to the authority of such representative.

         8.4.  TAX WITHHOLDING.

         The Company will withhold from any cash payment made pursuant to an
Award an amount sufficient to satisfy all federal, state and local withholding
tax requirements (the "withholding requirements").

         In the case of an Award pursuant to which Stock may be delivered, the
Committee will have the right to require that the Participant or other
appropriate person remit to the Company an amount sufficient to satisfy the
withholding requirements, or make other arrangements satisfactory to the
Committee with regard to such requirements, prior to the delivery of any Stock.
If and to the extent that such withholding is required, the Committee may permit
the Participant or such other person to elect at such time and in such manner as
the Committee provides to have the Company hold back from the shares to be
delivered, or to deliver to the Company, Stock having a value calculated to
satisfy the withholding requirement. The Committee may make such share
withholding mandatory with respect to any Award at the time such Award is made
to a Participant.

         If at the time an ISO is exercised the Committee determines that the
Company could be liable for withholding requirements with respect to a
disposition of the Stock received upon exercise, the Committee may require as a
condition of exercise that the person exercising the ISO agree (a) to inform the
Company promptly of any disposition (within the meaning of section 424(c) of the
Code) of Stock received upon exercise, and (b) to give such security as the
Committee deems adequate to meet the potential liability of the Company for the
withholding requirements and to augment such security from time to time in any
amount reasonably deemed necessary by the Committee to preserve the adequacy of
such security.

         8.5.  TRANSFERABILITY OF AWARDS.

         No Award (other than an Award in the form of an outright transfer of
cash or Unrestricted Stock) may be transferred other than by will or by the laws
of descent and distribution, and during an employee's lifetime an Award
requiring exercise may be exercised only by the Participant (or in the event of
the Participant's incapacity, the person or persons legally appointed to act on
the Participant's behalf), except that Options awarded to Employees or members
of the Board which are not ISOs may be transferred by a Participant to (i) the
spouse, children or grandchildren of the Participant ("Immediate Family
Members"), (ii) a trust or trusts for the exclusive benefit of such Immediate
Family Members, or (iii) a partnership in which such Immediate Family Members
are the only partners, provided that (x) there may be no consideration for any
such transfer, and (y) subsequent transfers of Options shall be prohibited
except those in accordance with Section 8.5 hereof. Following any such transfer,
the transferred Option shall continue to be subject to all the terms and
conditions of this Plan, including without limitation the provisions of Section
7 with respect to exercise of the Option following the death or termination of
employment of the Participant to whom the Option was originally granted, and
Section 8.4 with respect to tax withholding.

         8.6.  ADJUSTMENTS IN THE EVENT OF CERTAIN TRANSACTIONS.

         (a) In the event of a stock dividend, stock split or combination of
shares, recapitalization or other change in the Company's capitalization, or
other distribution to common stockholders other than normal cash dividends,
after the effective date of the Plan, the Committee will make any appropriate
adjustments to the maximum number of shares that may be delivered under the
Plan, or with respect to which Awards may be made to any one Participant, under
Section 4 above.

         (b) In any event referred to in paragraph (a), the Committee will also
make any appropriate adjustments to the number and kind of shares of stock or
securities subject to Awards then outstanding or subsequently granted, any
exercise prices relating to Awards and any other provision of Awards affected by
such change. The Committee may also make such adjustments to take into account
material changes in law or in accounting practices or principles, mergers,
consolidations, acquisitions, dispositions or similar corporate transactions, or
any other event, if it is determined by the Committee that adjustments are
appropriate to avoid distortion in the operation of the Plan.

         8.7.  EMPLOYMENT RIGHTS, ETC.

         Neither the adoption of the Plan nor the grant of Awards will confer
upon any person any right to continued retention by the Company or any
subsidiary as an Employee or otherwise, or affect in any way the right of the
Company or subsidiary to terminate an employment, service or similar
relationship at any time. Except as specifically provided by the Committee in
any particular case, the loss of existing or potential profit in Awards granted
under the Plan will not constitute an element of damages in the event of
termination of an employment, service or similar relationship even if the
termination is in violation of an obligation of the Company to the Participant.

         8.8.  DEFERRAL OF PAYMENTS.

         The Committee may agree at any time, upon request of the Participant,
to defer the date on which any payment under an Award will be made.

         8.9. PAST SERVICES AS CONSIDERATION.

         Where a Participant purchases Stock under an Award for a price equal to
the par value of the Stock the Committee may determine that such price has been
satisfied by past services rendered by the Participant.

9.   EFFECT, DISCONTINUANCE, CANCELLATION, AMENDMENT AND TERMINATION

     Neither adoption of the Plan nor the grant of Awards to a Participant will
affect the Company's right to grant to such Participant awards that are not
subject to the Plan, to issue to such Participant Stock as a bonus or otherwise,
or to adopt other plans or arrangements under which Stock may be issued to
Employees.

     The  Committee  may at any time or times amend the Plan or any  outstanding
Award for any purpose  which may at the time be  permitted by law, or may at any
time  terminate  the Plan as to any  further  grants of  Awards,  provided  that
(except to the  extent  expressly  required  or  permitted  by the Plan) no such
amendment  will,  without  the  approval  of the  stockholders  of the  Company,
effectuate a change for which stockholder  approval is required in order for the
Plan to continue to qualify for the award of ISOs under section 422 of the Code.



© 2022 IncJournal is not affiliated with or endorsed by the U.S. Securities and Exchange Commission