MACROCHEM CORP
SC 13D, 1998-04-01
PHARMACEUTICAL PREPARATIONS
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SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 13D

Under the Securities Exchange Act of 1934
(Amendment No.    )*

Macrochem Corp 
_______________________________________________________________________
(Name of Issuer)

					Common Stock
________________________________________________________________________
(Title of Class of Securities)

					555903103	
________________________________________________________________________
(CUSIP Number)

Paul Byrne c/o Janssen-Meyers Associates, L.P.
17 State Street, NY, NY  10004 (212) 742-4200
_______________________________________________________________________
(Name, Address and Telephone Number of Person Authorized to 
Receive Notices and Communications)
March, 1998
________________________________________________________________________
(Date of Event which Requires Filing of this Statement)


If the filing person has previously filed a statement on Schedule 13G to 
report the acquisition which is the subject of this Schedule 13D, and is 
filing this schedule because of Rule 13d-1(b)(3) or (4), check the
 following box_____.

Check the following box if a fee is being paid with the statement _____.  
(A fee is not required only if the reporting person: (1) has a previous
 statement 
on file reporting beneficial ownership of more than five percent of the
 class of 
securities described in Item1; and (2)  has filed no amendment subsequent
 thereto 
reporting beneficial ownership of five percent of less of such class.)  
 (Sec Rule 13d-7.)

Note:  Six copies of this statement, including all exhibits, should be
 filed with 
the Commission.  See Rule 13d-1(a) for other parties to whom copies are to be
 sent.

*The remainder of this cover page shall be filled out for a reporting person's
 initial filing on this form with respect to the subject class of securities,
 and for 
any subsequent amendment containing information which would alter
 disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be
 deemed to be "filed" for the purpose of Section 18 of the Securities 
Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of
 that section of the Act but shall be subject to all other provisions of the 
Act (however, see the Notes).








1. Name of Reporting Person
Peter Janssen
_____________________________________________________
S.S. or I.R.S. Identification No. of Above Person
						
	_____________________________________________________


2. Check the Appropriate Box if a Member of a Group 
(See Instructions before filling out)

a.________	b_______

	

3. SEC USE ONLY

_____________________________________________________

4. Source of Funds (See instructions before filling out).

______________________________________________________

5. Check Box if Disclosure of Legal Proceedings is Required 
Pursuant to Items           
     2(d) or 2(e).		

	_____________________________________________________________________________

6. Citizenship or Place of Organization
 						USA
____________________________________________________

NUMBER OF SHARES BENEFICIALLY OWNED BY EACH 
REPORTING PERSON
(Questions 7 - 10)

7.  Sole Voting Power
1,554,167
____________________________________________________

8. Shared Voting Power

_____________________________________________________

9. Sole Dispositive Power
1,554,167
_____________________________________________________

10. Shared Dispositive Power
                                                                
_____________________________________________________

11.  Aggregate Amount Beneficially Owned by Each 
Reporting Person
						1,554,167
_____________________________________________________

12.  Check Box if the Aggregate Amount in Row (11) Excludes 
Certain Shares (See instructions before filling out)

_____________________________________________________



13. Percent of Class Represented by Amount in Row (11)

_______________________7%_______________________________

14. Type of Reporting Person (See instructions before filling out)

______________________________________________________



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