PRUDENTIAL MUNICIPAL SERIES FUND
24F-2NT, 1996-10-29
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             U.S. SECURITIES AND EXCHANGE COMMISSION
                     Washington, D.C.  20549

                            FORM 24F-2
                 Annual Notice of Securities Sold
                      Pursuant to Rule 24f-2

     Read instructions at end of Form before preparing Form.
                      Please print or type.



          1.   Name and address of issuer: Prudential Municipal Series Fund, One
          Seaport Plaza, New York, New York  10292.

          2.    Name of each series or class of funds for which this  notice  is
          filed:   The Fund offered three classes of shares designated Class  A,
          Class B and Class C during the fiscal year ended August 31, 1996.

          3.   Investment Company Act File Number:  811-4023.
               Securities Act File Number: 2-91216.

          4.    Last  day of fiscal year for which this notice is filed:  August
          31, 1996.

          5.    Check box if this notice is being filed more than 180 days after
          the  close  of  the  issuer's fiscal year for  purposes  of  reporting
          securities  sold  after  the  close of  the  fiscal  year  but  before
          termination of the issuer's  24f-2 declaration:
                                                       [ ]

          6.    Date  of  termination of issuer's declaration under  rule   24f-
          2(a)(1), if applicable (see instruction A.6):

          7.   Number and amount of securities of the same class or series which
          had  been  registered  under the Securities Act  of  1933  other  than
          pursuant  to  rule  24f-2 in a prior fiscal year, but  which  remained
          unsold at the beginning of the fiscal year: 5,263,925/$44,170,914.

          8.   Number and amount of securities registered during the fiscal year
          other than pursuant to rule 24f-2: 9,212,919/$85,772,277.

          9.    Number  and aggregate sale price of securities sold during   the
          fiscal year: 2,374,188,584/$2,445,689,944.

    10.   Number  and aggregate sale price of securities sold during  the fiscal
          year  in  reliance  upon registration pursuant to rule  24f-2:  2,374,
          188,584/$2,445,689,944.

    11.   Number and aggregate sale price of securities issued during the fiscal
          year  in  connection with dividend reinvestment plans,  if  applicable
          (see instruction B.7): 22,424,468/$60,167,572.

    12.   Calculation of registration fee:

         (i) Aggregate sale price of securities
             sold during the fiscal year in
             reliance on rule 24f-2 (from item 10):  $2,445,689,944

        (ii) Aggregate price of shares issued in
             connection with dividend reinvestment
             plans (from item 11, if applicable):    +   60,167,572

       (iii) Aggregate price of shares redeemed or
             repurchased during the fiscal year
             (if applicable):                        -2,585,604,803

        (iv) Aggregate price of shares redeemed or
             repurchased and previously applied
             as a reduction to filing fees
             pursuant to rule 24e-2
             (if applicable):                        +          -0-

         (v) Net aggregate price of securities
             sold and issued during the fiscal
             year in reliance of rule 24f-2
             [line (i), plus line (ii), less
             line (iii), plus line (iv)]
             (if applicable):                                   -0-

        (vi) Multiplier prescribed by section
             6(b) of the Securities Act of 1933
             or other applicable law or regulation
             (see instruction C.6):                  x       1/3300

       (vii) Fee due [line (i) or line (v)
             multiplied by line (vi)]:                           -0-

Instructions:       Issuers should complete lines (ii), (iii), (iv) and (v) only
                    if the form is being filed within 60 days after the close of
                    the issuer's fiscal year.  See Instruction C.3.

    13.   Check  box  if  fees  are being remitted to the Commission's   lockbox
          depository  as  described in section 3a of the Commission's  Rules  of
          Informal and Other Procedures (17 CFR 202.3a).
                                                  [ ]

             Date of mailing or wire transfer of filing fees to the Commission's
          lockbox depository: October   , 1996.

                            SIGNATURES

     This  report has been signed below by the following persons on  behalf
     of the issuer and in the capacities and on the dates indicated.

                                   /s/ S. Jane Rose
                                   By (S. Jane Rose, Secretary)


     Date October 23, 1996














MSF1096.NOT









                                   October 23, 1996


Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C. 20549

          RE:  Prudential Municipal Series Fund
               File Nos. 2-91216 and 811-4023

Ladies and Gentlemen:

           On  behalf  of Prudential Municipal Series Fund enclosed  for  filing
under the Investment Company Act of 1940 are:

          (1)  One copy of the Rule 24f-2 Notice; and

          (2)  Opinion of counsel to the Fund.

          These documents have been filed using the EDGAR system.

           If  you have any questions relating to the foregoing, please call the
undersigned at (212) 214-1248.

          Please acknowledge receipt via EDGAR.


                                   Very truly yours,

                                   /s/ Deborah A. Docs /s/ Deborah A. Docs
DAD:lr                             Deborah A. Docs
Enclosures                         Assistant Secretary


cc:  Paul H. Dykstra
     (Gardner, Carton & Douglas)

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                                   Boston
                                   October 28, 1996


Prudential Mutual Fund
  Management, Inc.
One Seaport Plaza
New York, N.Y.  10292

               Re:  Prudential Municipal Series Fund -
                      Rule 24f-2 Notice for Fiscal
                      Year Ended August 31, 1996

Ladies and Gentlemen:

     You have requested our opinion as to certain matters of Massachusetts law
in connection
with the Notice pursuant to Rule 24f-2 (the "Notice") under the Investment
Company Act of 1940,
as amended, being filed for the fiscal year ended August 31, 1996 by Prudential
Municipal Series
Fund (formerly "Prudential-Bache Municipal Series Fund"), a trust with
transferable shares (the
"Fund"), established under Massachusetts law pursuant to a Declaration of Trust
dated May 18,
1984 (the "Original Declaration"), which, as theretofore amended, was amended
and restated by an
Amended and Restated Declaration of Trust (the "Amended and Restated
Declaration") dated
August 17, 1994, and supplemented by an Amended Certificate of Designation dated
December 1,
1995 (the Original Declaration, as so amended, restated and supplemented, is
hereinafter referred
to as the "Declaration").

     We have acted as counsel to the Fund in connection with the execution and
delivery of the
Amended and Restated Declaration and such Amended Certificate of Designation,
and in connection
therewith we have examined and are familiar with the Original Declaration and
the instruments
amending, restating and supplementing the same, and the actions taken by the
Trustees of the Fund
to organize the Fund and to authorize the issuance and sale of shares of
beneficial interest, par value
$.01 per share (the "Shares"), of the several series authorized by the
Declaration.  For purposes of
this opinion, we also have examined and are familiar with the Declaration, the
Bylaws of the Fund,
the Notice, the most recent forms of the Prospectus and the Statement of
Additional Information
included in the Fund's Registration Statement on Form N-1A, certificates of
Trustees and officers
of the Fund and of public officials as to other matters of fact, and such
questions of law and fact, as
we have considered necessary or appropriate for purposes of the opinions
expressed herein.  We
have assumed the genuineness of the signatures on, and the authenticity of, all
documents furnished
to us, and the conformity to the originals of documents submitted to us as
copies, which we have not
independently verified.

     Based upon and subject to the foregoing, we hereby advise you that, in our
opinion, under
Massachusetts law:

     1.  The Fund is validly existing as a trust with transferable shares of the
type
    commonly called a Massachusetts business trust.

     2.  The Fund was authorized to issue an unlimited number of Shares; the
Shares of
    each series issued by the Fund during the fiscal year ended August 31, 1996
(the "Issued
    Shares") were duly and validly authorized by all requisite action of the
Trustees of the Fund,
    and no action of shareholders of the Fund was required in such connection.

     3.  The Issued Shares were validly and legally issued by the Fund, and all
of the
    Issued Shares which remained outstanding at August 31, 1996, were fully paid
and
    nonassessable by the Fund.

     With respect to the opinion stated in paragraph 3 above, we wish to point
out that the share-
holders of a Massachusetts business trust may under some circumstances be
subject to assessment
at the instance of creditors to pay the obligations of such trust in the event
that its assets are
insufficient for the purpose.

     This letter expresses our opinions as to the provisions of the Declaration
and the laws of
Massachusetts applying to business trusts generally, but does not extend to the
Massachusetts
Securities Act, or to federal securities or other laws.

     We hereby consent to the filing of this letter with the Securities and
Exchange Commission
as an exhibit to the Notice, but we do not thereby concede that we come within
the category of per-
sons whose consent is required under Section 7 of the Securities Act of 1933, as
amended.

                                 Very truly yours,



                                 SULLIVAN & WORCESTER LLP


                Prudential Municipal Series Fund
               Assistant Treasurer's Certificate

    The   undersigned,  Treasurer  of  Prudential  Municipal  Series   Fund,   a

Massachusetts business trust (the "Company"), does hereby certify as follows:

       1.  For  the  fiscal  year  ended August 31,  1996,  the  Company  issued

       2,396,613,052 shares of Beneficial Interest (including 22,424,468  shares

       issued  upon  reinvestment of dividends), $.01 par value,  consisting  of

       2,931,429  Class A shares and 7,392,761 Class B shares and 366,209  Class

       C  shares  and  1,141,349,118, 692,631,853, 286,441,119  and  265,500,563

       shares  of the New York Money Market Series, the New Jersey Money  Market

       Series,  the Connecticut Money Market Series and the Massachusetts  Money

       Market Series.

       2.  In  respect  of the issuance of such 2,396,613,052 shares  (including

       22,424,468  shares issued upon reinvestment of dividends), consisting  of

       2,931,429  Class A shares and 7,392,761 Class B shares and 366,209  Class

       C  shares  and  1,141,349,118, 692,631,853, 286,441,119  and  265,500,563

       shares  of the New York Money Market Series, the New Jersey Money  Market

       Series,  the Connecticut Money Market Series and the Massachusetts  Money

       Market  Series,  the Fund received cash consideration  of  $2,505,857,516

       (including   $60,167,572  received  upon  reinvestment   of   dividends),

       consisting of $32,833,538 for Class A shares and $83,034,004 for Class  B

       shares  and $4,067,321 for Class C shares and $2,385,922,653 for the  New

       York  Money  Market  Series,  the New Jersey  Money  Market  Series,  the

       Connecticut  Money  Market  Series and  the  Massachusetts  Money  Market

       Series.

       3.   With   respect  to  each  share  issued,  the  Fund  received   cash

       consideration  not less than the net asset value per share  on  the  date

       issued and not less than $.01.

       4.  To  the  best  of  my knowledge and belief, the Company  is  in  good

       standing in the Commonwealth of Massachusetts.

   In Witness Whereof, I have hereunto signed my name as Assistant Treasurer  of

the Company.

Date:  October   , 1996

(SEAL)                             /s/ Grace Torres
                                   Grace Torres








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