PRUDENTIAL MUNICIPAL SERIES FUND
N-30D, 1994-11-25
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ANNUAL REPORT                          August 31, 1994

Prudential
Municipal
Series Fund

(ICON)

Arizona Series

(LOGO)

<PAGE>

Letter to Shareholders

October 18, 1994 

Dear Shareholder:

It has been a most difficult year in the U.S. financial markets.  When we 
last wrote in February  interest rates were starting to rise, ending a 
three-year long bull market in bonds. What started as a trickle has 
become a torrent.  Interest rates have continued to increase this 
year, sending bond prices down sharply.  Of course, as interest 
rates rise, bond prices decline.  In this environment of falling 
prices and unusual volatility, your Prudential Municipal Series 
Fund -- Arizona Series sought to minimize risk while maximizing 
your tax-free income.

The Series seeks maximum income exempt from Arizona and federal income 
taxes* consistent with preservation of capital.  The Series is 
comprised of investment grade municipal obligations with an 
average credit quality of Aa/AA, as determined by Moody's Investors 
Service or Standard & Poor's Rating Group.  The Series performed in 
line with the Lipper Arizona Municipal Debt Average over the last year, 
but because long-term interest rates rose, total returns were disappointing.
As a result, the Series has become more cautious and shortened its 
average maturity.

<TABLE>
                          SERIES PERFORMANCE 
                         As of August 31, 1994
<CAPTION>
                      30-day           Taxable Equivalent Yields   
               NAV   SEC Yield            @28%   @31%   @39.6%
<S>          <C>       <C>                <C>    <C>     <C>
Class A      $11.59    4.5%               6.7%   7.0%    8.0%
Class B      $11.58    4.3%               6.4%   6.6%    7.6% 
Class C      $11.58    N/A                N/A    N/A     N/A
</TABLE>

Investment return and principal value will fluctuate so that an 
investor's shares, when redeemed, may be worth more or less than 
their original cost.  Past performance is no guarantee of future results.

*Interest on municipal obligations may be subject to the federal 
alternative minimum tax.  See your Series' prospectus for more details.

                                   -1-

<PAGE>
<TABLE>
                             TOTAL RETURNS
<CAPTION>
                     Historical (As of 8/31/94)1    Average Annual (As of 9/30/94)2
                    1-Yr.   5-Yr.  Since Incep.**   1-Yr.   5-Yr.   Since Incep.**
<S>                <C>      <C>     <C>             <C>     <C>        <C>
Class A            -0.6%    N/A      +40.5%         -5.8%    N/A       +6.6%
Class B            -1.1%   +41.5%   +126.1%         -8.2%   +7.0%      +8.4%
Class C             N/A     N/A       +0.1%           N/A    N/A       -1.9%
Lipper AZ 
Muni Debt Avg.***  -1.2%   +44.9%   +122.8%           N/A    N/A        N/A   
</TABLE>

 Source: Lipper Analytical Services, Inc. These figures do not take into 
account sales charges.

2 Source: Prudential Mutual Fund Management, Inc.  These averages take 
into account applicable sales charges.  The Series charges a maximum 
initial sales charge of 3% for Class A shares.  Class B shares are 
subject to a declining contingent deferred sales charge of 5%, 4%, 
3%, 2%, 1% and 1%, respectively, for the first six years.  Class B 
shares will automatically convert to Class A shares approximately 
seven years after purchase.  This conversion feature is expected to 
be implemented in February 1995. Class C shares are subject to a 
contingent deferred sales charge of 1% during the first year. 

**Inception on January 22, 1990 for Class A, September 22, 1984 for 
Class B and August 1, 1994 for Class C.

***These are the average returns of 27 Arizona municipal debt funds 
for one-year, five-year, and since inception of Class B shares, as 
determined by Lipper Analytical Services, Inc.

Note:  Without expense subsidies and management fee waivers, the 
Series' historical and average annual total returns would have been 
lower.  The Series' Class B average annual total return since 
inception would have been 8.3%.

Once Was Not Enough

In February, the Federal Reserve raised short-term interest rates for 
the first time in years, hoping to control inflation.  Since then, the 
Fed has moved four more times, until the federal funds rate (the overnight 
interbank lending rate) now stands at 4.75%, up from 3% at the 
start of the year. The Fed also increased the discount rate (the 
bank lending rate) to 4% from 3% over the same period.

Interest rates rise when the financial markets fear inflation, the 
bond holder's enemy. Inflation is feared because it robs purchasing 
power from a bond's fixed-interest rate.

Municipal bond interest rates increased by more than a percentage 
point, to 6.46% on August 25 from 5.52% on December 29, 1993, as 
measured by the Bond Buyer's Revenue Bond Index, a widely used 
yardstick of interest rates in the tax-free market.

Arizona: Economy Growing Rapidly

The Arizona economy is among the fastest growing in the nation.  
In Phoenix, population and employment increases have reached levels 
not seen since the boom times of the mid-1980s.   From 1983 to 1993, 
the state's population has grown by nearly 33%.  Arizona's 
population is the third fastest growing 

                                -2-

<PAGE>

in the nation after Nevada and Colorado, and in employment, the 
state is second only to Georgia in growth.

Not surprisingly, state finances are in excellent condition.  Fiscal 
1994 revenues came in $179 million ahead of already upwardly revised 
estimates, so the legislature voted to cut income taxes by $100 million 
in its 1995 budget. 

The only question mark on the horizon is political.  Running for 
reelection in November, Governor Symington has pledged to phase out 
the state's income tax over a four-year period should he be reelected.  
This would reduce revenues by $1.5 billion.  The governor argues 
that the growing economy, and particularly the stimulus of the tax 
cut, would make up for the shortfall, a position subject to some debate.

With new issues down 54% to date this year in Arizona, bonds have 
been scarce.  We have remained fully invested, anticipating this 
drought will continue through the year.

A Tax Reminder

As a result of the federal Revenue Reconciliation Act of 1993, which 
affects bonds purchased after April 30, 1993,  it is possible that 
this year you may have some taxable income from your tax-free municipal 
bond fund.  The law stipulates that the portion of any gain realized on 
the sale or retirement of a tax-free bond purchased at a market discount 
to its face value must be taxed as ordinary income.

Following this change in federal tax law, some discount bonds have 
been selling at levels so cheap they will produce a higher after-tax 
return than other bonds not subject to the provisions of the new law.  
We have occasionally taken advantage of this market imbalance because 
we have determined that at very low prices these bonds can still provide 
you with a higher after-tax return on your investment.

The Outlook

We expect continued volatility in the municipal bond market until the 
economy reaches a level of growth that is sustainable without causing 
inflation.  If the economy continues to surge, the ever vigilant Fed 
will move again, lifting short-term rates.  If the economy slows 
substantially, long term rates should stabilize.  Although rates 
may keep rising, we believe that most of the increase is now behind us.

In the months ahead, we expect supply -- or the lack of it -- to 
become more important in the tax-free municipal bond market.  Through 
the first eight months of the year, new issue volume is off 42%, according 
to Securities Data Co., which tracks this statistic.  The pace is 
accelerating.  In August, new issue volume fell 56%.  

                                -3-

<PAGE>

As always, it is a pleasure to have you as a shareholder in the 
Prudential Municipal Series Fund -- Arizona Series, and to take 
this opportunity to report our activities to you.



Sincerely,

Lawrence C. McQuade
President

Christian Smith
Portfolio Manager

                                    -4-

<PAGE>

PRUDENTIAL MUNICIPAL SERIES FUND                  Portfolio of Investments
ARIZONA SERIES                                             August 31, 1994

<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                  Value 
(Unaudited)     (000)          Description (a)        (Note 1)

<C>           <C>          <S>                      <C>
                           LONG-TERM INVESTMENTS--97.6%
                           Arizona St. Edl. Loan
                             Mkt. Corp.,
A              $  1,375    7.00%, 3/1/05, Ser.
                             B....................  $  1,453,334
                           Arizona St. Hsg. Fin.
                             Review Brd.,
                           Sngl. Fam. Mtge. Rev.,
A-*                  10    10.625%, 12/1/02, Ser.
                             82...................        10,310
                           Arizona St. Mun. Fin.
                             Proj.,
                           Cert. of Part.,
                           8.75%, 8/1/06, Ser. 15,
Aaa                 700    B.I.G..................       749,014
                           7.875%, 8/1/14, Ser.
                             25,
Aaa               2,250    A.M.B.A.C..............     2,724,412
                           Arizona St. Trans. Brd.
                             Hwy. Rev.,
Aaa               2,000(D)@ 7.00%, 7/1/09..........    2,216,100
Aa                1,500(D) 6.00%, 7/1/10..........     1,587,765
                           Arizona St. Univ. Sys.
                             Rev.,
Aaa               1,000(D) 7.00%, 7/1/10, Ser.
                             A....................     1,121,880
                           Central Arizona Wtr.
                             Consv. Dist.,
                             Contract Rev.,
A1                1,500(D) 7.50%, 11/1/05.........     1,716,285
                           Chandler, Cap. Apprec.
                             Ref.,
Aaa               2,000    Zero Coupon, 7/1/02,
                             F.G.I.C..............     1,318,500
                           Gen. Oblig.,
Aaa                 500    4.375%, 7/1/13,
                             F.G.I.C..............       399,390
                           La Paz Cnty., Unified
                             Sch. Dist.,
                           No. 27, Parker Impvt.
                             Proj.,
Baa                 450    9.40%, 7/1/96..........       483,728
                           Maricopa Cnty. Hosp.
                             Dist. No. 1, Facs.
                             Rev.,
                             East Valley
                             Behavioral
                             Hlth. Fac. Proj.,
Aaa                 725(D) 7.80%, 6/1/13,
                             F.G.I.C..............       796,804
                           Maricopa Cnty. Ind.
                             Dev. Auth.
                           Hosp. Fac. Rev.,
                             John C. Lincoln
                             Hosp.,
Aaa               2,000    7.00%, 12/1/00,
                             F.S.A................     2,188,640
                           Maricopa Cnty. Ind.
                             Dev. Auth. Hosp. Fac.
                             Rev.,
                           Mercy Hlth.,
                           9.00%, 7/1/99, Ser. D,
Aaa            $  1,000    M.B.I.A.,..............  $  1,058,760
A1                  525(D) 9.25%, 7/1/11, Ser.
                             D....................       556,616
A1                  475    9.25%, 7/1/11, Ser.
                             D....................       500,132
                           Samaritan Hlth. Svcs.,
Aaa                 290(D) 12.00%, 1/1/08.........       341,527
                           Maricopa Cnty. Sch.
                             Dist.,
                           No. 41 Gilbert Proj.,
                           6.50%, 7/1/08, Ser. E,
Aaa               2,000(D)@ F.G.I.C................    2,170,720
                           No. 40 Glendale Elem.
                             Sch.,
                           Zero Coupon, 7/1/04,
Aaa               2,810    A.M.B.A.C..............     1,621,510
                           No. 11 Peoria Unified
                             Sch. Dist.,
                           Zero Coupon, 7/1/04,
Aaa               1,500    M.B.I.A................       865,575
                           Zero Coupon, 7/1/04,
Aaa               1,140    F.G.I.C................       657,837
                           No. 3 Tempe Elem. Sch.,
                           Zero Coupon, 7/1/09,
Aaa               1,500    A.M.B.A.C..............       595,155
                           Zero Coupon, 7/1/14,
Aaa               1,500    A.M.B.A.C..............       425,055
                           Maricopa Cnty. Unified
                             Sch. Dist.,
                           No. 80 Chandler,
                             F.G.I.C.
Aaa               1,330    Zero Coupon, 7/1/09....       527,704
Aaa               1,000    6.25%, 7/1/11..........     1,029,360
                           Navajo Cnty. Unified
                             Sch. Dist.,
                           No. 006 Herber
                             Overgaard,
Aaa                 250    7.25%, 7/1/00,
                             A.M.B.A.C............       276,285
Aaa                 300    7.35%, 7/1/03,
                             A.M.B.A.C............       332,679
                           Nogales Mun. Dev. Auth.
                             Rev.,
Aaa                 500(D)@ 8.00%, 6/1/08,
                             M.B.I.A..............       558,990
                           Peoria Bell Road Impvt.
                             Dist.,
BBB*                465    7.20%, 1/1/11..........       486,525
                           Phoenix Arpt. Rev.,
                           6.40%, 7/1/12, Ser. D,
Aaa                 810    M.B.I.A................       817,930
</TABLE>
 
                                  -5-     See Notes to Financial Statements.

<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                  
ARIZONA SERIES
<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                  Value
(Unaudited)     (000)          Description (a)        (Note 1)

<C>           <C>          <S>                      <C>
                           Phoenix Ind. Dev. Auth.
                             Hosp.,
                           John C. Lincoln Hosp.,
BBB*          $    500     6.00%, 12/1/10.........  $    467,470
BBB*               500     6.00%, 12/1/14.........       453,245
                           Phoenix St. & Hwy.
                             Rev.,
A1                1,480    6.25%, 7/1/06, Ser.
                             92...................     1,546,126
                           Zero Coupon, 7/1/12,
Aaa               3,000    F.G.I.C................       975,420
                           Pima Cnty. Ind. Dev.
                             Auth. Hlth. Care,
                             Carondelet
                             St. Josephs & Marys
                             Hosp.,
Aaa               1,000    7.90%, 7/1/05,
                             B.I.G................     1,115,350
Aaa               1,000(D) 8.00%, 7/1/13,
                             B.I.G................     1,119,170
                           Pima Cnty. Ind. Dev.
                             Auth. Rev.,
                             Tucson Elec. Pwr.
                             Co.,
Aaa               2,700    7.25%, 7/15/10,
                             F.S.A................     2,887,110
                           Pima Cnty., Unified
                             Sch. Dist.
                             No. 16, Catalina
                             Foothills,
                           Zero Coupon, 7/1/08,
Aaa               3,000    F.G.I.C................     1,290,810
                           Zero Coupon, 7/1/09,
Aaa               3,455    F.G.I.C................     1,370,840
                           Puerto Rico Hsg. Fin.
                             Auth. Rev.,
                             Multifamily Mtge.,
AA*                 835    7.50%, 4/1/22..........       869,110
                           Puerto Rico Comnwlth.
                             Hwy.
                             Auth. Rev.,
AAA*                490(D) 7.70%, 7/1/03, Ser.
                             Q....................       566,763
                           Puerto Rico, Comnwlth.,
                             Gen. Oblig.,
                           8.41%, 7/1/08, Ser. A,
Aaa               1,000(D)(D) M.B.I.A................    1,012,500
                           Salt River Proj. Agric.
                             Impvt. & Pwr. Dist.,
                             Elec. Sys. Rev.,
Aa                1,500    4.75%, 1/1/17, Ser.
                             C....................     1,218,540
Aa                  500    5.75%, 1/1/20, Ser.
                             C....................       468,960
                           Santa Cruz Cnty.
                             Unified Sch. Dist.
                             No. 1
                             Nogales, Cruz Cnty.,
                           Zero Coupon, 1/1/06,
Aaa                 770    A.M.B.A.C..............       397,051
                           Santa Cruz Cnty.,
                             Unified Sch. Dist.
                             No. 1
                             Nogales, Cruz Cnty.,
                           Zero Coupon, 7/1/06,
Aaa            $    700    A.M.B.A.C..............  $    350,560
                           Scottsdale Ind. Dev.
                             Auth. Rev., Mem.
                             Hosp.,
                           8.50%, 9/1/07, Ser. A,
Aaa               2,100    A.M.B.A.C..............     2,352,378
                           Scottsdale, Gen.
                             Oblig.,
Aa1                 500    5.50%, 7/1/09..........       479,885
Aa1               1,000(D) 6.00%, 7/1/10..........     1,066,020
Aa1               1,000    4.00%, 7/1/13, Ser.
                             D....................       737,640
                           Tempe Impvt. Dist. Auth. Rev.,
                             Papago Park Ctr.,
                             Dist. No. 166,
A1                  500    7.10%, 1/1/06..........       522,910
                           Tempe, Gen. Oblig.,
Aa                  500    5.25%, 7/1/13..........       451,190
                           Tolleson Mun. Fin. Corp. Rev.,
                             Citizen Util. Co.,
AAA*                400    9.20%, 9/1/05..........       426,812
                           Tucson Wtr. Rev.,
Aaa               1,000    8.60%, 7/1/00,
                             E.T.M................     1,179,540
A1                1,000    5.50%, 7/1/09..........       947,480
                           7.00%, 7/1/10, Ser. C,
Aaa                 500    M.B.I.A................       534,925
                           Univ. Arizona Revs.
                             Sys.,
A1                1,750    6.25%, 6/1/11, Ser.
                             B....................     1,771,438
                           Virgin Islands Pub. Fin. Auth. Rev.,
                             Hwy. Trans. Trust Fund,
NR                  600    7.25%, 10/1/18, Ser.
                             A....................       618,972
                           Virgin Islands Terr.,
                           Hugo Ins. Claims Fund
                             Prog.,
NR                  460    7.75%, 10/1/06, Ser.
                             91...................       502,978
                           Virgin Islands Wtr. &
                             Pwr. Auth., Elec.
                             Sys. Rev.,
NR                  500    7.40%, 7/1/11, Ser.
                             A....................       522,300
                           Wtr. Sys. Rev.,
NR                  500    8.50%, 1/1/10, Ser.
                             A....................       549,280
                                                    ------------
                           Total long-term
                             investments
                           (cost $55,132,298).....    58,361,295
                                                    ------------
</TABLE>
 
                                  -6-     See Notes to Financial Statements.
 
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                  
ARIZONA SERIES
<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                  Value
(Unaudited)     (000)          Description(a)         (Note 1)

<S>           <C>          <C>                      <C>
                           SHORT-TERM INVESTMENTS--1.4%
                           Goodyear, Gen. Oblig.,
Baa1           $    100    10.00%, 7/1/95.........  $    104,311
                           Pinal Cnty. Ind. Dev.
                             Auth. Hlth. Care,
                             Ctrl. Rev., F.R.D.D.,
P1                  700    3.35%, 9/1/94..........       700,000
                                                    ------------
                           Total short-term
                             investments
                           (cost $799,625)........       804,311
                                                    ------------
                           Total Investments--99.0%
                           (cost $55,931,923; Note
                             4)...................    59,165,606
                           Other assets in excess
                             of
                             liabilities--1.0%....       613,223
                                                    ------------
                           Net Assets--100%.......  $ 59,778,829
                                                    ------------
                                                    ------------
</TABLE>
 
- ------------------
(a) The following abbreviations are used in portfolio descriptions:
    A.M.B.A.C.--American Municipal Bond Assurance Corporation.
    B.I.G.--Bond Investors Guaranty Insurance Company.
    E.T.M.--Escrowed to Maturity.
    F.G.I.C.--Financial Guaranty Insurance Company.
    F.R.D.D.--Floating Rate (Daily) Demand Note#.
    F.S.A.--Financial Security Assurance.
    M.B.I.A.--Municipal Bond Insurance Association.
    # For purposes of amortized cost valuation, the
      maturity date of Floating Rate Demand Notes is
      considered to be the later of the next date on
      which the security can be redeemed at par or the
      next date on which the rate of interest is
      adjusted.
    * Standard & Poor's rating.
  (D) Prerefunded issues are secured by escrowed cash
      and/or direct U.S. guaranteed obligations.
 (D)(D)Inverse floating rate bond. The coupon is
      inversely indexed to a floating interest rate.
      The rate shown is the rate at period end.
    @ Pledged as initial margin on financial futures
     contracts.
 
NR--Not Rated by Moody's or Standard & Poor's.
The Fund's current Statement of Additional Information contains a description
of Moody's and Standard & Poor's ratings.

                                  -7-     See Notes to Financial Statements.

<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 ARIZONA SERIES
 Statement of Assets and Liabilities
<TABLE>
<CAPTION>
Assets                                                                                    August 31, 1994
                                                                                          ---------------
<S>                                                                                    <C>
Investments, at value (cost $55,931,923).................................................     $59,165,606
Cash.....................................................................................          83,991
Interest receivable......................................................................         737,249
Receivable for Fund shares sold..........................................................          21,467
Other assets.............................................................................           1,869
                                                                                            ---------------
  Total assets...........................................................................      60,010,182
                                                                                            ---------------
Liabilities
Accrued expenses.........................................................................          66,324
Payable for Fund shares reacquired.......................................................          57,677
Dividends payable........................................................................          49,717
Management fee payable...................................................................          25,227
Distribution fee payable.................................................................          22,648
Due to broker-variation margin payable...................................................           8,750
Deferred trustee fees....................................................................           1,010
                                                                                            ---------------
  Total liabilities......................................................................         231,353
                                                                                            ---------------
Net Assets...............................................................................     $59,778,829
                                                                                            ---------------
                                                                                            ---------------
Net assets were comprised of:
  Shares of beneficial interest, at par..................................................     $    51,601
  Paid-in capital in excess of par.......................................................      56,542,821
                                                                                            ---------------
                                                                                               56,594,422
  Distributions in excess of net realized gains..........................................         (25,526)
  Net unrealized appreciation of investments.............................................       3,209,933
                                                                                            ---------------
  Net assets, August 31, 1994............................................................     $59,778,829
                                                                                            ---------------
                                                                                            ---------------
Class A:
  Net asset value and redemption price per share ($7,674,526 / 662,409 shares of
    beneficial interest issued and outstanding)..........................................            $11.59
  Maximum sales charge (3.0% of offering price)..........................................               .36
                                                                                            ---------------
  Maximum offering price to public.......................................................            $11.95
                                                                                            ---------------
                                                                                            ---------------
Class B:
  Net asset value, offering price and redemption price per share ($52,104,103 / 4,497,713
    shares of beneficial interest issued and outstanding)................................            $11.58
                                                                                            ---------------
                                                                                            ---------------
Class C:
  Net asset value, offering price and redemption price per share ($199.97 / 17.262 shares
    of beneficial interest issued and outstanding).......................................            $11.58
                                                                                            ---------------
                                                                                            ---------------
</TABLE>
 
See Notes to Financial Statements.
                                      -8-
 
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 ARIZONA SERIES
 Statement of Operations
<TABLE>
<CAPTION>
                                           Year Ended
Net Investment Income                    August 31, 1994
                                         ---------------
<S>                                      <C>
Income
  Interest............................     $   3,939,686
                                         ---------------
Expenses
  Management fee......................           313,334
  Distribution fee--Class A...........             7,141
  Distribution fee--Class B...........           277,628
  Custodian's fees and expenses.......            52,000
  Reports to shareholders.............            37,500
  Transfer agent's fees and
  expenses............................            33,000
  Registration fees...................            20,000
  Legal fees..........................            15,000
  Audit fee...........................            10,500
  Trustees' fees......................             3,375
  Miscellaneous.......................             7,770
                                         ---------------
    Total expenses....................           777,248
                                         ---------------
Net investment income.................         3,162,438
                                         ---------------
Realized and Unrealized
Gain (Loss) on Investments
Net realized gain (loss) on:
  Investment transactions.............           790,344
  Financial futures contract
  transactions........................           (32,841)
                                         ---------------
                                                 757,503
                                         ---------------
Net change in unrealized
  appreciation/depreciation of:
  Investments.........................        (4,562,693)
  Financial futures contracts.........           (22,813)
                                         ---------------
                                              (4,585,506)
                                         ---------------
Net loss on investments...............        (3,828,003)
                                         ---------------
Net Decrease in Net Assets
Resulting from Operations.............     $    (665,565)
                                         ---------------
                                         ---------------
</TABLE>

                      See Notes to Financial Statements.

 PRUDENTIAL MUNICIPAL SERIES FUND
 ARIZONA SERIES
 Statement of Changes in Net Assets
<TABLE>
<CAPTION>
                               Year Ended August 31,
Increase (Decrease)         ---------------------------
in Net Assets                   1994           1993
                            ------------    -----------
<S>                         <C>             <C>
Operations
  Net investment income...  $  3,162,438    $ 2,979,801
  Net realized gain on
    investment
    transactions..........       757,503        175,821
  Net change in unrealized
    appreciation of
    investments...........    (4,585,506)     3,112,559
                            ------------    -----------
  Net increase (decrease)
    in net assets
    resulting from
    operations............      (665,565)     6,268,181
                            ------------    -----------
Dividends and
  distributions (Note 1):
  Dividends from net
    investment income
    Class A...............      (386,495)      (201,649)
    Class B...............    (2,775,943)    (2,778,152)
                            ------------    -----------
                              (3,162,438)    (2,979,801)
                            ------------    -----------
  Distributions from net
    realized gains
    Class A...............       (74,328)       (21,305)
    Class B...............      (618,468)      (500,545)
                            ------------    -----------
                                (692,796)      (521,850)
                            ------------    -----------
Series share transactions
  (Note 5)
  Net proceeds from shares
    sold..................    10,037,346     12,302,375
  Net asset value of
    shares issued in
    reinvestment of
    dividends and
    distributions.........     2,064,510      1,717,602
  Cost of shares
  reacquired..............   (11,709,424)    (6,722,273)
                            ------------    -----------
  Net increase in net
    assets from Series
    share transactions....       392,432      7,297,704
                            ------------    -----------
Total increase
  (decrease)..............    (4,128,367)    10,064,234
Net Assets
Beginning of year.........    63,907,196     53,842,962
                            ------------    -----------
End of year...............  $ 59,778,829    $63,907,196
                            ------------    -----------
                            ------------    -----------
</TABLE>
 
                       See Notes to Financial Statements.
                                      -9-
 
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 ARIZONA SERIES
 Notes to Financial Statements

   Prudential Municipal Series Fund (the ``Fund'') is registered under the
Investment Company Act of 1940, as an open-end investment company. The Fund was
organized as a Massachusetts business trust on May 18, 1984 and consists of
seventeen series. The monies of each series are invested in separate,
independently managed portfolios. The Arizona Series (the ``Series'') commenced
investment operations in September, 1984. The Series is diversified and seeks to
achieve its investment objective of obtaining the maximum amount of income
exempt from federal and applicable state income taxes with the minimum of risk
by investing in ``investment grade'' tax-exempt securities whose ratings are
within the four highest ratings categories by a nationally recognized
statistical rating organization or, if not rated, are of comparable quality. The
ability of the issuers of the securities held by the Series to meet their
obligations may be affected by economic or political developments in a specific
state, industry or region.
                              
Note 1. Accounting            The following is a summary
Policies                      of significant accounting poli-
                              cies followed by the Fund, and the Series, in the
preparation of its financial statements.

Securities Valuations: The Fund values municipal securities (including
commitments to purchase such securities on a ``when-issued'' basis) on the basis
of prices provided by a pricing service which uses information with respect to
transactions in bonds, quotations from bond dealers, market transactions in
comparable securities and various relationships between securities in
determining values. If market quotations are not readily available from such
pricing service, a security is valued at its fair value as determined under
procedures established by the Trustees.

   Short-term securities which mature in more than 60 days are valued at current
market quotations. Short-term securities which mature in 60 days or less are
valued at amortized cost.

   All securities are valued as of 4:15 P.M., New York time.

Financial Futures Contracts: A financial futures contract is an agreement to
purchase (long) or sell (short) an agreed amount of debt securities at a set
price for delivery on a future date. Upon entering into a financial futures
contract, the Series is required to pledge to the broker an amount of cash
and/or other assets equal to a certain percentage of the contract amount. This
amount is known as the ``initial margin''. Subsequent payments, known as
``variation margin'', are made or received by the Series each day, depending on
the daily fluctuations in the value of the underlying security. Such variation
margin is recorded for financial statement purposes on a daily basis as
unrealized gain or loss. The Series invests in financial futures contracts
solely for the purpose of hedging its existing portfolio securities or
securities the Series intends to purchase against fluctuations in value caused
by changes in prevailing market conditions. Should market conditions move
unexpectedly, the Series may not achieve the anticipated benefits of the
financial futures contracts and may realize a loss. The use of futures
transactions involves the risk of imperfect correlation in movements in the
price of futures contracts, interest rates and the underlying hedged assets.

Securities Transactions and Investment Income: Securities transactions are
recorded on the trade date. Realized gains and losses on sales of securities are
calculated on the identified cost basis. Interest income is recorded on the
accrual basis. The Series amortizes premiums and original issue discount paid on
purchases of portfolio securities as adjustments to interest income.

   Net investment income (other than distribution fees) and unrealized and
realized gains or losses are allocated daily to each class of shares based upon
the relative proportion of net assets of each class at the beginning of the day.

Federal Income Taxes: For federal income tax purposes, each series in the Fund
is treated as a separate taxpaying entity. It is the intent of the Series to
continue to meet the requirements of the Internal Revenue Code applicable to
regulated investment companies and to distribute all of its net income to
shareholders. For this reason and because substantially all of the Series' gross
income consists of tax-exempt interest, no federal income tax provision is
required.

Dividends and Distributions: The Series declares daily dividends from net
investment income. Payment of dividends is made monthly. Distributions of net
capital gains, if any, are made annually.

   Income distributions and capital gain distributions are determined in
accordance with income tax regulations which may differ from generally accepted
accounting principles.
                                      -10-

<PAGE>
                              
Note 2. Agreements            The Fund has a management
                              agreement with Prudential Mutual Fund Management,
Inc. (``PMF''). Pursuant to this agreement, PMF has responsibility for all
investment advisory services and supervises the subadviser's performance of such
services. PMF has entered into a subadvisory agreement with The Prudential
Investment Corporation (``PIC''); PIC furnishes investment advisory services in
connection with the management of the Fund. PMF pays for the services of PIC,
the compensation of officers of the Fund, occupancy and certain clerical and
bookkeeping costs of the Fund. The Fund bears all other costs and expenses.

   The management fee paid PMF is computed daily and payable monthly, at an
annual rate of .50 of 1% of the average daily net assets of the Series.

   The Fund has distribution agreements with Prudential Mutual Fund
Distributors, Inc. (``PMFD''), which acts as the distributor of the Class A
shares of the Fund, and with Prudential Securities Incorporated (``PSI''), which
acts as distributor of the Class B and Class C shares of the Fund (collectively
the ``Distributors''). The Fund compensates the Distributors for distributing
and servicing the Fund's Class A, Class B and Class C shares, pursuant to plans
of distribution (the ``Class A, B and C Plans''), regardless of expenses
actually incurred by them. The distribution fees are accrued daily and payable
monthly.

   On July 19, 1994, shareholders of the Fund approved amendments to the Class A
and Class B distribution plans under which the distribution plans became
compensation plans, effective August 1, 1994. Prior thereto, the distribution
plans were reimbursement plans, under which PMFD and PSI were reimbursed for
expenses actually incurred by them up to the amount permitted under the Class A
and Class B Plans, respectively. The Fund is not obligated to pay any prior or
future excess distribution costs (costs incurred by the Distributors in excess
of distribution fees paid by the Fund or contingent deferred sales charges
received by the Distributors). The rate of the distribution fees charged to
Class A and Class B shares of the Fund did not change under the amended plans of
distribution. The Fund began offering Class C shares on August 1, 1994.

   Pursuant to the Class A, B and C Plans, the Fund compensates the Distributors
for distribution-related activities at an annual rate of up to .30 of 1%, .50 of
1% and 1%, of the average daily net assets of the Class A, B and C shares,
respectively. Such expenses under the Plans were .10 of 1%, .50 of 1% and .75 of
1% of the average daily net assets of the Class A, B and C shares, respectively,
for the fiscal year ended August 31, 1994.

   PMFD has advised the Series that it has received approximately $63,200 in
front-end sales charges resulting from sales of Class A shares during the fiscal
year ended August 31, 1994. From these fees, PMFD paid such sales charges to PSI
and Pruco Securities Corporation, affiliated broker-dealers, which in turn paid
commissions to salespersons and incurred other distribution costs.

   PSI has advised the Series that for the fiscal year ended August 31, 1994, it
received approximately $76,800 in contingent deferred sales charges imposed upon
certain redemptions by Class B shareholders.

   PMFD is a wholly-owned subsidiary of PMF; PSI, PMF and PIC are indirect,
wholly-owned subsidiaries of The Prudential Insurance Company of America.
                              
Note 3. Other                 Prudential Mutual Fund Ser-
Transactions                  vices, Inc. (``PMFS''), a 
with Affiliates               wholly-owned subsidiary of 
                              PMF, serves as the Fund's transfer agent. During
the year ended August 31, 1994, the Series incurred fees of approximately
$23,600 for the services of PMFS. As of August 31, 1994, approximately $1,900 of
such fees were due to PMFS. Transfer agent fees and expenses in the Statement of
Operations include certain out-of-pocket expenses paid to non-affiliates.
                              
Note 4. Portfolio             Purchases and sales of port-
Securities                    folio securities of the Series, 
                              excluding short-term investments, for the year
ended August 31, 1994 were $20,412,123 and $21,899,033, respectively.

   The cost basis of investments for federal income tax purposes is
substantially the same as for financial reporting purposes and, accordingly, as
of August 31, 1994, net unrealized appreciation of investments, including
short-term investments, for federal income tax purposes is $3,233,683 (gross
unrealized appreciation--$4,247,842 gross unrealized depreciation--$1,014,159).
   At August 31, 1994, the Series sold 35 financial futures contracts on the
Municipal Bond Index expiring in September 1994. The value at disposition of
such contracts is $3,606,406. The value of such contracts on August 31, 1994 was
$3,630,156, thereby resulting in an unrealized loss of $23,750.

                              
Note 5. Capital               The Series currently offers
                              Class A, Class B and Class C shares. Class A
shares are sold with a front-end sales charge of up to 3.0%. Class B shares are
sold with a contingent deferred sales charge which declines from 5% to zero
depending on the period of time the shares are held. Class C

                                      -11-

<PAGE>
shares are sold with a contingent deferred sales charge of 1% during the first
year. Class B shares will automatically convert to Class A shares on a quarterly
basis approximately seven years after purchase commencing in or about February
1995.

   The Fund has authorized an unlimited number of shares of beneficial interest
of each class at $.01 par value per share. Transactions in shares of beneficial
interest for the fiscal years ended August 31, 1993 and 1994 were as follows:
<TABLE>
<CAPTION>
Class A                             Shares        Amount
- --------------------------------   --------    ------------
<S>                                <C>         <C>
Year ended August 31, 1994:
Shares sold.....................    156,225    $  1,879,629
Shares issued in reinvestment of
  dividends and distributions...     29,257         350,410
Shares reacquired...............    (55,416)       (665,858)
                                   --------    ------------
Net increase in shares
  outstanding...................    130,066    $  1,564,181
                                   --------    ------------
                                   --------    ------------
Year ended August 31, 1993:
Shares sold.....................    379,867    $  4,588,716
Shares issued in reinvestment of
  dividends and distributions...     10,501         127,266
Shares reacquired...............    (38,736)       (459,132)
                                   --------    ------------
Net increase in shares
  outstanding...................    351,632    $  4,256,850
                                   --------    ------------
                                   --------    ------------
<CAPTION>
Class B                             Shares        Amount
- --------------------------------   --------    ------------
<S>                                <C>         <C>
Year ended August 31, 1994:
Shares sold.....................    679,458    $  8,157,517
Shares issued in reinvestment of
  dividends and distributions...    142,601       1,714,100
Shares reacquired...............   (930,146)    (11,043,566)
                                   --------    ------------
Net decrease in shares
  outstanding...................   (108,087)   $ (1,171,949)
                                   --------    ------------
                                   --------    ------------
Year ended August 31, 1993:
Shares sold.....................    639,982    $  7,713,659
Shares issued in reinvestment of
  dividends and distributions...    132,586       1,590,336
Shares reacquired...............   (520,539)     (6,263,141)
                                   --------    ------------
Net increase in shares
  outstanding...................    252,029    $  3,040,854
                                   --------    ------------
                                   --------    ------------
<CAPTION>
Class C
- --------------------------------
<S>                                <C>         <C>
August 1, 1994* through
  August 31, 1994:
Shares sold.....................         17    $        200
                                   --------    ------------
Net increase in shares
  outstanding...................         17    $        200
                                   --------    ------------
                                   --------    ------------
</TABLE>
 
- ---------------
* Commencement of offering of Class C shares.

                                      -12-

<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 ARIZONA SERIES
 Financial Highlights
<TABLE>
<CAPTION>
                                  Class A                                              Class B                       Class C
           -----------------------------------------------------  ------------------------------------------------  -----------
                                                     January 22,                                                       August 1,
                                                       1990(D)                                                        1994(D)(D)
                    Year Ended August 31,              through                  Year Ended August 31,                   through
           ---------------------------------------   August 31,    ------------------------------------------------   August 31,
               1994        1993     1992     1991       1990         1994      1993      1992      1991      1990        1994

<S>        <C>            <C>      <C>      <C>      <C>           <C>        <C>       <C>       <C>       <C>       <C>
           ------------   ------   ------   ------   -----------   --------   -------   -------   -------   -------   -----------
<CAPTION>
PER SHARE
OPERATING
  PERFORMANCE:

Net asset value,
  beginning
  of period... $12.44      $11.88   $11.32   $10.80     $ 10.99@    $ 12.44    $ 11.87   $ 11.32   $ 10.80   $ 10.97     $ 11.60
               ------      ------   ------   ------   -----------   --------   -------   -------   -------   -------   -----------
Income from
  investment
  operations

Net
  investment
  income...       .65         .67      .68      .69         .42         .60        .62       .63       .64       .65         .04

Net realized
  and unrealized
  gain (loss)
  on investment
  transactions.. (.72)        .68      .56     .52         (.19)@      (.73)       .69       .55       .52      (.17)       (.02)
                ------     ------   ------   ------   -----------   --------   -------   -------   -------   -------   -----------
  Total
  from
  investment
  operations...  (.07)       1.35     1.24     1.21         .23@       (.13)      1.31      1.18      1.16       .48         .02
                ------     ------   ------   ------   -----------   --------   -------   -------   -------   -------   -----------
Less distributions

Dividends
  from
  net
  investment
  income...     (.65)       (.67)    (.68)    (.69)       (.42)       (.60)      (.62)     (.63)     (.64)      (.65)       (.04)

Distributions
  from net
  realized
  gains...      (.13)       (.12)      --       --          --        (.13)      (.12)       --        --        --          --
              ------       ------   ------   ------   -----------   --------   -------   -------   -------   -------   -----------
  Total
  distributions.(.78)       (.79)    (.68)   (.69)        (.42)       (.73)      (.74)     (.63)     (.64)      (.65)       (.04)
              ------       ------   ------   ------   -----------   --------   -------   -------   -------   -------   -----------
Net asset
  value,
  end of
  period...   $11.59      $12.44   $11.88  $11.32      $ 10.80     $ 11.58    $ 12.44   $ 11.87   $ 11.32    $ 10.80     $ 11.58
              ------      ------   ------   ------   -----------   --------   -------   -------   -------    -------   -----------
              ------      ------   ------   ------   -----------   --------   -------   -------   -------    -------   -----------
TOTAL
RETURN#:...     (.59)%     11.79%   11.23%   11.45%       2.01%@     (1.08)%    11.42%    10.68%    11.02%      4.49%       0.10%

RATIOS/SUPPLEMENTAL
  DATA:

Net assets,
  end of
  period
 (000)...     $7,675      $6,622   $2,146   $1,508     $   436     $52,104    $57,286   $51,697   $57,209    $59,216     $   200@@

Average
  net
  assets
 (000)...     $7,141      $3,613   $1,758   $  937     $   260     $55,526    $53,656   $53,477   $58,973   $60,359     $   199@@

Ratios to
  average net
  assets:##

 Expenses,
  including
  distribution
  fees...        .89%        .92%    1.02%    1.02%        .96%*      1.29%      1.32%     1.42%     1.41%     1.30%       1.90%*

Expenses,
excluding
    distribution
    fees...      .79%        .82%     .92%     .92%        .86%*       .79 %      .82%      .92%      .91%      .82%       1.14%*

  Net
  investment
  income...     5.40%       5.58%    5.81%    6.13%       6.36%*      5.40 %     5.18%     5.42%     5.77%     5.99%       6.34%*

Portfolio
turnover...       33%         14%      42%      25%         49%         33 %       14%       42%       25%       49%         33%

 
- ---------------
      * Annualized.
    (D) Commencement of offering of Class A shares.
 (D)(D) Commencement of offering of Class C shares.
      # Total return does not consider the effects of sales loads. Total return
        is calculated assuming a purchase of shares on the first day and a sale
        on the last day of each period reported and includes reinvestment of 
        dividends and distributions. Total returns for periods of less than a 
        full year are not annualized.
     ## Because of the event referred to in (D)(D) and the timing of such, the 
        ratios for the Class C shares are not necessarily comparable to that of
        Class A or B shares and are not necessarily indicative of future ratios.
      @ Restated.
     @@ Figures are actual and not rounded to the nearest thousand.
</TABLE>
 
See Notes to Financial Statements.
                                      -13-
 
<PAGE>
                          INDEPENDENT AUDITORS' REPORT
The Shareholders and Board of Trustees
Prudential Municipal Series Fund, Arizona Series

   We have audited the accompanying statement of assets and liabilities of
Prudential Municipal Series Fund, Arizona Series, including the portfolio of
investments, as of August 31, 1994, the related statements of operations for the
year then ended and of changes in net assets for each of the two years in the
period then ended, and the financial highlights for each of the five years in
the period then ended. These financial statements and financial highlights are
the responsibility of the Fund's management. Our responsibility is to express an
opinion on these financial statements and financial highlights based on our
audits.

   We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements and financial
highlights are free of material misstatement. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements. Our procedures included confirmation of the securities owned as of
August 31, 1994 by correspondence with the custodian. An audit also includes
assessing the accounting principles used and significant estimates made by
management, as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.
   In our opinion, such financial statements and financial highlights present
fairly, in all material respects, the financial position of Prudential Municipal
Series Fund, Arizona Series, as of August 31, 1994, the results of its
operations, the changes in its net assets, and its financial highlights for the
respective stated periods in conformity with generally accepted accounting
principles.

Deloitte & Touche LLP
New York, New York
October 17, 1994


                         FEDERAL INCOME TAX INFORMATION

   We are required by the Internal Revenue Code to advise you within 60 days of
the Series' fiscal year end (August 31, 1994) as to the federal tax status of
dividends paid by the Series during such fiscal year. Accordingly, we are
advising you that in the fiscal year ended August 31, 1994, dividends paid from
net investment income of $.64 per Class A share, $.58 per Class B share, and
$.04 per Class C share were all federally tax-exempt interest dividends. In
addition, the Series paid to both Class A and B shares a long-term capital gain
distribution of $.115 per share which is taxable as such and a short-term
capital gain distribution of $.018 per share which is taxable as ordinary
income.
   In January 1995, you will be advised on IRS Form 1099 DIV or substitute 1099
DIV as to the federal tax status of the distributions received by you in
calendar year 1994.
                                      -14-

<PAGE>
   These graphs are furnished to you in accordance with SEC regulations. They
compare a $10,000 investment in Prudential Municipal Series Fund: Arizona Series
(Class A, Class B, and Class C) with a similar investment in the Lehman Brothers
Municipal Bond Index (the Index) by portraying the initial account values at the
commencement of operations of each class and subsequent account values at the
end of each fiscal year (August 31) beginning in 1990 for Class A, in 1984 for
Class B shares and 1994 for Class C shares. For purposes of the graphs and,
unless otherwise indicated, the accompanying tables, it has been assumed that
(a) the maximum sales charge was deducted from the initial $10,000 investment in
Class A shares; (b) the maximum applicable contingent deferred sales charge was
deducted from the value of the investment in Class B shares and Class C shares,
assuming full redemption on August 31, 1994; (c) all recurring fees (including
management fees) were deducted; and (d) all dividends and distributions were
reinvested. Class B shares will automatically convert to Class A shares on a
quarterly basis approximately seven years after purchase. This conversion
feature is expected to be implemented on or about February 1995 and is not
reflected in the graph. The graph and accompanying tables reflect the past
subsidy and/or waiver of expenses and/or management fees. Without fee waivers
and expense subsidies, the value of a $10,000 investment in the Series and the
Series' average annual total return, as shown above, would have been lower.

   The Index is a weighted index comprised of 21,000 municipal bonds (general
obligation bonds, revenue bonds, insured bonds and prerefunded bonds) selected
by Lehman Brothers as representative of the long-term investment grade municipal
bond market. The Index is an unmanaged index and includes the reinvestment of
all income, but does not reflect the payment of transaction costs and advisory
fees associated with an investment in the Series. The securities which comprise
the Index may differ substantially from the securities in the Series' portfolio
because the Index, among other things, is not state specific. The Lehman
Brothers Municipal Bond Index is not the only index which may be used to
characterize performance of long-term, investment-grade tax-exempt bond funds
and other indexes may portray different comparative performance.
<PAGE>
<PAGE>
Trustees
Edward D. Beach
Eugene C. Dorsey
Delayne Dedrick Gold
Harry A. Jacobs, Jr.
Lawrence C. McQuade
Thomas T. Mooney
Thomas H. O'Brien
Richard A. Redeker
Nancy H. Teeters

Officers
Lawrence C. McQuade, President
Robert F. Gunia, Vice President
Susan C. Cote, Treasurer
S. Jane Rose, Secretary
Ronald Amblard, Assistant Secretary
Deborah A. Docs, Assistant Secretary

Manager
Prudential Mutual Fund Management, Inc.
One Seaport Plaza
New York, NY 10292

Investment Adviser
The Prudential Investment Corporation
Prudential Plaza
Newark, NJ 07101

Distributors
Prudential Mutual Fund Distributors, Inc.
Prudential Securities Incorporated
One Seaport Plaza
New York, NY 10292

Custodian
State Street Bank and Trust Company
One Heritage Drive
North Quincy, MA 02171

Transfer Agent
Prudential Mutual Fund Services, Inc.
P.O. Box 15005
New Brunswick, NJ 08906

Independent Accountants
Deloitte & Touche LLP
1633 Broadway
New York, NY 10019

Legal Counsel
Gardner, Carton & Douglas
Quaker Tower
321 North Clark Street
Chicago, IL 60610-4795

Prudential Mutual Funds
One Seaport Plaza
New York, NY 10292
Toll free (800) 225-1852, Collect (908) 417-7555

This report is not authorized for distribution to prospective 
investors unless preceded or accompanied by a current prospectus.

74435M101   
74435M200                                   MF 117E
74435M598                             Cat. #6426206



























































ANNUAL REPORT               August 31, 1994

Prudential
Municipal
Series Fund

(ICON)

Connecticut
Money Market Series

(LOGO)

<PAGE>

Letter to Shareholders

October 18, 1994

Dear Shareholder:

  Short-term interest rates moved steadily higher during the last 12 months, 
accelerating in 1994 as the Federal Reserve boosted short-term interest rates 
in hopes of preventing inflation from increasing as the economy began to expand
rapidly. As a result, your Prudential Municipal Series Fund Connecticut Money 
Market Series - produced higher yields than six months ago.
<TABLE>

                           SERIES PERFORMANCE
                         As of August 31, 1994
<CAPTION>
Net Asset   Weighted       7-Day       Taxable Equivalent Yield     Net
  Value     Avg. Mat.  Current Yield    @28%   @31%    @39.6%    Asset (Mil.)
<S>         <C>            <C>          <C>    <C>      <C>          <C>
$1.00       77 days        2.22%        3.2%   3.4%     3.9%         $54.3
</TABLE>

  Past performance is no guarantee of future results
  Please note than an investment in the Series is neither insured nor 
guaranteed by the U.S. government, and there can be no assurance that the 
Series will be able to maintain a stable net asset value of $1.00 per share.

  The Connecticut Money Market Series seeks to provide the highest level of 
state and federally tax-exempt current income consistent with the preservation 
of principal and liquidity.  Interest on municipal obligations may be subject 
to the federal alternative minimum tax.  The Series invests primarily in 
high-quality, short-term, tax-exempt obligations issued by the state, 
municipalities, and authorities.  During the year, the Series' credit quality 
remained consistently high, with 90% of its holdings rated in the highest 
category as determined by Moody's Investors Service or Standard & Poor's, or 
if unrated, deemed to be of comparable quality by the adviser.

In 1994, Rates Rose Rapidly

  Short-term taxable interest rates were relatively stable until February, when
the Federal Reserve, concerned that the rapidly expanding economy could ignite 
inflation, started to increase the fed funds rate (the overnight interbank 
lending rate).  If the economy grows too quickly, shortages develop and 
consumers and businesses bid up the prices of materials and labor.

                                  -1-
<PAGE>

The Municipal Market Is Different

  While the fed funds rate spiked 175 basis points (100 basis points is one 
percentage point), the yields of tax-free securities did not rise by a similar 
margin. While this rising interest rate activity in the taxable market does 
affect the tax-free market, the impact generally lags. The short-term municipal
market is also more influenced by seasonal supply and demand factors than 
taxable Treasury bills.

  Rising rates in the taxable market can be followed by higher yields in the 
tax-free market.  Anticipating the Fed would raise interest rates in February, 
we maintained a shorter weighted average maturity so that we could take 
advantage of higher rates as they became available.  Once the Fed moved, we 
selectively extended the maturity of the portfolio.  Generally, our weighted 
average maturity was shorter than that of our peers.

Connecticut's Economy: Restructuring

  Although Connecticut is the wealthiest state in the nation,  its economy has 
been suffering from corporate restructuring.  The state lost 15,000 jobs in the
six months ended April, 1994, 50% more than in the previous six months.  The 
defense industry continues to shrink and insurance companies are shedding 
employees, too.  Connecticut has been hurt nearly as severely as California by 
military cutbacks.

  Although its economy is no longer in decline, there is little evidence of 
significant growth in Connecticut as it continues to restructure.  Most growth 
is centered in Fairfield County, where many residents commute to New York City.
In New London, the naval shipyard has been spared significant cuts, while the 
Indian-operated casino at Ledyard is the most profitable in the nation. Another
gambling bill for Bridgeport will likely be introduced in the next Legislature,
although lawmakers voted it down in the last session. This time, a new governor
will be in office.

  Despite the recession, the state's financial position has improved 
substantially since fiscal 1992, when the personal income tax was adopted and 
the sales tax reduced. The state has restructured its debt and current revenues
are running ahead of schedule. Three consecutive surpluses have pared the 
state's $1.3 billion deficit to $384 million in 1993. The operating  surplus in
1994 was $141 million.

                                      -2-

<PAGE>

The Outlook:  Rates May Rise Again.

  After its August rate increase, the Fed paused to assess its actions.  With 
the Fed ready to move swiftly should price growth inch up above 3%, we believe 
inflation will remain under control. In this environment, we expect short-term 
rates to climb moderately higher, which should have a corresponding effect on 
the Series' yield.

  Once again, it is a pleasure to have you as a shareholder and to report our 
activities to you.

Sincerely,


Lawrence C. McQuade
President


Richard S. Lynes
Portfolio Manager
                                    -3-
<PAGE>


PRUDENTIAL MUNICIPAL SERIES FUND    Portfolio of Investments
CONNECTICUT MONEY MARKET SERIES     August 31, 1994

<TABLE>
<CAPTION>

  Moody's     Principal                                        
   Rating      Amount                                   Value  
(Unaudited)     (000)            Description          (Note 1) 

<C>           <C>          <S>                       <C>
                           SHORT-TERM INVESTMENTS--98.1%
                           Connecticut St. Arpt.
                             Rev.,
                             Bradley Int'l. Airport
                           7.05%, 10/1/94, Ser. 92,
Aaa            $  2,375    F.G.I.C.................  $ 2,384,081
                           Connecticut St. Dev.
                             Auth., Conco Proj.
                           3.00%, 9/1/94, Ser. 85,
P1                1,700    F.R.W.D.................    1,700,000
                           Ctrl. Rev., Lt. & Pwr.
                             Co. Proj.,
                           3.15%, 9/7/94, Ser. 93B,
VMIG1             5,700    F.R.W.D.................    5,700,000
                           Jewish Cmnty. Ctr.
                             of New Haven,
                           2.70%, 9/7/94, Ser. 92,
A-1*                725    F.R.M.D.................      725,000
                           RK Bradley Assoc. Proj.,
                           2.85%, 9/7/94, Ser. 85,
A-2*              1,500    F.R.W.D.................    1,500,000
                           Rand Whitney Container
                             Bd.,
                           2.95%, 9/7/94, Ser. 93,
P1                1,000    F.R.W.D.................    1,000,000
                           SHW Inc. Proj.,
                           3.30%, 9/7/94, Ser. 90,
NR                3,100    F.R.W.D.................    3,100,000
                           Connecticut St., Gen.
                             Oblig.,
Aa                1,000    5.20%, 5/1/95, Ser.
                             94....................    1,012,926
                           Recreation Notes,
                           3.05%, 9/7/94, Ser. 91B,
VMIG1             1,100    F.R.W.D.................    1,100,000
Aa                1,000    5.25%, 12/15/94, Ser.
                             91A...................    1,008,361
                           Connecticut St., Hlth. &
                             Edl. Facs. Auth. Rev.,
                             Charlotte-Hungerford,
                           3.00%, 9/1/94, Ser. B,
VMIG1               900    F.R.W.D.................      900,000
                           Yale Univ., T.E.C.P.,
VMIG1          $  1,400    2.85%, 9/8/94, Ser. L...  $ 1,400,000
VMIG1             1,500    2.85%, 9/8/94, Ser. N...    1,500,000
                           Connecticut St. Hsg.
                             Fin. Auth., Mtg. Fin.
                             Prog. A.N.N.M.T.,
VMIG1             2,000    2.90%, 11/15/94, Ser.
                             93H-2.................    2,000,000
                           Taxable Hsg. Mtg.
                             Fin.Sub.
                           3.65%, 5/15/95,
                             Ser. 92D-2............    1,000,000
VMIG1             1,000
                           Connecticut St Res. Rec.
                             Auth.,
Aaa                 500    8.25%, 11/15/94, Ser.
                             A.....................      504,856
                           Connecticut St. Spec.
                             Assmt., Unemployment
                             Comp.,
                           3.05%, 9/7/94, Ser. 93B,
VMIG1             1,000    F.R.W.D.................    1,000,000
MIG1              1,750    3.10%, 11/15/94, Ser.
                             93A...................    1,752,182
                           Connecticut St. Spec.
                             Tax Oblig., Trans.
                             Infrastructure Rev.,
                           3.20%, 9/7/94, Ser. 90I,
VMIG1             4,100    F.R.W.D.................    4,100,000
                           East Lyme Ct., Gen.
                             Oblig.,
                           4.25%, 8/3/95, Ser. 94,
NR                2,800    B.A.N...................    2,804,951
                           Fairfield Ct., Gen.
                             Oblig., Swr. Assmt.
                             Note
NR                1,750    3.60%, 6/9/95...........    1,751,287
                           Norwich Ct.,
                           3.40%, 9/30/94, Ser. 94,
NR                2,650    B.A.N...................    2,650,826
                           Puerto Rico Comnwlth.,
                             Gov't. Dev. Bank.,
                           2.90%, 9/7/94, Ser. 85,
VMIG1             2,700    F.R.W.D.,...............    2,700,000
                           Puerto Rico Hsg. Fin.
                             Corp. Rev. Med.,
                           2.60%, 9/15/94, Ser.
                             90I,
Aa                2,165    M.T.H.O.T...............    2,165,000
</TABLE>
 
                                  -4-     See Notes to Financial Statements.
 
<PAGE>

PRUDENTIAL MUNICIPAL SERIES FUND
CONNECTICUT MONEY MARKET SERIES

<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                   Value
(Unaudited)     (000)            Description          (Note 1)
<C>           <C>          <S>                       <C>
                           Puerto Rico Ind. Med. &
                             Environ. Facs.,
                             Ana G. Mendez
                             Ed. Fndtn.,
                           2.90%, 9/7/94, Ser. 85,
A-1*           $    200    F.R.W.D.................  $   200,000
                           Reynolds Metal Co.
                             Proj., A.N.N.O.T.,
P1                1,900    4.00%, 9/1/95, Ser. 83
                             A.....................    1,900,000
                           Schering-Plough Corp.,
                           2.80%, 12/1/94, Ser.
                             83A,
AAA*                700    A.N.N.O.T...............      700,000
                           Puerto Rico Maritime
                             Shipping Auth.,
P1                2,000    2.65%, 9/6/94,
                             T.E.C.P...............    2,000,000
                           Stamford Ct.,
MIG1              3,000    3.07%, 3/22/95,
                             B.A.N.................    3,000,632
                                                     -----------
                           Total Investments--98.1%
                           (amortized
                            cost--$53,260,102**)...   53,260,102
                           Other assets in excess
                             of
                             liabilities--1.9%.....    1,042,071
                                                     -----------
                           Net Assets--100%........  $54,302,173
                                                     -----------
                                                     -----------
</TABLE>
- ------------------
(a) The following abbreviations are used in portfolio descriptions:
    A.N.N.M.T.--Annual Mandatory Tender.
    A.N.N.O.T.--Annual Optional Tender.
    B.A.N.--Bond Anticipation Note.
    F.R.M.D.--Floating Rate (Monthly) Demand Note #.
    F.R.W.D.--Floating Rate (Weekly) Demand Note #.
    M.T.H.O.T.--Monthly Optional Tender.
    T.E.C.P.--Tax Exempt Commercial Paper.
   # For purposes of amortized cost valuation, the
     maturity date of Floating Rate Demand Notes is
     considered to be the later of the next date on
     which the security can be redeemed at par, or the
     next date on which the rate of interest is
     adjusted.
   * Standard & Poor's rating.
  ** The cost of securities for federal income tax
     purposes is substantially the same as for financial
     reporting purposes.

NR--Not Rated by Moody's or Standard & Poor's.
The Fund's current Statement of Additional Information contains a description 
of Moody's and Standard & Poor's ratings.
                              -5-     See Notes to Financial Statements.
 
<PAGE>

 PRUDENTIAL MUNICIPAL SERIES FUND
 CONNECTICUT MONEY MARKET SERIES
 Statement of Assets and Liabilities
<TABLE>
<CAPTION>
                                                                                               August 31,
Assets                                                                                            1994
                                                                                              -----------
<S>                                                                                           <C>
Investments, at amortized cost which approximates market value.............................   $53,260,102
Cash.......................................................................................       840,182
Receivable for Fund shares sold............................................................       532,409
Interest receivable........................................................................       405,991
Receivable for investments sold............................................................        75,242
Deferred expenses and other assets.........................................................        29,895
                                                                                              -----------
  Total assets.............................................................................    55,143,821
                                                                                              -----------
Liabilities
Payable for Fund shares reacquired.........................................................       766,555
Accrued expenses and other liabilities.....................................................        38,118
Dividends payable..........................................................................        20,600
Distribution fee payable...................................................................         9,510
Due to Manager.............................................................................         5,855
Deferred Trustees' fees....................................................................         1,010
                                                                                              -----------
  Total liabilities........................................................................       841,648
                                                                                              -----------
Net Assets.................................................................................   $54,302,173
                                                                                              -----------
                                                                                              -----------
Net assets were comprised of:
  Shares of beneficial interest, at $.01 par value.........................................   $   543,022
  Paid-in capital in excess of par.........................................................    53,759,151
                                                                                              -----------
  Net assets, August 31, 1994..............................................................   $54,302,173
                                                                                              -----------
                                                                                              -----------
  Net asset value, offering price and redemption price per share ($54,302,173 / 54,302,173
    shares of beneficial interest issued and outstanding; unlimited number of shares
    authorized)............................................................................         $1.00
                                                                                                    -----
                                                                                                    -----

</TABLE>
 
See Notes to Financial Statements.
                                      -6-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 CONNECTICUT MONEY MARKET SERIES
 Statement of Operations
<TABLE>
<CAPTION>
                                         Year Ended
                                         August 31,
Net Investment Income                       1994
                                         ----------
<S>                                      <C>
Income
  Interest...........................    $1,536,609
                                         ----------
Expenses
  Management fee, net of waiver of
    $243,395.........................        63,440
  Distribution fee...................        75,743
  Custodian's fees and expenses......        60,000
  Transfer agent's fees and
    expenses.........................        35,000
  Reports to shareholders............        28,400
  Legal fees.........................        20,000
  Registration fees..................        13,000
  Amortization of organization
    expense..........................        11,750
  Audit fee..........................        10,000
  Trustees' fees.....................         3,375
  Miscellaneous......................         7,612
                                         ----------
    Total expenses...................       328,320
                                         ----------
Net investment income................     1,208,289
                                         ----------
Realized Loss on Investments
Net realized loss on investment
  transactions.......................        (4,743)
                                         ----------
Net Increase in Net Assets
Resulting from Operations............    $1,203,546
                                         ----------
                                         ----------
</TABLE>
 
 PRUDENTIAL MUNICIPAL SERIES FUND
 CONNECTICUT MONEY MARKET SERIES
 Statement of Changes in Net Assets

<TABLE>
<CAPTION>
                               Year Ended August 31,
Increase (Decrease)        ------------------------------
in Net Assets                  1994             1993
                           -------------   -------------
<S>                        <C>              <C>
Operations
  Net investment
    income...............  $   1,208,289    $   1,150,867
  Net realized gain
    (loss) on investment
    transactions.........         (4,743)             371
                           -------------    -------------
  Net increase in net
    assets resulting from
    operations...........      1,203,546        1,151,238
                           -------------    -------------
Dividends and
  distributions to
  shareholders...........     (1,203,546)      (1,151,238)
                           -------------    -------------
Series share transactions
  (at $1 per share)
  Net proceeds from
    shares
    subscribed...........    210,712,023      197,325,014
  Net asset value of
    shares issued to
    shareholders in
    reinvestment of
    dividends and
    distributions........      1,156,043        1,096,823
  Cost of shares
    reacquired...........   (215,359,425)    (181,107,990)
                           -------------    -------------
  Net increase (decrease)
    in net assets from
    Series share
    transactions.........     (3,491,359)      17,313,847
                           -------------    -------------
Total increase
  (decrease).............     (3,491,359)      17,313,847
Net Assets
Beginning of year........     57,793,532       40,479,685
                           -------------    -------------
End of year..............  $  54,302,173    $  57,793,532
                           -------------    -------------
                           -------------    -------------
</TABLE>
 
See Notes to Financial Statements.        See Notes to Financial Statements.
                                      -7-
 <PAGE>
<PAGE>

 PRUDENTIAL MUNICIPAL SERIES FUND
 CONNECTICUT MONEY MARKET SERIES

 Notes to Financial Statements
   Prudential Municipal Series Fund (the ``Fund'') is registered under the
Investment Company Act of 1940, as an open-end investment company. The Fund was
organized as a Massachusetts business trust on May 18, 1984 and consists of
seventeen series. The monies of each series are invested in separate,
independently managed portfolios. The Connecticut Money Market Series (the
``Series'') commenced investment operations on August 5, 1991. The Series is
non-diversified and seeks to provide the highest level of income that is exempt
from Connecticut State, local and federal income taxes with the minimum of risk
by investing in ``investment grade'' tax-exempt securities having a maturity of
thirteen months or less and whose ratings are within the two highest ratings
categories by a nationally recognized statistical rating organization, or if not
rated, are of comparable quality. The ability of the issuers of the securities
held by the Series to meet their obligations may be affected by economic
developments in a specific state, industry or region.
                              
Note 1. Accounting            The following is a summary
Policies                      of significant accounting poli-
                              cies followed by the Fund, and the Series, in the
preparation of its financial statements.
Securities Valuations: Portfolio securities of the Series are valued at
amortized cost, which approximates market value. The amortized cost method of
valuation involves valuing a security at its cost on the date of purchase and
thereafter assuming a constant amortization to maturity of any discount or
premium.
   All securities are valued as of 4:30 p.m., New York time.
Securities Transactions and Investment Income: Securities transactions are
recorded on the trade date. Realized gains and losses on sales of investments
are calculated on the identified cost basis. Interest income is recorded on the
accrual basis.
Federal Income Taxes: For federal income tax purposes, each series in the Fund
is treated as a separate taxpaying entity. It is the intent of the Series to
continue to meet the requirements of the Internal Revenue Code applicable to
regulated investment companies and to distribute all of its net income to
shareholders. For this reason and because substantially all of the Series' 
gross income consists of tax-exempt interest, no federal income tax provision 
is required.
Dividends: The Series declares daily dividends from net investment income.
Payment of dividends is made monthly. Income distributions and capital gain
distributions are determined in accordance with income tax regulations which 
may differ from generally accepted accounting principles.
Deferred Organization Expenses: The Series incurred approximately $52,600 in
organization and initial registration expenses. Such amount has been deferred
and is being amortized over a period of 60 months ending July 1996.
                              
Note 2. Agreements            The Fund has a management
                              agreement with Prudential Mutual Fund Management,
Inc. (``PMF''). Pursuant to this agreement, PMF has responsibility for all
investment advisory services and supervises the subadviser's performance of such
services. PMF has entered into a subadvisory agreement with The Prudential
Investment Corporation (``PIC''); PIC furnishes investment advisory services in
connection with the management of the Fund. PMF pays for the cost of the
subadviser's services, the compensation of officers of the Fund, occupancy and
certain clerical and bookkeeping costs of the Fund. The Fund bears all other
costs and expenses.
   The management fee paid PMF is computed daily and payable monthly, at an
annual rate of .50 of 1% of the average daily net assets of the Series. PMF
waived its entire management fee until October 31, 1993. Effective November 1,
1993, PMF reduced the management fee waiver to 75%. The amount of fees waived
for the fiscal year ended August 31, 1994 amounted to $243,395 ($.004 per share;
.40% of average net assets).
   The Fund has a distribution agreement with Prudential Mutual Fund
Distributors, Inc. (``PMFD''). To reimburse PMFD for its expenses incurred
pursuant to a plan of distribution, the Fund pays PMFD a reimbursement, accrued
daily and payable monthly, at an annual rate of .125 of 1% of the Series'
average daily net assets. PMFD pays various broker-dealers, including Prudential
Securities Incorporated (``PSI'') and Pruco Securities Corporation, affiliated
broker-dealers, for account servicing fees and other expenses incurred by such
broker-dealers.
   PMFD is a wholly-owned subsidiary of PMF; PSI, PMF and PIC are (indirect)
wholly-owned subsidiaries of The Prudential Insurance Company of America.
                                      -8-
 <PAGE>
<PAGE>
                              
Note 3. Other                 Prudential Mutual Fund Ser-
Transactions                  vices, Inc. (``PMFS''), a 
with Affiliates               wholly-owned subsidary of 
                              PMF, serves as the Fund's transfer agent. During
the year ended August 31, 1994, the Series incurred fees of approximately
$29,000 for the services of PMFS. As of August 31, 1994, approximately $2,700 of
such fees were due to PMFS. Transfer agent fees and expenses in the Statement of
Operations also include certain out-of-pocket expenses paid to non-affiliates.
                                      -9-
 <PAGE>
<PAGE>

 PRUDENTIAL MUNICIPAL SERIES FUND
 CONNECTICUT MONEY MARKET SERIES
 Financial Highlights

<TABLE>
<CAPTION>
                                                                                                                August 5,
                                                                                                                  1991*
                                                                              Year ended August 31,              through
                                                                       ------------------------------------     August 31,
                                                                           1994          1993        1992          1991
<S>                                                                    <C>              <C>         <C>         <C>
                                                                       ------------     -------     -------     ----------
PER SHARE OPERATING PERFORMANCE:
Net asset value, beginning of period...............................      $   1.00       $  1.00     $  1.00      $    1.00
Net investment income and realized gains(D)........................          .020          .022        .034           .003
Dividends and distributions to shareholders........................         (.020)        (.022)      (.034)         (.003)
                                                                       ------------     -------     -------     ----------
Net asset value, end of period.....................................      $   1.00       $  1.00     $  1.00      $    1.00
                                                                       ------------     -------     -------     ----------
                                                                       ------------     -------     -------     ----------
TOTAL RETURN#:.....................................................          2.02%         2.20%       3.42%           .30%
RATIOS/SUPPLEMENTAL DATA:
Net assets, end of period (000)....................................      $ 54,302       $57,794     $40,480      $  10,904
Average net assets (000)...........................................      $ 60,594       $53,152     $33,964      $   6,730
Ratios to average net assets(D):
  Expenses, including distribution fee.............................          .542%         .387%       .125%          .125%**
  Expenses, excluding distribution fee.............................          .417%         .262%        .00%           .00%**
  Net investment income............................................          1.99%         2.17%       3.20%          4.42%**
</TABLE>
 
- ---------------
  * Commencement of investment operations.
 ** Annualized.
(D) Net of management fee waiver and/or expense subsidy.
  # Total returns for periods of less than a full year are not annualized.
 
See Notes to Financial Statements.
                                      -10-
 <PAGE>
<PAGE>
                          INDEPENDENT AUDITORS' REPORT

The Shareholders and Board of Trustees
Prudential Municipal Series Fund, Connecticut Money Market Series
   We have audited the accompanying statement of assets and liabilities of
Prudential Municipal Series Fund, Connecticut Money Market Series, including the
portfolio of investments, as of August 31, 1994, the related statements of
operations for the year then ended and of changes in net assets for each of the
two years in the period then ended, and the financial highlights for each of the
three years in the period then ended and for the period August 5, 1991
(commencement of investment operations) through August 31, 1991. These financial
statements and financial highlights are the responsibility of the Fund's
management. Our responsibility is to express an opinion on these financial
statements and financial highlights based on our audits.
   We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements and financial
highlights are free of material misstatment. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements. Our procedures included confirmation of the securities owned as of
August 31, 1994 by correspondence with the custodian. An audit also includes
assessing the accounting principles used and significant estimates made by
management, as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.
   In our opinion, such financial statements and financial highlights present
fairly, in all material respects, the financial position of Prudential Municipal
Series Fund, Connecticut Money Market Series, as of August 31, 1994, the results
of its operations, the changes in net assets, and its financial highlights for
the respective stated periods in conformity with generally accepted accounting
principles.

Deloitte & Touche LLP
New York, New York
October 17, 1994

                         FEDERAL INCOME TAX INFORMATION

   We are required by the Internal Revenue Code to advise you within 60 days of
the Series' fiscal year end (August 31, 1994) as to the federal tax status of
dividends paid by the Series during such fiscal year. Accordingly, we are
advising you that in the fiscal year ended August 31, 1994, dividends paid from
net investment income of .020 per share were all federally tax-exempt interest
dividends.
                                      -11-
 <PAGE>
<PAGE>


Trustees
Edward D. Beach
Eugene C. Dorsey
Delayne Dedrick Gold
Harry A. Jacobs, Jr.
Lawrence C. McQuade
Thomas T. Mooney
Thomas H. O'Brien
Richard A. Redeker
Nancy Hays Teeters

Officers
Lawrence C. McQuade, President
Robert F. Gunia, Vice President
Susan C. Cote, Treasurer
S. Jane Rose, Secretary
Ronald Amblard, Assistant Secretary
Deborah A. Docs, Assistant Secretary

Manager
Prudential Mutual Fund Management, Inc.
One Seaport Plaza
New York, NY 10292

Investment Adviser
The Prudential Investment Corporation
Prudential Plaza
Newark, NJ 07101

Distributor
Prudential Mutual Fund Distributors, Inc.
One Seaport Plaza
New York, NY 10292

Custodian
State Street Bank and Trust Company
One Heritage Drive
North Quincy, MA 02171

Transfer Agent
Prudential Mutual Fund Services, Inc.
P.O. Box 15005
New Brunswick, NJ 08906

Independent Accountants
Deloitte & Touche LLP
1633 Broadway
New York, NY 10019

Legal Counsel
Gardner, Carton & Douglas
Quaker Tower
321 North Clark Street
Chicago, IL 60610-4795

Prudential Mutual Funds
One Seaport Plaza
New York, NY 10292
Toll free (800) 225-1852, Collect (908) 417-7555

This report is not authorized for distribution to prospective investors 
unless preceded or accompanied by a current prospectus.

                                     MF 154E
74435M648         (LOGO)       Cat. #4445050



























































ANNUAL REPORT                            August 31, 1994

Prudential
Municipal
Series Fund

(ICON)

Florida Series 

(LOGO)

<PAGE>

Letter to Shareholders

October 18, 1994

Dear Shareholder:

   It has been a most difficult year in the U.S. financial markets.  When we
last wrote in February interest rates were starting to rise, ending a
three-year long bull market in bonds. What started as a trickle has become a
torrent. Interest rates have continued to increase this year, sending bond 
prices down sharply.  Of course, as interest rates rise, bond prices decline.
In this environment of falling prices and unusual volatility, your Prudential
Municipal Series Fund -- Florida Series sought to minimize risk while
maximizing your tax-free income.

   The Series seeks maximum income exempt from federal income taxes* consistent
with preservation of capital. The Series invests in investment grade bonds.
The Series performed in line with the Lipper Florida Municipal Debt Average
over the last year, but because long-term interest rates rose, total returns
were disappointing. As a result, the Series has become more cautious and
shortened its average maturity.

<TABLE>

                           SERIES PERFORMANCE
                          As of August 31, 1994
<CAPTION>
                             30-day          Taxable Equivalent Yields
                NAV         SEC Yield          @28%   @31%    @39.6%

<S>            <C>          <C>               <C>     <C>     <C>

Class A        $9.91          5.7%             7.9%    8.3%    9.5%
Class B        $9.91          N/A               N/A     N/A     N/A
Class C        $9.91          5.2%             7.3%    7.6%    8.7%
</TABLE>

   Investment return and principal value will fluctuate so that an investor's
shares, when redeemed, may be worth more or less than their original cost.
Past performance is no guarantee of future results.

   *Interest on municipal obligations may be subject to the federal 
alternative minimum tax.  See your Series' prospectus for more details.

                                  -1-

<PAGE>
<TABLE>
                                    TOTAL RETURNS
<CAPTION>

                Historical  (As of 8/31/94)1    Average Annual (As of 9/30/94)2

                   1-Yr.     5-Yr.  Since Incep.**  1-Yr.  5-Yr.  Since Incep.**

<S>              <C>       <C>       <C>          <C>     <C>     <C>

Class A            -1.7%      N/A     +34.3%       -7.7%   N/A      +6.6%

Class B             N/A       N/A      -0.1%        N/A    N/A       N/A

Class C            -2.4%      N/A      +0.7%       -6.5%   N/A      -1.2%

Lipper FL

Muni Debt Avg.***  -2.1%     +48.1%   +81.9%

</TABLE>

   1 Source: Lipper Analytical Services, Inc. These figures do not take into
account sales charges.

   2 Source: Prudential Mutual Fund Management, Inc.  These averages take into
account applicable sales charges.  The Series charges a maximum initial sales
charge of 3% for Class A shares.  Class B shares are subject to a declining
contingent deferred sales charge of 5%, 4%, 3%, 2%, 1% and 1%, respectively,
for the first six years.  Class B shares will automatically convert to Class A
shares approximately seven years after purchase. This conversion feature is
expected to be implemented in February 1995.  Class C shares are sold subject
to a contingent deferred sales charge of 1% during the first year.

    **Inception on January 22, 1990 for Class A, and August 1, 1994 for Class B
and July 26, 1993 for Class C.

   ***These are the average returns of 57 Florida municipal debt funds for
one-year, five-year, and since inception of Class A shares, as determined by
Lipper Analytical Services, Inc.

Once Was Not Enough

   When we wrote to you in February, the Federal Reserve raised short-term
interest rates for the first time in years, hoping to control inflation. Since
then, the Fed has moved four more times, until the federal funds rate (the
overnight interbank lending rate) now stands at 4.75%, up from 3% at the start
of the year.  The Fed also increased the discount rate (at which it lends banks
money) to 4% from 3% over the same period.

   Interest rates rise when the financial markets fear inflation, the bond
holder's enemy. Inflation is feared because it robs purchasing power from a
bond's fixed-interest rate.

   Municipal bond interest rates increased by nearly a percentage point, to
6.46% on August 25 from 5.52% on December 29, 1993, as measured by the Bond
Buyer's Revenue Bond Index, a widely used yardstick of interest rates in the
tax-free market.

Florida: Growing Rapidly

   Florida's economic growth is among the strongest in the nation, largely as 
a result of its growing tourism, trade, agriculture and financial industries.
Construction this year could reach a five-year high, easily leading the
nation.

   Still, there are some concerns with the state.  Its financial position is
highly vulnerable to economic fluctuations because 70% of its general fund
revenues are derived from sales taxes. In an improving economy, these revenues

                                  -2-

<PAGE>
have been exceeding projections.  But the state has a large proportion of
elderly residents on fixed incomes, who comprise an even larger portion of
voters, so it is very difficult to increase property taxes. At the same time,
the government will need to provide in the next five years for a school
enrollment climbing 18% and the state will also need an additional 30,000
prison beds.

   One particular strain in recent months has been the Cuban refugee situation.
Over the summer, President Clinton declined Governor Chiles' request for
assistance. Depending on developments, the state could be faced with additional
financial and economic burdens unless it gets direct federal assistance.

A Tax Reminder

   As a result of the federal Revenue Reconciliation Act of 1993, which affects
bonds purchased after April 30, 1993, it is possible that this year you may
have some taxable income from your tax-free municipal bond fund. The law
stipulates that the portion of any gain realized on the sale or retirement of a
tax-free bond purchased at a market discount to its face value must be taxed as
ordinary income.

   As a result of this change in federal tax law, some discount bonds have been
selling at levels so cheap they will produce a higher after-tax return than
other bonds not subject to the provisions of the new law. We have occasionally
taken advantage of this market imbalance because we have determined that at
very low prices these bonds can still provide you with a higher after-tax
return on your investment.

The Outlook

   We expect volatility in the municipal bond market until the economy reaches
a level of growth that is sustainable without causing inflation.  If the
economy continues to surge, the ever vigilant Fed will move once again,
boosting short-term rates. If the economy slows substantially, long term rates
should stabilize. Although rates may keep rising, we believe that most of the
increase is now behind us.

   In the months ahead, we expect supply - or the lack of it - to become more
important in the tax-free municipal bond market. Through the first eight months
of the year, new issue volume is off 42%, according to Securities Data Co.,
which tracks this statistic. The pace is accelerating. In August, new issue
volume fell 56%.

                                  -3-

<PAGE>
   As always, it is a pleasure to have you as a shareholder in the Prudential
Municipal Series Fund -- Florida Series, and to take this opportunity to 
report our activities to you.

Sincerely,
Lawrence C. McQuade
President

Marie Conti
Portfolio Manager

                                  -4-

<PAGE>

PRUDENTIAL MUNICIPAL SERIES FUND      Portfolio of Investments
FLORIDA SERIES                                 August 31, 1994
<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                  Value
(Unaudited)     (000)             Description         (Note 1)

<C>           <C>            <S>                    <C>
                             LONG-TERM INVESTMENTS--97.8%
                             Alachua Cnty. Hlth. Facs. Auth.
                               Rev., Santa Fe Healthcare
                               Facs. Proj.,
Baa            $  1,750      7.60%, 11/15/13......  $  1,815,520
                             Alachua Cnty. Ind. Dev. Rev.,
                               HB Fuller Co. Proj.,
NR                3,000      7.75%, 11/1/16.......     3,152,910
                             Brevard Cnty. Edl. Facs. Auth.,
                               Florida Inst. of Techn.,
BBB+*             1,500      6.875%, 11/1/22......     1,533,345
                             Wuesthoff Mem. Hosp.,
                             6.625%, 4/1/13, Ser.
Aaa               1,000        A, M.B.I.A.........     1,041,280
                             Broward Cnty. Edl. Facs. Auth.
                               Rev., Nova Univ. Dorm. Proj.,
                             7.50%, 4/1/17, Ser.
BBB*              1,500(D)     A..................     1,717,890
                             Broward Cnty. Res. Rec. Rev.,
                               Ltd. Partnership So. Proj.,
A                 2,730      7.95%, 12/1/08.......     2,993,882
                             Broward Cnty., Wtr. & Swr. Rev.,
                             5.125%, 10/1/15,
Aaa               1,750        A.M.B.A.C..........     1,530,200
                             Citrus Cnty. Poll.
                               Ctrl. Rev.,
                               Pwr. Crystal Proj.,
                             6.35%, 2/1/22, Ser.
Aaa               2,300        B, M.B.I.A.........     2,325,093
                             City of Atlantis,
                               Wtr. & Swr. Rev.,
BBB*              1,750      6.50%, 9/1/22........     1,732,167
                             City of Cocoa,
                               Wtr. & Swr. Rev.,
                             5.125%, 10/1/13,
                               Ser. B,
Aaa               1,000        A.M.B.A.C..........       888,300
                             City of Deerfield
                               Beach,
                               Wtr. & Swr. Rev.,
                             6.125%, 10/1/06,
Aaa                 550        F.G.I.C............       575,559
                             Clay Cnty. Hsg. Fin. Auth. Rev.,
                               Sngl. Fam. Mtge.,
                             7.45%, 9/1/23, Ser.
Aaa            $    375        A, G.N.M.A.........  $    386,396
                             Clay Cnty. Utils.
                               Sys. Rev.,
                             5.00%, 11/1/23,
Aaa               3,500        F.G.I.C............     2,915,955
                             Coral Springs Impvt.
                               Dist., Wtr. & Swr.
                               Rev.,
                             6.00%, 6/1/10,
Aaa               1,000        M.B.I.A............     1,012,610
                             Dade Cnty. Hlth.
                               Facs. Auth.
                               Rev., Baptist Hosp.
                               of
                               Miami Proj.,
                             6.75%, 5/1/08, Ser.
Aaa                 500        A, M.B.I.A.........       544,345
                             No. Shore Med. Ctr. Proj.,
Aaa                 750        6.50%, 8/15/15, A.M.B.A.C.775,493
                             Dade Cnty. Hsg. Fin. Auth. Rev.,
                               Sngl. Fam. Mtge. G.N.M.A.,
                             7.75%, 9/1/22, Ser.
Aaa                 980        C..................     1,024,443
                             7.25%, 9/1/23, Ser.
Aaa                 360(D)(D)   B..................      367,999
                             Dade Cnty. Pub. Facs. Rev.,
                               Jackson Mem. Hosp. M.B.I.A.,
                             4.875%, 6/1/15, Ser.
Aaa               2,000        A..................     1,676,380
Aaa               2,000      5.25%, 6/1/23........     1,731,940
                             Dade Cnty. Pub. Impvt. Rev.,
                               J & K Seaport,
                               6.50%, 10/1/26,
Aaa               5,500        A.M.B.A.C.    5,666,705
                             Dade Cnty. Sch. Brd. Ctfs. of
                               Part.,
                             6.00%, 5/1/14, Ser.
Aaa               2,725        A, M.B.I.A.........     2,686,087
                             Dade Cnty. Sch. Dist., M.B.I.A.,
Aaa               1,235      5.00%, 8/1/11........     1,093,988
Aaa               1,500      5.00%, 8/1/13........     1,314,675
                             5.00%, 8/1/14, Ser.
Aaa               2,000        1994...............     1,727,520
                             Dade Cnty. Wtr. & Swr. Sys. Rev.,
                             5.00%, 10/1/13,
Aaa               4,500        F.G.I.C............     3,927,645
</TABLE>
 
                                      -5-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND
FLORIDA SERIES
<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                  Value
(Unaudited)     (000)             Description         (Note 1)

<C>           <C>            <S>                    <C>
                             Duval Cnty. Hsg. Fin. Auth. Rev.,
                               Sngl. Fam. Mtge.,
                             8.375%, 12/1/14,
AAA*           $    685        G.N.M.A............  $    704,139
                             Enterprise Cmnty. Dev. Dist.,
                               Osceola Co., Spl. Assmnt.,
                             6.00%, 5/1/10,
Aaa               2,320        M.B.I.A............     2,330,626
                             Escambia Cnty. Hlth. Facs. Auth.
                               Rev., Baptist Hosp. Inc.,
                             8.70%, 10/1/14, Ser.
BBB+*             1,830        A..................     2,033,789
                             Escambia Cnty. Hsg. Fin. Auth.
                               Rev., Sngl. Fam. Mtge.,
                             7.40%, 10/1/23, Ser.
Aaa                 845(D)(D)   A, G.N.M.A.........      878,040
                             Escambia Cnty. Poll. Ctrl., Rev.,
                               Champion Int'l. Corp. Proj.,
Baa1              1,500      6.90%, 8/1/22........     1,499,850
                             Florida St. Brd. of
                               Ed.
                               Cap. Outlay, Pub.
                               Ed.,
Aa                1,400      5.125%, 6/1/18.......     1,207,808
                             7.25%, 6/1/23, Ser.
Aaa                 255(D)     A..................       287,586
                             7.25%, 6/1/23, Ser.
Aa                  245        A..................       269,828
                             Florida St. Broward Cnty.,
                               Expwy. Auth.,
Aa                2,100@     9.875%, 7/1/09.......     2,873,808
                             Florida St. Dept. of
                               Trans.,
                             7.20%, 7/1/11, Ser.
Aaa               1,000(D)/(D)(D) A, A.M.B.A.C.....    1,134,580
                             Florida St. Div. Bond Fin. Dept.,
                               Gen. Svcs. Rev.,
                             6.75%, 7/1/13,
Aaa               1,500        A.M.B.A.C..........     1,583,445
                             Gen. Svcs. Rev., Dept. of
                               Natural Res. Preservation,
                             6.25%, 7/1/09, Ser.
Aaa               1,650        A, M.B.I.A.........     1,689,122
                             Florida St. Gen.
                               Oblig., Ref. Dade
                               Cnty. Rd.,
Aa                1,500      5.125%, 7/1/13.......     1,345,155
                             Florida St. Mun. Pwr. Agcy. Rev.,
                               4.50%, 10/1/27,
Aaa            $  4,365        A.M.B.A.C.   $3,263,405
                             Gainesville Gtd. Entitlement Rev.,
                             5.50%, 8/1/10,
Aaa               2,635        A.M.B.A.C..........     2,524,383
                             Hillsborough Cnty.
                               Ind. Dev.
                               Rev., Univ. Cmnty.
                               Hosp. Proj.,
                             5.75%, 8/15/10,
Aaa               1,000        M.B.I.A............       980,540
                             Hillsborough Cnty.
                               Solid
                               Waste & Res. Rec.,
                             5.70%, 10/1/08,
Aaa               2,000        M.B.I.A............     1,973,240
                             Jacksonville Cap. Impvt. Rev.,
                               Gator Bowl Proj.,
                               6.00%, 10/1/25,
Aaa               1,625        A.M.B.A.C.    1,593,491
                             Jacksonville Elec. Auth. Rev.,
                               Bulk Pwr. Supply Scherer,
Aaa               1,000(D)/(D)(D) 6.75%, 10/1/21...    1,104,090
                             Elec. Sys. 3-B,
Aa1               1,000      5.20%, 10/1/13.......       895,110
                             St. Johns Rvr. Pwr.
                               Park,
                             Zero Coupon,
Aa1               3,000        10/1/10............     1,153,860
                             St. Johns Rvr.,
                             5.40%, 10/1/10, Ser.
Aa1               1,000        8..................       934,660
                             Jacksonville Excise Tax Rev.,
                               6.25%, 10/1/05,
Aaa               1,000        A.M.B.A.C.    1,058,970
                             Jacksonville Hlth. Facs. Auth.
                               Hosp. Rev.,
                               Baptist Med. Ctr. Proj.,
                             7.30%, 6/1/19, Ser.
Aaa                 450        A, M.B.I.A.........       492,133
                             Daughters Of Charity,
                             5.00%, 11/15/15, Ser.
Aa                1,000        A..................       841,210
                             Nat'l. Ben. Assoc.,
Baa1              1,825      7.00%, 12/1/22.......     1,840,622
                             St. Lukes Hosp. Assoc. Proj.,
AA+*              1,000      7.125%, 11/15/20.....     1,062,570
</TABLE>
 
                                      -6-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND
FLORIDA SERIES
<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                  Value
(Unaudited)     (000)             Description         (Note 1)

<C>           <C>            <S>                    <C>
                             Jacksonville Wtr. & Swr. Dev.
                               Rev., Suburban Utils.,
A2             $  1,000      6.75%, 6/1/22........  $  1,063,730
                             Kissimmee Util. Auth.
                               Elec.
                               Sys. Rev.,
                               F.G.I.C.,
Aaa               2,500      5.375%, 10/1/12......     2,315,850
                             5.30%, 10/1/17, Ser.
Aaa               2,000        A..................     1,780,480
                             Lake Cnty. Res. Rec.
                               Ind. Dev. Rev.,
                             5.95%, 10/1/13, Ser.
Baa               1,035        A..................       943,703
                             Lee Cnty. Trans. Facs. Rev.,
                               6.75%, 10/1/11,
Aaa               1,000        A.M.B.A.C.    1,057,590
                             Leon Cnty. Hsg. Fin. Auth. Rev.,
                               Sngl. Fam. Mtge.,
                             7.30%, 4/1/21, Ser.
Aaa                 485        A, G.N.M.A.........       499,574
                             Martin Cnty.,
                             4.50%, 2/1/09,
Aaa               1,575        A.M.B.A.C..........     1,339,569
                             Miami Hlth. Facs. Auth. Hosp.
                               Rev., Mercy Hosp.,
A                 1,000      8.125%, 8/1/11.......     1,097,440
                             North Port Util.
                               Rev.,
                             6.25%, 10/1/17,
Aaa               2,500        F.G.I.C............     2,522,150
                             Okaloosa Cnty. Cap. Impvt. Rev.,
                             Zero Coupon, 12/1/06,
Aaa                 450        M.B.I.A............       229,298
                             Orange Cnty. Hsg.
                               Fin. Auth.,
                               Mtge. Rev.,
                             7.375%, 9/1/24, Ser.
AAA*                420        A, G.N.M.A.........       431,382
                             MultiFam. Ashley Point Apts.,
BBB+*             1,200      6.85%, 10/1/16.......     1,175,856
BBB+*               855      7.10%, 10/1/24.......       852,281
                             Orlando & Orange Cnty. Expwy.
                               Auth. Rev.,
Aaa               1,000(D)/(D)(D) 7.125%, 7/1/06...    1,066,230
                             5.25%, 7/1/14,
Aaa               1,000        A.M.B.A.C..........       895,460
Aaa               1,000(D)/(D)(D) 7.25%, 7/1/14....    1,069,320
                             Orlando Utils. Comn.,
                               Wtr. & Elec. Rev.,
Aa1            $  1,500      5.125%, 10/1/19......  $  1,284,195
Aa1               2,515      5.00%, 10/1/23.......     2,072,662
                             Palm Beach Cnty. Arpt. Sys. Rev.,
                             7.75%, 10/1/10,
Aaa               1,000        M.B.I.A............     1,138,370
                             Polk Cnty. Sch. Brd.,
                               Ctfs. of Part.,
                             4.875%, 1/1/18,
Aaa               1,000        F.S.A..............       824,790
                             Puerto Rico Gen.
                               Oblig.,
                             8.393%, 7/1/20,
Aaa               3,000**      F.S.A..............     2,812,500
                             Puerto Rico Elec. Pwr. Auth. Rev.,
Baa1              1,000      6.20%, 7/1/04........     1,061,000
                             Puerto Rico Hsg. Fin. Corp. Rev.,
                               Sngl. Fam. Mtge. Rev.,
Baa               2,000      5.125%, 12/1/05......     1,875,240
Baa               1,000      5.25%, 12/1/06.......       934,660
                             Puerto Rico Hwy. Auth. Rev.,
Baa1              2,000      5.00%, 7/1/02........     1,955,520
Baa1              2,000      5.50%, 7/1/19........     1,795,620
                             5.25%, 7/1/20, Ser
Baa               1,250        W..................     1,077,812
                             7.75%, 7/1/16, Ser.
Baa1                500(D)     Q..................       579,585
                             Puerto Rico Pub. Bldgs. Auth.,
                               Pub. Ed. & Hlth. Facs.,
                             7.875%, 7/1/16, Ser.
Aaa               1,000(D)/**   H..................    1,106,940
                             Puerto Rico Tel. Auth. Rev.,
                             7.381%, 1/16/15, Ser. I,
Aaa               2,250        M.B.I.A............     1,954,687
                             Reedy Creek Impvt. Dist. Utils.
                               Rev., M.B.I.A.,
                             5.00%, 10/1/19, Ser.
Aaa               2,500        1..................     2,109,400
                             Sanford Wtr. & Swr. Rev.,
                               4.50%, 10/1/21,
Aaa               3,955        A.M.B.A.C.    3,035,383
</TABLE>
 
                                      -7-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND
FLORIDA SERIES
<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                  Value
(Unaudited)     (000)             Description         (Note 1)

<C>           <C>            <S>                    <C>
                             St. Petersburg Hlth. Facs. Auth.
                               Rev., Allegheny Hlth. Prog.,
                             7.00%, 12/1/15,
Aaa            $  1,000        M.B.I.A............  $  1,080,200
                             Tampa Allegheny Hlth.
                               Sys.
                               Rev., St. Joseph
                               Hosp.,
                             6.70%, 12/1/07,
Aaa               2,535        M.B.I.A............     2,736,127
                             Tampa Gtd. Entitlement Rev.,
                               7.05%, 10/1/07,
Aaa               2,000        A.M.B.A.C.    2,191,480
                             Venice Cap. Impvt.
                               Rev.,
                               Venice Hosp. Proj.,
A                 2,000      5.75%, 12/1/24.......     1,764,140
                             Vero Beach Wtr. & Swr. Rev.,
                             5.00%, 12/1/21,
Aaa               2,245        F.G.I.C............     1,879,671
                             Virgin Islands Pub. Fin. Auth.
                               Rev.,
                               Hwy. Trans. Trust Fund,
BBB*                260      7.65%, 10/1/99.......       273,546
                             Ref. Matching Loan
                               Notes,
                             7.25%, 10/1/18, Ser.
NR                  900        A..................       928,458
                             Virgin Islands
                               Territory, Hugo
                               Ins. Claims Fund
                               Proj.,
                             7.75%, 10/1/06, Ser.
NR                1,405        91.................     1,536,269
                             Volusia Cnty. Edl.
                               Fac.
                               Auth. Rev.,
AAA*              1,000      6.625%, 10/15/22.....     1,029,980
                             Volusia Cnty. Hlth.
                               Facs. Auth. Rev.,
BBB+*             2,000(D)   8.25%, 6/1/20........     2,349,020
                                                    ------------
                             Total long-term
                               investments
                               (cost
                               $144,835,817)......   143,441,555
                                                    ------------
                             SHORT-TERM INVESTMENTS--0.6%
                             Palm Beach Cnty. Wtr. & Swr. Rev.,
                             3.25%, 9/1/94,
VMIG1          $    700        F.R.D.D............  $    700,000
                             Pinellas Cnty. Hlth. Facs. Auth.
                               Rev.,
                               Pooled Hosp. Loan Prog.,
                             3.25%, 9/1/94,
VMIG1               200        F.R.D.D............       200,000
                                                    ------------
                             Total short-term
                               investments
                               (cost $900,000)....       900,000
                                                    ------------
                             Total Investments--98.4%
                             (cost $145,735,817; Note
                               5)                    144,341,555
                             Other assets in
                               excess of
                              liabilities--1.6%...     2,273,823
                                                    ------------
                             Net Assets--100%.....  $146,615,378
                                                    ------------
                                                    ------------
</TABLE>
 
- ---------------

 (a) The following abbreviations are used in portfolio
     descriptions:
     A.M.B.A.C.--American Municipal Bond Assurance
     Corporation.
       F.G.I.C.--Financial Guaranty Insurance Company.
       F.R.D.D.--Floating Rate (Daily) Demand Note.#
       F.S.A.--Financial Security Assurance.
       G.N.M.A.--Government National Mortgage
       Association.
       M.B.I.A.--Municipal Bond Insurance Association.
   # For purposes of amortized cost valuation, the
     maturity date of Floating Rate Demand Notes is
     considered to be the later of the next date on
     which the security can be redeemed at par or the
     next date on which the rate of interest is
     adjusted.
 (D) Prerefunded issues are secured by escrowed cash
     and/or direct U.S. guaranteed obligations.
 (D)(D) Indicates a when-issued security.
   @ Pledged as initial margin on financial futures
     contracts.
   * Standard & Poor's rating.
  ** Inverse floating rate bond. The coupon is
     inversely indexed to a floating interest rate. The
     rate shown is the rate at period end.
N.R.--Not Rated by Moody's or Standard & Poor's.

The Fund's current Statement of Additional Information contains a description of
Moody's and Standard & Poor's ratings.
                                      -8-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 FLORIDA SERIES
 Statement of Assets and Liabilities
<TABLE>
<CAPTION>
Assets                                                                                     August 31, 1994
                                                                                           ---------------
<S>                                                                                        <C>
Investments, at value (cost $145,735,817)...............................................    $ 144,341,555
Cash....................................................................................           29,767
Interest receivable.....................................................................        2,556,815
Receivable for investments sold.........................................................        2,028,494
Receivable for Fund shares sold.........................................................          485,625
Due from Manager........................................................................           78,650
Prepaid expenses and other assets.......................................................           12,863
                                                                                           ---------------
  Total assets..........................................................................      149,533,769
                                                                                           ---------------
Liabilities
Payable for investments purchased.......................................................        1,486,125
Payable for Fund shares reacquired......................................................        1,225,143
Dividends payable.......................................................................          137,968
Accrued expenses and other liabilities..................................................           28,373
Due to broker-variation margin payable..................................................           21,094
Due to Distributors.....................................................................           18,678
Deferred trustees' fees.................................................................            1,010
                                                                                           ---------------
  Total liabilities.....................................................................        2,918,391
                                                                                           ---------------
Net Assets..............................................................................    $ 146,615,378
                                                                                           ---------------
                                                                                           ---------------
Net assets were comprised of:
  Shares of beneficial interest, at par.................................................    $     147,916
  Paid-in capital in excess of par......................................................      148,439,262
                                                                                           ---------------
                                                                                              148,587,178
  Accumulated net realized loss on investments..........................................         (663,319)
  Net unrealized depreciation on investments............................................       (1,308,481)
                                                                                           ---------------
  Net assets, August 31, 1994...........................................................    $ 146,615,378
                                                                                           ---------------
                                                                                           ---------------
Class A:
  Net asset value and redemption price per share ($134,848,886 / 13,604,715 shares of
    beneficial interest issued and outstanding).........................................           $ 9.91
  Maximum sales charge (3.0% of offering price).........................................             0.31
                                                                                           ---------------
  Maximum offering price to public......................................................           $10.22
                                                                                           ---------------
                                                                                           ---------------
Class B:
  Net asset value, offering price and redemption price per share ($581,525 / 58,698
    shares of
    beneficial interest issued and outstanding).........................................           $ 9.91
                                                                                           ---------------
                                                                                           ---------------
Class C:
  Net asset value, offering price and redemption price per share ($11,184,967 /
    1,128,212 shares of
    beneficial interest issued and outstanding).........................................           $ 9.91
                                                                                           ---------------
                                                                                           ---------------
</TABLE>
 
See Notes to Financial Statements.
                                      -9-

<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 FLORIDA SERIES
 Statement of Operations
<TABLE>
<CAPTION>
                                         Year Ended
                                         August 31,
Net Investment Income                       1994
                                        ------------
<S>                                     <C>
Income
  Interest...........................   $  9,161,364
                                        ------------
Expenses
  Management fee, net waiver of
  $467,337...........................        311,558
  Distribution fee--Class A, net
    waiver of $134,896...............         11,593
  Distribution fee--Class B..........             47
  Distribution fee--Class C..........         69,602
  Custodian's fees and expenses......         85,000
  Transfer agent's fees and
  expenses...........................         53,000
  Reports to shareholders............         49,500
  Registration fees..................         30,000
  Legal fees.........................         20,000
  Audit fee..........................         10,500
  Amortization of deferred
    organization expense.............          7,273
  Trustees' fees.....................          3,375
  Miscellaneous......................         11,459
                                        ------------
    Total expenses...................        662,907
Less: expense subsidy (Note 4).......       (270,113)
                                        ------------
    Net expenses.....................        392,794
                                        ------------
Net investment income................      8,768,570
                                        ------------
Realized and Unrealized Gain (Loss)
on Investments
Net realized gain (loss) on:
  Investment transactions............       (694,251)
  Financial futures contract
  transactions.......................        685,575
                                        ------------
                                              (8,676)
                                        ------------
Net change in unrealized
  appreciation/depreciation on:
  Investments........................    (12,025,930)
  Financial futures contracts........        155,094
                                        ------------
                                         (11,870,836)
                                        ------------
Net loss on investments..............    (11,879,512)
                                        ------------
Net Decrease in Net Assets Resulting
from Operations......................   $ (3,110,942)
                                        ------------
                                        ------------
</TABLE>
 
 PRUDENTIAL MUNICIPAL SERIES FUND
 FLORIDA SERIES
 Statement of Changes in Net Assets
<TABLE>
<CAPTION>
                               Year Ended August 31,
Increase (Decrease)        -----------------------------
in Net Assets                  1994            1993
                           -------------   -------------
<S>                        <C>             <C>
Operations
  Net investment
  income.................  $   8,768,570   $   7,354,295
  Net realized gain
    (loss) on investment
    transactions.........         (8,676)      2,571,909
  Net change in
    unrealized
appreciation/depreciation
    of investments.......    (11,870,836)      6,419,976
                           -------------   -------------
  Net increase (decrease)
    in net assets
    resulting from
    operations...........     (3,110,942)     16,346,180
                           -------------   -------------
Dividends and distributions (Note 1):
  Dividends to
    shareholders from
    investment income
  Class A................     (8,305,093)     (7,348,931)
  Class B................           (582)             --
  Class C................       (462,895)         (5,364)
                           -------------   -------------
                              (8,768,570)     (7,354,295)
                           -------------   -------------
  Distributions to
    shareholders from net
    realized gains
  Class A................     (2,821,851)     (1,396,748)
  Class B................             --              --
  Class C................       (142,331)             --
                           -------------   -------------
                              (2,964,182)     (1,396,748)
                           -------------   -------------
Series share transactions (Note 6)
  Net proceeds from
    shares sold..........     35,379,732      52,329,243
  Net asset value of
    shares issued in
    reinvestment of
    dividends and
    distributions........      5,323,495       3,739,870
  Cost of shares
  reacquired.............    (31,275,509)    (15,967,441)
                           -------------   -------------
  Net increase in net
    assets from Series
    share transactions...      9,427,718      40,101,672
                           -------------   -------------
Total increase
  (decrease).............     (5,415,976)     47,696,809
Net Assets
Beginning of year........    152,031,354     104,334,545
                           -------------   -------------
End of year..............  $ 146,615,378   $ 152,031,354
                           -------------   -------------
                           -------------   -------------
</TABLE>
 
See Notes to Financial Statements.        See Notes to Financial Statements.
                                      -10-

<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 FLORIDA SERIES
 Notes to Financial Statements

   Prudential Municipal Series Fund, (the ``Fund'') is registered under the
Investment Company Act of 1940, as an open-end investment company. The Fund was
organized as a Massachusetts business trust on May 18, 1984 and consists of
seventeen series. The monies of each series are invested in separate,
independently managed portfolios. The Florida Series (the ``Series'') commenced
investment operations on December 28, 1990. The Series is non-diversified and
seeks to achieve its investment objective of providing the maximum amount of
income that is exempt from federal income taxes with the minimum of risk, and
investing in securities which will enable its shares to be exempt from the
Florida intangibles tax by investing in ``investment grade'' tax-exempt
securities whose ratings are within the four highest ratings categories by a
nationally recognized statistical rating organization or, if not rated, are of
comparable quality. The ability of the issuers of the securities held by the
Series to meet their obligations may be affected by economic developments in a
specific state, industry or region.
                              
Note 1. Accounting            The following is a summary
Policies                      of significant accounting poli-
                              cies followed by the Fund, and the Series, in the
preparation of its financial statements.

Securities Valuations: The Fund values municipal securities (including
commitments to purchase such securities on a ``when-issued'' basis) on the basis
of prices provided by a pricing service which uses information with respect to
transactions in bonds, quotations from bond dealers, market transactions in
comparable securities and various relationships between securities in
determining values. If market quotations are not readily available from such
pricing service, a security is valued at its fair value as determined under
procedures established by the Trustees.

   Short-term securities which mature in more than 60 days are valued at current
market quotations. Short-term securities which mature in 60 days or less are
valued at amortized cost.

   All securities are valued as of 4:15 P.M., New York time.

Financial Futures Contracts: A financial futures contract is an agreement to
purchase (long) or sell (short) an agreed amount of debt securities at a set
price for delivery on a future date. Upon entering into a financial futures
contract, the Series is required to pledge to the broker an amount of cash
and/or other assets equal to a certain percentage of the contract amount. This
amount is known as the ``initial margin''. Subsequent payments, known as
``variation margin'', are made or received by the Series each day, depending on
the daily fluctuations in the value of the underlying security. Such variation
margin is recorded for financial statement purposes on a daily basis as
unrealized gain or loss. The Series invests in financial futures contracts
solely for the purpose of hedging its existing portfolio securities or
securities the Series intends to purchase against fluctuations in value caused
by changes in prevailing market interest rates. Should interest rates move
unexpectedly, the Series may not achieve the anticipated benefits of the
financial futures contracts and may realize a loss. The use of futures
transactions involves the risk of imperfect correlation in movements in the
price of futures contracts, interest rates and the underlying hedged assets.

Securities Transactions and Investment Income: Securities transactions are
recorded on the trade date. Realized gains and losses on sales of securities are
calculated on the identified cost basis. Interest income is recorded on the
accrual basis. The Series amortizes premiums and original issue discount paid on
purchases of portfolio securities as adjustments to interest income.

   Net investment income (other than distribution fees) and unrealized and
realized gains or losses are allocated daily to each class of shares based upon
the relative proportion of net assets of each class at the beginning of the day.
Federal Income Taxes: For federal income tax purposes, each series in the Fund
is treated as a separate taxpaying entity. It is the intent of the Series to
meet the requirements of the Internal Revenue Code applicable to regulated
investment companies and to distribute all of its net income to shareholders.
For this reason and because substantially all of the Series' gross income
consists of tax-exempt interest, no federal income tax provision is required.

Dividends and Distributions: The Series declares daily dividends from net
investment income. Payment of dividends is made monthly. Distributions of net
capital gains, if any, are made annually.
   Income distributions and capital gain distributions are determined in
accordance with income tax regulations which may differ from generally accepted
accounting principles.
                                      -11-

<PAGE>
Deferred Organization Expenses: The Series incurred approximately $32,000 in
organization and initial registration expenses. Such amount has been deferred
and is being amortized over a period of 60 months ending December, 1995.
                              
Note 2. Agreements            The Fund has a management
                              agreement with Prudential Mutual Fund Management,
Inc. (``PMF''). Pursuant to this agreement, PMF has responsibility for all
investment advisory services and supervises the subadviser's performance of such
services. PMF has entered into a subadvisory agreement with The Prudential
Investment Corporation (``PIC''); PIC furnishes investment advisory services in
connection with the management of the Fund. PMF pays for the cost of the
subadviser's services, the compensation of officers of the Fund, occupancy and
certain clerical and bookkeeping costs of the Fund. The Fund bears all other
costs and expenses.

   The management fee paid PMF is computed daily and payable monthly, at an
annual rate of .50 of 1% of the average daily net assets of the Series. During
the year ended August 31, 1994, PMF waived 60% of its management fee, which
amounted to $467,337 ($.03 per share for Class A and C shares; .30% of average
net assets). The Series is not required to reimburse PMF for such waiver.

   The Fund has distribution agreements with Prudential Mutual Fund
Distributors, Inc. (``PMFD''), which acts as the distributor of the Class A
shares of the Fund, and with Prudential Securities Incorporated (``PSI''), which
acts as distributor of the Class B and Class C shares of the Fund (collectively
the ``Distributors''). The Fund compensates the Distributors for distributing
and servicing the Fund's Class A, Class B and Class C shares, pursuant to plans
of distribution, (the ``Class A, B and C Plans'') regardless of expenses
actually incurred by them. The distribution fees are accrued daily and payable
monthly.

   On July 19, 1994, shareholders of the Fund approved amendments to the Class A
distribution plan under which the distribution plan became a compensation plan,
effective August 1, 1994. Prior thereto, the distribution plan was a
reimbursement plan, under which PMFD was reimbursed for expenses actually
incurred by them up to the amount permitted under the Class A Plan. The Fund is
not obligated to pay any prior or future excess distribution costs (costs
incurred by the Distributor in excess of distribution fees paid by the Fund).
The rate of the distribution fees charged to Class A shares of the Fund did not
change under the amended plan of distribution.

   Pursuant to the Class A, B and C Plans, the Fund compensates the Distributors
for distribution-related activities at an annual rate of up to .30 of 1%, .50 of
1% and .75 of 1%, of the average daily net assets of the Class A, B and C
shares, respectively. With respect to the Class A Plan, PMFD voluntarily agreed
to waive its distribution fee, currently limited to .10 of 1% of average net
assets for the period September 1, 1993 through July 31, 1994. Effective August
1, 1994, PMFD eliminated its waiver. The amount of distribution fees waived by
PMFD was $134,896 ($.01 per share for Class A shares; .10% of average net
assets) for the fiscal year ended August 31, 1994. Expenses under the Class B
and C Plans were .50 of 1% and .75 of 1% of the average daily net assets,
respectively, for the fiscal year ended August 31, 1994.

   PMFD has advised the Series that it has received approximately $880,300 in
front-end sales charges resulting from sales of Class A shares during the fiscal
year ended August 31, 1994. From these fees, PMFD paid such sales charges to PSI
and Pruco Securities Corporation, affiliated broker-dealers, which in turn paid
commissions to salespersons and incurred other distribution costs.

   PMFD is a wholly-owned subsidiary of PMF; PSI, PMF and PIC are indirect,
wholly-owned subsidiaries of The Prudential Insurance Company of America.
                              
Note 3. Other                 Prudential Mutual Fund Ser-
Transactions                  vices, Inc. (``PMFS''), a 
with Affiliates               wholly owned subsidiary of 
                              PMF, serves as the Fund's transfer agent. During
the year ended August 31, 1994, the Series incurred fees of approximately
$44,600 for the services of PMFS. As of August 31, 1994, approximately $3,700 of
such fees were due to PMFS. Transfer agent fees and expenses in the Statement of
Operations include certain out-of-pocket expenses paid to non-affiliates.
                              
Note 4. Expense               PMF voluntarily subsidized all
Subsidy                       operating expenses (except 
                              management and distribution fees) of the Class A,
Class B and Class C shares of the Series until further notice. For the year
ended August 31, 1994, PMF subsidized $270,113 ($.02 per share for Class A and C
shares; .17% of average net assets) of the Series' expenses. The Series is not
required to reimburse PMF for such subsidy.
                              
Note 5. Portfolio             Purchases and sales of port-
Securities                    folio securities, excluding 
                              short-term investments, for the year ended August
31, 1994 were $126,882,962 and $111,569,126, respectively.

   The cost basis of investments for federal income tax purposes as of August
31, 1994 was $145,737,067 and,
                                      -12-

<PAGE>
accordingly, net unrealized depreciation $1,395,512 (gross unrealized
appreciation--$3,604,800; gross unrealized depreciation--$5,000,312).

   The Series will elect to treat net capital losses of approximately $573,400
incurred in the ten month period ended August 31, 1994 as having been incurred
in the following fiscal year.

   At August 31, 1994 the Series sold 75 financial futures contracts on the
Municipal Bond Index expiring in September 1994. The value at disposition of
such contracts was $6,948,281. The value of such contracts on August 31, 1994
was $6,862,500, thereby resulting in an unrealized gain of $85,781.
                              
Note 6. Capital               The Series currently offers
                              Class A, Class B and Class C shares. Class A
shares are sold with a front-end sales charge of up to 3.0%. Class B shares are
sold with a contingent deferred sales charge which declines from 5% to zero
depending on the period of time the shares are held. Class C shares, which prior
to August 1, 1994 were known as D shares, are sold with a contingent deferred
sales charge of 1% during the first year. Class B shares will automatically
convert to Class A shares on a quarterly basis approximately seven years after
purchase commencing in February 1995. Offering of Class B shares commenced on
August 1, 1994.

   The Fund has authorized an unlimited number of shares of beneficial interest
at $.01 par value per share. Transactions in shares of beneficial interest for
the years ended August 31, 1994 and 1993 were as follows:

<TABLE>
<CAPTION>
Class A                            Shares         Amount
- ------------------------------   ----------    ------------
<S>                              <C>           <C>
Year ended August 31, 1994:
Shares sold...................    2,274,149    $ 24,062,897
Shares issued in reinvestment
  of dividends and
  distributions...............      475,125       4,935,129
Shares reacquired.............   (2,838,050)    (29,205,030)
                                 ----------    ------------
Net increase in shares
  outstanding.................      (88,776)   $   (207,004)
                                 ----------    ------------
                                 ----------    ------------
Year ended August 31, 1993:
Shares sold...................    4,710,788    $ 49,235,380
Shares issued in reinvestment
  of dividends and
  distributions...............      358,775       3,737,322
Shares reacquired.............   (1,530,543)    (15,961,401)
                                 ----------    ------------
Net increase in shares
  outstanding.................    3,539,020    $ 37,011,301
                                 ----------    ------------
                                 ----------    ------------
<CAPTION>
Class B                            Shares         Amount
- ------------------------------   ----------    ------------
<S>                              <C>           <C>
August 1, 1994* through
  August 31, 1994:
Shares sold...................       58,689    $    579,300
Shares issued in reinvestment
  of dividends................           24             235
Shares reacquired.............          (15)           (150)
                                 ----------    ------------
Net increase in shares
  outstanding.................       58,698    $    579,385
                                 ----------    ------------
                                 ----------    ------------
</TABLE>
 
- ------------------
* Commencement of offering of Class B shares.

<TABLE>
<CAPTION>
<S>                              <C>           <C>
Class C
- ------------------------------
Year ended August 31, 1994:
Shares sold...................    1,004,802    $ 10,737,535
Shares issued in reinvestment
  of dividends and
  distributions...............       37,628         388,131
Shares reacquired.............     (202,212)     (2,070,329)
                                 ----------    ------------
Net increase in shares
  outstanding.................      840,218    $  9,055,337
                                 ----------    ------------
                                 ----------    ------------
July 26, 1993* through
  August 31, 1993:
Shares sold...................      288,326    $  3,093,863
Shares issued in reinvestment
  of dividends................          235           2,548
Shares reacquired.............         (567)         (6,040)
                                 ----------    ------------
Net increase in shares
  outstanding.................      287,994    $  3,090,371
                                 ----------    ------------
                                 ----------    ------------
</TABLE>
 
- ------------------
* Commencement of offering of Class C shares.
                                      -13-

<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 FLORIDA SERIES
 Financial Highlights
<TABLE>
<CAPTION>
                                                     Class A                              Class B               Class C
                             -------------------------------------------------------    -----------    --------------------------
                                                                       December 28,      August 1,                     July 26,
                                                                           1990*        1994(D)(D)(D)     Year        1993(D)(D)
                                     Years Ended August 31,               Through         through         Ended         Through
                             --------------------------------------     August 31,      August 31,     August 31,     August 31,
                                1994          1993          1992           1991            1994           1994           1993
                             ----------    ----------    ----------    -------------    -----------    -----------    -----------

<S>                          <C>           <C>           <C>           <C>              <C>            <C>            <C>

PER SHARE OPERATING
  PERFORMANCE:
Net asset value, beginning
  of period...............    $   10.87     $   10.27     $    9.76       $  9.55         $    9.95      $   10.87      $   10.58
                             ----------    ----------    ----------    -------------    -----------    -----------    -----------
Income from investment
  operations

Net investment
  income(D)...............          .59           .57           .65           .44               .04            .48            .03

Net realized and
  unrealized gain (loss)
  on investment
  transactions............         (.76)          .73           .51           .21              (.04)          (.76)           .29
                             ----------    ----------    ----------    -------------    -----------    -----------    -----------
  Total from investment
    operations............         (.17)         1.30          1.16           .65                --           (.28)           .32
                             ----------    ----------    ----------    -------------    -----------    -----------    -----------
Less distributions

Dividends from net
  investment income.......         (.59)         (.57)         (.65)         (.44)             (.04)          (.48)          (.03)

Distributions from net
  realized gains..........         (.20)         (.13)           --            --                --           (.20)            --
                             ----------    ----------    ----------    -------------    -----------    -----------    -----------
  Total distributions.....         (.79)         (.70)         (.65)         (.44)             (.04)          (.68)          (.03)
                             ----------    ----------    ----------    -------------    -----------    -----------    -----------
Net asset value, end of
  period..................    $    9.91     $   10.87     $   10.27       $  9.76         $    9.91      $    9.91      $   10.87
                             ----------    ----------    ----------    -------------    -----------    -----------    -----------
                             ----------    ----------    ----------    -------------    -----------    -----------    -----------
TOTAL RETURN#:............        (1.69)%       13.78%        12.26%         6.90%            (0.05)%        (2.40)%         3.14%
RATIOS/SUPPLEMENTAL DATA:

Net assets, end of period
  (000)...................     $134,849      $148,900      $104,335       $63,929              $582        $11,185         $3,132

Average net assets
  (000)...................     $146,489      $123,820      $ 82,893       $41,528              $118        $ 9,280         $1,038

Ratios to average net
  assets(D):
  Expenses, including
    distribution fees.....          .20%          .20%         0.09%            0               .70%**         .95%           .95%**

  Expenses, excluding
    distribution fees.....          .20%          .20%         0.09%            0               .20%**         .20%           .20%**

  Net investment income...         5.67%         5.94%         6.41%         6.68%**           6.21%**        4.99%          5.19%**

Portfolio turnover........           75%           68%           56%           39%               75%            75%            68%

 
- ---------------
             * Commencement of investment operations.
            ** Annualized.
           (D) Net of expense subsidy and fee waiver.
        (D)(D) Commencement of offering of Class C shares. Prior to 
               August 1, 1994, Class C shares were called Class
               D shares.
     (D)(D)(D) Commencement of offering of Class B shares.
             # Total return does not consider the effects of sales loads. Total
               return is calculated assuming a purchase of shares on the first 
               day and a sale on the last day of each period reported and 
               includes reinvestment of dividends and distributions. Total 
               returns for periods of less than a full year are not annualized.
</TABLE>
See Notes to Financial Statements.
                                      -14-
 <PAGE>
<PAGE>
                          INDEPENDENT AUDITORS' REPORT

The Shareholders and Board of Trustees
Prudential Municipal Series Fund, Florida Series

   We have audited the accompanying statement of assets and liabilities of
Prudential Municipal Series Fund, Florida Series, including the portfolio of
investments, as of August 31, 1994, the related statements of operations for the
year then ended and of changes in net assets for each of the two years in the
period then ended and the financial highlights for each of the three years in
the period then ended and for the period December 28, 1990 (commencement of
investment operations) through August 31, 1991. These financial statements and
financial highlights are the responsibility of the Fund's management. Our
responsibility is to express an opinion on these financial statements and
financial highlights based on our audits.

   We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements and financial
highlights are free of material misstatement. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements. Our procedures included confirmation of the securities owned as of
August 31, 1994 by correspondence with the custodian and brokers; where replies
were not received from brokers, we performed other auditing procedures. An audit
also includes assessing the accounting principles used and significant estimates
made by management, as well as evaluating the overall financial statement
presentation. We believe that our audits provide a reasonable basis for our
opinion.

   In our opinion, such financial statements and financial highlights present
fairly, in all material respects, the financial position of Prudential Municipal
Series Fund, Florida Series, as of August 31, 1994, the results of its
operations, the changes in its net assets, and its financial highlights for the
respective stated periods in conformity with generally accepted accounting
principles.

Deloitte & Touche LLP
New York, New York
October 17, 1994

                         FEDERAL INCOME TAX INFORMATION

   We are required by the Internal Revenue Code to advise you within 60 days of
the Series' fiscal year end (August 31, 1994) at to the federal tax status of
dividends paid by the Series during such fiscal year. Accordingly, we are
advising you that in the fiscal year ended August 31, 1994, dividends paid from
net investment income of $.59 per Class A share, $.04 per Class B share and $.48
per Class C share were all federally tax-exempt interest dividends. In addition,
the Series paid to both A and C shares a long-term capital gain distribution of
$.044 per share which is taxable as such and a short-term capital gain
distribution of $.155 which is taxable as ordinary income.

   In January 1995, you will be advised on IRS Form 1099 DIV or substitute 1099
DIV as to the federal tax status of the distributions received by you in
calendar year 1994.
                                      -15-

<PAGE>
      These graphs are furnished to you in accordance with SEC regulations. They
compare a $10,000 investment in Prudential Municipal Series Fund: Florida Series
(Class A, Class B, and Class C) with a similar investment in the Lehman Brothers
Municipal Bond Index (the Index) by portraying the initial account values at the
commencement of operations of each class and subsequent account values at the
end of each fiscal year (August 31) beginning in 1990 for Class A, in 1994 for
Class B shares and 1993 for Class C shares. For purposes of the graphs and,
unless otherwise indicated, the accompanying tables, it has been assumed that
(a) the maximum sales charge was deducted from the initial $10,000 investment in
Class A shares; (b) the maximum applicable contingent deferred sales charge was
deducted from the value of the investment in Class B shares and Class C shares,
assuming full redemption on August 31, 1994; (c) all recurring fees (including
management fees) were deducted; and (d) all dividends and distributions were
reinvested. Class B shares will automatically convert to Class A shares on a
quarterly basis approximately seven years after purchase. This conversion
feature is expected to be implemented on or about February 1995 and is not
reflected in the graph. The graph and accompanying tables reflect the past
subsidy and/or waiver of expenses and/or management fees. Without fee waivers
and expense subsidies, the value of a $10,000 investment in the Series and the
Series' average annual total return, as shown above, would have been lower.

      The Index is a weighted index comprised of 21,000 municipal bonds (general
obligation bonds, revenue bonds, insured bonds and prerefunded bonds) selected
by Lehman Brothers as representative of the long-term investment grade municipal
bond market. The Index is an unmanaged index and includes the reinvestment of
all income, but does not reflect the payment of transaction costs and advisory
fees associated with an investment in the Series. The securities which comprise
the Index may differ substantially from the securities in the Series' portfolio
because the Index, among other things, is not state specific. The Lehman
Brothers Municipal Bond Index is not the only index which may be used to
characterize performance of long-term, investment-grade tax-exempt bond funds
and other indexes may portray different comparative performance.
                                      -16-

<PAGE)

Trustees
Edward D. Beach
Eugene C. Dorsey
Delayne Dedrick Gold
Harry A. Jacobs, Jr.
Lawrence C. McQuade
Thomas T. Mooney
Thomas H. O'Brien
Richard A. Redeker
Nancy Hays Teeters

Officers
Lawrence C. McQuade, President
Robert F. Gunia, Vice President
Susan C. Cote, Treasurer
S. Jane Rose, Secretary
Ronald Amblard, Assistant Secretary
Deborah A. Docs, Assistant Secretary

Manager
Prudential Mutual Fund Management, Inc.
One Seaport Plaza
New York, NY 10292

Investment Adviser
The Prudential Investment Corporation
Prudential Plaza
Newark, NJ 07101

Distributors
Prudential Mutual Fund Distributors, Inc.
Prudential Securities Incorporated
One Seaport Plaza
New York, NY 10292

Custodian
State Street Bank and Trust Company
One Heritage Drive
North Quincy, MA 02171

Transfer Agent
Prudential Mutual Fund Services, Inc.
P.O. Box 15005
New Brunswick, NJ 08906

Independent Accountants
Deloitte & Touche LLP
1633 Broadway
New York, NY 10019

Legal Counsel
Gardner, Carton & Douglas
Quaker Tower
321 North Clark Street
Chicago, IL 60610-4795

Prudential Mutual Funds
One Seaport Plaza
New York, NY 10292
Toll free (800) 225-1852, Collect (908) 417-7555

This report is not authorized for distribution to prospective investors
unless preceded or accompanied by a current prospectus.

74435M507
74435M614                                MF 148E
74435M606       (LOGO)             Cat. #4443525



























ANNUAL REPORT                                    August 31, 1994

Prudential
Municipal
Series Fund

(ICON)

Georgia Series

(LOGO)
<PAGE>
Letter to Shareholders

October 18, 1994 

Dear Shareholder:

It has been a most difficult year in the U.S. financial markets.  When 
we last wrote in February  interest rates were starting to rise, 
ending a three-year long bull market in bonds. What started as a trickle 
has become a torrent.  Interest rates have continued to increase this 
year, sending bond prices down sharply.  Of course, as interest rates 
rise, bond prices decline.  In this environment of falling prices and 
unusual volatility, your Prudential Municipal Series Fund -- Georgia 
Series sought to minimize risk while maximizing your tax-free income.

The Series seeks maximum income exempt from Georgia state and federal 
income taxes* consistent with preservation of capital.  The Series is 
comprised of investment grade municipal obligations with an average 
credit quality of Aa/AA, as determined by Moody's Investors Service 
or Standard & Poor's Ratings Group.  The Series performed in line 
with the Lipper Georgia Municipal Debt Average over the last year, 
but because long-term interest rates rose, total returns were 
disappointing.  As a result, the Series has become more cautious 
and shortened its average maturity.

<TABLE>
                         SERIES PERFORMANCE 
                        As of August 31, 1994
<CAPTION>
                          30-day               Taxable Equivalent Yields  
            NAV          SEC Yield            @28%       @31%      @39.6%
<S>       <C>            <C>                  <C>        <C>        <C>
Class A   $11.19            4.0%              6.0%       6.2%       7.1%
Class B   $11.19            3.8%              5.7%       5.8%       6.6% 
Class C   $11.19            N/A               N/A        N/A        N/A
</TABLE>

Investment return and principal value will fluctuate so that an 
investor's shares, when redeemed, may be worth more or less than 
their original cost.  Past performance is no guarantee of future 
results.

*Interest on municipal obligations may be subject to the federal 
alternative minimum tax. See your Series' prospectus for more details.

N/A = Yield information with respect to Class C is not available 
as operations commenced in August 1994.

                                    -1-
<PAGE>

<TABLE>
                                TOTAL RETURNS
<CAPTION>
                   Historical (As of 8/31/94)1       Average Annual (As of 9/30/94)2
                  1-Yr.   5-Yr.  Since Incep.**     1-Yr.     5-Yr.  Since Incep.**
<S>               <C>     <C>      <C>              <C>       <C>        <C>
Class A           -1.6%   N/A       +38.3%          -7.7%     N/A        +6.0%
Class B           -2.0%  +39.4%    +127.0%         -10.2%    +6.4%       +8.3%
Class C            N/A    N/A        -0.1%           N/A      N/A        -3.1%
Lipper GA 
Muni Debt Avg.***  +1.6% +43.1%    +143.6%           N/A      N/A         N/A
</TABLE>

1 Source: Lipper Analytical Services, Inc. These figures do not take 
into account sales charges.

2 Source: Prudential Mutual Fund Management, Inc.  These averages take 
into account applicable sales charges.  The Series charges a maximum 
initial sales charge of 3% for Class A shares.  Class B shares are 
subject to a declining contingent deferred sales charge of 5%, 4%, 3%, 
2%, 1% and 1%, respectively, for the first six years.  Class B shares 
will automatically convert to Class A shares approximately seven years 
after purchase.  This conversion feature is expected to be implemented 
in February 1995.  Class C shares are sold subject to a contingent 
deferred sales charge of 1% during the first year. 

**Inception on January 22, 1990 for Class A, September 25, 1984 for 
Class B and August 1, 1994 for Class C.

***These are the average returns of 20 Georgia municipal debt funds 
for one-year, five-year, and since inception of Class B shares, as 
determined by Lipper Analytical Services, Inc.

Note:  Without expense subsidies and management fee waivers, the 
Series' historical and average annual total returns would have been 
lower.  The Series' Class B average annual total return since inception 
would have been 8.1%

Once Was Not Enough

When we wrote to you in February, the Federal Reserve raised short-term 
interest rates for the first time in years, hoping to control inflation.  
Since then, the Fed has moved four more times, until the federal funds 
rate (the overnight interbank lending rate) now stands at 4.75%, up from 
3% at the start of the year.  The Fed also increased the discount rate 
(at which it lends banks money) to 4% from 3% over the same period.

Interest rates rise when the financial markets fear inflation, the bond 
holder's enemy. Inflation is feared because it robs purchasing power from 
a bond's fixed-interest rate.

Municipal bond interest rates increased by nearly a percentage point, 
to 6.46% on August 25 from 5.52% on December 29, 1993, as measured by 
the Bond Buyer's Revenue Bond Index, a widely used yardstick of interest 
rates in the tax-free market.

Georgia: Strong Financial Position

As a state government, Georgia has one of the strongest financial positions 
in the country.  Because of its solid economic growth, the state cut both 
taxes and spending, and is still expected to end the fiscal year with a 
surplus.  In addition, the state has a reserve of $220 million and growing, 
should it face any unforeseen financial difficulty.  Georgia's latest budget 
includes welfare reform with a work requirement, business and low-income tax 
cuts, an increase in 

                                    -2-
<PAGE>


personal income tax exemptions and sales tax exemptions.
If revenues continue to come in ahead of budget, other tax cuts may be 
considered.

Georgia's debt position is excellent.  Virtually all debt is either 
general obligation or state-guaranteed.  It is among the states with 
the highest credit ratings.

Because of the state's fiscal strength, the Series has concentrated 
its investments in local and school district bonds.

A Tax Reminder

As a result of the federal Revenue Reconciliation Act of 1993, which 
affects bonds purchased after April 30, 1993,  it is possible that 
this year you may have some taxable income from your tax-free municipal 
bond fund.  The law stipulates that the portion of any gain realized on 
the sale or retirement of a tax-free bond purchased at a market discount 
to its face value must be taxed as ordinary income.  

As a result of this change in federal tax law, some discount bonds have 
been selling at levels so cheap they will produce a higher after-tax 
return than other bonds not subject to the provisions of the new law.  
We have occasionally taken advantage of this market imbalance because we 
have determined that at very low prices these bonds can still provide you 
with a higher after-tax return on your investment.

The Outlook

We expect volatility in the municipal bond market until the economy 
reaches a level of growth that is sustainable without causing inflation.  
If the economy continues to surge, the ever vigilant Fed will move again, 
boosting short-term rates.  If the economy slows substantially, 
long-term rates should stabilize.  Although rates may keep rising, 
we believe that most of the increase is now behind us. 

In the months ahead, we expect supply -- or the lack of it -- to 
become more important in the tax-free municipal bond market.  Through 
the first eight months of the year, new issue volume is off 42%,  
according to Securities Data Co., which tracks this statistic.  The 
pace is accelerating.  In August, new issue volume fell 56%.  

                                    -3-
<PAGE>

As always, it is a pleasure to have you as a shareholder in the 
Prudential Municipal Series Fund -- Georgia Series, and to take 
this opportunity to report our activities to you.

Sincerely,

Lawrence C. McQuade
President

Marie Conti
Portfolio Manager


                                    -4-

<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                    Portfolio of Investments
GEORGIA SERIES                                               August 31, 1994
<TABLE>
<CAPTION>
  Moody's     Principal                                                 
   Rating      Amount                                   Value            
(Unaudited)     (000)          Description (a)         (Note 1)       
<S>           <C>          <C>                       <C>
                           LONG-TERM INVESTMENTS--97.2%
                           Atlanta Urban Res. Fin.
                             Auth.,
                             Dorm. Fac. Rev.,
                             Atlanta Gen. Oblig.,
Aa             $    585(D) 7.10%, 12/1/10..........  $   653,240
                           Clark Atlanta Univ.
                             Proj.,
NR                  935(D) 9.25%, 6/1/10...........    1,142,926
                           Atlanta Wtr. & Swr.
                             Rev.,
Aa                  500    4.75%, 1/1/23...........      398,710
                           Bartow Cnty. Sch. Dist.,
                             Gen. Oblig.,
Aaa                 500    5.70%, 5/1/14,
                             M.B.I.A...............      478,870
                           Clarke Cnty. Sch. Dist.,
Aaa                 425    5.50%, 7/1/08,
                             F.G.I.C...............      415,310
                           Clayton Cnty. Solid
                             Waste Mgmt. Auth.
                             Rev.,
Aa                  500    6.50%, 2/1/12, Ser. A...      512,685
                           Clayton Cnty. Wtr.
                             Auth.,
                             Wtr. & Sewage Rev.,
Aaa                 500(D) 6.65%, 5/1/12...........      552,730
                           Cobb Cnty. Kennestone
                             Hosp.,
                             Auth. Rev.,
                           5.00%, 4/1/24, Ser. A,
Aaa                 750    M.B.I.A.................      618,173
                           Columbus Hosp. Auth.
                             Rev.,
                             Antic. Cert., St.
                             Francis Hosp.,
Aaa                 500    8.25%, 1/1/07, B.I.G....      548,650
                           DeKalb Cnty. Wtr. & Swr.
                             Rev.,
Aa                  750    5.25%, 10/1/23..........      649,995
                           DeKalb Private Hosp.
                             Auth. Rev.,
                             Wesley Svcs. Inc.
                             Proj.,
Aa3                 500    8.25%, 9/1/15...........      526,385
                           Douglasville-Douglas
                             Cnty.,
                             Wtr. & Swr. Auth.
                             Rev.,
Aaa                 750    5.625%, 6/1/15,
                             A.M.B.A.C.............      709,980
                           Downtown Savannah Auth.
                             Rev., Chatham Co.
                             Proj.,
Aa                  250    5.00%, 1/1/11...........      221,790
                           Floyd Cnty. Wtr. & Swr.
                             Rev.,
Aaa                 250    5.10%, 11/1/13,
                             F.G.I.C...............      220,148
                           Forsyth Cnty. Sch. Dist.
                             Dev. Rev.,
A1             $    500    6.75%, 7/1/16, Ser. A...  $   542,050
                           Fulco Hosp. Auth. Rev.,
                             Antic. Cert., Baptist
                             Hlth.,
A                   750    6.375%, 9/1/22, Ser.
                             B.....................      690,203
                           Shepherd Spinal Ctr.
                             Proj.,
Aa3                 750    7.75%, 10/1/08, Ser.
                             A.....................      801,487
                           Fulton Cnty. Bldg. Auth.
                             Rev.,
                             Human Res. & Gov't.
                             Facs. Proj.,
Aa                  250    7.00%, 1/1/10...........      268,887
                           Judicial Ctr. Proj.,
Aa                1,325    Zero Coupon, 1/1/11.....      486,434
                           Fulton Cnty. Sch. Dist.
                             Rev.,
                             Lindbrook Square
                             Fndtn.,
Aa                  750@   6.375%, 5/1/17..........      793,162
                           Georgia Mun. Elec. Auth.
                             Pwr.
                             Rev. Ref.,
A1                  250    5.30%, 1/1/07, Ser. Z...      240,563
A1                  250    6.00%, 1/1/14, Ser. A...      243,562
A1                  475    6.25%, 1/1/17, Ser. B...      477,223
                           Georgia Mun. Gas Auth.
                             Rev.,
                             Southern Storage Gas
                             Proj.,
A-*                 600    6.40%, 7/1/14...........      601,164
                           Green Cnty. Dev. Auth.,
                             Ind. Park Rev.,
NR                  680    6.875%, 2/1/04..........      746,905
                           Henry Cnty. Sch. Dist.
                             Dev. Rev.,
A                   750    6.45%, 8/1/11, Ser. A...      779,827
                           Houston Cnty. Georgia
                             Sch. Dist.,
                             Intergovernmental
                             Contract Trust,
Aaa                 250    6.00%, 3/1/14,
                             M.B.I.A...............      248,860
                           Marietta Dev. Auth.
                             Rev.,
                             Life Coll. Inc. Proj.,
Aaa                 500    7.20%, 12/1/09,
                             C.G.I.C...............      543,375
                           Monroe Cnty. Dev. Auth.,
                             Poll. Ctrl. Rev., Gulf
                             Pwr. Co. Proj.,
A2                  500    10.50%, 12/1/14.........      518,600
                           Peach Cnty. Sch. Dist.,
Aaa                 500    6.40%, 2/1/19,
                             M.B.I.A...............      513,330
</TABLE>
 
                                      -5-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                    
GEORGIA SERIES                                               
<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                   Value
(Unaudited)     (000)          Description (a)         (Note 1)
<S>           <C>          <C>                       <C>
                           Puerto Rico Comnwlth.,
                             Gen. Oblig.,
Aaa            $    750    5.40%, 7/1/07,
                             M.B.I.A...............  $   746,497
Aaa                 750    5.50%, 7/1/13,
                             M.B.I.A...............      714,458
Aaa                 450(D)(D) 8.393%, 7/1/20,
                             F.S.A.................      421,875
                           Puerto Rico Hsg. Fin.
                             Corp.,
                             Sngl. Fam. Mtge. Rev.,
                           7.65%, 10/15/22, Ser.
                             1-B,
Aaa                 555    G.N.M.A.................      574,836
                           Savannah Hosp. Auth.
                             Rev.,
                             Candler Hosp.,
Baa                 500    7.00%, 1/1/23...........      489,680
                           Toombs Cnty. Hosp.,
                             Dr. John Meadows Mem.
                             Hosp.,
BBB*                500    7.00%, 12/1/17..........      492,870
                           Virgin Islands Pub. Fin.
                             Auth. Rev., Hwy.
                             Trans. Trust Fund,
NR                  200    7.25%, 10/1/18, Ser.
                             A.....................      206,324
                           Virgin Islands Wtr. &
                             Pwr. Auth., Wtr. Sys.
                             Rev.,
NR                  300    8.50%, 1/1/10, Ser. A...      329,568
                                                     -----------
                           Total long-term
                             investments
                             (cost $19,490,632)....   20,121,332
                                                     -----------
                           SHORT-TERM INVESTMENT--1.4%
                           Georgia Hosp. Equip.
                             Fin. Auth., Pooled
                             Hosp. Loan, Ser. 85,
                           3.25%, 9/1/94, F.R.D.D.
Aaa                 300      (cost $300,000).......      300,000
                                                     -----------
                           Total Investments--98.6%
                           (cost $19,790,632; Note
                             4)....................   20,421,332
                           Other assets in excess
                             of
                             liabilities--1.4%.....      282,079
                                                     -----------
                           Net Assets--100%........  $20,703,411
                                                     -----------
                                                     -----------
</TABLE>
 
(a) The following abbreviations are used in portfolio descriptions:
    A.M.B.A.C.--American Municipal Bond Assurance Corporation.
    B.I.G.--Bond Investors Guaranty Insurance Company.
    C.G.I.C.--Capital Guaranty Insurance Company.
    F.G.I.C.--Financial Guaranty Insurance Company.
    F.R.D.D.--Floating Rate (Daily) Demand Note #.
    F.S.A.--Financial Security Assurance.
    G.N.M.A.--Government National Mortgage Association.
    M.B.I.A.--Municipal Bond Insurance Association.

          # For purposes of amortized cost valuation, the
            maturity date of these securities is considered
            to be the later of the next date on which the
            security can be redeemed at par or the next
            date on which the rate of interest is adjusted.
          * Standard & Poor's rating.
          @ Pledged as initial margin on futures contracts.
        (D) Prerefunded issues are secured by escrowed cash
            and/or direct U.S. guaranteed obligations.
     (D)(D) Inverse floating rate bond. The coupon is
            inversely indexed to a floating interest rate.
            The rate shown is the rate at period end.
 
NR--Not Rated by Moody's or Standard & Poor's.
The Fund's current Statement of Additional Information contains a description of
Moody's and Standard & Poor's ratings.
                                      -6-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 GEORGIA SERIES
 Statement of Assets and Liabilities
<TABLE>
<CAPTION>
Assets                                                                                        August 31, 1994
                                                                                              ---------------
<S>                                                                                           <C>
Investments, at value (cost $19,790,632)...................................................     $20,421,332
Cash.......................................................................................          44,045
Interest receivable........................................................................         336,478
Receivable for Series shares sold..........................................................          23,025
Other assets...............................................................................             780
                                                                                              ---------------
    Total assets...........................................................................      20,825,660
                                                                                              ---------------
Liabilities
Accrued expenses...........................................................................          55,610
Payable for Series shares reacquired.......................................................          29,965
Dividends payable..........................................................................          14,171
Management fee payable.....................................................................           8,830
Distribution fee payable...................................................................           8,444
Due to broker-variation margin.............................................................           4,219
Deferred trustees' fees....................................................................           1,010
                                                                                              ---------------
    Total liabilities......................................................................         122,249
                                                                                              ---------------
Net Assets.................................................................................     $20,703,411
                                                                                              ---------------
                                                                                              ---------------
Net assets were comprised of:
  Shares of beneficial interest, at par....................................................     $    18,498
  Paid-in capital in excess of par.........................................................      20,109,747
                                                                                              ---------------
                                                                                                 20,128,245
  Accumulated net realized loss on investments.............................................         (72,690)
  Net unrealized appreciation on investments...............................................         647,856
                                                                                              ---------------
  Net assets, August 31, 1994..............................................................     $20,703,411
                                                                                              ---------------
                                                                                              ---------------
Class A:
  Net asset value and redemption price per share
    ($1,181,577 / 105,555 shares of beneficial interest issued and outstanding)............          $11.19
  Maximum sales charge (3.0% of offering price)............................................             .35
                                                                                              ---------------
  Maximum offering price to public.........................................................          $11.54
                                                                                              ---------------
                                                                                              ---------------
Class B:
  Net asset value, offering price and redemption price per share
    ($19,521,634 / 1,744,219 shares of beneficial interest issued and outstanding).........          $11.19
                                                                                              ---------------
                                                                                              ---------------
Class C:
  Net asset value, offering price and redemption price per share
    ($199.58 / 17.83 shares of beneficial interest issued and outstanding).................          $11.19
                                                                                              ---------------
                                                                                              ---------------
</TABLE>
 
See Notes to Financial Statements.
                                      -7-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 GEORGIA SERIES
 Statement of Operations
<TABLE>
<CAPTION>
                                          Year Ended
                                          August 31,
Net Investment Income                        1994
                                         ------------
<S>                                      <C>
Income
  Interest...........................    $  1,345,847
                                         ------------
Expenses
  Management fee.....................         108,130
  Distribution fee--Class A..........           1,134
  Distribution fee--Class B..........         102,458
  Custodian's fees and expenses......          58,000
  Registration fees..................          28,000
  Reports to shareholders............          19,500
  Transfer agent's fees and
  expenses...........................          16,000
  Legal fees.........................          15,000
  Audit fee..........................          10,500
  Trustees' fees.....................           3,375
  Miscellaneous......................           1,048
                                         ------------
    Total expenses...................         363,145
                                         ------------
Net investment income................         982,702
                                         ------------
Realized and Unrealized Gain (Loss)
on Investments
Net realized gain (loss) on:
  Investment transactions............         (98,821)
  Financial futures transactions.....          95,281
                                         ------------
                                               (3,540)
                                         ------------
Net change in unrealized
  appreciation/
  depreciation on:
  Investments........................      (1,436,560)
  Financial futures contracts........          28,718
                                         ------------
                                           (1,407,842)
                                         ------------
Net loss on investments..............      (1,411,382)
                                         ------------
Net Decrease in Net Assets
Resulting from Operations............    $   (428,680)
                                         ------------
                                         ------------
</TABLE>
 
 PRUDENTIAL MUNICIPAL SERIES FUND
 GEORGIA SERIES
 Statement of Changes in Net Assets
<TABLE>
<CAPTION>
                               Year Ended August 31,
Increase (Decrease)         ---------------------------
in Net Assets                   1994           1993
                            ------------    -----------
<S>                         <C>             <C>
Operations
  Net investment income...  $    982,702    $   926,363
  Net realized gain (loss)
    on investment
    transactions..........        (3,540)       312,202
  Net change in unrealized
 appreciation/depreciation
    of investments........    (1,407,842)     1,071,362
                            ------------    -----------
  Net increase (decrease)
    in net assets
    resulting from
    operations............      (428,680)     2,309,927
                            ------------    -----------
Dividends and
  distributions (Note 1)
  Dividends from net
    investment income
    Class A...............       (55,820)       (24,841)
    Class B...............      (926,882)      (901,522)
                            ------------    -----------
                                (982,702)      (926,363)
                            ------------    -----------
  Distributions from net
    realized gains
    Class A...............       (15,680)        (8,466)
    Class B...............      (302,050)      (631,421)
                            ------------    -----------
                                (317,730)      (639,887)
                            ------------    -----------
Series share transactions
  (Note 6)
  Net proceeds from shares
    sold..................     3,261,528      4,700,499
  Net asset value of
    shares issued in
    reinvestment of
    dividends and
    distributions.........       863,092      1,006,072
  Cost of shares
    reacquired............    (3,609,847)    (2,411,522)
                            ------------    -----------
  Net increase in net
    assets from Series
    share transactions....       514,773      3,295,049
                            ------------    -----------
Total increase
  (decrease)..............    (1,214,339)     4,038,726
Net Assets
Beginning of year.........    21,917,750     17,879,024
                            ------------    -----------
End of year...............  $ 20,703,411    $21,917,750
                            ------------    -----------
                            ------------    -----------
</TABLE>
 
See Notes to Financial Statements.        See Notes to Financial Statements.
                                      -8-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 GEORGIA SERIES
 Notes to Financial Statements
   Prudential Municipal Series Fund (the ``Fund'') is registered under the
Investment Company Act of 1940, as an open-end investment company. The Fund was
organized as a Massachusetts business trust on May 18, 1984 and consists of
seventeen series. The monies of each series are invested in separate,
independently managed portfolios. The Georgia Series (the ``Series'') commenced
investment operations in September, 1984. The Series is diversified and seeks to
achieve its investment objective of obtaining the maximum amount of income
exempt from federal and applicable state income taxes with the minimum of risk
by investing in ``investment grade'' tax-exempt securities whose ratings are
within the four highest ratings categories by a nationally recognized
statistical rating organization or, if not rated, are of comparable quality. The
ability of the issuers of the securities held by the Series to meet their
obligations may be affected by economic developments in a specific state,
industry or region.
                              
Note 1. Accounting            The following is a summary
Policies                      of significant accounting pol-
                              icies followed by the Fund, and the Series, in the
preparation of its financial statements.
Securities Valuations: The Series values municipal securities (including
commitments to purchase such securities on a ``when-issued'' basis) on the basis
of prices provided by a pricing service which uses information with respect to
transactions in bonds, quotations from bond dealers, market transactions in
comparable securities and various relationships between securities in
determining values. If market quotations are not readily available from such
pricing service, a security is valued at its fair value as determined under
procedures established by the Trustees.
   Short-term securities which mature in more than 60 days are valued at current
market quotations. Short-term securities which mature in 60 days or less are
valued at amortized cost.
   All securities are valued as of 4:15 P.M., New York time.
Financial Futures Contracts: A financial futures contract is an agreement to
purchase (long) or sell (short) an agreed amount of debt securities at a set
price for delivery on a future date. Upon entering into a financial futures
contract, the Series is required to pledge to the broker an amount of cash
and/or other assets equal to a certain percentage of the contract amount. This
amount is known as the ``initial margin''. Subsequent payments, known as
``variation margin'', are made or received by the Series each day, depending on
the daily fluctuations in the value of the underlying security. Such variation
margin is recorded for financial statement purposes on a daily basis as
unrealized gain or loss. The Series invests in financial futures contracts
solely for the purpose of hedging its existing portfolio securities or
securities the Series intends to purchase against fluctuations in value caused
by changes in prevailing market interest rates. Should interest rates move
unexpectedly, the Series may not achieve the anticipated benefits of the
financial futures contracts and may realize a loss. The use of futures
transactions involves the risk of imperfect correlation in movements in the
price of futures contracts, interest rates and the underlying hedged assets.
Securities Transactions and Investment Income: Securities transactions are
recorded on the trade date. Realized gains and losses on sales of securities are
calculated on the identified cost basis. Interest income is recorded on the
accrual basis. The Series amortizes premiums and original issue discount paid on
purchases of portfolio securities as adjustments to interest income.
   Net investment income (other than distribution fees) and unrealized and
realized gains or losses are allocated daily to each class of shares based upon
the relative proportion of net assets of each class at the beginning of the day.
Federal Income Taxes: For federal income tax purposes, each series in the Fund
is treated as a separate taxpaying entity. It is the intent of the Series to
continue to meet the requirements of the Internal Revenue Code applicable to
regulated investment companies and to distribute all of its net income to
shareholders. For this reason and because substantially all of the Series' gross
income consists of tax-exempt interest, no federal income tax provision is
required.
Dividends and Distributions: The Series declares daily dividends from net
investment income. Payment of dividends is made monthly. Distributions of net
capital gains, if any, are made annually.
   Income distributions and capital gain distributions are determined in
accordance with income tax regulations which may differ from generally accepted
accounting principles.
                                      -9-
 <PAGE>
<PAGE>
                              
Note 2. Agreements            The Fund has a manage-
                              ment agreement with Prudential Mutual Fund
Management, Inc. (``PMF''). Pursuant to this agreement, PMF has responsibility
for all investment advisory services and supervises the subadviser's performance
of such services. PMF has entered into a subadvisory agreement with The
Prudential Investment Corporation (``PIC''); PIC furnishes investment advisory
services in connection with the management of the Fund. PMF pays for the cost of
the subadviser's services, the compensation of officers of the Fund, occupancy
and certain clerical and bookkeeping costs of the Fund. The Fund bears all other
costs and expenses.
   The management fee paid PMF is computed daily and payable monthly, at an
annual rate of .50 of 1% of the average daily net assets of the Series.
   The Fund has distribution agreements with Prudential Mutual Fund
Distributors, Inc. (``PMFD''), which acts as the distributor of the Class A
shares of the Fund, and with Prudential Securities Incorporated (``PSI''), which
acts as distributor of the Class B and Class C shares of the Fund (collectively
the ``Distributors''). The Fund compensates the Distributors for distributing
and servicing the Fund's Class A, Class B and Class C shares, pursuant to plans
of distribution, (the ``Class A, B and C Plans'') regardless of expenses
actually incurred by them. The distribution fees are accrued daily and payable
monthly.
   On July 19, 1994, shareholders of the Fund approved amendments to the Class A
and Class B distribution plans under which the distribution plans became
compensation plans, effective August 1, 1994. Prior thereto, the distribution
plans were reimbursement plans, under which PMFD and PSI were reimbursed for
expenses actually incurred by them up to the amount permitted under the Class A
and Class B Plans, respectively. The Fund is not obligated to pay any prior or
future excess distribution costs (costs incurred by the Distributors in excess
of distribution fees paid by the Fund or contingent deferred sales charges
received by the Distributors). The rate of the distribution fees charged to
Class A and Class B shares of the Fund did not change under the amended plans of
distribution. The Fund began offering Class C shares on August 1, 1994.
   Pursuant to the Class A, B and C Plans, the Fund compensates the Distributors
for distribution-related activities at an annual rate of up to .30 of 1%, .50 of
1% and 1%, of the average daily net assets of the Class A, B and C shares,
respectively. Such expenses under the Plans were .10 of 1%, .50 of 1% and .75 of
1% of the average daily net assets of the Class A, B and C shares, respectively,
for the fiscal year ended August 31, 1994.
   PMFD has advised the Series that it has received approximately $13,200 in
front-end sales charges resulting from sales of Class A shares during the fiscal
year ended August 31, 1994. From these fees, PMFD paid such sales charges to PSI
and Pruco Securities Corporation, affiliated broker-dealers, which in turn paid
commissions to salespersons and incurred other distribution costs.
   PSI has advised the Series that for the fiscal year ended August 31, 1994, it
received approximately $29,000 in contingent deferred sales charges imposed upon
certain redemptions by Class B shareholders.
   PMFD is a wholly-owned subsidiary of PMF; PSI, PMF and PIC are indirect,
wholly-owned subsidiaries of The Prudential Insurance Company of America.
                              
Note 3. Other                 Prudential Mutual Fund Ser-
Transactions                  vices, Inc. (``PMFS''), a 
with Affiliates               wholly-owned subsidiary of 
                              PMF, serves as the Fund's transfer agent. During
the year ended August 31, 1994, the Series incurred fees of approximately
$14,000 for the services of PMFS. As of August 31, 1994, approximately $1,000 of
such fees were due to PMFS. Transfer agent fees and expenses in the Statement of
Operations include certain out-of-pocket expenses paid to non-affiliates.
                              
Note 4. Portfolio             Purchases and sales of port-
Securities                    folio securities of the Series, 
                              excluding short-term investments, for the year
ended August 31, 1994 were $5,648,000 and $5,611,424, respectively.
   The cost basis of investments for federal income tax purposes at August 31,
1994 was substantially the same as the basis for financial reporting purposes
and, accordingly, net unrealized appreciation of investments for federal income
tax purposes is $630,700 (gross unrealized appreciation--$978,710, gross
unrealized depreciation--$348,010).
   At August 31, 1994, the Series sold 15 financial futures contracts on the
Municipal Bond Index expiring in September 1994. The value at disposition of
such contracts was $1,389,656. The value of such contracts on August 31, 1994
was $1,372,500, thereby resulting in an unrealized gain of $17,156.
   The Fund will elect to treat net capital losses of approximately $45,000
incurred in the ten month period ended August 31, 1994 as having been incurred
in the following fiscal year.
                                      -10-
 <PAGE>
<PAGE>
                              
Note 5. Expense               PMF has agreed to subsidize
Subsidy                       expenses so that total Series 
                              operating expenses do not exceed 1.40%, 1.80% and
2.05% of the average net assets of the Class A shares, Class B shares and Class
C shares, respectively. No subsidy was required for the year ended August 31,
1994.
                              The Series currently offers
Note 6. Capital
                              Class A, Class B and Class C shares. Class A
shares are sold with a front-end sales charge of up to 3.0%. Class B shares are
sold with a contingent deferred sales charge which declines from 5% to zero
depending on the period of time the shares are held. Class C shares are sold
with a contingent deferred sales charge of 1% during the first year. Class B
shares will automatically convert to Class A shares on a quarterly basis
approximately seven years after purchase commencing in or about February, 1995.
   The Fund has authorized an unlimited number of shares of beneficial interest
of each class at $.01 par value per share.
   Transactions in shares of beneficial interest for the fiscal years ended
August 31, 1994 and 1993 were as follows:
<TABLE>
<CAPTION>
Class A                              Shares       Amount
- ---------------------------------   --------    -----------
<S>                                 <C>         <C>
Year ended August 31, 1994:
Shares sold......................     40,971    $   479,185
Shares issued in reinvestment of
  dividends and distributions....      3,476         40,440
Shares reacquired................    (30,202)      (352,696)
                                    --------    -----------
Net increase in shares
  outstanding....................     14,245    $   166,929
                                    --------    -----------
                                    --------    -----------
Year ended August 31, 1993:
Shares sold......................     76,007    $   894,503
Shares issued in reinvestment of
  dividends and distributions....      1,747         20,330
Shares reacquired................     (1,557)       (18,441)
                                    --------    -----------
Net increase in shares
  outstanding....................     76,197    $   896,392
                                    --------    -----------
                                    --------    -----------
</TABLE>
 
<TABLE>
<CAPTION>
Class B
- ---------------------------------
<S>                                 <C>         <C>
Year ended August 31, 1994:
Shares sold......................    237,894    $ 2,782,143
Shares issued in reinvestment of
  dividends and distributions....     70,614        822,652
Shares reacquired................   (281,823)    (3,257,151)
                                    --------    -----------
Net increase in shares
  outstanding....................     26,685    $   347,644
                                    --------    -----------
                                    --------    -----------
Year ended August 31, 1993:
Shares sold......................    323,985    $ 3,805,996
Shares issued in reinvestment of
  dividends and distributions....     85,416        985,742
Shares reacquired................   (206,341)    (2,393,081)
                                    --------    -----------
Net increase in shares
  outstanding....................    203,060    $ 2,398,657
                                    --------    -----------
                                    --------    -----------
</TABLE>
 
<TABLE>
<CAPTION>
Class C
- ---------------------------------
<S>                                 <C>         <C>
August 1, 1994* through
  August 31, 1994:
Shares sold......................         18    $       200
                                    --------    -----------
                                    --------    -----------
- ---------------
* Commencement of offering of Class C shares.
</TABLE>
                                      -11-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 GEORGIA SERIES
 Financial Highlights
<TABLE>
<CAPTION>
                                                         Class A
                                  -----------------------------------------------------                    Class B
                                                                            January 22,   ------------------------------------------
                                                                            1990(D)(D)
                                        Year Ended August 31,              Through               Year Ended August 31,
                               ---------------------------------------   August 31,    ------------------------------------------
                                   1994        1993     1992     1991       1990           1994        1993      1992      1991
                               ------------   ------   ------   ------   -----------   ------------   -------   -------   -------
<S>                             <C>            <C>      <C>      <C>      <C>           <C>            <C>       <C>       <C>
PER SHARE OPERATING PERFORMANCE:
Net asset value, beginning of
  period.....................     $12.12      $11.69   $11.39   $11.05     $ 11.26       $  12.12     $ 11.69   $ 11.39   $ 11.05
                                  ------      ------   ------   ------   -----------   ------------   -------   -------   -------
Income from investment
  operations
Net investment income........        .57         .62      .65)     .64         .41            .52         .57       .61)      .60
Net realized and unrealized gain
  (loss) on investment
  transactions...............       (.76)        .85      .54      .43        (.21)          (.76)        .85       .54       .43
                                   ------      ------   ------   ------   -----------   ------------   -------   -------   -------
  Total from investment
    operations...............       (.19)       1.47     1.19     1.07         .20           (.24)       1.42      1.15      1.03
                                   ------      ------   ------   ------   -----------   ------------   -------   -------   -------
Less distributions
Dividends from net investment
  income.....................       (.57)       (.62)    (.65)    (.64)       (.41)          (.52)       (.57)     (.61)     (.60)
Distributions from net realized
  gains......................       (.17)       (.42)    (.24)    (.09)         --           (.17)       (.42)     (.24)     (.09)
                                   ------      ------   ------   ------   -----------   ------------   -------   -------   -------
  Total distributions........       (.74)      (1.04)    (.89)    (.73)       (.41)          (.69)       (.99)     (.85)     (.69)
                                   ------      ------   ------   ------   -----------   ------------   -------   -------   -------
Net asset value, end of
  period.....................     $11.19      $12.12   $11.69   $11.39     $ 11.05       $  11.19     $ 12.12   $ 11.69   $ 11.39
                                  ------      ------   ------   ------   -----------   ------------   -------   -------   -------
                                  ------      ------   ------   ------   -----------   ------------   -------   -------   -------
TOTAL RETURN#:...............      (1.58)%     13.28%   10.84%   10.03%       1.71%         (1.98)%     12.83%    10.40%     9.57%
RATIOS/SUPPLEMENTAL DATA:
Net assets, end of period
  (000)......................     $1,182      $1,107   $  177   $  102     $    83       $ 19,522     $20,811   $17,702   $17,722
Average net assets (000).....     $1,134      $  475   $  155   $   98     $    21       $ 20,492     $18,437   $17,436   $19,008
Ratios to average net assets:##
  Expenses, including
    distribution fees........       1.30%       1.27%    1.24%(D) 1.70%       1.46%*         1.70%       1.67%     1.64%(D)  2.08%
  Expenses, excluding
    distribution fees........       1.20%       1.17%    1.14%(D) 1.60%       1.36%*         1.20%       1.17%     1.14%(D)  1.58%
  Net investment income......       4.92%       5.29%    5.68%(D) 5.67%       5.92%*         4.52%       4.89%     5.28%(D)  5.36%
Portfolio turnover...........         27%         41%      58%      33%         49%            27%         41%       58%       33%

<CAPTION>
                                              Class C
                                            -----------
                                             August 1,
                                            1994(D)(D)(D)
                                              Through
                                            August 31,
                                   1990        1994
                                  -------   -----------
<S>                               <C>       <C>
PER SHARE OPERATING PERFORMANCE:
Net asset value, beginning of
  period........................  $ 11.23     $ 11.23
                                  -------   -----------
Income from investment
  operations
Net investment income...........      .65         .04
Net realized and unrealized gain
  (loss) on investment
  transactions..................     (.18)       (.04)
                                  -------   -----------
  Total from investment
    operations..................      .47          --
                                  -------   -----------
Less distributions
Dividends from net investment
  income........................     (.65)       (.04)
Distributions from net realized
  gains.........................       --          --
                                  -------   -----------
  Total distributions...........     (.65)       (.04)
                                  -------   -----------
Net asset value, end of
  period........................  $ 11.05     $ 11.19
                                  -------   -----------
                                  -------   -----------
TOTAL RETURN#:..................     4.18%      (0.06)%
RATIOS/SUPPLEMENTAL DATA:
Net assets, end of period
  (000).........................  $20,310     $   200@
Average net assets (000)........  $22,614     $   199@
Ratios to average net assets:##
  Expenses, including
    distribution fees...........     1.67%       2.05%*
  Expenses, excluding
    distribution fees...........     1.22%       1.30%*
  Net investment income.........     5.85%       4.68%*
Portfolio turnover..............       49%         27%
- ---------------


    * Annualized.
  (D) Net of expense subsidy.
(D)(D) Commencement of offering of Class A shares.
(D)(D)(D) Commencement of offering of Class C shares.
    # Total return does not consider the effects of sales loads. Total return is calculated assuming a
      purchase of shares on the first day and a sale on the last day of each period reported and includes
      reinvestment of dividends and distributions. Total returns for periods of less than a full year are not
      annualized.
   ## Because of the events referred to in (D)(D)(D) and the timing of such, the ratios for the Class C shares
      are not necessarily comparable to that of Class A and B shares and are not necessarily indicative of
      future ratios.
    @ Figures are actual and are not rounded to the nearest thousand.
</TABLE>
 
See Notes to Financial Statements.
                                      -12-
 <PAGE>
<PAGE>
                          INDEPENDENT AUDITORS' REPORT
The Shareholders and Board of Trustees
Prudential Municipal Series Fund, Georgia Series
   We have audited the accompanying statement of assets and liabilities of
Prudential Municipal Series Fund, Georgia Series, including the portfolio of
investments, as of August 31, 1994, the related statements of operations for the
year then ended and of changes in net assets for each of the two years in the
period then ended, and the financial highlights for each of the five years in
the period then ended. These financial statements and financial highlights are
the responsibility of the Fund's management. Our responsibility is to express an
opinion on these financial statements and financial highlights based on our
audits.
   We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements and financial
highlights are free of material misstatement. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements. Our procedures included confirmation of the securities owned as of
August 31, 1994 by correspondence with the custodian. An audit also includes
assessing the accounting principles used and significant estimates made by
management, as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.
   In our opinion, such financial statements and financial highlights present
fairly, in all material respects, the financial position of Prudential Municipal
Series Fund, Georgia Series, as of August 31, 1994, the results of its
operations, the changes in its net assets, and its financial highlights for the
respective stated periods in conformity with generally accepted accounting
principles.
Deloitte & Touche LLP
New York, New York
October 17, 1994

                         FEDERAL INCOME TAX INFORMATION
   We are required by the Internal Revenue Code to advise you within 60 days of
the Series' fiscal year end (August 31, 1994) as to the federal tax status of
dividends and distributions paid by the Series during such fiscal year.
Accordingly, we are advising you that in the fiscal year ended August 31, 1994,
dividends paid from net investment income of $.57 per Class A share, $.52 per
Class B share and $.04 per Class C shares were all federally tax-exempt interest
dividends. In addition, the Series paid to both Class A and B shares a long-term
capital gain distribution of $.091 per share which is taxable as such and a
short-term capital gain distribution of $.083 per share which is taxable as
ordinary income.
   In January 1995, you will be advised on IRS Form 1099 DIV or substitute 1099
DIV as to the federal tax status of the distributions received by you in
calendar year 1994.
                                      -13-

<PAGE>
These graphs are furnished to you in accordance with SEC
regulations.  They compare a $10,000 investment in Prudential
Municipal Series Fund: Georgia Series (Class A, Class B, and Class C) with a
similar investment in the Lehman Brothers Municipal Bond Index (the
Index) by portraying the initial account values at the commencement
of operations of each class and subsequent account values at the
end of each fiscal year (August 31) beginning in 1990 for Class A,
in 1984 for Class B shares and 1994 for Class C shares. For purposes of 
the graphs and, unless otherwise indicated, the accompanying tables, it has
been assumed that (a) the maximum sales charge was deducted from
the initial $10,000 investment in Class A shares; (b) the maximum
applicable contingent deferred sales charge was deducted from the
value of the investment in Class B shares and Class C shares assuming 
full redemption on August 31, 1994; (c) all recurring fees (including 
management fees) were deducted; and (d) all dividends and distributions were
reinvested. Class B shares will automatically convert to Class A shares on 
a quarterly basis approximately seven years after purchase. The conversion 
feature is expected to be implemented on or about February 1995 and is 
not reflected in the graph. The graph and accompanying tables reflect the 
past subsidy and/or waiver of expenses and/or management fees. Without 
fee waivers and expense subsidies, the value of a $10,000 investment in 
the Series and the Series' average annual total return, as 
shown above, would have been lower.

The Index is a weighted index comprised of 21,000 municipal bonds 
(general obligation bonds, revenue bonds, insured bonds and prerefunded 
bonds) selected by Lehman Brothers as representative of the long-term 
investment grade municipal bond market. 
The Index is an unmanaged index and includes the
reinvestment of all income, but does not reflect the payment of
transaction costs and advisory fees associated with an investment
in the Series.  The securities which comprise the Index may differ
substantially from the securities in the Series' portfolio because
the Index, among other things, is not state specific.  The Lehman
Brothers Municipal Bond Index is not the only index which may be used
to characterize performance of long-term, investment-grade tax-exempt
bond funds and other indexes may portray different comparative performance.

                                  -14-

<PAGE>
Trustees
Edward D. Beach
Eugene C. Dorsey
Delayne Dedrick Gold
Harry A. Jacobs, Jr.
Lawrence C. McQuade
Thomas T. Mooney
Thomas H. O'Brien
Richard A. Redeker
Nancy H. Teeters

Officers
Lawrence C. McQuade, President
Robert F. Gunia, Vice President
Susan C. Cote, Treasurer
S. Jane Rose, Secretary
Ronald Amblard, Assistant Secretary
Deborah A. Docs, Assistant Secretary

Manager
Prudential Mutual Fund Management, Inc.
One Seaport Plaza
New York, NY 10292

Investment Adviser
The Prudential Investment Corporation
Prudential Plaza
Newark, NJ 07101

Distributors
Prudential Mutual Fund Distributors, Inc.
Prudential Securities Incorporated
One Seaport Plaza
New York, NY 10292

Custodian
State Street Bank and Trust Company
One Heritage Drive
North Quincy, MA 02171

Transfer Agent
Prudential Mutual Fund Services, Inc.
P.O. Box 15005
New Brunswick, NJ 08906

Independent Accountants
Deloitte & Touche LLP
1633 Broadway
New York, NY 10019

Legal Counsel
Gardner, Carton & Douglas
Quaker Tower
321 North Clark Street
Chicago, IL 60610-4795

Prudential Mutual Funds
One Seaport Plaza
New York, NY 10292
Toll free (800) 225-1852, Collect (908) 417-7555

This report is not authorized for distribution to prospective 
investors unless preceded or accompanied by a current prospectus.

74435M309  
74435M408                           MF 113E
74435M580         (LOGO)      Cat. #6428400































<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                    Portfolio of Investments
MASSACHUSETTS SERIES                                         August 31, 1994
<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                   Value           
(Unaudited)     (000)           Description(a)        (Note 1)       
<C>           <C>          <S>                       <C>
                           LONG-TERM INVESTMENTS--97.4%
                           Boston Ind. Dev. Fin.
                             Auth., Swr. Fac. Rev.,
                             Harbor Elec. Energy
                             Co. Proj.,
Baa1             $1,500    7.375%, 5/15/15.........   $1,565,730
                           Boston Mass., Gen.
                             Oblig., Ser. A,
A*                  500(D) 9.75%, 1/1/05...........      525,325
Aaa               2,000    7.375%, 2/1/10,
                             A.M.B.A.C.............    2,254,460
                           Boston Wtr. & Swr. Comn.
                             Rev.,
A                   495(D) 7.875%, 11/1/13, Ser.
                             A.....................      539,139
A                   875    7.875%, 11/1/13, Ser.
                             A.....................      947,135
                           Brockton Mass.,
Baa1              1,030    6.125%, 6/15/18.........      997,946
                           Gloucester Mass.,
                             Gen. Oblig.,
Aaa               2,000    5.50%, 11/15/13,
                             F.S.A.................    1,871,520
                           Holyoke, Gen. Oblig.,
                             Sch. Proj.,
Aaa                 700    8.10%, 6/15/05,
                             M.B.I.A...............      824,768
                           Lowell, Gen. Oblig.,
Baa1                750(D) 7.625%, 2/15/10.........      870,180
                           Lynn Wtr. & Swr. Comn.,
                             Gen. Rev., Ser. A,
Aaa               2,100(D) 7.25%, 12/1/10,
                             M.B.I.A...............    2,382,786
                           Mass. Bay Trans. Auth.,
A                 1,500    6.20%, 3/1/16, Ser. B...    1,508,865
                           Mass. St. Gen. Oblig.,
A                   665    Zero Coupon, 8/1/06,
                             Ser. A................      340,360
                           Mass. St. Hlth. & Edl.
                             Facs. Auth. Rev.,
                             Gen. Oblig.,
Aaa               1,500    6.00%, 8/1/09, Ser. C,
                           F.G.I.C.................    1,518,345
                           Bentley Coll.,
A                 1,325(D) 8.125%, 7/1/17, Ser.
                             G.....................    1,392,853
                           Beth Israel Hosp.,
Aaa               1,500(D)(D) 8.472%, 7/1/25,
                             A.M.B.A.C.............    1,425,000
                           Beverly Hosp., Ser. D,
Aaa                 750    7.30%, 7/1/13,
                             M.B.I.A...............      828,173
                           Holy Cross Coll.,
A1                1,500(D) 8.35%, 11/1/07, Ser.
                             F.....................    1,570,740
                           Mass. St. Hlth. & Edl.
                             Facs. Auth. Rev.,
                           Holyoke Hosp. Rev.,
Baa1             $1,000    6.50%, 7/1/15...........     $958,670
                           Jordan Hosp.,
A-*               1,650    6.875%, 10/1/22.........    1,628,633
                           Lahey Clinic, Ser. B,
Aaa               1,250    5.375%, 7/1/23,
                             M.B.I.A...............    1,092,550
                           New England Med. Ctr.,
A1                1,175    7.875%, 7/1/11, Ser.
                             E.....................    1,317,856
                           6.875%, 4/1/22, Ser. D,
Aaa               1,000    A.M.B.A.C...............    1,052,570
                           Newton-Wellesley Hosp.,
Aaa               2,000    8.00%, 7/1/18, Ser. C,
                             B.I.G.................    2,234,620
                           Northeastern Univ., Ser.
                             D,
Aaa               1,500    7.125%, 10/1/10,
                             A.M.B.A.C.............    1,629,780
                           St. Elizabeth Hosp.,
AA*               1,200(D) 7.75%, 8/1/27, Ser. B,
                             F.H.A.................    1,322,676
                           Tufts Univ.,
Aaa               1,235(D) 7.40%, 8/1/18, Ser. C...    1,370,726
A1                  265    7.40%, 8/1/18, Ser. C...      284,364
                           Valley Regl. Hlth. Sys.,
AAA*                825    7.00%, 7/1/10...........      891,734
Baa               1,000(D) 8.00%, 7/1/18, Ser. B...    1,165,060
                           Mass. St. Hsg. Fin.
                             Agcy. Hsg. Rev.,
                             Insured Rental, Ser.
                             A,
Aaa               1,000    6.65%, 7/1/19,
                             A.M.B.A.C.............    1,008,840
                           Sngl. Fam. Mtge.,
Aa                1,755    8.10%, 12/1/14, Ser.
                             6.....................    1,878,692
Aa                  415    9.50%, 12/1/16, Ser.
                             1985A.................      433,256
Aa                  985    7.125%, 6/1/25, Ser.
                             21....................    1,001,075
                           Mass. St. Ind. Fin.
                             Agcy. Rev., Brooks
                             Sch.,
A                   640    5.95%, 7/1/23...........      611,949
                           Cape Cod Hlth. Sys.,
Aaa               2,000(D) 8.50%, 11/15/20.........    2,393,960
                           Merrimack College,
BBB-*               990    7.125%, 7/1/12..........    1,016,948
                           Springfield College,
Baa1                900    5.625%, 9/15/10.........      838,341
</TABLE>
 
                                      -5-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                    
MASSACHUSETTS SERIES                                         
<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                   Value           
(Unaudited)     (000)           Description(a)        (Note 1)       
<C>           <C>          <S>                       <C>
                           Mass. St. Indl. Fin.
                             Agcy.,
                             Poll. Ctrl. Rev.,
                             Eastern Edison Co.
                             Project,
Baa              $1,000    5.875%, 8/1/08..........     $947,630
                           Mass. St. Mun. Wholesale Elec.
                             Co. Pwr. Supply Sys. Rev.,
A                   525(D) 6.75%, 7/1/17, Ser. B...      584,503
A                   225    6.75%, 7/1/17, Ser. B...      231,980
                           Mass. St. Port. Auth.
                             Rev.,
Aa                  260    9.375%, 7/1/15, Ser.
                             B.....................      276,011
                           Mass. St. Tpke. Auth.
                             Rev.,
Aaa                 450    5.125%, 1/1/23, Ser. A,
                           F.G.I.C.................      381,551
                           Mass. St. Wtr. Res.
                             Auth.,
A                   800    5.75%, 12/1/21, Ser.
                             A,....................      739,040
                           Palmer, Gen. Oblig.,
                             Ser. F,
Aaa                 500(D) 7.30%, 3/1/10,
                             A.M.B.A.C.............      563,100
                           Plymouth Cnty. Corr. Facs. Proj.,
                             Cert. of Part.,
A-*                 500    7.00%, 4/1/22, Ser. A...      521,240
                           Puerto Rico Aqueduct &
                             Swr. Auth. Rev.,
Aaa                 400    10.25%, 7/1/09,
                             E.T.M.................      552,700
                           Puerto Rico Comnwlth.,
                             Gen. Oblig.,
Aaa                 250    7.00%, 7/1/10,
                             M.B.I.A...............      280,498
Aaa                 750    7.00%, 7/1/10,
                             A.M.B.A.C.............      841,492
Aaa               1,250 D)(D) 8.393%, 7/1/20,
                             F.S.A.................    1,171,875
                           Puerto Rico Elec. Pwr.
                             Auth. Rev.,
Baa1                450    7.00%, 7/1/06, Ser. S...      503,510
                           Puerto Rico Hsg. Fin.
                             Corp.,
                             Bank & Fin. Agcy.,
Baa                 750    5.125%, 12/1/05.........      703,215
                           Puerto Rico Pub. Bldgs.
                             Auth.,
                             Pub. Ed. & Hlth.
                             Facs.,
Baa1             $1,000    5.50%, 7/1/21, Ser. M...     $894,580
                           Virgin Islands Pub. Fin.
                             Auth. Rev.,
                             Hwy. Trans. Trust
                             Fund,
NR                  400    7.25%, 10/1/18, Ser.
                             A.....................      412,648
                           Virgin Islands Wtr. & Pwr. Auth.,
                             Wtr. Sys. Rev.,
NR                1,000    8.50%, 1/1/10, Ser. A...    1,098,560
                                                     -----------
                           Total long-term
                             investments
                           (cost $53,236,506)......   56,199,758
                                                     -----------
                           Total Investments--97.4%
                           (cost $53,236,506; Note
                             4)....................   56,199,758
                           Other assets in excess
                             of
                             liabilities--2.6%.....    1,513,488
                                                     -----------
                           Net Assets--100%........  $57,713,246
                                                     -----------
                                                     -----------
</TABLE>
 
- ------------------
(a) The following abbreviations are used in portfolio descriptions:
    A.M.B.A.C.--American Municipal Bond Assurance
    Corporation.
    B.I.G.--Bond Investors Guaranty Insurance Company.
    E.T.M.--Escrowed to Maturity.
    F.G.I.C.--Financial Guaranty Insurance Association.
    F.H.A.--Federal Housing Administration.
    F.S.A.--Financial Security Assurance.
    M.B.I.A.--Municipal Bond Insurance Association.
          * Standard & Poor's rating.
        (D) Prerefunded issues are secured by escrowed cash
            and direct U.S. guaranteed obligations.
     (D)(D) Inverse floating rate bond. The coupon is
            inversely indexed to a floating interest rate.
            The rate shown is the rate at period end.
 
NR--Not Rated by Moody's or Standard & Poor's.
The Fund's current Statement of Additional Information contains a description of
Moody's and Standard & Poor's ratings.
                                      -6-     See Notes to Financial Statements.

<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 MASSACHUSETTS SERIES
 Statement of Assets and Liabilities
<TABLE>
<CAPTION>
Assets                                                                                      August 31, 1994
                                                                                            ---------------
<S>                                                                                         <C>
Investments, at value (cost $53,236,506).................................................     $56,199,758
Receivable for investments sold..........................................................       3,075,712
Interest receivable......................................................................         883,072
Receivable for Fund shares sold..........................................................          23,672
Deferred expenses and other assets.......................................................           1,856
                                                                                            ---------------
  Total assets...........................................................................      60,184,070
                                                                                            ---------------
Liabilities
Bank overdraft...........................................................................       1,124,591
Payable for investments purchased........................................................       1,008,251
Payable for Fund shares reacquired.......................................................         184,769
Accrued expenses.........................................................................          52,888
Dividends payable........................................................................          50,545
Due to Manager...........................................................................          24,793
Due to Distributors......................................................................          23,977
Deferred trustees' fees..................................................................           1,010
                                                                                            ---------------
  Total liabilities......................................................................       2,470,824
                                                                                            ---------------
Net Assets...............................................................................     $57,713,246
                                                                                            ---------------
                                                                                            ---------------
Net assets were comprised of:
  Shares of beneficial interest, at par..................................................     $    50,786
  Paid-in capital in excess of par.......................................................      55,123,101
                                                                                            ---------------
                                                                                               55,173,887
  Accumulated net realized loss on investments...........................................        (423,893)
  Net unrealized appreciation on investments.............................................       2,963,252
                                                                                            ---------------
  Net assets, August 31, 1994............................................................     $57,713,246
                                                                                            ---------------
                                                                                            ---------------
Class A:
  Net asset value and redemption price per share ($2,293,090 / 201,670 shares of
    beneficial interest
    issued and outstanding)..............................................................          $11.37
  Maximum sales charge (3% of offering price)............................................             .35
                                                                                            ---------------
  Maximum offering price to public.......................................................          $11.72
                                                                                            ---------------
                                                                                            ---------------
Class B:
  Net asset value, offering price and redemption price per share ($55,419,940 / 4,876,964
    shares of
    beneficial interest issued and outstanding)..........................................          $11.36
                                                                                            ---------------
                                                                                            ---------------
Class C:
  Net asset value, offering price and redemption price per share ($216.46 / 19.05 shares
    of
    beneficial interest issued and outstanding)..........................................          $11.36
                                                                                            ---------------
                                                                                            ---------------
</TABLE>
 
See Notes to Financial Statements.
                                      -7-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 MASSACHUSETTS SERIES
 Statement of Operations
<TABLE>
<CAPTION>
                                         Year Ended
                                         August 31,
Net Investment Income                       1994
                                         -----------
<S>                                      <C>
Income
  Interest............................   $ 4,022,765
                                         -----------
Expenses
  Management fee......................       310,614
  Distribution fee--Class A...........         2,578
  Distribution fee--Class B...........       297,719
  Custodian's fees and expenses.......        80,500
  Transfer agent's fees and
  expenses............................        32,000
  Registration fees...................        20,500
  Legal fees..........................        15,000
  Audit fee...........................        10,500
  Reports to shareholders.............         8,000
  Trustees' fees......................         3,375
  Miscellaneous.......................         1,014
                                         -----------
    Total expenses....................       781,800
                                         -----------
Net investment income.................     3,240,965
                                         -----------
Realized and Unrealized
Gain (Loss) on Investments
Net realized loss on:
  Investment transactions.............      (195,709)
  Financial futures contract
  transactions........................       (66,531)
                                         -----------
                                            (262,240)
                                         -----------
Net change in unrealized
  appreciation/depreciation on:
  Investments.........................    (3,709,011)
  Financial futures contracts.........        61,875
                                         -----------
                                          (3,647,136)
                                         -----------
Net loss on investments...............    (3,909,376)
                                         -----------
Net Decrease in Net Assets
Resulting from Operations.............   $  (668,411)
                                         -----------
                                         -----------
</TABLE>
 
 PRUDENTIAL MUNICIPAL SERIES FUND
 MASSACHUSETTS SERIES
 Statement of Changes in Net Assets
<TABLE>
<CAPTION>
                                Year Ended August 31,
Increase (Decrease) in       ---------------------------
  Net Assets                     1994           1993
                             ------------    -----------
<S>                          <C>             <C>
Operations
  Net investment income....  $  3,240,965    $ 3,093,949
  Net realized gain (loss)
    on investment
    transactions...........      (262,240)     1,042,349
  Net change in unrealized
  appreciation/depreciation
    of investments.........    (3,647,136)     2,273,453
                             ------------    -----------
  Net increase (decrease)
    in net assets resulting
    from operations........      (668,411)     6,409,751
                             ------------    -----------
Dividends and distributions (Note 1):
  Dividends from net
    investment income
    Class A................      (144,412)       (76,855)
    Class B................    (3,096,493)    (3,017,094)
    Class C................           (60)            --
                             ------------    -----------
                               (3,240,965)    (3,093,949)
                             ------------    -----------
  Distributions from net
    realized gains
    Class A................       (16,934)            --
    Class B................      (376,754)            --
                             ------------    -----------
                                 (393,688)            --
                             ------------    -----------
Series share transactions
  (Note 5)
  Net proceeds from shares
    sold...................     7,355,596     10,228,873
  Net asset value of shares
    issued in reinvestment
    of dividends...........     2,173,313      1,821,686
  Cost of shares
  reacquired...............   (10,958,113)    (6,272,800)
                             ------------    -----------
  Net increase (decrease)
    in net assets from
    Series share
    transactions...........    (1,429,204)     5,777,759
                             ------------    -----------
Total increase
  (decrease)...............    (5,732,268)     9,093,561
Net Assets
Beginning of year..........    63,445,514     54,351,953
                             ------------    -----------
End of year................  $ 57,713,246    $63,445,514
                             ------------    -----------
                             ------------    -----------
</TABLE>
 
See Notes to Financial Statements.        See Notes to Financial Statements.
                                      -8-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 MASSACHUSETTS SERIES
 Notes to Financial Statements
   Prudential Municipal Series Fund (the ``Fund'') is registered under the
Investment Company Act of 1940, as an open-end investment company. The Fund was
organized as a Massachusetts business trust on May 18, 1984 and consists of
seventeen series. The monies of each series are invested in separate,
independently managed portfolios. The Massachusetts Series (the ``Series'')
commenced investment operations in September, 1984. The Series is diversified
and seeks to achieve its investment objective of obtaining the maximum amount of
income exempt from federal and applicable state income taxes with the minimum of
risk by investing in ``investment grade'' tax-exempt securities whose ratings
are within the four highest ratings categories by a nationally recognized
statistical rating organization or, if not rated, are of comparable quality. The
ability of the issuers of the securities held by the Series to meet their
obligations may be affected by economic developments in a specific state,
industry or region.
                              
Note 1. Accounting            The following is a summary
Policies                      of significant accounting poli-
                              cies followed by the Fund, and the Series, in the
preparation of its financial statements.
Securities Valuations: The Fund values municipal securities (including
commitments to purchase such securities on a ``when-issued'' basis) on the basis
of prices provided by a pricing service which uses information with respect to
transactions in bonds, quotations from bond dealers, market transactions in
comparable securities and various relationships between securities in
determining values. If market quotations are not readily available from such
pricing service, a security is valued at its fair value as determined under
procedures established by the Trustees.
   Short-term securities which mature in more than 60 days are valued at current
market quotations. Short-term securities which mature in 60 days or less are
valued at amortized cost which approximates market value.
   All securities are valued as of 4:15 P.M., New York time.
Financial Futures Contracts: A financial futures contract is an agreement to
purchase (long) or sell (short) an agreed amount of debt securities at a set
price for delivery on a future date. Upon entering into a financial futures
contract, the Series is required to pledge to the broker an amount of cash
and/or other assets equal to a certain percentage of the contract amount. This
amount is known as the ``initial margin''. Subsequent payments, known as
``variation margin'', are made or received by the Series each day, depending on
the daily fluctuations in the value of the underlying security. Such variation
margin is recorded for financial statement purposes on a daily basis as
unrealized gain or loss. The Series invests in financial futures contracts
solely for the purpose of hedging its existing portfolio securities or
securities the Series intends to purchase against fluctuations in value caused
by changes in prevailing market interest rates. Should interest rates move
unexpectedly, the Series may not achieve the anticipated benefits of the
financial futures contracts and may realize a loss. The use of futures
transactions involves the risk of imperfect correlation in movements in the
price of futures contracts, interest rates and the underlying hedged assets.
Securities Transactions and Investment Income: Securities transactions are
recorded on the trade date. Realized gains and losses on sales of securities are
calculated on the identified cost basis. Interest income is recorded on the
accrual basis. The Series amortizes premiums and original issue discount paid on
purchases of portfolio securities as adjustments to interest income.
   Net investment income (other than distribution fees) and unrealized and
realized gains or losses are allocated daily to each class of shares based upon
the relative proportion of net assets of each class at the beginning of the day.
Federal Income Taxes: For federal income tax purposes, each series in the Fund
is treated as a separate taxpaying entity. It is the intent of the Series to
continue to meet the requirements of the Internal Revenue Code applicable to
regulated investment companies and to distribute all of its net income to
shareholders. For this reason and because substantially all of the Series' gross
income consists of tax-exempt interest, no federal income tax provision is
required.
Dividends and Distributions: The Series declares daily dividends from net
investment income. Payment of dividends is made monthly. Distributions of net
capital gains, if any, are made annually.
   Income distributions and capital gain distributions are determined in
accordance with income tax regulations which may differ from generally accepted
accounting principles. These differences are primarily due to differing
treatments for short-term capital gains and market discount.
                                      -9-
 <PAGE>
<PAGE>
                              
Note 2. Agreements            The Fund has a management
                              agreement with Prudential Mutual Fund Management,
Inc. (``PMF''). Pursuant to this agreement, PMF has responsibility for all
investment advisory services and supervises the subadviser's performance of such
services. PMF has entered into a subadvisory agreement with The Prudential
Investment Corporation (``PIC''). PIC furnishes investment advisory services in
connection with the management of the Fund. PMF pays for the cost of the
subadviser's services, the compensation of officers of the Fund, occupancy and
certain clerical and bookkeeping costs of the Fund. The Fund bears all other
costs and expenses.
   The management fee paid PMF is computed daily and payable monthly, at an
annual rate of .50 of 1% of the average daily net assets of the Series.
   The Fund has distribution agreements with Prudential Mutual Fund
Distributors, Inc. (``PMFD''), which acts as the distributor of the Class A
shares of the Fund, and with Prudential Securities Incorporated (``PSI''), which
acts as distributor of the Class B and Class C shares of the Fund (collectively
the ``Distributors''). The Fund compensates the Distributors for distributing
and servicing the Fund's Class A, Class B and Class C shares, pursuant to plans
of distribution, (the ``Class A, B and C Plans'') regardless of expenses
actually incurred by them. The distribution fees are accrued daily and payable
monthly.
   On July 19, 1994, shareholders of the Fund approved amendments to the Class A
and Class B distribution plans under which the distribution plans became
compensation plans, effective August 1, 1994. Prior thereto, the distribution
plans were reimbursement plans, under which PMFD and PSI were reimbursed for
expenses actually incurred by them up to the amount permitted under the Class A
and Class B Plans, respectively. The Fund is not obligated to pay any prior or
future excess distribution costs (costs incurred by the Distributors in excess
of distribution fees paid by the Fund or contingent deferred sales charges
received by the Distributors). The rate of the distribution fees charged to
Class A and Class B shares of the Fund did not change under the amended plans of
distribution. The Fund began offering Class C shares on August 1, 1994.
   Pursuant to the Class A, B and C Plans, the Fund compensates the Distributors
for distribution-related activities at an annual rate of up to .30 of 1%, .50 of
1% and 1%, of the average daily net assets of the Class A, B and C shares,
respectively. Such expenses under the Plans were .10 of 1%, .50 of 1% and .75 of
1% of the average daily net assets of the Class A, B and C shares, respectively,
for the fiscal year ended August 31, 1994.
   PMFD has advised the Series that it has received approximately $35,100 in
front-end sales charges resulting from sales of Class A shares during the fiscal
year ended August 31, 1994. From these fees, PMFD paid such sales charges to PSI
and Pruco Securities Corporation, affiliated broker-dealers, which in turn paid
commissions to salespersons and incurred other distribution costs.
   PSI has advised the Series that for the fiscal year ended August 31, 1994, it
received approximately $89,800 in contingent deferred sales charges imposed upon
certain redemptions by Class B shareholders.
   PMFD is a wholly-owned subsidiary of PMF; PSI, PMF and PIC are indirect,
wholly-owned subsidiaries of The Prudential Insurance Company of America.
                              
Note 3. Other                 Prudential Mutual Fund Ser-
Transactions                  vices, Inc. (``PMFS''), a 
With Affiliates               wholly-owned subsidiary of 
                              PMF, serves as the Fund's transfer agent and
during the year ended August 31, 1994, the Series incurred fees of approximately
$27,000 for the services of PMFS. As of August 31, 1994, approximately $2,200 of
such fees were due to PMFS. Transfer agent fees and expenses in the statement of
operations include certain out-of-pocket expenses paid to non-affiliates.
                              
Note 4. Portfolio             Purchases and sales of port-
Securities                    folio securities of the Series, 
                              excluding short-term investments, for the year
ended August 31, 1994 were $19,829,440 and $21,559,342, respectively.
   The cost basis of investments for federal income tax purposes was
substantially the same as for financial reporting purposes and, accordingly, at
August 31, 1994, net unrealized appreciation of investments, including
short-term investments for federal income tax purposes was $2,963,252 (gross
unrealized appreciation--$3,554,736, gross unrealized depreciation--$591,484).
   The Fund will elect to treat net capital losses of approximately $305,000
incurred in the four month period ended August 31, 1994 as having been incurred
in the following fiscal year.
                              
Note 5. Capital               The Series currently offers
                              Class A, Class B and Class C shares. Class A
shares are sold with a front-end sales charge of up to 3.0%. Class B shares are
sold with a contingent deferred sales charge which declines from 5% to zero
depending on the period of time the shares are held. Class C shares are sold
with a contingent deferred sales charge of 1%
                                      -10-
 <PAGE>
<PAGE>
during the first year. Class B shares will automatically convert to Class A
shares on a quarterly basis approximately seven years after purchase commencing
on or about February 1995.
   The Fund has authorized an unlimited number of shares of beneficial interest
of each class at $.01 par value per share.
   Transactions in shares of beneficial interest for the fiscal years ended
August 31, 1994 and 1993 were as follows:
<TABLE>
<CAPTION>
Class A                                 Shares          Amount
- ---------------------------------   --------------    -----------
<S>                                 <C>               <C>
Year ended August 31, 1994:
Shares sold......................           79,658    $   955,193
Shares issued in reinvestment of
  dividends and distributions....            7,338         86,177
Shares reacquired................          (76,352)      (888,834)
                                    --------------    -----------
Net increase in shares
  outstanding....................           10,644    $   152,536
                                    --------------    -----------
                                    --------------    -----------
Year ended August 31, 1993:
Shares sold......................          117,227    $ 1,391,818
Shares issued in reinvestment of
  dividends......................            3,409         40,192
Shares reacquired................           (8,122)       (95,498)
                                    --------------    -----------
Net increase in shares
  outstanding....................          112,514    $ 1,336,512
                                    --------------    -----------
                                    --------------    -----------
</TABLE>
 
<TABLE>
<CAPTION>
Class B                                 Shares          Amount
- ---------------------------------   --------------    -----------
<S>                                 <C>               <C>
Year ended August 31, 1994:
Shares sold......................          533,589    $ 6,293,496
Shares issued in reinvestment of
  dividends and distributions....          177,548      2,087,119
Shares reacquired................         (857,454)    (9,963,041)
                                    --------------    -----------
Net decrease in shares
  outstanding....................         (146,317)   $(1,582,426)
                                    --------------    -----------
                                    --------------    -----------
Year ended August 31, 1993:
Shares sold......................          750,946    $ 8,837,055
Shares issued in reinvestment of
  dividends......................          151,724      1,781,494
Shares reacquired................         (529,282)    (6,177,302)
                                    --------------    -----------
Net decrease in shares
  outstanding....................          373,388    $ 4,441,247
                                    --------------    -----------
                                    --------------    -----------
</TABLE>
 
<TABLE>
<CAPTION>
Class C
- ---------------------------------
<S>                                 <C>               <C>
August 1, 1994* through
  August 31, 1994:
Shares sold......................            9,403    $   106,907
Shares issued in reinvestment of
  dividends......................                1             17
Shares reacquired................           (9,385)      (106,238)
                                    --------------    -----------
Net increase in shares
  outstanding....................               19    $       686
                                    --------------    -----------
                                    --------------    -----------
- ---------------
* Commencement of offering of Class C shares.
</TABLE>
                                      -11-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 MASSACHUSETTS SERIES
 Financial Highlights
<TABLE>
<CAPTION>
                             Class A                                                                                    Class C
     -------------------------------------------------------                         Class B                          -----------
                                                 January 22,   ----------------------------------------------------    August 1,
                                                   1990(D)                                                            1994(D)(D)
               Year Ended August 31,               through                    Year Ended August 31,                     through
     -----------------------------------------   August 31,    ----------------------------------------------------   August 31,
         1994        1993      1992      1991       1990         1994       1993       1992       1991       1990        1994
     ------------   -------   -------   ------   -----------   --------   --------   --------   --------   --------   -----------
<S>  <C>            <C>       <C>       <C>      <C>           <C>        <C>        <C>        <C>        <C>        <C>
PER
SHARE
OPERATING
  PERFORMANCE:
Net
asset
value,
beginning
  of
 period.. $12.17    $ 11.50   $ 10.94   $10.44     $ 10.70     $ 12.17    $  11.49   $  10.94   $  10.44   $  10.74     $ 11.41
     ------------   -------   -------   ------   -----------   --------   --------   --------   --------   --------   -----------
Income
  from
  investment
  operations
Net
investment
 income...   .67        .68       .69      .70         .41         .61         .63        .64        .65        .65         .04
Net
realized
  and
  unrealized
  gain
  (loss)
  on
  investment
  trans-
  actions.. (.73)       .67       .56      .50        (.26)       (.74)        .68        .55        .50       (.30)       (.05)
     ------------   -------   -------   ------   -----------   --------   --------   --------   --------   --------   -----------
  Total
   from
   invest-
   ment
   oper-
   ations.. (.06)      1.35      1.25     1.20         .15        (.13)       1.31       1.19       1.15        .35        (.01)
     ------------   -------   -------   ------   -----------   --------   --------   --------   --------   --------   -----------
Less
distributions
Dividends
  from
  net
  investment
  income..  (.67)      (.68)     (.69)    (.70)       (.41)       (.61)       (.63)      (.64)      (.65)      (.65)       (.04)
Distributions
  from net
  realized
  gains..   (.07)       --        --       --          --         (.07)         --         --         --         --          --
     ------------   -------   -------   ------   -----------   --------   --------   --------   --------   --------   -----------
  Total
  distri-
  butions.. (.74)      (.68)     (.69)    (.70)       (.41)       (.68)       (.63)      (.64)      (.65)      (.65)       (.04)
     ------------   -------   -------   ------   -----------   --------   --------   --------   --------   --------   -----------
Net
asset
value,
  end
  of
  period.  $11.37   $ 12.17   $ 11.50   $10.94     $ 10.44     $ 11.36    $  12.17   $  11.49   $  10.94   $  10.44     $ 11.36
     ------------   -------   -------   ------   -----------   --------   --------   --------   --------   --------   -----------
     ------------   -------   -------   ------   -----------   --------   --------   --------   --------   --------   -----------
TOTAL
RETURN#:.   (.58)%    12.10%    11.76%   11.81%       1.41%      (1.15)%     11.77%     11.23%     11.38%      3.40%      (0.27)%
RATIOS/SUPPLEMENTAL
  DATA:
Net
assets,
  end
  of
 period
 (000)..  $2,293    $ 2,325   $   903   $  665     $   257     $55,420    $ 61,121   $ 53,449   $ 49,641   $ 50,575     $   216@
Average
  net
 assets
 (000)..  $2,578    $ 1,336   $   770   $  344     $   127     $59,544    $ 55,965   $ 50,607   $ 49,083   $ 52,974     $    15
Ratios
  to
  average
  net
assets:##
  Expenses,
  including
    distri-
    bution
    fees...  .87%       .95%      .99%    1.05%       1.04%*      1.27%       1.35%      1.39%      1.45%      1.37%       1.57%*
  Expenses,
  excluding
    distri-
    bution
    fees...  .77%       .85%      .89%     .95%        .95%*       .77%        .85%       .89%       .95%       .90%        .82%*
Net
investment
 income...  5.60%      5.79%     6.14%    6.53%       6.60%*      5.20%       5.39%      5.74%      6.13%      6.21%       5.06%*
Portfolio
turnover...   33%        56%       32%      34%         33%         33%         56%        32%        34%        33%         33%
 
- ---------------
   * Annualized.
 (D) Commencement of offering of Class A shares.
(D)(D) Commencement of offering of Class C shares.
   # Total return does not consider the effects of sales loads. Total return is calculated assuming a purchase of shares on
     the first day and a sale on the last day of each period reported and includes reinvestment of dividends and
     distributions. Total returns for periods of less than a full year are not annualized.
  ## Because of the events referred to in (D)(D) and the timing of such, the ratios for the Class C shares are not
     necessarily comparable to that of Class A or B shares and are not necessarily indicative of future ratios.
   @ Figures are actual and not rounded to the nearest thousand.
</TABLE>
 
See Notes to Financial Statements.
                                      -12-

<PAGE>
                          INDEPENDENT AUDITORS' REPORT
The Shareholders and Board of Trustees
Prudential Municipal Series Fund, Massachusetts Series
   We have audited the accompanying statement of assets and liabilities of
Prudential Municipal Series Fund, Massachusetts Series, including the portfolio
of investments, as of August 31, 1994, the related statements of operations for
the year then ended and of changes in net assets for each of the two years in
the period then ended, and the financial highlights for each of the five years
in the period then ended. These financial statements and financial highlights
are the responsibility of the Fund's management. Our responsibility is to
express an opinion on these financial statements and financial highlights based
on our audits.
   We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements and financial
highlights are free of material misstatement. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements. Our procedures included confirmation of the securities owned as of
August 31, 1994 by correspondence with the custodian. An audit also includes
assessing the accounting principles used and significant estimates made by
management, as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.
   In our opinion, such financial statements and financial highlights present
fairly, in all material respects, the financial position of Prudential Municipal
Series Fund, Massachusetts Series, as of August 31, 1994, the results of its
operations, the changes in its net assets, and its financial highlights for the
respective stated periods in conformity with generally accepted accounting
principles.
Deloitte & Touche LLP
New York, New York
October 17, 1994
                         FEDERAL INCOME TAX INFORMATION
   We are required by the Internal Revenue Code to advise you within 60 days of
the Series' fiscal year end (August 31, 1994) as to the federal tax status of
dividends paid by the Series during such fiscal year. Accordingly, we are
advising you that in the fiscal year ended August 31, 1994, dividends paid from
net investment income of $.67 per Class A share, $.61 per Class B share, and
$.04 per Class C shares were all federally tax-exempt interest dividends. In
addition, the Series paid to both Class A and Class B shares a long-term capital
gain distribution of $.053 per share which is taxable as such and a short-term
capital gain distribution of $.021 which is taxable as ordinary income.
   In January 1995, you will be advised on IRS Form 1099 DIV or substitute 1099
DIV as to the federal tax status of the distributions received by you in
calendar year 1994.
                                      -13-
 <PAGE>
<PAGE>
   These graphs are furnished to you in accordance with SEC regulations. They
compare a $10,000 investment in Prudential Municipal Series Fund: Massachusetts
Series (Class A, Class B, and Class C) with a similar investment in the Lehman
Brothers Municipal Bond Index (the Index) by portraying the initial account
values at the commencement of operations of each class and subsequent account
values at the end of each fiscal year (August 31) beginning in 1990 for Class A,
in 1984 for Class B shares and 1994 for Class C shares. For purposes of the
graphs and, unless otherwise indicated, the accompanying tables, it has been
assumed that (a) the maximum sales charge was deducted from the initial $10,000
investment in Class A shares; (b) the maximum applicable contingent deferred
sales charge was deducted from the value of the investment in Class B shares and
Class C shares, assuming full redemption on August 31, 1994; (c) all recurring
fees (including management fees) were deducted; and (d) all dividends and
distributions were reinvested. Class B shares will automatically convert to
Class A shares on a quarterly basis approximately seven years after purchase.
This conversion feature is expected to be implemented on or about February 1995
and is not reflected in the graph. The graph and accompanying tables reflect the
past subsidy and/or waiver of expenses and/or management fees. Without fee
waivers and expense subsidies, the value of a $10,000 investment in the Series
and the Series' average annual total return, as shown above, would have been
lower.
   The Index is a weighted index comprised of 21,000 municipal bonds (general
obligation bonds, revenue bonds, insured bonds and prerefunded bonds) selected
by Lehman Brothers as representative of the long-term investment grade municipal
bond market. The Index is an unmanaged index and includes the reinvestment of
all income, but does not reflect the payment of transaction costs and advisory
fees associated with an investment in the Series. The securities which comprise
the Index may differ substantially from the securities in the Series' portfolio
because the Index, among other things, is not state specific. The Lehman
Brothers Municipal Bond Index is not the only index which may be used to
characterize performance of long-term, investment-grade tax-exempt bond funds
and other indexes may portray different comparative performance.
                                      -14-
 




























<PAGE>

A N N U A L  R E P O R T              August 31, 1994

  Prudential
   Municipal
  Series Fund

    (ICON)

  Massachusetts
Money Market Series



   (LOGO)

<PAGE>

                    Letter to
                    Shareholders
                    -----------------------------------------------------------
                                                               October 18, 1994

Dear Shareholder:

   Short-term interest rates moved steadily higher during the last 12 months,
accelerating in 1994 as the Federal Reserve boosted short-term interest rates 
in hopes of preventing inflation from increasing as the economy began to expand
rapidly.  As a result, your Prudential Municipal Series Fund Massachusetts 
Money Market Series -- produced higher yields than six months ago.

<TABLE>
                               SERIES PERFORMANCE
                              As of August 31, 1994
<CAPTION>
Net Asset    Weighted       7-Day        Taxable Equivalent Yield     Net
 Value       Avg. Mat.  Current Yield    @28%     @31%     @39.6%  Asset (Mil.)
<S>          <C>        <C>              <C>      <C>      <C>     <C>
$1.00        57 days        2.28%        3.6%     3.8%       4.3%      $37.3
</TABLE>

   Past performance is no guarantee of future results

   Please note than an investment in the Series is neither insured nor
guaranteed by the  U. S. government, and there can be no assurance that the
Series will be able to maintain a stable net asset value of $1.00 per share.

   The Massachusetts Money Market Series seeks to provide the highest level of
state and federally tax-exempt current income consistent with the preservation
of principal and liquidity.  Interest on municipal obligations may be subject 
to the federal alternative minimum tax.  The Series invests primarily in 
high-quality, short-term, tax-exempt obligations issued by the state, 
municipalities, and authorities.  During the year, the Series' credit quality 
remained consistently high, with 100% of  its holdings rated in the highest 
category as determined by Moody's Investor Service or Standard & Poor's, or if
unrated, deemed to be of comparable quality by the adviser.

In 1994, Rates Rose Rapidly

   Short-term taxable interest rates were relatively stable until February, 
when the Federal Reserve, concerned that the rapidly expanding economy could 
ignite inflation, started to increase the fed funds rate (the overnight 
interbank lending rate).  If the economy grows too quickly, shortages develop 

Municipal Market Is Different

   While the fed funds rate spiked 175 basis points (100 basis points is one 
percentage point), the yields of tax-free securities did not increase by a 
simi-
                                  -1-

<PAGE>

lar margin. While this rising interest rate activity in the taxable market 
does affect the tax-free market, the impact generally lags. The short-term 
municipal market is also more influenced by seasonal supply and demand factors 
than  taxable Treasury bills.

   Rising rates in the taxable market can be followed by higher yields in the 
tax-free market. Anticipating the Fed would raise interest rates in February, 
we maintained a shorter weighted average maturity so that we could take 
advantage of higher rates as they became available.  Once the Fed moved, we 
selectively extended the maturity of the portfolio. Generally, our weighted 
average maturity was shorter than that of our peers.

Massachusetts: Jobs on the  Rebound

   Although Massachusetts was hurt far more so than any other state by the last
recession,  job creation is now on the rebound, primarily in construction, 
business services, computer software, health care, management and consulting. 
The mutual fund and investment management services sectors are also doing quite
well.

   One uncertainty for the future is health care, which has been the leading 
source of job growth over the last five years.  This growth will be quite 
difficult to sustain given the present climate for health care reform, which 
has increased pressure for a more efficient health care delivery system.  Since
hospitals now have excess capacity, they are consolidating, which will lead to 
layoffs.  In addition, federal health care reform may also result in reduced 
funding for medical education at Boston's teaching hospitals.  At the same 
time, manufacturing employment is expected to continue to decline, as Digital 
Equipment and Raytheon, the state's largest private employers, proceed with 
downsizing.

   Fiscally, the state's condition has improved with a balanced budget and 
tighter financial controls.  Governor Weld and the Legislature have been 
working to keep expenses in check.

                               -2-

<PAGE>

The Outlook:  Rates May Rise Again

   After its August rate increase, the Fed paused to assess its actions.  With 
the Fed ready to move swiftly should price growth inch up above 3%, we believe 
inflation will remain under control.  In this environment, we expect short-term
rates to climb moderately higher, which should have a corresponding effect on 
your Series' yield.

   Once again, it is a pleasure to have you as a shareholder and to report our
activities to you.

Sincerely,

Lawrence C. McQuade
President


Kenneth Potts
Portfolio Manager

                               -3-


<PAGE>

PRUDENTIAL MUNICIPAL SERIES FUND       Portfolio of Investments
MASSACHUSETTS MONEY MARKET SERIES               August 31, 1994

<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                    Value
(Unaudited)     (000)             Description          (Note 1)
<C>           <C>          <S>                        <C>
                           SHORT-TERM INVESTMENTS--101.9%
                           Boston Wtr. & Swr. Comn.,
                           F.R.W.D.,
VMIG1          $   300     2.95%, 9/7/94, Ser.
                             85A....................  $   300,000
                           Chicopee Mass., B.A.N.,
NR               1,200     4.25%, 8/1/95............    1,203,690
                           Mass. Bay Trans. Auth.,
                             S.E.M.O.T.,
VMIG1            2,000     3.75%, 3/1/95, Ser.
                             84A....................    2,000,000
                           T.E.C.P.,
P-1              1,000     3.10%, 10/20/94, Ser.
                             A......................    1,000,000
                           Mass. Comnwlth., Gen.
                             Oblig., F.R.W.D.,
VMIG1            1,000     3.15%, 9/7/94, Ser.
                             92A....................    1,000,000
                           Mass. Hlth. & Edl. Facs.
                             Auth. Rev.,
                             Cap. Asset Prog.,
                           3.05%, 9/1/94, F.R.D.D.,
VMIG1              100     Ser. 85C.................      100,000
VMIG1            2,000     3.05%, 9/7/94, F.R.W.D.,
                             Ser. D.................    2,000,000
                           Childrens Hosp. Proj.,
                             F.R.W.D.,
NR               1,300     2.75%, 9/7/94, Ser.
                             94F....................    1,300,000
                           Harvard Univ., F.R.W.D.,
VMIG1            2,850     3.00%, 9/1/94, Ser.
                             85I....................    2,850,000
                           Mass. Gen. Hosp.,
Aaa              1,650(D)  7.75%, 1/1/95, Ser. D....    1,710,061
                           Tufts Univ., T.E.C.P.,
VMIG1            1,600     3.10%, 9/15/94, Ser.
                             89E....................    1,600,000
                           Wellesley Coll.,
                             F.R.W.D.,
VMIG1            1,300     2.70%, 9/7/94, Ser. E....    1,300,000
                           Mass. Hsg. Fin. Agcy.,
                             Sngl. Fam. Hsg. Rev.,
                             Q.T.R.O.T.,
Aaa              2,050     3.60%, 12/1/94, Ser. 5...    2,050,000
                           Mass. Ind. Fin. Agcy.
                             Ind. Rev.,
                             Cabot Newburyport Ltd.,
                             F.R.W.D.,
P1                 995     3.10%, 9/1/94, Ser. 94...      995,000
                           Holyoke Wtr. Pwr. Co.,
                             F.R.W.D.,
VMIG1            1,700     2.75%, 9/7/94, Ser.
                             92A....................    1,700,000
                           New England Deaconess,
                             F.R.W.D.,
VMIG1          $ 1,500     2.95%, 9/7/94, Ser.
                             93B....................  $ 1,500,000
                           Ocean Spray Cranberry,
                             A.N.N.O.T.,
NR               1,180     3.00%, 10/15/94..........    1,180,000
                           Residential Dev. Bds.,
                             F.N.M.A.,
Aaa              1,495     3.70%, 11/15/94, Ser.
                             E......................    1,497,858
                           Showa Womens Inst. Inc.,
                             F.R.D.D.,
VMIG1            1,000     3.20%, 9/1/94, Ser. 94...    1,000,000
                           United Med. Corp.,
                             F.R.W.D.,
P1                 900     3.10%, 9/7/94, Ser. 92...      900,000
                           Mass. Ind. Fin. Agcy.
                             Poll. Ctrl. Rev.,
                             New England Pwr. Co.,
                             T.E.C.P.,
VMIG1            2,000     3.15%, 10/27/94, Ser.
                             92B....................    2,000,000
                           Mass. Ind. Fin. Agcy.
                             Res. Rec. Rev.,
                             Ogden Haverhill Proj.,
                             F.R.W.D.,
VMIG1            1,800     2.90%, 9/7/94, Ser.
                             92A....................    1,800,000
                           Middleborough Mass., Gen.
                             Oblig.,
Aaa                415     5.00%, 4/15/95, Ser.
                             94.....................      418,754
                           Puerto Rico Comnwlth.,
                           Gov't. Dev. Bank.,
                           2.90%, 9/7/94, Ser. 85,
VMIG1              100     F.R.W.D.,................      100,000
                           Puerto Rico Hwy. & Trans.
                             Auth Rev., F.R.W.D.,
VMIG1            1,500     2.65%, 9/7/94............    1,500,000
                           Puerto Rico Ind.
                             Med. & Environ. Facs.,
                           Ana G. Mendez Ed. Fndtn.,
                             F.R.W.D.,
A-1*             1,500     2.90%, 9/7/94, Ser. 85...    1,500,000
                           Reynolds Metal Co. Proj.,
                             A.N.N.O.T.,
P1               1,000     4.00%, 9/1/95, Ser. 83
                             A......................    1,000,000
</TABLE>
 
                                      -4-     See Notes to Financial Statements.
 <PAGE>
<PAGE>

PRUDENTIAL MUNICIPAL SERIES FUND
MASSACHUSETTS MONEY MARKET SERIES

<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                  Value
(Unaudited)    (000)             Description          (Note 1)
<C>           <C>          <S>                        <C>
                           Puerto Rico Ind. Med. &
                             Environ. Facs.,
                           Schering-Plough Corp.,
                             A.N.N.O.T.,
AAA*           $   500     2.80%, 12/1/94, Ser.
                             83A....................  $   500,000
                           Revere Hsg. Auth.,
                           Multifamily Mtge. Rev.,
                             Waters Edge Prog.,
                             F.R.W.D.,
A-1*             1,990     3.25%, 9/2/94, Ser.
                             91C....................    1,990,000
                                                      -----------
                           Total Investments--101.9%
                           (amortized
                             cost--$37,995,363**)...   37,995,363
                           Liabilities in excess of
                             other assets--(1.9%)...     (717,259)
                                                      -----------
                           Net Assets--100%.........  $37,278,104
                                                      -----------
                                                      -----------
</TABLE>
 
- ------------------
(a) The following abbreviations are used in portfolio descriptions:
    A.N.N.O.T.--Annual Optional Tender
    B.A.N.--Bond Anticipation Note #.
    F.N.M.A.--Federal National Mortgage Association
    F.R.D.D.--Floating Rate (Daily) Demand Note #
    F.R.W.D.--Floating Rate (Weekly) Demand Note #
    Q.T.R.O.T.--Quarterly Tax & Revenue Optional Tender
    S.E.M.O.T.--Semi-Monthly Tender
    T.E.C.P.--Tax-Exempt Commercial Paper
   # For purposes of amortized cost valuation, the
     maturity date of Floating Rate Demand Notes is
     considered to be the later of the next date on
     which the security can be redeemed at par or the
     next date on which the rate of interest is
     adjusted.
   * Standard & Poor's rating.
  ** The cost of securities for federal income tax
     purposes is substantially the same as for financial
     reporting purposes.
 (D) Prerefunded issues are secured by escrowed cash
     and/or direct U.S. guaranteed obligations.
The Fund's current Statement of Additional Information
contains a description of Moody's and Standard & Poor's
ratings.
                                      -5-     See Notes to Financial Statements.

<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 MASSACHUSETTS MONEY MARKET SERIES
 Statement of Assets and Liabilities
<TABLE>
<CAPTION>
                                                                                               August 31,
Assets                                                                                           1994
                                                                                              -----------
<S>                                                                                           <C>
Investments, at amortized cost which approximates market value.............................   $37,995,363
Cash.......................................................................................       180,083
Receivable for investments sold............................................................     3,314,237
Receivable for Fund shares sold............................................................       331,090
Interest receivable........................................................................       188,432
Deferred expenses and other assets.........................................................        23,956
                                                                                              -----------
    Total assets...........................................................................    42,033,161
                                                                                              -----------
Liabilities
Payable for investments purchased..........................................................     4,067,681
Payable for Fund shares reacquired.........................................................       620,771
Accrued expenses and other liabilities.....................................................        40,459
Dividends payable..........................................................................        14,263
Distribution fee payable...................................................................         6,637
Due to Manager.............................................................................         4,236
Deferred Trustees' fees....................................................................         1,010
                                                                                              -----------
    Total liabilities......................................................................     4,755,057
                                                                                              -----------
Net Assets.................................................................................   $37,278,104
                                                                                              -----------
                                                                                              -----------
Net assets were comprised of:
  Shares of beneficial interest, at $.01 par value.........................................   $   372,781
  Paid-in capital in excess of par.........................................................    36,905,323
                                                                                              -----------
  Net assets, August 31, 1994..............................................................   $37,278,104
                                                                                              -----------
                                                                                              -----------
  Net asset value, offering price and redemption price per share ($37,278,104 / 37,278,104
    shares of
    beneficial interest issued and outstanding; unlimited number of shares authorized).....         $1.00
</TABLE>
 
See Notes to Financial Statements.
                                      -6-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 MASSACHUSETTS MONEY MARKET SERIES
 Statement of Operations
<TABLE>
<CAPTION>
                                          Year Ended
                                          August 31,
Net Investment Income                        1994
                                          ----------
<S>                                       <C>
Income
  Interest.............................   $1,052,125
                                          ----------
Expenses
  Management fee, net of waiver of
  $167,335.............................       44,800
  Distribution fee.....................       53,034
  Custodian's fees and expenses........       58,000
  Transfer agent's fees and expenses...       27,000
  Reports to shareholders..............       24,000
  Registration fees....................       20,000
  Legal fees...........................       15,000
  Amortization of organization
  expenses.............................       12,151
  Audit fee............................       10,000
  Trustees' fees.......................        3,375
  Miscellaneous........................        2,825
                                          ----------
    Total expenses.....................      270,185
    Less: expense subsidy (Note 4).....       (7,121)
                                          ----------
    Net expenses.......................      263,064
                                          ----------
Net investment income..................      789,061
                                          ----------
Net Increase in Net Assets
Resulting from Operations..............   $  789,061
                                          ----------
                                          ----------
</TABLE>

 PRUDENTIAL MUNICIPAL SERIES FUND
 MASSACHUSETTS MONEY MARKET SERIES
 Statement of Changes in Net Assets
<TABLE>
<CAPTION>
                               Year Ended August 31,
Increase (Decrease)        -----------------------------
in Net Assets                 1994             1993
                           -------------    ------------
<S>                        <C>              <C>
Operations
  Net investment
  income.................  $     789,061    $    679,277
  Net realized gain on
    investment
    transactions.........             --             369
                           -------------    ------------
  Net increase in net
    assets
    resulting from
    operations...........        789,061         679,646
                           -------------    ------------
Dividends and
  distributions to
  shareholders (Note
  1).....................       (789,061)       (679,646)
                           -------------    ------------
Series share transactions
  (at $1 per share)
  Net proceeds from
    shares
    subscribed...........    147,907,523     139,607,603
  Net asset value of
    shares
    issued to
    shareholders in
    reinvestment of
    dividends and
    distributions........        757,067         638,146
  Cost of shares
  reacquired.............   (147,994,192)   (121,656,791)
                           -------------    ------------
  Net increase in net
    assets
    from Series share
    transactions.........        670,398      18,588,958
                           -------------    ------------
Total increase...........        670,398      18,588,958
Net Assets
Beginning of year........     36,607,706      18,018,748
                           -------------    ------------
End of year..............  $  37,278,104    $ 36,607,706
                           -------------    ------------
                           -------------    ------------
</TABLE>
 
See Notes to Financial Statements.
                                      -7-
<PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 MASSACHUSETTS MONEY MARKET SERIES
 Notes to Financial Statements
   Prudential Municipal Series Fund (the ``Fund'') is registered under the
Investment Company Act of 1940, as an open-end investment company. The Fund was
organized as a Massachusetts business trust on May 18, 1984 and consists of
seventeen series. The monies of each series are invested in separate,
independently managed portfolios. The Massachusetts Money Market Series (the
``Series'') commenced investment operations on August 5, 1991. The Series is
non-diversified and seeks to provide the highest level of income that is exempt
from Massachusetts State, local and federal income taxes with the minimum of
risk by investing in ``investment grade'' tax-exempt securities having a
maturity of thirteen months or less and whose ratings are within the two highest
ratings categories by a nationally recognized statistical rating organization,
or if not rated, are of comparable quality. The ability of the issuers of the
securities held by the Series to meet their obligations may be affected by
economic developments in a specific state, industry or region.

Note 1. Accounting            The following is a summary
Policies                      of significant accounting 
                              policies followed by the Fund, and the Series, in
the preparation of its financial statements.

Securities Valuations: Portfolio securities of the Series are valued at
amortized cost, which approximates market value. The amortized cost method of
valuation involves valuing a security at its cost on the date of purchase and
thereafter assuming a constant amortization to maturity of any discount or
premium.
   All securities are valued as of 4:30 P.M., New York time.
Securities Transactions and Investment Income: Securities transactions are
recorded on the trade date. Realized gains and losses on sales of investments
are calculated on the identified cost basis. Interest income is recorded on the
accrual basis.

Federal Income Taxes: For federal income tax purposes, each series in the Fund
is treated as a separate taxpaying entity. It is the intent of the Series to
continue to meet the requirements of the Internal Revenue Code applicable to
regulated investment companies and to distribute all of its net income to
shareholders. For this reason and because substantially all of the Series' gross
income consists of tax-exempt interest, no federal income tax provision is
required.

Dividends: The Series declares daily dividends from net investment income.
Payment of dividends is made monthly. Income distributions and capital gain
distributions are determined in accordance with income tax regulations which may
differ from generally accepted accounting principles.
Deferred Organization Expenses: The Series incurred approximately $51,000 in
organization and initial registration expenses. Such amount has been deferred
and is being amortized over a period of 60 months ending July 1996.

Note 2. Agreements            The Fund has a management
                              agreement with Prudential Mutual Fund Management,
Inc. (``PMF''). Pursuant to this agreement, PMF has responsibility for all
investment advisory services and supervises the subadviser's performance of such
services. PMF has entered into a subadvisory agreement with The Prudential
Investment Corporation (``PIC''); PIC furnishes investment advisory services in
connection with the management of the Fund. PMF pays for the cost of the
subadviser's services, the compensation of officers of the Fund, occupancy and
certain clerical and bookkeeping costs of the Fund. The Fund bears all other
costs and expenses except as set forth in Note 4.
   The management fee paid PMF is computed daily and payable monthly, at an
annual rate of .50 of 1% of the average daily net assets of the Series. PMF
voluntarily waived its entire management fee until October 31, 1993. Effective
November 1, 1993, PMF reduced the management fee waiver to 75%. The amount of
fees waived for the fiscal year ended August 31, 1994 amounted to $167,335
($.004 per share; .39% of average net assets).
   The Fund has a distribution agreement with Prudential Mutual Fund
Distributors, Inc. (``PMFD''). To reimburse PMFD for its expenses incurred
pursuant to a plan of distribution, the Fund pays PMFD a reimbursement, accrued
daily and payable monthly, at an annual rate of .125 of 1% of the Series'
average daily net assets. PMFD pays various broker-dealers, including Prudential
Securities Incorporated (``PSI'') and Pruco Securities Corporation, affiliated
broker-dealers, for account servicing fees and other expenses incurred by such
broker-dealers.
   PMFD is a wholly-owned subsidiary of PMF; PSI, PMF and PIC are (indirect)
wholly-owned subsidiaries of The Prudential Insurance Company of America.
                                      -8-
<PAGE>
<PAGE>

Note 3. Other                 Prudential Mutual Fund
Transactions                  Services, Inc. (``PMFS''), a 
with Affiliates               wholly-owned subsidary of 
                              PMF, serves as the Fund's transfer agent. During
the year ended August 31, 1994, the Series incurred fees of approximately
$23,200 for the services of PMFS. As of August 31, 1994, approximately $2,000 of
such fees were due to PMFS.

Note 4. Expense               PMF voluntarily subsidized
Subsidy                       25% of the operating 
                              expenses of the Series (other than management and
distribution fees) through October 31, 1993. Effective November 1, 1993, PMF
eliminated the expense subsidy. For the fiscal year ended August 31, 1994, PMF
subsidized $7,121 ($.0002 per share; .02% of average net assets) of the Series'
expenses. The Series is not required to reimburse PMF for such expense subsidy.
                                      -9-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 MASSACHUSETTS MONEY MARKET SERIES
 Financial Highlights
<TABLE>
<CAPTION>
                                                                                                                August 5, 1991*
                                                                               Year Ended August 31,                through
                                                                        ------------------------------------      August 31,
                                                                            1994          1993        1992           1991
                                                                        ------------     -------     -------    ---------------
<S>                                                                     <C>              <C>         <C>        <C>
PER SHARE OPERATING PERFORMANCE:
Net asset value, beginning of period.................................     $   1.00       $  1.00     $  1.00        $  1.00
Net investment income and realized gains(D)..........................         .019          .021        .034           .003
Dividends and distributions to shareholders..........................        (.019)        (.021)      (.034)         (.003)
                                                                        ------------     -------     -------         ------

Net asset value, end of period.......................................     $   1.00       $  1.00     $  1.00        $  1.00
                                                                        ------------     -------     -------         ------
                                                                        ------------     -------     -------         ------

TOTAL RETURN#:.......................................................         1.89%         2.17%       3.44%          0.29%
RATIOS/SUPPLEMENTAL DATA:
Net assets, end of period (000)......................................     $ 37,278       $36,608     $18,019        $ 6,365
Average net assets (000).............................................     $ 42,427       $32,246     $15,477        $ 3,200
Ratio to average net assets:(D)
  Expenses, including distribution fee...............................         .620%         .365%       .125%          .125%**
  Expenses, excluding distribution fee...............................         .495%         .240%        .00%           .00%**
  Net investment income..............................................         1.86%         2.11%       3.20%          4.46%**
</TABLE>
 
- ---------------
   * Commencement of investment operations.
  ** Annualized.
 (D) Net of management fee waiver and expense subsidy.
   # Total returns for periods of less than a full year are not annualized.

See Notes to Financial Statements.
                                      -10-
 <PAGE>
<PAGE>
                          INDEPENDENT AUDITORS' REPORT
The Shareholders and Board of Trustees
Prudential Municipal Series Fund, Massachusetts Money Market Series
   We have audited the accompanying statement of assets and liabilities of
Prudential Municipal Series Fund, Massachusetts Money Market Series, including
the portfolio of investments, as of August 31, 1994, the related statements of
operations for the year then ended and of changes in net assets for each of the
two years in the period then ended, and the financial highlights for each of the
three years in the period then ended and for the period August 5, 1991
(commencement of investment operations) through August 31, 1991. These financial
statements and financial highlights are the responsibility of the Fund's
management. Our responsibility is to express an opinion on these financial
statements and financial highlights based on our audits.
   We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements and financial
highlights are free of material misstatement. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements. Our procedures included confirmation of the securities owned as of
August 31, 1994 by correspondence with the custodian and brokers; where replies
were not received from brokers, we performed other auditing procedures. An audit
also includes assessing the accounting principles used and significant estimates
made by management, as well as evaluating the overall financial statement
presentation. We believe that our audits provide a reasonable basis for our
opinion.
   In our opinion, such financial statements and financial highlights present
fairly, in all material respects, the financial position of Prudential Municipal
Series Fund, Massachusetts Money Market Series, as of August 31, 1994, the
results of its operations, the changes in its net assets, and its financial
highlights for the respective stated periods in conformity with generally
accepted accounting principles.
Deloitte & Touche LLP
New York, New York
October 17, 1994
                         FEDERAL INCOME TAX INFORMATION
   We are required by the Internal Revenue Code to advise you within 60 days of
the Series' fiscal year end (August 31, 1994) as to the federal tax status of
dividends paid by the Series during such fiscal year. Accordingly, we are
advising you that in the fiscal year ended August 31, 1994, dividends paid from
net investment income of $.019 per share were all federally tax-exempt interest
dividends.
                                      -11-

<PAGE>

Trustees
Edward D. Beach
Eugene C. Dorsey
Delayne Dedrick Gold
Harry A. Jacobs, Jr.
Lawrence C. McQuade
Thomas T. Mooney
Thomas H. O'Brien
Richard A. Redeker
Nancy Hays Teeters

Officers
Lawrence C. McQuade, President
Robert F. Gunia, Vice President
Susan C. Cote, Treasurer
S. Jane Rose, Secretary
Ronald Amblard, Assistant Secretary
Deborah A. Docs, Assistant Secretary

Manager
Prudential Mutual Fund Management, Inc.
One Seaport Plaza
New York, NY 10292

Investment Adviser
The Prudential Investment Corporation
Prudential Plaza
Newark, NJ 07101

Distributor
Prudential Mutual Fund Distributors, Inc.
One Seaport Plaza
New York, NY 10292

Custodian
State Street Bank and Trust Company
One Heritage Drive
North Quincy, MA 02171

Transfer Agent
Prudential Mutual Fund Services, Inc.
P.O. Box 15005
New Brunswick, NJ 08906

Independent Accountants
Deloitte & Touche LLP
1633 Broadway
New York, NY 10019

Legal Counsel
Gardner, Carton & Douglas
Quaker Tower
321 North Clark Street
Chicago, IL 60610-4795

Prudential Mutual Funds
One Seaport Plaza
New York, NY 10292
Toll free (800) 225-1852, Collect (908) 417-7555

This report is not authorized for distribution to prospective investors unless
preceded or accompanied by a current prospectus.

                                                                       MF 153E
74435M630        Prudential Mutual Fund Management (LOGO)         Cat.#444595R















ANNUAL REPORT                             August 31, 1994

Prudential
Municipal
Series Fund

(ICON)

Maryland Series

(LOGO)

<PAGE>

Letter to Shareholders

October 18, 1994 

Dear Shareholder:

It has been a most difficult year in the U.S. financial markets.  When we 
last wrote in February  interest rates were starting to rise, ending a 
three-year long bull market in bonds. What started as a trickle has 
become a torrent.  Interest rates have continued to increase this year, 
sending bond prices down sharply.  Of course, as interest rates rise, 
bond prices decline.  In this environment of falling prices and unusual 
volatility, your Prudential Municipal Series Fund -- Maryland Series 
sought to minimize risk while maximizing your tax-free income.

The Series seeks maximum income exempt from Maryland state and 
federal income taxes* consistent with preservation of capital.  
The portfolio is comprised of investment grade municipal obligations 
with an average credit quality of Aa/AA, as determined by Moody's 
Investors Service or Standard & Poor's Ratings Group.  The Series 
under performed the Lipper Maryland Municipal Debt Average over the 
last year, because as long-term interest rates rose, the Series' 
average maturity was slightly longer than the average Lipper fund.  
Expecting long-term rates to continue to rise, the adviser has 
shortened maturities.

<TABLE>
                         SERIES PERFORMANCE 
                        As of August 31, 1994
<CAPTION>
                         30-day                      Taxable Equivalent Yields
              NAV       SEC Yield                    @28%      @31%     @39.6%
<S>          <C>         <C>                         <C>       <C>      <C>
Class A      $10.66        4.8%                      7.0%      7.3%      8.4%
Class B      $10.67        4.5%                      6.7%      6.9%      7.9% 
Class C      $10.67        N/A                       N/A       N/A       N/A
</TABLE>

Investment return and principal value will fluctuate so that an 
investor's shares, when redeemed, may be worth more or less than 
their original cost.  Past performance is no guarantee of future 
results.

*Interest on municipal obligations may be subject to the federal 
alternative minimum tax. See your Series' prospectus for more details.

                               -1-

<PAGE>

<TABLE>
                          TOTAL RETURNS
<CAPTION>
              Historical (As of 8/31/94)1      Average Annual (As of 9/30/94)2
            1-Yr.       5-Yr.  Since Incep.**    1-Yr.   5-Yr. Since Incep.**
<S>         <C>         <C>       <C>            <C>     <C>      <C>
Class A     -1.8%       N/A       +36.9%         -7.8%    N/A     +5.8%
Class B     -2.1%      +37.3%     +96.7%         -10.3%  +6.0%    +7.0%
Class C      N/A        N/A       +0.1%           N/A     N/A     -3.0%
Lipper MD
Muni Debt 
Avg.***    -1.2%      +42.0%    103.4%           N/A     N/A      N/A
</TABLE>

 Source: Lipper Analytical Services, Inc. These figures do not take 
into account sales charges.

2 Source: Prudential Mutual Fund Management, Inc.  These averages take 
into account applicable sales charges.  The Series charges a maximum 
initial sales charge of 3% for Class A shares.  Class B shares are subject 
to a declining contingent deferred sales charge of 5%, 4%, 3%, 2%, 1% and 
1%, respectively, for the first six years.  Class B shares will 
automatically convert to Class A shares approximately seven years 
after purchase.  This conversion feature is expected to be implemented 
in February 1995. Class C shares are sold subject to a contingent 
deferred sales charge of 1% during the first year. 

**Inception on January 22, 1990 for Class A, and January 22, 1985 
for Class B and August 1, 1994 for Class C.

***These are the average returns of 23 Maryland municipal debt funds 
for one-year, five-year, and since inception of Class B shares, as 
determined by Lipper Analytical Services, Inc.

Once Was Not Enough

When we wrote to you in February, the Federal Reserve raised short-term 
interest rates for the first time in years, hoping to control inflation.  
Since then, the Fed has moved four more times, until the federal funds 
rate (the overnight interbank lending rate) now stands at 4.75%, up from 
3% at the start of the year.  The Fed also increased the discount rate 
(at which it lends banks money) to 4% from 3% over the same period.

Interest rates rise when the financial markets fear inflation, the bond 
holder's enemy. Inflation is feared because it robs purchasing power 
from a bond's fixed-interest rate.

Municipal bond interest rates increased by more than a 
percentage point, to 6.46% on August 25 from 5.52% on December 29, 
1993, as measured by the Bond Buyer's Revenue Bond Index, a widely 
used yardstick of interest rates in the tax-free market.

Maryland: Slow, Stable Growth

Maryland's economy is primarily comprised of trade, government and 
services; it ranks eighth in the nation in federal procurement dollars 
per capita.  Since the state is more dependent on government employment 
than on manufacturing, its escaped the worst of the recession.  However, 
this economic structure also means that economic growth in the recovery 
is slow.

The state's finances are different from others in several respects.  
It is among the most heavily indebted of states, but largely because 
it has assumed local school construction costs.  In recent years, 
Maryland has limited its borrowing; in fiscal 1995, it will issue 
no more than $380 million in general obligation bonds.

                                 -2-

<PAGE>

In general, the state has consistently demonstrated strong 
financial controls, making either deep cuts or raising taxes 
when necessary.  Its bonds are rated AAA/Aaa, the highest available, 
by both major rating services.

The Maryland market offers opportunities to buy bonds for multi-family 
housing which traditionally offers higher yields.

A Tax Reminder

As a result of the federal Revenue Reconciliation Act of 1993, which 
affects bonds purchased after April 30, 1993,  it is possible that this 
year you may have some taxable income from your tax-free municipal 
bond fund.  The law stipulates that the portion of any gain realized 
on the sale or retirement of a tax-free bond purchased at a market 
discount to its face value must be taxed as ordinary income.

As a result of this change in federal tax law, some discount bonds 
have been selling at levels so cheap they will produce a higher after-tax 
return than other bonds not subject to the provisions of the new law.  
We have occasionally taken advantage of this market imbalance 
because we have determined that at very low prices these bonds can still 
provide you with a higher after-tax return on your investment.

The Outlook

We expect continued volatility in the municipal bond market until the 
economy reaches a level of growth that is sustainable without 
causing inflation.  If the economy continues to surge, the ever 
vigilant Fed will move again, lifting short-term rates.  If the 
economy slows substantially, long term rates should stabilize.  
Although rates may keep rising, we believe that most of the increase 
is now behind us.

In the months ahead, we expect supply -- or the lack of it -- to 
become more important in the tax-free municipal bond market.  Through 
the first eight months of the year, new issue volume is off 42%,  
according to Securities Data Co., which tracks this statistic.  The 
pace is accelerating.  In August, new issue volume fell 56%.  

                                 -3-

<PAGE>

As always, it is a pleasure to have you as a shareholder in the 
Prudential Municipal Series Fund -- Maryland Series, and to take 
this opportunity to report our activities to you.


Sincerely,


Lawrence C. McQuade
President


Marie Conti
Portfolio Manager

                                  -4-

<PAGE>

PRUDENTIAL MUNICIPAL SERIES FUND              Portfolio of Investments
MARYLAND SERIES                                       August 31, 1994

<TABLE>
<CAPTION>
  Moody's     Principal                                         
   Rating      Amount                                    Value  
(Unaudited)     (000)           Description (a)        (Note 1) 

<C>           <C>          <S>                       <C>
                           LONG-TERM INVESTMENTS--94.0%
                           Anne Arundel Cnty.,
                           Cons. Gen. Impvt.,
Aa1            $  1,000    6.00%, 7/15/11..........  $ 1,015,540
                           Baltimore Cert. of
                             Part.,
Aaa               1,000    5.25%, 4/1/16,
                             M.B.I.A...............      885,570
                           Pension Funding,
                             M.B.I.A.,
Aaa               1,000(D) 7.25%, 4/1/16, Ser. A...    1,124,080
                           Baltimore Econ. Dev.
                             Lease
                           Rev., Armistead
                             Partnership,
BBB+*             1,000    7.00%, 8/1/11...........    1,024,440
                           Baltimore Maryland Conv.
                             Ctr. Rev.,
Aaa               1,075    5.75%, 9/1/08,
                             F.G.I.C...............    1,076,602
Aaa               1,250    6.15%, 9/1/19,
                             F.G.I.C...............    1,243,675
                           Baltimore Util. Pub.
                             Impvt.,
                           7.00%, 10/15/09,
                             Ser. A, M.B.I.A.......      557,675
Aaa                 500
                           Charles Cnty., Gen.
                             Oblig.,
A1                1,580(D) 6.375%, 12/1/03.........    1,713,384
                           Dist. of Columbia Met.
                             Area
                             Transit Auth. Gross
                             Rev.,
Aaa                 600    6.00%, 7/1/09,
                             F.G.I.C...............      611,166
Aaa               1,500    5.25%, 7/1/14,
                             F.G.I.C...............    1,330,650
                           Gaithersburg Econ. Dev.
                             Rev.,
                             Asbury Methodist,
NR                1,000    5.50%, 1/1/20...........      874,250
                           Harford Cnty.,
                             Cons. Pub. Impvt.,
Aa                1,500    4.90%, 12/1/10..........    1,335,810
                           Howard Cnty., Met.
                             Dist.,
Aa1               2,115    Zero Coupon, 8/15/09,
                             Ser. B................      896,781
                           Kent Cnty., Coll. Rev.
                             Proj. & Ref.,
                             Washington Coll.
                             Proj.,
Baa1              1,500    7.70%, 7/1/18...........    1,631,910
                           Maryland St. Hlth. &
                             Higher Edl. Facs.
                             Auth. Rev.,
                           Baltimore Cnty., Gen.
                             Hosp.,
Aaa                 750(D) 7.75%, 7/1/13,
                             A.M.B.A.C.............      839,895
                           Broadmead Proj.,
NR                  500    7.625%, 7/1/10..........      530,070
                           Maryland St. Hlth. &
                             Higher Edl. Facs.
                             Auth. Rev.,
                           Church Hosp.,
A              $    500    8.00%, 7/1/13...........  $   548,000
                           Franklin Square Hosp.,
Aaa               1,000    7.50%, 7/1/19,
                             M.B.I.A...............    1,115,870
                           Good Samaritan Hosp.,
A                 1,100    5.75%, 7/1/19...........    1,011,527
                           Hartford Mem. Hosp.
                             & Fallston,
Baa1                750    8.50%, 7/1/14...........      820,013
                           Howard Cnty. Gen. Hosp.,
Baa1              1,000(D) 7.00%, 7/1/17...........    1,080,850
                           John Hopkins Med. Ctr.,
Aa                2,000    5.00%, 7/1/23...........    1,651,560
                           Montgomery Gen. Hosp.,
Baa1              1,500    5.00%, 7/1/23...........    1,221,735
                           No. Arundel Hosp.,
Aaa               1,250(D) 7.875%, 7/1/21,
                             B.I.G.................    1,405,712
                           Peninsula Reg. Med.,
A                 1,200    5.00%, 7/1/23...........      966,756
                           Roland Park Proj.,
NR                1,000    7.75%, 7/1/12...........    1,076,020
                           Sinai Hosp. of
                             Baltimore,
Aaa                 500    5.25%, 7/1/19,
                             A.M.B.A.C.............      433,915
Aaa                 600    5.25%, 7/1/23,
                             A.M.B.A.C.............      515,952
                           Maryland St. Hsg. &
                             Cmnty. Dev. Admin.,
                             Sngl. Fam. Mtge. Rev.
                             Proj.,
Aa                  850    7.125%, 4/1/14, Sixth
                             Ser...................      880,507
Aa                  925@   7.70%, 4/1/15, Fourth
                             Ser...................      965,274
Aa                  750    8.00%, 4/1/18, Third
                             Ser...................      808,035
                           Maryland St. Ind. Auth.
                             Econ. Dev.,
                             Holy Cross Hlth. Sys.
                             Corp.,
A1                1,500    5.50%, 12/1/15..........    1,358,700
                           Maryland St. Ind. Dev.
                             Fin. Auth. Rev.,
                             Amer. Ctr. For
                             Physics,
BBB*              1,000    6.625%, 1/1/17..........      994,680
</TABLE>
 
                                    -5-     See Notes to Financial Statements.

<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND              
MARYLAND SERIES                              
<TABLE>
<CAPTION>
  Moody's     Principal                                         
   Rating      Amount                                    Value  
(Unaudited)     (000)           Description (a)        (Note 1) 

<C>           <C>          <S>                       <C>
                           Maryland Wtr. Quality
                             Fin. Admin.,
                             Revolving Loan Fund
                             Rev.,
A1             $  1,000    7.25%, 9/1/12, Ser. B...  $ 1,100,690
Aa                  500    5.40%, 9/1/13...........      461,470
                           Montgomery Cnty. Hsg.
                             Opportunities Comn.,
                             Multifamily Mtge.
                             Rev.,
A                 1,000    7.00%, 7/1/23...........    1,024,100
                           Sngl. Fam. Mtge. Rev.,
Aa                1,440    7.625%, 7/1/17, Ser.
                             A.....................    1,487,146
                           Montgomery Cnty., Cons.
                             Pub. Impvt.,
Aaa                 450    9.75%, 6/1/01...........      569,344
                           Northeast Waste Disp.
                             Auth.,
                             Baltimore City Sludge
                             Proj.,
NR                  957    7.25%, 7/1/07...........      959,230
                           Montgomery Cnty. Proj.,
A                 2,200    6.30%, 7/1/16...........    2,141,304
                           Prince Georges Cnty.
                             Hsg. Auth. Mtge. Rev.,
                             Laurel Apts.,
AAA*                750    6.25%, 4/20/20,
                             F.N.M.A...............      747,075
                           Prince Georges Cnty.,
                             Cons. Pub. Impvt.,
A1                  750    5.00%, 1/15/09..........      675,037
                           Hosp. Rev., Dimensions
                             Hlth. Corp.,
A                 1,250    5.30%, 7/1/24...........    1,032,150
                           Stormwater Mgmt.,
Aa                1,140    6.50%, 3/15/03..........    1,231,314
                           Puerto Rico Comnwlth.
                             Aqueduct & Swr. Auth.
                             Rev.,
Aaa                 100    10.125%, 7/1/99.........      121,272
Aaa                 225    10.25%, 7/1/09..........      310,894
                           Puerto Rico Comnwlth.,
                             Gen. Oblig.,
Aaa               1,000(D)(D) 8.39%, 7/1/20, F.S.A....     937,500
                           Puerto Rico Tel. Auth.
                             Rev.,
                           M.B.I.A., Ser. I,
Aaa               1,000(D)(D) 7.38%, 1/16/15..........     868,750
                           Virgin Islands Pub. Fin.
                             Auth. Rev.,
                             Ref. Matching Loan
                             Notes,
NR                  600    7.25%, 10/1/18, Ser.
                             A.....................      618,972
                           Virgin Islands Wtr. & Pwr. Auth.,
                             Wtr. Sys. Rev.,
NR             $    600    8.50%, 1/1/10, Ser. A...  $   659,136
                           Washington Suburban San. Dist.,
                             Gen. Construction,
Aa1               1,500    5.25%, 6/1/12...........    1,370,340
Aa1               1,000    5.25%, 6/1/16, Ser. 2...      904,940
                                                     -----------
                           Total long-term
                             investments
                             (cost $50,079,943)....   50,767,268
                                                     -----------
                           SHORT-TERM INVESTMENTS--5.0%
                           Puerto Rico Comnwlth.,
                             Gov't. Dev. Bank.,
                             F.R.W.D.,
VMIG1             2,700    2.90%, 9/7/94, Ser.
                             85....................    2,700,000
                                                     -----------
                           Total Investments--99.0%
                           (cost $52,779,943; Note
                             4)....................   53,467,268
                           Other assets in excess
                             of
                             liabilities--1.0%.....      542,358
                                                     -----------
                           Net Assets--100%........  $54,009,626
                                                     -----------
                                                     -----------
</TABLE>
 
- ------------------
(a) The following abbreviations are used in portfolio descriptions:
    A.M.B.A.C.--American Municipal Bond Assurance Corporation.
    B.I.G.--Bond Investors Guaranty Insurance Company.
    F.G.I.C.--Financial Guaranty Insurance Company.
    F.N.M.A.--Federal National Mortgage Association.
    F.R.W.D.--Floating Rate (Weekly) Demand Note #.
    F.S.A.--Financial Security Assurance.
    M.B.I.A.--Municipal Bond Insurance Association.
   # For purposes of amortized cost valuation, the
     maturity date of Floating Rate Demand Notes is
     considered to be the later of the next date on
     which the security can be redeemed at par, or the
     next date on which the rate of interest is
     adjusted.
   * Standard & Poor's Rating.
   (D) Prerefunded issues are secured by escrowed cash
       and/or direct U.S. guaranteed obligations.
(D)(D) Inverse floating rate bond. The coupon is
      inversely indexed to a floating interest rate.
      The rate shown is the rate at period end.
    @ Pledged as initial margin on financial futures
      contracts.
NR--Not Rated by Moody's or Standard & Poor's.
The Fund's current Statement of Additional Information contains a description 
of Moody's and Standard & Poor's ratings.
                                    -6-     See Notes to Financial Statements.

<PAGE>

 PRUDENTIAL MUNICIPAL SERIES FUND
 MARYLAND SERIES
 Statement of Assets and Liabilities

<TABLE>
<CAPTION>
                                                                                                   August 31,
Assets                                                                                                1994
                                                                                                   -----------
<S>                                                                                                <C>
Investments, at value (cost $52,779,943)........................................................   $53,467,268
Cash............................................................................................       127,565
Interest receivable.............................................................................       715,877
Receivable for Fund shares sold.................................................................         4,241
Other assets....................................................................................         1,720
                                                                                                   -----------
  Total assets..................................................................................    54,316,671
                                                                                                   -----------
Liabilities
Payable for Fund shares reacquired..............................................................       169,424
Accrued expenses................................................................................        42,893
Dividends payable...............................................................................        40,085
Management fee payable..........................................................................        23,061
Distribution fee payable........................................................................        22,135
Due to broker - variation margin payable........................................................         8,437
Deferred trustee fees...........................................................................         1,010
                                                                                                   -----------
  Total liabilities.............................................................................       307,045
                                                                                                   -----------
Net Assets......................................................................................   $54,009,626
                                                                                                   -----------
                                                                                                   -----------
Net assets were comprised of:
  Shares of beneficial interest, at par.........................................................   $    50,616
  Paid-in capital in excess of par..............................................................    52,925,885
                                                                                                   -----------
                                                                                                    52,976,501
  Accumulated net realized gain on investments..................................................       311,487
  Net unrealized appreciation of investments....................................................       721,638
                                                                                                   -----------
  Net assets, August 31, 1994...................................................................   $54,009,626
                                                                                                   -----------
                                                                                                   -----------
Class A:
  Net asset value and redemption price per share ($2,709,407 / 254,247 shares of beneficial
    interest issued and outstanding)............................................................        $10.66
  Maximum sales charge (3.0% of offering price).................................................           .33
                                                                                                   -----------
  Maximum offering price to public..............................................................        $10.99
                                                                                                   -----------
                                                                                                   -----------
Class B:
  Net asset value, offering price and redemption price per share ($51,198,286 / 4,797,823 shares
    of beneficial interest issued and outstanding)...............................................        $10.67
                                                                                                   -----------
                                                                                                   -----------
Class C:
  Net asset value, offering price and redemption price per share ($101,933 / 9,552 shares of
    beneficial interest issued and outstanding).................................................        $10.67
                                                                                                   -----------
                                                                                                   -----------
</TABLE>
 
See Notes to Financial Statements.
                                      -7-
 <PAGE>
<PAGE>

 PRUDENTIAL MUNICIPAL SERIES FUND
 MARYLAND SERIES
 Statement of Operations
<TABLE>
<CAPTION>
                                            Year Ended
                                            August 31,
Net Investment Income                          1994
                                            -----------
<S>                                         <C>
Income
  Interest...............................   $ 3,559,061
                                            -----------
Expenses
  Management fee.........................       290,509
  Distribution fee--Class A..............         2,877
  Distribution fee--Class B..............       276,113
  Distribution fee--Class C..............            18
  Custodian's fees and expenses..........        86,000
  Transfer agent's fees and expenses.....        38,000
  Reports to shareholders................        27,000
  Registration fees......................        19,100
  Legal fees.............................        15,000
  Audit fee..............................        10,500
  Trustees' fees.........................         3,375
  Miscellaneous..........................         5,012
                                            -----------
    Total expenses.......................       773,504
                                            -----------
  Net investment income..................     2,785,557
                                            -----------
Realized and Unrealized
Gain (Loss) on Investments
Net realized gain on:
  Investment transactions................       648,535
  Financial futures contract
  transactions...........................         9,600
                                            -----------
                                                658,135
                                            -----------
Net change in unrealized
  appreciation/depreciation of:
  Investments............................    (4,779,083)
  Financial futures contracts............        63,188
                                            -----------
                                             (4,715,895)
                                            -----------
Net loss on investments..................    (4,057,760)
                                            -----------
Net Decrease in Net Assets
Resulting from Operations................   $(1,272,203)
                                            -----------
                                            -----------
</TABLE>
 
 PRUDENTIAL MUNICIPAL SERIES FUND
 MARYLAND SERIES
 Statement of Changes in Net Assets

<TABLE>
<CAPTION>
                                   Year Ended August 31,
Increase (Decrease)              --------------------------
in Net Assets                        1994          1993
                                 ------------   -----------
<S>                              <C>            <C>
Operations
  Net investment income........  $  2,785,557   $ 2,860,729
  Net realized gain on
    investment transactions....       658,135     1,079,334
  Net change in unrealized
    appreciation/depreciation
    of investments.............    (4,715,895)    2,218,425
                                 ------------   -----------
  Net increase (decrease) in
    net assets resulting from
    operations.................    (1,272,203)    6,158,488
                                 ------------   -----------
Dividends and distributions
  (Note 1):
  Dividends from net investment
    income
    Class A....................      (149,002)     (112,413)
    Class B....................    (2,636,439)   (2,748,316)
    Class C....................          (116)           --
                                 ------------   -----------
                                   (2,785,557)   (2,860,729)
                                 ------------   -----------
  Distributions from net
    realized gains
    Class A....................       (53,117)      (18,889)
    Class B....................    (1,057,112)     (562,219)
                                 ------------   -----------
                                   (1,110,229)     (581,108)
                                 ------------   -----------
Series share transactions (Note
  5)
  Net proceeds from shares
    sold.......................     5,404,805     8,738,496
  Net asset value of shares
    issued in reinvestment of
    dividends and
    distributions..............     2,685,739     2,374,657
  Cost of shares reacquired....    (9,441,263)   (5,949,464)
                                 ------------   -----------
  Net increase (decrease) in
    net assets from Series
    share transactions.........    (1,350,719)    5,163,689
                                 ------------   -----------
Total increase (decrease)......    (6,518,708)    7,880,340
Net Assets
Beginning of year..............    60,528,334    52,647,994
                                 ------------   -----------
End of year....................  $ 54,009,626   $60,528,334
                                 ------------   -----------
                                 ------------   -----------
</TABLE>
 
See Notes to Financial Statements.        See Notes to Financial Statements.
                                      -8-
 <PAGE>
<PAGE>

 PRUDENTIAL MUNICIPAL SERIES FUND
 MARYLAND SERIES

 Notes to Financial Statements
   Prudential Municipal Series Fund (the ``Fund'') is registered under the
Investment Company Act of 1940, as an open-end investment company. The Fund was
organized as a Massachusetts business trust on May 18, 1984 and consists of
seventeen series. The monies of each series are invested in separate,
independently managed portfolios. The Maryland Series (the ``Series'') commenced
investment operations in January, 1985. The Series is diversified and seeks to
achieve its investment objective of obtaining the maximum amount of income
exempt from federal and applicable state income taxes with the minimum of risk
by investing in ``investment grade'' tax-exempt securities whose ratings are
within the four highest ratings categories by a nationally recognized
statistical rating organization or, if not rated, are of comparable quality. The
ability of the issuers of the securities held by the Series to meet their
obligations may be affected by economic or political developments in a specific
state, industry or region.
                              
Note 1. Accounting            The following is a summary
Policies                      of significant accounting poli-
                              cies followed by the Fund, and the Series, in the
preparation of its financial statements.
Securities Valuations: The Fund values municipal securities (including
commitments to purchase such securities on a ``when-issued'' basis) on the basis
of prices provided by a pricing service which uses information with respect to
transactions in bonds, quotations from bond dealers, market transactions in
comparable securities and various relationships between securities in
determining values. If market quotations are not readily available from such
pricing service, a security is valued at its fair value as determined under
procedures established by the Trustees.
   Short-term securities which mature in more than 60 days are valued at current
market quotations. Short-term securities which mature in 60 days or less are
valued at amortized cost.
   All securities are valued as of 4:15 P.M., New York time.
Financial Futures Contracts: A financial futures contract is an agreement to
purchase (long) or sell (short) an agreed amount of debt securities at a set
price for delivery on a future date. Upon entering into a financial futures
contract, the Series is required to pledge to the broker an amount of cash
and/or other assets equal to a certain percentage of the contract amount. This
amount is known as the ``initial margin''. Subsequent payments, known as
``variation margin'', are made or received by the Series each day, depending on
the daily fluctuations in the value of the underlying security. Such variation
margin is recorded for financial statement purposes on a daily basis as
unrealized gain or loss. The Series invests in financial futures contracts
solely for the purpose of hedging its existing portfolio securities or
securities the Series intends to purchase against fluctuations in value caused
by changes in prevailing market conditions. Should market conditions move
unexpectedly, the Series may not achieve the anticipated benefits of the
financial futures contracts and may realize a loss. The use of futures
transactions involves the risk of imperfect correlation in movements in the
price of futures contracts, interest rates and the underlying hedged assets.
Securities Transactions and Investment Income: Securities transactions are
recorded on the trade date. Realized gains and losses on sales of securities are
calculated on the identified cost basis. Interest income is recorded on the
accrual basis. The Series amortizes premiums and original issue discount paid on
purchases of portfolio securities as adjustments to interest income.
   Net investment income (other than distribution fees) and unrealized and
realized gains or losses are allocated daily to each class of shares based upon
the relative proportion of net assets of each class at the beginning of the day.
Federal Income Taxes: For federal income tax purposes, each series in the Fund
is treated as a separate taxpaying entity. It is the intent of the Series to
continue to meet the requirements of the Internal Revenue Code applicable to
regulated investment companies and to distribute all of its net income to
shareholders. For this reason and because substantially all of the Series' gross
income consists of tax-exempt interest, no federal income tax provision is
required.
Dividends and Distributions: The Series declares daily dividends from net
investment income. Payment of dividends is made monthly. Distributions of net
capital gains, if any, are made annually.
   Income distributions and capital gain distributions are determined in
accordance with income tax regulations which may differ from generally accepted
accounting principles.
                              
Note 2. Agreements            The Fund has a management
                              agreement with Prudential Mutual Fund Management,
Inc. (``PMF''). Pursuant to this
                                      -9-
 <PAGE>
<PAGE>
agreement, PMF has responsibility for all investment advisory services and
supervises the subadviser's performance of such services. PMF has entered into a
subadvisory agreement with The Prudential Investment Corporation (``PIC''). PIC
furnishes investment advisory services in connection with the management of the
Fund. PMF pays for the services of PIC, the cost of compensation of officers of
the Fund, occupancy and certain clerical and bookkeeping costs of the Fund. The
Fund bears all other costs and expenses.
   The management fee paid PMF is computed daily and payable monthly, at an
annual rate of .50 of 1% of the average daily net assets of the Series.
   The Fund has distribution agreements with Prudential Mutual Fund
Distributors, Inc. (``PMFD''), which acts as the distributor of the Class A
shares of the Fund, and with Prudential Securities Incorporated (``PSI''), which
acts as distributor of the Class B and Class C shares of the Fund (collectively
the ``Distributors''). The Fund compensates the Distributors for distributing
and servicing the Fund's Class A, Class B and Class C shares, pursuant to plans
of distribution (the ``Class A, B and C Plans''), regardless of expenses
actually incurred by them. The distribution fees are accrued daily and payable
monthly.
   On July 19, 1994, shareholders of the Fund approved amendments to the Class A
and Class B distribution plans under which the distribution plans became
compensation plans, effective August 1, 1994. Prior thereto, the distribution
plans were reimbursement plans, under which PMFD and PSI were reimbursed for
expenses actually incurred by them up to the amount permitted under the Class A
and Class B Plans, respectively. The Fund is not obligated to pay any prior or
future excess distribution costs (costs incurred by the Distributors in excess
of distribution fees paid by the Fund or contingent deferred sales charges
received by the Distributors). The rate of the distribution fees charged to
Class A and Class B shares of the Fund did not change under the amended plans of
distribution. The Fund began offering Class C shares on August 1, 1994.
   Pursuant to the Class A, B and C Plans, the Fund compensates the Distributors
for distribution-related activities at an annual rate of up to .30 of 1%, .50 of
1% and 1%, of the average daily net assets of the Class A, B and C shares,
respectively. Such expenses under the Plans were .10 of 1%, .50 of 1% and .75 of
1% of the average daily net assets of the Class A, B and C shares, respectively,
for the fiscal year ended August 31, 1994.
   PMFD has advised the Series that it has received approximately $27,000 in
front-end sales charges resulting from sales of Class A shares during the fiscal
year ended August 31, 1994. From these fees, PMFD paid such sales charges to PSI
and Pruco Securities Corporation, affiliated broker-dealers, which in turn paid
commissions to salespersons and incurred other distribution costs.
   PSI has advised the Series that for the fiscal year ended August 31, 1994, it
received approximately $64,000 in contingent deferred sales charges imposed upon
certain redemptions by Class B shareholders.
   PMFD is a wholly-owned subsidiary of PMF; PSI, PMF and PIC are indirect,
wholly-owned subsidiaries of The Prudential Insurance Company of America.
                              
Note 3. Other                 Prudential Mutual Fund Ser-
Transactions                  vices, Inc. (``PMFS''), a 
With Affiliates               wholly-owned subsidiary of 
                              PMF, serves as the Fund's transfer agent. During
the year ended August 31, 1994, the Series incurred fees of approximately
$27,200 for the services of PMFS. As of August 31, 1994, approximately $2,200 of
such fees were due to PMFS. Transfer agent fees and expenses in the Statement of
Operations include certain out-of-pocket expenses paid to non-affiliates.
                              
Note 4. Portfolio             Purchases and sales of port-
Securities                    folio securities of the Series, 
                              excluding short-term investments, for the year
ended August 31, 1994 were $21,768,235 and $24,842,862, respectively.
   At August 31, 1994, the Fund sold 30 financial futures contracts on the
Municipal Bond Index expiring in September 1994. The value at disposition of
such contracts is $2,779,313. The value of such contracts on August 31, 1994 
was $2,745,000, thereby resulting in an unrealized gain of $34,313.
   The cost basis of investments for federal income tax purposes is
substantially the same as for financial reporting purposes and, accordingly, as
of August 31, 1994, net unrealized appreciation of investments for federal
income tax purposes is $687,325 (gross unrealized appreciation--$2,119,312;
gross unrealized depreciation $1,431,987).
                              
Note 5. Capital               The Series currently offers
                              Class A, Class B and Class C shares. Class A
shares are sold with a front-end sales charge of up to 3.0%. Class B shares are
sold with a contingent deferred sales charge which declines from 5% to zero
depending on the period of time the shares are held. Class C shares are sold
with a contingent deferred sales charge of 1% during the first year. Class B
shares will automatically convert to Class A shares on a quarterly basis
approximately seven
                                      -10-
 <PAGE>
<PAGE>
years after purchase commencing in or about February 1995.
   The Fund has authorized an unlimited number of shares of beneficial interest
of each class at $.01 par value per share. Transactions in shares of beneficial
interest for the fiscal years ended August 31, 1994 and 1993 were as follows:

<TABLE>
<CAPTION>
Class A                              Shares       Amount
<S>                                 <C>         <C>
                                    --------    -----------
Year ended August 31, 1994:
Shares sold......................     74,702    $   830,474
Shares issued in reinvestment
  of dividends and
  distributions..................     12,858        143,277
Shares reacquired................    (85,098)      (937,854)
                                    --------    -----------
Net increase in shares
  outstanding....................      2,462    $    35,897
                                    --------    -----------
                                    --------    -----------
Year ended August 31, 1993:
Shares sold......................    178,669    $ 2,012,997
Shares issued in reinvestment
  of dividends and
  distributions..................      9,349        104,954
Shares reacquired................    (56,465)      (642,673)
                                    --------    -----------
Net increase in shares
  outstanding....................    131,553    $ 1,475,278
                                    --------    -----------
                                    --------    -----------
</TABLE>
 
<TABLE>
<CAPTION>

Class B                              Shares       Amount
<S>                                 <C>         <C>
                                    --------    -----------
Year ended August 31, 1994:
Shares sold......................    399,067    $ 4,473,113
Shares issued in reinvestment
  of dividends and
  distributions..................    228,006      2,542,431
Shares reacquired................   (772,159)    (8,503,409)
                                    --------    -----------
Net decrease in shares
  outstanding....................   (145,086)   $(1,487,865)
                                    --------    -----------
                                    --------    -----------
Year ended August 31, 1993:
Shares sold......................    598,587    $ 6,725,499
Shares issued in reinvestment
  of dividends and
  distributions..................    202,460      2,269,703
Shares reacquired................   (473,226)    (5,306,791)
                                    --------    -----------
Net increase in shares
  outstanding....................    327,821    $ 3,688,411
                                    --------    -----------
                                    --------    -----------
</TABLE>
 
<TABLE>
<CAPTION>

Class C
<S>                                 <C>         <C>
August 1, 1994* through
  August 31, 1994:
Shares sold......................      9,549    $   101,218
Shares issued in reinvestment
  of dividends...................          3             31
                                    --------    -----------
Net increase in shares
  outstanding....................      9,552    $   101,249
                                    --------    -----------
                                    --------    -----------
</TABLE>
 
- ---------------
* Commencement of offering of Class C shares.
                                      -11-
 <PAGE>
<PAGE>

 PRUDENTIAL MUNICIPAL SERIES FUND
 MARYLAND SERIES
 Financial Highlights

<TABLE>
<CAPTION>
                                                          Class A                                       Class B
                                   -----------------------------------------------------   --------------------------------
                                                                             January 22, 
                                                                               1990(D)
                                            Year Ended August 31,             through          Year Ended August 31,
                                   ---------------------------------------   August 31,    --------------------------------
                                       1994        1993     1992     1991       1990           1994        1993      1992
<S>                                <C>            <C>      <C>      <C>      <C>           <C>            <C>       <C>
                                   ------------   ------   ------   ------   -----------   ------------   -------   -------
PER SHARE OPERATING PERFORMANCE:
Net asset value, beginning of
  period.........................     $11.64      $11.11   $10.67   $10.23     $ 10.44       $  11.65     $ 11.12   $ 10.68
                                      ------      ------   ------   ------   -----------   ------------   -------   -------
Income from investment operations
Net investment income............        .57         .62      .63      .67         .40            .53         .58       .59
Net realized and unrealized gain
  (loss) on investment
  transactions...................       (.77)        .65      .44      .44        (.21)          (.77)        .65       .44
                                      ------      ------   ------   ------   -----------   ------------   -------   -------
  Total from investment
    operations...................       (.20)       1.27     1.07     1.11         .19           (.24)       1.23      1.03
                                      ------      ------   ------   ------   -----------   ------------   -------   -------
Less distributions
Dividends from net investment
  income.........................       (.57)       (.62)    (.63)    (.67)       (.40)          (.53)       (.58)     (.59)
Distributions from net realized
  gains..........................       (.21)       (.12)      --       --          --           (.21)       (.12)       --
                                      ------      ------   ------   ------   -----------   ------------   -------   -------
  Total distributions............       (.78)       (.74)    (.63)    (.67)       (.40)          (.74)       (.70)     (.59)
                                      ------      ------   ------   ------   -----------   ------------   -------   -------
Net asset value, end of period...     $10.66      $11.64   $11.11   $10.67     $ 10.23       $  10.67     $ 11.65   $ 11.12
                                      ------      ------   ------   ------   -----------   ------------   -------   -------
                                      ------      ------   ------   ------   -----------   ------------   -------   -------
TOTAL RETURN#:...................      (1.75)%     11.89%   10.35%   10.84%       1.71%         (2.13)%     11.43%     9.90%
RATIOS/SUPPLEMENTAL DATA:
Net assets, end of period
  (000)..........................     $2,709      $2,930   $1,335   $  804     $   349       $ 51,198     $57,598   $51,313
Average net assets (000).........     $2,877      $2,068   $1,080   $  518     $   141       $ 55,223     $53,780   $50,970
Ratios to average net assets:##
  Expenses, including
    distribution fees............        .95%        .96%     .96%    1.10%       1.01%*         1.35%       1.36%     1.37%
  Expenses, excluding
    distribution fees............        .85%        .86%     .86%    1.00%        .91%*          .85%        .86%      .87%
  Net investment income..........       5.18%       5.51%    5.80%    6.07%       6.31%*         4.77%       5.11%     5.42%
Portfolio turnover...............         40%         41%      34%      18%         46%            40%         41%       34%

<CAPTION>
                                                        Class C
                                                       ----------
                                                       August 1,
                                                       1994(D)(D)
                                                        through
                                                       August 31,
                                    1991      1990        1994
<S>                                <C>       <C>       <C>
                                   -------   -------   ----------
PER SHARE OPERATING PERFORMANCE:
Net asset value, beginning of
  period.........................  $ 10.23   $ 10.48    $  10.70
                                   -------   -------   ----------
Income from investment operations
Net investment income............      .63       .62         .05
Net realized and unrealized gain
  (loss) on investment
  transactions...................      .45      (.25)       (.03)
                                   -------   -------   ----------
  Total from investment
    operations...................     1.08       .37         .02
                                    -------   -------   ----------
Less distributions
Dividends from net investment
  income.........................     (.63)     (.62)       (.05)
Distributions from net realized
  gains..........................       --        --          --
                                    -------   -------   ----------
  Total distributions............     (.63)     (.62)       (.05)
                                    -------   -------   ----------
Net asset value, end of period...  $ 10.68   $ 10.23    $  10.67
                                   -------   -------   ----------
                                   -------   -------   ----------
TOTAL RETURN#:...................    10.49%     3.58%        .07%
RATIOS/SUPPLEMENTAL DATA:
Net assets, end of period
  (000)..........................  $51,110   $48,226    $    102
Average net assets (000).........  $48,422   $48,573    $     31
Ratios to average net assets:##
  Expenses, including
    distribution fees............     1.49%     1.40%       2.21%*
  Expenses, excluding
    distribution fees............      .99%      .92%       1.47%*
  Net investment income..........     5.70%     5.95%       4.75%*
Portfolio turnover...............       18%       46%         40%
</TABLE>

- ---------------
     * Annualized.
   (D) Commencement of offering of Class A shares.
(D)(D) Commencement of offering of Class C shares.
     # Total return does not consider the effects of sales loads. Total return 
       is calculated assuming a purchase of shares on the first day and a sale 
       on the last day of each period reported and includes reinvestment of
       dividends and distributions. Total returns for periods of less than a 
       full year are not annualized.
    ## Because of the event referred to in (D)(D) and the timing of such, the 
       ratios for the Class C shares are not necessarily comparable to that of 
       Class A or B shares and are not necessarily indicative of future
       ratios.

See Notes to Financial Statements.
                                      -12-
 <PAGE>
<PAGE>
                          INDEPENDENT AUDITORS' REPORT

The Shareholders and Board of Trustees
Prudential Municipal Series Fund, Maryland Series
   We have audited the statement of assets and liabilities of Prudential
Municipal Series Fund, Maryland Series, including the portfolio of investments,
as of August 31, 1994, the related statements of operations for the year then
ended and of changes in net assets for each of the two years in the period then
ended, and the financial highlights for each of the five years in the period
then ended. These financial statements and financial highlights are the
responsibility of the Fund's management. Our responsibility is to express an
opinion on these financial statements and financial highlights based on our
audits.
   We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements and financial
highlights are free of material misstatement. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements. Our procedures included confirmation of the securities owned as of
August 31, 1994 by correspondence with the custodian. An audit also includes
assessing the accounting principles used and significant estimates made by
management, as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.
   In our opinion, such financial statements and financial highlights present
fairly, in all material respects, the financial position of Prudential Municipal
Series Fund, Maryland Series, as of August 31, 1994, the results of its
operations, the changes in its net assets, and its financial highlights for the
respective stated periods in conformity with generally accepted accounting
principles.

Deloitte & Touche LLP
New York, New York
October 17, 1994

                         FEDERAL INCOME TAX INFORMATION

   We are required by the Internal Revenue Code to advise you within 60 days of
the Series' fiscal year end (August 31, 1994) as to the federal tax status of
dividends paid by the Series during such fiscal year. Accordingly, we are
advising you that in the fiscal year ended August 31, 1994, dividends paid from
net investment income of $.57 per Class A share, $.53 per Class B share and $.05
per Class C share were all federally tax-exempt interest dividends. In addition,
the Series paid to both Class A and B shares a long-term capital gain
distribution of $.144 per share which is taxable as such and a short-term
capital gain distribution of $.068 per share which is taxable as ordinary
income.
   In January 1995, you will be advised on IRS Form 1099 DIV or substitute 1099
DIV as to the federal tax status of the distributions received by you in
calendar year 1994.
                                      -13-
 <PAGE>
<PAGE>

   These graphs are furnished to you in accordance with SEC regulations. They
compare a $10,000 investment in Prudential Municipal Series Fund: Maryland
Series (Class A, Class B, and Class C) with a similar investment in the Lehman
Brothers Municipal Bond Index (the Index) by portraying the initial account
values at the commencement of operations of each class and subsequent account
values at the end of each fiscal year (August 31) beginning in 1990 for Class A,
in 1985 for Class B shares and 1994 for Class C shares. For purposes of the
graphs and, unless otherwise indicated, the accompanying tables, it has been
assumed that
(a) the maximum sales charge was deducted from the initial $10,000 investment in
Class A shares; (b) the maximum applicable contingent deferred sales charge was
deducted from the value of the investment in Class B shares and Class C shares,
assuming full redemption on August 31, 1994; (c) all recurring fees (including
management fees) were deducted; and (d) all dividends and distributions were
reinvested. Class B shares will automatically convert to Class A shares on a
quarterly basis approximately seven years after purchase. This conversion
feature is expected to be implemented on or about February 1995 and is not
reflected in the graph. The graph and accompanying tables reflect the past
subsidy and/or waiver of expenses and/or management fees. Without fee waivers
and expense subsidies, the value of a $10,000 investment in the Series and the
Series' average annual total return, as shown above, would have been lower.
   The Index is a weighted index comprised of 21,000 municipal bonds (general
obligation bonds, revenue bonds, insured bonds and prerefunded bonds) selected
by Lehman Brothers as representative of the long-term investment grade municipal
bond market. The Index is an unmanaged index and includes the reinvestment of
all income, but does not reflect the payment of transaction costs and advisory
fees associated with an investment in the Series. The securities which comprise
the Index may differ substantially from the securities in the Series' portfolio
because the Index, among other things, is not state specific. The Lehman
Brothers Municipal Bond Index is not the only index which may be used to
characterize performance of long-term, investment-grade tax-exempt bond funds
and other indexes may portray different comparative performance.
 <PAGE>
<PAGE>
Trustees
Edward D. Beach
Eugene C. Dorsey
Delayne Dedrick Gold
Harry A. Jacobs, Jr.
Lawrence C. McQuade
Thomas T. Mooney
Thomas H. O'Brien
Richard A. Redeker
Nancy H. Teeters

Officers
Lawrence C. McQuade, President
Robert F. Gunia, Vice President
Susan C. Cote, Treasurer
S. Jane Rose, Secretary
Ronald Amblard, Assistant Secretary
Deborah A. Docs, Assistant Secretary

Manager
Prudential Mutual Fund Management, Inc.
One Seaport Plaza
New York, NY 10292

Investment Adviser
The Prudential Investment Corporation
Prudential Plaza
Newark, NJ 07101

Distributors
Prudential Mutual Fund Distributors, Inc.
Prudential Securities Incorporated
One Seaport Plaza
New York, NY 10292

Custodian
State Street Bank and Trust Company
One Heritage Drive
North Quincy, MA 02171

Transfer Agent
Prudential Mutual Fund Services, Inc.
P.O. Box 15005
New Brunswick, NJ 08906

Independent Accountants
Deloitte & Touche LLP
1633 Broadway
New York, NY 10019

Legal Counsel
Gardner, Carton & Douglas
Quaker Tower
321 North Clark Street
Chicago, IL 60610-4795

Prudential Mutual Funds
One Seaport Plaza
New York, NY 10292
Toll free (800) 225-1852, Collect (908) 417-7555

This report is not authorized for distribution to prospective investors 
unless preceded or accompanied by a current prospectus.

74435M705
74435M804                                          MF 125E
74435M572           (LOGO)                   Cat. #6420828

























































ANNUAL REPORT                     August 31, 1994

Prudential
Municipal
Series Fund

(ICON)

Michigan Series

<PAGE>

Letter to Shareholders

October 18, 1994 

Dear Shareholder:It has been a most difficult year in the U.S. 
financial markets.  When we last wrote in February  interest rates 
were starting to rise, ending a three-year long bull market in bonds. 
What started as a trickle has become a torrent.  Interest rates have 
continued to increase this year, sending bond prices down sharply.  
Of course, as interest rates rise, bond prices decline.  In this 
environment of falling prices and unusual volatility, your Prudential 
Municipal Series Fund -- Michigan Series sought to minimize risk while 
maximizing your tax-free income.

The Series seeks maximum income exempt from Michigan and federal 
income taxes* consistent with preservation of capital.  The portfolio 
is comprised of investment grade municipal obligations with an average 
Aa credit quality as determined by Moody's Investors Service.  
The Series performed in line with the Lipper Michigan Municipal 
Debt Average over the last year, but because long-term interest 
rates rose, total returns were disappointing.  As a result, the Series 
has become more cautious and shortened its average maturity.

<TABLE>
                        SERIES PERFORMANCE 
                       As of August 31, 1994   
<CAPTION>
                         30-day            Taxable Equivalent Yields   
                 NAV    SEC Yield       @28%          @31%        @39.6%
<S>            <C>        <C>           <C>           <C>          <C>
Class A        $11.75     4.6%          6.7%          7.0%         8.0%
Class B        $11.75     4.3%          6.3%          6.6%         7.5% 
Class C        $11.75     N/A           N/A           N/A          N/A
</TABLE>

Investment return and principal value will fluctuate so that an investor's 
shares, when redeemed, may be worth more or less than their original cost.  
Past performance is no guarantee of future results.

*Interest on municipal obligations may be subject to the federal 
alternative minimum tax.  See your Series' prospectus for more details.

                               -1-
<PAGE>
<TABLE>
                             TOTAL RETURNS
<CAPTION>
                    Historical (As of 8/31/94)1      Average Annual (As of 9/30/94)2
                    1-Yr.    5-Yr.  Since Incep.**    1-Yr.   5-Yr. Since Incep.**
<S>                 <C>      <C>     <C>             <C>      <C>     <C>
Class A             -0.4%     N/A     +40.7%         -5.9%    N/A     +6.6%
Class B             -0.8%   +41.5%   +132.1%         -8.5%   +6.8%    +8.6%
Class C              N/A      N/A      +0.1%          N/A     N/A     -2.4%
Lipper MI 
Muni Debt Avg.***   -0.4%   +45.6%   +144.8%          N/A     N/A      N/A
</TABLE>

Source: Lipper Analytical Services, Inc. These figures do not 
take into account sales charges.

2 Source: Prudential Mutual Fund Management, Inc.  These averages take 
into account applicable sales charges.  The Series charges a maximum 
initial sales charge of 3% for Class A shares.  Class B shares are 
subject to a declining contingent deferred sales charge of 5%, 4%, 3%, 
2%, 1% and 1%, respectively, for the first six years.  Class B shares 
will automatically convert to Class A shares approximately seven years 
after purchase.  This conversion feature is expected to be implemented in 
February 1995. Class C shares are subject to a contingent deferred sales 
charge of 1% during the first year. 

**Inception on January 22, 1990 for Class A, and September 22, 1984 
for Class B and August 1, 1994 for Class C.

***These are the average returns of 32 Michigan municipal debt 
funds for one-year, five-year, and since inception of Class B 
shares, as determined by Lipper Analytical Services, Inc.

Once Was Not Enough

When we wrote to you in February, the Federal Reserve raised short-term 
interest rates for the first time in years, hoping to control inflation.  
Since then, the Fed has moved four more times, until the federal funds rate 
(the overnight interbank lending rate) now stands at 4.75%, up from 3% at 
the start of the year.  The Fed also increased the discount rate (at which 
it lends banks money) to 4% from 3% over the same period.

Interest rates rise when the financial markets fear inflation, the bond 
holder's enemy. Inflation is feared because it robs purchasing power 
from a bond's fixed-interest rate.

Municipal bond interest rates increased by more than a percentage 
point, to 6.46% on August 25 from 5.52% on December 29, 1993, as 
measured by the Bond Buyer's Revenue Bond Index, a widely used 
yardstick of interest rates in the tax-free market.

Michigan:  In the Driver's Seat

As the auto industry goes, so goes Michigan.  At present, the state has 
one of the strongest economic growth rates in the country, carried along 
by the auto industry that drives its economy.  But the industry and 
therefore the state's economy are notoriously cyclical. For the short 
term, both have a favorable outlook.  But in the longer term,  the current 
round of  tax cuts and increased spending could weigh the state down in 
the next recession.

                                  -2-

<PAGE>

Clearly the most significant development on the fiscal front was the 
decision to increase state taxes, particularly the sales tax, to replace 
the property taxes that fund the schools.   This will equalize school 
funding across the state, but it will also force the schools to rely 
on a more economically vulnerable source of revenue.

As a result, the state has more to lose in the next recession.  But a 
burgeoning auto industry should carry Michigan until then.  And 
fortunately the state is making payments now into a rainy day fund 
to prepare for its next economic downturn.

We have generally avoided state general obligation and school bonds 
guaranteed by the state during the past several years because of  
Michigan's fiscal condition during the recession.   However, this 
past year Standard & Poor's took Michigan off its 
negative credit watch list, so we are currently looking to buy such 
state-related credits again. 

A Tax Reminder

As a result of the federal Revenue Reconciliation Act of 1993, which 
affects bonds purchased after April 30, 1993,  it is possible that this 
year you may have some taxable income from your tax-free municipal bond 
fund.  The law stipulates that the portion of any gain realized on 
the sale or retirement of a tax-free bond purchased at a market 
discount to its face value must be taxed as ordinary income.

Following this change in federal tax law, some discount bonds have 
been selling at levels so cheap they will produce a higher after-tax 
return than other bonds not subject to the provisions of the new law.  
We have occasionally taken advantage of this market imbalance because 
we have determined that at very low prices these bonds can still provide 
you with a higher after-tax return on your investment.

The Outlook

We expect continued volatility in the municipal bond market until the 
economy reaches a level of growth that is sustainable without causing 
inflation.  If the economy continues to surge, the ever vigilant Fed 
will move again, lifting short-term rates.  If the economy slows 
substantially, long term rates should stabilize.  Although rates 
may keep rising, we believe that most of the increase is now behind us.

In the months ahead, we expect supply -- or the lack of it -- to become 
more important in the tax-free municipal bond market.  Through the first 
eight months of the year, new issue volume is off 42%,  according to 
Securities Data Co., which tracks this statistic.  The pace is 
accelerating.  In August, new issue volume fell 56%.  

                                    -3-

<PAGE>

As always, it is a pleasure to have you as a shareholder in the 
Prudential Municipal Series Fund -- Michigan Series, and to take 
this opportunity to report our activities to you.


Sincerely,


Lawrence C. McQuade
President


Christian Smith
Portfolio Manager

                                -4-

<PAGE>


PRUDENTIAL MUNICIPAL SERIES FUND       Portfolio of Investments
MICHIGAN SERIES                                 August 31, 1994

<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                   Value
(Unaudited)     (000)          Description (a)        (Note 1)
<C>           <C>          <S>                       <C>
                           LONG-TERM INVESTMENTS--98.0%
                           Bay De Noc Comm. Coll.
                             Dist.,
                           4.60%, 5/1/13,
Aaa            $    575      M.B.I.A...............  $   475,146
                           Breitung Twnshp. Sch.
                             Dist. Rev.,
                             Gen. Oblig.,
                           6.30%, 5/1/15,
Aaa                 250      M.B.I.A...............      253,580
                           Canton Charter Twnshp.
                             Bldg. Auth.,
                             Wayne Cnty. Golf
                             Course,
Aaa                 450    4.75%, 1/1/11, F.S.A....      387,693
Aaa                 450    4.75%, 1/1/12, F.S.A....      382,086
Aaa                 500    4.75%, 1/1/13, F.S.A....      421,200
Aaa                 500    4.75%, 1/1/14, F.S.A....      417,450
                           Central Michigan Univ.
                             Rev.,
A                   700(D) 7.00%, 10/1/10..........      784,154
                           Chippewa Valley Sch.
                             Dist.,
                           5.00%, 5/1/21,
Aaa               2,400      F.G.I.C...............    2,015,496
                           Clinton Twnshp. Bldg.
                             Auth.,
                             Macomb Cnty.,
                           4.75%, 11/1/10,
Aaa               2,810      A.M.B.A.C.............    2,423,288
                           Coldwater Wtr. Supply &
                             Wastewater Sys. Rev.,
                           6.125%, 7/1/15,
Aaa                 445      A.M.B.A.C.............      446,624
                           Detroit Econ. Dev.
                             Corp.,
                             Res. Rec. Rev.,
                           6.875%, 5/1/09, Ser. A,
Aaa               1,000      F.S.A.................    1,049,400
                           Detroit Sewage Disp.
                             Rev.,
                           5.70%, 7/1/23,
Aaa               2,000      F.G.I.C...............    1,861,220
                           Detroit St. Aid, Gen.
                             Oblig.,
Baa               1,500    5.625%, 5/1/97..........    1,511,850
                           Detroit Wtr. Supply Sys.
                             Rev.,
                           6.50%, 7/1/15,
Aaa               1,000      F.G.I.C...............    1,051,560
                           7.25%, 7/1/20,
Aaa               1,000(D)   F.G.I.C...............    1,128,070
                           Ferris St. Univ. Gen.
                             Rev.,
                           5.80%, 10/1/05,
Aaa                 440      A.M.B.A.C.............      449,715
                           Grand Rapids San. Swr. Sys. Rev.,
A1                  500    7.00%, 1/1/16...........      535,210
                           Grand Rapids Wtr. Supply
                             Sys. Rev.,
                           7.05%, 1/1/05,
Aaa                 515(D)   F.G.I.C...............      572,525
Aaa               2,100(D) 7.875%, 1/1/18..........    2,335,137
                           Holland Sch. Dist.,
                             A.M.B.A.C.,
Aaa            $  2,400    Zero Coupon, 5/1/15.....  $   654,072
                           Huron Valley Sch. Dist.,
                             Gen. Oblig.,
                           Zero Coupon, 5/1/10,
Aaa               3,500      F.G.I.C...............    1,330,455
                           Kent Hosp. Fac. Fin.
                             Auth. Rev.,
                             Blodgette Mem. Med.
                             Ctr.,
A                   500    7.25%, 7/1/05, Ser. A...      535,295
                           Butterworth Hosp.,
                           7.25%, 1/15/12, Ser.
Aaa                 500(D)   A.....................      559,555
                           Michigan Higher Ed.,
                             Student
                             Loan Auth. Rev.,
                             M.B.I.A.,
                           7.55%, 10/1/08, Ser.
Aaa                 500      XIII-A................      538,515
                           Michigan Mun. Bond Auth.
                             Rev.,
                             Local Gov't. Loan
                             Prog.,
AAA*                500(D) 7.80%, 5/1/13...........      565,005
                           Michigan Pub. Pwr. Agcy.
                             Rev.,
                             Belle River Proj.,
A1                1,250    5.25%, 1/1/18, Ser. A...    1,085,050
                           Michigan St. Comp.
                             Trans. Rev.,
                           5.875%, 5/15/05, Ser.
A1                1,250      B.....................    1,287,612
                           Michigan St. Hosp. Fin. Auth. Rev.,
                             Bay Med. Ctr.,
Baa1              2,000    8.25%, 7/1/12, Ser. A...    2,160,480
                           McLaren Obligated Group,
                           7.50%, 9/15/21, Ser.
Aaa                 800(D)   A.....................      924,576
                           Oakwood Hosp. Obligated Group,
                           6.95%, 7/1/02,
Aaa               1,000(D)@   F.G.I.C...............   1,113,590
                           Sisters of Mercy,
                             M.B.I.A.,
                           7.50%, 8/15/07, Ser.
Aaa               2,000      H.....................    2,191,640
                           Michigan St. Hsg. Dev. Auth. Rev.,
                             Multifamily Mtge. Insured Hsg.,
A+*               1,000    7.15%, 4/1/10, Ser. A...    1,033,520
                           8.875%, 7/1/17, Ser. A,
Aaa               1,000@@    F.G.I.C...............    1,052,360
A*                  500    7.70%, 4/1/23, Ser. A...      520,615
                           Sngl. Fam. Mtge.,
                           7.70%, 12/1/16, Ser.
AA*                 445      A.....................      462,907
</TABLE>
 
                                      -5-     See Notes to Financial Statements.
 <PAGE>
<PAGE>

PRUDENTIAL MUNICIPAL SERIES FUND
MICHIGAN SERIES

<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                   Value
(Unaudited)     (000)          Description (a)        (Note 1)
<C>           <C>          <S>                       <C>
                           Michigan St. Strategic
                             Fund Ltd. Obligated
                             Rev., Waste Mgmt. Inc.
                             Proj.,
A1             $  2,000    6.625%, 12/1/12.........  $ 2,022,680
                           Michigan St. Trunk Line
                             Hwy.,
                           7.00%, 8/15/17, Ser.
AAA*              2,000(D)   A.....................    2,214,200
                           Ser. A, A.M.B.A.C.,
Aaa               2,600    Zero Coupon, 10/1/05....    1,391,572
Aaa               1,250    Zero Coupon, 10/1/06....      622,750
                           Monroe Cnty. Poll. Ctrl.
                             Rev.,
                             Detroit Edison Co.,
                           10.50%, 12/1/16, Ser.
Baa1              1,500      A.....................    1,653,270
                           7.65%, 9/1/20,
Aaa               2,000      F.G.I.C...............    2,213,600
                           Mt. Pleasant Wtr. Rev.,
                             Wtr. & Swr., M.B.I.A.,
Aaa                 485    6.00%, 2/1/21...........      476,149
Aaa                 520    5.00%, 2/1/22...........      435,807
Aaa                 550    4.00%, 2/1/23...........      383,630
Aaa                 585    4.00%, 2/1/24...........      405,844
                           Oak Park, Gen. Oblig.,
                           7.00%, 5/1/11,
Aaa                 375(D)   A.M.B.A.C.............      421,751
                           7.00%, 5/1/12,
Aaa                 400(D)   A.M.B.A.C.............      449,868
                           Oakland Cnty., City of Lathrup,
                             Evergreen Farmington Swr. Rev.,
A                   600    6.00%, 11/1/08..........      607,170
A                   700    6.00%, 11/1/09..........      701,120
                           Oakland Cnty., Leuders
                             Drainage Dept.,
                           5.50%, 5/1/09,
Aaa                 350      A.M.B.A.C.............      337,684
                           Ottawa Cnty., Gen. Oblig.,
                             Northwest Ottawa Wtr. Supply,
A1                  415    6.25%, 10/1/08..........      423,794
                           Wtr. Supply Sys.,
NR                1,045(D) 7.60%, 8/1/07...........    1,125,998
                           Pinckney Comm. Sch.,
                             Livingston & Washtenaw
                             Cntys.,
                           5.00%, 5/1/14,
Aaa               1,250      F.G.I.C...............    1,080,750
                           Puerto Rico Elec. Pwr.
                             Auth. Rev.,
                           7.125%, 7/1/14, Ser.
Baa1              1,580(D)   N.....................    1,756,913
                           7.125%, 7/1/14, Ser.
Baa1                920      N.....................      983,112
                           Puerto Rico Commonwlth.
                             Hwy. Auth. Rev.,
Baa1           $  1,000    6.75%, 7/1/05, Ser. R...  $ 1,088,150
Baa1              1,500(D)@ 7.75%, 7/1/16, Ser. Q...   1,738,755
                           Puerto Rico Pub. Bldgs.
                             Auth.,
                             Gtd. Pub. Ed. & Hlth.
                             Facs.,
Baa1                625(D) 8.00%, 7/1/12, Ser. F...      681,119
                           6.875%, 7/1/21, Ser.
Aaa               1,325(D)@   L.....................   1,490,399
                           Pub. Ed. & Hlth. Facs.,
                           7.875%, 7/1/16, Ser.
Aaa                 990(D)   H.....................    1,095,871
                           Puerto Rico, Gen.
                             Oblig.,
                           8.34%, 7/1/08, Ser. A,
Aaa               1,000(D)(D)   M.B.I.A...............   1,012,500
                           Saginaw Valley St. Univ. Gen. Rev.,
                           5.375%, 7/1/16,
Aaa                 790      M.B.I.A...............      717,778
                           Saline Area Sch. Dist.,
                           5.00%, 5/1/04, Ser. 1,
Aaa                 700      M.B.I.A...............      680,344
                           Tri-Cnty. Area Schs., Gen. Oblig.,
                           5.25%, 5/1/20,
Aaa               2,000      F.G.I.C...............    1,750,360
                           Univ. of Michigan Major
                             Cap. Proj. Rev.,
Aa1                 355    5.50%, 4/1/13...........      328,148
                           Univ. of Michigan Rev.,
                           5.50%, 8/15/22, Ser.
A1                  640      A.....................      569,990
                           Pkg. Sys. Rfdg.,
Aa                  500    5.00%, 6/1/15...........      427,320
                           Virgin Islands Pub. Fin. Auth. Rev.,
                             Matching Loan Notes,
                           7.25%, 10/1/18, Ser.
NR                  500      A.....................      515,810
                           Virgin Islands Wtr. &
                             Pwr. Auth.,
                             Elec. Sys. Rev.,
NR                  500    7.40%, 7/1/11, Ser. A...      522,300
                           Wtr. Sys. Rev.,
NR                  500    8.50%, 1/1/10, Ser. A...      549,280
                           Wayne Cnty. Arpt. Rev.,
                           6.125%, 12/1/24,
Aaa                 500      M.B.I.A...............      488,830
                           Wayne Cnty. Bldg. Auth.,
Baa               1,250(D) 8.00%, 3/1/17, Ser. A...    1,466,725
                           Western Michigan Univ. Gen. Rev.,
                           5.00%, 7/15/21,
Aaa                 500      F.G.I.C...............      417,955
</TABLE>
 
                                      -6-     See Notes to Financial Statements.
 <PAGE>
<PAGE>

PRUDENTIAL MUNICIPAL SERIES FUND
MICHIGAN SERIES

<TABLE>
<CAPTION>
  Moody's     Principal
  Rating       Amount                                  Value
(Unaudited)     (000)          Description (a)        (Note 1)
<S>           <C>          <C>                       <C>
                           Wixom, Gen. Oblig.,
                           6.00%, 4/1/07,
Aaa            $    475      A.M.B.A.C.............  $   486,785
                           6.00%, 4/1/08,
Aaa                 475      A.M.B.A.C.............      482,918
                           6.00%, 4/1/09,
Aaa                 500      A.M.B.A.C.............      503,840
                           Wyandotte Elec. Rev.,
                           6.25%, 10/1/08,
Aaa               2,000      M.B.I.A...............    2,089,580
                                                     -----------
                           Total Investments--98.0%
                           (cost $70,069,806; Note
                             4)....................   73,329,070
                           Other assets in excess
                             of
                             liabilities--2.0%.....    1,489,587
                                                     -----------
                           Net Assets--100%........  $74,818,657
                                                     -----------
                                                     -----------
</TABLE>
 
- ------------------
(a) The following abbreviations are used in portfolio descriptions:
    A.M.B.A.C.--American Municipal Bond Assurance
    Corporation.
    F.G.I.C.--Financial Guaranty Insurance Company.
    F.S.A.--Financial Security Assurance.
    M.B.I.A.--Municipal Bond Insurance Association.

   * Standard & Poor's rating.
 (D) Prerefunded issues are secured by escrowed cash
     and/or
     direct U.S. guaranteed obligations.
(D)(D) Inverse floating rate bond. The coupon is
     inversely indexed to a floating interest rate.
     The rate shown is the rate at period end.
   @ Pledged as initial margin on financial futures
     contracts.
  @@ $600,000 par amount pledged as initial margin on
     financial futures contracts.

NR--Not Rated by Moody's or Standard & Poor's.
The Fund's current Statement of Additional Information contains a description of
Moody's and Standard & Poor's ratings.

                                      -7-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 MICHIGAN SERIES
 Statement of Assets and Liabilities
<TABLE>
<CAPTION>
Assets                                                                                      August 31, 1994
                                                                                            ---------------
<S>                                                                                         <C>
Investments, at value (cost $70,069,806).................................................     $73,329,070
Cash.....................................................................................         260,847
Interest receivable......................................................................       1,113,789
Receivable for investments sold..........................................................         515,000
Receivable for Fund shares sold..........................................................         166,692
Other assets.............................................................................           1,963
                                                                                            ---------------
  Total assets...........................................................................      75,387,361
                                                                                            ---------------
Liabilities
Payable for Fund shares reacquired.......................................................         369,954
Accrued expenses.........................................................................          72,343
Dividends payable........................................................................          54,835
Management fee payable...................................................................          31,648
Distribution fee payable.................................................................          30,065
Due to broker-variation margin payable...................................................           8,849
Deferred trustee fees....................................................................           1,010
                                                                                            ---------------
  Total liabilities......................................................................         568,704
                                                                                            ---------------
Net Assets...............................................................................     $74,818,657
                                                                                            ---------------
                                                                                            ---------------
Net assets were comprised of:
  Shares of beneficial interest, at par..................................................     $    63,681
  Paid-in capital in excess of par.......................................................      71,608,322
                                                                                            ---------------
                                                                                               71,672,003
  Distributions in excess of net realized gains..........................................         (56,985)
  Net unrealized appreciation of investments.............................................       3,203,639
                                                                                            ---------------
  Net assets, August 31, 1994............................................................     $74,818,657
                                                                                            ---------------
                                                                                            ---------------
Class A:
  Net asset value and redemption price per share ($4,706,290 / 400,422 shares of
    beneficial
    interest issued and outstanding).....................................................          $11.75
  Maximum sales charge (3.0% of offering price)..........................................             .36
                                                                                            ---------------
  Maximum offering price to public.......................................................          $12.11
                                                                                            ---------------
                                                                                            ---------------
Class B:
  Net asset value, offering price and redemption price per share ($70,112,167 / 5,967,688
    shares of beneficial interest issued and outstanding)................................          $11.75
                                                                                            ---------------
                                                                                            ---------------
Class C:
  Net asset value, offering price and redemption price per share ($199.71 / 17 shares of
    beneficial
    interest issued and outstanding).....................................................          $11.75
                                                                                            ---------------
                                                                                            ---------------
</TABLE>
 
See Notes to Financial Statements.
                                      -8-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 MICHIGAN SERIES
 Statement of Operations
<TABLE>
<CAPTION>
                                          Year Ended
                                          August 31,
Net Investment Income                        1994
                                          ----------
<S>                                       <C>
Income
  Interest.............................   $4,738,679
                                          ----------
Expenses
  Management fee.......................      383,005
  Distribution fee--Class A............        4,506
  Distribution fee--Class B............      360,476
  Custodian's fees and expenses........       87,000
  Transfer agent's fees and expenses...       63,000
  Registration fees....................       31,500
  Reports to shareholders..............       23,000
  Legal fees...........................       15,000
  Audit fee............................       10,500
  Trustees' fees.......................        3,375
  Miscellaneous........................        5,006
                                          ----------
    Total expenses.....................      986,368
                                          ----------
Net investment income..................    3,752,311
                                          ----------
Realized and Unrealized
Gain (Loss) on Investments
Net realized gain on:
  Investment transactions..............      307,651
  Financial futures contract
  transactions.........................      147,685
                                          ----------
                                             455,336
                                          ----------
Net change in unrealized
  appreciation/depreciation of:
  Investments..........................   (4,881,251)
  Financial futures contracts..........      (36,562)
                                          ----------
                                          (4,917,813)
                                          ----------
Net loss on investments................   (4,462,477)
                                          ----------
Net Decrease in Net Assets
Resulting from Operations..............   $ (710,166)
                                          ----------
                                          ----------
</TABLE>
 
 PRUDENTIAL MUNICIPAL SERIES FUND
 MICHIGAN SERIES
 Statement of Changes in Net Assets
<TABLE>
<CAPTION>
                               Year Ended August 31,
Increase (Decrease)          --------------------------
in Net Assets                   1994           1993
                             -----------    -----------
<S>                          <C>            <C>
Operations
  Net investment income....  $ 3,752,311    $ 3,273,879
  Net realized gain on
    investment
    transactions...........      455,336         72,559
  Net change in unrealized
  appreciation/depreciation
    of investments.........   (4,917,813)     3,763,379
                             -----------    -----------
  Net increase (decrease)
    in net assets resulting
    from operations........     (710,166)     7,109,817
                             -----------    -----------
Dividends and distributions (Note 1):
  Dividends from net
    investment income
    Class A................     (237,966)      (125,767)
    Class B................   (3,514,345)    (3,148,112)
                             -----------    -----------
                              (3,752,311)    (3,273,879)
                             -----------    -----------
  Distributions from net
    realized gains
    Class A................      (25,697)       (15,062)
    Class B................     (429,245)      (460,116)
                             -----------    -----------
                                (454,942)      (475,178)
                             -----------    -----------
Series share transactions
  (Note 5):
  Net proceeds from shares
    sold...................   13,225,456     16,968,562
  Net asset value of shares
    issued in reinvestment
    of dividends and
    distributions..........    2,730,066      2,426,469
  Cost of shares
  reacquired...............  (10,334,965)    (6,352,793)
                             -----------    -----------
  Net increase in net
    assets from Series
    share transactions.....    5,620,557     13,042,238
                             -----------    -----------
Total increase.............      703,138     16,402,998
Net Assets
Beginning of year..........   74,115,519     57,712,521
                             -----------    -----------
End of year................  $74,818,657    $74,115,519
                             -----------    -----------
                             -----------    -----------
</TABLE>
 
See Notes to Financial Statements.
                                      -9-
<PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 MICHIGAN SERIES
 Notes to Financial Statements
   Prudential Municipal Series Fund (the ``Fund'') is registered under the
Investment Company Act of 1940, as an open-end investment company. The Fund was
organized as a Massachusetts business trust on May 18, 1984 and consists of
seventeen series. The monies of each series are invested in separate,
independently managed portfolios. The Michigan Series (the ``Series'') commenced
investment operations in September, 1984. The Series is diversified and seeks to
achieve its investment objective of obtaining the maximum amount of income
exempt from federal and applicable state income taxes with the minimum of risk
by investing in ``investment grade'' tax-exempt securities whose ratings are
within the four highest ratings categories by a nationally recognized
statistical rating organization or, if not rated, are of comparable quality. The
ability of the issuers of the securities held by the Series to meet their
obligations may be affected by economic or political developments in a specific
state, industry or region.

Note 1. Accounting            The following is a summary
Policies                      of significant accounting poli-
                              cies followed by the Fund, and the Series, in the
preparation of its financial statements.
Securities Valuations: The Fund values municipal securities (including
commitments to purchase such securities on a ``when-issued'' basis) on the basis
of prices provided by a pricing service which uses information with respect to
transactions in bonds, quotations from bond dealers, market transactions in
comparable securities and various relationships between securities in
determining values. If market quotations are not readily available from such
pricing service, a security is valued at its fair value as determined under
procedures established by the Trustees.
   Short-term securities which mature in more than 60 days are valued at current
market quotations. Short-term securities which mature in 60 days or less are
valued at amortized cost.
   All securities are valued as of 4:15 P.M., New York time.
Financial Futures Contracts: A financial futures contract is an agreement to
purchase (long) or sell (short) an agreed amount of debt securities at a set
price for delivery on a future date. Upon entering into a financial futures
contract, the Series is required to pledge to the broker an amount of cash
and/or other assets equal to a certain percentage of the contract amount. This
amount is known as the ``initial margin''. Subsequent payments, known as
``variation margin'', are made or received by the Series each day, depending on
the daily fluctuations in the value of the underlying security. Such variation
margin is recorded for financial statement purposes on a daily basis as
unrealized gain or loss. The Series invests in financial futures contracts
solely for the purpose of hedging it's existing portfolio securities or
securities the Series intends to purchase against fluctuations in value caused
by changes in prevailing market conditions. Should market conditions move
unexpectedly, the Series may not achieve the anticipated benefits of the
financial futures contracts and may realize a loss. The use of futures
transactions involves the risk of imperfect correlation in movements in the
price of futures contracts, interest rates and the underlying hedged assets.
Securities Transactions and Investment Income: Securities transactions are
recorded on the trade date. Realized gains and losses on sales of securities are
calculated on the identified cost basis. Interest income is recorded on the
accrual basis. The Series amortizes premiums and original issue discount paid on
purchases of portfolio securities as adjustments to interest income.
   Net investment income (other than distribution fees) and unrealized and
realized gains or losses are allocated daily to each class of shares based upon
the relative proportion of net assets of each class at the beginning of the day.
Federal Income Taxes: For federal income tax purposes, each series in the Fund
is treated as a separate taxpaying entity. It is the intent of the Series to
continue to meet the requirements of the Internal Revenue Code applicable to
regulated investment companies and to distribute all of its net income to
shareholders. For this reason and because substantially all of the Series' gross
income consists of tax-exempt interest, no federal income tax provision is
required.

Dividends and Distributions: The Series declares daily dividends from net
investment income. Payment of dividends is made monthly. Distributions of net
capital gains, if any, are made annually.
   Income distributions and capital gain distributions are determined in
accordance with income tax regulations which may differ from generally accepted
accounting principles.

Note 2. Agreements            The Fund has a management
                              agreement with Prudential Mutual Fund Management,
Inc. (``PMF''). Pursuant to this
                                      -10-
<PAGE>
<PAGE>
agreement, PMF has responsibility for all investment advisory services and
supervises the subadviser's performance of such services. PMF has entered into a
subadvisory agreement with The Prudential Investment Corporation (``PIC''). PIC
furnishes investment advisory services in connection with the management of the
Fund. PMF pays for the services of PIC, the cost of compensation of officers of
the Fund, occupancy and certain clerical and bookkeeping costs of the Fund. The
Fund bears all other costs and expenses.
   The management fee paid PMF is computed daily and payable monthly, at an
annual rate of .50 of 1% of the average daily net assets of the Series.
   The Fund has distribution agreements with Prudential Mutual Fund
Distributors, Inc. (``PMFD''), which acts as the distributor of the Class A
shares of the Fund, and with Prudential Securities Incorporated (``PSI''), which
acts as distributor of the Class B and Class C shares of the Fund (collectively
the ``Distributors''). The Fund compensates the Distributors for distributing
and servicing the Fund's Class A, Class B and Class C shares, pursuant to plans
of distribution (the ``Class A, B and C Plans''), regardless of expenses
actually incurred by them. The distribution fees are accrued daily and payable
monthly.
   On July 19, 1994, shareholders of the Fund approved amendments to the Class A
and Class B distribution plans under which the distribution plans became
compensation plans, effective August 1, 1994. Prior thereto, the distribution
plans were reimbursement plans, under which PMFD and PSI were reimbursed for
expenses actually incurred by them up to the amount permitted under the Class A
and Class B Plans, respectively. The Fund is not obligated to pay any prior or
future excess distribution costs (costs incurred by the Distributors in excess
of distribution fees paid by the Fund or contingent deferred sales charges
received by the Distributors). The rate of the distribution fees charged to
Class A and Class B shares of the Fund did not change under the amended plans of
distribution. The Fund began offering Class C shares on August 1, 1994.
   Pursuant to the Class A, B and C Plans, the Fund compensates the Distributors
for distribution-related activities at an annual rate of up to .30 of 1%, .50 of
1% and 1%, of the average daily net assets of the Class A, B and C shares,
respectively. Such expenses under the Plans were .10 of 1%, .50 of 1% and .75 of
1% of the average daily net assets of the Class A, B and C shares, respectively,
for the fiscal year ended August 31, 1994.
   PMFD has advised the Series that it has received approximately $47,900 in
front-end sales charges resulting from sales of Class A shares during the fiscal
year ended August 31, 1994. From these fees, PMFD paid such sales charges to PSI
and Pruco Securities Corporation, affiliated broker-dealers, which in turn paid
commissions to salespersons and incurred other distribution costs.
   PSI has advised the Series that for the fiscal year ended August 31, 1994, it
received approximately $95,800 in contingent deferred sales charges imposed upon
certain redemptions by Class B shareholders.
   PMFD is a wholly-owned subsidiary of PMF; PSI, PMF and PIC are indirect,
wholly-owned subsidiaries of The Prudential Insurance Company of America.

Note 3. Other                 Prudential Mutual Fund Ser-
Transactions with             vices, Inc. (``PMFS''), a 
Affiliates                    wholly-owned subsidiary of 
                              PMF, serves as the Fund's transfer agent. During
the fiscal year ended August 31, 1994, the Series incurred fees of approximately
$40,500 for the services of PMFS. As of August 31, 1994, approximately $3,300 of
such fees were due to PMFS. Transfer agent fees and expenses in the Statement of
Operations include certain out-of-pocket expenses paid to non-affiliates.

Note 4. Portfolio             Purchases and sales of port-
Securities                    folio securities of the Series, 
                              excluding short-term investments, for the fiscal
year ended August 31, 1994 were $14,305,165 and $9,274,453, respectively.
   At August 31, 1994, the Fund sold 45 financial futures contracts on the
Municipal Bond Index which expire in September, 1994. The value at disposition
of such contracts is $4,611,719. The value of such contracts on August 31, 1994
was $4,667,344, thereby resulting in an unrealized loss of $55,625.
   The cost basis of investments for federal income tax purposes is
substantially the same as for financial reporting purposes and, accordingly, as
of August 31, 1994, net unrealized appreciation for federal income tax purposes
was $3,259,264 (gross unrealized appreciation--$4,534,256; gross unrealized
depreciation--$1,274,992).

Note 5. Capital               The Series currently offers
                              Class A, Class B and Class C shares. Class A
shares are sold with a front-end sales charge of up to 3.0%. Class B shares are
sold with a contingent deferred sales charge which declines from 5% to zero
depending on the period of time the shares are held. Class C shares are sold
with a contingent deferred sales charge of 1% during the first year. Class B
shares will automatically convert to Class A shares on a quarterly basis
approximately seven years after purchase commencing in or about February 1995.
                                      -11-

<PAGE>
   The Fund has authorized an unlimited number of shares of beneficial interest
of each class at $.01 par value per share. Transactions in shares of beneficial
interest for the fiscal years ended August 31, 1994 and 1993 were as follows:
<TABLE>
<CAPTION>
Class A                              Shares        Amount
- ---------------------------------   ---------    -----------
<S>                                 <C>          <C>
Year ended August 31, 1994:
Shares sold......................     125,287    $ 1,540,765
Shares issued in reinvestment of
  dividends and distributions....      14,526        176,113
Shares reacquired................     (44,147)      (531,472)
                                    ---------    -----------
Net increase in shares
  outstanding....................      95,666    $ 1,185,406
                                    ---------    -----------
                                    ---------    -----------

Year ended August 31, 1993:
Shares sold......................     184,780    $ 2,261,702
Shares issued in reinvestment of
  dividends and distributions....       7,339         88,939
Shares reacquired................     (23,307)      (285,030)
                                    ---------    -----------
Net increase in shares
  outstanding....................     168,812    $ 2,065,611
                                    ---------    -----------
                                    ---------    -----------

Year ended August 31, 1994:
Shares sold.....................     953,569    $11,684,491
Shares issued in reinvestment of
  dividends and distributions...     210,536      2,553,953
Shares reacquired...............    (816,504)    (9,803,493)
                                   ---------    -----------
Net increase in shares
  outstanding...................     347,601    $ 4,434,951
                                   ---------    -----------
                                   ---------    -----------
Year ended August 31, 1993:
Shares sold.....................   1,212,261    $14,706,860
Shares issued in reinvestment of
  dividends and distributions...     193,681      2,337,530
Shares reacquired...............    (501,158)    (6,067,763)
                                   ---------    -----------
Net increase in shares
  outstanding...................     904,784    $10,976,627
                                   ---------    -----------
                                   ---------    -----------
 
Class C
- --------------------------------
August 1, 1994* through
  August 31, 1994:
Shares sold.....................          17    $       200
                                   ---------    -----------
Net increase in shares
  outstanding...................          17    $       200
                                   ---------    -----------
                                   ---------    -----------
- ---------------
* Commencement of offering of Class C shares.
</TABLE>
                                      -12-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 MICHIGAN SERIES
 Financial Highlights

<TABLE>
<CAPTION>
                                                         Class A
                                 -------------------------------------------------------               Class B
                                                                             January 22,   --------------------------------
                                                                               1990(D)
                                           Year Ended August 31,               through          Year Ended August 31,
PER SHARE OPERATING              -----------------------------------------   August 31,    --------------------------------
  PERFORMANCE:                       1994        1993       1992     1991       1990           1994        1993      1992
                                 ------------   ------     ------   ------   -----------   ------------   -------   -------
<S>                              <C>            <C>        <C>      <C>      <C>           <C>            <C>       <C>
Net asset value, beginning of
  period......................      $12.51      $11.90     $11.30   $10.81     $ 11.02       $  12.51     $ 11.90   $ 11.30
                                    ------      ------     ------   ------   -----------   ------------   -------   -------

Income from investment
  operations
Net investment income.........         .64         .67        .68      .67         .41            .59         .62       .63
Net realized and unrealized
  gain (loss) on investment
  transactions................        (.69)        .71        .60      .49        (.21)          (.69)        .71       .60
                                    ------      ------     ------   ------   -----------   ------------   -------   -------

  Total from investment
    operations................        (.05)       1.38       1.28     1.16         .20           (.10)       1.33      1.23
                                    ------      ------     ------   ------   -----------   ------------   -------   -------

Less distributions
Dividends from net investment
  income......................        (.64)       (.67)      (.68)    (.67)       (.41)          (.59)       (.62)     (.63)
Distributions from net
  realized gains..............        (.07)       (.10)        --       --          --           (.07)       (.10)       --
                                    ------      ------     ------   ------   -----------   ------------   -------   -------

  Total distributions.........        (.71)       (.77)      (.68)    (.67)       (.41)          (.66)       (.72)     (.63)
                                    ------      ------     ------   ------   -----------   ------------   -------   -------

Net asset value, end of
  period......................      $11.75      $12.51     $11.90   $11.30     $ 10.81       $  11.75     $ 12.51   $ 11.90
                                    ------      ------     ------   ------   -----------   ------------   -------   -------
                                    ------      ------     ------   ------   -----------   ------------   -------   -------

TOTAL RETURN#:................       (0.38)%     11.95%     11.63%   11.04%       1.82%         (0.78)%     11.51%    11.18%
RATIOS/SUPPLEMENTAL DATA:
Net assets, end of period
  (000).......................      $4,706      $3,814     $1,618   $  835     $   501       $ 70,112     $70,302   $56,095
Average net assets (000)......      $4,505      $2,285     $1,235   $  694     $   365       $ 72,095     $61,548   $52,137
Ratios to average net assets:##
  Expenses, including
    distribution fees.........         .91%        .96%@      .98%    1.09%       1.09%*         1.31%       1.36%@    1.38%
  Expenses, excluding
    distribution fees.........         .81%        .86%@      .88%     .99%        .99%*          .81%        .86%@     .88%
  Net investment income.......        5.27%       5.51%@     5.82%    6.09%       6.25%*         4.87%       5.11%@    5.42%
Portfolio turnover............          12%         14%        30%      62%         55%            12%         14%       30%
</TABLE>

<TABLE>
<CAPTION>
                                                     Class C
                                                    ----------
                                                    August 1,
                                                    1994(D)(D)
                                                     through
PER SHARE OPERATING                                 August 31,
  PERFORMANCE:                   1991      1990        1994
                                -------   -------   ----------
<S>                             <C>       <C>       <C>
Net asset value, beginning of
  period......................  $ 10.81   $ 11.03    $  11.78
 
                                -------   -------   ----------
Income from investment
  operations
Net investment income.........      .63       .65         .04
Net realized and unrealized
  gain (loss) on investment
  transactions................      .49      (.22)       (.03)
 
                                -------   -------   ----------
  Total from investment
    operations................     1.12       .43         .01
 
                                -------   -------   ----------
Less distributions
Dividends from net investment
  income......................     (.63)     (.65)       (.04)
Distributions from net
  realized gains..............       --        --          --
 
                                -------   -------   ----------
  Total distributions.........     (.63)     (.65)       (.04)
 
                                -------   -------   ----------
Net asset value, end of
  period......................  $ 11.30   $ 10.81    $  11.75
 
                                -------   -------   ----------
                                -------   -------   ----------
TOTAL RETURN#:................    10.60%     4.02%       0.06%
RATIOS/SUPPLEMENTAL DATA:
Net assets, end of period
  (000).......................  $59,400   $49,923    $    200@@
Average net assets (000)......  $50,809   $48,694    $    199@@
Ratios to average net assets:##
  Expenses, including
    distribution fees.........     1.49%     1.44%       2.15%*
  Expenses, excluding
    distribution fees.........      .99%      .97%       1.39%*
  Net investment income.......     5.66%     5.95%       4.56%*
Portfolio turnover............       62%       55%         12%

 
- ---------------
   * Annualized.
 (D) Commencement of offering of Class A shares.
(D)(D) Commencement of offering of Class C shares.
   # Total return does not consider the effects of sales loads. Total return is calculated assuming a purchase
     of shares on the first day and a sale on the last day of each period reported and includes reinvestment
     of dividends and distributions. Total returns for periods of less than a full year are not annualized.
  ## Because of the event referred to in (D)(D) and the timing of such, the ratios for the Class C shares are
     not necessarily comparable to that of Class A or B shares and are not necessarily indicative of future
     ratios.
   @ Restated.
  @@ Figures are actual and not rounded to the nearest thousand.
</TABLE>
 
See Notes to Financial Statements.
                                      -13-
 <PAGE>
<PAGE>
                          INDEPENDENT AUDITORS' REPORT
The Shareholders and Board of Trustees
Prudential Municipal Series Fund, Michigan Series
   We have audited the accompanying statement of assets and liabilities of
Prudential Municipal Series Fund, Michigan Series, including the portfolio of
investments, as of August 31, 1994, the related statements of operations for the
year then ended and of changes in net assets for each of the two years in the
period then ended, and the financial highlights for each of the five years in
the period then ended. These financial statements and financial highlights are
the responsibility of the Fund's management. Our responsibility is to express an
opinion on these financial statements and financial highlights based on our
audits.
   We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements and financial
highlights are free of material misstatement. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements. Our procedures included confirmation of the securities owned as of
August 31, 1994 by correspondence with the custodian and brokers; where replies
were not received from brokers, we performed other auditing procedures. An audit
also includes assessing the accounting principles used and significant estimates
made by management, as well as evaluating the overall financial statement
presentation. We believe that our audits provide a reasonable basis for our
opinion.
   In our opinion, such financial statements and financial highlights present
fairly, in all material respects, the financial position of Prudential Municipal
Series Fund, Michigan Series, as of August 31, 1994, the results of its
operations, the changes in its net assets, and its financial highlights for the
respective stated periods in conformity with generally accepted accounting
principles.


Deloitte & Touche LLP
New York, New York
October 17, 1994


                         FEDERAL INCOME TAX INFORMATION
   We are required by the Internal Revenue Code to advise you within 60 days of
the Series' fiscal year end (August 31, 1994) as to the federal tax status of
dividends paid by the Series during such fiscal year. Accordingly, we are
advising you that in the fiscal year ended August 31, 1994, dividends paid from
net investment income of $.64 per Class A share, $.59 per Class B share and $.04
per Class C shares were all federally tax-exempt interest dividends. In
addition, the Series paid to both Class A and B shares a long-term capital gain
distribution of $.051 per share which is taxable as such and a short-term
capital gain distribution of $.023 per share which is taxable as ordinary
income.
   In January 1995, you will be advised on IRS Form 1099 DIV or substitute 1099
DIV as to the federal tax status of the distributions received by you in
calendar year 1994.
                                      -14-
 <PAGE>
<PAGE>
   These graphs are furnished to you in accordance with SEC regulations. They
compare a $10,000 investment in Prudential Municipal Series Fund: Michigan
Series (Class A, Class B, and Class C) with a similar investment in the Lehman
Brothers Municipal Bond Index (the Index) by portraying the initial account
values at the commencement of operations of each class and subsequent account
values at the end of each fiscal year (August 31) beginning in 1990 for Class A,
in 1984 for Class B shares and 1994 for Class C shares. For purposes of the
graphs and, unless otherwise indicated, the accompanying tables, it has been
assumed that
(a) the maximum sales charge was deducted from the initial $10,000 investment in
Class A shares; (b) the maximum applicable contingent deferred sales charge was
deducted from the value of the investment in Class B shares and Class C shares,
assuming full redemption on August 31, 1994; (c) all recurring fees (including
management fees) were deducted; and (d) all dividends and distributions were
reinvested. Class B shares will automatically convert to Class A shares on a
quarterly basis approximately seven years after purchase. This conversion
feature is expected to be implemented on or about February 1995 and is not
reflected in the graph. The graph and accompanying tables reflect the past
subsidy and/or waiver of expenses and/or management fees. Without fee waivers
and expense subsidies, the value of a $10,000 investment in the Series and the
Series' average annual total return, as shown above, would have been lower.
   The Index is a weighted index comprised of 21,000 municipal bonds (general
obligation bonds, revenue bonds, insured bonds and prerefunded bonds) selected
by Lehman Brothers as representative of the long-term investment grade municipal
bond market. The Index is an unmanaged index and includes the reinvestment of
all income, but does not reflect the payment of transaction costs and advisory
fees associated with an investment in the Series. The securities which comprise
the Index may differ substantially from the securities in the Series' portfolio
because the Index, among other things, is not state specific. The Lehman
Brothers Municipal Bond Index is not the only index which may be used to
characterize performance of long-term, investment-grade tax-exempt bond funds
and other indexes may portray different comparative performance.

                                      -15-

<PAGE>

Trustees
Edward D. Beach
Eugene C. Dorsey
Delayne Dedrick Gold
Harry A. Jacobs, Jr.
Lawrence C. McQuade
Thomas T. Mooney
Thomas H. O'Brien
Richard A. Redeker
Nancy H. Teeters

Officers
Lawrence C. McQuade, President
Robert F. Gunia, Vice President
Susan C. Cote, Treasurer
S. Jane Rose, Secretary
Ronald Amblard, Assistant Secretary
Deborah A. Docs, Assistant Secretary

Manager
Prudential Mutual Fund Management, Inc.
One Seaport Plaza
New York, NY 10292

Investment Adviser
The Prudential Investment Corporation
Prudential Plaza
Newark, NJ 07101

Distributors
Prudential Mutual Fund Distributors, Inc.
Prudential Securities Incorporated
One Seaport Plaza
New York, NY 10292

Custodian
State Street Bank and Trust Company
One Heritage Drive
North Quincy, MA 02171

Transfer Agent
Prudential Mutual Fund Services, Inc.
P.O. Box 15005
New Brunswick, NJ 08906

Independent Accountants
Deloitte & Touche LLP
1633 Broadway
New York, NY 10019

Legal Counsel
Gardner, Carton & Douglas
Quaker Tower
321 North Clark Street
Chicago, IL 60610-4795

Prudential Mutual Funds
One Seaport Plaza
New York, NY 10292

Toll free (800) 225-1852, Collect (908) 417-7555

This report is not authorized for distribution to 
prospective investors unless preceded or 
accompanied by a current prospectus.

74435M671 
74435M689                           MF 120E
74435M556          (LOGO)      Cat. #6427410



















ANNUAL REPORT                            August 31, 1994

Prudential
Municipal
Series Fund

(ICON)

Minnesota Series

(LOGO)

<PAGE>
Letter to Shareholders

October 18, 1994

Dear Shareholder:

It has been a most difficult year in the U.S. financial markets.  When we 
last wrote in February interest rates were starting to rise, ending a 
three-year long bull market in bonds.  What started as a trickle has 
become a torrent.  Interest rates have continued to increase this year, 
sending bond prices down sharply.  Of course, as interest rates rise, 
bond prices decline.  In this environment of falling prices and unusual 
volatility, your Prudential Municipal Series Fund -- Minnesota Series 
sought to minimize risk while maximizing your tax-free income.

The Series seeks maximum income exempt from Minnesota and federal 
income taxes* consistent with preservation of capital.  The Series is 
comprised of investment grade municipal obligations with an average 
Aa/AA credit quality as determined by Moody's Investors Service or 
Standard & Poor's Ratings Group.  The Series performed roughly in 
line with the Lipper Minnesota Municipal Debt Average, but because 
long-term interest rates rose, total returns were disappointing.  
As a result, the Series has become more cautious and shortened its 
average maturity.

<TABLE>
                         SERIES PERFORMANCE 
                        As of August 31, 1994
<CAPTION>
                       30-day              Taxable Equivalent Yields  
               NAV    SEC Yield           @28%        @31%       @39.6%
<S>           <C>       <C>               <C>         <C>         <C>
Class A       $11.56     4.1%             6.2%        6.5%        7.4%
Class B       $11.56     3.8%             5.8%        6.1%        6.9% 
Class C       $11.56     N/A              N/A         N/A         N/A
</TABLE>

Investment return and principal value will fluctuate so that an 
investor's shares, when redeemed, may be worth more or less than 
their original cost.  Past performance is no guarantee of future results.

*Interest on municipal obligations may be subject to the federal 
alternative minimum tax. See your Series' prospectus for more details.

N/A = Yield information with respect to Class C is not available 
as operations commenced in August 1994.

                                  -1-

<PAGE>

<TABLE>
                                   TOTAL RETURNS
<CAPTION>
                     Historical (As of 8/31/94)1    Average Annual (As of 9/30/94)2
                     1-Yr.  5-Yr.  Since Incep.**     1-Yr.  5-Yr.  Since Incep.**
<S>                  <C>    <C>       <C>             <C>    <C>       <C>
Class A              -0.9%  N/A        +34.8%         -5.8%  N/A        +5.6%
Class B              -1.3%  +35.5%    +114.7%         -8.2%  +5.9%      +7.8%
Class C               N/A   N/A         -0.4%          N/A   N/A        -2.3%
Lipper MN 
Muni Debt Avg.***    -0.4%  +42.2%    +134.8%          N/A   N/A         N/A
</TABLE>

1 Source: Lipper Analytical Services, Inc. These figures do not take into 
account sales charges.

2 Source: Prudential Mutual Fund Management, Inc.  These averages take 
into account applicable sales charges.  The Series charges a maximum 
initial sales charge of 3% for Class A shares.  Class B shares are 
subject to a declining contingent deferred sales charge of 5%, 4%, 
3%, 2%, 1% and 1%, respectively, for the first six years.  Class B 
shares will automatically convert to Class A shares approximately 
seven years after purchase.  This conversion feature is expected to 
be implemented in February 1995.  Class C shares are subject to a 
contingent deferred sales charge of 1% during the first year. 

**Inception on January 22, 1990 for Class A, and October 4, 1984 for 
Class B and August 1, 1994 for Class C.

***These are the average returns of 29 Minnesota municipal debt funds 
for one-year, five-year, and since inception of Class B shares, as 
determined by Lipper Analytical Services, Inc.

Note:  Without expense subsidies and management fee waivers, the 
Series' historical and average annual total returns would have been 
lower.  The Series' Class B average annual total return since inception 
would have been 7.6%

Once Was Not Enough

When we wrote to you in February, the Federal Reserve raised short-term 
interest rates for the first time in years, hoping to control inflation.  
Since then, the Fed has moved four more times, until the federal funds 
rate (the overnight interbank lending rate) now stands at 4.75%, up from 
3% at the start of the year.  The Fed also increased the discount rate 
(at which it lends banks money) to 4% from 3% over the same period.

Interest rates rise when the financial markets fear inflation, the bond 
holder's enemy. Inflation is feared because it robs purchasing power from 
a bond's fixed-interest rate.

Municipal bond interest rates increased by nearly a percentage point, to 
6.46% on August 25 from 5.52% on December 29, 1993, as measured by the 
Bond Buyer's Revenue Bond Index, a widely used yardstick of interest 
rates in the tax-free market.

Minnesota:  Excellent Credit

Minnesota is the strongest economic performer in the north-central 
region of the country, because of growth in health care, medical 
technology and financial services. The state's 3.6% unemployment 
rate is among the lowest in the country.

                                  -2-

<PAGE>

The state maintains an excellent credit position that continues to 
improve as a result of its favorable economic growth, balanced economy, 
strengthening financial position, and consistent application of 
conservative debt and fiscal policies.  

With a revenue surplus this year and after much debate, state 
government adopted  a variety of tax cuts and spending increases.  
Minnesota's governor vetoed $174 million in further expenses to 
maintain the traditional $350 million surplus.

One unresolved issue is how to fund MinnesotaCare, the state's 
universal health care plan which is scheduled for implementation 
in mid-1997.  Although some want to raise revenue with a new top 
income tax rate, the governor has threatened to veto this move.

With new issues down 51.7% to date this year in Minnesota, bonds 
have been scarce.  We have remained fully invested, anticipating 
this situation will continue through the year.

A Tax Reminder

As a result of the Federal Revenue Reconciliation Act of 1993, 
which affects bonds purchased after April 30, 1993, it is possible 
that this year you may have some taxable income from your tax-free 
municipal bond fund.  The law stipulates that the portion of any 
gain realized on the sale or retirement of a tax-free bond purchased 
at a market discount to its face value must be taxed as ordinary income.  

Following this change in federal tax law, some discount bonds have 
been selling at levels so cheap they will produce a higher after-tax 
return than other bonds not subject to the provisions of the new law.  
We have occasionally taken advantage of this market imbalance because 
we have determined that at very low prices these bonds can still 
provide you with a higher after-tax return on your investment.

The Outlook

We expect volatility in the municipal bond market until the economy 
reaches a level of growth that is sustainable without causing inflation.  
If the economy continues to surge, the ever vigilant Fed will move again, 
boosting short-term rates.  If the economy slows substantially, long 
term rates should stabilize.  Although rates may keep rising, we believe 
that most of the increase is now behind us.

In the months ahead, we expect supply -- or the lack of it -- to become 
more important in the tax-free municipal bond market.  Through the first 
eight months of the year, new issue volume is off 42%, according to Securities

                                    -3-

<PAGE>

Data Co., which tracks this statistic.  The pace is accelerating.  In August, 
new issue volume fell 56%.  

As always, it is a pleasure to have you as a shareholder in the 
Prudential Municipal Series Fund -- Minnesota Series, and to take 
this opportunity to report our activities to you.


Sincerely,

Lawrence C. McQuade                          
President                                    

Christian Smith
Portfolio Manager

                                       -4-

<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                       Portfolio of Investments
MINNESOTA SERIES                                                August 31, 1994
<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                   Value           
(Unaudited)     (000)           Description (a)       (Note 1)       
<C>           <C>           <S>                      <C>
                            LONG-TERM INVESTMENTS--97.8%
                            Braham Indpt. Sch. Dist., No. 314,
AA*            $    425     5.20%, 2/1/13..........  $   386,066
                            Breckenridge Hosp. Facs. Rev.,
                              Franciscan Sisters Healthcare,
NR                  800(D)  9.375%, 9/1/17, Ser.
                              B1...................      918,648
                            Dakota Cnty. Hsg. & Redev. Auth.,
                              Burnsville & Inner Grove,
                              Sngl. Fam. Mtge.,
Aaa                  10     9.375%, 5/1/18,
                              F.G.I.C..............       10,423
                            Metropolitan Council of Minneapolis,
                              Hubert H. Humphrey Metrodome,
A                   500     6.00%, 10/1/09.........      505,240
                            St. Paul Met. Area,
Aaa                 750     6.25%, 12/1/06, Ser.
                              A....................      784,545
Aaa                 500     6.75%, 9/1/10, Ser.
                              D....................      527,135
                            Minneapolis Cmnty. Dev.
                              Agcy.,
                              St. Paul Hsg. &
                              Redev.
                              Auth. Rev.,
Aa                   10     9.875%, 12/1/15........       10,371
                            Tax Increment Rev., M.B.I.A.,
Aaa                 750     Zero Coupon, 9/1/01....      527,543
Aaa               1,000     Zero Coupon, 3/1/06....      534,620
Aaa               1,000     Zero Coupon, 9/1/07....      487,720
                            Minneapolis Hosp. Rev.,
                              Lifespan Inc., Ser.
                              B,
Aaa                 820(D)  8.70%, 12/1/02.........      933,660
A                   800     8.125%, 8/1/17.........      877,952
                            Minneapolis-St. Paul Hsg. & Redev.
                              Auth., Hlth. Care Sys. Rev.,
                            4.75%, 11/15/18, Ser.
Aaa               1,500       A, A.M.B.A.C.........    1,201,200
                            Minneapolis-St. Paul
                              Hsg. Fin. Brd. Rev.,
                              Sngl. Fam. Mtge.,
AAA*              1,000     7.30%, 8/1/31,
                              G.N.M.A..............    1,045,850
                            Minneapolis-St. Paul Met. Arpts.,
Aaa               1,000     7.80%, 1/1/14, Ser.
                              7....................    1,114,790
                            Minnesota Pub. Facs.
                              Auth., Wtr. Poll.
                              Ctrl. Rev.,
AA+*           $    500     6.90%, 3/1/03, Ser.
                              A....................  $   548,245
AA+*                650     7.00%, 3/1/09..........      695,630
                            Minnesota St. Higher
                              Ed. Facs. Auth. Rev.,
                              Macalester Coll.,
AA-*                500     6.40%, 3/1/22..........      511,330
                            St. Marys Coll.,
Baa                 625     6.10%, 10/1/16.........      617,487
                            Univ. of St. Thomas,
A1                  300     5.60%, 9/1/14..........      282,468
                            Northern Mun. Pwr.
                              Agcy., Elec. Sys.
                              Rev.,
A                   370     7.25%, 1/1/16, Ser.
                              A....................      401,221
                            5.50%, 1/1/18, Ser. B,
Aaa                 750       A.M.B.A.C............      698,715
                            Northfield Coll. Fac.
                              Rev.,
                              St. Olaf Coll.,
A                   370     6.30%, 10/1/12.........      377,999
                            Ramsey Cnty., Gen.
                              Oblig.,
Aaa                 500     7.25%, 2/1/04..........      537,825
                            Red. Wing Indpt. Sch.
                              Dist.,
                            No. 256 Sch. Bldg.,
Aa                  500     5.60%, 2/1/09..........      488,385
                            Robbinsdale Hosp. Rev.,
                              North Memorial Med.
                              Ctr.,
Aaa               1,000     5.55%, 5/15/19,
                              A.M.B.A.C............      914,720
                            Rochester Hlth. Care
                              Facs. Rev., Mayo Med.
                              Ctr.,
NR                  500(D)  8.30%, 11/15/07, Ser.
                              A....................      575,985
                            Science Museum,
                            St. Paul, Cert. of
                              Part.,
AAA*              1,280(D)  7.50%, 12/15/01........    1,369,462
                            Southern Mun. Pwr.
                              Agcy., Pwr. Supply
                              Sys. Rev., Ser. B,
Aaa                 500     5.50%, 1/1/15,
                              A.M.B.A.C............      468,580
</TABLE>
 
                                      -5-     See Notes to Financial Statements.

<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                       
MINNESOTA SERIES                                                
<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                  Value
(Unaudited)     (000)          Description (a)        (Note 1)
<C>           <C>           <S>                      <C>
                            St. Louis Park Hosp.
                              Rev., Methodist
                              Hosp., Ser. C,
Aaa            $    500     5.20%, 7/1/16,
                              A.M.B.A.C............  $   438,945
Aaa               1,400(D)/@ 7.25%, 7/1/18,
                              A.M.B.A.C............    1,577,016
                            St. Paul Hsg. & Redev.
                              Auth., Ramsey Med.
                              Ctr. Proj.,
Aaa                 500     5.55%, 5/15/23,
                              A.M.B.A.C............      451,675
                            Tax Increment Rev.,
Aaa               1,000     5.25%, 9/1/05,
                              A.M.B.A.C............      982,790
                            St. Paul Port Auth.,
                              Energy Park Tax
                              Increment Rev.,
AAA*                855(D)  8.00%, 12/1/07.........      955,745
                            Univ. of Minnesota
                              Rev.,
AAA*                150(D)  9.625%, 2/1/05.........      157,168
Aa                1,000     6.00%, 2/1/11, Ser.
                              A....................    1,004,080
                            Verndale Indpt. Sch. Dist., No. 818,
                              Sch. Bldg.
AA*                 955     4.875%, 2/1/14.........      823,859
                            Western Mun. Pwr.
                              Agcy., Supply Rev.,
A1                  500     5.50%, 1/1/15, Ser.
                              A....................      459,270
                                                     -----------
                            Total Investments--97.8%
                            (cost $24,115,494; Note
                              4)...................   25,204,363
                            Other assets in excess
                              of
                              liabilities--2.2%....      571,627
                                                     -----------
                            Net Assets--100%.......  $25,775,990
                                                     -----------
                                                     -----------
</TABLE>
 
- ------------------
(a) The following abbreviations are used in portfolio descriptions:
     A.M.B.A.C.--American Municipal Bond Assurance Corporation.
     F.G.I.C.--Financial Guaranty Insurance Company.
     G.N.M.A.--Government National Mortgage Association.
     M.B.I.A.--Municipal Bond Insurance Association.
 (D) Prerefunded issues are secured by escrowed cash
     and/or direct U.S. guaranteed obligations.
   @ Pledged as initial margin on financial futures
     contracts.
   * Standard & Poor's rating.
 
NR--Not Rated by Moody's or Standard & Poor's.
The Fund's current Statement of Additional Information contains a description of
Moody's and Standard & Poor's ratings.
                                      -6-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 MINNESOTA SERIES
 Statement of Assets and Liabilities
<TABLE>
<CAPTION>
Assets                                                                                      August 31, 1994
                                                                                            ---------------
<S>                                                                                         <C>
Investments, at value (cost $24,115,494).................................................     $25,204,363
Receivable for investments sold..........................................................         516,583
Interest receivable......................................................................         405,302
Other assets.............................................................................             865
Receivable for Series shares sold........................................................             450
                                                                                            ---------------
  Total assets...........................................................................      26,127,563
                                                                                            ---------------
Liabilities
Bank overdraft...........................................................................         207,293
Payable for Series shares reacquired.....................................................          60,521
Accrued expenses.........................................................................          38,534
Dividends payable........................................................................          18,294
Management fee payable...................................................................          11,060
Distribution fee payable.................................................................          10,607
Due to broker-variation margin...........................................................           4,254
Deferred trustees' fees..................................................................           1,010
                                                                                            ---------------
  Total liabilities......................................................................         351,573
                                                                                            ---------------
Net Assets...............................................................................     $25,775,990
                                                                                            ---------------
                                                                                            ---------------
Net assets were comprised of:
  Shares of beneficial interest, at par..................................................     $    22,301
  Paid-in capital in excess of par.......................................................      24,629,740
                                                                                            ---------------
                                                                                               24,652,041
  Accumulated net realized gain on investments...........................................          55,767
  Net unrealized appreciation on investments.............................................       1,068,182
                                                                                            ---------------
  Net assets, August 31, 1994............................................................     $25,775,990
                                                                                            ---------------
                                                                                            ---------------
Class A:
  Net asset value and redemption price per share
    ($1,286,717 / 111,328 shares of beneficial interest issued and outstanding)..........          $11.56
  Maximum sales charge (3.0% of offering price)..........................................             .36
                                                                                            ---------------
  Maximum offering price to public.......................................................          $11.92
                                                                                            ---------------
                                                                                            ---------------
Class B:
  Net asset value, offering price and redemption price per share
    ($24,489,074 / 2,118,742 shares of beneficial interest issued and outstanding).......          $11.56
                                                                                            ---------------
                                                                                            ---------------
Class C:
  Net asset value, offering price and redemption price per share
    ($198.92 / 17.21 shares of beneficial interest issued and outstanding)...............          $11.56
                                                                                            ---------------
                                                                                            ---------------
</TABLE>
 
See Notes to Financial Statements.
                                      -7-

<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 MINNESOTA SERIES
 Statement of Operations
<TABLE>
<CAPTION>
                                         Year Ended
                                         August 31,
Net Investment Income                       1994
                                         -----------
<S>                                      <C>
Income
  Interest............................   $ 1,664,193
                                         -----------
Expenses
  Management fee......................       136,463
  Distribution fee--Class A...........         1,179
  Distribution fee--Class B...........       130,567
  Custodian's fees and expenses.......        62,000
  Transfer agent's fees and
  expenses............................        34,600
  Registration fees...................        27,500
  Reports to shareholders.............        26,000
  Legal fees..........................        15,000
  Audit fee...........................        10,500
  Trustees' fees......................         3,375
  Miscellaneous.......................           643
                                         -----------
    Total expenses....................       447,827
                                         -----------
Net investment income.................     1,216,366
                                         -----------
Realized and Unrealized
Gain (Loss) on Investments
Net realized gain (loss) on:
  Investment transactions.............        98,727
  Financial futures transactions......        95,075
                                         -----------
                                             193,802
                                         -----------
Net change in unrealized appreciation/
  depreciation on:
  Investments.........................    (1,783,295)
  Financial futures contracts.........       (20,250)
                                         -----------
                                          (1,803,545)
                                         -----------
Net gain (loss) on investments........    (1,609,743)
                                         -----------
Net Decrease in Net Assets
Resulting from Operations.............   $  (393,377)
                                         -----------
                                         -----------
</TABLE>
 
 PRUDENTIAL MUNICIPAL SERIES FUND
 MINNESOTA SERIES
 Statement of Changes in Net Assets
<TABLE>
<CAPTION>
                               Year Ended August 31,
Increase (Decrease)          --------------------------
in Net Assets                   1994           1993
                             -----------    -----------
<S>                          <C>            <C>
Operations
  Net investment income....  $ 1,216,366    $ 1,238,313
  Net realized gain on
    investment
    transactions...........      193,802        142,719
  Net change in unrealized
    appreciation on
    investments............   (1,803,545)     1,111,143
                             -----------    -----------
  Net increase (decrease)
    in net
    assets resulting from
    operations.............     (393,377)     2,492,175
                             -----------    -----------
Dividends and distributions (Note 1)
  Dividends from net
    investment income
    Class A................      (57,132)       (31,491)
    Class B................   (1,159,234)    (1,206,822)
                             -----------    -----------
                              (1,216,366)    (1,238,313)
                             -----------    -----------
  Distributions from net
    realized gains
    Class A................       (6,669)          (992)
    Class B................     (189,576)       (46,636)
                             -----------    -----------
                                (196,245)       (47,628)
                             -----------    -----------
Series share transactions
  (Note 5)
  Net proceeds from shares
    sold...................    3,930,513      4,761,162
  Net asset value of shares
    issued in reinvestment
    of dividends and
    distributions..........      949,351        838,823
  Cost of shares
  reacquired...............   (4,757,735)    (4,494,663)
                             -----------    -----------
  Net increase in net
    assets from Series
    share transactions.....      122,129      1,105,322
                             -----------    -----------
Total increase
  (decrease)...............   (1,683,859)     2,311,556
Net Assets
Beginning of year..........   27,459,849     25,148,293
                             -----------    -----------
End of year................  $25,775,990    $27,459,849
                             -----------    -----------
                             -----------    -----------
</TABLE>
 
See Notes to Financial Statements.        See Notes to Financial Statements.
                                      -8-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 MINNESOTA SERIES
 Notes to Financial Statements
   Prudential Municipal Series Fund (the ``Fund'') is registered under the
Investment Company Act of 1940 as an open-end investment company. The Fund was
organized as a Massachusetts business trust on May 18, 1984 and consists of
seventeen series. The monies of each series are invested in separate,
independently managed portfolios. The Minnesota Series (the ``Series'')
commenced investment operations in October, 1984. The Series is diversified and
seeks to achieve its investment objective of obtaining the maximum amount of
income exempt from federal and applicable state income taxes with the minimum of
risk by investing in ``investment grade'' tax-exempt securities whose ratings
are within the four highest ratings categories by a nationally recognized
statistical rating organization or, if not rated, are of comparable quality. The
ability of the issuers of the securities held by the Series to meet their
obligations may be affected by economic developments in a specific state,
industry or region.
                              
Note 1. Accounting            The following is a summary
Policies                      of significant accounting poli-
                              cies followed by the Fund and the Series in the
preparation of its financial statements.
Securities Valuations: The Series values municipal securities (including
commitments to purchase such securities on a ``when-issued'' basis) on the basis
of prices provided by a pricing service which uses information with respect to
transactions in bonds, quotations from bond dealers, market transactions in
comparable securities and various relationships between securities in
determining values. If market quotations are not readily available from such
pricing service, a security is valued at its fair value as determined under
procedures established by the Trustees.
   Short-term securities which mature in more than 60 days are valued at current
market quotations. Short-term securities which mature in 60 days or less are
valued at amortized cost.
   All securities are valued as of 4:15 P.M., New York time.
Financial Futures Contracts: A financial futures contract is an agreement to
purchase (long) or sell (short) an agreed amount of debt securities at a set
price for delivery on a future date. Upon entering into a financial futures
contract, the Series is required to pledge to the broker an amount of cash
and/or other assets equal to a certain percentage of the contract amount. This
amount is known as the ``initial margin''. Subsequent payments, known as
``variation margin'', are made or received by the Series each day, depending on
the daily fluctuations in the value of the underlying security. Such variation
margin is recorded for financial statement purposes on a daily basis as
unrealized gain or loss. The Series invests in financial futures contracts
solely for the purpose of hedging its existing portfolio securities or
securities the Series intends to purchase against fluctuations in value caused
by changes in prevailing market interest rates. Should interest rates move
unexpectedly, the Series may not achieve the anticipated benefits of the
financial futures contracts and may realize a loss. The use of futures
transactions involves the risk of imperfect correlation in movements in the
price of futures contracts, interest rates and the underlying hedged assets.
Securities Transactions and Investment Income: Securities transactions are
recorded on the trade date. Realized gains and losses on sales of securities are
calculated on the identified cost basis. Interest income is recorded on the
accrual basis. The Series amortizes premiums and original issue discount paid on
purchases of portfolio securities as adjustments to interest income.
   Net investment income (other than distribution fees) and unrealized and
realized gains or losses are allocated daily to each class of shares based upon
the relative proportion of net assets of each class at the beginning of the day.
Federal Income Taxes: For federal income tax purposes, each series in the Fund
is treated as a separate taxpaying entity. It is the intent of the Series to
continue to meet the requirements of the Internal Revenue Code applicable to
regulated investment companies and to distribute all of its net income to
shareholders. For this reason and because substantially all of the Series' gross
income consists of tax-exempt interest, no federal income tax provision is
required.
Dividends and Distributions: The Series declares daily dividends from net
investment income. Payment of dividends are made monthly. Distributions of net
capital gains, if any, are made annually.
   Income distributions and capital gain distributions are determined in
accordance with income tax regulations which may differ from generally accepted
accounting principles.
                                      -9-
 <PAGE>
<PAGE>
                              
Note 2. Agreements            The Fund has a management
                              agreement with Prudential Mutual Fund Management,
Inc. (``PMF''). Pursuant to this agreement, PMF has responsibility for all
investment advisory services and supervises the subadviser's performance of such
services. PMF has entered into a subadvisory agreement with The Prudential
Investment Corporation (``PIC''); PIC furnishes investment advisory services in
connection with the management of the Fund. PMF pays for the cost of the
subadviser's services, the compensation of officers and employees of the Fund,
and occupancy and certain clerical and bookkeeping costs of the Fund. The Fund
bears all other costs and expenses.
   The management fee paid PMF is computed daily and payable monthly, at an
annual rate of .50 of 1% of the average daily net assets of the Series.
   The Fund has distribution agreements with Prudential Mutual Fund
Distributors, Inc. (``PMFD''), which acts as the distributor of the Class A
shares of the Fund, and with Prudential Securities Incorporated (``PSI''), which
acts as distributor of the Class B and Class C shares of the Fund (collectively
the ``Distributors''). The Fund compensates the Distributors for distributing
and servicing the Fund's Class A, Class B and Class C shares, pursuant to plans
of distribution, (the ``Class A, B and C Plans'') regardless of expenses
actually incurred by them. The distribution fees are accrued daily and payable
monthly.
   On July 19, 1994, shareholders of the Fund approved amendments to the Class A
and Class B distribution plans under which the distribution plans became
compensation plans, effective August 1, 1994. Prior thereto, the distribution
plans were reimbursement plans, under which PMFD and PSI were reimbursed for
expenses actually incurred by them up to the amount permitted under the Class A
and Class B Plans, respectively. The Fund is not obligated to pay any prior or
future excess distribution costs (costs incurred by the Distributors in excess
of distribution fees paid by the Fund or contingent deferred sales charges
received by the Distributors). The rate of the distribution fees charged to
Class A and Class B shares of the Fund did not change under the amended plans of
distribution. The Fund began offering Class C shares on August 1, 1994.
   Pursuant to the Class A, B and C Plans, the Fund compensates the Distributors
for distribution-related activities at an annual rate of up to .30 of 1%, .50 of
1% and 1%, of the average daily net assets of the Class A, B and C shares,
respectively. Such expenses under the Plans were .10 of 1%, .50 of 1% and .75 of
1% of the average daily net assets of the Class A, B and C shares, respectively,
for the fiscal year ended August 31, 1994.
   PMFD has advised the Series that it has received approximately $20,000 in
front-end sales charges resulting from sales of Class A shares during the fiscal
year ended August 31, 1994. From these fees, PMFD paid such sales charges to PSI
and Pruco Securities Corporation, affiliated broker-dealers, which in turn paid
commissions to salespersons and incurred other distribution costs.
   PSI has advised the Series that for the fiscal year ended August 31, 1994, it
received approximately $41,900 in contingent deferred sales charges imposed upon
certain redemptions by Class B shareholders.
   PMFD is a wholly-owned subsidiary of PMF; PSI, PMF and PIC are indirect,
wholly-owned subsidiaries of The Prudential Insurance Company of America.
                              
Note 3. Other                 Prudential Mutual Fund Ser-
Transactions                  vices, Inc. (``PMFS''), a 
with Affiliates               wholly-owned subsidiary of 
                              PMF, serves as the Fund's transfer agent and
during the year ended August 31, 1994, the Series incurred fees of approximately
$22,000 for the services of PMFS. As of August 31, 1994, approximately $2,000 of
such fees were due to PMFS. Transfer agent fees and expenses in the Statement of
Operations include certain out-of-pocket expenses paid to non-affiliates.
                              
Note 4. Portfolio             Purchases and sales of port-
Securities                    folio securities of the Series, 
                              excluding short-term investments, for the year
ended August 31, 1994, were $5,579,927 and $5,492,077, respectively.
   At August 31, 1994 the Series sold 17 financial futures contracts on the
Municipal Bond Index expiring in September, 1994. The value at disposition of
such contracts was $1,742,531. The value of such contracts on August 31, 1994
was $1,763,218, thereby resulting in an unrealized loss of $20,687.
   The cost basis of investments for federal income tax purposes at August 31,
1994 was substantially the same as the basis for financial reporting purposes
and, accordingly, net unrealized appreciation of investments for federal income
tax purposes was $1,088,869 (gross unrealized appreciation--$1,517,166; gross
unrealized depreciation--$428,297).
                              
Note 5. Capital               The Series currently offers
                              Class A, Class B and Class C shares. Class A
shares are sold with a front-end sales charge of up to 3.0%. Class B shares are
sold with a contingent
                                      -10-
 <PAGE>
<PAGE>
deferred sales charge which declines from 5% to zero depending on the period of
time the shares are held. Class C shares are sold with a contingent deferred
sales charge of 1% during the first year. Class B shares will automatically
convert to Class A shares on a quarterly basis approximately seven years after
purchase commencing in or about February 1995.
   The Fund has authorized an unlimited number of shares of beneficial interest
of each class at $.01 par value per share.
   Transactions in shares of beneficial interest for the fiscal years ended
August 31, 1994 and 1993 were as follows:
<TABLE>
<S>                                 <C>              <C>
Class A                               Shares           Amount
                                    -------------    -----------
Year ended August 31, 1994:
Shares sold......................        57,307      $   690,269
Shares issued in reinvestment of
  dividends and distributions....         4,480           53,440
Shares reacquired................       (23,024)        (272,744)
                                    -------------    -----------
Net increase in shares
  outstanding....................        38,763      $   470,965
                                    -------------    -----------
                                    -------------    -----------
Year ended August 31, 1993:
Shares sold......................        40,044      $   478,217
Shares issued in reinvestment of
  dividends and distributions....         2,253           26,990
Shares reacquired................        (3,877)         (46,769)
                                    -------------    -----------
Net increase in shares
  outstanding....................        38,420      $   458,438
                                    -------------    -----------
                                    -------------    -----------
<CAPTION>
Class B
<S>                                 <C>              <C>
Year ended August 31, 1994:
Shares sold......................       267,959      $ 3,240,044
Shares issued in reinvestment of
  dividends and distributions....        74,796          895,911
Shares reacquired................      (378,895)      (4,484,991)
                                    -------------    -----------
Net decrease in shares
  outstanding....................       (36,140)     $  (349,036)
                                    -------------    -----------
                                    -------------    -----------
Year ended August 31, 1993:
Shares sold......................       359,576      $ 4,282,945
Shares issued in reinvestment of
  dividends and distributions....        68,005          811,833
Shares reacquired................      (373,090)      (4,447,894)
                                    -------------    -----------
Net increase in shares
  outstanding....................        54,491      $   646,884
                                    -------------    -----------
                                    -------------    -----------
<CAPTION>
Class C
<S>                                 <C>              <C>
August 1, 1994* through
  August 31, 1994:
Shares sold......................            17      $       200
                                    -------------    -----------
                                    -------------    -----------
- ---------------
* Commencement of offering of Class C shares.
</TABLE>
                                      -11-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 MINNESOTA SERIES
 Financial Highlights
<TABLE>
<CAPTION>
                              Class A                                                                                   Class C
        ----------------------------------------------------                          Class B                          ----------
                                                January 22,     ---------------------------------------------------    August 1,
                                                  1990(D)                                                              1994(D)(D)
               Year Ended August 31,              Through                      Year Ended August 31,                    Through
        ------------------------------------     August 31,     ---------------------------------------------------    August 31,
         1994      1993      1992      1991         1990         1994       1993       1992       1991       1990         1994
<S>     <C>       <C>       <C>       <C>       <C>             <C>        <C>        <C>        <C>        <C>        <C>
        ------    ------    ------    ------    ------------    -------    -------    -------    -------    -------    ----------
PER
 SHARE
 OPERATING
  PERFORMANCE:
Net
 asset
value,
beginning
  of
  period... $12.33 $11.78   $11.40    $10.98      $  11.14      $ 12.33    $ 11.78    $ 11.41    $ 10.98    $ 11.14      $11.63
            ------ ------   ------    ------    ------------    -------    -------    -------    -------    -------    ----------
Income
  from
  investment
  operations:
Net
investment
 income...     .58    .62      .66       .64           .39          .53        .58        .61        .60        .62         .04
Net
realized
  and
  unrealized
  gain
(loss)
  on
  investment
  trans-
  actions... (.68)    .57      .38       .42          (.16)        (.68)       .57        .37        .43       (.16)       (.07)
            ------ ------   ------    ------    ------------    -------    -------    -------    -------    -------    ----------
 Total
  from
  investment
    opera-
    tions... (.10)   1.19     1.04      1.06           .23         (.15)      1.15        .98       1.03        .46        (.03)
            ------ ------   ------    ------    ------------    -------    -------    -------    -------    -------    ----------
Less
distributions
Dividends
  from
  net
  investment
  income...  (.58)   (.62)    (.66)     (.64)         (.39)        (.53)      (.58)      (.61)      (.60)      (.62)       (.04)
Distributions
  from net
  realized
  gains..    (.09)   (.02)      --        --            --         (.09)      (.02)        --         --         --          --
            ------ ------   ------    ------    ------------    -------    -------    -------    -------    -------    ----------
 Total
 distri-
 butions...  (.67)   (.64)    (.66)     (.64)         (.39)       (.62)       (.60)      (.61)      (.60)      (.62)       (.04)
            ------ ------   ------    ------    ------------    -------    -------    -------    -------    -------    ----------
Net
 asset
value,
  end
  of
  period.. $11.56  $12.33   $11.78    $11.40      $  10.98      $11.56      $12.33    $ 11.78    $ 11.41    $ 10.98      $11.56
            ------ ------   ------    ------    ------------    -------    -------    -------    -------    -------    ----------
            ------ ------   ------    ------    ------------    -------    -------    -------    -------    -------    ----------
TOTAL
RETURN#:... (0.87)% 10.45%    9.38%     9.93%         2.00%       (1.26)%     9.99%      8.83%      9.64%      4.20%       (.38)%
RATIOS/SUPPLEMENTAL
  DATA:
Net
assets,
  end
  of
 period
 (000)... $1,287    $894      $402      $229          $130      $24,489    $26,565    $24,746    $23,600    $24,080      $  199@@
Average
  net
 assets
 (000)... $1,179    $616      $291      $202           $87      $26,113    $25,387    $24,038    $23,997    $23,558      $  200@@
Ratios
  to
  average
  net
 assets:@
  Expenses,
  including
    distribution
    fees...   1.25%   1.29%   1.22%     1.41%         1.46%*       1.65%      1.69%      1.62%      1.81%      1.78%       2.15%*
  Expenses,
  excluding
    distribution
    fees...   1.15%   1.19%   1.11%     1.31%         1.33%*       1.15%      1.19%      1.12%      1.31%      1.28%       1.40%*
  Net
  investment
  income...   4.84%   5.15%   5.69%     5.73%         5.80%*       4.44%      4.75%      5.29%      5.33%      5.49%       3.86%*
Portfolio
turnover...     21%     27%     32%       56%           30%          21%        27%        32%        56%        30%         21%

 
- ---------------
   * Annualized.
 (D) Commencement of offering of Class A shares.
(D)(D) Commencement of offering of Class C shares.
   # Total return does not consider the effects of sales loads. Total return is calculated assuming a purchase
     of shares on the first day and a sale on the last day of each period reported and includes reinvestment
     of dividends and distributions. Total return for periods of less than one full year are not annualized.
   @ Because of the events referred to in (D)(D) and the timing of such, the ratios for the Class C shares are
     not necessarily comparable to that of the Class A or B shares and are not necessarily indicative of
     future ratios.
  @@ Figures are actual and not rounded to nearest thousand.
</TABLE>
 
See Notes to Financial Statements.
                                      -12-
 <PAGE>
<PAGE>
                          INDEPENDENT AUDITORS' REPORT
The Shareholders and Board of Trustees
Prudential Municipal Series Fund, Minnesota Series
   We have audited the accompanying statement of assets and liabilities of
Prudential Municipal Series Fund, Minnesota Series, including the portfolio of
investments, as of August 31, 1994, the related statements of operations for the
year then ended and of changes in net assets for each of the two years in the
period then ended, and the financial highlights for each of the five years in
the period then ended. These financial statements and financial highlights are
the responsibility of the Fund's management. Our responsibility is to express an
opinion on these financial statements and financial highlights based on our
audits.
   We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements and financial
highlights are free of material misstatement. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements. Our procedures included confirmation of the securities owned as of
August 31, 1994 by correspondence with the custodian and brokers; where replies
were not received from brokers, we performed other auditing procedures. An audit
also includes assessing the accounting principles used and significant estimates
made by management, as well as evaluating the overall financial statement
presentation. We believe that our audits provide a reasonable basis for our
opinion.
   In our opinion, such financial statements and financial highlights present
fairly, in all material respects, the financial position of Prudential Municipal
Series Fund, Minnesota Series, as of August 31, 1994, the results of its
operations, the changes in its net assets, and its financial highlights for the
respective stated periods in conformity with generally accepted accounting
principles.
Deloitte & Touche LLP
New York, New York
October 17, 1994
                         FEDERAL INCOME TAX INFORMATION
   We are required by the Internal Revenue Code to advise you within 60 days of
the Series' fiscal year end (August 31, 1994) as to the federal tax status of
dividends and distributions paid by the Series during such fiscal year.
Accordingly, we are advising you that in the fiscal year ended August 31, 1994,
dividends paid from net investment income of $.58 per Class A share, $.53 per
Class B share and $.04 per Class C shares were all federally tax-exempt interest
dividends. In addition, the Series paid to both Class A and B shares a long-term
capital gain distribution of $.037 per share which is taxable as such and a
short-term capital gain distribution of $.050 which is taxable as ordinary
income.
   In January 1995, you will be advised on IRS Form 1099 DIV or substitute 1099
DIV as to the federal tax status of the distributions received by you in
calendar year 1994.
                                      -13-
 <PAGE>
<PAGE>
   These graphs are furnished to you in accordance with SEC regulations. They
compare a $10,000 investment in Prudential Municipal Series Fund: Minnesota
Series (Class A, Class B, and Class C) with a similar investment in the Lehman
Brothers Municipal Bond Index (the Index) by portraying the initial account
values at the commencement of operations of each class and subsequent account
values at the end of each fiscal year (August 31) beginning in 1990 for Class A,
in 1984 for Class B shares and 1994 for Class C shares. For purposes of the
graphs and, unless otherwise indicated, the accompanying tables, it has been
assumed that
(a) the maximum sales charge was deducted from the initial $10,000 investment in
Class A shares; (b) the maximum applicable contingent deferred sales charge was
deducted from the value of the investment in Class B shares and Class C shares,
assuming full redemption on August 31, 1994; (c) all recurring fees (including
management fees) were deducted; and (d) all dividends and distributions were
reinvested. Class B shares will automatically convert to Class A shares on a
quarterly basis approximately seven years after purchase. This conversion
feature is expected to be implemented on or about February 1995 and is not
reflected in the graph. The graph and accompanying tables reflect the past
subsidy and/or waiver of expenses and/or management fees. Without fee waivers
and expense subsidies, the value of a $10,000 investment in the Series and the
Series' average annual total return, as shown above, would have been lower.
   The Index is a weighted index comprised of 21,000 municipal bonds (general
obligation bonds, revenue bonds, insured bonds and prerefunded bonds) selected
by Lehman Brothers as representative of the long-term investment grade municipal
bond market. The Index is an unmanaged index and includes the reinvestment of
all income, but does not reflect the payment of transaction costs and advisory
fees associated with an investment in the Series. The securities which comprise
the Index may differ substantially from the securities in the Series' portfolio
because the Index, among other things, is not state specific. The Lehman
Brothers Municipal Bond Index is not the only index which may be used to
characterize performance of long-term, investment-grade tax-exempt bond funds
and other indexes may portray different comparative performance.
                                      -14-
 <PAGE>
<PAGE>
Trustees
Edward D. Beach
Eugene C. Dorsey
Delayne Dedrick Gold
Harry A. Jacobs, Jr.
Lawrence C. McQuade
Thomas T. Mooney
Thomas H. O'Brien
Nancy H. Teeters

Officers
Lawrence C. McQuade, President
Robert F. Gunia, Vice President
Susan C. Cote, Treasurer
S. Jane Rose, Secretary
Ronald Amblard, Assistant Secretary
Deborah A. Docs, Assistant Secretary

Manager
Prudential Mutual Fund Management, Inc.
One Seaport Plaza
New York, NY 10292

Investment Adviser
The Prudential Investment Corporation
Prudential Plaza
Newark, NJ 07101

Distributors
Prudential Mutual Fund Distributors, Inc.
Prudential Securities Incorporated
One Seaport Plaza
New York, NY 10292

Custodian
State Street Bank and Trust Company
One Heritage Drive
North Quincy, MA 02171

Transfer Agent
Prudential Mutual Fund Services, Inc.
P.O. Box 15005
New Brunswick, NJ 08906

Independent Accountants
Deloitte & Touche LLP
1633 Broadway
New York, NY 10019

Legal Counsel
Gardner, Carton & Douglas
Quaker Tower
321 North Clark Street
Chicago, IL 60610-4795

Prudential Mutual Funds
One Seaport Plaza
New York, NY 10292
Toll free (800) 225-1852
Collect (908) 417-7555

This report is not authorized for distribution to prospective investors 
unless preceded or accompanied by a current prospectus.

74435M697  
74435M713                                 MF 121E
74435M549            (LOGO)         Cat. #642187W


























































ANNUAL REPORT                            August 31, 1994

Prudential
Municipal Series Fund

(ICON)

North Carolina Series

(LOGO)


<PAGE>

Letter to Shareholders

October 18, 1994

Dear Shareholder:

  It has been a most difficult year in the U.S. financial markets. When we last
wrote in February interest rates were starting to rise, ending a three-year 
long bull market in bonds. What started as a trickle has become a torrent. 
Interest rates have continued to increase this year, sending bond prices down 
sharply.  Of course, as interest rates rise, bond prices decline.  In this 
environment of falling prices and unusual volatility, your Prudential Municipal
Series Fund -- North Carolina Series sought to minimize risk while maximizing 
your tax-free income.

  The Series seeks maximum income exempt from North Carolina and federal income
taxes* consistent with preservation of capital.  The Series is comprised of 
investment grade municipal obligations with an average Aa/AA credit quality as 
determined by Moody's Investors Service or Standard & Poor's Ratings Group. The
Series performed in line with the Lipper North Carolina Municipal Debt Average 
over the last year, but because long-term interest rates rose, total returns 
were disappointing. As a result, the Series has become more cautious and 
shortened its average maturity.


                          SERIES PERFORMANCE
                         As of August 31, 1994

<TABLE>
<CAPTION>
                       30-day                  Taxable Equivalent Yields
             NAV     SEC Yield                 @28%    @31%    @39.6%
<S>          <C>      <C>                       <C>     <C>     <C>

Class A    $11.06       4.7%                     7.1%   7.5%      8.5%

Class B    $11.06       4.5%                     6.8%   7.1%       8.1%

Class C    $11.06       N/A                      N/A     N/A       N/A

</TABLE>

  Investment return and principal value will fluctuate so that an investor's 
shares, when redeemed, may be worth more or less than their original cost. Past
performance is no guarantee of future results.
  Interest on municipal obligations may be subject to the federal alternative 
minimum tax. See your Series' prospectus for more details.
  N/A = Yield information with respect to Class C is not available as 
operations commenced in August 1994.

                               -1-

<PAGE>

                           TOTAL RETURNS

<TABLE>
<CAPTION>

             Historical (As of 8/31/94)1       Average Annual (As of 9/30/94)2
            1-Yr.  5-Yr.   Since Incep.**      1-Yr.     5-Yr.  Since Incep.**

<S>        <C>     <C>         <C>             <C>      <C>          <C>
Class A    -1.4%   N/A         +38.6%          -7.4%     N/A         +6.1%

Class B    -1.8%  +39.2%      +103.7%          -9.9%    +6.4%        +7.5%

Class C     N/A     N/A        +0.02%            N/A      N/A         -2.9%

Lipper NC
Muni Debt 
Avg.***    -1.8%  +41.4%       +116.6%            N/A     N/A           N/A
</TABLE>

  1 Source: Lipper Analytical Services, Inc. These figures do not take into 
account sales charges.

  2 Source: Prudential Mutual Fund Management, Inc.  These averages take into 
account applicable sales charges.  The Series charges a maximum initial sales 
charge of 3% for Class A shares.  Class B shares are subject to a declining 
contingent deferred sales charge of 5%, 4%, 3%, 2%, 1% and 1%, respectively, 
for the first six years.  Class B shares will automatically convert to Class A 
shares approximately seven years after purchase.  This conversion feature is 
expected to be implemented in February 1995. Class C shares are subject to a 
contingent deferred sales charge of 1% during the first year.

  **Inception on January 22, 1990 for Class A, and February 13, 1985 for Class 
B and August 1, 1994 for Class C.

  ***These are the average returns of 25 North Carolina municipal debt funds 
for one-year, five-year, and since inception of Class B shares, as determined 
by Lipper Analytical Services, Inc.

  Note:  Without expense subsidies and management fee waivers, the Series' 
historical and average annual total returns would have been lower. The Series'
Class B average annual total return since inception would have been 7.4%.

Once Was Not Enough

  When we wrote to you in February, the Federal Reserve raised short-term 
interest rates for the first time in years, hoping to control inflation. Since 
then, the Fed has moved four more times, until the federal funds rate (the 
overnight interbank lending rate) now stands at 4.75%, up from 3% at the start 
of the year. The Fed also increased the discount rate (at which it lends banks 
money) to 4% from 3% over the same period.

  Interest rates rise when the financial markets fear inflation, the bond 
holder's enemy. Inflation is feared because it robs purchasing power from a 
bond's fixed-interest rate.

  Municipal bond interest rates increased by nearly a percentage point, to 
6.46% on August 25 from 5.52% on December 29, 1993, as measured by the Bond 
Buyer's Revenue Bond Index, a widely used yardstick of interest rates in the 
tax-free market.

North Carolina: A Solid Economy

  North Carolina continues to demonstrate solid economic growth while still 
diversifying its base.  Tobacco and textiles remain important to the state's 
economy (but less so) while the state's financial services sector is rising as 
its high-tech research park, one of the largest in the nation.  North Carolina 
offers low property and labor costs.  Jobs tend to follow.  This is a 
right-to-work state and the unemployment rate is 3.7%.

                                      -2-

<PAGE>

  The state's growing economy and conservative fiscal management have helped 
it maintain an excellent fiscal condition, and its long-term debt is rated 
AAA/Aaa by both major rating services.

  Supply of new bonds in North Carolina has been very light.

A Tax Reminder

  As a result of the Federal Revenue Reconciliation Act of 1993, which affects 
bonds purchased after April 30, 1993, it is possible that this year you may 
have some taxable income from your tax-free municipal bond fund.  The law 
stipulates that the portion of any gain realized on the sale or retirement of a
tax-free bond purchased at a market discount to its face value must be taxed as
ordinary income.

  As a result of this change in federal tax law, some discount bonds have been 
selling at levels so cheap they will produce a higher after-tax return than 
other bonds not subject to the provisions of the new law. We have occasionally
taken advantage of this market imbalance because we have determined that at 
very low prices these bonds can still provide you with a higher after-tax 
return on your investment.

The Outlook

  We expect volatility in the municipal bond market until the economy reaches a
level of growth that is sustainable without causing inflation. If the economy 
continues to surge, the ever vigilant Fed will move once again, boosting 
short-term rates. If the economy slows substantially, long term rates should 
stabilize. Although rates may keep rising, we believe that most of the increase
is now behind us.

  In the months ahead, we expect supply -- or the lack of it -- to become more 
important in the tax-free municipal bond market. Through the first eight months
of the year, new issue volume is off 42%, according to Securities Data Co., 
which tracks this statistic. The pace is accelerating. In August, new issue 
volume fell 56%.

                                    -3-

<PAGE>

  As always, it is a pleasure to have you as a shareholder in the Prudential 
Municipal Series Fund -- North Carolina Series, and to take this opportunity 
to report our activities to you.

Sincerely,


Lawrence C. McQuade
President


Marie Conti
Portfolio Manager
                                    -4-

<PAGE>

PRUDENTIAL MUNICIPAL SERIES FUND           Portfolio of Investments
NORTH CAROLINA SERIES                      August 31, 1994

<TABLE>
<CAPTION>
  Moody's     Principal                                        
   Rating      Amount                                   Value  
(Unaudited)     (000)           Description(a)        (Note 1) 

<S>           <C>          <S>                       <C>
                           LONG-TERM INVESTMENTS--98.7%
                           Buncombe Cnty.,
                             Pub. Impvt. Bonds,
Aa             $  1,000(D) 6.90%, 3/1/09...........  $ 1,096,830
                           Charlotte, Cert. of
                             Part., Conv. Fac.
                             Proj., A.M.B.A.C.,
Aaa               3,000    Zero Coupon, 12/1/09....    1,185,780
                           Charlotte Wtr. & Swr.,
Aaa               1,500    6.20%, 6/1/17...........    1,539,990
Aaa               1,000    5.90%, 2/1/19...........      996,080
                           Cleveland Cnty.,
                             F.G.I.C.,
                           5.10%, 6/1/07, Ser.
Aaa               2,500      1993..................    2,378,150
                           Coastal Regl. Mgmt.
                             Auth., Solid Waste
                             Sys.,
A                 2,000    6.50%, 6/1/08...........    2,025,620
                           Craven No. Carolina,
                             Hlth. Care Facs. Rev.,
                           5.625%, 10/1/17,
Aaa                 750      M.B.I.A...............      699,120
                           Dare Cnty., Util. Sys.
                             Rev.,
Aaa                 500    5.75%, 6/1/14...........      482,785
                           Durham, Cert. of Part.,
                             Morgan St. Garage
                             Proj.,
AAA*                500(D) 8.00%, 7/1/06...........      553,135
                           Durham Cnty., Pub.
                             Impvt.,
Aaa               2,000    4.60%, 5/1/04...........    1,876,260
                           Fayetteville, Cert. of
                             Part.,
                             San. Swr. & Pub.
                             Impvt.,
A1                  250    7.10%, 5/1/07...........      276,660
                           6.875%, 12/1/08,
Aaa               1,750      A.M.B.A.C.............    1,872,132
                           Gastonia, Gen. Oblig.,
                             Wtr. Sys. & St.
                             Impvt.,
                           5.25%, 4/1/09,
Aaa               1,625      F.G.I.C...............    1,525,582
                           Greenville, Utility
                             Rev.,
A1                1,000    6.00%, 9/1/16...........      977,330
                           Guilford Cnty., Pub.
                             Impvt.,
Aa1               1,500    5.40%, 4/1/09...........    1,449,990
                           Martin Cnty. Ind. Facs.
                             & Poll. Ctrl. Fin.
                             Auth. Rev.,
                             Weyerhaueser Co.
                             Proj.,
A2                  550    8.50%, 6/15/99..........      623,508
                           Mecklenberg Cnty., Pub.
                             Impvt.,
Aaa            $  1,000    5.00%, 4/1/08...........  $   936,170
Aaa               1,250(D) 6.25%, 1/1/09...........    1,350,200
                           New Hanover Cnty. Hosp.
                             Rev., Regl. Med. Ctr.
                             Proj.,
                           4.75%, 10/1/23,
Aaa               1,600      A.M.B.A.C.............    1,260,432
                           No. Carolina Eastn. Mun. Pwr. Agcy.,
                             Pwr. Sys. Rev.,
Aaa               1,995    6.50%, 1/1/18, E.T.M....    2,152,026
A                 1,005    6.50%, 1/1/18...........    1,007,281
                           7.625%, 1/1/22, Ser. A,
                             A.M.B.A.C.............    1,104,350
Aaa               1,000(D)
Aaa                 650(D) 6.00%, 1/1/26...........      648,200
A                   400    6.00%, 1/1/26...........      372,328
                           No. Carolina Edl. Facs.
                             Fin.
                             Agcy. Rev.,
                             Davidson Coll. Proj.,
                           8.10%, 12/1/12, Ser.
AAA*              1,000(D)@   A.....................   1,095,330
                           No. Carolina Hsg. Fin.
                             Agcy.,
                             Multi-family Mtge.
                             Rev., F.H.A.,
                           8.875%, 7/1/08, Ser.
Aa                   45      C.....................       47,271
Aa                  245    9.75%, 7/1/20, Ser. A...      252,997
                           Sngl. Fam. Mtge. Rev.,
Aa                  960    7.80%, 3/1/21, Ser. G...    1,037,655
                           No. Carolina Med. Care
                             Comn., Hlth. Care
                             Facs. Rev.,
                             Stanley Mem. Hosp.
                             Proj.,
Baa1                650    7.80%, 10/1/19..........      695,123
                           No. Carolina Med. Care
                             Comn., Hosp. Rev.,
                           Annie Pen Mem. Hosp.
                             Proj.,
Baa               1,000    7.50%, 8/15/21..........    1,046,770
                           Baptist Hosp. Proj.,
Aa                1,000    6.00%, 6/1/22...........      948,260
                           Carolina Medicorp Proj.,
                           7.875%, 5/1/15, Ser.
Aaa                 750(D)   A.....................      823,995
Aa                1,500    6.00%, 5/1/21...........    1,423,560
                           Duke Univ. Hosp. Proj.,
                           8.625%, 6/1/10, Ser.
Aa                  595(D)   85A...................      624,334
</TABLE>
 
                                  -5-     See Notes to Financial Statements.
 <PAGE>
<PAGE>


PRUDENTIAL MUNICIPAL SERIES FUND
NORTH CAROLINA SERIES

<TABLE>
<CAPTION>
  Moody's     Principal                                        
   Rating      Amount                                   Value  
(Unaudited)     (000)           Description(a)        (Note 1) 

<S>           <C>          <S>                       <C>
                           No. Carolina Med. Care
                             Comn.,
                             Hosp. Rev.,
                           Mem. Mission Hosp. Inc.
                             Proj.,
A1             $    800    9.10%, 10/1/08..........  $   849,176
                           Mercy Hosp. Proj.,
                           9.625%, 8/1/15, Ser.
AAA*                670(D)   85....................      715,895
                           Presbyterian Hlth. Svcs.
                             Proj.,
Aa                  500    5.50%, 10/1/20..........      447,310
                           Rex Hosp. Proj.,
A1                1,750    6.25%, 6/1/17...........    1,751,137
                           Scotland Mem. Hosp.,
                           8.625%, 10/1/11, Ser.
Baa               1,000(D)   88....................    1,157,530
                           No. Carolina Mun. Pwr.
                             Agcy., No. 1 Catawba
                             Elec. Rev.,
A                 1,000    5.25%, 1/1/09...........      919,450
                           6.00%, 1/1/10,
Aaa               2,500      M.B.I.A...............    2,519,725
                           8.12%, 1/1/12,
Aaa               2,000(D)(D)   M.B.I.A...............   1,745,000
                           7.625%, 1/1/14,
Aaa                 615(D)   A.M.B.A.C.............      679,175
                           7.625%, 1/1/14,
Aaa                 135      A.M.B.A.C.............      148,515
Aaa                 760(D) 8.50%, 1/1/17, Ser. B...      815,419
Aaa                 920(D) 7.00%, 1/1/18...........      960,710
A                    80    7.00%, 1/1/18...........       82,383
                           Northern Hosp. Dist. Surry Cnty.
                             Hlth. Care Facs. Rev.,
                             No. Carolina Hosp.,
Aaa                 700(D) 9.75%, 10/1/12..........      754,523
Baa               1,500    7.875%, 10/1/21.........    1,599,960
                           Piedmont Triad Arpt.
                             Auth.,
                           5.00%, 7/1/16,
Aaa               1,000      M.B.I.A...............      856,320
                           Puerto Rico Aqueduct &
                             Swr. Auth. Rev.,
                           7.875%, 7/1/17, Ser.
Baa               2,000      A.....................    2,218,600
                           Puerto Rico Comnwlth.,
                           5.50%, 7/1/13,
Aaa               1,750      M.B.I.A...............    1,667,067
                           Gen. Oblig.,
                           8.382%, 7/1/20,
Aaa               1,300(D)(D)   F.S.A.................   1,218,750
                           Pub. Impvt. Ref.,
                           5.40%, 7/1/07,
Aaa               1,250      M.B.I.A...............    1,244,163
                           Puerto Rico Hsg. Fin.
                             Corp., Bank & Fin.
                             Agcy.,
Baa               1,000    5.125%, 12/1/05.........      937,620
                           Puerto Rico Hsg. Fin.
                             Corp.,
                           Sngl. Fam. Mtge. Rev.,
                           7.80%, 10/15/21, Ser. A,
                             G.N.M.A...............  $   161,431
Aaa            $    155
                           7.65%, 10/15/22, Ser.
                             1-B, G.N.M.A..........      766,448
Aaa                 740
                           Puerto Rico Ind. Med. & Environ.
                             Poll. Ctrl. Facs.,
                             Upjohn Co. Proj.,
Aa3                 500    7.50%, 12/1/23..........      553,115
                           Puerto Rico Tel. Auth.
                             Rev., Ser. I,
                             M.B.I.A.,
Aaa               1,000(D)(D) 7.184%, 1/25/07.........     937,500
                           Robeson Cnty.,
Aaa                 500(D) 7.80%, 6/1/09...........      559,965
                           Rutherford Cnty., Cert.
                             of Part., Pub. Facs.
                             Proj.,
                           6.20%, 6/1/18,
Aaa               1,000      F.G.I.C...............    1,004,850
                           Union Cnty. Wtr. & Swr.,
                             Solid Waste Rev.,
A1                  850    6.50%, 4/1/07...........      900,507
                           Univ. of No. Carolina at
                             Chapel Hill, Pkg. Sys.
                             Rev., Ser. B,
A1                  850    6.80%, 6/1/06...........      905,004
A1                  500    6.00%, 6/1/08...........      508,785
                           Virgin Islands Pub. Fin.
                             Auth. Rev., Hwy.
                             Trans. Trust Fund,
BBB*              1,050    7.50%, 10/1/96..........    1,107,204
                           7.25%, 10/1/18, Ser.
NR                  700      A.....................      722,134
                           Virgin Islands Terr.,
                             Hugo Ins. Claims Fund
                             Proj.,
                           7.75%, 10/1/06, Ser.
NR                  460      91....................      502,978
                           Virgin Islands Wtr. & Pwr. Auth.,
                             Wtr. Sys. Rev.,
NR                  600    8.50%, 1/1/10, Ser. A...      659,136
                           Wake Cnty. Hosp. Rev.,
                           5.125%, 10/1/26,
Aaa               1,500      M.B.I.A...............    1,261,980
                           Winston Salem,
                             Sngl. Fam. Mtge. Rev.,
A1                  500    8.00%, 9/1/07...........      523,010
                                                     -----------
                           Total long-term
                             investments
                             (cost $68,975,538)....   70,747,709
                                                     -----------
</TABLE>
 
                                 -6-     See Notes to Financial Statements.
 <PAGE>
<PAGE>

PRUDENTIAL MUNICIPAL SERIES FUND
NORTH CAROLINA SERIES

<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                   Value
(Unaudited)     (000)           Description(a)        (Note 1)

<S>           <C>          <S>                       <C>
                           SHORT-TERM INVESTMENTS--0.4%
                           Puerto Rico Comnwlth.,
                             Gov't. Dev. Bank.
                             F.R.W.D.,
                           2.90%, 9/7/94, Ser. 85
VMIG1              $300      (cost $300,000).......  $   300,000
                                                     -----------
                           Total Investments--99.1%
                           (cost $69,275,538; Note
                             4)....................   71,047,709
                           Other assets in excess
                             of
                             liabilities--0.9%.....      665,998
                                                     -----------
                           Net Assets--100%........  $71,713,707
                                                     -----------
                                                     -----------
</TABLE>
 
- ------------------
(a) The following abbreviations are used in portfolio descriptions:
    A.M.B.A.C.--American Municipal Bond Assurance Corporation.
    E.T.M..--Escrowed to Maturity.
    F.G.I.C.--Financial Guaranty Insurance Association.
    F.H.A.--Federal Housing Administration.
    F.R.W.D.--Floating Rate (Weekly) Demand Note #.
    F.S.A.--Financial Security Assurance.
    G.N.M.A.--Government National Mortgage Association.
    M.B.I.A.--Municipal Bond Insurance Association.

     # For purposes of amortized cost valuation, the
       maturity date of Floating Rate Demand Notes is
       considered to be the later of the next date on
       which the security can be redeemed at par, or
       the next date on which the rate of interest is
       adjusted.
     * Standard & Poor's Rating.
   (D) Prerefunded issues are secured by escrowed cash
       and/or direct U.S. guaranteed obligations.
(D)(D) Inverse floating rate bond. The coupon is
       inversely indexed to a floating interest rate.
       The rate shown is the rate at period end.
     @ Entire principal amount pledged as initial
       margin on financial futures contracts.
NR--Not Rated by Moody's or Standard & Poor's.
The Fund's current Statement of Additional Information contains a description of
Moody's and Standard & Poor's ratings.
                                 -7-     See Notes to Financial Statements.
 <PAGE>
<PAGE>

 PRUDENTIAL MUNICIPAL SERIES FUND
 NORTH CAROLINA SERIES
 Statement of Assets and Liabilities
<TABLE>
<CAPTION>
Assets                                                                                      August 31, 1994
                                                                                            ---------------
<S>                                                                                         <C>
Investments, at value (cost $69,275,538).................................................     $71,047,709
Interest receivable......................................................................       1,212,733
Receivable for investments sold..........................................................         748,743
Receivable for Fund shares sold..........................................................          44,417
Deferred expenses and other assets.......................................................           2,067
                                                                                            ---------------
  Total assets...........................................................................      73,055,669
                                                                                            ---------------
Liabilities
Bank overdraft...........................................................................          68,973
Payable for investments purchased........................................................         979,983
Payable for Fund shares reacquired.......................................................         131,876
Dividends payable........................................................................          59,833
Accrued expenses.........................................................................          38,695
Due to Manager...........................................................................          30,471
Due to Distributors......................................................................          29,715
Due to broker - variation margin.........................................................           1,406
Deferred Trustees' fees..................................................................           1,010
                                                                                            ---------------
  Total liabilities......................................................................       1,341,962
                                                                                            ---------------
Net Assets...............................................................................     $71,713,707
                                                                                            ---------------
                                                                                            ---------------
Net assets were comprised of:
  Shares of beneficial interest, at par..................................................     $    64,837
  Paid-in capital in excess of par.......................................................      70,044,569
                                                                                            ---------------
                                                                                               70,109,406
  Accumulated net realized loss on investments...........................................        (177,870)
  Net unrealized appreciation on investments.............................................       1,782,171
                                                                                            ---------------
  Net assets, August 31, 1994............................................................     $71,713,707
                                                                                            ---------------
                                                                                            ---------------
Class A:
  Net asset value and redemption price per share ($2,255,872 / 204,020 shares of
    beneficial interest issued and outstanding)..........................................          $11.06
  Maximum sales charge (3% of offering price)............................................             .34
                                                                                            ---------------
  Maximum offering price to public.......................................................          $11.40
                                                                                            ---------------
Class B:
  Net asset value, offering price and redemption price per share ($69,447,600 / 6,278,792
    shares of
    beneficial interest issued and outstanding)..........................................          $11.06
                                                                                            ---------------
                                                                                            ---------------
Class C:
  Net asset value, offering price and redemption price per share ($10,235 / 925 shares of
    beneficial interest issued and outstanding)..........................................          $11.06
                                                                                            ---------------
                                                                                            ---------------
</TABLE>
 
See Notes to Financial Statements.
                                      -8-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 NORTH CAROLINA SERIES
 Statement of Operations
<TABLE>
<CAPTION>
                                         Year Ended
                                         August 31,
Net Investment Income                       1994
                                         -----------
<S>                                      <C>
Income
  Interest.............................  $ 4,670,468
                                         -----------
Expenses
  Management fee.......................      378,373
  Distribution fee--Class A............        2,067
  Distribution fee--Class B............      368,035
  Custodian's fees and expenses........       84,000
  Transfer agent's fees and expenses...       40,000
  Reports to shareholders..............       29,000
  Registration fees....................       23,000
  Legal fees...........................       15,000
  Audit fee............................       10,500
  Trustees' fees.......................        3,375
  Miscellaneous........................        5,822
                                         -----------
  Total expenses.......................      959,172
                                         -----------
Net investment income..................    3,711,296
                                         -----------
Realized and Unrealized
Gain (Loss) on Investments
Net realized gain on:
  Investment transactions..............      269,989
  Financial futures contract
  transactions.........................        6,075
                                         -----------
                                             276,064
                                         -----------
Net change in unrealized
  appreciation/depreciation on:
  Investments..........................   (5,446,522)
  Financial futures contracts..........       10,000
                                         -----------
                                          (5,436,522)
                                         -----------
Net loss on investments................   (5,160,458)
                                         -----------
Net Decrease in Net Assets
Resulting from Operations..............  $(1,449,162)
                                         -----------
                                         -----------
</TABLE>
 
 PRUDENTIAL MUNICIPAL SERIES FUND
 NORTH CAROLINA SERIES
 Statement of Changes in Net Assets
<TABLE>
<CAPTION>
                                Year Ended August 31,
Increase (Decrease) in       ---------------------------
Net Assets                       1994           1993
                             ------------    -----------
<S>                          <C>             <C>
Operations
  Net investment income....  $  3,711,296    $ 3,592,693
  Net realized gain on
    investment
    transactions...........       276,064      1,658,002
  Net change in unrealized
  appreciation/depreciation
    of investments.........    (5,436,522)     2,485,116
                             ------------    -----------
  Net increase (decrease)
    in net assets resulting
    from operations........    (1,449,162)     7,735,811
                             ------------    -----------
Dividends and distributions
  (Note 1):
  Dividends from net
    investment income
    Class A................      (109,844)       (73,032)
    Class B................    (3,601,431)    (3,519,661)
    Class C................           (21)            --
                             ------------    -----------
                               (3,711,296)    (3,592,693)
                             ------------    -----------
  Distributions from net
    realized gains
    Class A................       (33,123)            --
    Class B................    (1,379,190)            --
                             ------------    -----------
                               (1,412,313)            --
                             ------------    -----------
Series share transactions
  (Note 5)
  Net proceeds from shares
    sold...................     9,251,532     15,956,884
  Net asset value of shares
    issued in reinvestment
    of dividends and
    distributions..........     2,641,848      1,678,716
  Cost of shares
  reacquired...............   (10,898,454)    (8,977,505)
                             ------------    -----------
  Net increase in net
    assets from Series
    share transactions.....       994,926      8,658,095
                             ------------    -----------
Total increase
  (decrease)...............    (5,577,845)    12,801,213
Net Assets
Beginning of year..........    77,291,552     64,490,339
                             ------------    -----------
End of year................  $ 71,713,707    $77,291,552
                             ------------    -----------
                             ------------    -----------
</TABLE>
 
See Notes to Financial Statements.        See Notes to Financial Statements.
                                      -9-
 <PAGE>
<PAGE>

 PRUDENTIAL MUNICIPAL SERIES FUND
 NORTH CAROLINA SERIES
 Notes to Financial Statements
   Prudential Municipal Series Fund (the ``Fund'') is registered under the
Investment Company Act of 1940, as an open-end investment company. The Fund was
organized as a Massachusetts business trust on May 18, 1984 and consists of
seventeen series. The monies of each series are invested in separate,
independently managed portfolios. The North Carolina Series (the ``Series'')
commenced investment operations in February, 1985. The Series is diversified and
seeks to achieve its investment objective of obtaining the maximum amount of
income exempt from federal and applicable state income taxes with the minimum of
risk by investing in ``investment grade'' tax-exempt securities whose ratings
are within the four highest ratings categories by a nationally recognized
statistical rating organization or, if not rated, are of comparable quality. The
ability of the issuers of the securities held by the Series to meet their
obligations may be affected by economic or political developments in a specific
state, industry or region.
                              
Note 1. Accounting            The following is a summary
Policies                      of significant accounting poli-
                              cies followed by the Fund, and the Series, in the
preparation of its financial statements.
Securities Valuations: The Fund values municipal securities (including
commitments to purchase such securities on a ``when-issued'' basis) on the basis
of prices provided by a pricing service which uses information with respect to
transactions in bonds, quotations from bond dealers, market transactions in
comparable securities and various relationships between securities in
determining values. If market quotations are not readily available from such
pricing service, a security is valued at its fair value as determined under
procedures established by the Trustees.
   Short-term securities which mature in more than 60 days are valued at current
market quotations. Short-term securities which mature in 60 days or less are
valued at amortized cost which approximates market value.
   All securities are valued as of 4:15 P.M., New York time.
Financial Futures Contracts: A financial futures contract is an agreement to
purchase (long) or sell (short) an agreed amount of debt securities at a set
price for delivery on a future date. Upon entering into a financial futures
contract, the Series is required to pledge to the broker an amount of cash
and/or other assets equal to a certain percentage of the contract amount. This
amount is known as the ``initial margin''. Subsequent payments, known as
``variation margin'', are made or received by the Series each day, depending on
the daily fluctuations in the value of the underlying security. Such variation
margin is recorded for financial statement purposes on a daily basis as
unrealized gain or loss until the contracts expire or are closed, at which time
the gain or loss is reclassified to realized gain or loss. The Series invests in
financial futures contracts solely for the purpose of hedging its existing
portfolio securities, or securities the Series intends to purchase against
fluctuations in value caused by changes in prevailing market conditions. Should
market conditions move unexpectedly, the Series may not achieve the anticipated
benefits of the financial futures contracts and may realize a loss. The use of
futures transactions involves the risk of imperfect correlation in movements in
the price of futures contracts, interest rates and the underlying hedged assets.
Securities Transactions and Investment Income: Securities transactions are
recorded on the trade date. Realized gains and losses on sales of securities are
calculated on the identified cost basis. Interest income is recorded on the
accrual basis. The Series amortizes premiums and original issue discount paid on
purchases of portfolio securities as adjustments to interest income.
   Net investment income (other than distribution fees) and unrealized and
realized gains or losses are allocated daily to each class of shares based upon
the relative proportion of net assets of each class at the beginning of the day.
Federal Income Taxes: For federal income tax purposes, each series in the Fund
is treated as a separate taxpaying entity. It is the intent of the Series to
continue to meet the requirements of the Internal Revenue Code applicable to
regulated investment companies and to distribute all of its net income to
shareholders. For this reason and because substantially all of the Series' gross
income consists of tax-exempt interest, no federal income tax provision is
required.
Dividends and Distributions: The Series declares daily dividends from net
investment income. Payment of dividends is made monthly. Distributions of net
capital gains, if any, are made annually.
   Income distributions and capital gain distributions are determined in
accordance with income tax regulations which may differ from generally accepted
accounting principles. These differences are primarily due to differing
treatments for short-term capital gains and market discount.
                                      -10-
 <PAGE>
<PAGE>
Reclassification of Capital Accounts: Effective September 1, 1992, the Fund
began accounting and reporting for distributions to shareholders in accordance
with Statement of Position 93-2: Determination, Disclosure, and Financial
Statement Presentation of Income, Capital Gain, and Return of Capital
Distributions by Investment Companies. The effect caused by adopting this
statement was to decrease paid-in capital and increase accumulated net realized
gain on investments by $6,943 compared to amounts previously reported through
August 31, 1993. Net investment income, net realized gains and net assets were
not affected by this change.
                              
Note 2. Agreements            The Fund has a management
                              agreement with Prudential Mutual Fund Management,
Inc. (``PMF''). Pursuant to this agreement, PMF has responsibility for all
investment advisory services and supervises the subadviser's performance of such
services. PMF has entered into a subadvisory agreement with The Prudential
Investment Corporation (``PIC''); PIC furnishes investment advisory services in
connection with the management of the Fund. PMF pays for the services of PIC,
the cost of compensation of officers of the Fund, occupancy and certain clerical
and bookkeeping costs of the Fund. The Fund bears all other costs and expenses.
   The management fee paid PMF is computed daily and payable monthly, at an
annual rate of .50 of 1% of the average daily net assets of the Series.
   The Fund has distribution agreements with Prudential Mutual Fund
Distributors, Inc. (``PMFD''), which acts as the distributor of the Class A
shares of the Fund, and with Prudential Securities Incorporated (``PSI''), which
acts as distributor of the Class B and Class C shares of the Fund (collectively
the ``Distributors''). The Fund compensates the Distributors for distributing
and servicing the Fund's Class A, Class B and Class C shares, pursuant to plans
of distribution, (the ``Class A, B and C Plans'') regardless of expenses
actually incurred by them. The distribution fees are accrued daily and payable
monthly.
   On July 19, 1994, shareholders of the Fund approved amendments to the Class A
and Class B distribution plans under which the distribution plans became
compensation plans, effective August 1, 1994. Prior thereto, the distribution
plans were reimbursement plans, under which PMFD and PSI were reimbursed for
expenses actually incurred by them up to the amount permitted under the Class A
and Class B Plans, respectively. The Fund is not obligated to pay any prior or
future excess distribution costs (costs incurred by the Distributors in excess
of distribution fees paid by the Fund or contingent deferred sales charges
received by the Distributors). The rate of the distribution fees charged to
Class A and Class B shares of the Fund did not change under the amended plans of
distribution. The Fund began offering Class C shares on August 1, 1994.
   Pursuant to the Class A, B and C Plans, the Fund compensates the Distributors
for distribution-related activities at an annual rate of up to .30 of 1%, .50 of
1% and 1%, of the average daily net assets of the Class A, B and C shares,
respectively. Such expenses under the Plans were .10 of 1%, .50 of 1% and .75 of
1% of the average daily net assets of the Class A, B and C shares, respectively,
for the fiscal year ended August 31, 1994.
   PMFD has advised the Series that it has received approximately $26,500 in
front-end sales charges resulting from sales of Class A shares during the fiscal
year ended August 31, 1994. From these fees, PMFD paid such sales charges to PSI
and Pruco Securities Corporation, affiliated broker-dealers, which in turn paid
commissions to salespersons and incurred other distribution costs.
   PSI has advised the Series that for the fiscal year ended August 31, 1994, it
received approximately $64,600 in contingent deferred sales charges imposed upon
certain redemptions by Class B shareholders.
   PMFD is a wholly-owned subsidiary of PMF; PSI, PMF and PIC are indirect,
wholly-owned subsidiaries of The Prudential Insurance Company of America.
                              
Note 3. Other                 Prudential Mutual Fund Ser-
Transactions                  vices, Inc. (``PMFS''), a 
with Affiliates               wholly-owned subsidiary of 
                              PMF, serves as the Fund's transfer agent and
during the year ended August 31, 1994, the Series incurred fees of approximately
$28,900 for the services of PMFS. As of August 31, 1994, approximately $2,400 of
such fees were due to PMFS. Transfer agent fees and expenses in the Statement of
Operations include certain out-of-pocket expenses paid to non-affiliates.
                              
Note 4. Portfolio             Purchases and sales of port-
Securities                    folio securities of the Series, 
                              excluding short-term investments, for the year
ended August 31, 1994 were $14,116,995 and $12,203,398, respectively.
   The cost basis of investments for federal income tax purposes was
substantially the same as for financial reporting purposes and, accordingly, as
of August 31, 1994 net unrealized appreciation of investments, including
short-term investments, for federal income tax purposes is $1,772,171 (gross
unrealized appreciation--$3,180,286; gross unrealized depreciation--$1,408,115).
                                      -11-
 <PAGE>
<PAGE>

   At August 31, 1994, the Series sold 50 financial futures contracts on the
Municipal Bond Index expiring in September 1994. The value at disposition of
such contracts is $467,500. The value of such contracts on August 31, 1994 was
$457,500, thereby resulting in an unrealized gain of $10,000.
   The Fund will elect to treat net capital losses of approximately $107,146
incurred in the ten month period ended August 31, 1994 as having been incurred
in the following fiscal year.
                              
Note 5. Capital               The Series currently offers
                              Class A, Class B and Class C shares. Class A
shares are sold with a front-end sales charge of up to 3.0%. Class B shares are
sold with a contingent deferred sales charge which declines from 5% to zero
depending on the period of time the shares are held. Class C shares are sold
with a contingent deferred sales charge of 1% during the first year. Class B
shares will automatically convert to Class A shares on a quarterly basis
approximately seven years after purchase commencing in or about February 1995.
   The Fund has authorized an unlimited number of shares of beneficial interest
of each class at $.01 par value per share.
   Transactions in shares of beneficial interest for the fiscal years ended
August 31, 1994 and 1993 were as follows:

<TABLE>
<CAPTION>

Class A                             Shares        Amount
                                   ---------    -----------
<S>                                <C>          <C>
Year ended August 31, 1994:
Shares sold......................     81,115    $   947,875
Shares issued in reinvestment of
  dividends and distributions....      8,558         98,262
Shares reacquired................    (33,172)      (382,692)
                                   ---------    -----------
Net increase in shares
  outstanding....................     56,501    $   663,445
                                   ---------    -----------
                                   ---------    -----------
Year ended August 31, 1993:
Shares sold......................     84,457    $   975,980
Shares issued in reinvestment of
  dividends......................      4,050         47,104
Shares reacquired................    (21,713)      (250,645)
                                   ---------    -----------
Net increase in shares
  outstanding....................     66,794    $   772,439
                                   ---------    -----------
                                   ---------    -----------
<CAPTION>
Class B                             Shares        Amount
                                   ---------    -----------
<S>                                <C>          <C>
Year ended August 31, 1994:
Shares sold......................    711,751    $ 8,293,464
Shares issued in reinvestment of
  dividends and distributions....    220,668      2,543,573
Shares reacquired................   (920,864)   (10,515,762)
                                   ---------    -----------
Net increase in shares
  outstanding....................     11,555    $   321,275
                                   ---------    -----------
                                   ---------    -----------
Year ended August 31, 1993:
Shares sold......................  1,288,829    $14,980,904
Shares issued in reinvestment of
  dividends......................    140,597      1,631,612
Shares reacquired................   (753,654)    (8,726,860)
                                   ---------    -----------
Net increase in shares
  outstanding....................    675,772    $ 7,885,656
                                   ---------    -----------
                                   ---------    -----------


<CAPTION>

Class C
<S>                                <C>          <C>
August 1, 1994* through
  August 31, 1994:
Shares sold......................        924    $    10,193
Shares issued in reinvestment of
  dividends......................          1             13
                                   ---------    -----------
Net increase in shares
  outstanding....................        925    $    10,206
                                   ---------    -----------
                                   ---------    -----------
</TABLE>
 
- ------------------
* Commencement of offering of Class C shares.
                                      -12-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 NORTH CAROLINA SERIES
 Financial Highlights

<TABLE>
<CAPTION>
                                                          Class A                                          Class B 
                                ------------------------------------------------------------    -----------------------------
                                                                                January 22,     
                                                                                  1990(D)
                                           Year Ended August 31,                  through           Year Ended August 31,
                                --------------------------------------------     August 31,     -----------------------------
                                 1994      1993          1992          1991         1990         1994       1993       1992
                                ------    ------        -------        ------    ------------    -------    -------    -------
<S>                             <C>       <C>           <C>           <C>       <C>             <C>        <C>        <C>
PER SHARE OPERATING
  PERFORMANCE:
Net asset value, beginning of
  period......................  $12.04    $11.37        $10.86        $10.45       $10.63       $ 12.05    $ 11.37    $ 10.86
                                ------    ------        ------        ------       ------       -------    -------    -------
Income from investment
  operations
Net investment income.........     .61       .65           .67           .67          .41           .56        .60        .62
Net realized and unrealized
  gain (loss) on investment
  transactions................    (.76)      .67           .51           .41         (.18)         (.77)       .68        .51
                                ------    ------       -------        ------       ------       -------    -------    -------
  Total from investment
    operations................    (.15)     1.32          1.18          1.08          .23          (.21)      1.28       1.13
                                ------    ------       -------         ------      ------       -------    -------    -------
Less distributions
Dividends from net investment
  income......................    (.61)     (.65)         (.67)         (.67)        (.41)         (.56)      (.60)      (.62)
Distributions from net
  realized gains..............    (.22)       --            --            --           --          (.22)        --         --
                                ------    ------        ------        ------       -------      -------    -------    -------
  Total distributions.........    (.83)     (.65)         (.67)         (.67)        (.41)         (.78)      (.60)      (.62)
                                ------    ------        ------        ------       -------      -------    -------    -------
Net asset value, end of
  period......................  $11.06    $12.04        $11.37        $10.86       $10.45       $ 11.06    $ 12.05    $ 11.37
                                ------    ------        ------        ------       ------       -------    -------    -------
                                ------    ------        ------        ------       ------       -------    -------    -------
TOTAL RETURN#.................   (1.35)%   11.99%        11.12%        10.63%        2.09%        (1.82)%    11.62%     10.64%
RATIOS/SUPPLEMENTAL DATA:
Net assets, end of period
  (000).......................  $2,256    $1,777        $  917        $  362       $   58       $69,448    $75,515    $63,573
Average net assets (000)......  $2,067    $1,316        $  612        $  246       $   32       $73,606    $67,997    $60,751
Ratios to average net
  assets:##
  Expenses, including
    distribution fees.........     .88%      .87%          .91%          .99%        1.00%*        1.28%      1.27%      1.31%
  Expenses, excluding
    distribution fees.........     .78%      .77%          .81%          .89%         .90%*         .78%       .77%       .81%
  Net investment income.......    5.31%     5.55%         5.90%         6.24%        6.24%*        4.89%      5.18%      5.58%
Portfolio turnover............      17%       38%           36%           27%          24%           17%        38%        36%

<CAPTION>
                                                       Class C
                                                      ----------
                                                      August 1,
                                                      1994(D)(D)
                                                       through
                                                      August 31,
                                 1991       1990         1994
                                -------    -------    ----------
<S>                              <C>       <C>        <C>
PER SHARE OPERATING
  PERFORMANCE:
Net asset value, beginning of
  period......................  $ 10.45    $ 10.65      $11.09
 
                                -------    -------    ----------
Income from investment
  operations
Net investment income.........      .63        .64         .04
Net realized and unrealized
  gain (loss) on investment
  transactions................      .41       (.20)       (.03)
 
                                -------    -------    ----------
  Total from investment
    operations................     1.04        .44         .01
 
                                -------    -------    ----------
Less distributions
Dividends from net investment
  income......................     (.63)      (.64)       (.04)
Distributions from net
  realized gains..............       --         --          --
 
                                -------    -------    ----------
  Total distributions.........     (.63)      (.64)       (.04)
 
                                -------    -------    ----------
Net asset value, end of
  period......................  $ 10.86    $ 10.45      $11.06
 
                                -------    -------    ----------
                                -------    -------    ----------
TOTAL RETURN#.................    10.17%      4.28%        .02%
RATIOS/SUPPLEMENTAL DATA:
Net assets, end of period
  (000).......................  $59,875    $57,429      $   10
Average net assets (000)......  $59,071    $56,745      $    5
Ratios to average net
  assets:##
  Expenses, including
    distribution fees.........     1.39%      1.38%       1.67%*
  Expenses, excluding
    distribution fees.........      .89%       .89%        .92%*
  Net investment income.......     5.88%      5.96%       5.06%*
Portfolio turnover............       27%        24%         17%

 
- ---------------
     * Annualized.
   (D) Commencement of offering of Class A shares.
(D)(D) Commencement of offering of Class C shares.
     # Total return does not consider the effects of sales loads. Total return is calculated assuming a
       purchase of shares on the first day and a sale on the last day of each period reported and includes
       reinvestment of dividends and distributions. Total returns for periods of less than a full year are not
       annualized.
    ## Because of the events referred to in (D)(D) and the timing of such, the ratios for the Class C shares
       are not necessarily comparable to that of Class A or B shares and are not necessarily indicative of
       future ratios.

</TABLE> 
See Notes to Financial Statements.
                                      -13-
 <PAGE>
<PAGE>

                          INDEPENDENT AUDITORS' REPORT

The Shareholders and Board of Trustees
Prudential Municipal Series Fund, North Carolina Series

   We have audited the accompanying statement of assets and liabilities of
Prudential Municipal Series Fund, North Carolina Series, including the portfolio
of investments, as of August 31, 1994, the related statements of operations for
the year then ended and of changes in net assets for each of the two years in
the period then ended, and the financial highlights for each of the five years
in the period then ended. These financial statements and financial highlights
are the responsibility of the Fund's management. Our responsibility is to
express an opinion on these financial statements and financial highlights based
on our audits.
   We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements and financial
highlights are free of material misstatement. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements. Our procedures included confirmation of the securities owned as of
August 31, 1994 by correspondence with the custodian and brokers; where replies
were not received from brokers, we performed other auditing procedures. An audit
also includes assessing the accounting principles used and significant estimates
made by management, as well as evaluating the overall financial statement
presentation. We believe that our audits provide a reasonable basis for our
opinion.
   In our opinion, such financial statements and financial highlights present
fairly, in all material respects, the financial position of Prudential Municipal
Series Fund, North Carolina Series, as of August 31, 1994, the results of its
operations, the changes in its net assets, and its financial highlights for the
respective stated periods in conformity with generally accepted accounting
principles.

Deloitte & Touche LLP
New York, New York
October 17, 1994

                         FEDERAL INCOME TAX INFORMATION

   We are required by the Internal Revenue Code to advise you within 60 days of
the Series' fiscal year end (August 31, 1994) as to the federal tax status of
dividends paid by the Series during such fiscal year. Accordingly, we are
advising you that in the fiscal year ended August 31, 1994, dividends paid from
net investment income of $0.61 per Class A share, $0.56 per Class B share, and
$0.04 per Class C share were all federally tax-exempt interest dividends. In
addition, the Series paid to both Class A and B shares a long-term capital gain
distribution of $.199 per share which is taxable as such and a short-term
capital gain distribution of $.018 which is taxable as ordinary income.
   In January 1995, you will be advised on IRS Form 1099 DIV or Substitute 1099
DIV as to the federal tax status of the distributions received by you in
calendar year 1994.
                                      -14-
 <PAGE>
<PAGE>

   These graphs are furnished to you in accordance with SEC regulations. They
compare a $10,000 investment in Prudential Municipal Series Fund: North Carolina
Series (Class A, Class B, and Class C) with a similar investment in the Lehman
Brothers Municipal Bond Index (the Index) by portraying the initial account
values at the commencement of operations of each class and subsequent account
values at the end of each fiscal year (August 31) beginning in 1990 for Class A
shares and in 1985 for Class B shares and 1994 for Class C shares. For purposes
of the graphs and, unless otherwise indicated, the accompanying tables, it has
been assumed that (a) the maximum sales charge was deducted from the initial
$10,000 investment in Class A shares; (b) the maximum applicable contingent
deferred sales charge was deducted from the value of the investment in Class B
shares and Class C shares assuming full redemption on August 31, 1994; (c) all
recurring fees (including management fees) were deducted; and (d) all dividends
and distributions were reinvested. Class B shares will automatically convert to
Class A shares on a quarterly basis approximately seven years after purchase.
This conversion feature is expected to be implemented on or about February 1995
and is not reflected in the graph. The graph and accompanying tables reflect the
past subsidy and/or waiver of expenses and/or management fees. Without fee
waivers and expense subsidies, the value of a $10,000 investment in the Series
and the Series' average annual total return, as shown above, would have been
lower.
   The Index is a weighted index comprised of 21,000 municipal bonds (general
obligation bonds, revenue bonds, insured bonds and prerefunded bonds) selected
by Lehman Brothers as representative of the long-term investment grade municipal
bond market. The Index is an unmanaged index and includes the reinvestment of
all income, but does not reflect the payment of transaction costs and advisory
fees associated with an investment in the Series. The securities which comprise
the Index may differ substantially from the securities in the Series' portfolio
because the Index, among other things, is not state specific. The Lehman
Brothers Municipal Bond Index is not the only index which may be used to
characterize performance of long-term, investment-grade tax-exempt bond funds
and other indexes may portray different comparative performance.
                                      -15-

<PAGE>


Trustees

Edward D. Beach
Eugene C. Dorsey
Delayne Dedrick Gold
Harry A. Jacobs, Jr.
Lawrence C. McQuade
Thomas T. Mooney
Thomas H. O'Brien
Richard A. Redeker
Nancy H. Teeters

Officers

Lawrence C. McQuade, President
Robert F. Gunia, Vice President
Susan C. Cote, Treasurer
S. Jane Rose, Secretary
Ronald Amblard, Assistant Secretary
Deborah A. Docs, Assistant Secretary

Manager

Prudential Mutual Fund Management, Inc.
One Seaport Plaza
New York, NY 10292

Investment Adviser

The Prudential Investment Corporation
Prudential Plaza
Newark, NJ 07101

Distributors

Prudential Mutual Fund Distributors, Inc.
Prudential Securities Incorporated
One Seaport Plaza
New York, NY 10292

Custodian

State Street Bank and Trust Company
One Heritage Drive
North Quincy, MA 02171

Transfer Agent

Prudential Mutual Fund Services, Inc.
P.O. Box 15005
New Brunswick, NJ 08906

Independent Accountants

Deloitte & Touche LLP
1633 Broadway
New York, NY 10019

Legal Counsel

Gardner, Carton & Douglas
Quaker Tower
321 North Clark Street
Chicago, IL 60610-4795

Prudential Mutual Funds
One Seaport Plaza
New York, NY 10292
Toll free (800) 225-1852, Collect (908) 417-7555

This report is not authorized for distribution to prospective investors 
unless preceded or accompanied by a current prospectus.

74435M812
74435M820                       MF 126E
74435M515         (LOGO)  Cat. #642962S











<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                   Portfolio of Investments
NEW JERSEY SERIES                                           August 31, 1994
<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                  Value            
(Unaudited)     (000)          Description(a)         (Note 1)       
<C>           <C>          <S>                      <C>
                           LONG-TERM INVESTMENTS--97.8%
                           Atlantic City Mun.
                             Utils. Auth. Rev.,
                             Wtr. System,
A-*              $2,000(D) 7.75%, 5/1/17..........    $2,296,380
                           Atlantic City, Gen.
                             Oblig., Ser. A,
Baa1              1,490    Zero Coupon, 11/1/06...       756,443
                           Bergen Cnty., Utils.
                             Auth., Wtr. Poll.
                             Ctrl. Rev., F.G.I.C.,
Aaa               1,000    5.75%, 12/15/05, Ser.
                             B....................     1,030,910
Aaa               7,250    Zero Coupon, 12/15/08,
                           Ser. B.................     3,229,585
Aaa               1,000    5.50%, 12/15/15, Ser.
                             A....................       936,800
                           Camden Cnty. Fin.
                             Auth.,
Aaa               1,600    Zero Coupon, 2/15/03,
                           F.S.A..................     1,025,520
                           Camden Cnty. Mun.
                             Utils. Auth., Sewage
                             Rev.,
Aaa               1,750    8.25%, 12/1/17,
                             F.G.I.C..............     1,958,320
                           Camden Cnty. Poll.
                             Ctrl. Fin. Auth.,
                             Solid Waste Res.
                             Recovery Rev.,
Baa1              2,000    6.70%, 12/1/99, Ser.
                             D....................     2,026,100
Baa1              3,400    7.50%, 12/1/09, Ser.
                             B....................     3,424,140
                           Cape May Cnty. Ind.
                             Poll. Ctrl., Fin.
                             Auth. Rev.,
Aaa               2,615    6.80%, 3/1/21,
                             M.B.I.A..............     2,909,554
                           Cherry Hill Township,
Aa                1,000    5.90%, 6/1/05..........     1,076,690
Aa                2,000    6.30%, 6/1/12..........     2,125,480
                           Cinnaminson Sewage
                             Auth. Rev.,
A1                1,600    7.40%, 2/1/15..........     1,803,008
                           Delaware River Jt. Toll
                             Bridge Comn., Bridge
                             Rev.,
A                 3,050(D)@@ 7.875%, 7/1/18.........    3,429,938
                           Delaware River Port
                             Auth. Rev.,
                             Pennsylvania & New
                             Jersey River Bridges,
Aaa               4,470    7.375%, 1/1/07,
                             A.M.B.A.C............     4,923,079
                           Edison Twnshp., Gen.
                             Oblig., A.M.B.A.C.,
Aaa              $5,390    6.00%, 1/1/08..........    $5,559,408
Aaa               1,200    5.10%, 1/1/09..........     1,112,256
                           Egg Harbor Twnshp. Sch.
                             Dist., Cert. of
                             Part.,
Aaa               1,000(D) 7.40%, 4/1/02,
                             M.B.I.A..............     1,118,790
                           Essex Cnty. Impvt.
                             Auth.,
Aaa               1,600    5.50%, 12/1/20,
                             A.M.B.A.C............     1,470,048
                           Evesham Mun. Utils.
                             Auth. Rev., Ser. B,
                             M.B.I.A.,
Aaa               2,000    7.00%, 7/1/10..........     2,131,340
                           Guam Pwr. Auth. Rev.,
BBB*              1,750    6.30%, 10/1/22, Ser.
                             A....................     1,691,813
                           Hammonton, Gen. Oblig.,
                             A.M.B.A.C.,
Aaa                 500    6.85%, 8/15/03.........       556,560
Aaa                 500    6.85%, 8/15/04.........       556,880
Aaa                 500    6.85%, 8/15/05.........       557,155
                           Howell Twnshp. Mun.
                             Utils. Auth. Rev.,
NR                  750(D) 8.60%, 1/1/14, 2nd
                             Ser..................       861,990
                           Hudson Cnty. Impvt.
                             Auth. Fac., Lease
                             Rev.,
Aaa               1,750    6.00%, 12/1/25,
                             F.G.I.C..............     1,718,290
                           Solid Waste Sys. Rev.,
BBB-*             6,500    7.10%, 1/1/20..........     6,605,950
A+*               1,500    6.10%, 7/1/20..........     1,488,270
                           Hudson Cnty. Qualified
                             Water of Jersey City,
                             Auth. Rev.
Aaa               1,200    5.00%, 12/15/17,
                             F.S.A................     1,026,264
                           Irvington Twnshp., Gen.
                             Oblig.,
Aaa                 700    5.00%, 10/1/17,
                             F.S.A................       599,095
                           Jackson Twnshp. Sch.
                             Dist., F.G.I.C.,
Aaa               1,020    6.60%, 6/1/04..........     1,116,584
Aaa                 940    6.60%, 6/1/05..........     1,027,768
Aaa               1,600    6.60%, 6/1/10..........     1,720,496
Aaa               1,600    6.60%, 6/1/11..........     1,717,936
</TABLE>
 
                                      -5-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                   
NEW JERSEY SERIES                                           
<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                  Value            
(Unaudited)     (000)          Description(a)         (Note 1)       
<C>           <C>          <S>                      <C>
                           Jersey City Swr. Auth.,
Aaa              $4,150    4.50%, 1/1/19,
                             F.G.I.C..............    $3,226,003
                           Jersey City, Gen.
                             Oblig., F.S.A.,
Aaa               4,310    9.25%, 5/15/04, Ser.
                             A,...................     5,538,738
                           Jersey City, Redev.
                             Auth. Rev., Red Dixon
                             Mill Apts. Proj.,
AAA*              5,000    6.10%, 5/1/12,
                             F.N.M.A..............     5,108,450
                           Lakewood Twnshp., Gen.
                             Oblig., F.G.I.C.,
Aaa                 450    6.60%, 12/1/04.........       494,262
Aaa                 445    6.60%, 12/1/05.........       487,960
                           Lenape Regl. High Sch.
                             Dist., Gen. Oblig.,
Aaa                 400    7.625%, 1/1/12,
                             M.B.I.A..............       476,640
                           Mercer Cnty. Impvt.
                             Auth. Rev.,
Aa1               2,500    Zero Coupon, 4/1/06....     1,311,125
Aa1               2,725    Zero Coupon, 4/1/07....     1,340,128
                           Solid Waste Site Proj.,
AAA*              1,500(D) 7.80%, 4/1/13, Ser.
                             A....................     1,641,855
                           West Windsor Twnshp.
                             Police Proj.,
Aa                1,250    6.00%, 11/15/10........     1,265,712
                           Middle Twnshp. Sch.
                             Dist.,
Aaa               1,200    7.00%, 7/15/05,
                             F.G.I.C..............     1,348,860
                           Middlesex Cnty., Gen.
                             Oblig.,
Aaa               1,000    4.60%, 7/15/02.........       964,080
                           Monmouth Cnty. Impvt.
                             Auth. Rev., Asbury
                             Park Proj.,
Baa               1,315    7.375%, 12/1/09........     1,406,826
                           Howell Twnshp. Brd. of
                             Ed. Proj. Rev.,
AA*               2,000    6.45%, 7/1/08..........     2,158,380
                           Nat'l Auth. Rev.,
AA*               4,065    6.55%, 7/1/12..........     4,350,363
                           Water & Sewage Facs
                             Rev.,
Aaa               1,600    5.00%, 2/1/13,
                             M.B.I.A..............     1,406,768
                           Wtr. Treatment Fac.,
Aaa                 750    6.875%, 8/1/12,
                             M.B.I.A..............       833,228
                           New Jersey St. Bldg.
                             Auth. Rev., Garden
                             St. Svg. Bonds,
Aa                  890    Zero Coupon, 6/15/03,
                             Ser. A...............       556,713
                           New Jersey St. Econ.
                             Dev. Auth., Amer.
                             Airlines Inc. Proj.,
Baa2             $4,000    7.10%, 11/1/31.........    $4,028,800
                           Jersey Central Pwr. &
                             Light,
Aa                  400    7.10%, 7/1/15..........       422,140
                           Mkt. Transition Fac.
                             Rev., Sr.
                             Lien, Ser. A,
                             M.B.I.A.,
Aaa               2,000    5.80%, 7/1/08..........     1,994,140
Aaa               2,250    5.80%, 7/1/09..........     2,238,705
                           Nat'l. Assoc. of
                             Accountants,
NR                1,050    7.50%, 7/1/01..........     1,110,606
NR                  950    7.65%, 7/1/09..........       998,963
                           Natural Gas Facs. Rev.,
A2                1,000    7.25%, 3/1/21, Ser.
                             B....................     1,066,300
                           St. Barnabas Reality
                             Project,
Aaa               3,000    5.25%, 7/1/20,
                             M.B.I.A..............     2,634,960
                           New Jersey St. Econ.
                             Dist. Heating &
                             Cool., Trigen Trenton
                             Proj.,
BBB-*             2,725    6.20%, 12/1/07, Ser.
                             B....................     2,737,807
BBB-*               600    6.20%, 12/1/10.........       592,074
                           New Jersey St. Edl.
                             Facs. Fin. Auth.
                             Rev., Inst. For
                             Advanced Study,
Aaa               5,620    6.35%, 7/1/21, Ser.
                             B....................     5,729,534
                           Ramapo College, Ser. E,
                             M.B.I.A.,
Aaa               1,170    5.35%, 7/1/07..........     1,143,383
Aaa               1,240    5.40%, 7/1/08..........     1,205,776
                           Seton Hall Univ. Proj.,
Aaa                 680    6.25%, 7/1/07, Ser. B,
                             M.B.I.A..............       707,513
Baa               2,900    7.00%, 7/1/21, Ser.
                             D....................     3,037,576
                           Trenton St. Coll.,
Aaa               3,750    6.00%, 7/1/19,
                             A.M.B.A.C............     3,720,862
                           New Jersey St. Hlth.
                             Care Facs. Fin. Auth.
                             Rev.,
                             Atlantic City Med.
                             Ctr.,
A                 4,150    6.80%, 7/1/11, Ser.
                             C....................     4,315,294
</TABLE>
 
                                      -6-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                   
NEW JERSEY SERIES                                           
<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                  Value            
(Unaudited)     (000)          Description(a)         (Note 1)       
<C>           <C>          <S>                      <C>
                           New Jersey St. Hlth.
                             Care Facs. Fin. Auth.
                             Rev.,
                           Burdette Tomlin Mem. Hosp.,
Aaa              $1,000(D) 8.125%, 7/1/12, Ser. C,
                           F.G.I.C.,..............    $1,109,560
                           Deborah Heart & Lung
                             Ctr.,
Baa1              1,000    6.20%, 7/1/13..........       972,850
Baa1              1,100    6.30%, 7/1/23..........     1,061,676
                           East Orange Gen. Hosp.,
BBB+*             2,250    7.75%, 7/1/20, Ser.
                             B....................     2,376,428
                           Helene Fuld Med. Ctr.,
A*                2,700    8.00%, 7/1/08, Ser.
                             C....................     2,971,998
A*                  500    8.125%, 7/1/13, Ser.
                             C....................       553,785
                           Intercare Hlth. Systems-JFK
                             Ctr.,
A                 1,000    7.50%, 7/1/07..........     1,082,230
A                 1,000    7.625%, 7/1/18.........     1,072,510
                           Jersey Shore Med. Ctr.
Aaa               1,465    6.00%, 7/1/09,
                             A.M.B.A.C............     1,473,468
Aaa               1,500    6.25%, 7/1/21..........     1,502,310
                           Kensington Cmnty. Med.
                             Ctr.,
Aaa               3,700    7.00%, 7/1/20,
                             M.B.I.A..............     3,971,543
                           Shore Mem. Hosp., Ser.
                             C,
Aaa               3,000(D) 7.875%, 7/1/07,
                             M.B.I.A..............     3,312,360
                           St. Claires Riverside
                             Med. Ctr.,
Aaa               1,750(D) 7.60%, 7/1/02, Ser. D,
                             B.I.G................     1,918,088
Aaa               1,380(D) 7.75%, 7/1/14,
                             B.I.G................     1,517,986
                           St. Peters Med. Ctr.,
                             M.B.I.A.,
Aaa               1,725(D) 6.50%, 7/1/07, Ser.
                             E....................     1,887,167
                           New Jersey St. Hsg. &
                             Mtge. Fin. Agcy.,
                             M.B.I.A.
Aaa               6,560    7.70%, 10/1/29, Ser.
                             D....................     6,823,450
                           Multi-family Hsg. Rev.,
AAA*              8,000    7.00%, 5/1/30,
                             F.H.A................     8,188,800
                           Tiffany Manor,
A+*               2,190    6.75%, 11/1/11, Ser.
                             B....................     2,262,182
                           New Jersey St. Hwy.
                             Auth.,
                             Garden St. Pkwy. Gen.
                             Rev.,
A1                3,035    6.20%, 1/1/10..........     3,094,941
Aaa               4,365(D) 7.25%, 1/1/16..........     4,836,900
                           New Jersey St. Tpke.
                             Auth. Rev.,
A                $2,000    6.75%, 1/1/08, Ser.
                             A....................    $2,122,560
A                 1,000    6.50%, 1/1/09, Ser.
                             C....................     1,065,390
A                14,835    6.50%, 1/1/16, Ser.
                             C....................    15,572,596
                           New Jersey St.
                             Trans.Trust Fund
                             Auth.,
Aa                2,000    6.00%, 6/15/02, Ser.
                             A....................     2,096,000
                           New Jersey St.
                             Wastewater Treatment,
                             Trust Loan Rev.,
Aa                1,000    6.875%, 6/15/06........     1,084,440
Aa                7,090    6.875%, 6/15/08........     7,633,874
Aa                1,000    6.00%, 7/1/09, Ser.
                             A....................     1,010,130
                           North Brunswick
                             Twnshp., Brd. of Ed.,
AA*                 350    6.80%, 6/15/06.........       387,121
AA*                 350    6.80%, 6/15/07.........       385,924
                           Rict Hosp. Rev.,
Aa                2,000    6.40%, 5/15/10.........     2,109,460
                           Old Bridge Twnshp. Mun.
                             Utils. Auth., Sys.
                             Rev.,
Aaa               1,000(D) 8.00%, 11/1/16,
                             F.G.I.C..............     1,091,070
                           Paterson Cnty.,
Aaa               2,000    6.50%, 2/15/05,
                             F.S.A................     2,134,240
                           Pennsauken Twnshp.,
                             Brd. of Ed., Cert. of
                             Part.,
Aaa               1,030    7.70%, 7/15/09,
                             B.I.G................     1,159,069
                           Pequannock Twnshp. Brd.
                             of Ed., Cert. of
                             Part.,
Aaa                 750    7.875%, 3/1/08,
                             B.I.G................       803,070
                           Port Auth. of New York
                             & New Jersey,
A1                3,505    5.00%, 7/15/15, Ser.
                             92...................     3,019,698
A1                1,000    5.20%, 9/1/18, Ser.
                             85...................       875,950
A1                2,000    5.00%, 7/15/23, Ser.
                             92...................     1,669,800
A1                5,300    7.125%, 6/1/25, Ser.
                             69...................     5,807,157
                           Puerto Rico Comnwlth.,
                             Gen. Oblig.,
Aaa               3,000    5.40%, 7/1/07,
                             M.B.I.A..............     2,985,990
Aaa               3,000    5.50%, 7/1/08,
                             M.B.I.A..............     2,999,850
Aaa               1,000    7.00%, 7/1/10,
                             M.B.I.A..............     1,121,990
Aaa               4,000    7.00%, 7/1/10,
                             A.M.B.A.C............     4,487,960
</TABLE>
 
                                      -7-     See Notes to Financial Statements.

<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                   
NEW JERSEY SERIES                                           
<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                  Value            
(Unaudited)     (000)          Description(a)         (Note 1)       
<C>           <C>          <S>                      <C>
                           Puerto Rico Elec. Pwr.
                             Auth. Rev. Ref.,
Baa1             $2,300    6.125%, 7/1/08, Ser.
                             S....................    $2,376,843
Baa1              1,500(D) 8.40%, 7/1/15, Ser.
                             L....................     1,677,720
                           Puerto Rico Hsg. Fin.
                             Auth. Rev.,
                             Multifamily Mtge.,
AA*                 625    7.50%, 4/1/22..........       650,531
                           Sngl. Fam. Mtge.,
Baa               1,785    5.125%, 12/1/05........     1,673,652
Baa               1,000    5.25%, 12/1/06.........       934,660
                           Puerto Rico Hsg. Fin.
                             Corp., Bank & Fin.
                             Agcy.,
Baa               2,475    5.125%, 12/1/05........     2,320,610
                           Puerto Rico Hwy. Auth.
                             Rev.,
Baa1              1,000    6.75%, 7/1/05, Ser.
                             R....................     1,088,150
AAA*              2,000(D) 7.75%, 7/1/10, Ser.
                             Q....................     2,318,340
Baa1              5,550(D) 7.75%, 7/1/16, Ser.
                             Q....................     6,433,393
Baa1                750(D) 6.50%, 7/1/22, Ser.
                             S....................       825,638
                           Puerto Rico Pub. Bldgs.
                             Auth.,
                             Pub. Ed. & Hlth.
                             Facs.,
Aaa               5,500(D) 7.875%, 7/1/16, Ser.
                             H....................     6,088,170
Aaa               3,750(D) 6.875%, 7/1/21, Ser.
                             L....................     4,218,112
                           Puerto Rico Tel. Auth.
                             Rev.,
Aaa               7,875 D)(D) 7.133%, 1/25/07, Ser.
                             I,
                           M.B.I.A................     7,382,812
A                 2,000    5.50%, 1/1/22, Ser.
                             I....................     1,821,440
                           Rutgers St. Univ. Rev.,
A1                2,000    5.10%, 5/1/05, Ser.
                             S....................     1,945,360
Aaa               1,500(D)@ 8.10%, 5/1/07, Ser.
                             A....................     1,657,545
A1                2,810    6.85%, 5/1/12, Ser.
                             P....................     2,990,739
A1                5,000    6.40%, 5/1/13, Ser.
                             A....................     5,210,700
                           Sayreville, Hsg. Dev.
                             Corp., Mtge. Rev.,
AAA*              1,990    7.75%, 8/1/24,
                             F.H.A................     2,079,550
                           South Brunswick
                             Twnshp., Wtr. & Swr.
                             Utils., Gen. Impvt.,
Aa                  850    6.90%, 8/1/05..........       944,945
Aa                  850    6.90%, 8/1/06..........       944,945
                           Stony Brook Regl. Swr.
                             Auth. New Jersey
                             Rev.,
AA               $2,895    5.45%, 12/1/12, Ser.
                             B....................    $2,695,245
                           Union Cnty. Utils.
                             Auth.,
                             Solid Waste Rev.,
                             Ser. A,
A-*               1,255    7.10%, 6/15/06.........     1,302,288
A-*               6,850    7.20%, 6/15/14.........     7,057,281
                           Virgin Islands Port
                             Auth., Marine Div.
                             Rev.,
NR                1,330    10.125%, 11/1/05, Ser.
                             A....................     1,433,461
                           Virgin Islands Pub.
                             Fin. Auth. Rev., Hwy.
                             Trans. Trust Fund,
BBB*              2,750    7.70%, 10/1/04.........     3,005,393
                           Virgin Islands Terr.,
                             Hugo Ins. Claims Fund
                             Proj.,
NR                2,070    7.75%, 10/1/06, Ser.
                             91...................     2,263,400
                           Virgin Islands Wtr. &
                             Pwr. Auth., Wtr. Sys.
                             Rev.,
NR                1,400    8.50%, 1/1/10, Ser.
                             A....................     1,537,984
                           West Morris Regl. High
                             Sch. Dist., Cert. of
                             Part.,
Aaa               1,500    7.50%, 3/15/09,
                             B.I.G................     1,666,425
                           West New York & New
                             Jersey, Mun. Utils.,
                             Auth. Swr. Rev.,
                             F.G.I.C.,
Aaa               3,540    Zero Coupon,
                             12/15/06.............     1,800,019
Aaa               1,410    Zero Coupon,
                             12/15/12.............       481,656
Aaa               2,910    Zero Coupon,
                             12/15/13.............       930,327
                                                    ------------
                           Total long-term
                             investments
                             (cost
                             $318,743,174)........   330,560,269
                                                    ------------
</TABLE>
 
                                      -8-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND           
NEW JERSEY SERIES                                           
<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                  Value
(Unaudited)     (000)          Description(a)         (Note 1)
<C>           <C>          <S>                      <C>
                           SHORT-TERM INVESTMENTS--1.3%
                           Port Auth. of New York
                             & New Jersey, Spec.
                             Oblig. Rev.,
                             F.R.D.D.,
                           3.30%, 9/1/94, Ser.1
VMIG1            $4,500    (cost $4,500,000)......    $4,500,000
                                                    ------------
                           Total Investments--99.1%
                           (cost $323,243,174;
                             Note 4)..............   335,060,269
                           Other assets in excess
                             of
                             liabilities--0.9%....     3,030,153
                                                    ------------
                           Net Assets--100%.......  $338,090,422
                                                    ------------
                                                    ------------
</TABLE>
 
- ------------------
(a) The following abbreviations are used in portfolio descriptions:
    A.M.B.A.C.--American Municipal Bond Assurance Corporation.
    B.I.G.--Bond Investors Guaranty Insurance Company.
    F.G.I.C.--Financial Guaranty Insurance Company.
    F.H.A.--Federal Housing Administration.
    F.R.D.D.--Floating Rate (Daily) Demand Note #.
    F.S.A.--Financial Security Assurance.
    M.B.I.A.--Municipal Bond Insurance Association.
    F.N.M.A.--Federal National Mortgage Association.
   # For purposes of amortized cost valuation, the
     maturity date of Floating Rate Demand Notes is
     considered to be the later of the next date on
     which the security can be redeemed at par, or the
     next date on which the rate of interest is
     adjusted.
   * Standard & Poor's Rating.
   @ Pledged as initial margin on financial futures
     contracts.
  @@ $3,050,000 par amount pledged as initial margin
     on financial futures contracts.
 (D) Prerefunded issues are secured by escrowed cash
     and/or direct U.S. guaranteed obligations.
(D)(D) Inverse floating rate bond. The coupon is
     inversely indexed to a floating interest rate.
     The rate shown is the rate at period end.
 
NR--Not Rated by Moody's or Standard & Poor's.
The Fund's current Statement of Additional Information contains a description of
Moody's and Standard & Poor's ratings.
                                      -9-     See Notes to Financial Statements.

<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW JERSEY SERIES
 Statement of Assets and Liabilities
<TABLE>
<CAPTION>
Assets                                                                                     August 31, 1994
                                                                                          -----------------
<S>                                                                                       <C>
Investments, at value (cost $323,243,174)..............................................     $ 335,060,269
Cash...................................................................................            58,351
Interest receivable....................................................................         4,571,316
Receivable for Fund shares sold........................................................           547,496
Deferred expenses and other assets.....................................................             6,110
                                                                                          -----------------
    Total assets.......................................................................       340,243,542
                                                                                          -----------------
Liabilities
Payable for Fund shares reacquired.....................................................         1,533,259
Dividends payable......................................................................           285,075
Due to Distributors....................................................................           139,140
Due to Manager.........................................................................           108,144
Accrued expenses.......................................................................            64,773
Due to broker--variation margin payable................................................            21,719
Deferred trustees' fees................................................................             1,010
                                                                                          -----------------
    Total liabilities..................................................................         2,153,120
                                                                                          -----------------
Net Assets.............................................................................     $ 338,090,422
                                                                                          -----------------
                                                                                          -----------------
Net assets were comprised of:
  Shares of beneficial interest, at par................................................     $     312,787
  Paid-in capital in excess of par.....................................................       329,008,551
                                                                                          -----------------
                                                                                              329,321,338
  Accumulated net realized loss on investments.........................................        (3,005,261)
  Net unrealized appreciation on investments...........................................        11,774,345
                                                                                          -----------------
  Net assets, August 31, 1994..........................................................     $ 338,090,422
                                                                                          -----------------
                                                                                          -----------------
Class A:
  Net asset value and redemption price per share ($14,773,509 / 1,366,763 shares of
    beneficial interest issued and outstanding)........................................            $10.81
  Maximum sales charge (3.0% of offering price)........................................               .33
                                                                                          -----------------
  Maximum offering price to public.....................................................            $11.14
                                                                                          -----------------
                                                                                          -----------------
Class B:
  Net asset value, offering price and redemption price per share ($323,077,216 /
    29,889,734 shares of beneficial interest issued and outstanding)...................            $10.81
                                                                                          -----------------
                                                                                          -----------------
Class C:
  Net asset value, offer price and redemption price per share ($239,697 / 22,176 shares
    of
    beneficial interest issued and outstanding)........................................            $10.81
                                                                                          -----------------
                                                                                          -----------------
</TABLE>
 
See Notes to Financial Statements.
                                      -10-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW JERSEY SERIES
 Statement of Operations
<TABLE>
<CAPTION>
                                          Year Ended
Net Investment Income                   August 31, 1994
                                        ---------------
<S>                                     <C>
Income
  Interest...........................    $   21,572,767
                                        ---------------
Expenses
  Management fee, net of waiver of
  $449,095...........................         1,347,284
  Distribution fee--Class A..........            15,334
  Distribution fee--Class B..........         1,719,706
  Transfer agent's fees and
  expenses...........................           131,000
  Custodian's fees and expenses......           105,000
  Reports to shareholders............            71,000
  Registration fees..................            31,000
  Legal fees.........................            15,000
  Audit fee..........................            10,500
  Insurance expense..................             9,500
  Trustees' fees.....................             3,375
  Miscellaneous......................            14,444
                                        ---------------
    Total expenses...................         3,473,143
                                        ---------------
Net investment income................        18,099,624
                                        ---------------
Realized and Unrealized
Gain (Loss) on Investments
Net realized loss on:
  Investment transactions............          (628,763)
  Financial futures contract
  transactions.......................          (493,700)
  Options............................          (172,482)
                                        ---------------
                                             (1,294,945)
                                        ---------------
Net change in unrealized
  appreciation/depreciation on:
  Investments........................       (23,336,875)
  Financial futures contracts........            39,750
                                        ---------------
                                            (23,297,125)
                                        ---------------
Net loss on investments..............       (24,592,070)
                                        ---------------
Net Decrease in Net Assets
Resulting from Operations............    $   (6,492,446)
                                        ---------------
                                        ---------------
</TABLE>
 
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW JERSEY SERIES
 Statement of Changes in Net Assets
<TABLE>
<CAPTION>
                              Year Ended August 31,
Increase (Decrease) in     ----------------------------
Net Assets                     1994            1993
                           ------------    ------------
<S>                        <C>             <C>
Operations
  Net investment
  income.................  $ 18,099,624    $ 17,308,485
  Net realized gain
    (loss) on investment
    transactions.........    (1,294,945)      4,417,042
  Net change in
    unrealized
appreciation/depreciation
    of investments.......   (23,297,125)     16,729,314
                           ------------    ------------
  Net increase (decrease)
    in net assets
    resulting from
    operations...........    (6,492,446)     38,454,841
                           ------------    ------------
Dividends and distributions (Note 1)
  Dividends from net
    investment income
    Class A..............      (831,601)       (755,963)
    Class B..............   (17,267,981)    (16,552,522)
    Class C..............           (42)             --
                           ------------    ------------
                            (18,099,624)    (17,308,485)
                           ------------    ------------
  Distributions from net realized
    gains
    Class A..............      (237,645)       (130,182)
    Class B..............    (5,452,932)     (3,218,353)
                           ------------    ------------
                             (5,690,577)     (3,348,535)
                           ------------    ------------
Series share transactions
  (Note 5)
  Net proceeds from
    shares sold..........    41,819,711      66,639,119
  Net asset value of
    shares issued in
    reinvestment of
    dividends and
    distributions........    14,387,672      12,440,617
  Cost of shares
    reacquired...........   (55,213,009)    (37,221,332)
                           ------------    ------------
  Net increase in net
    assets from Series
    share transactions...       994,374      41,858,404
                           ------------    ------------
Total increase
  (decrease).............   (29,288,273)     59,656,225
Net Assets
Beginning of year........   367,378,695     307,722,470
                           ------------    ------------
End of year..............  $338,090,422    $367,378,695
                           ------------    ------------
                           ------------    ------------
</TABLE>
 
See Notes to Financial Statements.        See Notes to Financial Statements.
                                      -11-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW JERSEY SERIES
 Notes to Financial Statements
   Prudential Municipal Series Fund (the ``Fund'') is registered under the
Investment Company Act of 1940, as an open-end investment company. The Fund was
organized as a Massachusetts business trust on May 18, 1984, and consists of
seventeen series. The monies of each series are invested in separate,
independently managed portfolios. The New Jersey Series (the ``Series'')
commenced investment operations in March 1988. The Series is diversified and
seeks to achieve its investment objective of obtaining the maximum amount of
income exempt from federal and applicable state income taxes with the minimum of
risk by investing in ``investment grade'' tax-exempt securities whose ratings
are within the four highest ratings categories by a nationally recognized
statistical rating organization or, if not rated, are of comparable quality. The
ability of the issuers of the securities held by the Series to meet their
obligations may be affected by economic or political developments in a specific
state, industry or region.
                              
Note 1. Accounting            The following is a summary
Policies                              of significant accounting poli-
                              cies followed by the Fund, and the Series, in the
preparation of its financial statements.
Securities Valuations: The Fund values municipal securities (including
commitments to purchase such securities on a ``when-issued'' basis) on the basis
of prices provided by a pricing service which uses information with respect to
transactions in bonds, quotations from bond dealers, market transactions in
comparable securities and various relationships between securities in
determining values. If market quotations are not readily available from such
pricing service, a security is valued at its fair value as determined under
procedures established by the Trustees.
   Short-term securities which mature in more than 60 days are valued at current
market quotations. Short-term securities which mature in 60 days or less are
valued at amortized cost which approximates market value.
   All securities are valued as of 4:15 P.M., New York time.
Financial Futures Contracts: A financial futures contract is an agreement to
purchase (long) or sell (short) an agreed amount of debt securities at a set
price for delivery on a future date. Upon entering into a financial futures
contract, the Series is required to pledge to the broker an amount of cash
and/or other assets equal to a certain percentage of the contract amount. This
amount is known as the ``initial margin''. Subsequent payments, known as
``variation margin'', are made or received by the Series each day, depending on
the daily fluctuations in the value of the underlying security. Such variation
margin is recorded for financial statement purposes on a daily basis as
unrealized gain or loss. The Series invests in financial futures contracts
solely for the purpose of hedging its existing portfolio securities or
securities the Series intends to purchase against fluctuations in value caused
by changes in prevailing market interest rates. Should interest rates move
unexpectedly, the Series may not achieve the anticipated benefits of the
financial futures contracts and may realize a loss. The use of futures
transactions involves the risk of imperfect correlation in movements in the
price of futures contracts, interest rates and the underlying hedged assets.
Option Writing: When the Fund writes an option, an amount equal to the premium
received by the Fund is recorded as a liability and is subsequently adjusted to
the current market value of the option written. Premiums received from writing
options which expire unexercised are treated by the Fund on the expiration date
as realized gains from securities or currencies based upon the type of option
written. The difference between the premium and the amount paid on effecting a
closing purchase transaction, including brokerage commissions, is also treated
as a realized gain, or if the premium received is less than the amount paid for
the closing purchase transaction, as a realized loss. If a call option is
exercised, the premium is added to the proceeds from the sale of the underlying
security or currency in determining whether the Fund has realized a gain or
loss. If a put option is exercised, the premium reduces the cost basis of the
securities or currencies purchased by the Fund. The Fund as writer of an option
may have no control over whether the underlying securities may be sold (call) or
purchased (put) and as a result bears the market risk of an unfavorable change
in the price of the security underlying the written option. There were no
written options outstanding at August 31, 1994.
Securities Transactions and Investment Income: Securities transactions are
recorded on the trade date. Realized gains and losses on sales of securities are
calculated on the identified cost basis. Interest income is recorded on the
accrual basis. The Series amortizes premiums and original
                                      -12-
 <PAGE>
<PAGE>
issue discount paid on purchases of portfolio securities as adjustments to
interest income.
   Net investment income (other than distribution fees) and unrealized and
realized gains or losses are allocated daily to each class of shares based upon
the relative proportion of net assets of each class at the beginning of the day.
Federal Income Taxes: For federal income tax purposes, each series in the Fund
is treated as a separate taxpaying entity. It is the intent of the Series to
continue to meet the requirements of the Internal Revenue Code applicable to
regulated investment companies and to distribute all of its net income to
shareholders. For this reason and because substantially all of the Series' gross
income consists of tax-exempt interest, no federal income tax provision is
required.
Dividends and Distributions: The Series declares daily dividends from net
investment income. Payment of dividends is made monthly. Distributions of net
capital gains, if any, are made annually.
   Income distributions and capital gain distributions are determined in
accordance with income tax regulations which may differ from generally accepted
accounting principles. These differences are primarily due to differing
treatments for short-term capital gains and market discount.
                              
Note 2. Agreements            The Fund has a management
                              agreement with Prudential Mutual Fund Management,
Inc. (``PMF''). Pursuant to this agreement, PMF has responsibility for all
investment advisory services and supervises the subadviser's performance of such
services. PMF has entered into a subadvisory agreement with The Prudential
Investment Corporation (``PIC''). PIC furnishes investment advisory services in
connection with the management of the Fund. PMF pays for the services of PIC,
the cost of compensation of officers of the Fund, occupancy and certain clerical
and bookkeeping costs of the Fund. The Fund bears all other costs and expenses.
   The management fee paid PMF is computed daily and payable monthly, at an
annual rate of .50 of 1% of the average daily net assets of the Series. During
the year ended August 31, 1994, PMF waived 25% of its management fee. The amount
of fees waived for the year ended August 31, 1994, amounted to $449,095 ($0.014
per share; 0.13% of average net assets). The Series is not required to reimburse
PMF for such waiver.
   The Fund has distribution agreements with Prudential Mutual Fund
Distributors, Inc. (``PMFD''), which acts as the distributor of the Class A
shares of the Fund, and with Prudential Securities Incorporated (``PSI''), which
acts as distributor of the Class B and Class C shares of the Fund (collectively
the ``Distributors''). The Fund compensates the Distributors for distributing
and servicing the Fund's Class A, Class B and Class C shares, pursuant to plans
of distribution, (the ``Class A, B and C Plans'') regardless of expenses
actually incurred by them. The distribution fees are accrued daily and payable
monthly.
   On July 19, 1994, shareholders of the Fund approved amendments to the Class A
and Class B distribution plans under which the distribution plans became
compensation plans, effective August 1, 1994. Prior thereto, the distribution
plans were reimbursement plans, under which PMFD and PSI were reimbursed for
expenses actually incurred by them up to the amount permitted under the Class A
and Class B Plans, respectively. The Fund is not obligated to pay any prior or
future excess distribution costs (costs incurred by the Distributors in excess
of distribution fees paid by the Fund or contingent deferred sales charges
received by the Distributors). The rate of the distribution fees charged to
Class A and Class B shares of the Fund did not change under the amended plans of
distribution. The Fund began offering Class C shares on August 1, 1994.
   Pursuant to the Class A, B and C Plans, the Fund compensates the Distributors
for distribution-related activities at an annual rate of up to .30 of 1%, .50 of
1% and 1%, of the average daily net assets of the Class A, B and C shares,
respectively. Such expenses under the Plans were .10 of 1%, .50 of 1% and .75 of
1% of the average daily net assets of the Class A, B and C shares, respectively,
for the fiscal year ended August 31, 1994.
   PMFD has advised the Series that it has received approximately $94,600 in
front-end sales charges resulting from sales of Class A shares during the fiscal
year ended August 31, 1994. From these fees, PMFD paid such sales charges to PSI
and Pruco Securities Corporation, affiliated broker-dealers, which in turn paid
commissions to salespersons and incurred other distribution costs.
   PSI has advised the Series that for the fiscal year ended August 31, 1994, it
received approximately $447,600 in contingent deferred sales charges imposed
upon certain redemptions by Class B and Class C (per Note 5) shareholders.
   PMFD is a wholly-owned subsidiary of PMF; PSI, PMF and PIC are indirect,
wholly-owned subsidiaries of The Prudential Insurance Company of America.
                                      -13-
 <PAGE>
<PAGE>
                              
Note 3. Other                 Prudential Mutual Fund Ser-
Transactions                  vices, Inc. (``PMFS''), a 
with Affiliates               wholly-owned subsidiary of 
                              PMF, serves as the Fund's transfer agent and
during the year ended August 31, 1994, the Series incurred fees of approximately
$116,700 for the services of PMFS. As of August 31, 1994, approximately $9,400
of such fees were due to PMFS. Transfer agent fees and expenses in the Statement
of Operations include certain out-of-pocket expenses paid to non-affiliates.

                              
Note 4. Portfolio             Purchases and sales of port-
Securities                    folio securities of the Series, 
                              excluding short-term investments, for the year
ended August 31, 1994, were $119,491,311 and $117,750,762, respectively.
   At August 31, 1994 the Series sold 50 financial futures contracts on the
Municipal Bond Index which expire in September 1994 and sold 35 financial
futures contracts on U.S. Treasury Bonds which expire in December 1994. The
value at disposition of such contracts was $8,133,969. The value of such
contracts on August 31, 1994 was $8,176,719, thereby resulting in an unrealized
loss of $42,750.
   The federal income tax basis of the Series' investments at August 31, 1994,
was $323,255,449 and, accordingly, net unrealized appreciation for federal
income tax purposes was $11,804,820 (gross unrealized appreciation-$15,604,377;
gross unrealized depreciation-$3,799,557).
   The Fund will elect to treat net capital losses of approximately $2,941,904
incurred in the ten month period ended August 31, 1994 as having been incurred
in the following fiscal year.
                              
Note 5. Capital               The Series currently offers
                              Class A, Class B and Class C shares. Class A
shares are sold with a front-end sales charge of up to 3.0%. Class B shares are
sold with a contingent deferred sales charge which declines from 5% to zero
depending on the period of time the shares are held. Class C shares are sold
with a contingent deferred sales charge of 1% during the first year. Class B
shares will automatically convert to Class A shares on a quarterly basis
approximately seven years after purchase commencing on or about February 1995.
The Fund has authorized an unlimited number of shares of beneficial interest of
each class at $.01 par value per share.
   Transactions in shares of beneficial interest were as follows:
<TABLE>
<CAPTION>
Class A                              Shares        Amount
                                   ----------   ------------
<S>                                <C>          <C>
Year ended August 31, 1994:
Shares sold......................     314,116   $  3,550,381
Shares issued in reinvestment
  of dividends and
  distributions..................      62,184        699,684
Shares reacquired................    (329,592)    (3,698,430)
                                   ----------   ------------
Net increase in shares
  outstanding....................      46,708   $    551,635
                                   ----------   ------------
                                   ----------   ------------
Year ended August 31, 1993:
Shares sold......................     481,101   $  5,443,721
Shares issued in reinvestment
  of dividends and
  distributions..................      49,263        555,537
Shares reacquired................    (280,954)    (3,184,387)
                                   ----------   ------------
Net increase in shares
  outstanding....................     249,410   $  2,814,871
                                   ----------   ------------
                                   ----------   ------------
Class B
Year ended August 31, 1994:
Shares sold......................   3,349,228   $ 38,030,222
Shares issued in reinvestment
  of dividends and
  distributions..................   1,214,942     13,687,960
Shares reacquired................  (4,642,077)   (51,514,579)
                                   ----------   ------------
Net decrease in shares
  outstanding....................     (77,907)  $    203,603
                                   ----------   ------------
                                   ----------   ------------
Year ended August 31, 1993:
Shares sold......................   5,414,811   $ 61,195,397
Shares issued in reinvestment
  of dividends and
  distributions..................   1,055,089     11,885,079
Shares reacquired................  (3,024,547)   (34,036,945)
                                   ----------   ------------
Net increase in shares
  outstanding....................   3,445,353   $ 39,043,531
                                   ----------   ------------
                                   ----------   ------------
Class C
August 1, 1994* through
  August 31, 1994:
Shares sold......................      22,173   $    239,108
Shares issued in reinvestment
  of dividends...................           3             28
Shares reacquired................          --             --
                                   ----------   ------------
Net increase in shares
  outstanding....................      22,176   $    239,136
                                   ----------   ------------
                                   ----------   ------------
- ---------------
* Commencement of offering of Class C shares.
</TABLE>
                                      -14-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW JERSEY SERIES
 Financial Highlights
<TABLE>
<CAPTION>
                             Class A                                                                                    Class C
     -------------------------------------------------------                         Class B                          -----------
                                                 January 22,   ----------------------------------------------------    August 1,
                                                   1990(D)                                                            1994(D)(D)
               Year Ended August 31,               through                    Year Ended August 31,                     through
     -----------------------------------------   August 31,    ----------------------------------------------------   August 31,
         1994        1993      1992      1991       1990         1994       1993       1992       1991       1990        1994
     ------------   -------   -------   ------   -----------   --------   --------   --------   --------   --------   -----------
<S>  <C>            <C>       <C>       <C>      <C>           <C>        <C>        <C>        <C>        <C>        <C>
PER
SHARE
OPERATING
  PERFORMANCE:
Net
asset
value,
  beginning
  of
  period. $ 11.74   $ 11.15   $ 10.73   $10.16     $ 10.30     $ 11.74    $  11.15   $  10.73   $  10.16   $  10.33     $ 10.83
     ------------   -------   -------   ------   -----------   --------   --------   --------   --------   --------   -----------
Income
  from
  investment
  operations
Net
investment
income@...    .61       .64       .67      .69         .41         .56         .59        .63        .65        .67         .04
Net
realized
  and
  unrealized
  gain
  (loss) on
  investment
  trans-
  actions..  (.75)      .71       .51      .59        (.14)       (.75)        .71        .51        .59       (.14)       (.02)
     ------------   -------   -------   ------   -----------   --------   --------   --------   --------   --------   -----------
  Total
   from
   investment
    oper-
    ations.. (.14)     1.35      1.18     1.28         .27        (.19)       1.30       1.14       1.24        .53         .02
     ------------   -------   -------   ------   -----------   --------   --------   --------   --------   --------   -----------
Less
distributions
Dividends
  from
  net
  investment
  income...  (.61)     (.64)     (.67)    (.69)       (.41)       (.56)      (.59)      (.63)      (.65)      (.67)        (.04)
Distributions
  from net
  realized
  gains on
  investment
  trans-
  actions..  (.18)     (.12)     (.09)    (.02)        --         (.18)      (.12)      (.09)      (.02)      (.03)         --
     ------------   -------   -------   ------   -----------   --------   --------   --------   --------   --------   -----------
  Total
  distri-
  butions..  (.79)     (.76)     (.76)    (.71)       (.41)       (.74)      (.71)      (.72)      (.67)      (.70)      (.04)
     ------------   -------   -------   ------   -----------   --------   --------   --------   --------   --------   -----------
Net
asset
value,
  end
  of
  period.$  10.81   $ 11.74   $ 11.15   $10.73     $ 10.16     $ 10.81    $  11.74   $  11.15   $  10.73   $  10.16     $ 10.81
     ------------   -------   -------   ------   -----------   --------   --------   --------   --------   --------   -----------
     ------------   -------   -------   ------   -----------   --------   --------   --------   --------   --------   -----------
TOTAL
RETURN#:.   (1.27)%   12.57%    11.35%   12.96%       2.70%      (1.67)%    12.12%     10.93%     12.52%      5.28%      0.14%
RATIOS/SUPPLEMENTAL
  DATA:
Net
assets,
  end
  of
 period
 (000).$ 14,774     $15,501   $11,941   $8,041     $ 3,616     $323,077   $351,878   $295,781   $244,322   $180,636     $   240
Average
  net
 assets
 (000).$ 15,334     $13,444   $ 9,759   $5,637     $ 1,902     $343,941   $316,372   $269,318   $208,893   $155,162     $    11
Ratios
  to
  average
  net
  assets:@##
  Expenses,
  including
    distribution
    fees...   .58%      .61%      .48%     .29%        .20%*       .98%      1.01%       .88%       .69%       .50%      1.29%*
  Expenses,
  excluding
    distribution
    fees...   .48%      .51%      .38%     .19%        .10%*       .48%       .51%       .38%       .19%       .10%        .54%*
Net
investment
 income...   5.42%     5.63%     6.14%    6.58%       6.79%*      5.02%      5.23%      5.74%      6.18%      6.50%       5.06%*
Portfolio
turnover...    34%       32%       38%     116%         87%         34%        32%        38%       116%        87%         34%

 
- ---------------
   * Annualized.
 (D) Commencement of offering of Class A shares.
(D)(D) Commencement of offering of Class C shares.
   @ Net of management and/or distribution fee waiver.
   # Total return does not consider the effects of sales loads. Total return is calculated assuming a purchase of shares on
     the first day and a sale on the last day of each period reported and includes reinvestment of dividends and
     distributions. Total returns for periods of less than a full year are not annualized.
  ## Because of the events referred to in (D)(D) and the timing of such, the ratios for the Class C shares are not
     necessarily comparable to that of Class A or B shares and are not necessarily indicative of future ratios.
</TABLE>

See Notes to Financial Statements.
                                      -15-
 <PAGE>
<PAGE>
                          INDEPENDENT AUDITORS' REPORT
The Shareholders and Board of Trustees
Prudential Municipal Series Fund, New Jersey Series
   We have audited the accompanying statement of assets and liabilities of
Prudential Municipal Series Fund, New Jersey Series, including the portfolio of
investments, as of August 31, 1994, the related statements of operations for the
year then ended and of changes in net assets for each of the two years in the
period then ended, and the financial highlights for each of the five years in
the period then ended. These financial statements and financial highlights are
the responsibility of the Fund's management. Our responsibility is to express an
opinion on these financial statements and financial highlights based on our
audits.
   We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements and financial
highlights are free of material misstatement. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements. Our procedures included confirmation of the securities owned as of
August 31, 1994 by correspondence with the custodian. An audit also includes
assessing the accounting principles used and significant estimates made by
management, as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.
   In our opinion, such financial statements and financial highlights present
fairly, in all material respects, the financial position of Prudential Municipal
Series Fund, New Jersey Series, as of August 31, 1994, the results of its
operations, the changes in its net assets, and its financial highlights for the
respective stated periods in conformity with generally accepted accounting
principles.
Deloitte & Touche LLP
New York, New York
October 17, 1994
                         FEDERAL INCOME TAX INFORMATION
   We are required by the Internal Revenue Code to advise you within 60 days of
the Series' fiscal year end (August 31, 1994) as to the federal tax status of
dividends paid by the Series during such fiscal year. Accordingly, we are
advising you that in the fiscal year ended August 31, 1994, dividends paid from
net investment income of $.61 per Class A share, $.56 per Class B share, and
$.04 per Class C shares were all federally tax-exempt interest dividends. In
addition, the Series paid to both Class A and B shares a long-term capital gain
distribution of $.095 per share which is taxable as such and a short-term
capital gain distribution of $.084 which is taxable as ordinary income.
   In January 1995, you will be advised on IRS Form 1099 DIV or substitute 1099
DIV as to the federal tax status of the distributions received by you in
calendar year 1994.
                                      -16-
 <PAGE>
<PAGE>
   These graphs are furnished to you in accordance with SEC regulations. They
compare a $10,000 investment in Prudential Municipal Series Fund: New Jersey
Series (Class A, Class B, and Class C) with a similar investment in the Lehman
Brothers Municipal Bond Index (the Index) by portraying the initial account
values at the commencement of operations of each class and subsequent account
values at the end of each fiscal year (August 31) beginning in 1990 for Class A,
in 1988 for Class B shares and 1994 for Class C shares. For purposes of the
graphs and, unless otherwise indicated, the accompanying tables, it has been
assumed that
(a) the maximum sales charge was deducted from the initial $10,000 investment in
Class A shares; (b) the maximum applicable contingent deferred sales charge was
deducted from the value of the investment in Class B shares and Class C shares,
assuming full redemption on August 31, 1994; (c) all recurring fees (including
management fees) were deducted; and (d) all dividends and distributions were
reinvested. Class B shares will automatically convert to Class A shares on a
quarterly basis approximately seven years after purchase. This conversion
feature is expected to be implemented on or about February 1995 and is not
reflected in the graph. The graph and accompanying tables reflect the past
subsidy and/or waiver of expenses and/or management fees. Without fee waivers
and expense subsidies, the value of a $10,000 investment in the Series and the
Series' average annual total return, as shown above, would have been lower.
   The Index is a weighted index comprised of 21,000 municipal bonds (general
obligation bonds, revenue bonds, insured bonds and prerefunded bonds) selected
by Lehman Brothers as representative of the long-term investment grade municipal
bond market. The Index is an unmanaged index and includes the reinvestment of
all income, but does not reflect the payment of transaction costs and advisory
fees associated with an investment in the Series. The securities which comprise
the Index may differ substantially from the securities in the Series' portfolio
because the Index, among other things, is not state specific. The Lehman
Brothers Municipal Bond Index is not the only index which may be used to
characterize performance of long-term, investment-grade tax-exempt bond funds
and other indexes may portray different comparative performance.

                                      -17-




























<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND               Portfolio of Investments
NEW JERSEY MONEY MARKET SERIES                          August 31, 1994

<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                   Value
(Unaudited)     (000)            Description           (Note 1)
<C>           <C>          <S>                       <C>
                           Atlantic Cnty. Impvt.
                             Auth. Rev.,
                           3.05%, 9/7/94, Ser. 86,
VMIG1          $ 1,300       F.R.W.D...............  $  1,300,000
                           Bayonne,
NR               4,475     3.29%, 9/30/94, B.A.N.,.     4,476,006
NR                 980     3.29%, 9/30/94, T.A.N.,.       980,220
                           Cape May Cnty. Mun.
                             Utils. Auth., Waste
                             Rev., M.T.,
SP1+*            4,500     2.80%, 11/30/94.........     4,500,000
                           Gloucester Cnty. Ind.
                             Poll. Ctrl.,
                             Fin. Auth. Rev.,
                             F.R.W.D.,
P1               4,610     2.70%, 9/7/94, Ser. 92..     4,610,000
P1               3,120     3.15%, 9/7/94...........     3,120,000
                           Hudson Cnty., T.A.N.,
NR               4,000     4.17%, 2/17/95..........     4,003,956
                           Hudson Cnty. Impvt.
                             Auth.,
                             Pooled Gov't. Loan
                             Prog., F.R.W.D.,
A-1*             4,445     3.45%, 9/8/94, Ser.86...     4,445,000
                           Jersey City, Gen.
                             Oblig.,
NR               8,000     3.50%, 9/30/94..........     8,002,484
                           Millburn Twnshp.,
                             T.A.N.,
NR               3,500     3.02%, 11/15/94.........     3,500,820
                           Montgomery Twnshp.,
                             B.A.N.,
NR               2,806     3.00%, 12/16/94.........     2,809,463
                           New Jersey St. Econ.
                             Dev. Auth.,
VMIG1            2,000     2.85%, 9/1/94, F.R.D.D..     2,000,000
NR               1,860     3.30%, 9/1/94, F.R.D.D..     1,860,000
VMIG1            4,115     4.10%, 9/1/94, F.R.W.D..     4,115,000
A1+*               500     3.15%, 9/7/94,
                             F.R.W.D...............       500,000
                           Applewood Ctr. for
                             Aging,
A-1*             9,050     2.95%, 9/1/94, Ser. 89..     9,050,000
                           Catholic Cmnty. Svcs
                             Proj.,
VMIG1            6,000     3.05%, 9/1/94, F.R.W.D..     6,000,000
                           Chambers Cogeneration
                             Ltd., Ser.91,
                             T.E.C.P.,
VMIG1          $ 4,400     2.80%, 9/8/94...........  $  4,400,000
VMIG1            3,000     2.85%, 9/13/94..........     3,000,000
                           Franciscan Oaks Proj.
                             Ser. B,
A1+*             1,600     2.90%, 9/7/94, F.R.W.D..     1,600,000
                           Gen. Motors Project,
VMIG2            7,350     3.10%, 9/7/94, F.R.W.D..     7,350,000
                           Hoffman Louisiana Roche
                             Inc. Proj.,
NR               7,600     3.30%, 9/1/94,
                             F.R.D.D...............     7,600,000
                           Kent Place,
                           3.05%, 9/1/94, Ser. 92L,
VMIG1            1,940       F.R.D.D...............     1,940,000
                           Marriot Corp. Proj.,
                           3.05%, 9/7/94, Ser. 84,
P1               6,700       F.R.W.D...............     6,700,000
                           Peddie Sch. Proj. Ser. B,
A-1*             3,000     3.20%, 9/1/94, F.R.D.D...    3,000,000
                           Rev. Adj. Assoc.,
Aa3              1,580     3.20%, 9/1/94, F.R.D.D...    1,580,000
                           Russ Berrie & Co.,
                           3.10%, 9/7/94, Ser. 83,
A-1*               200       F.R.W.D...............       200,000
                           New Jersey St. Hsg. &
                             Mtge.
                             Fin. Agcy., Rev.,
                             M.T.,
VMIG1            3,665     2.95%, 9/29/94..........     3,665,000
                           New Jersey St. Tpke.
                             Auth. Rev.,
                           2.95%, 9/7/94, Ser. 91D,
VMIG1            9,400       F.R.W.D...............     9,400,000
                           New Jersey St., O.T.,
VMIG1            4,700     3.75%, 2/15/95, Ser. A-4     4,700,000
                           North Brunswick Twnshp.
                             B.A.N.,
NR               3,400     3.79%, 4/7/95...........     3,403,611
                           Port Auth. of New York &
                             New Jersey,
                             KIAC Partners,
                             F.R.W.D.,
VMIG1            2,900     2.95%, 9/7/94, Ser. 3...     2,900,000
                           Spec. Oblig. Rev.,
                             F.R.D.D.,
VMIG1            3,200     3.20%, 9/1/94...........     3,200,000
VMIG1            9,200     3.30%, 9/1/94, Ser.1....     9,200,000
NR               8,000     3.1251%, 9/6/94.........     8,000,000
</TABLE>
 
                                      -4-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND
NEW JERSEY MONEY MARKET SERIES

<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                   Value
(Unaudited)     (000)            Description           (Note 1)
<C>           <C>          <S>                       <C>
                           Puerto Rico Comnwlth.,
                             Gov't. Dev. Bank.,
                             F.R.W.D.,
VMIG1          $ 1,200     2.90%, 9/7/94, Ser.
                             85....................  $  1,200,000
                           So. Brunswick Twnshp.,
                             T.A.N.,
NR               5,500     3.65%, 2/15/95..........     5,509,725
                           Union Ind. Poll. Ctrl.
                             Fin. Auth. Rev.,
                             Poll. Ctrl. Rev.,
                             T.E.C.P.,
P1               2,700     3.20%, 9/29/94..........     2,700,000
                                                     ------------
                           Total Investments--98.9%
                           (amortized
                           cost--$156,521,285**)...   156,521,285
                           Assets in excess of
                             other
                             liabilities--1.1%.....     1,758,637
                                                     ------------
                           Net Assets--100%........  $158,279,922
                                                     ------------
                                                     ------------
</TABLE>
 
- ------------------
(a) The following abbreviations are used in portfolio descriptions:
    B.A.N.--Bond Anticipation Note.
    F.R.D.D.--Floating Rate (Daily) Demand Note #.
    F.R.W.D.--Floating Rate (Weekly) Demand Note #.
    O.T.--Optional Tender.
    M.T.--Mandatory Tender.
    T.A.N.--Tax Anticipation Note.
    T.E.C.P.--Tax Exempt Commercial Paper.
 # For purposes of amortized cost valuation, the maturity date of such
   securities are considered to be the later of the next date on which the
   security can be redeemed at par, or the next date on which the rate of
   interest is adjusted.
 * Standard & Poor's rating.
** The cost of securities for federal income tax purposes is substantially the
   same as for financial reporting purposes.
NR--Not Rated by Moody's or Standard & Poor's.
The Fund's current Statement of Additional Information contains a description of
Moody's and Standard & Poor's ratings.

                                      -5-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW JERSEY MONEY MARKET SERIES
 Statement of Assets and Liabilities
<TABLE>
<CAPTION>
Assets                                                                                      August 31, 1994
                                                                                            ---------------
<S>                                                                                         <C>
Investments, at amortized cost which approximates market value...........................    $ 156,521,285
Cash.....................................................................................           69,056
Receivable for Series shares sold........................................................        3,659,882
Interest receivable......................................................................          828,999
Receivable for investments sold..........................................................          220,000
Other assets.............................................................................           12,574
                                                                                            ---------------
    Total assets.........................................................................      161,311,796
                                                                                            ---------------
Liabilities
Payable for Series shares reacquired.....................................................        2,865,662
Dividends payable........................................................................           67,128
Management fee payable...................................................................           50,719
Accrued expenses and other liabilities...................................................           38,112
Distribution fee payable.................................................................            9,243
Deferred trustees' fees..................................................................            1,010
                                                                                            ---------------
    Total liabilities....................................................................        3,031,874
                                                                                            ---------------
Net Assets...............................................................................    $ 158,279,922
                                                                                            ---------------
                                                                                            ---------------
Net assets were comprised of:
  Shares of beneficial interest, at $.01 par value.......................................    $   1,582,799
  Paid-in capital in excess of par.......................................................      156,697,123
                                                                                            ---------------
  Net assets, August 31, 1994............................................................    $ 158,279,922
                                                                                            ---------------
                                                                                            ---------------
  Net asset value, offering price and redemption price per share ($158,279,922 /
    158,279,922 shares of beneficial interest issued and outstanding; unlimited number of
    shares authorized)...................................................................            $1.00
                                                                                            ---------------
                                                                                            ---------------
</TABLE>
 
See Notes to Financial Statements.
                                      -6-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW JERSEY MONEY MARKET SERIES
 Statement of Operations
<TABLE>
<CAPTION>
                                          Year Ended
                                          August 31,
Net Investment Income                        1994
                                          ----------
<S>                                       <C>
Income
  Interest and discount earned..........  $4,316,194
                                          ----------
Expenses
  Management fees, net of waiver of
  $211,404..............................     634,212
  Distribution fee......................     211,404
  Transfer agent's fees and expenses....      88,000
  Custodian's fees and expenses.........      76,000
  Reports to shareholders...............      69,500
  Registration fees.....................      25,000
  Legal fees............................      15,000
  Audit fee.............................      10,000
  Deferred organization expenses........       6,639
  Insurance expense.....................       4,400
  Trustees' fees........................       3,375
  Miscellaneous.........................       2,672
                                          ----------
       Total expenses...................   1,146,202
                                          ----------
Net investment income...................   3,169,992
                                          ----------
Net Increase in Net Assets
Resulting from Operations...............  $3,169,992
                                          ----------
                                          ----------
</TABLE>
 
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW JERSEY MONEY MARKET SERIES
 Statement of Changes in Net Assets
<TABLE>
<CAPTION>
                              Year Ended August 31,
Increase (Decrease)       ------------------------------
in Net Assets                 1994             1993
                          -------------    -------------
<S>                       <C>              <C>
Operations
  Net investment
  income................  $   3,169,992    $   3,443,063
                          -------------    -------------
  Net increase in net
    assets resulting
    from operations.....      3,169,992        3,443,063
                          -------------    -------------
Dividends and
  distributions.........     (3,169,992)      (3,443,063)
                          -------------    -------------
Series share
  transactions
  (at $1 per share)
  Net proceeds from
    shares sold.........    556,557,575      492,846,812
  Net asset value of
    shares issued to
    shareholders in
    reinvestment of
    dividends...........      3,057,774        3,379,946
  Cost of shares
  reacquired............   (564,422,228)    (497,232,130)
                          -------------    -------------
  Net decrease in net
    assets from Series
    share
    transactions........     (4,806,879)      (1,005,372)
                          -------------    -------------
Total decrease..........     (4,806,879)      (1,005,372)
Net Assets
Beginning of year.......    163,086,801      164,092,173
                          -------------    -------------
End of year.............  $ 158,279,922    $ 163,086,801
                          -------------    -------------
                          -------------    -------------
</TABLE>
 
See Notes to Financial Statements.
                                      -7-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW JERSEY MONEY MARKET SERIES
 Notes to Financial Statements

   Prudential Municipal Series Fund (the ``Fund'') is registered under the
Investment Company Act of 1940 as an open-end investment company. The Fund was
organized as a Massachusetts business trust on May 18, 1984 and consists of
seventeen series. The monies of each series are invested in separate,
independently managed portfolios. The New Jersey Money Market Series (the
``Series'') commenced investment operations on December 3, 1990. The Series is
non-diversified and seeks to achieve its investment objective of providing the
highest level of income that is exempt from New Jersey State and federal income
taxes with a minimum of risk by investing in ``investment grade'' tax-exempt
securities maturing within 13 months or less and whose ratings are within the
two highest ratings categories by a nationally recognized statistical rating
organization, or if not rated, are of comparable quality. The ability of the
issuers of the securities held by the Series to meet their obligations may be
affected by economic developments in a specific state, industry or region.

Note 1. Accounting            The following is a summary
Policies                      of significant accounting poli-
                              cies followed by the Fund, and the Series, in the
preparation of its financial statements.

Securities Valuations: Portfolio securities of the Series are valued at
amortized cost, which approximates market value. The amortized cost method of
valuation involves valuing a security at its cost on the date of purchase and
thereafter assuming a constant amortization to maturity of any discount or
premium.
   All securities are valued as of 4:30 P.M., New York time.
Securities Transactions and Investment Income: Securities transactions are
recorded on the trade date. Realized gains and losses on sales of investments
are calculated on the identified cost basis. Interest income is recorded on the
accrual basis.

Federal Income Taxes: For federal income tax purposes, each series in the Fund
is treated as a separate taxpaying entity. It is the intent of the Series to
continue to meet the requirements of the Internal Revenue Code applicable to
regulated investment companies and to distribute all of its net income to
shareholders. For this reason and because substantially all of the Series' gross
income consists of tax-exempt interest, no federal income tax provision is
required.

Dividends: The Series declares daily dividends from net investment income.
Payment of dividends is made monthly.
   Income distributions and capital gain distributions are determined in
accordance with income tax regulations which may differ from generally accepted
accounting principles.

Deferred Organization Expenses: The Series incurred $32,200 in organization and
initial registration expenses. Such amount has been deferred and is being
amortized over a period of 60 months ending December 1995.

Note 2. Agreements            The Fund has a management
                              agreement with Prudential Mutual Fund Management,
Inc. (``PMF''). Pursuant to this agreement, PMF has responsibility for all
investment advisory services and supervises the subadviser's performance of such
services. PMF has entered into a subadvisory agreement with The Prudential
Investment Corporation (``PIC''); PIC furnishes investment advisory services in
connection with the management of the Fund. PMF pays for the cost of the
subadviser's services, the compensation of officers of the Fund, occupancy and
certain clerical and bookkeeping costs of the Fund. The Fund bears all other
costs and expenses.
   The management fee paid PMF is computed daily and payable monthly, at an
annual rate of .50 of 1% of the average daily net assets of each of the Series.
During the year ended August 31, 1994, PMF waived 25% of its managements fee.
The amount of such fees waived for the year ended August 31, 1994 amounted to
$211,404 ($.001 per share; .125% of average net assets).
   The Fund has a distribution agreement with Prudential Mutual Fund
Distributors, Inc. (``PMFD''). To reimburse PMFD for its expenses incurred
pursuant to a plan of distribution, the Fund pays PMFD a reimbursement, accrued
daily and payable monthly, at an annual rate of .125 of 1% of the Series'
average daily net assets. PMFD pays various broker-dealers, including Prudential
Securities Incorporated (``PSI'') and Pruco Securities Corporation, affiliated
broker-dealers, for account servicing fees and other expenses incurred by such
broker-dealers.
   PMFD is a wholly-owned subsidiary of PMF; PSI, PMF and PIC are (indirect)
wholly-owned subsidiaries of The Prudential Insurance Company of America.

                                      -8-
 <PAGE>
<PAGE>

Note 3. Other                 Prudential Mutual Fund Ser-
Transactions                  vices, Inc. (``PMFS''), a 
with Affiliates               wholly-owned subsidiary of 
                              PMF, serves as the Fund's transfer agent. During
the year ended August 31, 1994, the Series incurred fees of approximately
$82,500 for the services of PMFS. As of August 31, 1994, approximately $6,700 of
such fees were due to PMFS. Transfer agent fees and expenses in the Statement of
Operations include certain out-of-pocket expenses paid to non-affiliates.

                                      -9-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW JERSEY MONEY MARKET SERIES
 Financial Highlights
<TABLE>
<CAPTION>
                                                                                                              December 3,
                                                                                                                 1990*
                                                                              Year Ended August 31,             Through
                                                                        ----------------------------------    August 31,
                                                                           1994         1993        1992         1991
                                                                        ----------    --------    --------    -----------
<S>                                                                     <C>           <C>         <C>         <C>
PER SHARE OPERATING PERFORMANCE:
Net asset value, beginning of period.................................    $    1.00    $   1.00    $   1.00     $     1.00
Net investment income and net realized gains(D)......................          .02         .02         .04            .03
Dividends and distributions..........................................         (.02)       (.02)       (.04)          (.03)
                                                                        ----------    --------    --------    -----------
Net asset value, end of period.......................................    $    1.00    $   1.00    $   1.00     $     1.00
                                                                        ----------    --------    --------    -----------
                                                                        ----------    --------    --------    -----------
TOTAL RETURN#:.......................................................         1.90%       2.31%       3.48%          3.55%
RATIOS/SUPPLEMENTAL DATA:
Net assets, end of period (000)......................................    $ 158,280    $163,087    $164,092     $  117,460
Average net assets (000).............................................    $ 169,123    $170,103    $155,915     $   89,273
Ratios to average net assets(D):
  Expenses, including distribution fee...............................          .68%        .64%        .32%           .13%**
  Expenses, excluding distribution fee...............................          .55%        .51%        .19%           .00%**
  Net investment income..............................................         1.87%       2.02%       3.33%          4.48%**
</TABLE>
 
- ---------------
   * Commencement of investment operations.
  ** Annualized.
 (D) Net of management fee waiver and/or expense subsidy.
   # Total return includes reinvestment of dividends and distributions. Total 
     returns for periods of less than one year are not annualized.

See Notes to Financial Statements.
                                      -10-
 <PAGE>
<PAGE>
                          INDEPENDENT AUDITORS' REPORT

The Shareholders and Board of Trustees
Prudential Municipal Series Fund, New Jersey Money Market Series

   We have audited the accompanying statement of assets and liabilities of
Prudential Municipal Series Fund, New Jersey Money Market Series, including the
portfolio of investments, as of August 31, 1994, the related statements of
operations for the year then ended and of changes in net assets for each of the
two years in the period then ended, and the financial highlights for each of the
three years in the period then ended and for the period December 3, 1990
(commencement of investment operations) through August 31, 1991. These financial
statements and financial highlights are the responsibility of the Fund's
management. Our responsibility is to express an opinion on these financial
statements and financial highlights based on our audits.
   We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements and financial
highlights are free of material misstatement. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements. Our procedures included confirmation of the securities owned as of
August 31, 1994 by correspondence with the custodian. An audit also includes
assessing the accounting principles used and significant estimates made by
management, as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.
   In our opinion, such financial statements and financial highlights present
fairly, in all material respects, the financial position of Prudential Municipal
Series Fund, New Jersey Money Market Series, as stated August 31, 1994, the
results of its operations, the changes in its net assets, and its financial
highlights for the respective periods in conformity with generally accepted
accounting principles.

Deloitte & Touche LLP
New York, New York
October 17, 1994


                         FEDERAL INCOME TAX INFORMATION

   We are required by the Internal Revenue Code to advise you within 60 days of
the Series' fiscal year end (August 31, 1994) as to the federal tax status of
dividends paid by the Series during such fiscal year. Accordingly, we are
advising you that in the fiscal year ended August 31, 1994, dividends paid from
net investment income of $.02 per share were federally tax-exempt interest
dividends.
   In January 1995, you will be advised on IRS Form 1099 DIV or substitute 1099
DIV as to the federal tax status of the distributions received by you in
calendar year 1994.

                                      -11-












ANNUAL REPORT                                     August 31, 1994

Prudential
Municipal
Series Fund

(ICON)

New York Series

(LOGO)

<PAGE>
Letter to Shareholders

October 18, 1994

Dear Shareholder:It has been a most difficult year in the U.S. financial 
markets.  When we last wrote in February interest rates were starting to 
rise, ending a three-year long bull market in bonds. What started as a 
trickle has become a torrent.  Interest rates have continued to increase 
this year, sending bond prices down sharply.  Of course, as interest 
rates rise, bond prices decline.  In this environment of falling prices 
and unusual volatility, your Prudential Municipal Series Fund -- New York 
Series sought to minimize risk while maximizing your tax-free income.

The Series seeks maximum income exempt from New York City, New York 
State and federal income taxes* consistent with preservation of capital.  
The Series is comprised of investment grade municipal obligations with an 
average Aa/AA credit quality as determined by Moody's Investors Service 
or Standard & Poor's Ratings Group.  The Series performed in line with 
the Lipper New York Municipal Debt Average over the last year, but 
because long-term interest rates rose, total returns were disappointing.  
As a result, the Series has become more cautious and shortened its 
average maturity.

<TABLE>
                            SERIES PERFORMANCE 
                           As of August 31, 1994
<CAPTION>
                          30-day           Taxable Equivalent Yields  
                NAV      SEC Yield       @28%         @31%        @39.6%
<S>            <C>          <C>          <C>          <C>          <C>
Class A        $11.71       4.9%         7.4%         7.7%         8.8%
Class B        $11.71       4.7%         7.0%         7.3%         8.4% 
Class C        $11.71       N/A          N/A          N/A          N/A
</TABLE>

Investment return and principal value will fluctuate so that an 
investor's shares, when redeemed, may be worth more or less than 
their original cost.  Past performance is no guarantee of future 
results.

*Interest on municipal obligations may be subject to the federal 
alternative minimum tax. See your Series' prospectus for more details.

N/A = Yield information with respect to Class C is not available 
as operations commenced in August 1994.

                                 -1-

<PAGE>

<TABLE>
                            TOTAL RETURNS

                   Historical (As of 8/31/94)1    Average Annual (As of 9/30/94)2
<CAPTION>
                   1-Yr.  5-Yr.  Since Incep.**    1-Yr.  5-Yr.  Since Incep.**
<S>                <C>    <C>      <C>             <C>    <C>        <C>
Class A            -1.4%    N/A      +43.0%        -7.0%   N/A       +6.9%
Class B            -1.8%  +43.0%    +129.0%        -9.4%  +7.1%      +8.5%
Class C             N/A     N/A       +0.1%         N/A    N/A       -2.57%
Lipper NY
Muni Debt Avg.***  -1.4%  +45.9%    +147.8%         N/A    N/A         N/A  
</TABLE>

1 Source: Lipper Analytical Services, Inc. These figures do not take 
into account sales charges. 

2 Source: Prudential Mutual Fund Management, Inc.  These averages take 
into account applicable sales charges.  The Series charges a maximum 
initial sales charge of 3% for Class A shares.  Class B shares are 
subject to a declining contingent deferred sales charge of 5%, 4%, 
3%, 2%, 1% and 1%, respectively, for the first six years.  Class B 
shares will automatically convert to Class A shares approximately 
seven years after purchase.  This conversion feature is expected to 
be implemented in February 1995.  Class C shares are subject to a 
contingent deferred sales charge of 1% during the first year. 

**Inception on January 22, 1990 for Class A, September 13, 1984 for 
Class B and August 1, 1994 for Class C.

***These are the average returns of 70 New York municipal debt funds 
for one-year, five-year, and since inception of Class B shares, as 
determined by Lipper Analytical Services, Inc.

Once Was Not Enough

In February, the Federal Reserve raised short-term interest rates for 
the first time in years, hoping to control inflation.  Since then, the 
Fed has moved four more times, until the federal funds rate (the overnight 
interbank lending rate) now stands at 4.75%, up from 3% at the start of the 
year. The Fed also increased the discount rate (at which it lends banks 
money) to 4% from 3% over the same period.

Interest rates rise when the financial markets fear inflation, the bond 
holder's enemy. Inflation is feared because it robs purchasing power from 
a bond's fixed-interest rate.

Municipal bond interest rates increased by nearly a percentage point, to 
6.46% on August 25 from 5.52% on December 29, 1993, as measured by the 
Bond Buyer's Revenue Bond Index, a widely used yardstick of interest 
rates in the tax-free market.

New York:  Growing Slowly

New York's economy is growing modestly, but far slower than the rest 
of the nation.  Last year's payroll employment growth was only 0.9%, 
ranking it 45 of 50 states.

The state's economy remains diverse but it is becoming increasingly 
reliant on the financial services sector.  Any heavy dependance on a 
single sector makes an economy vulnerable.  In fact, layoffs in the 
financial services industry recently helped to drive up the state's 
unemployment rate to 7.1%.

                                 -2-

<PAGE>

Corporate restructuring is also restraining growth, as Pepsi, IBM, 
Kodak,  Xerox and some banks have announced consolidations.  In 
addition, health care reform is also driving consolidation in the 
insurance and health care sectors, which could lead to layoffs.  
And three large military bases are closing, resulting in the loss 
of 3,000 civilian jobs and 6,800 military personnel.

New York ended fiscal 1994 with a $1 billion surplus, which will be 
spent on tax relief to businesses and low income wage earners.  Since 
the state has a structural deficit of $1.2 billion, and is anticipating 
a very optimistic revenue growth of 7%, future challenges remain.  In 
fact, state union employees have not received raises for several years, 
so they will be pressuring the Legislature for action in the fiscal 1996 
budget.

We believe the state's credit is improving and have increased our exposure 
to state bonds backed by annual appropriations. We expect this sector to 
perform well.  Supply in New York is down 27.8% year-to-date compared 
with last year.

A Tax Reminder

As a result of the federal Revenue Reconciliation Act of 1993, which 
affects bonds purchased after April 30, 1993,  it is possible that 
this year you may have some taxable income from your tax-free municipal 
bond fund.  The law stipulates that the portion of any gain realized on 
the sale or retirement of a tax-free bond purchased at a market discount 
from its face value must be taxed as ordinary income.

As a result of this change in federal tax law, some discount bonds have 
been selling at levels so cheap they will produce a higher after-tax 
return than other bonds not subject to the provisions of the new law.  
We have occasionally taken advantage of this market imbalance because 
we have determined that at very low prices these bonds can still 
provide you with a higher after-tax return on your investment.

The Outlook

We expect volatility in the municipal bond market until the economy 
reaches a level of growth that is sustainable without causing inflation.  
If the economy continues to surge, the ever vigilant Fed will move again, 
boosting short-term rates.  If the economy slows substantially, long-term 
rates should stabilize.  Although rates may keep rising, we believe that 
most of the increase is now behind us.

In the months ahead, we expect supply -- or the lack of it -- to become 
more important in the tax-free municipal bond market.  Through the first 
eight months of the year, new issue volume is off 42%, according to 
Securities Data Co., which tracks this statistic.  The pace is 
accelerating.  In August, new issue volume fell 56%.  

                                 -3-

<PAGE>

As always, it is a pleasure to have you as a shareholder in the 
Prudential Municipal Series Fund -- New York Series, and to take 
this opportunity to report our activities to you.



Sincerely,

Lawrence C. McQuade 
President

Carla A. Wrocklage
Portfolio Manager


                                 -4-


<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                      Portfolio of Investments
NEW YORK SERIES                                                August 31, 1994

<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                  Value            
(Unaudited)     (000)          Description(a)         (Note 1)       
<C>           <C>          <S>                      <C>
                           LONG-TERM INVESTMENTS--97.3%
                           Babylon Ind. Dev. Agcy.
                             Res. Rec. Rev.,
                             Babylon Cmnty.
                             Waste Mgmt. Facs.,
Baa1           $  3,520(D) 7.875%, 7/1/06, Ser.
                             A....................  $  4,040,890
                           Ogden Martin Sys. Inc.,
Baa1                495    8.50%, 1/1/19, Ser.
                             B....................       540,718
Baa1              3,450    8.50%, 1/1/19, Ser.
                             C....................     3,768,642
                           Buffalo Swr. Auth. Sys.
                             Rev., F.G.I.C.,
Aaa               1,400    5.00%, 7/1/12, Ser.
                             G....................     1,222,830
                           City of New Rochelle
                             Ind. Dev. Agcy.,
                             Coll. of New
                             Rochelle,
BBB-*               500    6.625%, 7/1/12.........       508,785
BBB-*             2,000    6.75%, 7/1/22..........     2,035,660
                           Clifton Park Wtr.
                             Auth.,
                             Wtr. Sys. Rev.
Aaa               2,000    5.00%, 10/1/26,
                             F.G.I.C..............     1,662,560
                           Dutchess Cnty. Res.
                             Rec. Agcy. Rev.,
                             Solid Waste Mgmt.,
                             F.G.I.C.,
Aaa               1,150    7.50%, 1/1/09, Ser.
                             A....................     1,271,026
                           Great Neck No. Wtr.
                             Auth., Wtr. Sys.
                             Rev.,
A1                1,750(D) 7.00%, 1/1/18, Ser.
                             A....................     1,937,075
                           Guam Pwr. Auth. Rev.,
BBB*              1,750    6.30%, 10/1/22, Ser.
                             A....................     1,691,813
                           Islip Res. Rec.,
                             A.M.B.A.C.,
Aaa               1,745    7.20%, 7/1/10, Ser.
                             B....................     1,964,556
                           Jefferson Cnty. Ind.
                             Dev. Agcy. Solid
                             Waste Disp. Rev.,
Baa1              1,500    7.20%, 12/1/20.........     1,571,100
                           Metro. Trans. Auth.
                             Facs. Rev., Commuter
                             Facs.,
Baa1              1,000    5.75%, 7/1/13, Ser.
                             O....................       934,510
Baa1              5,000    6.00%, 7/1/21..........     4,744,550
                           Zero Coupon, 7/1/12,
                             Ser. N,
                             F.G.I.C..............     1,886,190
Aaa               5,575
                           Trans. Facs.,
Baa1              2,500    5.75%, 7/1/08, Ser.
                             O....................     2,403,000
Baa1              3,000    7.00%, 7/1/12, Ser.
                             5....................     3,154,740
Baa1              1,000    5.75%, 7/1/13, Ser.
                             O....................       934,510
                           Nassau Cnty. Ind. Dev.
                             Agcy. Rev., Hofstra
                             Univ. Proj.,
A              $  2,500(D) 8.25%, 7/1/03..........  $  2,810,525
                           Long Beach Proj.,
NR                1,420**  9.25%, 1/1/97..........       894,600
                           S&S Incinerator Jt.
                             Venture Proj.,
NR                2,785**  9.00%, 1/1/07..........     1,754,550
                           Nassau Cnty. Swr. Gen.
                             Oblig., F.G.I.C.,
                             Ser. B
Aaa               3,000    4.75%, 5/1/06..........     2,711,730
Aaa               3,845    4.80%, 5/1/07..........     3,445,620
                           New York City, Gen.
                             Oblig.,
Baa1              1,900    8.00%, 6/1/99, Ser.
                             B....................     2,123,668
Baa1              4,000    7.50%, 2/1/01, Ser.
                             B....................     4,395,640
Baa1              3,500    7.75%, 3/15/03, Ser.
                             A....................     3,880,275
Baa1              2,500    8.00%, 8/1/03, Ser.
                             D....................     2,853,200
Baa1              3,000    8.20%, 11/15/03, Ser.
                             F....................     3,452,340
Baa1              3,040    7.70%, 2/1/09, Ser.
                             D....................     3,365,250
Baa1              2,275    7.00%, 10/1/10, Ser.
                             B....................     2,388,864
                           New York City Ind. Dev.
                             Agcy.,
                             Spec. Fac. Rev.,
                             Term. One Group
                             Assoc. Proj.,
A                 5,000    6.00%, 1/1/15..........     4,773,750
                           Y.M.C.A. Of Greater
                             N.Y. Proj.,
NR                1,350    8.00%, 8/1/16..........     1,442,907
                           New York City Mun. Wtr.
                             Fin. Auth. Rev., Wtr.
                             & Swr. Sys.,
                           5.50%, 6/15/11, Ser. F,
                             A.M.B.A.C............     1,419,645
Aaa               1,500
Aaa               4,000(D)@ 7.375%, 6/15/13, Ser.
                             C....................     4,588,640
                           7.25%, 6/15/15, Ser. A,
Aaa               3,000    M.B.I.A................     3,388,530
                           5.75%, 6/15/20, Ser.F,
Aaa               3,250    M.B.I.A................     3,058,607
                           New York City Transit
                             Auth.,
                           5.40%, 1/1/18, Ser.
Aaa               7,900      1993, F.S.A..........     7,098,150
</TABLE>
 
                                      -5-     See Notes to Financial Statements.

<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                      
NEW YORK SERIES                                                
<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                  Value            
(Unaudited)     (000)          Description(a)         (Note 1)       
<C>           <C>          <S>                      <C>
                           New York St. Dorm.
                             Auth. Rev.,
                             City Univ. Sys.
                             Cons.,
Baa1           $  5,000    8.75%, 7/1/02, Ser.
                             D....................  $  6,040,000
Aaa               5,000(D)@ 8.00%, 7/1/07, Ser.
                             A....................     5,551,100
Baa1              3,435    8.125%, 7/1/07, Ser.
                             A....................     3,813,984
Baa1              1,880    7.00%, 7/1/09, Ser.
                             D....................     2,031,904
Aaa               3,500    7.50%, 7/1/10, Ser. C,
                             F.G.I.C..............     4,058,810
Baa1              2,000    5.75%, 7/1/18, Ser.
                             A....................     1,851,080
                           Coll. & Univ. Ed.,
                           Zero Coupon, 7/1/04,
                             M.B.I.A..............     1,320,054
Aaa               2,255
                           Columbia Univ.,
Aaa               4,750    4.75%, 7/1/14, Ser.
                             A....................     3,979,170
                           Dept. of Hlth.,
Baa1              2,000    5.50%, 7/1/20..........     1,757,820
                           Episcopal Hlth. Svcs.,
AAA*              4,500    7.55%, 8/1/29,
                             G.N.M.A..............     4,918,500
                           Fordham Univ.,
Aaa               4,000    5.50%, 7/1/23,
                             F.G.I.C..............     3,645,560
                           Long Island Med. Ctr.,
                             F.H.A.,
Aa                3,595    7.625%, 8/15/08, Ser.
                             A....................     3,934,763
Aa                4,100    7.75%, 8/15/27, Ser.
                             A....................     4,488,475
                           Menorah Campus,
AA*               3,000    7.40%, 2/1/31,
                             F.H.A................     3,296,010
                           Spec. Act Sch.
                             Districts,
Aaa               3,050    7.00%, 7/1/13,
                             F.G.I.C..............     3,281,739
                           St. Univ. Edl. Facs.,
Baa1                500    5.50%, 5/15/08, Ser.
                             A....................       471,025
Baa1              6,800    5.50%, 5/15/13, Ser.
                             A....................     6,199,356
                           5.25%, 5/15/15, Ser. A,
                             A.M.B.A.C............     1,974,412
Aaa               2,200
                           7.25%, 5/15/15, Ser. B,
                             F.G.I.C..............     2,829,700
Aaa               2,500
Aaa               1,770(D) 7.25%, 5/15/18, Ser.
                             A....................     2,025,252
                           Univ. of Rochester
                             Strong Mem. Hosp.,
A1                5,000    5.50%, 7/1/21..........     4,490,650
                           New York St. Energy
                             Resh. & Dev. Auth.
                             Rev.,
                             Brooklyn Union Gas
                             Co.,
A1             $  5,225    7.125%, 12/1/20, Ser.
                             1....................  $  5,531,864
Aaa               3,000    6.75%, 2/1/24,
                             M.B.I.A..............     3,125,310
Aaa               2,000(D)(D) 5.60%, 6/1/25,
                             M.B.I.A..............     1,785,780
                           7.914%, 7/8/26, Ser. D,
Aaa               2,000      M.B.I.A..............     1,645,000
                           Con. Edison Co.,
Aa3               6,735    7.50%, 7/1/25..........     7,200,254
Aa3               4,775    7.50%, 1/1/26..........     5,129,735
                           New York St. Environ.
                             Facs. Corp., Poll.
                             Ctrl. Rev.,
                             St. Wtr. Revolving
                             Fund,
Aa                5,000    7.25%, 6/15/10.........     5,460,400
Aa                1,300    7.50%, 3/15/11, Ser.
                             B....................     1,427,296
Aa                1,000    6.50%, 6/15/14, Ser.
                             E....................     1,025,070
                           New York St. Hsg. Fin.
                             Agcy. Rev.,
                             Multifamily Hsg.,
Aa                1,000    7.05%, 8/15/24, Ser.
                             A....................     1,027,270
                           St. Univ. Constr.,
Aaa               1,000(D) 8.10%, 11/1/10, Ser.
                             A....................     1,144,490
Aaa               3,600@   8.00%, 5/1/11, Ser.
                             A....................     4,368,672
                           Svc. Contract,
Aaa               2,000(D) 7.375%, 9/15/21, Ser.
                             A....................     2,311,860
                           New York St. Local
                             Gov't.
                             Assistance Corp.,
                             Ser. B
A                 2,000    5.625%, 4/1/13.........     1,869,840
A                 4,400    5.50%, 4/1/21..........     3,922,468
                           New York St. Med. Care
                             Facs. Fin. Agcy.
                             Rev.,
                             Booth Silvercrest &
                             Kings
                             Brook Hosp.,
Aa                2,750    7.60%, 2/15/29, Ser. A,
                             F.H.A................     3,016,255
                           Buffalo Gen. Hosp. &
                             Nursing Home,
AAA*              2,000(D) 7.60%, 2/15/08, Ser. C,
                             F.H.A................     2,241,900
                           Ellis & Ira Davenport
                             Hosp.,
Aa                1,495    8.00%, 2/15/28, Ser. B,
                             F.H.A................     1,651,990
</TABLE>
 
                                      -6-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                      
NEW YORK SERIES                                                

<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                  Value            
(Unaudited)     (000)          Description(a)         (Note 1)       
<C>           <C>          <S>                      <C>
                           New York St. Med. Care
                             Facs. Fin. Agcy.
                             Rev.,
                           Good Samaritian Hosp.,
                             F.H.A.,
Aa             $  3,500    7.625%, 2/15/23, Ser.
                             A....................  $  3,835,405
                           Hosp. & Nursing Home,
                             F.H.A.,
A*                2,180    8.625%, 2/15/06, Ser.
                             C....................     2,261,946
Aa                1,000(D) 7.70%, 2/15/25, Ser.
                             A....................     1,159,190
                           Long Island Coll.
                             Hosp., F.H.A.,
Aa                3,000    8.00%, 2/15/08, Ser.
                             B....................     3,301,620
AAA*              4,000    8.50%, 1/15/22, Ser.
                             A....................     4,308,920
                           Mental Hlth. Svcs.,
                             Ser. A,
Aaa               2,185(D) 7.50%, 8/15/07.........     2,500,558
Baa1                815    7.50%, 8/15/07.........       882,979
Aaa                 365(D) 7.75%, 8/15/11.........       423,553
Baa1                135    7.75%, 8/15/11.........       148,640
Aaa               3,135(D) 7.50%, 2/15/21.........     3,587,757
Baa1              1,165    7.50%, 2/15/21.........     1,269,326
                           St. Francis Hosp.,
                             F.G.I.C.,
Aaa               2,350    7.60%, 11/1/08, Proj.
                             A....................     2,616,208
                           New York St. Mtge.
                             Agcy. Rev.,
                             Homeowner Mtge.,
Aa                3,525    7.50%, 4/1/16, Ser.
                             EE2..................     3,748,732
Aa                1,620    6.875%, 4/1/17, Ser.
                             8A...................     1,650,634
Aa                3,145@   8.05%, 10/1/21.........     3,318,132
                           New York St. Mun. Bond
                             Bank Agcy., Spec.
                             Proj. Rev.,
A+*               3,000    6.75%, 3/15/11, Ser.
                             A....................     3,104,370
                           New York St. Pwr. Auth.
                             Rev. & Gen. Purp.,
Aa                2,000    6.75%, 1/1/18, Ser.
                             Y....................     2,090,360
Aa                1,000    6.25%, 1/1/23..........     1,001,280
                           New York St. Thrwy.
                             Auth. Gen. Rev.,
                           5.50%, 1/1/23,Ser. A,
                             F.G.I.C..............     1,451,216
Aaa               1,600
                           New York St. Urban Dev.
                             Corp.
                             Rev., Correctional
                             Cap. Facs.,
Baa1             10,000    Zero Coupon, 1/1/08....     4,345,100
Aaa               6,350    5.25%, 1/1/14,
                             F.S.A................     5,694,934
Baa1              2,960    5.25%, 1/1/21..........     2,486,341
                           Niagara Falls Bridge
                             Comn.,
Aaa            $  3,000(D) 6.125%, 10/1/19,
                             F.G.I.C..............  $  3,245,520
                           Toll Bridge Sys. Rev.,
Aaa               2,350    5.25%, 10/1/21,
                             F.G.I.C..............     2,039,354
                           Niagara Frontier Trans.
                             Auth. Arpt. Rev.,
                             Greater Buffalo Intl.
                             Arpt.,
Aaa               2,700    6.125%, 4/1/14,
                             A.M.B.A.C............     2,686,095
                           Oneida Herkimer Solid
                             Waste Mgmt. Auth.,
                             Solid Waste Sys.
                             Rev.,
Baa               3,000    6.75%, 4/1/14..........     3,031,380
                           Port Auth. of New York
                             & New Jersey,
A1                5,100    7.125%, 6/1/25, Ser.
                             69...................     5,588,019
A1                1,000    7.25%, 8/1/25, Ser.
                             70...................     1,085,070
A1                3,000    5.375%, 3/1/28.........     2,671,620
                           Puerto Rico Comnwlth.,
                             Gen. Oblig.,
Aaa               4,000    7.00%, 7/1/10,
                             A.M.B.A.C............     4,487,960
                           Pub. Impvt. Ref.,
Aaa               1,250    7.00%, 7/1/10..........     1,402,487
                           Puerto Rico Elec. Pwr.
                             Auth. Rev.,
Baa1              2,400    6.125%, 7/1/08, Ser.
                             S....................     2,480,184
                           Puerto Rico Hsg. Fin.
                             Auth. Rev.,
                             Multifamily Mtge.,
AA*               1,995    7.50%, 4/1/22..........     2,076,496
                           Puerto Rico Tel. Auth.
                             Rev.,
                           7.184%, 1/25/07, Ser.
Aaa               7,875@     I, M.B.I.A.,.........     7,382,812
                           Suffolk Cnty. Ind. Dev.
                             Agcy., Southwest Swr.
                             Sys. Rev., F.G.I.C.,
Aaa               1,000    6.00%, 2/1/07..........     1,024,580
Aaa               1,000    4.75%, 2/1/09..........       868,220
                           Suffolk Cnty. Wtr.
                             Auth.,
                             Waterworks Rev.,
Aaa               5,160    6.00%, 6/1/09,
                             M.B.I.A..............     5,245,346
Aaa                 250    5.00%, 6/1/17,
                             M.B.I.A..............       211,500
                           5.25%, 6/1/17, Ser. A,
Aaa               1,110(D) A.M.B.A.C..............     1,107,380
</TABLE>
 
                                      -7-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                      
NEW YORK SERIES                                                

<TABLE>
<CAPTION>
  Moody's     Principal
   Rating      Amount                                  Value
(Unaudited)     (000)          Description(a)         (Note 1)
<S>           <C>          <C>                       <C>
                           Triborough Bridge &
                             Tunl. Auth. Rev.,
Aaa            $  2,035(D) 7.50%, 1/1/15, Ser.
                             M....................  $  2,245,582
Aaa               2,500(D) 6.00%, 1/1/20, Ser.
                             R....................     2,617,950
                           Virgin Islands Pub.
                             Fin. Auth. Rev.,
                             Hwy. Trans. Trust
                             Fund,
BBB*              2,500    7.70%, 10/1/04.........     2,732,175
NR                2,550    7.25%, 10/1/18, Ser.
                             A....................     2,630,631
                           Virgin Islands Wtr. &
                             Pwr. Auth.,
                             Elec. Sys.,
NR                2,300    8.50%, 1/1/10, Ser.
                             A....................     2,526,688
                                                    ------------
                           Total long-term
                             investments
                             (cost
                             $322,325,026)........   336,538,714
                                                    ------------
                           SHORT-TERM INVESTMENTS--1.6%
                           New York City Gen.
                             Oblig.,
VMIG1             3,100    3.20%, 9/1/94, Ser. A,
                             F.R.D.D..............     3,100,000
                           New York City Ind. Dev.
                             Agcy., Spec. Fac.
                             Rev.,
                             Japan Airlines,
                             F.R.D.D.,
A1*               2,500    3.30%, 9/1/94, Ser.
                             91...................     2,500,000
                                                    ------------
                           Total short-term
                             investments
                             (cost $5,600,000)....     5,600,000
                                                    ------------
                           Total Investments--98.9%
                           (cost $327,925,026;
                             Note 4)..............  $342,138,714
                           Other assets in excess
                             of
                             liabilities--1.1%....     3,645,978
                                                    ------------
                           Net Assets--100%.......  $345,784,692
                                                    ------------
                                                    ------------
</TABLE>
 
- ---------------
(a) The following abbreviations are used in portfolio descriptions:
    A.M.B.A.C.--American Municipal Bond Assurance Corporation.
    F.G.I.C.--Financial Guaranty Insurance Company.
    F.H.A.--Federal Housing Administration.
    F.R.D.D.--Floating Rate (Daily) Demand Note #.
    F.S.A.--Financial Security Assurance.
  G.N.M.A.--Government National Mortgage Association.
    M.B.I.A.--Municipal Bond Insurance Association.

          # For purposes of amortized cost valuation, the
            maturity date of this security is considered to
            be the later of the next date on which the
            security can be redeemed at par or the next date
            on which the rate of interest is adjusted.
          * Standard & Poor's rating.
         ** Issuer in default, non-income producing
            security.
          @ Pledged as initial margin on financial futures
            contracts.
        (D) Prerefunded issues are secured by escrowed cash
            and/or direct U.S. guaranteed obligations.
     (D)(D) Inverse floating rate bond. The coupon is
            inversely indexed to a floating interest rate.
            The rate shown is the rate at period end.
 
NR--Not Rated by Moody's or Standard & Poor's.
The Fund's current Statement of Additional Information contains a description of
Moody's and Standard & Poor's ratings.
                                      -8-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW YORK SERIES
 Statement of Assets and Liabilities
<TABLE>
<CAPTION>
Assets                                                                                      August 31, 1994
                                                                                            ---------------
<S>                                                                                         <C>
Investments, at value (cost $327,925,026)................................................    $ 342,138,714
Cash.....................................................................................          248,699
Interest receivable......................................................................        4,469,823
Receivable for Series shares sold........................................................          263,716
Deferred expenses and other assets.......................................................           10,467
                                                                                            ---------------
    Total assets.........................................................................      347,131,419
                                                                                            ---------------
Liabilities
Payable for Series shares reacquired.....................................................          625,138
Dividends payable........................................................................          289,151
Management fee payable...................................................................          146,728
Distribution fee payable.................................................................          142,156
Due to broker - variation margin.........................................................           14,562
Deferred trustees' fees..................................................................            1,010
Accrued expenses.........................................................................          127,982
                                                                                            ---------------
Total liabilities........................................................................        1,346,727
                                                                                            ---------------
Net Assets...............................................................................    $ 345,784,692
                                                                                            ---------------
                                                                                            ---------------
Net assets were comprised of:
  Shares of beneficial interest, at par..................................................    $     295,236
  Paid-in capital in excess of par.......................................................      331,843,528
                                                                                            ---------------
                                                                                               332,138,764
  Accumulated net realized loss on investments...........................................         (572,604)
  Net unrealized appreciation on investments.............................................       14,218,532
                                                                                            ---------------
  Net assets, August 31, 1994............................................................    $ 345,784,692
                                                                                            ---------------
                                                                                            ---------------
Class A:
  Net asset value and redemption price per share
    ($13,660,690 / 1,166,759 shares of beneficial interest issued and outstanding).......           $11.71
  Maximum sales charge (3.0% of offering price)..........................................              .36
                                                                                            ---------------
  Maximum offering price to public.......................................................           $12.07
                                                                                            ---------------
                                                                                            ---------------
Class B:
  Net asset value, offering price and redemption price per share
    ($331,981,953 / 28,344,685 shares of beneficial interest issued and outstanding).....           $11.71
                                                                                            ---------------
                                                                                            ---------------
Class C:
  Net asset value, offering price and redemption price per share
    ($142,049 / 12,129 shares of beneficial interest issued and outstanding).............           $11.71
                                                                                            ---------------
                                                                                            ---------------
</TABLE>
 
See Notes to Financial Statements.
                                      -9-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW YORK SERIES
 Statement of Operations
<TABLE>
<CAPTION>
                                         Year Ended
                                         August 31,
Net Investment Income                       1994
                                        ------------
<S>                                     <C>
Income
  Interest............................  $ 22,542,861
                                        ------------
Expenses
  Management fee......................     1,820,106
  Distribution fee--Class A...........        13,454
  Distribution fee--Class B...........     1,752,818
  Distribution fee--Class C...........            25
  Transfer agent's fees and
  expenses............................       200,000
  Custodian's fees and expenses.......       130,000
  Reports to shareholders.............        90,000
  Registration fees...................        35,000
  Legal fees..........................        15,000
  Audit fee...........................        10,500
  Insurance expense...................         7,000
  Trustees' fees......................         3,375
  Miscellaneous.......................        11,002
                                        ------------
    Total expenses....................     4,088,280
                                        ------------
Net investment income.................    18,454,581
                                        ------------
Realized and Unrealized
Gain (Loss) on Investments
Net realized gain (loss) on:
  Investment transactions.............        41,440
  Financial futures transactions......       (57,494)
                                        ------------
                                             (16,054)
                                        ------------
Net change in unrealized
  appreciation/depreciation on:
  Investments.........................   (25,216,409)
  Financial futures contracts.........         4,844
                                        ------------
                                         (25,211,565)
                                        ------------
Net loss on investments...............   (25,227,619)
                                        ------------
Net Decrease in Net Assets
Resulting from Operations.............  $ (6,773,038)
                                        ------------
                                        ------------
</TABLE>
 
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW YORK SERIES
 Statement of Changes in Net Assets
<TABLE>
<CAPTION>
                              Year Ended August 31,
Increase (Decrease)        ----------------------------
in Net Assets                  1994            1993
                           ------------    ------------
<S>                        <C>             <C>
Operations
  Net investment
    income...............  $ 18,454,581    $ 18,305,266
  Net realized gain
    (loss) on investment
    transactions.........       (16,054)      8,650,226
  Net change in
    unrealized
appreciation/depreciation
    of investments.......   (25,211,565)     13,853,347
                           ------------    ------------
  Net increase (decrease)
    in net assets
    resulting from
    operations...........    (6,773,038)     40,808,839
                           ------------    ------------
Dividends from net
  investment income (Note
  1)
    Class A..............      (734,832)       (504,683)
    Class B..............   (17,719,575)    (17,800,583)
    Class C..............          (174)             --
                           ------------    ------------
                            (18,454,581)    (18,305,266)
                           ------------    ------------
Series share transactions
  (Note 5)
  Net proceeds from
    shares sold..........    41,684,512      56,310,026
  Net asset value of
    shares issued in
    reinvestment of
    dividends............    11,015,273      10,865,791
  Cost of shares
  reacquired.............   (52,115,672)    (41,780,067)
                           ------------    ------------
  Net increase in net
    assets from Series
    share transactions...       584,113      25,395,750
                           ------------    ------------
Total increase
  (decrease).............   (24,643,506)     47,899,323
Net Assets
Beginning of year........   370,428,198     322,528,875
                           ------------    ------------
End of year..............  $345,784,692    $370,428,198
                           ------------    ------------
                           ------------    ------------
</TABLE>
 
See Notes to Financial Statements.        See Notes to Financial Statements.
                                      -10-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW YORK SERIES
 Notes to Financial Statements
   Prudential Municipal Series Fund (the ``Fund'') is registered under the
Investment Company Act of 1940 as an open-end investment company. The Fund was
organized as a Massachusetts business trust on May 18, 1984 and consists of
seventeen series. The monies of each series are invested in separate,
independently managed portfolios. The New York Series (the ``Series'') commenced
investment operations in September, 1984. The Series is diversified and seeks to
achieve its investment objective of obtaining the maximum amount of income
exempt from federal and applicable state and city income taxes with the minimum
of risk by investing in ``investment grade'' tax-exempt securities and whose
ratings are within the four highest ratings categories by a nationally
recognized statistical rating organization or, if not rated, are of comparable
quality. The ability of the issuers of the securities held by the Series to meet
their obligations may be affected by economic developments in a specific state,
industry or region.
                              
Note 1. Accounting            The following is a summary
Policies                      of significant accounting poli-
                              cies followed by the Fund, and the Series, in the
preparation of its financial statements.
Securities Valuations: The Series values municipal securities (including
commitments to purchase such securities on a ``when-issued'' basis) on the basis
of prices provided by a pricing service which uses information with respect to
transactions in bonds, quotations from bond dealers, market transactions in
comparable securities and various relationships between securities in
determining values. If market quotations are not readily available from such
pricing service, a security is valued at its fair value as determined under
procedures established by the Trustees.
   Short-term securities which mature in more than 60 days are valued at current
market quotations. Short-term securities which mature in 60 days or less are
valued at amortized cost.
   All securities are valued as of 4:15 P.M., New York time.
Financial Futures Contracts: A financial futures contract is an agreement to
purchase (long) or sell (short) an agreed amount of debt securities at a set
price for delivery on a future date. Upon entering into a financial futures
contract, the Series is required to pledge to the broker an amount of cash
and/or other assets equal to a certain percentage of the contract amount. This
amount is known as the ``initial margin''. Subsequent payments, known as
``variation margin'', are made or received by the Series each day, depending on
the daily fluctuations in the value of the underlying security. Such variation
margin is recorded for financial statement purposes on a daily basis as
unrealized gain or loss.
   The Series invests in financial futures contracts solely for the purpose of
hedging its existing portfolio securities or securities the Series intends to
purchase against fluctuations in value caused by changes in prevailing market
interest rates. Should interest rates move unexpectedly, the Series may not
achieve the anticipated benefits of the financial futures contracts and may
realize a loss. The use of futures transactions involves the risk of imperfect
correlation in movements in the price of futures contracts, interest rates and
the underlying hedged assets.
Securities Transactions and Investment Income: Securities transactions are
recorded on the trade date. Realized gains and losses on sales of securities are
calculated on the identified cost basis. Interest income is recorded on the
accrual basis. The Series amortizes premiums and original issue discount paid on
purchases of portfolio securities as adjustments to interest income.
   Net investment income (other than distribution fees), and unrealized and
realized gains or losses are allocated daily to each class of shares based upon
the relative proportion of net assets of each class at the beginning of the day.
Federal Income Taxes: For federal income tax purposes, each series in the Fund
is treated as a separate taxpaying entity. It is the intent of the Series to
continue to meet the requirements of the Internal Revenue Code applicable to
regulated investment companies and to distribute all of its net income to
shareholders. For this reason and because substantially all of the Series' gross
income consists of tax-exempt interest, no federal income tax provision is
required.
Dividends and Distributions: The Series declares daily dividends from net
investment income. Payment of dividends is made monthly. Distributions of net
capital gains, if any, are made annually.
   Income distributions and capital gain distributions are determined in
accordance with income tax regulations which may differ from generally accepted
accounting principles.
                              
Note 2. Agreements            The Fund has a management
                              agreement with Prudential Mutual Fund Management,
Inc. (``PMF''). Pursuant to this
                                      -11-
 <PAGE>
<PAGE>
agreement, PMF has responsibility for all investment advisory services and
supervises the subadviser's performance of such services. PMF has entered into a
subadvisory agreement with The Prudential Investment Corporation (``PIC''); PIC
furnishes investment advisory services in connection with the management of the
Fund. PMF pays for the cost of the subadviser's services, the compensation of
officers of the Fund, occupancy and certain clerical and bookkeeping costs of
the Fund. The Fund bears all other costs and expenses.
   The management fee paid PMF is computed daily and payable monthly, at an
annual rate of .50 of 1% of the average daily net assets of the Series.
   The Fund has distribution agreements with Prudential Mutual Fund
Distributors, Inc. (``PMFD''), which acts as the distributor of the Class A
shares of the Fund, and with Prudential Securities Incorporated (``PSI''), which
acts as distributor of the Class B and Class C shares of the Fund (collectively
the ``Distributors''). The Fund compensates the Distributors for distributing
and servicing the Fund's Class A, Class B and Class C shares, pursuant to plans
of distribution, (the ``Class A, B and C Plans'') regardless of expenses
actually incurred by them. The distribution fees are accrued daily and payable
monthly.
   On July 19, 1994, shareholders of the Fund approved amendments to the Class A
and Class B distribution plans under which the distribution plans became
compensation plans, effective August 1, 1994. Prior thereto, the distribution
plans were reimbursement plans, under which PMFD and PSI were reimbursed for
expenses actually incurred by them up to the amount permitted under the Class A
and Class B Plans, respectively. The Fund is not obligated to pay any prior or
future excess distribution costs (costs incurred by the Distributors in excess
of distribution fees paid by the Fund or contingent deferred sales charges
received by the Distributors). The rate of the distribution fees charged to
Class A and Class B shares of the Fund did not change under the amended plans of
distribution. The Fund began offering Class C shares on August 1, 1994.
   Pursuant to the Class A, B and C Plans, the Fund compensates the Distributors
for distribution-related activities at an annual rate of up to .30 of 1%, .50 of
1% and 1%, of the average daily net assets of the Class A, B and C shares,
respectively. Such expenses under the Plans were .10 of 1%, .50 of 1% and .75 of
1% of the average daily net assets of the Class A, B and C shares, respectively,
for the fiscal year ended August 31, 1994.
   PMFD has advised the Series that it has received approximately $166,000 in
front-end sales charges resulting from sales of Class A shares during the fiscal
year ended August 31, 1994. From these fees, PMFD paid such sales charges to PSI
and Pruco Securities Corporation, affiliated broker-dealers, which in turn paid
commissions to salespersons and incurred other distribution costs.
   PSI has advised the Series that for the fiscal year ended August 31, 1994, it
received approximately $336,000 in contingent deferred sales charges imposed
upon certain redemptions by Class B and Class C shareholders.
   PMFD is a wholly-owned subsidiary of PMF; PSI, PMF and PIC are indirect,
wholly-owned subsidiaries of The Prudential Insurance Company of America.
                              
Note 3. Other                 Prudential Mutual Fund Ser-
Transactions                  vices, Inc. (``PMFS''), a 
with Affiliates               wholly-owned subsidiary of 
                              PMF, serves as the Fund's transfer agent. During
the year ended August 31, 1994, the Series incurred fees of approximately
$138,000 for the services of PMFS. As of August 31, 1994, approximately $11,000
of such fees were due to PMFS. Transfer agent fees and expenses in the Statement
of Operations include certain out-of-pocket expenses paid to non-affiliates.
                              
Note 4. Portfolio             Purchases and sales of port-
Securities                    folio securities of the Series, 
                              excluding short-term investments, for the year
ended August 31, 1994 were $173,466,474 and $171,186,994, respectively.
   The cost basis of investments for federal income tax purposes at August 31,
1994 was $327,953,225 and, accordingly, net unrealized appreciation of
investments for federal income tax purposes was $14,185,489 (gross unrealized
appreciation--$20,970,868, gross unrealized depreciation--$6,785,379).
   For federal income tax purposes, the Series had a capital loss carryforward
as of August 31, 1994 of approximately $15,700 which expires in 1999. Such
carryforward is after utilization of approximately $512,600 to offset the
Series' net taxable gains recognized in the year ended August 31, 1994.
Accordingly, no capital gains distributions are expected to be paid to
shareholders until net gains have been realized in excess of such carryforward.
   The Series will elect to treat net capital losses of approximately $531,600
incurred in the ten month period ended August 31, 1994 as having been incurred
in the following fiscal year.
   At August 31, 1994, the Series sold 2 financial futures contracts on the U.S.
Treasury Bond Index expiring in September 1994 and December 1994, respectively.
The value at disposition of such contracts is $4,187,031. The value of
                                      -12-
 <PAGE>
<PAGE>
such contracts on August 31, 1994 was $4,182,187, thereby resulting in an
unrealized gain of $4,844.
                              
Note 5. Capital               The Series currently offers
                              Class A, Class B and Class C shares. Class A
shares are sold with a front-end sales charge of up to 3.0%. Class B shares are
sold with a contingent deferred sales charge which declines from 5% to zero
depending on the period of time the shares are held. Class C shares are sold
with a contingent deferred sales charge of 1% during the first year. Class B
shares will automatically convert to Class A shares on a quarterly basis
approximately seven years after purchase commencing in or about February, 1995.
   The Fund has authorized an unlimited number of shares of beneficial interest
of each class at $.01 par value per share.
   Transactions in shares of beneficial interest for the years ended August 31,
1994 and 1993 were as follows:
<TABLE>
<CAPTION>
Class A                           Shares         Amount
<S>                             <C>           <C>
                                ----------    ------------
Year ended August 31, 1994:
Shares sold..................      568,443    $  6,979,928
Shares issued in reinvestment
  of
  dividends..................       34,634         419,800
Shares reacquired............     (379,015)     (4,536,278)
                                ----------    ------------
Net increase in shares
  outstanding................      224,062    $  2,863,450
                                ----------    ------------
                                ----------    ------------
Year ended August 31, 1993:
Shares sold..................      629,556    $  7,599,542
Shares issued in reinvestment
  of
  dividends..................       25,616         309,097
Shares reacquired............     (227,933)     (2,765,199)
                                ----------    ------------
Net increase in shares
  outstanding................      427,239    $  5,143,440
                                ----------    ------------
                                ----------    ------------
</TABLE>
<TABLE>
<CAPTION>
Class B                            Shares         Amount
<S>                              <C>           <C>
                                 ----------    ------------
Year ended August 31, 1994:
Shares sold...................    2,819,758    $ 34,553,962
Shares issued in reinvestment
  of
  dividends...................      873,809      10,595,424
Shares reacquired.............   (3,939,794)    (47,570,423)
                                 ----------    ------------
Net decrease in shares
  outstanding.................     (246,227)   $ (2,421,037)
                                 ----------    ------------
                                 ----------    ------------
Year ended August 31, 1993:
Shares sold...................    4,042,874    $ 48,710,484
Shares issued in reinvestment
  of
  dividends...................      877,265      10,556,694
Shares reacquired.............   (3,254,011)    (39,014,868)
                                 ----------    ------------
Net increase in shares
  outstanding.................    1,666,128    $ 20,252,310
                                 ----------    ------------
                                 ----------    ------------
 
<CAPTION>
Class C
<S>                              <C>           <C>
August 1, 1994* through
  August 31, 1994:
Shares sold...................       12,897    $    150,622
Shares issued in reinvestment
  of
  dividends...................            4              49
Shares reacquired.............         (772)         (8,971)
                                 ----------    ------------
Net increase in shares
  outstanding.................       12,129    $    141,700
                                 ----------    ------------
                                 ----------    ------------
- ---------------
* Commencement of offering of Class C shares.
</TABLE>
                                      -13-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW YORK SERIES
 Financial Highlights
<TABLE>
<CAPTION>
                                Class A                                               Class B                           Class C
           --------------------------------------------------   ----------------------------------------------------   ----------
<S>        <C>       <C>       <C>      <C>      <C>            <C>        <C>        <C>        <C>        <C>        <C>
                                                 January 22,                                                           August 1,
                                                   1990(D)                                                             1994(D)(D)
                  Year Ended August 31,            Through                     Year Ended August 31,                    Through
           -----------------------------------    August 31,    ----------------------------------------------------   August 31,
            1994      1993      1992     1991        1990         1994       1993       1992       1991       1990        1994
           -------   -------   ------   ------   ------------   --------   --------   --------   --------   --------   ----------
PER SHARE
OPERATING
  PERFORMANCE:
Net asset
  value,
beginning
  of
period...   $12.54   $ 11.75   $11.08   $10.62      $10.81      $  12.54   $  11.75   $  11.08   $  10.62   $  10.88     $11.74
           -------   -------   ------   ------      ------      --------   --------   --------   --------   --------   ----------
Income
  from
  investment
  operations
Net
investment
 income...     .67       .70      .71      .72         .42           .62        .65        .66        .67        .65        .04
Net
 realized
  and
  unrealized
  gain
  (loss)
  on
  investment
  trans-
  actions...  (.83)      .79    .67        .46        (.19)         (.83)       .79        .67        .46       (.26)      (.03)
           -------   -------   ------   ------      ------      --------   --------   --------   --------   --------   ----------
  Total
    from
    investment
    oper-
    ations... (.16)     1.49   1.38       1.18         .23          (.21)      1.44       1.33       1.13        .39        .01
Less
dividends
Dividends
  from
  net
  investment
income...     (.67)     (.70)    (.71)    (.72)       (.42)         (.62)      (.65)      (.66)      (.67)      (.65)      (.04)
           -------   -------   ------   ------      ------      --------   --------   --------   --------   --------   ----------
Net asset
  value,
  end of
period...  $ 11.71   $ 12.54   $11.75   $11.08      $10.62      $  11.71   $  12.54   $  11.75   $  11.08   $  10.62     $11.71
           -------   -------   ------   ------      ------      --------   --------   --------   --------   --------   ----------
           -------   -------   ------   ------      ------      --------   --------   --------   --------   --------   ----------
TOTAL
RETURN#:...  (1.38)%   13.06%   12.73%   11.49%       2.03%        (1.77)%    12.61%     12.32%     10.96%      3.73%      0.06%
RATIOS/SUPPLEMENTAL
  DATA:
Net
  assets,
  end of
  period
 (000)...  $13,661   $11,821   $6,057   $2,729      $1,174      $331,982   $358,607   $316,472   $293,942   $313,606     $  142
Average
  net
  assets
 (000)...  $13,454   $ 8,755   $4,024   $1,579      $  588      $350,564   $330,823   $303,016   $295,285   $332,580     $   42
Ratios to
  average
  net
assets:##
Expenses,
including
    distribution
    fees...    .74%    .74%       .74%     .71%        .78%*        1.14%      1.14%      1.14%      1.11%      1.17%      1.62%*
Expenses,
excluding
    distribution
    fees...    .64%    .64%       .64%     .61%        .68%*         .64%       .64%       .64%       .61%       .67%       .87%*
  Net
  investment
  income...   5.46%   5.78%      6.19%    6.61%       6.41%*        5.06%      5.38%      5.79%      6.21%      6.10%      5.17%*
Portfolio
turnover...     49%     44%        45%      78%        127%           49%        44%        45%        78%       127%        49%

 
- ---------------
   * Annualized.
 (D) Commencement of offering of Class A shares.
(D)(D) Commencement of offering of Class C shares.
   # Total return does not consider the effects of sales loads. Total return is calculated assuming a purchase
     of shares on the first day and a sale on the last day of each period reported and includes reinvestment of
     dividends. Total returns for periods of less than a full year are not annualized.
  ## Because of the events referred to in (D)(D) and the timing of such, the ratios for the Class C shares are
     not necessarily comparable to that of Class A or B shares and are not necessarily indicative of future
     ratios.
</TABLE>

See Notes to Financial Statements.
                                      -14-
 <PAGE>
<PAGE>
                          INDEPENDENT AUDITORS' REPORT
The Shareholders and Board of Trustees
Prudential Municipal Series Fund, New York Series
   We have audited the accompanying statement of assets and liabilities of
Prudential Municipal Series Fund, New York Series, including the portfolio of
investments, as of August 31, 1994, the related statements of operations for the
year then ended and of changes in net assets for each of the two years in the
period then ended, and the financial highlights for each of the five years in
the period then ended. These financial statements and financial highlights are
the responsibility of the Fund's management. Our responsibility is to express an
opinion on these financial statements and financial highlights based on our
audits.
   We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements and financial
highlights are free of material misstatement. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements. Our procedures included confirmation of the securities owned as of
August 31, 1994 by correspondence with the custodian. An audit also includes
assessing the accounting principles used and significant estimates made by
management, as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.
   In our opinion, such financial statements and financial highlights present
fairly, in all material respects, the financial position of Prudential Municipal
Series Fund, New York Series, as of August 31, 1994, the results of its
operations, the changes in its net assets, and its financial highlights for the
respective stated periods in conformity with generally accepted accounting
principles.
Deloitte & Touche LLP
New York, New York
October 17, 1994
                         FEDERAL INCOME TAX INFORMATION
   We are required by the Internal Revenue Code to advise you within 60 days of
the Series' fiscal year end (August 31, 1994) as to the federal tax status of
dividends paid by the Series during such fiscal year. Accordingly, we are
advising you that in the fiscal year ended August 31, 1994, dividends paid from
net investment income of $.67 per share for Class A shares, $.62 per Class B
shares and $.04 per Class C shares were all federally tax-exempt interest
dividends.
   In January 1995, you will be advised on IRS Form 1099 DIV or substitute 1099
DIV as to the federal tax status of the dividends received by you in calendar
year 1994.
                                      -15-
 <PAGE>
<PAGE>
   These graphs are furnished to you in accordance with SEC regulations. They
compare a $10,000 investment in Prudential Municipal Series Fund: New York
Series (Class A, Class B, and Class C) with a similar investment in the Lehman
Brothers Municipal Bond Index (the Index) by portraying the initial account
values at the commencement of operations of each class and subsequent account
values at the end of each fiscal year (August 31) beginning in 1990 for Class A,
in 1985 for Class B shares and 1994 for Class C shares. For purposes of the
graphs and, unless otherwise indicated, the accompanying tables, it has been
assumed that
(a) the maximum sales charge was deducted from the initial $10,000 investment in
Class A shares; (b) the maximum applicable contingent deferred sales charge was
deducted from the value of the investment in Class B shares and Class C shares,
assuming full redemption on August 31, 1994; (c) all recurring fees (including
management fees) were deducted; and (d) all dividends and distributions were
reinvested. Class B shares will automatically convert to Class A shares on a
quarterly basis approximately seven years after purchase. This conversion
feature is expected to be implemented on or about February 1995 and is not
reflected in the graph. The graph and accompanying tables reflect the past
subsidy and/or waiver of expenses and/or management fees. Without fee waivers
and expense subsidies, the value of a $10,000 investment in the Series and the
Series' average annual total return, as shown above, would have been lower.
   The Index is a weighted index comprised of 21,000 municipal bonds (general
obligation bonds, revenue bonds, insured bonds and prerefunded bonds) selected
by Lehman Brothers as representative of the long-term investment grade municipal
bond market. The Index is an unmanaged index and includes the reinvestment of
all income, but does not reflect the payment of transaction costs and advisory
fees associated with an investment in the Series. The securities which comprise
the Index may differ substantially from the securities in the Series' portfolio
because the Index, among other things, is not state specific. The Lehman
Brothers Municipal Bond Index is not the only index which may be used to
characterize performance of long-term, investment-grade tax-exempt bond funds
and other indexes may portray different comparative performance.
                                      -16-
 <PAGE>
<PAGE>

Trustees
Edward D. Beach
Eugene C. Dorsey
Delayne Dedrick Gold
Harry A. Jacobs, Jr.
Lawrence C. McQuade
Thomas T. Mooney
Thomas H. O'Brien
Richard A. Redeker
Nancy H. Teeters

Officers
Lawrence C. McQuade, President
Robert F. Gunia, Vice President
Susan C. Cote, Treasurer
S. Jane Rose, Secretary
Ronald Amblard, Assistant Secretary
Deborah A. Docs, Assistant Secretary

Manager
Prudential Mutual Fund Management, Inc.
One Seaport Plaza
New York, NY 10292

Investment Adviser
The Prudential Investment Corporation
Prudential Plaza
Newark, NJ 07101

Distributors
Prudential Mutual Fund Distributors, Inc.
Prudential Securities Incorporated
One Seaport Plaza
New York, NY 10292

Custodian
State Street Bank and Trust Company
One Heritage Drive
North Quincy, MA 02171

Transfer Agent
Prudential Mutual Fund Services, Inc.
P.O. Box 15005
New Brunswick, NJ 08906

Independent Accountants
Deloitte & Touche LLP
1633 Broadway
New York, NY 10019

Legal Counsel
Gardner, Carton & Douglas
Quaker Tower
321 North Clark Street
Chicago, IL 60610-4795

Prudential Mutual Funds
One Seaport Plaza
New York, NY 10292
Toll free (800) 225-1852, Collect (908) 417-7555

This report is not authorized for distribution to prospective 
investors unless preceded or accompanied by a current prospectus.

74435M747  
74435M754                            MF 122E
74435M523          (LOGO)      Cat. #6423319


























































ANNUAL REPORT                                       August 31, 1994


Prudential
Municipal
Series Fund

(ICON)

New York
Money Market Series

(LOGO)

<PAGE>
Letter to Shareholders

October 18, 1994 

Dear Shareholder:

Short-term interest rates moved steadily higher during the last 12 
months, accelerating in 1994 as the Federal Reserve boosted short-term 
interest rates in hopes of preventing inflation from increasing as 
the economy began to expand rapidly.  As a result, your Prudential 
Municipal Series Fund -- New York Money Market Series -- produced 
higher yields than six months ago. 

<TABLE>
                      SERIES PERFORMANCE 1
                      As of August 31, 1994
<CAPTION>
Net Asset  Weighted       7-Day        Taxable Equivalent Yield       Net
 Value2    Avg. Mat.  Current Yield    @28%     @31%     @39.6%   Asset (Mil.)
<S>         <C>          <C>           <C>      <C>      <C>        <C>
$1.00       43 days      2.24%         3.4%     3.5%     4.0%       $269.1
</TABLE>

1Past performance is no guarantee of future results.

2Please note than an investment in the Series is neither insured 
nor guaranteed by the  U. S. government, and there can be no assurance 
that the Series will be able to maintain a stable net asset value of 
$1.00 per share.

The New York Money Market Series seeks to maximize current income that 
is exempt from New York State, New York City and federal income taxes 
with the preservation of principal and liquidity.  Interest on municipal 
obligations may be subject to the federal alternative minimum tax.  The 
Series invests primarily in high-quality, short-term, tax-exempt 
obligations issued by the state, municipalities and authorities.  
During the year, the Series' credit quality remained consistently 
high, with 98% of  its holdings rated in the highest category, as 
determined by Moody's Investor's Service or Standard & Poor's, or 
if unrated, deemed to be of comparable quality by the adviser.

In 1994, Rates Rose Rapidly

Short-term taxable interest rates were relatively stable until February, 
when the Federal Reserve, concerned that the rapidly expanding economy 
could ignite inflation, started to increase the fed funds rate (the 
overnight interbank lending rate).  If the economy grows too quickly, 
shortages develop and consumers and businesses bid up the prices of 
materials and labor.

The Municipal Market Is Different

While the fed funds rate spiked 175 basis points (100 basis points is 
one percentage point), the yields of tax-free securities did not increase 
by a similar margin.  Although this rising interest rate activity in the 
taxable market 

                              -1-

<PAGE>

does affect the tax-free market, the impact generally 
lags.  The short-term municipal market is also more influenced by 
seasonal supply and demand factors than  taxable Treasury bills.

Rising rates in the taxable market can be followed by higher yields 
in the tax-free market.  Anticipating the Fed would raise interest 
rates in February, we maintained a shorter weighted average maturity 
so that we could take advantage of higher rates as they became available.  
Once the Fed moved, we selectively extended the maturity of the portfolio.  
Generally, our weighted average maturity was shorter than that of our peers. 

New York: Growing Modestly

New York's economy is growing modestly, but still slower than the rest of 
the nation. Last year's payroll employment growth was only 0.9%, ranking 
it 45 out of 50 states.

The state's economy remains diverse and substantial, but it is becoming 
increasingly dependent on the financial services sector.  Dominance by 
any single sector makes an economy vulnerable.  In fact, layoffs in the 
financial services industry recently helped to drive up the state's 
unemployment rate to 7.1%.

Corporate restructuring is also restraining growth, as Pepsi, IBM, 
Kodak,  Xerox and some banks have announced consolidations.  In 
addition, health care reform is also driving cutbacks in the insurance 
and health care sectors.  And three large military bases are closing, 
resulting in the loss of 3,000 civilian jobs and 6,800 military personnel.

New York ended fiscal 1994 with a $1 billion surplus,  which will be 
spent on tax relief to businesses and low income wage earners.  Since 
the state has a structural deficit of $1.2 billion, and is anticipating 
a very optimistic revenue growth of 7%, future challenges remain.  In 
fact, state union employees have not received raises for several years, 
so they will be pressuring the Legislature for action in the fiscal 1996 
budget.

                              -2-

<PAGE>

The Outlook:  Rates May Rise Again

After its August rate increase, the Fed paused to assess its actions.  
With the Fed ready to move swiftly should price growth inch up above 3%, 
we believe inflation will remain under control.  In this environment, we 
expect short-term rates to climb moderately higher, which should have a 
corresponding effect on your Series' yield.

Once again, it is a pleasure to have you as a shareholder in the 
Prudential Municipal Series Fund -- New York Money Market Series and 
to report our activities to you.

Sincerely,

Lawrence C. McQuade
President

Kenneth Potts
Portfolio Manager
                       
                                 -3-
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                     Portfolio of Investments
NEW YORK MONEY MARKET SERIES                                 August 31, 1994

<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                  Value            
(Unaudited)     (000)            Description          (Note 1)       
<C>           <C>          <S>                      <C>
                           Amherst Ind. Dev. Agcy.
                             Rev.,
                             Gen. Accident Ins.,
                           3.15%, 11/1/94, Ser.
A-1+*          $  3,100      85, S.E.M.O.T........  $  3,100,000
                           Babylon Ind. Dev. Agcy.
                             Rev.,
                             Res. Rec. Rev.,
                           2.95%, 9/1/94, Ser. 89,
A-1+*               200      F.R.D.D..............       200,000
                           Erie Cnty.,
                           4.75%, 8/15/95,
MIG1              3,000      R.A.N................     3,020,622
                           Guilderland Ind. Dev. Agcy. Rev.,
                             Northeastern Ind'l. Park,
                           2.95%, 9/7/94, Ser.
P-1               1,500      93A, F.R.W.D.........     1,500,000
                           Islip Cnty.,
                           4.50%, 8/22/95, Ser.
NR                2,500      94, B.A.N............     2,506,870
                           Monroe Cnty., Ind. Dev.
                             Agcy. Rev.,
                             Gen. Accident Ins.
                             Co.,
                           3.95%, 3/1/95, Ser. 84,
A-1+*             7,000      S.E.M.O.T............     7,000,000
                           Granite Bldg.,
                           2.85%, 9/7/94, Ser. 92,
P-1               2,550      F.R.W.D..............     2,550,000
                           Monroe Cnty., Pub.
                             Impvt.,
                           3.10%, 9/1/94, Ser.
VMIG1             3,675      BT-92, F.R.W.D.......     3,675,000
                           Mt. Pleasant Ind. Dev. Agcy. Rev.,
                             Poll. Ctrl. Rev.,
                             Gen. Motors Corp. Proj.,
                           3.10%, 9/7/94,
VMIG2             6,095      F.R.W.D..............     6,095,000
                           New York City Bankers
                             Trust,
                           3.10%, 9/1/94, Ser.
VMIG1            10,000      B-79, F.R.W.D........    10,000,000
                           New York City Gen.
                             Oblig.,
                             Ser. 95B, R.A.N.,
                           3.234%, 9/1/94,
MIG1              6,900      F.R.M.I.N............     6,900,000
                           3.25%, 9/7/94,
MIG1              5,000      F.R.W.I.N............     5,000,000
                           New York City Hsg. Dev. Corp.,
                             E. 17th St. Property,
                           3.20%, 9/1/94, Ser.
A-1*              4,400      93A, F.R.D.D.........     4,400,000
                           New York City Hsg. Dev. Corp.,
                           James Tower Proj.,
                           3.15%, 9/7/94, Ser.
A-1*           $  3,300      94A, F.R.W.D.........  $  3,300,000
                           Related E. 96th St.
                             Proj.,
                           3.00%, 9/1/94, Ser.
VMIG1            13,500      90A, F.R.W.D.........    13,500,000
                           New York City Ind. Dev.
                             Agcy. Rev.,
                             Japan Airlines,
                           3.30%, 9/1/94, Ser. 91,
A-1+*            24,100      F.R.D.D..............    24,100,000
                           Viola Bakeries,
                           3.00%, 9/7/94, Ser. 90,
VMIG1             2,750      F.R.W.D..............     2,750,000
                           New York City Trust for
                             Cultural Research,
                             Carnegie Hall,
                           3.15%, 9/7/94, Ser. 85,
VMIG1             3,075      F.R.W.D..............     3,075,000
                           New York St. Dorm. Auth. Rev.,
                           2.85%, 9/12/94, Ser.
A-1+*             3,127      89A, T.E.C.P.........     3,127,000
                           Highland Cmnty. Dev.,
                           3.00%, 9/7/94, Ser.
VMIG1             3,250      94A, F.R.W.D.........     3,250,000
                           Mem. Sloan Kettering, T.E.C.P.,
                           2.85%, 9/1/94, Ser.
VMIG1             8,200      89C..................     8,200,000
                           2.85%, 9/13/94, Ser.
VMIG1             5,400      89A..................     5,400,000
                           Rockefeller Univ.,
                           3.25%, 9/7/94, Ser.
Aaa              12,000      91A, F.R.W.D.........    12,000,000
                           Soc. of New York
                             Hosps.,
                           3.00%, 9/20/94, Ser.
VMIG1            10,930      91, T.E.C.P..........    10,930,000
                           St. Francis Center
                             at the Knolls,
                           3.15%, 9/1/94,
VMIG1             4,700      F.R.D.D..............     4,700,000
                           New York St. Energy
                             Res. & Dev. Auth.,
                             Long Island Ltg. Co.
                             Proj.,
                             A.N.N.M.T.,
                           2.85%, 11/1/94, Ser.
VMIG1             4,000      93B..................     4,000,000
                           3.00%, 3/1/95, Ser.
VMIG1             4,000      85B..................     4,000,000
</TABLE>
 
                                      -4-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                     
NEW YORK MONEY MARKET SERIES                                 
<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                  Value            
(Unaudited)     (000)            Description          (Note 1)       
<C>           <C>          <S>                      <C>
                           New York St. Energy
                             Res. & Dev. Auth.,
                           New York St. Elec. & Gas Co.,
                           2.80%, 9/1/94,
A-1+*          $  4,000      T.E.C.P..............  $  4,000,000
                           2.80%, 12/1/94, Ser.
A-1+*             4,500      84A, A.N.N.M.T.......     4,500,000
                           2.95%, 12/7/94, Ser.
VMIG1             3,500      94C, T.E.C.P.........     3,500,000
                           Niagara Mohawk Pwr.
                             Corp., F.R.D.D.,
                           3.20%, 9/1/94, Ser.
P-1               2,600      85B..................     2,600,000
                           3.30%, 9/1/94, Ser.
P-1               6,100      86A..................     6,100,000
                           New York St. Environ.
                             Facs. Corp., Gen.
                             Elec. Corp.,
                           3.25%, 11/9/94, Ser.
P-1               1,400      92A, T.E.C.P.........     1,400,000
                           New York St. Gen.
                             Oblig.,
                           2.80%, 9/8/94, Ser. P,
P-1               5,500      T.E.C.P..............     5,500,000
                           New York St. Hsg. Fin.
                             Auth.,
                             Liberty View Apts.,
                           3.00%, 9/7/94, Ser.
VMIG1             5,400      85A, F.R.W.D.........     5,400,000
                           New York St. Job Dev.
                             Auth., F.R.M.D.,
                           2.75%, 9/1/94, Ser.
VMIG1             1,810      84D..................     1,810,000
                           2.75%, 9/1/94, Ser.
VMIG1             1,145      84E..................     1,145,000
                           2.75%, 9/1/94, Ser.
VMIG1             1,665      84F..................     1,665,000
                           2.90%, 9/1/94, Ser.
VMIG1             1,265      86C..................     1,265,000
                           Niagara Cnty. Ind. Dev.
                             Agcy. Rev., Gen.
                             Abrasive Treibacher,
                           3.25%, 9/7/94, Ser. 91,
P-1               4,600      F.R.W.D..............     4,600,000
                           Oswego Cnty. Ind. Dev.
                             Agcy. Rev., Phillip
                             Morris Co.,
                           3.05%, 9/7/94, Ser. 92,
P-1               6,300      F.R.W.D..............     6,300,000
                           Port Auth. of New York
                             & New Jersey,
                             Kiac Partners,
                             F.R.W.D.,
                           2.95%, 9/7/94, Ser.
VMIG1          $  6,200      3-2..................  $  6,200,000
                           2.95%, 9/7/94, Ser.
VMIG1             4,500      3-3..................     4,500,000
                           Spec. Oblig. Rev.,
                           3.30%, 9/1/94, Ser. 1,
VMIG1             6,100      F.R.D.D..............     6,100,000
                           3.125%, 9/6/94, Ser.
                             93-1,
NR               12,000      F.R.W.D..............    12,000,000
                           Puerto Rico Comnwlth.,
                             Gov't. Dev. Bank.,
                           2.90%, 9/7/94, Ser. 85,
VMIG1             4,900      F.R.W.D..............     4,900,000
                           Sayville Union Free
                             Sch. Dist.,
                           4.50%, 6/8/95,
MIG1              3,800      B.A.N................     3,822,479
                           Smithtown Central Sch.
                             Dist.,
                           4.00%, 6/23/95,
MIG1              8,440      T.A.N................     8,452,936
                           St. Lawrence Cnty. Ind.
                             Dev. Agcy. Rev.,
                             Clarkson Univ. Proj.,
                           3.15%, 9/1/94, Ser. 90,
VMIG1             3,000      F.R.W.D..............     3,000,000
                           Syracuse,
                           4.00%, 6/16/95, B.A.N.,
NR                4,188      T.R.A.N..............     4,200,666
                           Yates Cnty. Ind. Dev. Agcy. Rev.,
                             Clearplass Containers Inc.,
                           3.10%, 9/1/94, Ser.
A-1*              1,575      92A, F.R.W.D.........     1,575,000
                                                    ------------
                           Total Investments--97.7%
                           (amortized cost--
                             $262,815,573**)......   262,815,573
                           Other assets in excess
                             of
                             liabilities--2.3%....     6,257,624
                                                    ------------
                           Net Assets--100%.......  $269,073,197
                                                    ------------
                                                    ------------
</TABLE>
 
                                      -5-     See Notes to Financial Statements.
 
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                     
NEW YORK MONEY MARKET SERIES                                 

(a) The following abbreviations are used in portfolio descriptions:
    A.N.N.M.T.--Annual Mandatory Tender.
     B.A.N.--Bond Anticipation Note.
     F.R.D.D.--Floating Rate (Daily) Demand Note #.
     F.R.M.D.--Floating Rate (Monthly) Demand Note #.
     F.R.M.I.N.--Floating Rate (Monthly) Index Note #.
     F.R.W.D.--Floating Rate (Weekly) Demand Note #.
     F.R.W.I.N.--Floating Rate (Weekly) Index Note #.
     R.A.N.--Revenue Anticipation Note.
     S.E.M.O.T.--Semi-Annual Optional Tender.
     T.A.N.--Tax Anticipation Note.
     T.E.C.P.--Tax-Exempt Commercial Paper.
     T.R.A.N.--Tax Revenue Anticipation Note.
 # For purposes of amortized cost valuation, the maturity date of such
   securities is considered to be the later of the next date on which the
   security can be redeemed at par or the next date on which the rate of
   interest is adjusted.
 * Standard & Poor's rating.
** The cost of securities for federal income tax purposes is substantially the
   same as for financial reporting purposes.
NR--Not Rated by Moody's or Standard & Poor's.
The Fund's current Statement of Additional Information contains a description of
Moody's and Standard & Poor's ratings.
                                      -6-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW YORK MONEY MARKET SERIES
 Statement of Assets and Liabilities
<TABLE>
<CAPTION>
Assets                                                                                      August 31, 1994
                                                                                            ---------------
<S>                                                                                         <C>
Investments, at amortized cost which approximates market value...........................    $ 262,815,573
Cash.....................................................................................           71,164
Receivable for investments sold..........................................................       15,206,882
Receivable for Series shares sold........................................................        1,338,195
Interest receivable......................................................................          954,941
Other assets.............................................................................            6,725
                                                                                            ---------------
    Total assets.........................................................................      280,393,480
                                                                                            ---------------
Liabilities
Payable for investments purchased........................................................        7,000,000
Payable for Series shares reacquired.....................................................        3,962,481
Accrued expenses and other liabilities...................................................          120,871
Management fee payable...................................................................          117,428
Dividends payable........................................................................          102,621
Distribution fee payable.................................................................           15,872
Deferred trustees' fees..................................................................            1,010
                                                                                            ---------------
    Total liabilities....................................................................       11,320,283
                                                                                            ---------------
Net Assets...............................................................................    $ 269,073,197
                                                                                            ---------------
                                                                                            ---------------
Net assets were comprised of:
  Shares of beneficial interest, at $.01 par value.......................................    $   2,690,732
  Paid-in capital in excess of par.......................................................      266,382,465
                                                                                            ---------------
  Net assets, August 31, 1994............................................................    $ 269,073,197
                                                                                            ---------------
                                                                                            ---------------
Net asset value, offering price and redemption price per share ($269,073,197 /
  269,073,197 shares
  of beneficial interest issued and outstanding; unlimited number of shares
  authorized)............................................................................            $1.00
                                                                                            ---------------
                                                                                            ---------------
</TABLE>
 
See Notes to Financial Statements.
                                      -7-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW YORK MONEY MARKET SERIES
 Statement of Operations
<TABLE>
<CAPTION>
                                            Year Ended
                                            August 31,
Net Investment Income                          1994
                                          ---------------
<S>                                       <C>
Income
  Interest.............................     $   7,155,616
                                          ---------------
Expenses
  Management fee.......................         1,402,462
  Distribution fee.....................           350,615
  Transfer agent's fees and expenses...           151,000
  Custodian's fees and expenses........           125,000
  Reports to shareholders..............            55,000
  Registration fees....................            32,000
  Legal fees...........................            15,000
  Audit fee............................            10,000
  Insurance expense....................             8,500
  Trustees' fees.......................             3,375
  Miscellaneous........................             4,695
                                          ---------------
    Total expenses.....................         2,157,647
                                          ---------------
Net investment income..................         4,997,969
                                          ---------------
Net Increase in Net Assets
Resulting from Operations..............     $   4,997,969
                                          ---------------
                                          ---------------
</TABLE>
 
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW YORK MONEY MARKET SERIES
 Statement of Changes in Net Assets
<TABLE>
<CAPTION>
                               Year Ended August 31,
Increase (Decrease)        -----------------------------
in Net Assets                  1994            1993
                           -------------   -------------
<S>                        <C>             <C>
Operations
  Net investment
  income.................  $   4,997,969   $   4,821,146
                           -------------   -------------
  Net increase in net
    assets resulting from
    operations...........      4,997,969       4,821,146
                           -------------   -------------
Dividends to
  shareholders...........     (4,997,969)     (4,821,146)
                           -------------   -------------
Series share transactions
  (at $1 per share)
  Net proceeds from
    shares sold..........    956,452,031   1,012,741,172
  Net asset value of
    shares issued to
    shareholders in
    reinvestment of
    dividends............      4,807,678       4,672,839
  Cost of shares
  reacquired.............   (978,490,262)   (980,895,234)
                           -------------   -------------
  Net increase (decrease)
    in net assets from
    Series share
    transactions.........    (17,230,553)     36,518,777
                           -------------   -------------
Total increase
  (decrease).............    (17,230,553)     36,518,777
Net Assets
Beginning of year........    286,303,750     249,784,973
                           -------------   -------------
End of year..............  $ 269,073,197   $ 286,303,750
                           -------------   -------------
                           -------------   -------------
</TABLE>
 
See Notes to Financial Statements.        See Notes to Financial Statements.
                                      -8-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW YORK MONEY MARKET SERIES
 Notes to Financial Statements
   Prudential Municipal Series Fund (the ``Fund'') is registered under the
Investment Company Act of 1940 as an open-end investment company. The Fund was
organized as a Massachusetts business trust on May 18, 1984 and consists of
seventeen series. The monies of each series are invested in separate,
independently managed portfolios. The New York Money Market Series (the
``Series'') commenced investment operations in April, 1985. The Series is
diversified and seeks to achieve its investment objective of providing the
highest level of income that is exempt from New York State, New York City and
federal income taxes with a minimum of risk by investing in ``investment grade''
tax-exempt securities having a maturity of thirteen months or less whose ratings
are within the two highest ratings categories by two nationally recognized
statistical rating organizations, or if not rated, are of comparable quality.
The ability of the issuers of the securities held by the Series to meet their
obligations may be affected by economic developments in a specific state,
industry or region.
                              
Note 1. Accounting            The following is a summary
Policies                      of significant accounting poli-
                              cies followed by the Fund, and the Series, in the
preparation of its financial statements.
Securities Valuations: Portfolio securities of the Series are valued at
amortized cost, which approximates market value. The amortized cost method of
valuation involves valuing a security at its cost on the date of purchase and
thereafter assuming a constant amortization to maturity of any discount or
premium.
   All securities are valued as of 4:30 P.M., New York time.
Securities Transactions and Investment Income: Securities transactions are
recorded on the trade date. Realized gains and losses on sales of investments
are calculated on the identified cost basis. Interest income is recorded on the
accrual basis.
Federal Income Taxes: For federal income tax purposes, each series in the Fund
is treated as a separate taxpaying entity. It is the intent of the Series to
continue to meet the requirements of the Internal Revenue Code applicable to
regulated investment companies and to distribute all of its net income to
shareholders. For this reason and because substantially all of the Series' gross
income consists of tax-exempt interest, no federal income tax provision is
required.
Dividends: The Series declares daily dividends from net investment income.
Payment of dividends is made monthly.
   Income distributions and capital gain distributions are determined in
accordance with income tax regulations which may differ from generally accepted
accounting principles.
                              
Note 2. Agreements            The Fund has a management
                              agreement with Prudential Mutual Fund Management,
Inc. (``PMF''). Pursuant to this agreement, PMF has responsibility for all
investment advisory services and supervises the subadviser's performance of such
services. PMF has entered into a subadvisory agreement with The Prudential
Investment Corporation (``PIC''); PIC furnishes investment advisory services in
connection with the management of the Fund. PMF pays for the cost of the
subadviser's services, the compensation of officers of the Fund, occupancy and
certain clerical and bookkeeping costs of the Fund. The Fund bears all other
costs and expenses.
   The management fee paid PMF is computed daily and payable monthly, at an
annual rate of .50 of 1% of the average daily net assets of the Series.
   The Fund has a distribution agreement with Prudential Mutual Fund
Distributors, Inc. (``PMFD''). To reimburse PMFD for its expenses incurred
pursuant to a plan of distribution, the Series pays PMFD a reimbursement,
accrued daily and payable monthly, at an annual rate of .125 of 1% of the
Series' average daily net assets. PMFD pays various broker-dealers, including
Prudential Securities Incorporated (``PSI'') and Pruco Securities Corporation,
affiliated broker-dealers, for account servicing fees and other expenses
incurred by such broker-dealers.
   PMFD is a wholly-owned subsidiary of PMF; PSI, PMF and PIC are (indirect)
wholly-owned subsidiaries of The Prudential Insurance Company of America.
                              
Note 3. Other                 Prudential Mutual Fund Ser-
Transactions                  vices, Inc. (``PMFS''), a 
with Affiliates               wholly-owned subsidiary of 
                              PMF, serves as the Fund's transfer agent. During
the year ended August 31, 1994, the Series incurred fees of approximately
$131,000 for the services of PMFS. As of August 31, 1994, approximately $10,000
of such fees were due to PMFS. Transfer agent fees and expenses in the Statement
of Operations include certain out-of-pocket expenses paid to non-affiliates.
                                      -9-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 NEW YORK MONEY MARKET SERIES
 Financial Highlights
<TABLE>
<CAPTION>
                                                                                 Year Ended August 31,
                                                             -------------------------------------------------------------
PER SHARE OPERATING PERFORMANCE:                                 1994          1993        1992        1991         1990
                                                             ------------    --------    --------    --------     --------
<S>                                                          <C>             <C>         <C>         <C>          <C>
Net asset value, beginning of year........................     $     1.00    $   1.00    $   1.00    $   1.00     $   1.00
Net investment income and net realized gains..............            .02         .02         .03         .04          .05
Dividends and distributions to shareholders...............           (.02)       (.02)       (.03)       (.04)        (.05)
                                                             ------------    --------    --------    --------     --------
Net asset value, end of year..............................     $     1.00    $   1.00    $   1.00    $   1.00     $   1.00
                                                             ------------    --------    --------    --------     --------
                                                             ------------    --------    --------    --------     --------
TOTAL RETURN#:............................................           1.80%       1.80%       2.93%       4.37%        5.14%
RATIOS/SUPPLEMENTAL DATA:
Net assets, end of year (000).............................     $  269,073    $286,304    $249,785    $236,361     $226,758
Average net assets (000)..................................     $  280,492    $275,640    $248,557    $245,494     $218,423
Ratios to average net assets:
  Expenses, including distribution fee....................            .77%        .75%        .76%        .79%         .75%
  Expenses, excluding distribution fee....................            .64%        .63%        .63%        .66%         .62%
  Net investment income...................................           1.78%       1.75%       2.83%       4.23%        4.99%
- ---------------
# Total return includes reinvestment of dividends and distributions.
</TABLE>
See Notes to Financial Statements.
                                      -10-
 <PAGE>
<PAGE>
                          INDEPENDENT AUDITORS' REPORT
The Shareholders and Board of Trustees
Prudential Municipal Series Fund, New York Money Market Series
   We have audited the accompanying statement of assets and liabilities of
Prudential Municipal Series Fund, New York Money Market Series, including the
portfolio of investments, as of August 31, 1994, the related statements of
operations for the year then ended and of changes in net assets for each of the
two years in the period then ended, and the financial highlights for each of the
five years in the period then ended. These financial statements and financial
highlights are the responsibility of the Fund's management. Our responsibility
is to express an opinion on these financial statements and financial highlights
based on our audits.
   We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements and financial
highlights are free of material misstatement. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements. Our procedures included confirmation of the securities owned as of
August 31, 1994 by correspondence with the custodian and brokers; where replies
were not received from brokers, we performed other auditing procedures. An audit
also includes assessing the accounting principles used and significant estimates
made by management, as well as evaluating the overall financial statement
presentation. We believe that our audits provide a reasonable basis for our
opinion.
   In our opinion, such financial statements and financial highlights present
fairly, in all material respects, the financial position of Prudential Municipal
Series Fund, New York Money Market Series, as of August 31, 1994, the results of
its operations, the changes in its net assets, and its financial highlights for
the respective stated periods in conformity with generally accepted accounting
principles.
Deloitte & Touche LLP
New York, New York
October 17, 1994

                         FEDERAL INCOME TAX INFORMATION
   We are required by the Internal Revenue Code to advise you within 60 days of
the Series' fiscal year end (August 31, 1994) as to the federal tax status of
dividends and distributions paid by the Series during such fiscal year.
Accordingly, we are advising you that in the fiscal year ended August 31, 1994,
dividends paid from net investment income totalling $.02 per share were all
federally tax-exempt interest dividends.
   In January 1995, you will be advised on IRS Form 1099 DIV or substitute 1099
DIV as to the federal tax status of the distributions received by you in
calendar year 1994.
                                      -11-
<PAGE>
Trustees
Edward D. Beach
Eugene C. Dorsey
Delayne Dedrick Gold
Harry A. Jacobs, Jr.
Lawrence C. McQuade
Thomas T. Mooney
Thomas H. O'Brien
Richard A. Redeker
Nancy H. Teeters

Officers
Lawrence C. McQuade, President
Robert F. Gunia, Vice President
Susan C. Cote, Treasurer
S. Jane Rose, Secretary
Ronald Amblard, Assistant Secretary
Deborah A. Docs, Assistant Secretary

Manager
Prudential Mutual Fund Management, Inc.
One Seaport Plaza
New York, NY 10292

Investment Adviser
The Prudential Investment Corporation
Prudential Plaza
Newark, NJ 07101

Distributor
Prudential Mutual Fund Distributors, Inc.
One Seaport Plaza
New York, NY 10292

Custodian
State Street Bank and Trust Company
One Heritage Drive
North Quincy, MA 02171

Transfer Agent
Prudential Mutual Fund Services, Inc.
P.O. Box 15005
New Brunswick, NJ 08906

Independent Accountants
Deloitte & Touche LLP
1633 Broadway
New York, NY 10019

Legal Counsel
Gardner, Carton & Douglas
Quaker Tower
321 North Clark Street
Chicago, IL 60610-4795

Prudential Mutual Funds
One Seaport Plaza
New York, NY 10292
Toll free (800) 225-1852, Collect (908) 417-7555

This report is not authorized for distribution to 
prospective investors unless preceded or accompanied 
by a current prospectus.

                                         MF 127E
74435M721         (LOGO)           Cat. #642401A













<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                      Portfolio of Investments
OHIO SERIES                                                    August 31, 1994
<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                  Value            
(Unaudited)     (000)          Description(a)         (Note 1)       
<C>           <C>          <S>                      <C>
                           LONG-TERM INVESTMENTS--98.7%
                           Akron, Bath & Copley
                             Twnshps.,
                             Hosp. Dist. Rev.,
                             Childrens Hosp. Med.
                             Ctr.,
                           5.25%, 11/15/20,
Aaa            $  1,000      A.M.B.A.C............  $    872,940
                           Summa Health Systems
                             Proj.,
                           5.75%, 11/15/08, Ser.
A                 3,465      A....................     3,321,930
                           Akron, Gen. Oblig.,
A                   200    10.50%, 12/1/04........       277,716
                           4.50%, 12/1/12,
Aaa                 645      F.S.A................       530,725
                           Allen Cnty. Wtr. & Swr.
                             Dist.,
                           7.80%, 12/1/08,
Aaa               1,000(D)   A.M.B.A.C............     1,131,150
                           Bellefontaine City Sch.
                             Dist., A.M.B.A.C.,
Aaa                 495    Zero Coupon, 12/1/06...       252,227
Aaa                 485    Zero Coupon, 12/1/07...       231,505
Aaa                 485    Zero Coupon, 12/1/08...       216,519
Aaa                 390    Zero Coupon, 12/1/09...       162,591
Aaa                 390    Zero Coupon, 12/1/10...       152,201
Aaa                 465    Zero Coupon, 12/1/11...       170,260
                           Berea City Sch. Dist.,
                           5.00%, 12/15/17,
Aaa               4,375      A.M.B.A.C............     3,768,187
                           Carroll Cnty. Econ.
                             Dev. Rev., Great
                             Trail Lake Ctr.,
                           11.75%, 8/1/14,
NR                  690      F.H.A................       784,820
                           City of Toledo,
Aaa               1,000    6.10%, 12/1/14.........       998,730
                           Cleveland City Sch.
                             Dist.,
                             Gen. Oblig.,
                             Sch. Impvt., Ser. B,
                             F.G.I.C.,
Aaa                 490    Zero Coupon, 6/1/05....       273,454
Aaa                 400    Zero Coupon, 6/1/06....       209,512
Aaa                 315    Zero Coupon, 6/1/07....       154,611
Aaa                 550    Zero Coupon, 12/1/08...       245,537
                           Columbus Citation Hsg.
                             Dev. Corp., Mtge.
                             Rev.,
                           7.625%, 1/1/22,
AA*               1,885(D)   F.H.A................     2,236,854
                           Columbus, Gen. Oblig.,
                           6.00%, 9/15/10, Ser.
Aa1               1,000(D)   1....................     1,055,660
                           6.00%, 9/15/11, Ser.
Aa1               1,000(D)   1....................     1,055,660
                           Mun. Arpt. No. 32,
Aa1                 435    7.15%, 7/15/06.........       469,387
                           Columbus, Gen. Oblig.,
                           Swr. Impvt. No. 26,
Aa1            $  2,000    6.00%, 9/15/09.........  $  2,025,060
                           Cuyahoga Cnty.,
                             Bldg. Impvt. Bond,
                           7.40%, 10/1/09, Ser.
NR                1,500(D)   83...................     1,670,055
                           Cuyahoga Cnty., Hosp.
                             Auth. Rev., Brentwood
                             Hosp.,
Baa1              1,600    9.625%, 11/1/14........     1,704,144
                           Dayton Arpt. Rev.,
                             James M. Cox Int'l.
                             Arpt.,
                           8.25%, 1/1/16,
Aaa               3,500      A.M.B.A.C............     3,746,750
                           Dayton, Gen. Oblig.,
                           7.00%, 12/1/07,
Aaa                 480      M.B.I.A..............       538,853
                           Dayton Wtr. Sys. Rev.,
                             Mtge. Ref.,
Aaa                 600@(D) 10.25%, 12/1/10........      655,452
                           Dublin City Sch. Dist.,
                             Franklin,
                             Delaware & Union Co.,
                           Zero Coupon, 12/1/05,
Aaa               1,000      A.M.B.A.C............       540,080
                           East Cleveland Rev.,
                             Local Gov't. Fund
                             Notes,
NR                1,110    7.90%, 12/1/97.........     1,223,153
                           Franklin Cnty. Hosp.
                             Rev.,
A                 1,550    5.875%, 12/1/13........     1,412,608
                           Holy Cross Hlth. Sys.,
                           7.65%, 6/1/10, Ser. B,
Aaa               2,500(D)   A.M.B.A.C............     2,866,225
                           Gahanna Jefferson City
                             Sch. Dist., Gen.
                             Oblig.,
                           Zero Coupon, 12/1/09,
Aaa                 445      A.M.B.A.C............       185,521
                           Greene Cnty. Swr. Sys.
                             Rev.,
                           Zero Coupon, 12/1/08,
Aaa                 450      A.M.B.A.C............       200,894
                           Hamilton Cnty. Elec.
                             Sys. Mtge. Rev.,
                           8.00%, 10/15/22, Ser.
Aaa               3,000@(D)   B, F.G.I.C...........    3,407,880
                           Hamilton Cnty. Gas Sys.
                             Rev.,
                           4.75%, 10/15/23, Ser.
Aaa               3,750      A, M.B.I.A...........     3,020,887
</TABLE>
 
                                      -5-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                      
OHIO SERIES                                                    
<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                  Value            
(Unaudited)     (000)          Description(a)         (Note 1)       
<C>           <C>          <S>                      <C>
                           Hamilton Cnty. Swr.
                             Sys. Rev., Met. Swr.
                             Dist. of Greater
                             Cincinnati,
                           9.50%, 12/1/05, Ser.
Aaa            $    500(D)   A....................  $    546,510
                           Kettering Cnty., Gen.
                             Oblig.,
Aa                1,155(D) 7.30%, 12/1/06.........     1,312,923
                           Logan Hocking Local
                             Sch. Dist., Hocking,
                             Perry & Vinton Co.,
                             Gen. Oblig.,
                           Zero Coupon, 12/1/09,
Aaa                 650      A.M.B.A.C............       270,985
                           Loveland City Sch.
                             Dist.,
                             Gen. Oblig.,
A*                3,000    7.10%, 12/1/09.........     3,269,190
                           Lucas Cnty. Hosp. Rev.,
                             Toledo Hosp., Impvt.
                             & Ref., M.B.I.A.,
Aaa               2,000    5.00%, 11/15/13........     1,750,840
Aaa               6,000    5.00%, 11/15/22........     5,038,620
                           Miami Cnty. Hosp. Facs.
                             Rev.,
                             Upper Valley Med.
                             Ctr. Proj.,
                           6.50%, 5/1/21, Ser. A,
Aaa                 500      M.B.I.A..............       513,590
                           Montgomery Cnty. Swr.
                             Sys. Rev., Greater
                             Moraine, Beaver
                             Creek, F.G.I.C.,
Aaa               1,000    Zero Coupon, 9/1/05....       550,540
Aaa                 500    Zero Coupon, 9/1/07....       242,020
                           Mount Vernon City Sch.
                             Dist., Gen. Oblig.,
                             F.G.I.C.,
Aaa                 500    7.50%, 12/1/14.........       565,630
Aaa               1,000    5.85%, 12/1/19.........       975,420
                           Newark Ltd. Tax Gen.
                             Oblig., Wtr. Impvt.,
                             A.M.B.A.C.
Aaa                 805    Zero Coupon, 12/1/06...       410,188
                           Ohio St. Air Quality
                             Dev. Auth. Rev.,
                             Poll. Ctrl.,
                             Cincinnati Gas &
                             Elec. Co.,
                           5.45%, 1/1/24, Ser. B,
Aaa               2,400      M.B.I.A..............     2,178,840
                           Cleveland Co. Proj.,
                           8.00%, 12/1/13,
Aaa               2,500@     F.G.I.C..............     2,902,650
                           Ohio St. Air Quality
                             Dev. Auth. Rev.,
                             Poll. Ctrl.,
                           Edison Proj.,
                           7.45%, 3/1/16, Ser. A,
Aaa            $  3,750      F.G.I.C..............  $  4,163,737
                           Ohio St. Bldg. Auth.,
                             Columbus St. Bldg.
                             Proj.,
                           7.75%, 10/1/07, Ser.
A                   750(D)   A....................       842,280
                           Das Data Ctr. Proj.,
A                   615    6.00%, 10/1/08.........       628,468
                           St. Correctional Facs.,
                           8.00%, 8/1/06, Ser.
Aaa                 600(D)   A....................       670,614
A                 2,450    5.90%, 10/1/07.........     2,490,082
                           8.00%, 8/1/08, Ser.
Aaa                 500(D)   A....................       558,845
                           Workers Comp.--W. Green
                             Bldg. A
A                 1,175    4.75%, 4/1/14..........       960,210
                           Ohio St. Higher Edl.
                             Fac. Comn. Rev.,
                             Case Western Resv.
                             Univ.,
Aa                1,410    6.25%, 10/1/16.........     1,426,807
                           7.70%, 10/1/18, Ser.
Aa                1,000      A....................     1,094,880
                           6.50%, 10/1/20, Ser.
Aa                  750      B....................       778,853
                           Oberlin Coll.,
Aaa               1,000(D) 7.375%, 10/1/14........     1,125,750
Aaa                 500(D) 9.25%, 10/1/15.........       535,490
                           Univ. of Dayton Proj.,
                           5.80%, 12/1/19,
Aaa                 750      F.G.I.C..............       723,915
                           Ohio St. Mtge. Rev.,
                           8.15%, 8/1/17, Ser. A,
AAA*              3,500      F.H.A................     3,895,570
                           Ohio St. Poll. Ctrl.
                             Rev.,
                             Standard Oil Co.,
A1                1,350    6.75%, 12/1/15.........     1,470,515
                           Ohio St. Univ., Gen.
                             Receipts,
                           5.75%, 12/1/09, Ser.
A1                1,500      A2...................     1,486,335
                           5.875%, 12/1/12, Ser.
A1                  750      A1...................       729,480
                           Ohio St. Wtr. Dev.
                             Auth. Rev.,
                           7.50%, 12/1/08, Ser.
Aaa               1,200(D)   I....................     1,331,688
                           5.50%, 12/1/11,
Aaa                 915      A.M.B.A.C............       870,870
                           Ottawa Cnty. San. Sew.
                             Sys. Rev., Danbury
                             Proj.,
                           7.375%, 10/1/14,
Aaa               1,000(D)   A.M.B.A.C............     1,127,200
</TABLE>
 
                                      -6-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                      
OHIO SERIES                                                    
<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                  Value            
(Unaudited)     (000)          Description(a)         (Note 1)       
<C>           <C>          <S>                      <C>
                           Oxford Hosp. Facs.
                             Rev.,
                             1st Mtge., McCullough
                             Hyde Mem.,
NR             $  1,445    8.00%, 5/1/17..........  $  1,513,609
                           Pickerington Local Sch.
                             Dist., Gen. Oblig.,
                             A.M.B.A.C.,
Aaa                 890    Zero Coupon, 12/1/08...       397,323
Aaa                 935    Zero Coupon, 12/1/09...       389,801
Aaa                 525    Zero Coupon, 12/1/13...       168,231
                           Puerto Rico Comnwlth.,
                             Aqueduct & Swr. Auth.
                             Rev.,
                           7.875%, 7/1/17, Ser.
Ba                1,000      A....................     1,109,300
                           Gen. Oblig., M.B.I.A.,
                           8.344%, 7/1/08, Ser.
Aaa               1,000(D)(D)   A....................    1,012,500
Aaa               1,500    5.25%, 7/1/18..........     1,356,435
                           Puerto Rico Pub. Bldgs.
                             Auth.,
                             Gtd. Pub. Ed. & Hlth.
                             Facs.,
                           Zero Coupon, 7/1/06,
Baa1              3,000      Ser. J...............     1,528,530
                           Rural Lorain Cnty. Wtr.
                             Auth. Res. Rev.,
                           7.70%, 10/1/08,
Aaa               2,000(D)   A.M.B.A.C............     2,248,760
                           Sandusky Cnty., Gen.
                             Oblig.,
                           6.25%, 12/1/19,
Aaa                 500      M.B.I.A..............       508,505
                           Scioto Cnty. Hosp. Fac.
                             Rev., Portsmouth
                             Proj.,
                           7.625%, 5/15/08, Ser.
                             B,
Aaa               2,290      M.B.I.A..............     2,536,290
                           Shawnee St. Univ.,
                             Gen. Receipts,
                           6.00%, 6/1/14, Ser. B,
Aaa                 500      A.M.B.A.C............       498,225
                           Solon Sch. Dist., Gen.
                             Oblig.,
                             Graphic Laminating
                             Inc. Proj.,
Aa                2,000(D) 7.15%, 12/1/13.........     2,272,120
                           Student Loan Funding
                             Corp., Cincinnati
                             Rev., Ser. A,
A                 1,400    7.20%, 8/1/03..........     1,492,218
A                 2,000    7.25%, 2/1/08..........     2,087,980
                           Sugarcreek Local Sch.
                             Dist.,
                           Zero Coupon, 12/1/08,
Aaa                 500      F.G.I.C..............       223,215
                           Summit Cnty. Ind. Dev.
                             Rev., Century
                             Products, Gerber
                             Foods,
A2             $  3,250    7.75%, 11/1/05.........  $  3,522,837
                           Tuscarawas Cnty. Hosp.
                             Fac. Rev., Union
                             Hosp. Proj., Ser. A,
Baa                 450    6.375%, 10/1/11........       435,659
Baa               1,250    6.50%, 10/1/21.........     1,149,012
                           Univ. of Cincinnati,
                             Gen. Receipts,
                           7.30%, 6/1/09, Ser.
Aaa               1,000(D)   E1...................     1,100,940
                           7.00%, 6/1/11, Ser.
A1                1,000      L....................     1,083,220
                           Univ. of Toledo,
                             Gen. Receipts,
                           7.70%, 6/1/18,
Aaa               1,000(D)   M.B.I.A..............     1,116,540
                           Virgin Islands Pub.
                             Fin. Auth. Rev., Hwy.
                             Trans. Trust Fund,
                           7.25%, 10/1/18, Ser.
NR                1,000      A....................     1,031,620
                           Virgin Islands Terr.,
                             Hugo Ins. Claims Fund
                             Prog.,
                           7.75%, 10/1/06, Ser.
NR                  460      91...................       502,978
                           Virgin Islands Wtr. &
                             Pwr. Auth.,
                             Elec. Sys. Rev.,
                           7.40%, 7/1/11, Ser.
NR                1,000      A....................     1,044,600
                           Wtr. Sys. Rev.,
                           8.50%, 1/1/10, Ser.
NR                1,000      A....................     1,098,560
                           Woodmore Indpt. Sch.
                             Dist., Gen. Oblig.,
                             A.M.B.A.C.,
Aaa                 490    Zero Coupon, 12/1/05...       266,134
Aaa                 480    Zero Coupon, 12/1/06...       244,584
                           Youngstown, Gen.
                             Oblig.,
                           6.125%, 12/1/14,
Aaa                 300      M.B.I.A..............       302,925
                                                    ------------
                           Total Investments--98.7%
                           (cost $115,698,184;
                             Note 4)..............   121,451,924
                           Other assets in excess
                             of
                             liabilities--1.3%....     1,572,576
                                                    ------------
                           Net Assets--100%.......  $123,024,500
                                                    ------------
                                                    ------------
</TABLE>
 
                                      -7-     See Notes to Financial Statements.
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                      
OHIO SERIES                                                    

(a) The following abbreviations are used in portfolio descriptions:
      A.M.B.A.C.--American Municipal Bond Assurance Corporation.
      F.G.I.C.--Financial Guaranty Insurance Company.
      F.H.A.--Federal Housing Administration.
      F.S.A.--Financial Security Assurance.
      M.B.I.A.--Municipal Bond Insurance Association.
          @ Pledged as initial margin on financial futures
            contracts.
          * Standard & Poor's rating.
        (D) Prerefunded issues are secured by escrowed cash
            and/or direct U.S. guaranteed obligations.
     (D)(D) Inverse floating rate bond. The coupon is
            inversely indexed to a floating interest rate.
            The rate shown is the rate at period end.
 
NR--Not Rated by Moody's or Standard & Poor's.
The Fund's current Statement of Additional Information contains a description of
Moody's and Standard & Poor's ratings.
                                      -8-     See Notes to Financial Statements.
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 OHIO SERIES
 Statement of Assets and Liabilities
<TABLE>
<CAPTION>
Assets                                                                                      August 31, 1994
                                                                                            ---------------
<S>                                                                                         <C>
Investments, at value (cost $115,698,184)................................................    $ 121,451,924
Interest receivable......................................................................        2,125,554
Receivable for Series shares sold........................................................          140,182
Other assets.............................................................................            3,300
                                                                                            ---------------
  Total assets...........................................................................      123,720,960
                                                                                            ---------------
Liabilities
Bank overdraft...........................................................................          252,301
Payable for Series shares reacquired.....................................................          160,863
Dividends payable........................................................................           83,813
Accrued expenses.........................................................................           81,446
Management fee payable...................................................................           52,038
Distribution fee payable.................................................................           50,479
Due to broker-variation margin...........................................................           14,510
Deferred trustees' fees..................................................................            1,010
                                                                                            ---------------
  Total liabilities......................................................................          696,460
                                                                                            ---------------
Net Assets...............................................................................    $ 123,024,500
                                                                                            ---------------
                                                                                            ---------------
Net assets were comprised of:
  Shares of beneficial interest, at par..................................................    $     104,922
  Paid-in capital in excess of par.......................................................      117,685,937
                                                                                            ---------------
                                                                                               117,790,859
  Accumulated net realized loss on investments...........................................         (477,599)
  Net unrealized appreciation on investments.............................................        5,711,240
                                                                                            ---------------
  Net assets, August 31, 1994............................................................    $ 123,024,500
                                                                                            ---------------
                                                                                            ---------------
Class A:
  Net asset value and redemption price per share
    ($4,749,275 / 405,188 shares of beneficial interest issued and outstanding)..........           $11.72
  Maximum sales charge (3.0% of offering price)..........................................              .36
                                                                                            ---------------
  Maximum offering price to public.......................................................           $12.08
                                                                                            ---------------
                                                                                            ---------------
Class B:
  Net asset value, offering price and redemption price per share
    ($118,269,998 / 10,086,517 shares of beneficial interest issued and outstanding).....           $11.73
                                                                                            ---------------
                                                                                            ---------------
Class C:
  Net asset value, offering price and redemption price per share
    ($5,226.57 / 445.72 shares of beneficial interest issued and outstanding)............           $11.73
                                                                                            ---------------
                                                                                            ---------------
</TABLE>
 
See Notes to Financial Statements.
                                      -9-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 OHIO SERIES
 Statement of Operations
<TABLE>
<CAPTION>
                                         Year Ended
                                         August 31,
Net Investment Income                       1994
                                         -----------
<S>                                      <C>
Income
  Interest............................   $ 7,928,367
                                         -----------
Expenses
  Management fee......................       630,490
  Distribution fee--Class A...........         4,733
  Distribution fee--Class B...........       606,826
  Custodian's fees and expenses.......       106,000
  Transfer agent's fees and
  expenses............................        80,000
  Reports to shareholders.............        44,000
  Registration fees...................        30,000
  Legal fees..........................        15,000
  Audit fee...........................        10,500
  Trustees' fees......................         3,375
  Miscellaneous.......................         8,856
                                         -----------
    Total expenses....................     1,539,780
                                         -----------
Net investment income.................     6,388,587
                                         -----------
Realized and Unrealized
Gain (Loss) on Investments
Net realized gain on:
  Investment transactions.............       513,514
  Financial futures transactions......       287,132
                                         -----------
                                             800,646
                                         -----------
Net change in unrealized appreciation/depreciation
  on:
  Investments.........................    (7,701,534)
  Financial futures contracts.........       (40,313)
                                         -----------
                                          (7,741,847)
                                         -----------
Net loss on investments...............    (6,941,201)
                                         -----------
Net Decrease in Net Assets Resulting
from Operations.......................   $  (552,614)
                                         -----------
                                         -----------
</TABLE>
 
 PRUDENTIAL MUNICIPAL SERIES FUND
 OHIO SERIES
 Statement of Changes in Net Assets
<TABLE>
<CAPTION>
                              Year Ended August 31,
Increase (Decrease)        ----------------------------
in Net Assets                  1994            1993
                           ------------    ------------
<S>                        <C>             <C>
Operations
  Net investment
  income.................  $  6,388,587    $  6,034,400
  Net realized gain on
    investment
    transactions.........       800,646       1,222,277
  Net change in
    unrealized
    appreciation of
    investments..........    (7,741,847)      5,311,037
                           ------------    ------------
  Net increase (decrease)
    in net assets
    resulting from
    operations...........      (552,614)     12,567,714
                           ------------    ------------
Dividends from net
  investment income (Note
  1)
    Class A..............      (258,026)       (165,299)
    Class B..............    (6,130,561)     (5,869,101)
                           ------------    ------------
                             (6,388,587)     (6,034,400)
                           ------------    ------------
Series share transactions
  (Note 5)
  Net proceeds from
  shares
    sold.................    16,655,835      21,565,565
  Net asset value of
    shares
    issued in
    reinvestment of
    dividends............     3,713,106       3,491,240
  Cost of shares
  reacquired.............   (16,986,967)     (9,300,053)
                           ------------    ------------
  Net increase in net
    assets from Series
    share transactions...     3,381,974      15,756,752
                           ------------    ------------
Total increase
  (decrease).............    (3,559,227)     22,290,066
Net Assets
Beginning of year........   126,583,727     104,293,661
                           ------------    ------------
End of year..............  $123,024,500    $126,583,727
                           ------------    ------------
                           ------------    ------------
</TABLE>
 
See Notes to Financial Statements.        See Notes to Financial Statements.
                                      -10-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 OHIO SERIES
 Notes to Financial Statements
   Prudential Municipal Series Fund (the ``Fund'') is registered under the
Investment Company Act of 1940, as an open-end investment company. The Fund was
organized as a Massachusetts business trust on May 18, 1984 and consists of
seventeen series. The monies of each series are invested in separate,
independently managed portfolios. The Ohio Series (the ``Series'') commenced
investment operations in September, 1984. The Series is diversified and seeks to
achieve its investment objective of obtaining the maximum amount of income
exempt from federal and applicable state income taxes with the minimum of risk
by investing in ``investment grade'' tax-exempt securities whose ratings are
within the four highest ratings categories by a nationally recognized
statistical rating organization or, if not rated, are of comparable quality. The
ability of the issuers of the securities held by the Series to meet their
obligations may be affected by economic developments in a specific state,
industry or region.
                              
Note 1. Accounting            The following is a summary
Policies                      of significant accounting poli-
                              cies followed by the Fund, and the Series, in the
preparation of its financial statements.
Securities Valuations: The Series values municipal securities (including
commitments to purchase such securities on a ``when-issued'' basis) on the basis
of prices provided by a pricing service which uses information with respect to
transactions in bonds, quotations from bond dealers, market transactions in
comparable securities and various relationships between securities in
determining values. If market quotations are not readily available from such
pricing service, a security is valued at its fair value as determined under
procedures established by the Trustees.
   Short-term securities which mature in more than 60 days are valued at current
market quotations. Short-term securities which mature in 60 days or less are
valued at amortized cost.
   All securities are valued as of 4:15 P.M., New York time.
Financial Futures Contracts: A financial futures contract is an agreement to
purchase (long) or sell (short) an agreed amount of debt securities at a set
price for delivery on a future date. Upon entering into a financial futures
contract, the Series is required to pledge to the broker an amount of cash
and/or other assets equal to a certain percentage of the contract amount. This
amount is known as the ``initial margin''. Subsequent payments, known as
``variation margin'', are made or received by the Series each day, depending on
the daily fluctuations in the value of the underlying security. Such variation
margin is recorded for financial statement purposes on a daily basis as
unrealized gain or loss. The Series invests in financial futures contracts
solely for the purpose of hedging its existing portfolio securities or
securities the Series intends to purchase against fluctuations in value caused
by changes in prevailing market interest rates. Should interest rates move
unexpectedly, the Series may not achieve the anticipated benefits of the
financial futures contracts and may realize a loss. The use of futures
transactions involves the risk of imperfect correlation in movements in the
price of futures contracts, interest rates and the underlying hedged assets.
Securities Transactions and Investment Income: Securities transactions are
recorded on the trade date. Realized gains and losses on sales of securities are
calculated on the identified cost basis. Interest income is recorded on the
accrual basis. The Series amortizes premiums and original issue discount paid on
purchases of portfolio securities as adjustments to interest income.
   Net investment income (other than distribution fees) and unrealized and
realized gains or losses are allocated daily to each class of shares based upon
the relative proportion of net assets of each class at the beginning of the day.
Federal Income Taxes: For federal income tax purposes, each series in the Fund
is treated as a separate taxpaying entity. It is the intent of the Series to
continue to meet the requirements of the Internal Revenue Code applicable to
regulated investment companies and to distribute all of its net income to
shareholders. For this reason and because substantially all of the Series' gross
income consists of tax-exempt interest, no federal income tax provision is
required.
Dividends and Distributions: The Series declares daily dividends from net
investment income. Payment of dividends is made monthly. Distributions of net
capital gains, if any, are made annually.
   Income distributions and capital gain distributions are determined in
accordance with income tax regulations which may differ from generally accepted
accounting principles.
                                      -11-
 <PAGE>
<PAGE>
                              
Note 2. Agreements            The Fund has a management
                              agreement with Prudential Mutual Fund Management,
Inc. (``PMF''). Pursuant to this agreement PMF has responsibility for all
investment advisory services and supervises the subadviser's performance of such
services. PMF has entered into a subadvisory agreement with The Prudential
Investment Corporation (``PIC''); PIC furnishes investment advisory services in
connection with the management of the Fund. PMF pays for the cost of the
subadviser's services, the compensation of officers of the Fund, occupancy and
certain clerical and bookkeeping costs of the Fund. The Fund bears all other
costs and expenses.
   The management fee paid PMF is computed daily and payable monthly, at an
annual rate of .50 of 1% of the average daily net assets of the Series.
   The Fund has distribution agreements with Prudential Mutual Fund
Distributors, Inc. (``PMFD''), which acts as the distributor of the Class A
shares of the Fund, and with Prudential Securities Incorporated (``PSI''), which
acts as distributor of the Class B and Class C shares of the Fund (collectively
the ``Distributors''). The Fund compensates the Distributors for distributing
and servicing the Fund's Class A, Class B and Class C shares, pursuant to plans
of distribution, (the ``Class A, B and C Plans'') regardless of expenses
actually incurred by them. The distribution fees are accrued daily and payable
monthly.
   On July 19, 1994, shareholders of the Fund approved amendments to the Class A
and Class B distribution plans under which the distribution plans became
compensation plans, effective August 1, 1994. Prior thereto, the distribution
plans were reimbursement plans, under which PMFD and PSI were reimbursed for
expenses actually incurred by them up to the amount permitted under the Class A
and Class B Plans, respectively. The Fund is not obligated to pay any prior or
future excess distribution costs (costs incurred by the Distributors in excess
of distribution fees paid by the Fund or contingent deferred sales charges
received by the Distributors). The rate of the distribution fees charged to
Class A and Class B shares of the Fund did not change under the amended plans of
distribution. The Fund began offering Class C shares on August 1, 1994.
   Pursuant to the Class A, B and C Plans, the Fund compensates the Distributors
for distribution-related activities at an annual rate of up to .30 of 1%, .50 of
1% and 1%, of the average daily net assets of the Class A, B and C shares,
respectively. Such expenses under the Plans were .10 of 1%, .50 of 1% and .75 of
1% of the average daily net assets of the Class A, B and C shares, respectively,
for the fiscal year ended August 31, 1994.
   PMFD has advised the Series that it has received approximately $72,700 in
front-end sales charges resulting from sales of Class A shares during the fiscal
year ended August 31, 1994. From these fees, PMFD paid such sales charges to PSI
and Pruco Securities Corporation, affiliated broker-dealers, which in turn paid
commissions to salespersons and incurred other distribution costs.
   PSI has advised the Series that for the fiscal year ended August 31, 1994, it
received approximately $96,400 in contingent deferred sales charges imposed upon
certain redemptions by Class B shareholders.
   PMFD is a wholly-owned subsidiary of PMF; PSI, PMF and PIC are indirect,
wholly-owned subsidiaries of The Prudential Insurance Company of America.
                              
Note 3. Other                 Prudential Mutual Fund Ser-
Transactions                  vices, Inc. (``PMFS''), a 
With Affiliates               wholly-owned subsidiary of 
                              PMF, serves as the Fund's transfer agent. During
the year ended August 31, 1994 the Series incurred fees of approximately $53,000
for the services of PMFS. As of August 31, 1994, approximately $4,000 of such
fees were due to PMFS. Transfer agent fees and expenses in the Statement of
Operations include certain out-of-pocket expenses paid to non-affiliates.
                              
Note 4. Portfolio             Purchases and sales of port-
Securities                    folio securities of the Series, 
                              excluding short-term investments, for the year
ended August 31, 1994 were $30,071,941 and $25,048,220, respectively.
   The cost basis of investments for federal income tax purposes at August 31,
1994 was substantially the same as for financial reporting purposes and,
accordingly, net unrealized appreciation of investments, including short-term
investments, for federal income tax purposes was $5,753,740 (gross unrealized
appreciation--$7,676,486; gross unrealized depreciation--$1,922,746).
   For federal income tax purposes, the Series has a capital loss carryforward
as of August 31, 1994 of approximately $279,400 which expires in 1996. Such
carryforward is after utilization of approximately $772,000 to offset the
Series' net taxable gains recognized in the year ended August 31, 1994.
Accordingly, no capital gains distributions are expected to be paid to
shareholders until net gains have been realized in excess of such carryforward.
   At August 31, 1994 the Series sold 58 financial futures contracts on U.S.
Treasury Bonds which expire in September 1994. The value at disposition of such
contracts is $5,973,188. The value of such contracts on August 31,
                                      -12-
 <PAGE>
<PAGE>
1994 was $6,015,688, thereby resulting in an unrealized loss of $42,500.
                              
Note 5. Capital               The Series currently offers
                              Class A, Class B and Class C shares. Class A
shares are sold with a front-end sales charge of up to 3.0%. Class B shares are
sold with a contingent deferred sales charge which declines from 5% to zero
depending on the period of time the shares are held. Class C shares are sold
with a contingent deferred sales charge of 1% during the first year. Class B
shares will automatically convert to Class A shares on a quarterly basis
approximately seven years after purchase commencing in or about February 1995.
   The Fund has authorized an unlimited number of shares of beneficial interest
of each class at $.01 par value per share.
   Transactions in shares of beneficial interest for the fiscal years ended
August 31, 1994 and 1993 were as follows:
<TABLE>
<CAPTION>
Class A                            Shares         Amount
- ------------------------------   ----------    ------------
<S>                              <C>           <C>
Year ended August 31, 1994:
Shares sold...................      163,929    $  1,993,081
Shares issued in reinvestment
  of dividends................       12,343         148,632
Shares reacquired.............     (146,584)     (1,788,120)
                                 ----------    ------------
Net increase in shares
  outstanding.................       29,688    $    353,593
                                 ----------    ------------
                                 ----------    ------------
Year ended August 31, 1993:
Shares sold...................      237,725    $  2,875,262
Shares issued in reinvestment
  of dividends................        9,080         108,980
Shares reacquired.............      (50,464)       (609,662)
                                 ----------    ------------
Net increase in shares
  outstanding.................      196,341    $  2,374,580
                                 ----------    ------------
                                 ----------    ------------
</TABLE>
<TABLE>
<CAPTION>
Class B                            Shares         Amount
- ------------------------------   ----------    ------------
<S>                              <C>           <C>
Year ended August 31, 1994:
Shares sold...................    1,210,935    $ 14,657,554
Shares issued in reinvestment
  of dividends................      295,981       3,564,474
Shares reacquired.............   (1,270,756)    (15,198,847)
                                 ----------    ------------
Net increase in shares
  outstanding.................      236,160    $  3,023,181
                                 ----------    ------------
                                 ----------    ------------
Year ended August 31, 1993:
Shares sold...................    1,561,093    $ 18,690,303
Shares issued in reinvestment
  of dividends................      282,692       3,382,260
Shares reacquired.............     (731,090)     (8,690,391)
                                 ----------    ------------
Net increase in shares
  outstanding.................    1,112,695    $ 13,382,172
                                 ----------    ------------
                                 ----------    ------------
 
<CAPTION>
Class C
- ------------------------------
<S>                              <C>           <C>
August 1, 1994* through
  August 31, 1994:
Shares sold...................          446    $      5,200
                                 ----------    ------------
                                 ----------    ------------
- ---------------
* Commencement of offering of Class C shares.
</TABLE>
                                      -13-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 OHIO SERIES
 Financial Highlights
<TABLE>
<CAPTION>
                                Class A                                                                                 Class C
         ------------------------------------------------------                        Class B                         ----------
                                                   January 22,    --------------------------------------------------   August 1,
                                                     1990(D)                                                           1994(D)(D)
                  Year Ended August 31,              Through                    Year Ended August 31,                   Through
         ---------------------------------------    August 31,    --------------------------------------------------   August 31,
             1994        1993     1992     1991        1990         1994       1993       1992      1991      1990        1994
            ------      ------   ------   ------      ------      --------   --------   --------   -------   -------   ----------
<S>      <C>            <C>      <C>      <C>      <C>            <C>        <C>        <C>        <C>       <C>       <C>
PER
  SHARE
  OPERATING
  PERFORMANCE:
Net
  asset
 value,
  beginning
  of
  period...    $12.38   $11.69   $11.17   $10.71      $10.85      $  12.38   $  11.70   $  11.18   $ 10.71   $ 10.85     $11.75
            ------      ------   ------   ------      ------      --------   --------   --------   -------   -------   ----------
Income
  from
  investment
  operations
Net
investment
 income...       .66       .69      .70      .70         .47           .61        .65        .65       .65       .66        .05
Net
realized
  and
  unrealized
  gain
 (loss)
  on
  investment
  trans-
  actions...  (.66)        .69      .52      .46        (.14)         (.65)       .68        .52       .47      (.14)      (.02)
            ------      ------   ------   ------      ------      --------   --------   --------   -------   -------   ----------
  Total
   from
   investment
    oper-
    ations.     --        1.38     1.22     1.16         .33          (.04)      1.33       1.17      1.12       .52        .03
Less
dividends
Dividends
  from
  net
  investment
  income...   (.66)       (.69)    (.70)    (.70)       (.47)         (.61)      (.65)      (.65)     (.65)     (.66)      (.05)
            ------      ------   ------   ------      ------      --------   --------   --------   -------   -------   ----------
Net
  asset
 value,
  end
  of
  period    $11.72      $12.38   $11.69   $11.17      $10.71      $  11.73   $  12.38   $  11.70   $ 11.18   $ 10.71     $11.73
            ------      ------   ------   ------      ------      --------   --------   --------   -------   -------   ----------
            ------      ------   ------   ------      ------      --------   --------   --------   -------   -------   ----------
TOTAL
RETURN#:...  (0.01)%     12.12%   11.26%   11.06%       2.58%        (0.33)%    11.58%     10.79%    10.74%     4.87%      0.18%
RATIOS/SUPPLEMENTAL
  DATA:
Net
assets,
  end
  of
 period
(000)..     $4,749      $4,647   $2,095    $ 923      $  462      $118,270   $121,937   $102,199   $92,572   $89,183     $5,227@
Average
  net
 assets
 (000)...   $4,733      $2,904   $1,289    $ 615      $  289      $121,365   $110,053   $ 96,178   $90,437   $89,302     $1,752@
Ratios
  to
average
  net
  assets:##
  Expenses,
  including
    distri-
    bution
    fees...    .84%        .84%     .81%     .93%        .96%*        1.24%      1.24%      1.21%     1.33%     1.32%      2.28%*
  Expenses,
  excluding
    distri-
    bution
    fees...    .74%        .74%     .71%     .83%        .86%*         .74%       .74%       .71%      .83%      .84%      1.53%*
  Net
  investment
  income...   5.45%       5.73%    6.34%    6.34%       6.51%*        5.05%      5.33%      5.73%     5.94%     6.08%      4.73%*
Portfolio
turnover...     20%         28%      37%      37%         24%           20%        28%        37%       37%       24%        20%

 
- ---------------
   * Annualized.
 (D) Commencement of offering of Class A shares.
(D)(D) Commencement of offering of Class C shares.
   # Total return does not consider the effects of sales loads. Total return is calculated assuming a purchase
     of shares on the first day and a sale on the last day of each period reported and includes reinvestment of
     dividends and distributions. Total return for periods of less than one full year are not annualized.
  ## Because of the events referred to in (D)(D) and the timing of such, the ratios for the Class C shares are
     not necessarily comparable to that of Class A or B shares and are not necessarily indicative of future
     ratios.
   @ Figures are actual and are not rounded to the nearest thousand.

</TABLE>
See Notes to Financial Statements.
                                      -14-
 <PAGE>
<PAGE>
                          INDEPENDENT AUDITORS' REPORT
The Shareholders and Board of Trustees
Prudential Municipal Series Fund, Ohio Series
   We have audited the accompanying statement of assets and liabilities of
Prudential Municipal Series Fund, Ohio Series, including the portfolio of
investments, as of August 31, 1994, the related statements of operations for the
year then ended and of changes in net assets for each of the two years in the
period then ended, and the financial highlights for each of the five years in
the period then ended. These financial statements and financial highlights are
the responsibility of the Fund's management. Our responsibility is to express an
opinion on these financial statements and financial highlights based on our
audits.
   We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements and financial
highlights are free of material misstatement. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements. Our procedures included confirmation of the securities owned as of
August 31, 1994 by correspondence with the custodian and brokers; where replies
were not received from brokers, we performed other auditing procedures. An audit
also includes assessing the accounting principles used and significant estimates
made by management, as well as evaluating the overall financial statement
presentation. We believe that our audits provide a reasonable basis for our
opinion.
   In our opinion, such financial statements and financial highlights present
fairly, in all material respects, the financial position of Prudential Municipal
Series Fund, Ohio Series, as of August 31, 1994, the results of its operations,
the changes in its net assets, and its financial highlights for the respective
stated periods in conformity with generally accepted accounting principles.
Deloitte & Touche LLP
New York, New York
October 17, 1994
                         FEDERAL INCOME TAX INFORMATION
   We are required by the Internal Revenue Code to advise you within 60 days of
the Series' fiscal year end (August 31, 1994) as to the federal tax status of
dividends paid by the Series during such fiscal year. Accordingly, we are
advising you that in the fiscal year ended August 31, 1994, dividends paid from
net investment income of $.66 per Class A share, $.61 per Class B share and $.05
per Class C share were all federally tax-exempt interest dividends.
   In January 1995, you will be advised on IRS Form 1099 DIV or substitute 1099
DIV as to the federal tax status of the dividends received by you in calendar
year 1994.
                                      -15-
 <PAGE>
<PAGE>
   These graphs are furnished to you in accordance with SEC regulations. They
compare a $10,000 investment in Prudential Municipal Series Fund: Ohio Series
(Class A, Class B, and Class C) with a similar investment in the Lehman Brothers
Municipal Bond Index (the Index) by portraying the initial account values at the
commencement of operations of each class and subsequent account values at the
end of each fiscal year (August 31) beginning in 1990 for Class A, in 1984 for
Class B shares and 1994 for Class C shares. For purposes of the graphs and,
unless otherwise indicated, the accompanying tables, it has been assumed that
(a) the maximum sales charge was deducted from the initial $10,000 investment in
Class A shares; (b) the maximum applicable contingent deferred sales charge was
deducted from the value of the investment in Class B shares and Class C shares,
assuming full redemption on August 31, 1994; (c) all recurring fees (including
management fees) were deducted; and (d) all dividends and distributions were
reinvested. Class B shares will automatically convert to Class A shares on a
quarterly basis approximately seven years after purchase. This conversion
feature is expected to be implemented on or about February 1995 and is not
reflected in the graph. The graph and accompanying tables reflect the past
subsidy and/or waiver of expenses and/or management fees. Without fee waivers
and expense subsidies, the value of a $10,000 investment in the Series and the
Series' average annual total return, as shown above, would have been lower.
   The Index is a weighted index comprised of 21,000 municipal bonds (general
obligation bonds, revenue bonds, insured bonds and prerefunded bonds) selected
by Lehman Brothers as representative of the long-term investment grade municipal
bond market. The Index is an unmanaged index and includes the reinvestment of
all income, but does not reflect the payment of transaction costs and advisory
fees associated with an investment in the Series. The securities which comprise
the Index may differ substantially from the securities in the Series' portfolio
because the Index, among other things, is not state specific. The Lehman
Brothers Municipal Bond Index is not the only index which may be used to
characterize performance of long-term, investment-grade tax-exempt bond funds
and other indexes may portray different comparative performance.
                                      -16-
 <PAGE>































































ANNUAL REPORT                           August 31, 1994

Prudential
Municipal
Series Fund

(ICON)

Pennsylvania Series

(LOGO)

<PAGE>
Letter to Shareholders

October 18, 1994 

Dear Shareholder:

It has been a most difficult year in the U.S. financial markets.  When we 
last wrote in February interest rates were starting to rise, ending a 
three-year long bull market in bonds. What started as a trickle has 
become a torrent.  Interest rates have continued to increase this year, 
sending bond prices down sharply.  Of course, as interest rates rise, 
bond prices decline.  In this environment of falling prices and unusual 
volatility, your Prudential Municipal Series Fund -- Pennsylvania Series 
sought to minimize risk while maximizing your tax-free income.

The Series seeks maximum income exempt from Pennsylvania and federal 
income taxes* consistent with preservation of capital.  The Series 
is comprised of investment grade municipal obligations with an average 
Aa/AA credit quality as determined by Moody's Investors Service or 
Standard & Poor's Ratings Group.  The Series performed in line with 
the Lipper Pennsylvania Municipal Debt Average over the last year, 
but because long-term interest rates rose, total returns were 
disappointing.  As a result, the Series has become more cautious 
and shortened its average maturity.

<TABLE>
                          SERIES PERFORMANCE 
                         As of August 31, 1994
<CAPTION>
                   30-day            Taxable Equivalent Yields  
          NAV    SEC Yield         @28%        @31%       @39.6%
<S>      <C>        <C>            <C>         <C>         <C>
Class A  $10.42     5.0%           7.2%        7.5%        8.6%
Class B  $10.42     4.8%           6.8%        7.1%        8.2% 
Class C  $10.42     N/A            N/A         N/A         N/A
</TABLE>

Investment return and principal value will fluctuate so that an 
investor's shares, when redeemed, may be worth more or less than 
their original cost.  Past performance is no guarantee of future results.

*Interest on municipal obligations may be subject to the federal 
alternative minimum tax. See your Series' prospectus for more 
details.

N/A = Yield information with respect to Class C is not available 
as operations commenced in August 1994.

                             -1-

<PAGE>
<TABLE>
                                    TOTAL RETURNS
<CAPTION>
                     Historical (As of 8/31/94)1       Average Annual (As of 9/30/94)2
                    1-Yr.     5-Yr.  Since Incep.**   1-Yr.      5-Yr.  Since Incep.**
<S>                 <C>       <C>       <C>           <C>       <C>        <C>   
Class A             -0.8%      N/A      +41.1%        -6.5%      N/A       +6.5%
Class B             -1.2%    +43.0%     +66.1%        -9.0%     +7.0%      +6.7%
Class C              N/A       N/A       +0.1%         N/A       N/A       -2.5%
Lipper PA 
Muni Debt Avg.***   -1.0%    +47.0%     +66.7%         N/A       N/A        N/A  
</TABLE>

1 Source: Lipper Analytical Services, Inc. These figures do not take into 
account sales charges.

2 Source: Prudential Mutual Fund Management, Inc.  These averages 
take into account applicable sales charges.  The Series charges a 
maximum initial sales charge of 3% for Class A shares.  Class B 
shares are subject to a declining contingent deferred sales charge 
of 5%, 4%, 3%, 2%, 1% and 1%, respectively, for the first six years.  
Class B shares will automatically convert to Class A shares approximately 
seven years after purchase.  This conversion feature is expected to be 
implemented in February 1995. Class C shares are subject to contingent 
deferred sales charge of 1% during the first year. 

**Inception on January 22, 1990 for Class A, and April 3, 1987 for Class 
B and August 1, 1994 for Class C.

***These are the average returns of 50 Pennsylvania municipal debt funds 
for one-year, five-year, and since inception of Class B shares, as 
determined by Lipper Analytical Services, Inc. 

Note:  Without expense subsidies and management fee waivers, the Series' 
historical and average annual total returns would have been lower.  The 
Series' Class B average annual total return since inception would have 
been 6.6%.

Once Was Not Enough

When we wrote to you in February, the Federal Reserve raised short-term 
interest rates for the first time in years, hoping to control inflation.  
Since then, the Fed has moved four more times, until the federal funds 
rate (the overnight interbank lending rate) now stands at 4.75%, up 
from 3% at the start of the year.  The Fed also increased the discount 
rate (at which it lends banks money) to 4% from 3% over the same period.

Interest rates rise when the financial markets fear inflation, the bond 
holder's enemy. Inflation is feared because it robs purchasing power from 
a bond's fixed-interest rate.

Municipal bond interest rates increased by nearly a percentage point, to 
6.46% on August 25 from 5.52% on December 29, 1993, as measured by the 
Bond Buyer's Revenue Bond Index, a widely used yardstick of interest rates 
in the tax-free market.

Pennsylvania:  Government Wants Growth

The highest corporate income tax in the nation and a heavy reliance on 
manufacturing for employment have resulted in slow economic growth for 
Pennsylvania.  But state government is working to turn the situation around.

                                      -2-

<PAGE>
By increasing taxes and cutting expenditures, the state eliminated its 
accumulated deficit in 1993, replacing it with a surplus to which it 
added $302 million in fiscal 1994.  On the spending side, the state is 
building five new 1,000-bed prisons and as a result, corrections 
operating expenses will increase by 20%.  In addition, the state 
plans to issue $474 million in general obligation bonds this year.

There is a bipartisan consensus to lower tax rates to attract new 
business, so some sort of action is expected to adjust the extremely 
high business and corporate income taxes this year.

Supply of new bonds in Pennsylvania is down 43% year-to-date from last 
year.  We reduced exposure to the health care sector, because we are not 
being compensated in yield given the increased uncertainty in the 
industry.  We  added university sector holdings because they offer 
good value in a more stable environment.

A Tax Reminder

As a result of the federal Revenue Reconciliation Act of 1993, which 
affects bonds purchased after April 30, 1993,  it is possible that 
this year you may have some taxable income from your tax-free municipal 
bond fund.  The law stipulates that the portion of any gain realized on 
the sale or retirement of a tax-free bond purchased at a market discount 
to its face value must be taxed as ordinary income.

As a result of this change in federal tax law, some discount bonds have 
been selling at levels so cheap they will produce a higher after-tax 
return than other bonds not subject to the provisions of the new law.  
We have occasionally taken advantage of this market imbalance because 
we have determined that at very low prices these bonds can still 
provide you with a higher after-tax return on your investment.

The Outlook

We expect volatility in the municipal bond market until the economy 
reaches a level of growth that is sustainable without causing inflation.  
If the economy continues to surge, the ever vigilant Fed will move once 
again, boosting short-term rates.  If the economy slows substantially, 
long term rates should stabilize.  Although rates may keep rising, we 
believe that most of the increase is now behind us.

In the months ahead, we expect supply -- or the lack of it -- to become 
more important in the tax-free municipal bond market.  Through the first 
eight months of the year, new issue volume is off 42%, according to 
Securities Data Co., which tracks this statistic.  The pace is 
accelerating.  In August, new issue volume fell 56%.  

                                   -3-

<PAGE>

As always, it is a pleasure to have you as a shareholder in the 
Prudential Municipal Series Fund -- Pennsylvania Series, and to 
take this opportunity to report our activities to you.

Sincerely,

Lawrence C. McQuade
President

Carla A. Wrocklage
Portfolio Manager

                                     -4-
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                      Portfolio of Investments
PENNSYLVANIA SERIES                                            August 31, 1994
<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                  Value            
(Unaudited)     (000)          Description(a)         (Note 1)       
<C>           <C>          <S>                      <C>
                           LONG-TERM INVESTMENTS--97.0%
                           Allegheny Cnty. Arpt.
                             Rev.,
                           Greater Pittsburgh
                             Int'l. Arpt.,
                             F.S.A.,
                           6.60%, 1/1/04, Ser.
Aaa            $  1,000      A....................  $  1,081,510
Aaa               1,230    5.625%, 1/1/23.........     1,113,322
                           Allegheny Cnty., Gen.
                             Oblig., M.B.I.A.,
                           7.30%, 12/1/10, Ser.
Aaa               1,500(D)   C-37.................     1,685,625
                           Allegheny Cnty. Higher
                             Ed. Bldg.
                             Auth. Rev., Robert
                             Morris Coll.,
                           7.00%, 6/15/08,
Aaa               1,000      M.B.I.A..............     1,068,280
                           Allegheny Cnty. Hosp.
                             Dev. Auth.
                             Rev., Magee Womens
                             Hosp., F.G.I.C.,
Aaa               2,000    Zero Coupon, 10/1/14...       566,560
Aaa               2,000    Zero Coupon, 10/1/16...       496,480
Aaa               2,000    Zero Coupon, 10/1/18...       433,540
Aaa               4,000    Zero Coupon, 10/1/19...       809,840
                           Presbyterian Univ.
                             Hosp.,
                           7.625%, 7/1/15, Ser. C,
Aaa               1,100      M.B.I.A..............     1,217,282
                           West Penn. Hosp. Hlth.
                             Ctr. Proj.,
NR                2,000    8.50%, 1/1/20..........     2,249,240
                           Allegheny Cnty.
                             Pennsylvania
                             Ind. Dev. Rev. USX
                             Proj.,
Baa3              4,500    6.70%, 12/1/20.........     4,502,925
                           Allegheny Cnty.
                             Residential Fin.
                             Auth.,
                           Mtge. Rev., G.N.M.A.,
                           9.00%, 6/1/17, Ser.
Aaa                 460      F....................       491,110
                           7.40%, 12/1/22, Ser.
Aaa                 970      Q....................     1,003,872
                           Allegheny Cnty. San.
                             Auth. Swr. Rev.,
                             F.G.I.C.,
Aaa               2,620    Zero Coupon, 12/1/05...     1,399,840
                           Zero Coupon, 6/1/06,
Aaa               1,640      Ser. A...............       839,598
                           Beaver Cnty. Ind. Dev.
                             Auth. Poll. Ctrl.
                             Rev.,
                           Ohio Edison Proj.,
                           7.75%, 9/1/24, Ser. A,
Aaa               1,150      F.G.I.C..............     1,292,738
                           Berks Cnty. Ind. Dev.
                             Auth. Rev.,
                           Lutheran Home Proj.,
NR             $  1,500    6.875%, 1/1/23.........  $  1,462,410
                           Bethlehem Auth. Wtr.
                             Rev.,
                           5.20%, 11/15/21,
Aaa               3,000      M.B.I.A..............     2,586,660
                           Bristol Twnshp. Sch.
                             Dist.,
                           Gen Oblig., M.B.I.A.,
                           6.625%, 2/15/12, Ser.
Aaa               1,500      A....................     1,651,125
                           Bucks Cnty. Wtr. & Swr.
                             Auth. Rev.,
                           Neshaminy Interceptor
                             Sys.,
                           7.50%, 12/1/13,
Aaa               2,000(D)   F.G.I.C..............     2,213,260
                           Butler Cnty. Hosp.
                             Auth. Rev.,
                           North Hills, Passavant
                             Hosp.,
                           7.00%, 6/1/22,
AAA*              1,000      C.G.I.C..............     1,059,490
                           Cambria Cnty.
                             Pennsylvania
                           Ser. A, F.G.I.G.,
Aaa               2,000    6.20%, 8/15/21.........     1,999,920
                           Chester Upland Sch.
                             Auth.,
                           6.375%, 9/1/21, Ser.
A*                1,000      A....................     1,000,910
                           Dauphin Cnty. Gen.
                             Auth. Rev.,
Aaa               1,000    7.40%, 1/1/06, B.I.G...     1,076,190
                           Delaware Cnty. Auth.
                             Rev.,
                           Crozer Chester Med.
                             Ctr., M.B.I.A.,
                           7.15%, 12/15/05, Ser.
Aaa               2,550      ABC..................     2,882,775
                           Villanova Univ.,
NR                1,000(D) 7.75%, 8/1/18..........     1,122,270
                           Delaware Cnty. Ind.
                             Dev. Auth. Rev., Res.
                             Recovery Proj.,
                           8.10%, 12/1/13, Ser.
A1                2,000      A....................     2,125,100
                           Delaware Cnty.
                             Pennsylvania Auth.
                             Univ. Rev.,
                           Villanova Univ.,
                           5.50%, 8/1/23,
Aaa               3,000      M.B.I.A..............     2,707,920
                           Delaware River Jt. Toll
                             Bridge Comm. Rev.,
                           6.00%, 7/1/18,
Aaa               5,500      F.G.I.C..............     5,464,965
</TABLE>
 
                                      -5-     See Notes to Financial Statements.
<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                      
PENNSYLVANIA SERIES                                            
<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                  Value            
(Unaudited)     (000)          Description(a)         (Note 1)       
<C>           <C>          <S>                      <C>
                           Doylestown Hosp. Auth.
                             Rev.,
                           Pine Run Retirement,
                           7.20%, 7/1/23, Ser.
NR             $  1,180      A....................  $  1,222,020
                           Emmaus Gen. Auth. Rev.,
                           Local Gov't. Bond,
                             B.I.G.,
                           8.00%, 5/15/18, Ser.
Aaa               1,000      B....................     1,100,590
                           7.90%, 5/15/18, Ser.
Aaa               1,250      C....................     1,383,250
                           7.90%, 5/15/18, Ser.
Aaa               2,000      E....................     2,213,200
                           7.90%, 5/15/18, Ser.
Aaa               1,600      F....................     1,770,560
                           Erie Higher Ed. Bldg.
                             Auth. Coll. Rev.,
                           Mercyhurst Coll. Proj.,
BBB*              1,000(D) 7.85%, 9/15/19.........     1,130,280
                           5.75%, 3/15/23, Ser.
BBB*              3,250      B....................     2,908,360
                           Falls Twnshp. Hosp.
                             Auth. Rev.,
                           Delaware Valley Med.,
                           7.00%, 8/1/22,
AAA*              2,700      F.H.A................     2,870,343
                           Guam Arpt. Auth. Rev.,
                           6.70%, 10/1/23, Ser.
BBB*              3,500      B....................     3,520,090
                           Harrisburg Auth. Rev.,
                           Green Cnty. Prison
                             Proj.,
                           6.625%, 6/1/13,
Aaa               1,500      F.G.I.C..............     1,618,365
                           Harrisburg Redev. Auth.
                             Rev.,
                           Cap. Impvt.,
                           7.875%, 11/2/16, Ser.
Aaa                 900      A, F.G.I.C...........       972,000
                           Lancaster Cnty. Solid
                             Waste
                             Mgmt. Auth., Rev.,
                             Res. Rec. Sys.
A1                  500    7.875%, 12/15/09.......       508,345
                           Res. Rec. Sys.
                             Landfill,
A1                  750    7.75%, 12/15/04........       774,120
                           Langhorne Manor Boro.
                             Higher Ed. & Hlth.
                             Auth Rev.,
                             Lower Bucks Hosp.,
Baa               3,275    7.35%, 7/1/22..........     3,373,774
                           Latrobe Pennsylvania
                             Ind. Dev. Auth. Coll.
                             Rev.,
                           St Vincents Coll.
                             Proj.,
Baa1              1,800    6.75%, 5/1/14..........     1,804,086
                           St. Vincent Coll.
                             Proj.,
Baa1           $  1,500    6.75%, 5/1/24..........  $  1,486,500
                           Lehigh Cnty. Gen.
                             Purpose Auth.
                             Revs., Horizon Hlth.
                             Sys. Inc.,
                           8.25%, 7/1/13, Ser.
NR                  500      A....................       635,810
                           8.25%, 7/1/13, Ser.
A+*                 750(D)   B....................       826,148
                           St. Lukes Hosp. of
                             Bethlehem Proj.,
                           5.30%, 11/15/06,
Aaa                 750      A.M.B.A.C............       724,433
                           5.30%, 11/15/07,
Aaa               1,000      A.M.B.A.C............       954,210
                           Lehigh Cnty. Ind. Dev.
                             Auth. Poll.
                             Ctrl. Rev.,
                           Pa. Pwr. & Lt. Co.,
                           9.375%, 7/1/15, Ser.
A2                1,300      A....................     1,379,157
                           Luzerne Cnty. Ind. Dev.
                             Auth.
                           Exmpt. Facs. Rev., Gas
                             & Water,
Baa3              4,000    7.20%, 10/1/17.........     4,051,040
                           7.125%, 12/1/22, Ser.
Baa3              2,000      B....................     2,027,940
                           Montgomery Cnty. Higher
                             Ed. & Hlth. Auth.
                             Hosp. Rev.,
                           Jeanes Hlth. Sys.
                             Proj.,
BBB*              4,000(D) 8.625%, 7/1/07.........     4,783,080
                           Montgomery Cnty. Ind.
                             Dev. Auth. Rev.,
                             Poll. Ctrl.,
                           Philadelphia Elec.,
Baa2              1,000    7.60%, 4/1/21..........     1,040,740
                           Res. Recovery,
AA-*              2,000    7.50%, 1/1/12..........     2,098,020
                           Montgomery Cnty. Redev.
                             Auth.,
                           Multi-family Hsg.,
                           6.50%, 7/1/25, Ser.
NR                3,000      A....................     2,861,850
                           No. Huntingdon Twnshp.
                             Mun. Auth.,
                           Gtd. Swr. Rev.,
                           6.70%, 4/1/06,
Aaa               1,070      M.B.I.A..............     1,133,376
                           Northampton Cnty.
                             Higher Ed.
                             Auth. Rev., Lehigh
                             Univ.,
                           7.10%, 11/15/09,
Aaa               1,500      M.B.I.A..............     1,646,970
</TABLE>
 
                                      -6-     See Notes to Financial Statements.

<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                      
PENNSYLVANIA SERIES                                            
<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                  Value            
(Unaudited)     (000)          Description(a)         (Note 1)       
<C>           <C>          <S>                      <C>
                           Northampton Cnty.
                             Higher Ed.
                             Auth. Rev.,
                             Moravian Coll.,
BBB-*          $  2,095    8.20%, 6/1/11..........  $  2,375,541
                           Northampton Cnty. Ind.
                             Dev.
                             Auth. Rev., Citizens
                             Util. Co.,
AAA*              1,000    6.95%, 8/1/15..........     1,044,570
                           Northeastern Hosp. &
                             Ed. Auth.
                             Coll. Rev.,
BBB*              1,500    6.00%, 7/15/18.........     1,406,070
                           Northumberland Cnty.
                             Ind. Dev.
                             Auth. Rev., Roaring
                             Creek Wtr.,
NR                1,500    6.375%, 10/15/23.......     1,361,640
                           Pennsylvania Hsg. Fin.
                             Agcy.,
                           Sngl. Fam. Mtge. Rev.,
Aa                1,050(D)(D) 8.769%, 4/1/25.........      918,750
                           Sngl. Fam. Mtge.,
                           8.10%, 10/1/10, Ser.
Aa                  780      X....................       810,030
                           7.60%, 4/1/16, Ser.
Aa                1,000      S....................     1,059,230
Aa                2,930    7.80%, 10/1/20.........     3,072,544
                           8.15%, 4/1/24, Ser.
Aa                1,280      X....................     1,331,341
                           Pennsylvania Ind. Auth.
                             Econ. Dev. Rev.,
                           7.00%, 1/1/11, Ser.
A                 3,000(D)   A....................     3,362,100
                           Pennsylvania
                             Infrastructure
                             Investment Auth.
                             Rev.,
AA*                 750    6.80%, 9/1/10..........       791,160
                           Pennsylvania
                             Intergovernmental
                             Cooperation Auth.,
                           Spec.Tax Rev.,
                           5.60%, 6/15/15,
Aaa               4,000      M.B.I.A..............     3,703,640
Baa               1,000(D) 6.80%, 6/15/22.........     1,101,300
                           Pennsylvania St. Gen.
                             Oblig., F.S.A.,
                           6.25%, 11/1/06, Ser.
Aaa               4,000      A....................     4,160,720
                           Pennsylvania St. Higher
                             Edl. Facs. Auth.
                             Rev.,
                           Coll. & Univ. Rev.,
                           6.00%, 11/1/22, Ser.
BBB+*             2,000      B....................     1,821,100
                           Drexel Univ.,
BBB*           $  2,500    6.375%, 5/1/17.........  $  2,416,925
                           Hahnemann Univ. Proj.,
                           7.20%, 7/1/09,
Aaa               1,500      M.B.I.A..............     1,652,730
                           La Salle Univ.,
                           7.70%, 5/1/10,
Aaa               1,100      M.B.I.A..............     1,224,465
                           Med. Coll. of
                             Pennsylvania,
                           8.375%, 3/1/11, Ser.
Baa1                355      A....................       387,387
                           7.50%, 3/1/14, Ser.
Baa1              2,350      A....................     2,432,767
                           St. Sys. Ser. J,
                           5.625%, 6/15/19,
Aaa               1,520      A.M.B.A.C............     1,393,749
                           Thomas Jefferson Univ.,
                           6.625%, 8/15/09, Ser.
Aa                1,000      A....................     1,052,420
                           8.00%, 1/1/18, Ser.
AAA*              1,250(D)   A,...................     1,394,312
                           Pennsylvania St. Ind.
                             Dev. Auth. Rev.,
                             Econ. Dev.,
Aaa               4,250    5.50%, 1/1/14..........     3,908,172
                           Pennsylvania St. Tpke.
                             Comn. Rev.,
                           7.625%, 12/1/17, Ser.
Aaa               1,375(D)   D....................     1,547,329
                           7.50%, 12/1/19, Ser.
Aaa               4,650(D)   K....................     5,282,260
                           Pennsylvania St. Univ.,
                             Gen. Oblig.,
A1                3,000    5.55%, 8/15/07.........     2,937,570
NR                1,000(D) 6.75%, 7/1/09..........     1,096,310
                           Philadelphia Arpt.
                             Rev.,
Baa               2,000    9.00%, 6/15/15.........     2,142,720
                           Philadelphia Gas Wks.
                             Rev.,
                           7.20%, 6/15/98, Ser.
Baa1                500      13...................       534,990
                           7.30%, 6/15/99, Ser.
Baa1                625      13...................       673,350
                           7.70%, 6/15/11, Ser.
Baa1                215      13...................       249,363
                           6.375%, 7/1/14, Ser.
Baa1              1,000      14...................       997,100
                           7.70%, 6/15/21, Ser.
Aaa               3,430(D)   13...................     3,982,539
                           6.375%, 7/1/26, Ser.
Baa1              2,900      14...................     2,824,571
                           Philadelphia Hosps. &
                             Higher Ed. Fac. Auth.
                             Rev.,
                           Childrens' Hosp. Proj.,
                           5.00%, 2/15/21, Ser.
Aa                2,000      A....................     1,656,080
                           Grad. Hlth. Systems,
A-*               1,000    7.00%, 8/15/12.........     1,033,220
                           7.00%, 8/15/17, Ser.
A-*               1,000      A....................     1,032,480
                           Childrens' Seashore
                             House,
                           6.25%, 7/1/18, Ser.
Baa1              1,000      A....................       913,520
Baa1              2,750    7.25%, 7/1/18..........     2,811,600
</TABLE>
 
                                      -7-     See Notes to Financial Statements.

<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                      
PENNSYLVANIA SERIES                                            
<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                  Value            
(Unaudited)     (000)          Description(a)         (Note 1)       
<C>           <C>          <S>                      <C>
                           Philadelphia Ind. Dev.
                             Auth. Rev.,
                           Inst. For Cancer
                             Research,
                           7.25%, 7/1/10, Ser.
AA-*           $  5,770      B....................  $  6,204,539
                           Nat'l. Brd. Of Med.
                             Examiners Proj.,
A+*               5,000    6.75%, 5/1/12..........     5,399,800
                           Philadelphia Mun. Auth.
                             Rev.,
                           5.625%, 11/15/14,
Aaa               2,000      F.G.I.C..............     1,866,140
                           5.625%, 11/15/18,
Aaa               2,000      F.G.I.C..............     1,835,540
                           Philadelphia Pkg. Auth.
                             Rev.,
                           Arpt. Pkg.,
                           7.375%, 9/1/18,
Aaa               2,200      A.M.B.A.C............     2,411,662
                           Philadelphia
                             Pennsylvania
                             Sch. Dist. Ser. A
Aaa               1,710    5.85%, 7/1/09..........     1,716,566
                           Philadelphia Redev.
                             Auth. Rev.,
                           Home Impvt. Loan,
                           7.375%, 6/1/03, Ser.
A                   390      A....................       408,685
                           7.40%, 6/1/08, Ser.
A                   385      A....................       393,224
                           Philadelphia Wtr. &
                             Swr. Rev.,
                           Zero Coupon, 10/1/02,
Aaa               7,900      Ser. 15, M.B.I.A.....     5,167,706
                           6.875%, 10/1/06, Ser.
Aaa                 700      15, M.B.I.A..........       749,532
                           5.25%, 6/15/23,
Aaa               4,375      M.B.I.A..............     3,757,337
                           Pittsburgh Stadium Auth. Rev.,
                           7.50%, 10/15/01,
Aaa                 500      F.G.I.C..............       539,945
                           Pittsburgh Urban Redev.
                             Auth.,
                             Mtge. Rev.,
                           8.30%, 4/1/17, Ser.
A1                  795      B....................       859,252
                           Pottstown Boro. Swr. Auth. Rev.,
                           Zero Coupon, 11/1/03,
Aaa               1,200      F.G.I.C..............       734,976
                           Puerto Rico Comnwlth.,
                           Zero Coupon, 7/1/08,
Aaa               3,340      M.B.I.A..............     3,339,833
                           Pub. Impvt. Ref.,
                           5.40%, 7/1/07,
Aaa               2,500      M.B.I.A..............     2,488,325
Aaa                 720    7.00%, 7/1/10..........       807,833
                           Puerto Rico Comnwlth.,
                             Gen. Oblig.,
                           7.00%, 7/1/10,
Aaa               3,030      A.M.B.A.C............     3,399,630
                           Puerto Rico Comnwlth.,
                             Gen. Oblig.,
                           8.393%, 7/1/20, Ser. A,
Aaa            $  4,250(D)(D)   F.S.A................ $  3,984,375
                           Puerto Rico Elec. Pwr.
                             Auth. Pwr. Rev.
                           7.00%, 7/1/06, Ser.
Baa1              1,800      S....................     2,014,038
                           Puerto Rico Hsg. Fin. Auth. Rev.,
Baa                 750    5.125%, 12/1/05........       703,215
                           Multifamily Mtge.,
AA*                 835    7.50%, 4/1/22..........       869,110
                           Sngl. Fam.,
Baa               1,000    5.25%, 12/1/06.........       934,660
                           Puerto Rico Hwy. &
                             Trans. Auth. Rev.,
                           6.625%, 7/1/18, Ser.
AAA*              1,540(D)   T....................     1,622,664
                           Puerto Rico Pub.
                             Impvt.,
Aaa               5,250(D)@ 7.70%, 7/1/20..........    6,072,465
Baa1              1,100(D) 6.80%, 7/1/21..........     1,232,055
                           Sayre Hlth. Care Facs. Auth. Rev.,
                           Cap. Asset Fin. Prog.,
                           7.70%, 12/1/13,
Aaa                 500      A.M.B.A.C............       563,215
                           7.625%, 12/1/15, Ser.
                             H-2,
Aaa               1,000      A.M.B.A.C............     1,142,420
                           Scranton Pkg. Auth.
                             Rev.,
A+*               1,600    8.125%, 9/15/14........     1,774,592
                           Scranton-Lackawanna
                             Hlth. & Welfare Auth.
                             Rev.,
                           Univ. Of Scranton
                             Proj.,
                           7.50%, 6/15/06, Ser.
A-*               1,000(D)   C....................     1,139,230
A-*               2,250    6.50%, 3/1/15..........     2,239,875
                           Shaler Twnshp., Gen
                             Oblig.,
                           5.00%, 8/15/17, Ser. B,
Aaa               1,000      F.G.I.C..............       844,360
                           So. Fork Mun. Auth.
                             Hosp. Rev.,
                           Lee Hosp. Proj.,
                           5.50%, 7/1/23, Ser.
A-*               2,500      A....................     2,152,825
                           Swarthmore Boro. Gen.
                             Auth. Rev., Pa.
                             Coll.,
A-*                 600(D) 7.25%, 9/15/10.........       673,392
                           Venango Cnty. Gen.
                             Oblig.,
                           5.25%, 7/15/18, Ser.
Aaa               2,265      B....................     1,993,449
</TABLE>
 
                                      -8-     See Notes to Financial Statements.

<PAGE>
PRUDENTIAL MUNICIPAL SERIES FUND                      
PENNSYLVANIA SERIES                                            
<TABLE>
<CAPTION>
  Moody's     Principal                                                
   Rating      Amount                                  Value            
(Unaudited)     (000)          Description(a)         (Note 1)       
<C>           <C>          <S>                      <C>
                           Virgin Islands Pub. Fin. Auth. Rev.,
                             Hwy. Trans. Gas Tax,
BBB*           $  1,000    7.70%, 10/1/04.........  $  1,092,870
                           Ref. Matching Loan
                             Notes,
                           7.25%, 10/1/18, Ser.
NR                1,950      A....................     2,011,659
                           Virgin Islands Terr.,
                             Hugo Ins. Claims Fund
                             Proj.,
NR                1,105    7.75%, 10/1/06.........     1,208,240
                           Virgin Islands Wtr. &
                             Pwr. Auth.,
                             Elec. Sys. Rev.,
                           8.50%, 1/1/10, Ser.
NR                1,400      A....................     1,537,984
                           Washington Cnty. Auth.
                             Lease Rev.,
                             Mun. Fac., Shadyside
                             Hosp.,
                           7.45%, 12/15/18,
                             Ser. C-1D,
Aaa               2,900(D)   A.M.B.A.C............     3,319,949
                           Washington Cnty. Hosp. Auth. Rev.,
                             Monongahela Valley Hosp.,
A                 2,750    6.75%, 12/1/08.........     2,846,250
                           Washington Cnty. Ind.
                             Dev. Auth. Rev.,
                             Presbyterian Med.
                             Ctr.,
                           6.70%, 1/15/12,
AAA*              1,000      F.H.A................     1,021,600
                           York Cnty. Solid Waste
                             &
                             Refuse Auth. Ind.
                             Dev. Rev.,
                             Res. Rec. Proj.,
                           8.20%, 12/1/14, Ser.
AA-*              1,000      C....................     1,084,810
                                                    ------------
                           Total long-term
                             investments
                             (cost
                             $248,637,780)........   260,480,906
                                                    ------------
                           SHORT-TERM INVESTMENTS--2.4%
                           Allegheny Cnty. Hosp.
                             Dev.
                             Auth. Rev.,
                           3.20%, 9/1/94, Ser. A,
VMIG1               300      F.R.W.D..............       300,000
                           3.20%, 9/1/94, Ser. B,
VMIG1             2,100      F.R.W.D..............     2,100,000
                           Emmaus Pennsylvania
                             Gen.
                             Auth. Rev.
                             Local Gov't. Sub.
                             B-7,
A-1*           $  1,000    3.15%, 9/7/94..........  $  1,000,000
                           Puerto Rico Comnwlth.,
                           Gov't. Dev. Bank.,
                           2.90%, 9/7/94, Ser. 85,
VMIG1               600      F.R.W.D.,............       600,000
                           Schuylkill Cnty. Ind.
                             Dev. Auth., F.R.D.D.,
                           3.30%, 9/1/94, Ser.
P1                2,300      85...................     2,300,000
                                                    ------------
                           Total short-term
                             investments
                             (cost $6,300,000)....     6,300,000
                                                    ------------
                           Total Investments--99.4%
                           (cost $254,937,780;
                             Note 4)..............   266,780,906
                           Other assets in excess
                             of
                             liabilities--0.6%....     1,693,253
                                                    ------------
                           Net Assets--100%.......  $268,474,159
                                                    ------------
                                                    ------------
</TABLE>
 
- ---------------
(a) The following abbreviations are used in portfolio descriptions:
   A.M.B.A.C.--American Municipal Bond Assurance Corporation.
    B.I.G.--Bond Investors Guaranty Insurance Company.
    C.G.I.C.--Capital Guaranty Insurance Company.
    F.G.I.C.--Financial Guaranty Insurance Company.
    F.H.A.--Federal Housing Administration.
    F.R.D.D.--Floating Rate (Daily) Demand Note#.
    F.R.W.D.--Floating Rate (Weekly) Demand Note#.
    F.S.A.--Financial Security Assurance.
    G.N.M.A.--Government National Mortgage Association.
    M.B.I.A.--Municipal Bond Insurance Association.
   # For purposes of amortized cost valuation, the
     maturity date of these securities are considered
     to be the later of the next date on which the
     security can be redeemed at par, or the next date
     on which the rate of interest is adjusted.
   * Standard & Poor's rating.
 (D) Prerefunded issues are secured by escrowed cash
     and/or direct U.S. guaranteed obligations.
(D)(D) Inverse floating rate bond. The coupon is
     inversely indexed to a floating interest rate. The
     rate shown is the rate at the period end.
   @ Pledged as initial margin on financial futures
     contracts.
NR--Not Rated by Moody's or Standard & Poor's.

The Fund's current Statement of Additional Information contains a 
description of Moody's and Standard & Poor's ratings.
                                      -9-     See Notes to Financial Statements.

<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 PENNSYLVANIA SERIES
 Statement of Assets and Liabilities
<TABLE>
<CAPTION>
Assets                                                                                      August 31, 1994
                                                                                            ---------------
<S>                                                                                         <C>
Investments, at value (cost $254,937,780)................................................    $ 266,780,906
Cash.....................................................................................          127,413
Interest receivable......................................................................        4,180,051
Receivable for investments sold..........................................................        1,279,398
Receivable for Series shares sold........................................................          290,082
Deferred expenses and other assets.......................................................           29,658
                                                                                            ---------------
    Total assets.........................................................................      272,687,508
                                                                                            ---------------
Liabilities
Payable for investments purchased........................................................        3,394,576
Payable for Series shares reacquired.....................................................          342,915
Dividends payable........................................................................          224,250
Management fee payable...................................................................          114,034
Distribution fee payable.................................................................          110,445
Due to broker - variation margin.........................................................           26,119
Deferred Trustees' fees..................................................................            1,010
                                                                                            ---------------
    Total liabilities....................................................................        4,213,349
                                                                                            ---------------
Net Assets...............................................................................    $ 268,474,159
                                                                                            ---------------
                                                                                            ---------------
Net assets were comprised of:
  Shares of beneficial interest, at par..................................................    $     257,606
  Paid-in capital in excess of par.......................................................      257,812,482
                                                                                            ---------------
                                                                                               258,070,088
  Accumulated net realized loss on investments...........................................       (1,299,743)
  Net unrealized appreciation on investments.............................................       11,703,814
                                                                                            ---------------
  Net assets, August 31, 1994............................................................    $ 268,474,159
                                                                                            ---------------
                                                                                            ---------------
Class A:
  Net asset value and redemption price per share
    ($10,651,317 / 1,021,931 shares of beneficial interest issued and outstanding).......           $10.42
  Maximum sales charge (3% of offering price)............................................              .32
                                                                                            ---------------
  Maximum offering price to public.......................................................           $10.74
                                                                                            ---------------
                                                                                            ---------------
Class B:
  Net asset value, offering price and redemption price per share
    ($257,732,481 / 24,730,032 shares of beneficial interest issued and outstanding).....           $10.42
                                                                                            ---------------
                                                                                            ---------------
Class C:
  Net asset value, offering price and redemption price per share
    ($90,361 / 8,669 shares of beneficial interest issued and outstanding)...............           $10.42
                                                                                            ---------------
                                                                                            ---------------
</TABLE>
 
See Notes to Financial Statements.
                                      -10-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 PENNSYLVANIA SERIES
 Statement of Operations
<TABLE>
<CAPTION>
                                         Year Ended
                                         August 31,
Net Investment Income                       1994
                                        ------------
<S>                                     <C>
Income
  Interest............................  $ 17,360,812
                                        ------------
Expenses
  Management fee......................     1,384,548
  Distribution fee--Class A...........        10,315
  Distribution fee--Class B...........     1,332,972
  Transfer agent's fees and
  expenses............................       187,000
  Custodian's fees and expenses.......       118,000
  Reports to shareholders.............        56,000
  Registration fees...................        36,000
  Legal fees..........................        15,000
  Audit fee...........................        10,500
  Trustee's fees......................         3,375
  Miscellaneous.......................        13,788
                                        ------------
Total expenses........................     3,167,498
                                        ------------
Net investment income.................    14,193,314
                                        ------------
Realized and Unrealized Gain (Loss) on
Investments
Net realized gain (loss) on:
  Investment transactions.............       282,442
  Financial futures transactions......      (290,241)
                                        ------------
                                              (7,799)
                                        ------------
Net change in unrealized appreciation/depreciation
  on:
  Investments.........................   (17,643,912)
  Financial futures contracts.........      (139,312)
                                        ------------
                                         (17,783,224)
                                        ------------
Net loss on investments...............   (17,791,023)
                                        ------------
Net Decrease in Net Assets Resulting
from Operations.......................  $ (3,597,709)
                                        ------------
                                        ------------
</TABLE>
 
 PRUDENTIAL MUNICIPAL SERIES FUND
 PENNSYLVANIA SERIES
 Statement of Changes in Net Assets
<TABLE>
<CAPTION>
                               Year Ended August 31,
Increase (Decrease)         ---------------------------
in Net Assets                   1994           1993
                            ------------   ------------
<S>                         <C>            <C>
Operations
  Net investment income...  $ 14,193,314   $ 12,582,197
  Net realized gain (loss)
    on
    investment
    transactions..........        (7,799)     2,222,982
  Net change in unrealized
 appreciation/depreciation
    of investments........   (17,783,224)    13,704,514
                            ------------   ------------
  Net increase (decrease)
    in net
    assets resulting from
    operations............    (3,597,709)    28,509,693
                            ------------   ------------
Dividends and
  distributions (Note 1):
  Dividends to
    shareholders from
    net investment income
    Class A...............      (569,122)      (417,688)
    Class B...............   (13,624,192)   (12,164,509)
                            ------------   ------------
                             (14,193,314)   (12,582,197)
                            ------------   ------------
  Distributions to
    shareholders from net
    realized gain on
    investment
    transactions
    Class A...............       (97,328)       (23,310)
    Class B...............    (2,598,620)      (813,755)
                            ------------   ------------
                              (2,695,948)      (837,065)
                            ------------   ------------
Series share transactions
  (Note 5)
  Net proceeds from shares
    sold..................    46,954,314     65,604,598
  Net asset value of
    shares
    issued in reinvestment
    of dividends and
    distributions.........     9,903,212      7,674,719
  Cost of shares
  reacquired..............   (40,990,785)   (27,211,612)
                            ------------   ------------
  Net increase in net
    assets
    from Series share
    transactions..........    15,866,741     46,067,705
                            ------------   ------------
Total increase
  (decrease)..............    (4,620,230)    61,158,136
Net Assets
Beginning of year.........   273,094,389    211,936,253
                            ------------   ------------
End of year...............  $268,474,159   $273,094,389
                            ------------   ------------
                            ------------   ------------
</TABLE>
 
See Notes to Financial Statements.        See Notes to Financial Statements.
                                      -11-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 PENNSYLVANIA SERIES
 Notes to Financial Statements
   Prudential Municipal Series Fund (the ``Fund'') is registered under the
Investment Company Act of 1940 as an open-end investment company. The Fund was
organized as a Massachusetts business trust on May 18, 1984 and consists of
seventeen series. The monies of each series are invested in separate,
independently managed portfolios. The Pennsylvania Series (the ``Series'')
commenced investment operations in April, 1987. The Series is diversified and
seeks to achieve it's investment objective of obtaining the maximum amount of
income exempt from federal and applicable state income taxes with the minimum of
risk by investing in ``investment grade'' tax-exempt securities whose ratings
are within the four highest ratings categories by a nationally recognized
statistical rating organization or, if not rated, are of comparable quality. The
ability of the issuers of the securities held by the Series to meet their
obligations may be affected by economic developments in a specific state,
industry or region.
                              
Note 1. Accounting            The following is a summary
Policies                      of significant accounting poli-
                              cies followed by the Fund, and the Series, in the
preparation of its financial statements.
Securities Valuations: The Series values municipal securities (including
commitments to purchase such securities on a ``when-issued'' basis) on the basis
of prices provided by a pricing service which uses information with respect to
transactions in bonds, quotations from bond dealers, market transactions in
comparable securities and various relationships between securities in
determining values. If market quotations are not readily available from such
pricing service, a security is valued at its fair value as determined under
procedures established by the Trustees.
   Short-term securities which mature in more than 60 days are valued at current
market quotations. Short-term securities which mature in 60 days or less are
valued at amortized cost.
   All securities are valued as of 4:15 P.M., New York time.
Securities Transactions and Investment Income: Securities transactions are
recorded on the trade date. Realized gains and losses on sales of securities are
calculated on the identified cost basis. Interest income is recorded on the
accrual basis. The Series amortizes premiums and original issue discount paid on
purchases of portfolio securities as adjustments to interest income.
   Net investment income (other than distribution fees) and unrealized and
realized gains or losses are allocated daily to each class of shares based upon
the relative proportion of net assets of each class at the beginning of the day.
Financial Futures Contracts: A financial futures contract is an agreement to
purchase (long) or sell (short) an agreed amount of debt securities at a set
price for delivery on a future date. Upon entering into a financial futures
contract, the Series is required to pledge to the broker an amount of cash
and/or other assets equal to a certain percentage of the contract amount. This
amount is known as the ``initial margin''. Subsequent payments, known as
``variation margin'', are made or received by the Series each day, depending on
the daily fluctuations in the value of the underlying security. Such variation
margin is recorded for financial statement purposes on a daily basis as
unrealized gain or loss. The Series invests in financial futures contracts
solely for the purpose of hedging its existing portfolio securities or
securities the Series intends to purchase against fluctuations in value caused
by changes in prevailing market conditions. Should market conditions move
unexpectedly, the Series may not achieve the anticipated benefits of the
financial futures contracts and may realize a loss. The use of futures
transactions involves the risk of imperfect correlation in movements in the
price of futures contracts, interest rates and the underlying hedged assets.
Federal Income Taxes: For federal income tax purposes, each series in the Fund
is treated as a separate taxpaying entity. It is the intent of the Series to
continue to meet the requirements of the Internal Revenue Code applicable to
regulated investment companies and to distribute all of its net income to
shareholders. For this reason and because substantially all of the Series' gross
income consists of tax-exempt interest, no federal income tax provision is
required.
Dividends and Distributions: The Series declares daily dividends from net
investment income. Payment of dividends are made monthly. Distributions of net
capital gains, if any, are made annually. Income distributions and capital gain
distributions are determined in accordance with income tax regulations which may
differ from generally accepted accounting principles.
                              
Note 2. Agreements            The Fund has a management
                              agreement with Prudential
                                      -12-
 <PAGE>
<PAGE>
Mutual Fund Management, Inc. (``PMF''). Pursuant to this agreement, PMF has
responsibility for all investment advisory services and supervises the
subadviser's performance of such services. PMF has entered into a subadvisory
agreement with The Prudential Investment Corporation (``PIC''); PIC furnishes
investment advisory services in connection with the management of the Fund. PMF
pays for the cost of the subadviser's services, the compensation of officers of
the Fund, occupancy and certain clerical and bookkeeping costs of the Fund. The
Fund bears all other costs and expenses.
   The management fee paid PMF is computed daily and payable monthly, at an
annual rate of .50 of 1% of the average daily net assets of the Series.
   The Fund has distribution agreements with Prudential Mutual Fund
Distributors, Inc. (``PMFD''), which acts as the distributor of the Class A
shares of the Fund, and with Prudential Securities Incorporated (``PSI''), which
acts as distributor of the Class B and Class C shares of the Fund (collectively
the ``Distributors''). The Fund compensates the Distributors for distributing
and servicing the Fund's Class A, Class B and Class C shares, pursuant to plans
of distribution, (the ``Class A, B and C Plans'') regardless of expenses
actually incurred by them. The distribution fees are accrued daily and payable
monthly.
   On July 19, 1994, shareholders of the Fund approved amendments to the Class A
and Class B distribution plans under which the distribution plans became
compensation plans, effective August 1, 1994. Prior thereto, the distribution
plans were reimbursement plans, under which PMFD and PSI were reimbursed for
expenses actually incurred by them up to the amount permitted under the Class A
and Class B Plans, respectively. The Fund is not obligated to pay any prior or
future excess distribution costs (costs incurred by the Distributors in excess
of distribution fees paid by the Fund or contingent deferred sales charges
received by the Distributors). The rate of the distribution fees charged to
Class A and Class B shares of the Fund did not change under the amended plans of
distribution. The Fund began offering Class C shares on August 1, 1994.
   Pursuant to the Class A, B and C Plans, the Fund compensates the Distributors
for distribution-related activities at an annual rate of up to .30 of 1%, .50 of
1% and 1%, of the average daily net assets of the Class A, B and C shares,
respectively. Such expenses under the Plans were .10 of 1%, .50 of 1% and .75 of
1% of the average daily net assets of the Class A, B and C shares, respectively,
for the fiscal year ended August 31, 1994.
   PMFD has advised the Series that it has received approximately $126,400 in
front-end sales charges resulting from sales of Class A shares during the fiscal
year ended August 31, 1994. From these fees, PMFD paid such sales charges to PSI
and Pruco Securities Corporation, affiliated broker-dealers, which in turn paid
commissions to salespersons and incurred other distribution costs.
   PSI has advised the Series that for the fiscal year ended August 31, 1994, it
received approximately $365,000 in contingent deferred sales charges imposed
upon certain redemptions by Class B shareholders.
   PMFD is a wholly-owned subsidiary of PMF; PSI, PMF and PIC are indirect,
wholly-owned subsidiaries of The Prudential Insurance Company of America.
                              
Note 3. Other                 Prudential Mutual Fund Ser-
Transactions                  vices, Inc. (``PMFS''), a 
with Affiliates               wholly-owned subsidiary of 
                              PMF, serves as the Fund's transfer agent. During
the year ended August 31, 1994, the Series incurred fees of approximately
$131,000 for the services of PMFS. As of August 31, 1994, approximately $11,000
of such fees were due to PMFS. Transfer agent fees and expenses in the Statement
of Operations includes certain out-of-pocket expenses paid to non-affiliates.
                              
Note 4. Portfolio             Purchases and sales of port-
Securities                    folio securities of the Series, 
                              excluding short-term investments, for the year
ended August 31, 1994 were $73,332,703 and $59,206,623, respectively.
   The cost basis of investments for federal income tax purposes was
$254,970,360 and, accordingly, as of August 31, 1994 net unrealized appreciation
of investments, including short-term investments, for federal income tax
purposes is $11,810,546 (gross unrealized appreciation--$15,211,468; gross
unrealized depreciation--$3,400,922).
   At August 31, 1994 the Series sold 95 financial futures contracts on the
Municipal Bond Index expiring September 1994. The value at disposition of such
contracts on August 31, 1994 was $8,553,188. The value of such contracts on
August 31, 1994 was $8,692,500 thereby resulting in an unrealized loss of
$139,312.
   The Fund will elect to treat net capital losses of approximately $1,202,900
incurred in the ten month period ended August 31, 1994 as having been incurred
in the following fiscal year.
                              
Note 5. Capital               The Series offers both Class
                              A, Class B and Class C shares. Class A shares are
sold with a front-end sales charge of up to 3%. Class B shares are sold with a
contingent deferred sales charge which declines from 5% to zero
                                      -13-
 <PAGE>
<PAGE>
depending on the period of time the shares are held. Class C shares are sold
with a contingent deferred sales charge of 1% during the first year. Class B
shares will automatically convert to Class A shares on a quarterly basis
approximately seven years after purchase commencing in or about February 1995.
   The Fund has authorized an unlimited number of shares of beneficial interest
of each class at $.01 par value per share. Transactions in shares of beneficial
interest for the fiscal years ended August 31, 1994 and August 31, 1993 were as
follows:
<TABLE>
<CAPTION>
Class A                            Shares         Amount
- ------------------------------   ----------    ------------
<S>                              <C>           <C>
Year ended August 31, 1994:
Shares sold...................      319,034    $  3,481,332
Shares issued in reinvestment
  of
  dividends and
  distributions...............       36,716         396,391
Shares reacquired.............     (167,304)     (1,791,755)
                                 ----------    ------------
Net increase in shares
  outstanding.................      188,446    $  2,085,968
                                 ----------    ------------
                                 ----------    ------------
Year ended August 31, 1993:
Shares sold...................      398,287    $  4,306,639
Shares issued in reinvestment
  of
  dividends and
  distributions...............       22,903         247,493
Shares reacquired.............     (147,976)     (1,607,135)
                                 ----------    ------------
Net increase in shares
  outstanding.................      273,214    $  2,946,997
                                 ----------    ------------
                                 ----------    ------------
<CAPTION>
Class B                            Shares         Amount
- ------------------------------   ----------    ------------
<S>                              <C>           <C>
Year ended August 31, 1994:
Shares sold...................    3,979,725    $ 43,382,782
Shares issued in reinvestment
  of
  dividends and
  distributions...............      879,774       9,506,821
Shares reacquired.............   (3,665,816)    (39,199,030)
                                 ----------    ------------
Net increase in shares
  outstanding.................    1,193,683    $ 13,690,573
                                 ----------    ------------
                                 ----------    ------------
Year ended August 31, 1993:
Shares sold...................    5,687,242    $ 61,297,959
Shares issued in reinvestment
  of
  dividends and
  distributions...............      689,051       7,427,226
Shares reacquired.............   (2,382,063)    (25,604,477)
                                 ----------    ------------
Net increase in shares
  outstanding.................    3,994,230    $ 43,120,708
                                 ----------    ------------
                                 ----------    ------------
<CAPTION>
Class C
- ------------------------------
<S>                              <C>           <C>
August 1, 1994* through
  August 31, 1994:
Shares sold...................        8,669    $     90,200
                                 ----------    ------------
                                 ----------    ------------
</TABLE>
 
- ---------------
* Commencement of offering of Class C shares.
                                      -14-
 <PAGE>
<PAGE>
 PRUDENTIAL MUNICIPAL SERIES FUND
 PENNSYLVANIA SERIES
 Financial Highlights
<TABLE>
<CAPTION>
                              Class A                                                                                   Class C
         -------------------------------------------------                          Class B                            ----------
                                              January 22,    ------------------------------------------------------    August 1,
                                               1990(D)(D)                                                              1994(D)(D)(D)
               Year Ended August 31,            Through                      Year Ended August 31,                      Through
         ----------------------------------    August 31,    ------------------------------------------------------    August 31,
          1994      1993     1992     1991        1990         1994       1993       1992        1991        1990         1994
<S>      <C>       <C>      <C>      <C>      <C>            <C>        <C>        <C>         <C>         <C>         <C>
         -------   ------   ------   ------   ------------   --------   --------   --------    --------    --------    ----------
PER SHARE
  OPERATING
  PERFORMANCE:
Net
  asset
 value,
 beginning
  of
  period... $ 11.21 $10.55  $ 9.96   $ 9.60      $ 9.83      $  11.21   $  10.54   $   9.96    $   9.60    $   9.81      $10.44
            ------- ------  ------   ------   ------------   --------   --------   --------    --------    --------    ----------
Income
  from
  investment
  operations:
Net
investment
 income...     .59    .62      .62      .62(D)      .38(D)        .55        .57        .58         .58(D)      .61(D)        .04
Net
realized
  and
  unrealized
  gain
 (loss)
  on
  investment
  trans-
  actions..   (.68)    .70     .59      .39        (.23)        (.68)       .71        .58         .39        (.21)       (.02)
            ------- ------  ------   ------   ------------   --------   --------   --------    --------    --------    ----------
  Total
   from
   investment
    opera-
    tions..   (.09)   1.32    1.21     1.01         .15         (.13)      1.28       1.16         .97         .40         .02
            ------- ------  ------   ------   ------------   --------   --------   --------    --------    --------    ----------
Less
distributions:
Dividends
  from
  net
  investment
  income...   (.59)   (.62)   (.62)    (.62)       (.38)        (.55)      (.57)      (.58)       (.58)       (.61)       (.04)
Distributions
  from net
  realized
  gains...    (.11)   (.04)     --     (.03)         --         (.11)      (.04)        --        (.03)         --          --
            ------- ------  ------   ------   ------------   --------   --------   --------    --------    --------    ----------
  Total
  distri-
  butions.    (.70)   (.66)   (.62)    (.65)       (.38)        (.66)      (.61)      (.58)       (.61)       (.61)       (.04)
            ------- ------  ------   ------   ------------   --------   --------   --------    --------    --------    ----------
Net
  asset
 value,
  end
  of
  period.. $ 10.42  $11.21  $10.55   $ 9.96      $ 9.60      $ 10.42   $  11.21   $  10.54    $   9.96    $   9.60      $10.42
            ------- ------  ------   ------   ------------   --------   --------   --------    --------    --------    ----------
            ------- ------  ------   ------   ------------   --------   --------   --------    --------    --------    ----------
TOTAL
RETURN#:...   (.82)% 12.86%  12.44%   10.82%       1.43%       (1.22)%    12.54%     11.92%      10.39%       4.08%        .14%
RATIOS/SUPPLEMENTAL
  DATA:
Net
assets,
  end
  of
 period
 (000)... $10,651  $9,342   $5,908   $3,521      $1,823      $257,732   $263,752   $206,028    $170,162    $150,824      $   90
Average
  net
 assets
 (000)... $10,315  $7,354   $4,439   $2,366      $  977      $266,594   $229,955   $186,113    $146,591    $141,183      $    1
Ratios
  to
average
  net
  assets:##
  Expenses,
  including
  distribution
  fees...      .75%    .78%    .81%     .83%(D)     .78%*(D)    1.15%      1.18%      1.21%       1.23%(D)    1.02%(D)    2.00%*
  Expenses,
  excluding
  distribution
fees...        .65%    .68%    .71%     .74%(D)     .68%*(D)     .65%       .68%       .71%        .74%(D)        .53%(D) 1.25%*
  Net
  investment
  income...   5.52%   5.69%   5.99%    6.32%(D)    6.51%*(D)    5.11%      5.29%      5.59%       5.94%(D)       6.05%(D) 8.51%*
Portfolio
turnover...     22%     13%     25%      62%         37%          22%        13%        25%         62%            37%      22%

 
- ---------------
   * Annualized.
 (D) Net of expense subsidy/management fee waiver.
(D)(D) Commencement of offering of Class A shares.
(D)(D)(D) Commencement of offering of Class C shares.
   # Total return does not consider the effects of sales loads. Total return is calculated assuming a purchase of
     shares on the first day and a sale on the last day of each period reported and includes reinvestment dividends
     and distributions. Total returns for periods of less than a full year are not annualized.
  ## Because of the events referred to in (D)(D)(D) and the timing of such, the ratios for the Class C shares are
     not necessarily comparable to that of Class A or B shares and are not necessarily indicative of future ratios.

</TABLE> 
See Notes to Financial Statements.
                                      -15-
 <PAGE>
<PAGE>
                          INDEPENDENT AUDITORS' REPORT
The Shareholders and Board of Trustees
Prudential Municipal Series Fund, Pennsylvania Series
   We have audited the accompanying statement of assets and liabilities of
Prudential Municipal Series Fund, Pennsylvania Series, including the portfolio
of investments, as of August 31, 1994, the related statements of operations for
the year then ended and of changes in net assets for each of the two years in
the period then ended, and the financial highlights for each of the five years
in the period then ended. These financial statements and financial highlights
are the responsibility of the Fund's management. Our responsibility is to
express an opinion on these financial statements and financial highlights based
on our audits.
   We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements and financial
highlights are free of material misstatement. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements. Our procedures included confirmation of the securities owned as of
August 31, 1994 by correspondence with the custodian and brokers; where replies
were not received from brokers, we performed other auditing procedures. An audit
also includes assessing the accounting principles used and significant estimates
made by management, as well as evaluating the overall financial statement
presentation. We believe that our audits provide a reasonable basis for our
opinion.
   In our opinion, such financial statements and financial highlights present
fairly, in all material respects, the financial position of Prudential Municipal
Series Fund, Pennsylvania Series, as of August 31, 1994, the results of its
operations, the changes in its net assets, and its financial highlights for the
respective stated periods in conformity with generally accepted accounting
principles.
Deloitte & Touche LLP
New York, New York
October 17, 1994
                         FEDERAL INCOME TAX INFORMATION
   We are required by the Internal Revenue Code to advise you within 60 days of
the Series' fiscal year end (August 31, 1994) as to the federal tax status of
dividends and distributions paid by the Series during such fiscal year.
Accordingly, we are advising you that in the fiscal year ended August 31, 1994,
dividends paid from net investment income of $.59 per share for Class A shares,
$.55 per share for Class B shares and $.04 per share for Class C shares were all
federally tax-exempt interest dividends. In addition, the Series paid to both
Class A and B shares a long-term capital gain distribution of $.076 per share
which is taxable as such and a short-term capital gain distribution of $.031 per
share, which is taxable as ordinary income.
   In January 1995, you will be advised on IRS Form 1099 DIV or substitute 1099
DIV as to the federal tax status of the dividends and distributions received by
you in calendar year 1994.
                                      -16-
 <PAGE>
<PAGE>

   These graphs are furnished to you in accordance with SEC regulations. They
compare a $10,000 investment in Prudential Municipal Series Fund: Pennsylvania
Series (Class A, Class B, and Class C) with a similar investment in the Lehman
Brothers Municipal Bond Index (the Index) by portraying the initial account
values at the commencement of operations of each class and subsequent account
values at the end of each fiscal year (August 31) beginning in 1990 for Class A,
in 1987 for Class B shares and 1994 for Class C shares. For purposes of the
graphs and, unless otherwise indicated, the accompanying tables, it has been
assumed that
(a) the maximum sales charge was deducted from the initial $10,000 investment in
Class A shares; (b) the maximum applicable contingent deferred sales charge was
deducted from the value of the investment in Class B shares and Class C shares,
assuming full redemption on August 31, 1994; (c) all recurring fees (including
management fees) were deducted; and (d) all dividends and distributions were
reinvested. Class B shares will automatically convert to Class A shares on a
quarterly basis approximately seven years after purchase. This conversion
feature is expected to be implemented on or about February 1995 and is not
reflected in the graph. The graph and accompanying tables reflect the past
subsidy and/or waiver of expenses and/or management fees. Without fee waivers
and expense subsidies, the value of a $10,000 investment in the Series and the
Series' average annual total return, as shown above, would have been lower.
   The Index is a weighted index comprised of 21,000 municipal bonds (general
obligation bonds, revenue bonds, insured bonds and prerefunded bonds) selected
by Lehman Brothers as representative of the long-term investment grade municipal
bond market. The Index is an unmanaged index and includes the reinvestment of
all income, but does not reflect the payment of transaction costs and advisory
fees associated with an investment in the Series. The securities which comprise
the Index may differ substantially from the securities in the Series' portfolio
because the Index, among other things, is not state specific. The Lehman
Brothers Municipal Bond Index is not the only index which may be used to
characterize performance of long-term, investment-grade tax-exempt bond funds
and other indexes may portray different comparative performance.
                                      -17-
 <PAGE>
<PAGE>
Trustees
Edward D. Beach
Eugene C. Dorsey
Delayne Dedrick Gold
Harry A. Jacobs, Jr.
Lawrence C. McQuade
Thomas T. Mooney
Thomas H. O'Brien
Richard A. Redeker
Nancy Hays Teeters

Officers
Lawrence C. McQuade, President
Robert F. Gunia, Vice President
Susan C. Cote, Treasurer
S. Jane Rose, Secretary
Ronald Amblard, Assistant Secretary
Deborah A. Docs, Assistant Secretary

Manager
Prudential Mutual Fund Management, Inc.
One Seaport Plaza
New York, NY 10292

Investment Adviser
The Prudential Investment Corporation
Prudential Plaza
Newark, NJ 07101

Distributors
Prudential Mutual Fund Distributors, Inc.
Prudential Securities Incorporated
One Seaport Plaza
New York, NY 10292

Custodian
State Street Bank and Trust Company
One Heritage Drive
North Quincy, MA 02171

Transfer Agent
Prudential Mutual Fund Services, Inc.
P.O. Box 15005
New Brunswick, NJ 08906

Independent Accountants
Deloitte & Touche LLP
1633 Broadway
New York, NY 10019

Legal Counsel
Gardner, Carton & Douglas
Quaker Tower
321 North Clark Street
Chicago, IL 60610-4795

Prudential Mutual Funds
One Seaport Plaza
New York, NY 10292
Toll free (800) 225-1852, Collect (908) 417-7555

This report is not authorized for distribution to prospective 
investors unless preceded or accompanied by a current prospectus.

74435M879
74435M887                       MF 132E
74435M481      (LOGO)     Cat. #642130F



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