UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
Information statement pursuant to Rule 13d-1 and 13d-2
(Amendment No. _____)*
MacroChem Corporation
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(Name of Issuer)
Common Stock, 0.01 par value per share
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(Title of Class of Securities)
556007 10 5
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(CUSIP Number)
Check the following box if a fee is being paid with the statement _____. A fee
is not required only if the reporting person: (1) has a previous statement on
file reporting beneficial ownership of more than five percent of the class of
securities described in Item 1; and (2) has filed no amendment subsequent
thereto reporting beneficial ownership of five percent or less of such class.)
(See Rule 13d-7.)
(Continued on following page(s))
* The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter
disclosures provided in a prior cover page. The information required on the
remainder of this cover page shall not be deemed to be "filed" for the purpose
of Section 18 of the Securities Exchange Act of 1934 or otherwise subject to the
liabilities of that section of the Act but shall be subject to all other
provisions of the Act (however, see the Notes).
<PAGE>
CUSIP No. 556007 10 5 13G Page 2 of 5 Pages
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1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Pierrette E. Samour ###-##-####
- --------------------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
(a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3. SEC USE ONLY
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4. CITIZENSHIP OR PLACE OF ORGANIZATION
United States
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5. SOLE VOTING POWER
NUMBER OF SHARES 439,710
BENEFICIALLY ---------------------------------------------------
OWNED BY EACH 6. SHARED VOTING POWER
REPORTING -0-
PERSON ---------------------------------------------------
WITH 7. SOLE DISPOSITIVE POWER
REPORTING 439,710
---------------------------------------------------
8. SHARED DISPOSITIVE POWER
-0-
- --------------------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING
PERSON 439,710
- --------------------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
PERSON [ ]
- --------------------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
2.0%
- --------------------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
IN
- --------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
Page 3 of 5 Pages
Item 1 (a). Name of Issuer:
MacroChem Corporation
(b). Address of Issuer's Principal Executive Offices:
110 Hartwell Avenue
Lexington, MA 02173
Item 2 (a). Name of Person Filing:
Pierrette E. Samour
(b). Address of Principal Business Office, or , if None, Residence:
110 Hartwell Avenue
Lexington, MA 02173
(c). Citizenship:
United States
(d). Title of Class of Securities:
Common Stock, $0.01 par value per share
(e). CUSIP Number:
556007 10 5
Item 3. If this statement is filed pursuant to Rules 13d-1(b) or 13d-2(b),
check whether the person filing is a:
(a) [ ] Broker or dealer registered under Section 15 of the Act,
(b) [ ] Bank as defined in Section 3(a) (6) of the Act,
(c) [ ] Insurance Company as defined in Section 3(a)(19)of the Act,
(d) [ ] Investment Company registered under Section 8 of the
Investment Company Act,
(e) [ ] Investment Adviser registered under Section 203 of the
Investment Advisers Act of 1940,
(f) [ ] Employee Benefit Plan, Pension Fund which is subject to the
provisions of the Employee Retirement Income Security Act of
1974 or Endowment Fund; see Rule 13-d-1(b)(1)(ii)(F),
(g) [ ] Parent Holding Company, in accordance with Rule 13d-
1(b)(ii)(G); see Item 7,
(h) [ ] Group, in accordance with Rule 13d-1(b)(1)(ii)(H).
<PAGE>
Page 4 of 5 Pages
Item 4. Ownership
(a) Amount Beneficially Owned:
See Item 9 of Cover Page
(b) Percent of Class
See Item 11 of Cover Page
(c) Number of shares as to which such person has:
(i) Sole power to vote or to direct the vote
See Item 5 of Cover Page
(ii) Shared power to vote or to direct the vote
See Item 6 of Cover Page
(iii) Sole power to dispose or to direct the disposition of
See Item 7 of Cover Page
(iv) Shared power to dispose or to direct the disposition of
See Item 8 of Cover Page
Item 5. Ownership of Five Percent or Less of a Class:
[X] Statement is being filed to report the fact
that as of the date hereof the reporting
person has ceased to be the beneficial owner
of more than five percent of the class of
securities.
Item 6. Ownership of More than Five Percent on Behalf of Another Person:
Not applicable to reporting person.
Item 7. Identification and Classification of the Subsidiary Which Acquired
the Security Being Reported on by the Parent Holding Company:
Not applicable to reporting person.
Item 8. Identification and Classification of Members of the Group:
Not applicable to reporting person.
Item 9. Notice of Dissolution of Group:
Not applicable to reporting person.
Item 10. Certification:
Not applicable to reporting person.
<PAGE>
Page 5 of 5 Pages
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.
Date: January 23, 1998
By:/s/ Pierrette E. Samour
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Treasurer & Secretary
