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<PAGE> PAGE 7
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<PAGE> PAGE 10
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<PAGE> PAGE 11
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<PAGE> PAGE 12
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<PAGE> PAGE 13
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<PAGE> PAGE 14
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<PAGE> PAGE 15
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<PAGE> PAGE 16
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<PAGE> PAGE 18
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<PAGE> PAGE 20
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<PAGE> PAGE 21
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<PAGE> PAGE 22
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<PAGE> PAGE 23
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<PAGE> PAGE 24
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<PAGE> PAGE 25
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<PAGE> PAGE 26
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<PAGE> PAGE 27
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<PAGE> PAGE 28
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<PAGE> PAGE 29
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<PAGE> PAGE 30
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<PAGE> PAGE 31
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<PAGE> PAGE 32
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<PAGE> PAGE 33
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<PAGE> PAGE 34
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<PAGE> PAGE 35
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<PAGE> PAGE 36
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<PAGE> PAGE 37
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<PAGE> PAGE 38
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<PAGE> PAGE 39
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<PAGE> PAGE 40
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<PAGE> PAGE 41
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057 001000 N
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<PAGE> PAGE 42
062 E001000 101.6
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063 B001000 0.0
064 A001000 Y
064 B001000 N
066 A001000 N
067 001000 N
068 A001000 N
068 B001000 N
069 001000 N
070 A011000 Y
070 A021000 N
070 B011000 N
070 B021000 N
070 C011000 Y
070 C021000 N
070 D011000 N
070 D021000 N
070 E011000 N
070 E021000 N
070 F011000 N
070 F021000 N
070 G011000 N
070 G021000 N
070 H011000 N
070 H021000 N
070 I011000 N
070 I021000 N
070 J011000 Y
070 J021000 Y
070 K011000 Y
070 K021000 N
070 L011000 N
070 L021000 N
070 M011000 N
070 M021000 N
070 N011000 N
070 N021000 N
<PAGE> PAGE 43
070 O011000 Y
070 O021000 Y
070 P011000 Y
070 P021000 Y
070 Q011000 N
070 Q021000 N
070 R011000 N
070 R021000 N
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074 B001000 0
<PAGE> PAGE 44
074 C001000 96417
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028 A011100 10071
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<PAGE> PAGE 45
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044 001100 0
055 A001100 Y
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<PAGE> PAGE 46
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064 A001100 Y
064 B001100 N
066 A001100 N
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068 A001100 N
068 B001100 N
069 001100 N
070 A011100 Y
070 A021100 N
070 B011100 N
070 B021100 N
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070 D021100 N
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070 F021100 N
070 G011100 N
070 G021100 N
070 H011100 N
070 H021100 N
070 I011100 N
070 I021100 N
070 J011100 Y
070 J021100 Y
070 K011100 Y
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070 L011100 N
070 L021100 N
070 M011100 N
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<PAGE> PAGE 47
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<PAGE> PAGE 48
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<PAGE> PAGE 49
028 H001200 0
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<PAGE> PAGE 50
064 A001200 Y
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068 A001200 N
068 B001200 N
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070 B011200 N
070 B021200 N
070 C011200 Y
070 C021200 N
070 D011200 N
070 D021200 N
070 E011200 N
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070 F021200 N
070 G011200 N
070 G021200 N
070 H011200 N
070 H021200 N
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070 L021200 N
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<PAGE> PAGE 51
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<PAGE> PAGE 52
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074 Y001200 0
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075 B001200 0
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<PAGE> PAGE 53
033 001300 0
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<PAGE> PAGE 54
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070 C021300 N
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070 G011300 N
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<PAGE> PAGE 55
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<PAGE> PAGE 56
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038 002000 0
SIGNATURE GRACE C. TORRES
TITLE TREASURER
For the fiscal year ended (a) 8/31/99
File number (c) 811-4023
SUB-ITEM 77-0
EXHIBITS
Transactions Effected Pursuant to Rule 10f-3
I. NY Series
1. Name of Issuer:
New York State Mortgage Agency
2. Date of Purchase
06/16/1999
3. Number of Securities Purchased
50,000
4. Dollar Amount of Purchase
$5,000,000
5. Price Per Unit
$100.00
6. Name(s) of Underwriter(s) or Dealer(s)
From whom Purchased
Bear Sterns & Co., Inc.
7. Other Members of the Underwriting Syndicate
See Exhibit A
EXHIBIT A
UNDERWRITER
Advest, Inc. PaineWebber Incorporated
Bear, Stearns & Co. Inc. Prudential Securities Incorporated
BNY Capital Markets, Inc. Ramirez & Co., Inc.
CIBC World Markets Raymond James & Associates, Inc.
Dain Rauscher Inc. Roosevelt & Cross, Inc.
First Albany Corp. Salomon Smith Barney
Fleet Securities Inc.
George K. Baum & Co.
Goldman, Sachs & Co.
Greenwich Partners, Inc.
J.P. Morgan Securities, Inc.
Lehman Brothers
Merrill Lynch & Co.
Morgan Stanley & Co., Inc.
M. R. Beal & Company
Report of Independent Accountants
To the Shareholders and Board of Trustees of
Prudential Municipal Series Fund
In planning and performing our audits of the financial
statements of Prudential Municipal Series Fund (the "Fund",
consisting of Connecticut Money Market Series, Florida
Series, Massachusetts Money Market Series, Massachusetts
Series, New Jersey Money Market Series, New Jersey Series,
New York Money Market Series, New York Series, North
Carolina Series, Ohio Series and Pennsylvania Series) for
the year ended August 31, 1999, we considered their internal
control, including control activities for safeguarding
securities, in order to determine our auditing procedures
for the purpose of expressing our opinion on the financial
statements and to comply with the requirements of Form N-
SAR, not to provide assurance on internal control.
The management of the Fund is responsible for establishing
and maintaining internal control. In fulfilling this
responsibility, estimates and judgments by management are
required to assess the expected benefits and related costs
of controls. Generally, controls that are relevant to an
audit pertain to the entity's objective of preparing
financial statements for external purposes that are fairly
presented in conformity with generally accepted accounting
principles. Those controls include the safeguarding of
assets against unauthorized acquisition, use or disposition.
Because of inherent limitations in internal control, errors
or fraud may occur and not be detected. Also, projection of
any evaluation of internal control to future periods is
subject to the risk that it may become inadequate because of
changes in conditions or that the effectiveness of the
design and operation may deteriorate.
Our consideration of internal control would not necessarily
disclose all matters in internal control that might be
material weaknesses under standards established by the
American Institute of Certified Public Accountants. A
material weakness is a condition in which the design or
operation of one or more of the internal control components
does not reduce to a relatively low level the risk that
misstatements caused by error or fraud in amounts that would
be material in relation to the financial statements being
audited may occur and not be detected within a timely period
by employees in the normal course of performing their
assigned functions. However, we noted no matters involving
internal control and its operation, including controls for
safeguarding securities, that we consider to be material
weaknesses as defined above as of August 31, 1999.
This report is intended solely for the information and use
of management, the Board of Trustees of the Fund and the
Securities and Exchange Commission and is not intended to be
and should not be used by anyone other than these specified
parties.
PricewaterhouseCoopers LLP
New York, New York
October 15, 1999
To the Shareholders and Board of Trustees of
Prudential Municipal Series Fund
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 001
<NAME> CONNECTICUT MONEY MARKET SERIES
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 0
<INVESTMENTS-AT-VALUE> 83,102,050
<RECEIVABLES> 1,140,084
<ASSETS-OTHER> 816,138
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 801,908
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 1,181,631
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 83,074,460
<SHARES-COMMON-STOCK> 83,074,733
<SHARES-COMMON-PRIOR> 95,117,448
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 0
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 0
<NET-ASSETS> (178,192,181)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 2,708,796
<OTHER-INCOME> 0
<EXPENSES-NET> 693,894
<NET-INVESTMENT-INCOME> 2,014,902
<REALIZED-GAINS-CURRENT> 5,471
<APPREC-INCREASE-CURRENT> 0
<NET-CHANGE-FROM-OPS> 2,020,373
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (2,020,373)
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 311,218,175
<NUMBER-OF-SHARES-REDEEMED> (325,228,890)
<SHARES-REINVESTED> 1,968,000
<NET-CHANGE-IN-ASSETS> (12,042,715)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 0
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 438,720
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 671,635
<AVERAGE-NET-ASSETS> 87,744,000
<PER-SHARE-NAV-BEGIN> 1.00
<PER-SHARE-NII> 0.02
<PER-SHARE-GAIN-APPREC> 0.00
<PER-SHARE-DIVIDEND> (0.02)
<PER-SHARE-DISTRIBUTIONS> 0.00
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 1.00
<EXPENSE-RATIO> 0.82
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 001
<NAME> FLORIDA SERIES (CLASS A)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 105,762,409
<INVESTMENTS-AT-VALUE> 107,611,159
<RECEIVABLES> 1,929,194
<ASSETS-OTHER> 78,259
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 165,441
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 219,564
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 107,485,867
<SHARES-COMMON-STOCK> 10,734,007
<SHARES-COMMON-PRIOR> 8,200,226
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> (101,010)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 1,848,750
<NET-ASSETS> (18,934,233)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 6,586,317
<OTHER-INCOME> 0
<EXPENSES-NET> 1,162,233
<NET-INVESTMENT-INCOME> 5,424,084
<REALIZED-GAINS-CURRENT> 447,190
<APPREC-INCREASE-CURRENT> (6,574,512)
<NET-CHANGE-FROM-OPS> (703,238)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (5,424,084)
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> (22,709)
<NUMBER-OF-SHARES-SOLD> 13,296,170
<NUMBER-OF-SHARES-REDEEMED> (19,003,105)
<SHARES-REINVESTED> 2,387,979
<NET-CHANGE-IN-ASSETS> (9,468,987)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> (1,380,039)
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 586,541
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 1,158,891
<AVERAGE-NET-ASSETS> 84,810,000
<PER-SHARE-NAV-BEGIN> 10.74
<PER-SHARE-NII> 0.50
<PER-SHARE-GAIN-APPREC> (0.56)
<PER-SHARE-DIVIDEND> (0.50)
<PER-SHARE-DISTRIBUTIONS> 0.00
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 10.18
<EXPENSE-RATIO> 0.89
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 002
<NAME> FLORIDA SERIES (CLASS B)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 105,762,409
<INVESTMENTS-AT-VALUE> 107,611,159
<RECEIVABLES> 1,929,194
<ASSETS-OTHER> 78,259
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 165,441
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 219,564
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 107,485,867
<SHARES-COMMON-STOCK> 10,734,007
<SHARES-COMMON-PRIOR> 8,200,226
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> (101,010)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 1,848,750
<NET-ASSETS> (18,934,233)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 6,586,317
<OTHER-INCOME> 0
<EXPENSES-NET> 1,162,233
<NET-INVESTMENT-INCOME> 5,424,084
<REALIZED-GAINS-CURRENT> 447,190
<APPREC-INCREASE-CURRENT> (6,574,512)
<NET-CHANGE-FROM-OPS> (703,238)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (5,424,084)
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> (22,709)
<NUMBER-OF-SHARES-SOLD> 13,296,170
<NUMBER-OF-SHARES-REDEEMED> (19,003,105)
<SHARES-REINVESTED> 2,387,979
<NET-CHANGE-IN-ASSETS> (9,468,987)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> (1,380,039)
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 586,541
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 1,158,891
<AVERAGE-NET-ASSETS> 24,665,000
<PER-SHARE-NAV-BEGIN> 10.74
<PER-SHARE-NII> 0.47
<PER-SHARE-GAIN-APPREC> (0.56)
<PER-SHARE-DIVIDEND> (0.47)
<PER-SHARE-DISTRIBUTIONS> 0.00
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 10.18
<EXPENSE-RATIO> 1.19
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 003
<NAME> FLORIDA SERIES (CLASS C)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 105,762,409
<INVESTMENTS-AT-VALUE> 107,611,159
<RECEIVABLES> 1,929,194
<ASSETS-OTHER> 78,259
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<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 165,441
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 219,564
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 107,485,867
<SHARES-COMMON-STOCK> 10,734,007
<SHARES-COMMON-PRIOR> 8,200,226
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> (101,010)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 1,848,750
<NET-ASSETS> (18,934,233)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 6,586,317
<OTHER-INCOME> 0
<EXPENSES-NET> 1,162,233
<NET-INVESTMENT-INCOME> 5,424,084
<REALIZED-GAINS-CURRENT> 447,190
<APPREC-INCREASE-CURRENT> (6,574,512)
<NET-CHANGE-FROM-OPS> (703,238)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (5,424,084)
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> (22,709)
<NUMBER-OF-SHARES-SOLD> 13,296,170
<NUMBER-OF-SHARES-REDEEMED> (19,003,105)
<SHARES-REINVESTED> 2,387,979
<NET-CHANGE-IN-ASSETS> (9,468,987)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> (1,380,039)
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 586,541
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 1,158,891
<AVERAGE-NET-ASSETS> 7,420,000
<PER-SHARE-NAV-BEGIN> 10.74
<PER-SHARE-NII> 0.44
<PER-SHARE-GAIN-APPREC> (0.56)
<PER-SHARE-DIVIDEND> (0.44)
<PER-SHARE-DISTRIBUTIONS> 0.00
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 10.18
<EXPENSE-RATIO> 1.44
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 004
<NAME> FLORIDA SERIES (CLASS Z)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 105762409
<INVESTMENTS-AT-VALUE> 107611159
<RECEIVABLES> 1929194
<ASSETS-OTHER> 78259
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 165441
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 219564
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 107485867
<SHARES-COMMON-STOCK> 10734007
<SHARES-COMMON-PRIOR> 8200226
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> -101010
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 1848750
<NET-ASSETS> -18934233
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 6586317
<OTHER-INCOME> 0
<EXPENSES-NET> 1162233
<NET-INVESTMENT-INCOME> 5424084
<REALIZED-GAINS-CURRENT> 447190
<APPREC-INCREASE-CURRENT> -6574512
<NET-CHANGE-FROM-OPS> -703238
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> -5424084
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> -22709
<NUMBER-OF-SHARES-SOLD> 13296170
<NUMBER-OF-SHARES-REDEEMED> -19003105
<SHARES-REINVESTED> 2387979
<NET-CHANGE-IN-ASSETS> -9468987
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> -1380039
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 586541
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 1158891
<AVERAGE-NET-ASSETS> 413,000
<PER-SHARE-NAV-BEGIN> 10.73
<PER-SHARE-NII> 0.52
<PER-SHARE-GAIN-APPREC> -0.56
<PER-SHARE-DIVIDEND> -0.52
<PER-SHARE-DISTRIBUTIONS> 0
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 10.17
<EXPENSE-RATIO> 0.69
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 001
<NAME> MASSACHUSETTS MONEY MARKET SERIES
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 0
<INVESTMENTS-AT-VALUE> 55,988,967
<RECEIVABLES> 646,576
<ASSETS-OTHER> 1,323
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 1,043,337
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 90,018
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 55,503,531
<SHARES-COMMON-STOCK> 55,503,531
<SHARES-COMMON-PRIOR> 58,541,853
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 0
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 0
<NET-ASSETS> (114,045,384)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 1,877,779
<OTHER-INCOME> 0
<EXPENSES-NET> 513,141
<NET-INVESTMENT-INCOME> 1,364,638
<REALIZED-GAINS-CURRENT> 0
<APPREC-INCREASE-CURRENT> 0
<NET-CHANGE-FROM-OPS> 1,364,638
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (1,364,638)
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 174,293,713
<NUMBER-OF-SHARES-REDEEMED> (182,580,621)
<SHARES-REINVESTED> 1,330,047
<NET-CHANGE-IN-ASSETS> (6,956,861)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 0
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 293,272
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 509,373
<AVERAGE-NET-ASSETS> 58,654,000
<PER-SHARE-NAV-BEGIN> 1.00
<PER-SHARE-NII> 0.02
<PER-SHARE-GAIN-APPREC> 0.00
<PER-SHARE-DIVIDEND> (0.02)
<PER-SHARE-DISTRIBUTIONS> 0.00
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 1.00
<EXPENSE-RATIO> 0.88
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 001
<NAME> MASSACHUSETTS SERIES (CLASS A)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 38,485,652
<INVESTMENTS-AT-VALUE> 40,256,674
<RECEIVABLES> 591,774
<ASSETS-OTHER> 6,107
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 0
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 138,129
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 39,143,838
<SHARES-COMMON-STOCK> 3,672,259
<SHARES-COMMON-PRIOR> 3,816,232
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> (198,434)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 1,771,022
<NET-ASSETS> (7,488,491)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 2,624,994
<OTHER-INCOME> 0
<EXPENSES-NET> 555,350
<NET-INVESTMENT-INCOME> 2,069,644
<REALIZED-GAINS-CURRENT> (12,605)
<APPREC-INCREASE-CURRENT> (2,713,045)
<NET-CHANGE-FROM-OPS> (656,006)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (2,069,644)
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> (441,704)
<NUMBER-OF-SHARES-SOLD> 7,872,665
<NUMBER-OF-SHARES-REDEEMED> (10,782,045)
<SHARES-REINVESTED> 1,388,189
<NET-CHANGE-IN-ASSETS> (4,688,545)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 0
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 228,953
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 555,116
<AVERAGE-NET-ASSETS> 30,705,000
<PER-SHARE-NAV-BEGIN> 11.90
<PER-SHARE-NII> 0.53
<PER-SHARE-GAIN-APPREC> (0.70)
<PER-SHARE-DIVIDEND> (0.53)
<PER-SHARE-DISTRIBUTIONS> (0.11)
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 11.09
<EXPENSE-RATIO> 1.11
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 002
<NAME> MASSACHUSETTS SERIES (CLASS B)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 38,485,652
<INVESTMENTS-AT-VALUE> 40,256,674
<RECEIVABLES> 591,774
<ASSETS-OTHER> 6,107
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 0
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 138,129
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 39,143,838
<SHARES-COMMON-STOCK> 3,672,259
<SHARES-COMMON-PRIOR> 3,816,232
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> (198,434)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 1,771,022
<NET-ASSETS> (7,488,491)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 2,624,994
<OTHER-INCOME> 0
<EXPENSES-NET> 555,350
<NET-INVESTMENT-INCOME> 2,069,644
<REALIZED-GAINS-CURRENT> (12,605)
<APPREC-INCREASE-CURRENT> (2,713,045)
<NET-CHANGE-FROM-OPS> (656,006)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (2,069,644)
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> (441,704)
<NUMBER-OF-SHARES-SOLD> 7,872,665
<NUMBER-OF-SHARES-REDEEMED> (10,782,045)
<SHARES-REINVESTED> 1,388,189
<NET-CHANGE-IN-ASSETS> (4,688,545)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 0
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 228,953
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 555,116
<AVERAGE-NET-ASSETS> 14,837,000
<PER-SHARE-NAV-BEGIN> 11.89
<PER-SHARE-NII> 0.50
<PER-SHARE-GAIN-APPREC> (0.70)
<PER-SHARE-DIVIDEND> (0.50)
<PER-SHARE-DISTRIBUTIONS> (0.11)
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 11.08
<EXPENSE-RATIO> 1.41
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 003
<NAME> MASSACHUSETTS SERIES (CLASS C)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 38,485,652
<INVESTMENTS-AT-VALUE> 40,256,674
<RECEIVABLES> 591,774
<ASSETS-OTHER> 6,107
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 0
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 138,129
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 39,143,838
<SHARES-COMMON-STOCK> 3,672,259
<SHARES-COMMON-PRIOR> 3,816,232
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> (198,434)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 1,771,022
<NET-ASSETS> (7,488,491)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 2,624,994
<OTHER-INCOME> 0
<EXPENSES-NET> 555,350
<NET-INVESTMENT-INCOME> 2,069,644
<REALIZED-GAINS-CURRENT> (12,605)
<APPREC-INCREASE-CURRENT> (2,713,045)
<NET-CHANGE-FROM-OPS> (656,006)
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<DISTRIBUTIONS-OF-INCOME> (2,069,644)
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> (441,704)
<NUMBER-OF-SHARES-SOLD> 7,872,665
<NUMBER-OF-SHARES-REDEEMED> (10,782,045)
<SHARES-REINVESTED> 1,388,189
<NET-CHANGE-IN-ASSETS> (4,688,545)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 0
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 228,953
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 555,116
<AVERAGE-NET-ASSETS> 196,000
<PER-SHARE-NAV-BEGIN> 11.89
<PER-SHARE-NII> 0.47
<PER-SHARE-GAIN-APPREC> (0.70)
<PER-SHARE-DIVIDEND> (0.47)
<PER-SHARE-DISTRIBUTIONS> (0.11)
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 11.08
<EXPENSE-RATIO> 1.66
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 004
<NAME> MASSACHUSETTS SERIES (CLASS Z)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 38485652
<INVESTMENTS-AT-VALUE> 40256674
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<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 138129
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 39143838
<SHARES-COMMON-STOCK> 3672259
<SHARES-COMMON-PRIOR> 3816232
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> -198434
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 1771022
<NET-ASSETS> -7488491
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 2624994
<OTHER-INCOME> 0
<EXPENSES-NET> 555350
<NET-INVESTMENT-INCOME> 2069644
<REALIZED-GAINS-CURRENT> -12605
<APPREC-INCREASE-CURRENT> -2713045
<NET-CHANGE-FROM-OPS> -656006
<EQUALIZATION> 0
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<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> -441704
<NUMBER-OF-SHARES-SOLD> 7872665
<NUMBER-OF-SHARES-REDEEMED> -10782045
<SHARES-REINVESTED> 1388189
<NET-CHANGE-IN-ASSETS> -4688545
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 0
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 228953
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 555116
<AVERAGE-NET-ASSETS> 198 **
<PER-SHARE-NAV-BEGIN> 11.89
<PER-SHARE-NII> 0.56
<PER-SHARE-GAIN-APPREC> -0.7
<PER-SHARE-DIVIDEND> -0.56
<PER-SHARE-DISTRIBUTIONS> -0.11
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 11.08
<EXPENSE-RATIO> 0.91
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0
<**Amounts are actual and not rounded to the nearest thousand.>
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> MUNI - NORTH CAROLINA
<SERIES>
<NUMBER> 001
<NAME> MUNI - NORTH CAROLINA (CLASS A)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 44,198,068
<INVESTMENTS-AT-VALUE> 45,343,910
<RECEIVABLES> 645,533
<ASSETS-OTHER> 149,856
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 0
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 150,982
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 44,824,265
<SHARES-COMMON-STOCK> 4,208,794
<SHARES-COMMON-PRIOR> 4,396,347
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 18,210
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 1,145,842
<NET-ASSETS> (8,605,141)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 2,819,431
<OTHER-INCOME> 0
<EXPENSES-NET> 577,755
<NET-INVESTMENT-INCOME> 2,241,676
<REALIZED-GAINS-CURRENT> 58,888
<APPREC-INCREASE-CURRENT> (3,120,844)
<NET-CHANGE-FROM-OPS> (820,280)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (2,241,676)
<DISTRIBUTIONS-OF-GAINS> (253,943)
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 3,818,192
<NUMBER-OF-SHARES-REDEEMED> (7,739,135)
<SHARES-REINVESTED> 1,320,522
<NET-CHANGE-IN-ASSETS> (5,916,320)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> (8,339)
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 251,728
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 577,496
<AVERAGE-NET-ASSETS> 30,621,000
<PER-SHARE-NAV-BEGIN> 11.69
<PER-SHARE-NII> 0.53
<PER-SHARE-GAIN-APPREC> (0.71)
<PER-SHARE-DIVIDEND> (0.53)
<PER-SHARE-DISTRIBUTIONS> 0.00
<RETURNS-OF-CAPITAL> (0.06)
<PER-SHARE-NAV-END> 10.92
<EXPENSE-RATIO> 1.03
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> MUNI - NORTH CAROLINA
<SERIES>
<NUMBER> 002
<NAME> MUNI - NORTH CAROLINA (CLASS B)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 44,198,068
<INVESTMENTS-AT-VALUE> 45,343,910
<RECEIVABLES> 645,533
<ASSETS-OTHER> 149,856
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 0
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 150,982
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 44,824,265
<SHARES-COMMON-STOCK> 4,208,794
<SHARES-COMMON-PRIOR> 4,396,347
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 18,210
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 1,145,842
<NET-ASSETS> (8,605,141)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 2,819,431
<OTHER-INCOME> 0
<EXPENSES-NET> 577,755
<NET-INVESTMENT-INCOME> 2,241,676
<REALIZED-GAINS-CURRENT> 58,888
<APPREC-INCREASE-CURRENT> (3,120,844)
<NET-CHANGE-FROM-OPS> (820,280)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (2,241,676)
<DISTRIBUTIONS-OF-GAINS> (253,943)
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 3,818,192
<NUMBER-OF-SHARES-REDEEMED> (7,739,135)
<SHARES-REINVESTED> 1,320,522
<NET-CHANGE-IN-ASSETS> (5,916,320)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> (8,339)
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 251,728
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 577,496
<AVERAGE-NET-ASSETS> 19,695,000
<PER-SHARE-NAV-BEGIN> 11.69
<PER-SHARE-NII> 0.49
<PER-SHARE-GAIN-APPREC> (0.70)
<PER-SHARE-DIVIDEND> (0.49)
<PER-SHARE-DISTRIBUTIONS> 0.00
<RETURNS-OF-CAPITAL> (0.06)
<PER-SHARE-NAV-END> 10.93
<EXPENSE-RATIO> 1.33
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> MUNI - NORTH CAROLINA
<SERIES>
<NUMBER> 003
<NAME> MUNI - NORTH CAROLINA (CLASS C)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 44,198,068
<INVESTMENTS-AT-VALUE> 45,343,910
<RECEIVABLES> 645,533
<ASSETS-OTHER> 149,856
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 0
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 150,982
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 44,824,265
<SHARES-COMMON-STOCK> 4,208,794
<SHARES-COMMON-PRIOR> 4,396,347
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 18,210
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 1,145,842
<NET-ASSETS> (8,605,141)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 2,819,431
<OTHER-INCOME> 0
<EXPENSES-NET> 577,755
<NET-INVESTMENT-INCOME> 2,241,676
<REALIZED-GAINS-CURRENT> 58,888
<APPREC-INCREASE-CURRENT> (3,120,844)
<NET-CHANGE-FROM-OPS> (820,280)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (2,241,676)
<DISTRIBUTIONS-OF-GAINS> (253,943)
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 3,818,192
<NUMBER-OF-SHARES-REDEEMED> (7,739,135)
<SHARES-REINVESTED> 1,320,522
<NET-CHANGE-IN-ASSETS> (5,916,320)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> (8,339)
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 251,728
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 577,496
<AVERAGE-NET-ASSETS> 30,000
<PER-SHARE-NAV-BEGIN> 11.69
<PER-SHARE-NII> 0.46
<PER-SHARE-GAIN-APPREC> (0.70)
<PER-SHARE-DIVIDEND> (0.46)
<PER-SHARE-DISTRIBUTIONS> 0.00
<RETURNS-OF-CAPITAL> (0.06)
<PER-SHARE-NAV-END> 10.93
<EXPENSE-RATIO> 1.58
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> MUNI - NORTH CAROLINA
<SERIES>
<NUMBER> 004
<NAME> MUNI - NORTH CAROLINA (CLASS Z)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 44,198,068
<INVESTMENTS-AT-VALUE> 45,343,910
<RECEIVABLES> 645,533
<ASSETS-OTHER> 149,856
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 0
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 150,982
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 44,824,265
<SHARES-COMMON-STOCK> 4,208,794
<SHARES-COMMON-PRIOR> 4,396,347
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 18,210
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 1,145,842
<NET-ASSETS> (8,605,141)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 2,819,431
<OTHER-INCOME> 0
<EXPENSES-NET> 577,755
<NET-INVESTMENT-INCOME> 2,241,676
<REALIZED-GAINS-CURRENT> 58,888
<APPREC-INCREASE-CURRENT> (3,120,844)
<NET-CHANGE-FROM-OPS> (820,280)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (2,241,676)
<DISTRIBUTIONS-OF-GAINS> (253,943)
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 3,818,192
<NUMBER-OF-SHARES-REDEEMED> (7,739,135)
<SHARES-REINVESTED> 1,320,522
<NET-CHANGE-IN-ASSETS> (5,916,320)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> (8,339)
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 251,728
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 577,496
<AVERAGE-NET-ASSETS> 0
<PER-SHARE-NAV-BEGIN> 0.00
<PER-SHARE-NII> 0.00
<PER-SHARE-GAIN-APPREC> 0.00
<PER-SHARE-DIVIDEND> 0.00
<PER-SHARE-DISTRIBUTIONS> 0.00
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 0.00
<EXPENSE-RATIO> 0.00
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 001
<NAME> NEW JERSEY MONEY MARKET FUND
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 0
<INVESTMENTS-AT-VALUE> 203,956,759
<RECEIVABLES> 5,742,749
<ASSETS-OTHER> 2,020,019
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 2,825,000
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 1,890,297
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 207,004,230
<SHARES-COMMON-STOCK> 207,004,230
<SHARES-COMMON-PRIOR> 214,423,588
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 0
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 0
<NET-ASSETS> (421,427,818)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 6,687,140
<OTHER-INCOME> 0
<EXPENSES-NET> 1,477,339
<NET-INVESTMENT-INCOME> 5,209,801
<REALIZED-GAINS-CURRENT> 0
<APPREC-INCREASE-CURRENT> 0
<NET-CHANGE-FROM-OPS> 5,209,801
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> 0
<DISTRIBUTIONS-OF-GAINS> (5,209,801)
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 772,444,020
<NUMBER-OF-SHARES-REDEEMED> (771,438,504)
<SHARES-REINVESTED> 5,083,846
<NET-CHANGE-IN-ASSETS> 6,089,362
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 0
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 1,047,394
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 1,451,560
<AVERAGE-NET-ASSETS> 209,479,000
<PER-SHARE-NAV-BEGIN> 1.00
<PER-SHARE-NII> 0.03
<PER-SHARE-GAIN-APPREC> 0.00
<PER-SHARE-DIVIDEND> (0.03)
<PER-SHARE-DISTRIBUTIONS> 0.00
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 1.00
<EXPENSE-RATIO> 0.72
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 001
<NAME> NEW JERSEY SERIES (CLASS A)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 203,711,726
<INVESTMENTS-AT-VALUE> 209,220,874
<RECEIVABLES> 2,665,946
<ASSETS-OTHER> 45,319
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 5,931,645
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 823,023
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 198,776,431
<SHARES-COMMON-STOCK> 19,226,121
<SHARES-COMMON-PRIOR> 20,570,402
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 891,892
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 5,509,148
<NET-ASSETS> (39,796,523)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 12,309,676
<OTHER-INCOME> 0
<EXPENSES-NET> 2,186,755
<NET-INVESTMENT-INCOME> 10,122,921
<REALIZED-GAINS-CURRENT> 1,234,336
<APPREC-INCREASE-CURRENT> (12,090,901)
<NET-CHANGE-FROM-OPS> (733,644)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (10,122,921)
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> (1,742,285)
<NUMBER-OF-SHARES-SOLD> 20,755,452
<NUMBER-OF-SHARES-REDEEMED> (42,677,795)
<SHARES-REINVESTED> 7,062,891
<NET-CHANGE-IN-ASSETS> (27,458,302)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 1,399,841
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 1,118,938
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 2,185,082
<AVERAGE-NET-ASSETS> 125,547,000
<PER-SHARE-NAV-BEGIN> 11.31
<PER-SHARE-NII> 0.52
<PER-SHARE-GAIN-APPREC> (0.55)
<PER-SHARE-DIVIDEND> (0.52)
<PER-SHARE-DISTRIBUTIONS> 0.00
<RETURNS-OF-CAPITAL> (0.09)
<PER-SHARE-NAV-END> 10.67
<EXPENSE-RATIO> 0.84
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 002
<NAME> NEW JERSEY SERIES (CLASS B)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 203,711,726
<INVESTMENTS-AT-VALUE> 209,220,874
<RECEIVABLES> 2,665,946
<ASSETS-OTHER> 45,319
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 5,931,645
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 823,023
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 198,776,431
<SHARES-COMMON-STOCK> 19,226,121
<SHARES-COMMON-PRIOR> 20,570,402
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 891,892
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 5,509,148
<NET-ASSETS> (39,796,523)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 12,309,676
<OTHER-INCOME> 0
<EXPENSES-NET> 2,186,755
<NET-INVESTMENT-INCOME> 10,122,921
<REALIZED-GAINS-CURRENT> 1,234,336
<APPREC-INCREASE-CURRENT> (12,090,901)
<NET-CHANGE-FROM-OPS> (733,644)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (10,122,921)
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> (1,742,285)
<NUMBER-OF-SHARES-SOLD> 20,755,452
<NUMBER-OF-SHARES-REDEEMED> (42,677,795)
<SHARES-REINVESTED> 7,062,891
<NET-CHANGE-IN-ASSETS> (27,458,302)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 1,399,841
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 1,118,938
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 2,185,082
<AVERAGE-NET-ASSETS> 96,542,000
<PER-SHARE-NAV-BEGIN> 11.31
<PER-SHARE-NII> 0.49
<PER-SHARE-GAIN-APPREC> (0.55)
<PER-SHARE-DIVIDEND> (0.49)
<PER-SHARE-DISTRIBUTIONS> 0.00
<RETURNS-OF-CAPITAL> (0.09)
<PER-SHARE-NAV-END> 10.67
<EXPENSE-RATIO> 1.14
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 003
<NAME> NEW JERSEY SERIES (CLASS C)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 203,711,726
<INVESTMENTS-AT-VALUE> 209,220,874
<RECEIVABLES> 2,665,946
<ASSETS-OTHER> 45,319
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 5,931,645
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 823,023
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 198,776,431
<SHARES-COMMON-STOCK> 19,226,121
<SHARES-COMMON-PRIOR> 20,570,402
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 891,892
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 5,509,148
<NET-ASSETS> (39,796,523)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 12,309,676
<OTHER-INCOME> 0
<EXPENSES-NET> 2,186,755
<NET-INVESTMENT-INCOME> 10,122,921
<REALIZED-GAINS-CURRENT> 1,234,336
<APPREC-INCREASE-CURRENT> (12,090,901)
<NET-CHANGE-FROM-OPS> (733,644)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (10,122,921)
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> (1,742,285)
<NUMBER-OF-SHARES-SOLD> 20,755,452
<NUMBER-OF-SHARES-REDEEMED> (42,677,795)
<SHARES-REINVESTED> 7,062,891
<NET-CHANGE-IN-ASSETS> (27,458,302)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 1,399,841
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 1,118,938
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 2,185,082
<AVERAGE-NET-ASSETS> 1,622,000
<PER-SHARE-NAV-BEGIN> 11.31
<PER-SHARE-NII> 0.46
<PER-SHARE-GAIN-APPREC> (0.55)
<PER-SHARE-DIVIDEND> (0.46)
<PER-SHARE-DISTRIBUTIONS> 0.00
<RETURNS-OF-CAPITAL> (0.09)
<PER-SHARE-NAV-END> 10.67
<EXPENSE-RATIO> 1.39
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 004
<NAME> NEW JERSEY SERIES (CLASS Z)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 203711726
<INVESTMENTS-AT-VALUE> 209220874
<RECEIVABLES> 2665946
<ASSETS-OTHER> 45319
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 5931645
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 823023
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 198776431
<SHARES-COMMON-STOCK> 19226121
<SHARES-COMMON-PRIOR> 20570402
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 891892
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 5509148
<NET-ASSETS> -39796523
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 12309676
<OTHER-INCOME> 0
<EXPENSES-NET> 2186755
<NET-INVESTMENT-INCOME> 10122921
<REALIZED-GAINS-CURRENT> 1234336
<APPREC-INCREASE-CURRENT> -12090901
<NET-CHANGE-FROM-OPS> -733644
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> -10122921
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> -1742285
<NUMBER-OF-SHARES-SOLD> 20755452
<NUMBER-OF-SHARES-REDEEMED> -42677795
<SHARES-REINVESTED> 7062891
<NET-CHANGE-IN-ASSETS> -27458302
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 1399841
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 1118938
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 2185082
<AVERAGE-NET-ASSETS> 198
<PER-SHARE-NAV-BEGIN> 11.32
<PER-SHARE-NII> 0.54
<PER-SHARE-GAIN-APPREC> -0.48
<PER-SHARE-DIVIDEND> -0.54
<PER-SHARE-DISTRIBUTIONS> 0
<RETURNS-OF-CAPITAL> -0.09
<PER-SHARE-NAV-END> 10.75
<EXPENSE-RATIO> 0.64
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0
<**AMOUNTS ARE ACTUAL AND NOT ROUNDED TO THE NEAREST THOUSAND.>
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 001
<NAME> NEW YORK MONEY MARKET SERIES
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 0
<INVESTMENTS-AT-VALUE> 338,306,725
<RECEIVABLES> 21,188,483
<ASSETS-OTHER> 3,025,747
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 3,566,562
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 398,425
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 358,555,968
<SHARES-COMMON-STOCK> 358,555,968
<SHARES-COMMON-PRIOR> 412,352,453
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 0
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 0
<NET-ASSETS> (770,908,421)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 11,838,887
<OTHER-INCOME> 0
<EXPENSES-NET> 2,604,043
<NET-INVESTMENT-INCOME> 9,234,844
<REALIZED-GAINS-CURRENT> 0
<APPREC-INCREASE-CURRENT> 0
<NET-CHANGE-FROM-OPS> 9,234,844
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (9,234,844)
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 1,191,546,021
<NUMBER-OF-SHARES-REDEEMED> (1,254,393,321)
<SHARES-REINVESTED> 9,050,815
<NET-CHANGE-IN-ASSETS> (53,796,485)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 0
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 1,878,249
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 2,595,685
<AVERAGE-NET-ASSETS> 375,650,000
<PER-SHARE-NAV-BEGIN> 1.00
<PER-SHARE-NII> 0.02
<PER-SHARE-GAIN-APPREC> 0.00
<PER-SHARE-DIVIDEND> (0.02)
<PER-SHARE-DISTRIBUTIONS> 0.00
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 1.00
<EXPENSE-RATIO> 0.70
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 001
<NAME> NEW YORK SERIES (CLASS A)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 243,211,090
<INVESTMENTS-AT-VALUE> 252,499,443
<RECEIVABLES> 3,605,588
<ASSETS-OTHER> 6,938
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 410,098
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 1,171,555
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 245,527,977
<SHARES-COMMON-STOCK> 22,139,491
<SHARES-COMMON-PRIOR> 22,785,976
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> (354,264)
<ACCUMULATED-NET-GAINS> 0
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 9,356,603
<NET-ASSETS> (44,925,467)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 15,247,938
<OTHER-INCOME> 0
<EXPENSES-NET> 2,549,640
<NET-INVESTMENT-INCOME> 12,698,298
<REALIZED-GAINS-CURRENT> 39,076
<APPREC-INCREASE-CURRENT> (15,675,222)
<NET-CHANGE-FROM-OPS> (2,937,848)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (12,698,298)
<DISTRIBUTIONS-OF-GAINS> (2,077,433)
<DISTRIBUTIONS-OTHER> (354,264)
<NUMBER-OF-SHARES-SOLD> 25,657,665
<NUMBER-OF-SHARES-REDEEMED> (40,612,658)
<SHARES-REINVESTED> 9,398,834
<NET-CHANGE-IN-ASSETS> (23,624,002)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 0
<OVERDISTRIB-NII-PRIOR> (256,091)
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 1,363,196
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 2,549,096
<AVERAGE-NET-ASSETS> 181,951,000
<PER-SHARE-NAV-BEGIN> 12.30
<PER-SHARE-NII> 0.57
<PER-SHARE-GAIN-APPREC> (0.69)
<PER-SHARE-DIVIDEND> (0.57)
<PER-SHARE-DISTRIBUTIONS> (0.11)
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 11.50
<EXPENSE-RATIO> 0.01
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 002
<NAME> NEW YORK SERIES (CLASS B)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 243,211,090
<INVESTMENTS-AT-VALUE> 252,499,443
<RECEIVABLES> 3,605,588
<ASSETS-OTHER> 6,938
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 410,098
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 1,171,555
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 245,527,977
<SHARES-COMMON-STOCK> 22,139,491
<SHARES-COMMON-PRIOR> 22,785,976
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> (354,264)
<ACCUMULATED-NET-GAINS> 0
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 9,356,603
<NET-ASSETS> (44,925,467)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 15,247,938
<OTHER-INCOME> 0
<EXPENSES-NET> 2,549,640
<NET-INVESTMENT-INCOME> 12,698,298
<REALIZED-GAINS-CURRENT> 39,076
<APPREC-INCREASE-CURRENT> (15,675,222)
<NET-CHANGE-FROM-OPS> (2,937,848)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (12,698,298)
<DISTRIBUTIONS-OF-GAINS> (2,077,433)
<DISTRIBUTIONS-OTHER> (354,264)
<NUMBER-OF-SHARES-SOLD> 25,657,665
<NUMBER-OF-SHARES-REDEEMED> (40,612,658)
<SHARES-REINVESTED> 9,398,834
<NET-CHANGE-IN-ASSETS> (23,624,002)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 0
<OVERDISTRIB-NII-PRIOR> (256,091)
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 1,363,196
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 2,549,096
<AVERAGE-NET-ASSETS> 88,626,000
<PER-SHARE-NAV-BEGIN> 12.30
<PER-SHARE-NII> 0.54
<PER-SHARE-GAIN-APPREC> (0.69)
<PER-SHARE-DIVIDEND> (0.54)
<PER-SHARE-DISTRIBUTIONS> (0.11)
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 11.50
<EXPENSE-RATIO> 1.13
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 003
<NAME> NEW YORK SERIES (CLASS C)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 243,211,090
<INVESTMENTS-AT-VALUE> 252,499,443
<RECEIVABLES> 3,605,588
<ASSETS-OTHER> 6,938
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 410,098
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 1,171,555
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 245,527,977
<SHARES-COMMON-STOCK> 22,139,491
<SHARES-COMMON-PRIOR> 22,785,976
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> (354,264)
<ACCUMULATED-NET-GAINS> 0
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 9,356,603
<NET-ASSETS> (44,925,467)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 15,247,938
<OTHER-INCOME> 0
<EXPENSES-NET> 2,549,640
<NET-INVESTMENT-INCOME> 12,698,298
<REALIZED-GAINS-CURRENT> 39,076
<APPREC-INCREASE-CURRENT> (15,675,222)
<NET-CHANGE-FROM-OPS> (2,937,848)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (12,698,298)
<DISTRIBUTIONS-OF-GAINS> (2,077,433)
<DISTRIBUTIONS-OTHER> (354,264)
<NUMBER-OF-SHARES-SOLD> 25,657,665
<NUMBER-OF-SHARES-REDEEMED> (40,612,658)
<SHARES-REINVESTED> 9,398,834
<NET-CHANGE-IN-ASSETS> (23,624,002)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 0
<OVERDISTRIB-NII-PRIOR> (256,091)
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 1,363,196
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 2,549,096
<AVERAGE-NET-ASSETS> 1,566,000
<PER-SHARE-NAV-BEGIN> 12.30
<PER-SHARE-NII> 0.51
<PER-SHARE-GAIN-APPREC> (0.69)
<PER-SHARE-DIVIDEND> (0.51)
<PER-SHARE-DISTRIBUTIONS> (0.11)
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 11.50
<EXPENSE-RATIO> 1.39
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 004
<NAME> NEW YORK SERIES (CLASS Z)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 243211090
<INVESTMENTS-AT-VALUE> 252499443
<RECEIVABLES> 3605588
<ASSETS-OTHER> 6938
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 410098
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 1171555
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 245527977
<SHARES-COMMON-STOCK> 22139491
<SHARES-COMMON-PRIOR> 22785976
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> -354264
<ACCUMULATED-NET-GAINS> 0
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 9356603
<NET-ASSETS> -44925467
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 15247938
<OTHER-INCOME> 0
<EXPENSES-NET> 2549640
<NET-INVESTMENT-INCOME> 12698298
<REALIZED-GAINS-CURRENT> 39076
<APPREC-INCREASE-CURRENT> -15675222
<NET-CHANGE-FROM-OPS> -2937848
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> -12698298
<DISTRIBUTIONS-OF-GAINS> -2077433
<DISTRIBUTIONS-OTHER> -354264
<NUMBER-OF-SHARES-SOLD> 25657665
<NUMBER-OF-SHARES-REDEEMED> -40612658
<SHARES-REINVESTED> 9398834
<NET-CHANGE-IN-ASSETS> -23624002
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 0
<OVERDISTRIB-NII-PRIOR> -256091
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 1363196
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 2549096
<AVERAGE-NET-ASSETS> 496,000
<PER-SHARE-NAV-BEGIN> 12.31
<PER-SHARE-NII> 0.6
<PER-SHARE-GAIN-APPREC> -0.6
<PER-SHARE-DIVIDEND> -0.69
<PER-SHARE-DISTRIBUTIONS> -0.11
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 11.51
<EXPENSE-RATIO> 0.63
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 001
<NAME> OHIO SERIES (CLASS A)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 71,137,763
<INVESTMENTS-AT-VALUE> 73,814,047
<RECEIVABLES> 1,090,743
<ASSETS-OTHER> 84,245
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 1,892,428
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 212,063
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 69,841,972
<SHARES-COMMON-STOCK> 6,430,138
<SHARES-COMMON-PRIOR> 6,859,774
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 300,725
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 2,741,847
<NET-ASSETS> (13,289,912)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 4,489,574
<OTHER-INCOME> 0
<EXPENSES-NET> 885,901
<NET-INVESTMENT-INCOME> 3,603,673
<REALIZED-GAINS-CURRENT> 769,806
<APPREC-INCREASE-CURRENT> (5,472,852)
<NET-CHANGE-FROM-OPS> (1,099,373)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (3,603,673)
<DISTRIBUTIONS-OF-GAINS> (1,791,144)
<DISTRIBUTIONS-OTHER> (62,001)
<NUMBER-OF-SHARES-SOLD> 6,020,350
<NUMBER-OF-SHARES-REDEEMED> (16,660,880)
<SHARES-REINVESTED> 3,287,977
<NET-CHANGE-IN-ASSETS> (13,908,744)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 394,089
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 407,892
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 883,851
<AVERAGE-NET-ASSETS> 50,833,000
<PER-SHARE-NAV-BEGIN> 12.31
<PER-SHARE-NII> 0.54
<PER-SHARE-GAIN-APPREC> (0.71)
<PER-SHARE-DIVIDEND> (0.54)
<PER-SHARE-DISTRIBUTIONS> (0.01)
<RETURNS-OF-CAPITAL> (0.26)
<PER-SHARE-NAV-END> 11.33
<EXPENSE-RATIO> 0.97
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 002
<NAME> OHIO SERIES (CLASS B)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 71,137,763
<INVESTMENTS-AT-VALUE> 73,814,047
<RECEIVABLES> 1,090,743
<ASSETS-OTHER> 84,245
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 1,892,428
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 212,063
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 69,841,972
<SHARES-COMMON-STOCK> 6,430,138
<SHARES-COMMON-PRIOR> 6,859,774
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 300,725
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 2,741,847
<NET-ASSETS> (13,289,912)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 4,489,574
<OTHER-INCOME> 0
<EXPENSES-NET> 885,901
<NET-INVESTMENT-INCOME> 3,603,673
<REALIZED-GAINS-CURRENT> 769,806
<APPREC-INCREASE-CURRENT> (5,472,852)
<NET-CHANGE-FROM-OPS> (1,099,373)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (3,603,673)
<DISTRIBUTIONS-OF-GAINS> (1,791,144)
<DISTRIBUTIONS-OTHER> (62,001)
<NUMBER-OF-SHARES-SOLD> 6,020,350
<NUMBER-OF-SHARES-REDEEMED> (16,660,880)
<SHARES-REINVESTED> 3,287,977
<NET-CHANGE-IN-ASSETS> (13,908,744)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 394,089
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 407,892
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 883,851
<AVERAGE-NET-ASSETS> 30,456,000
<PER-SHARE-NAV-BEGIN> 12.32
<PER-SHARE-NII> 0.51
<PER-SHARE-GAIN-APPREC> (0.71)
<PER-SHARE-DIVIDEND> (0.51)
<PER-SHARE-DISTRIBUTIONS> (0.01)
<RETURNS-OF-CAPITAL> (0.26)
<PER-SHARE-NAV-END> 11.34
<EXPENSE-RATIO> 1.27
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 003
<NAME> OHIO SERIES (CLASS C)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 71,137,763
<INVESTMENTS-AT-VALUE> 73,814,047
<RECEIVABLES> 1,090,743
<ASSETS-OTHER> 84,245
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 1,892,428
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 212,063
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 69,841,972
<SHARES-COMMON-STOCK> 6,430,138
<SHARES-COMMON-PRIOR> 6,859,774
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 300,725
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 2,741,847
<NET-ASSETS> (13,289,912)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 4,489,574
<OTHER-INCOME> 0
<EXPENSES-NET> 885,901
<NET-INVESTMENT-INCOME> 3,603,673
<REALIZED-GAINS-CURRENT> 769,806
<APPREC-INCREASE-CURRENT> (5,472,852)
<NET-CHANGE-FROM-OPS> (1,099,373)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (3,603,673)
<DISTRIBUTIONS-OF-GAINS> (1,791,144)
<DISTRIBUTIONS-OTHER> (62,001)
<NUMBER-OF-SHARES-SOLD> 6,020,350
<NUMBER-OF-SHARES-REDEEMED> (16,660,880)
<SHARES-REINVESTED> 3,287,977
<NET-CHANGE-IN-ASSETS> (13,908,744)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 394,089
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 407,892
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 883,851
<AVERAGE-NET-ASSETS> 289,000
<PER-SHARE-NAV-BEGIN> 12.32
<PER-SHARE-NII> 0.48
<PER-SHARE-GAIN-APPREC> (0.71)
<PER-SHARE-DIVIDEND> (0.48)
<PER-SHARE-DISTRIBUTIONS> (0.01)
<RETURNS-OF-CAPITAL> (0.26)
<PER-SHARE-NAV-END> 11.34
<EXPENSE-RATIO> 0.77
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 001
<NAME> PENNSYLVANIA SERIES (CLASS A)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 185,608,974
<INVESTMENTS-AT-VALUE> 190,302,790
<RECEIVABLES> 3,792,175
<ASSETS-OTHER> 115,115
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 171,276
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 427,994
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 188,379,259
<SHARES-COMMON-STOCK> 19,106,309
<SHARES-COMMON-PRIOR> 21,014,326
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 537,735
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 4,693,816
<NET-ASSETS> (40,120,635)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 12,282,159
<OTHER-INCOME> 0
<EXPENSES-NET> 2,083,494
<NET-INVESTMENT-INCOME> 10,198,665
<REALIZED-GAINS-CURRENT> 2,064,650
<APPREC-INCREASE-CURRENT> (15,124,349)
<NET-CHANGE-FROM-OPS> (2,861,034)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (10,198,665)
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> (2,400,686)
<NUMBER-OF-SHARES-SOLD> 26,494,078
<NUMBER-OF-SHARES-REDEEMED> (41,134,998)
<SHARES-REINVESTED> 7,127,006
<NET-CHANGE-IN-ASSETS> (22,974,299)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 0
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 1,051,974
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 2,078,172
<AVERAGE-NET-ASSETS> 104,460,000
<PER-SHARE-NAV-BEGIN> 10.92
<PER-SHARE-NII> 0.53
<PER-SHARE-GAIN-APPREC> (0.67)
<PER-SHARE-DIVIDEND> (0.53)
<PER-SHARE-DISTRIBUTIONS> (0.12)
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 10.13
<EXPENSE-RATIO> 0.84
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 002
<NAME> PENNSYLVANIA SERIES (CLASS B)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 185,608,974
<INVESTMENTS-AT-VALUE> 190,302,790
<RECEIVABLES> 3,792,175
<ASSETS-OTHER> 115,115
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 171,276
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 427,994
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 188,379,259
<SHARES-COMMON-STOCK> 19,106,309
<SHARES-COMMON-PRIOR> 21,014,326
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 537,735
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 4,693,816
<NET-ASSETS> (40,120,635)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 12,282,159
<OTHER-INCOME> 0
<EXPENSES-NET> 2,083,494
<NET-INVESTMENT-INCOME> 10,198,665
<REALIZED-GAINS-CURRENT> 2,064,650
<APPREC-INCREASE-CURRENT> (15,124,349)
<NET-CHANGE-FROM-OPS> (2,861,034)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (10,198,665)
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> (2,400,686)
<NUMBER-OF-SHARES-SOLD> 26,494,078
<NUMBER-OF-SHARES-REDEEMED> (41,134,998)
<SHARES-REINVESTED> 7,127,006
<NET-CHANGE-IN-ASSETS> (22,974,299)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 0
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 1,051,974
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 2,078,172
<AVERAGE-NET-ASSETS> 104,860,000
<PER-SHARE-NAV-BEGIN> 10.92
<PER-SHARE-NII> 0.50
<PER-SHARE-GAIN-APPREC> (0.67)
<PER-SHARE-DIVIDEND> (0.50)
<PER-SHARE-DISTRIBUTIONS> (0.12)
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 10.13
<EXPENSE-RATIO> 1.14
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 003
<NAME> PENNSYLVANIA SERIES (CLASS C)
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-1999
<PERIOD-END> AUG-31-1999
<INVESTMENTS-AT-COST> 185,608,974
<INVESTMENTS-AT-VALUE> 190,302,790
<RECEIVABLES> 3,792,175
<ASSETS-OTHER> 115,115
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 171,276
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 427,994
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 188,379,259
<SHARES-COMMON-STOCK> 19,106,309
<SHARES-COMMON-PRIOR> 21,014,326
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 537,735
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 4,693,816
<NET-ASSETS> (40,120,635)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 12,282,159
<OTHER-INCOME> 0
<EXPENSES-NET> 2,083,494
<NET-INVESTMENT-INCOME> 10,198,665
<REALIZED-GAINS-CURRENT> 2,064,650
<APPREC-INCREASE-CURRENT> (15,124,349)
<NET-CHANGE-FROM-OPS> (2,861,034)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (10,198,665)
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> (2,400,686)
<NUMBER-OF-SHARES-SOLD> 26,494,078
<NUMBER-OF-SHARES-REDEEMED> (41,134,998)
<SHARES-REINVESTED> 7,127,006
<NET-CHANGE-IN-ASSETS> (22,974,299)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 0
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 1,051,974
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 2,078,172
<AVERAGE-NET-ASSETS> 1,075,000
<PER-SHARE-NAV-BEGIN> 10.92
<PER-SHARE-NII> 0.47
<PER-SHARE-GAIN-APPREC> (0.67)
<PER-SHARE-DIVIDEND> (0.47)
<PER-SHARE-DISTRIBUTIONS> (0.12)
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 10.13
<EXPENSE-RATIO> 1.39
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
