SYNTHETECH INC
10KSB, 1996-06-05
INDUSTRIAL ORGANIC CHEMICALS
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<PAGE>
                                      
                  U. S. SECURITIES AND EXCHANGE COMMISSION
                                      
                           Washington, D.C. 20549
                                      
                                 FORM 10-KSB
                                      
                                 (Mark One)
[X]  ANNUAL REPORT PURSUANT TO SECTION 13 or 15(d) OF THE SECURITIES EXCHANGE
     ACT OF 1934 [Fee Required]
     For the fiscal year ended March 31, 1996
[  ] TRANSITION REPORT PURSUANT TO SECTION 13 or 15(d) OF THE SECURITIES
     EXCHANGE ACT OF 1934 [No Fee Required]
     For the transition period from __________ to __________
Commission file number 0-12992
                              SYNTHETECH, INC.
               (Name of small business issuer in its charter)
                                                    84-0845771
          Oregon
     (State or other jurisdiction        (I.R.S. Employer Identification
                                                       No.)
      of incorporation or organization)                  
                                                         
     1290   Industrial   Way,   Albany,               97321
     Oregon
     (Address  of  principal  executive             (Zip Code)
     offices)
                                                         
     Issuer's telephone number:                    541/967-6575
                                                         
     Securities registered pursuant  to                None
     Section 12(b) of the Act:
                                                              
     Securities   registered   pursuant   to                  
     Section 12(g) of the Exchange Act:
                                      
                        Common Stock, $.001 Par Value
                              (Title of class)
Check  whether issuer (1) filed all reports required to be filed by Section  13
or  15(d) of the Securities Exchange Act of 1934 during the past 12 months  (or
for such shorter period that the registrant was required to file such reports),
and  (2)  has  been subject to such filing requirements for the past  90  days.
YES  X   NO

Check if there is no disclosure of delinquent filers in response to Item 405 of
Regulation S-B contained in this form, and no disclosure will be contained,  to
the  best  of  registrant's  knowledge,  in  definitive  proxy  or  information
statements  incorporated by reference in Part III of this Form  10-KSB  or  any
amendment to this Form 10-KSB.  [ X ]

Issuer's revenues for its most recent fiscal year:  $8,472,000

As  of  May  30, 1996, the aggregate market value of the voting stock  held  by
nonaffiliates of the registrant was $68,776,654 based upon $8.50 per share (the
average of the closing bid and asked prices reported for such date on Nasdaq).
The number of the shares of the Company's Common Stock outstanding on May 30,
1996 was 13,510,736.
                                      
Transitional Small Business Disclosure Format (check one):  YES      NO  X
<PAGE>
                                      
                                   PART I
                                      
                              ITEM 1.  BUSINESS

Synthetech,  Inc.,  an  Oregon corporation (the "Company"  or  "Synthetech"),
produces Peptide Building Blocks and other fine chemicals using a combination
of organic chemistry and biocatalysis.

PRODUCT OVERVIEW

Peptide Building Blocks.  Peptides are short chains of generally less than 50
amino  acids  and are used primarily in pharmaceuticals.  The  production  of
peptides  requires amino acids which have been chemically modified to  enable
them  to more easily link with other amino acids in a particular sequence  to
form  the  desired peptide.  The Company refers to these chemically  modified
amino  acids  as "Peptide Building Blocks" or "PBBs."  The amino acids  which
are  transformed into PBBs may be either natural amino acids (that is,  amino
acids  which occur in nature) or synthetic amino acids (that is, amino  acids
which have a side chain that does not occur in nature).

Synthetech  chemically modifies natural amino acids (which it purchases  from
multiple suppliers) to produce PBBs.  The Company also manufactures synthetic
amino  acids, and chemically modifies these synthetic amino acids to  produce
PBBs.

The  Company has developed and scaled up process technology to produce a wide
range of PBB products at the multi-kilogram to multi-ton scale.

The Company currently offers over 300 different PBB products.  For the fiscal
years  ended  March  31, 1996, 1995, and 1994, the Company's  sales  of  PBBs
represented   99%  ($8,412,000),  89%  ($4,759,000)  and  82%   ($3,292,000),
respectively,  of the Company's total revenues.  For the fiscal  years  ended
March  31,  1996,  1995 and 1994, sales to overseas customers  accounted  for
approximately  21%,  19%  and  16%,  respectively,  of  the  Company's  total
revenues.  These sales were principally to Europe and Japan.

Other  Fine  Chemicals.   The  Company  also  produces  other  fine  chemical
compounds.   These  compounds  include  grignard  reagents  and  other   fine
chemicals  conforming  to the customer's confidential specifications.   These
chemicals  are  generally used by customers for their  own  internal  product
development.   However, with the growth in PBB sales, the Company  no  longer
actively markets grignard and other fine chemical products.  These sales have
declined to a nominal level in fiscal 1996.  For the fiscal years ended March
31,  1996,  1995  and  1994,  the Company's sales  of  other  fine  chemicals
represented 1% ($60,000), 10% ($513,000) and 18% ($742,000), respectively, of
the Company's total revenues.
                                      
                            _____________________

The  Company  continues to produce most bulk orders on an  as-ordered  basis,
although  it does carry an inventory of over 250 PBB products.   At  May  31,
1996,  the dollar amount of backlog orders which the Company believed  to  be
firm  was approximately $5.5 million (May 31, 1995 backlog was $2.6 million).
The May 31, 1996 backlog includes a single order for $2 million, portions  of
which are subject to certain cancellation provisions.  The Company expects to
fill all backlog orders within the current fiscal year.

In  January  1990, the Company entered into supply and technology  agreements
with  Biomeasure  Incorporated, a Boston area  biotechnology  company  and  a
subsidiary  of  Groupe Pharmaceutique Beaufour-Ipsen of France  with  several
synthetic  peptide  products under development.  Under the supply  agreement,
the  Company  has  agreed to supply all of Biomeasure's  requirements  for  a
particular synthetic PBB.  This agreement continues from year to year  unless
                                   2
<PAGE>
terminated in writing by one of the parties.  The Company and Biomeasure  are
also parties to a license agreement giving Biomeasure the option to receive a
license to produce for its own use the PBB which is the subject of the supply
agreement between the parties and Biomeasure must pay certain royalty amounts
based on the amount so produced.

MARKET OVERVIEW

The  market  for  peptide building blocks is driven by  the  market  for  the
peptides  in  which  they are incorporated.  The size of  this  market  is  a
function  of the number of peptides which are initially screened for  use  in
pharmaceuticals, the number of these pharmaceuticals which progress down  the
path  toward registration and, ultimately, the number which are found  to  be
therapeutically  useful.  The size of the market is also a  function  of  the
quantities  and  varieties of peptide building blocks  necessary  to  produce
these  pharmaceuticals.  Based on an analysis of fiscal 1996  PBB  sales  and
information  to  the extent available from customers, the  Company  estimates
that  approximately  12% of the Company's PBB sales  went  into  marketed  or
"approved" drugs, approximately 80% went into drugs in clinical or late  pre-
clinical  trials and approximately 8% went into drugs at the R&D or discovery
stage of development.

MARKETING

The  Company markets its products through attendance at trade shows, listings
in   biotechnology  and  chemical  industry  directories,  advertisements  in
chemical  trade  periodicals  and  by  contacting  pharmaceutical  and  other
companies which it believes might have a need for its products.  The  Company
also uses one independent sales representative on the East Coast.

CUSTOMERS

Although the Company has over 200 customers, the Company expects that  a  few
customers will continue to account for a significant portion of revenues each
year.  During fiscal 1996, the Company had four customers which accounted for
51%  of  the Company's revenues and two of those customers accounted for  23%
and 11%, respectively, of the Company's revenues.

COMPETITION

Because peptide-based pharmaceuticals are relatively new, the market  in  the
past  for peptide building blocks has been quite small -- with most sales  in
the  multi-kilo  or  smaller size.  As a result, the peptide  building  block
market has not attracted a significant amount of direct competition.  As  the
market  continues to grow with multi-ton order sizes becoming more prevalent,
the Company has begun to see more competition.

Current competition in multi-kilo or smaller quantities of natural amino acid
based  peptide  building blocks comes primarily from  several  European  fine
chemical companies. Multi-ton order sizes of these natural PBBs have begun to
attract  a wider group of domestic and international chemical companies.   In
the area of synthetic amino acid based  peptide  building  blocks, the  
Company  has  competition  on  a selective  product  basis from fine chemical
producers in Europe  and  Japan.  Competition  also increases for supplying 
PBBs for drug development  programs that reach late clinical trials and move 
into approved status as a result  of the   increased   quantities  typically 
required   at   these   stages   and pharmaceutical  company  requirements 
to  have  second  sources  of  material available.  The Company's competitors
have technical, financial, selling  and other  resources available to them 
which are significantly greater than those available to the Company.

The  principal  methods  of competition in the market  for  peptide  building
blocks and other fine chemicals are quality, customer service and price.  The
Company  believes that it competes effectively in each of these  areas.   The
Company  also believes that its production of a wide range of products  gives
it  a  competitive  advantage in the marketplace.  In addition,  the  Company
                                     3
<PAGE>
believes  that  most  pharmaceutical companies view  internal  production  of
peptide building blocks as a misallocation of resources and, given a reliable
source  of  a  quality  product, would rather obtain  them  from  an  outside
supplier.

RESEARCH AND DEVELOPMENT

The  Company's  research and development efforts have focused principally  on
process  technology improvements.  During the fiscal years  ended  March  31,
1996,  1995  and 1994, the Company's research and development  expenses  were
$217,000, $169,000 and $144,000, respectively.

EMPLOYEES

As  of  May 31, 1996, the Company employed thirty-three individuals,  two  of
whom were part-time.

REGULATORY MATTERS

As  the  Company's  products are intermediates sold to final  producers,  the
Company has been generally unaffected by FDA regulation which is directed  at
final  products  sold  to the public.  The Company's customers  do,  however,
typically  impose inspection and quality assurance programs on  the  Company.
These   programs   involve  materials  handling,  recordkeeping   and   other
requirements. As some customers  have begun to request the Company to provide
additional  processing  steps, these programs often  include  more  extensive
requirements.   The Company anticipates that the expenses of  complying  with
such programs will increase in the future.

The Company's business is also subject to substantial regulation in the areas
of safety, environmental release and hazardous waste disposal.  As additional
and more extensive regulations are being added in these areas at the federal,
state  and  local  levels, the compliance costs will inevitably  continue  to
increase.   The  operation  of  chemical  manufacturing  plants  entails  the
inherent  risk of environmental damage or personal injury due to the handling
of  potentially  harmful  substances, and there  can  be  no  assurance  that
material costs and liabilities will not be incurred in the future because  of
an  accident  or other event resulting in personal injury or an  unauthorized
release  of such substances to the environment.  Also, the Company  generates
hazardous  and  other  wastes  which are  disposed  of  at  various  off-site
facilities.  The Company may be liable, irrespective of fault,  for  material
cleanup costs or other liabilities incurred at these disposal facilities  due
to releases of such substances into the environment.

The Company maintains property damage and liability insurance.  In connection
with  an overall review of its risk management program, the Company has  also
obtained  environmental  risk insurance but does not have  product  liability
insurance.

COMPANY BACKGROUND

The  Company was formed in 1981 to develop novel chemical process  technology
by combining classical organic chemistry with enzyme-based biocatalysis.  For
the  first  several years, it operated mainly as a research  and  development
group  focused on the production of pharmaceuticals and other fine chemicals.
After  its  initial public offering in 1984, the Company's  research  efforts
were  concentrated on the development of a proprietary process for  aspartame
and  L-phenylalanine.  Although the Company had entered into one license  for
this technology, the Company does not expect additional licensing revenue.

Throughout  its  development  during the  1980s,  the  Company  also  offered
contract  research services.  These research services were typically provided
to   pharmaceutical  clients  and  generally  involved  the  development   of
biocatalytic processes (that is, chemical processes which are affected by the
use of enzymes or microorganisms).  Since the end of fiscal 1990, the Company
has  phased out contract research services and does not anticipate  receiving
                                  4
<PAGE>
any significant revenue from research services in the future.  By the end  of
the  1980s, the Company, building on it prior experience, began to  focus  on
the production of PBBs and other fine chemicals.
                                      
                             ITEM 2.  PROPERTIES

Synthetech's  headquarters  and production facility  is  located  in  Albany,
Oregon.   The  Company purchased this facility in 1987.   This  approximately
23,000  square  foot  facility includes production, pilot plant,  laboratory,
warehouse and office space.

The  Company also is constructing an additional 20,000 square foot, two-story
production  facility  at its Albany, Oregon location.   The  new  plant  will
substantially  increase  the Company's capacity to  produce  PBBs  and  other
pharmaceutical  intermediaries.  This facility will have six bays,  of  which
two  will be outfitted immediately with manufacturing equipment and four will
be  available for future expansion.  The Company estimates that the  cost  of
the  building shell plus the equipment to be used in the first two bays  will
be approximately $6 million and will be completed in the Spring of 1997.

Although  the  Company  expects  to  finance  the  majority  of  its  capital
improvements from working capital, it is also exploring the possible  use  of
bank debt and other outside funding sources for a portion of the cost.
                                      
                         ITEM 3.  LEGAL PROCEEDINGS

Not applicable.


                                      
        ITEM 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

Not applicable.
                                     5
<PAGE>                                      
                                   PART II
                                      
      ITEM 5.  MARKET FOR COMMON EQUITY AND RELATED SHAREHOLDER MATTERS

The  Company's Common Stock is traded over-the-counter and is listed  in  the
National  Association  of  Securities  Dealers  Automated  Quotation   System
(Nasdaq) under the symbol "NZYM." The following table sets forth the range of
high  and  low  bid quotations for the Common Stock for the two  most  recent
fiscal  years, as reported by Nasdaq.  These quotations reflect  inter-dealer
prices, without retail markup, markdown or commission and may not necessarily
represent  actual  transactions.   In  May  1996,  the  Company  applied  for
inclusion of the Company's Common Stock in the Nasdaq National Market.
                                 
<TABLE>
<CAPTION>
<S>                 <C>        <C>          <C>         <C>
                                          
                            Fiscal Year Ended March 31,
                                                       
                           1996                     1995
                                                             
                     High         Low         High         Low
                                                         
First Quarter       $3.06       $2.06        $2.63       $2.00
                                                         
Second Quarter       4.75        3.03         2.56        2.00
                                                         
Third Quarter        5.25        3.81         2.16        1.69
                                                         
Fourth Quarter       5.88        4.06         2.19        1.69
</TABLE>
The number of record holders of Common Stock as of May 21, 1996 was
approximately 765.
     
No dividends on the Company's Common Stock have been paid since inception and
the Company does not anticipate that dividends will be paid in the
foreseeable future.
                                   6
<PAGE>
                                      
     ITEM 6.  MANAGEMENT'S DISCUSSION AND ANALYSIS OR PLAN OF OPERATIONS

RESULTS OF OPERATIONS

The following table sets forth, for the periods indicated, the percentage  of
revenues represented by each item included in the Statements of Income.
<TABLE>
<CAPTION>
<S>                          <C>     <C>      <C>
                               Percentage of Revenues
                             Fiscal Year Ended March 31,
                                                  
                               1996    1995     1994
                                               
Revenues                      100.0%  100.0%   100.0%
Cost of Sales                  43.5    48.5     48.5
Gross Profit                   56.5    51.5     51.5
                                               
Research and Development        2.6     3.2      3.6
Selling, General and            9.8    14.4     16.6
Administrative
Operating Income               44.1    33.9     31.3
                                               
Other Income                    3.4     1.3      1.6
Interest Expense                  -     0.5      0.9
Income Before Income Taxes     47.5    34.7     32.0
Provision for Income Taxes     17.1     8.3      3.2
Net Income                     30.4    26.4     28.8

</TABLE>
Revenues

Synthetech  revenues were $8.47 million, $5.36 million and $4.03  million  in
fiscal  1996, 1995 and 1994, respectively.  This reflects a 58%  increase  in
revenues from fiscal 1995 to fiscal 1996 and a 33% increase in revenues  from
fiscal 1994 to fiscal 1995.  The growth in revenues during the past two years
has  been attributable to increased product sales reflecting continued market
development  of the product lines of Peptide Building Blocks  (PBBs).   As  a
result  of new products and increased volume of existing products,  sales  of
PBBs,  the Company's primary product line, were $8.41 million in fiscal 1996,
up  77% over fiscal 1995 and $4.76 million in fiscal 1995, up 45% over fiscal
1994 revenues of $3.29 million.

In  fiscal  1996, based on an analysis of the Company's sales and information
to   the  extent  available  from  customers,  the  Company  estimates   that
approximately 12% of the Company's PBB sales went into marketed or "approved"
drugs,  approximately  80% went into drugs in clinical or  late  pre-clinical
trials  and  approximately 8% went into drugs at the R&D or discovery  stage.
In both fiscal 1995 and fiscal 1994, the Company estimates that approximately
one-sixth of the Company's PBB sales went into marketed or "approved" drugs,
approximately two-thirds went into drugs in clinical or late pre-clinical
trials, and approximately one-sixth went into drugs at the R&D discovery
stage.  Accordingly, revenues in fiscal 1996, as compared to the prior two
years, increased substantially in the clinical or late pre-clinical trial
phases, increased moderately for approved drugs, and were relatively stable
for R&D.

Revenues  for  fiscal 1996 included sales associated with one  PBB  order  of
$1.97  million  being used in late stage clinical trials by a  pharmaceutical
company  compared to revenues of $47,000 for that PBB in fiscal 1995.   Sales
of  this  magnitude relative to the Company's aggregate revenues  demonstrate
the  continuing potential for fluctuations in revenues from period to period.
The  Company  has  not yet established a stable baseload of  demand  for  its
products.  The Company's products are part of a new and emerging market  with
sizable fluctuations in orders between periods.  In most instances, order  or
                                    7
<PAGE>
reorder  cycles  for  products  are  not predictable.   Demand  for  PBBs  is
extremely  variable  since  individual clinical  trial  programs  are  always
subject  to significant risk of suspension or early cancellation and  only  a
small  percentage of drugs in clinical trial programs are ultimately approved
for  market  use.   As  a  result, the Company expects  to  continue  to  see
fluctuations in its revenues from period to period.  See "Industry Factors."

Sales  of  grignard reagents and other fine chemicals were $60,000 in  fiscal
1996  compared to $513,000 in fiscal 1995 and $742,000 in fiscal 1994.   With
the  growth of PBB sales, the Company no longer actively markets grignard and
other fine chemical products.

Gross Profit

Gross  profit  was $4.79 million, $2.76 million and $2.08 million  in  fiscal
1996,  1995  and 1994, respectively.  This reflects a 74% increase  in  gross
profit  from  fiscal 1995 to fiscal 1996 and a 33% increase in  gross  profit
from  fiscal 1994 to fiscal 1995.  As a percent of sales, gross profits  were
56.5%,  51.5%  and  51.5%  in  fiscal  1996,  1995  and  1994,  respectively.
Increased revenues positively affect gross profit margins since a portion  of
the Company's manufacturing overhead costs are relatively fixed.  The mix  of
products  sold during any period can also significantly affect  gross  profit
margins  either positively or negatively.  The increase in the  gross  profit
margins for fiscal 1996 over fiscal 1995 resulted from the increased level of
revenues  combined  with the mix of products.  Although in  fiscal  1995  and
fiscal  1994, gross profit as a percentage of sales was flat, the quarter  to
quarter  percentages  ranged  from 44% to 60%,  illustrating  the  impact  of
revenues  and  product  mix.  Similarly, the quarter to  quarter  percentages
during fiscal 1996 ranged from 49% to 66%.  The Company expects revenues  and
product  mix  to  continue  to  fluctuate from period  to  period  and  cause
variation in gross profit margins.

Operating Expenses

Research  and development ("R&D") expense increased to $217,000  or  2.6%  of
sales  in  1996  from  $169,000 or 3.2% of sales in 1995.   R&D  expense  was
$144,000  or  3.6% in fiscal 1994.  The increase in R&D expense since  fiscal
1994  primarily  reflects the October 1994 hiring of an additional  technical
employee in the R&D area.

Selling,  general and administrative ("SG&A") expense was $833,000,  $774,000
and  $671,000 in fiscal 1996, 1995 and 1994, respectively.  SG&A  expense  in
fiscal  1996 and fiscal 1995 were relatively stable with the modest  increase
in  fiscal  1996  resulting  from a one-time property  assessment  which  the
Company  expensed and slight increases in other expenses resulting  from  the
significant  increase in sales.  The increase in SG&A  in  fiscal  1995  from
fiscal  1994  principally reflected base salary and bonus  increases.   As  a
percentage of sales, SG&A, however, has consistently decreased.  SG&A as a 
percentage of sales was 9.8%,14.4% and 16.6% for fiscal 1996, 1995 and 1994, 
respectively.

Operating Income

Operating  income was $3.74 million in fiscal 1996, $1.82 million  in  fiscal
1995  and $1.26 million in fiscal 1994.  In fiscal 1996 labor costs increased
21%,  roughly half of such increase was attributable to salary increases and  
the remainder resulted from an increase in employee hiring beginning in the 
second half of fiscal  1995.   As  a percentage of revenues, operating income
increased  to 44.1%  in  fiscal 1996 compared to 33.9% in fiscal 1995 and 
31.3%  in  fiscal 1994.   The increase in operating margin reflected the 
ability of the Company to   significantly   increase  its  revenues  and  
product   volume   without corresponding increases in operating costs.

Other Income

The $285,000 net other income in fiscal 1996 primarily resulted from $242,000
of interest earnings and $43,000 of recognized gain on the sale of securities
available  for  sale.  The $70,000 net other income in fiscal 1995  primarily
included $162,000 of interest earnings, reduced by $38,000 in realized losses
                                    8
<PAGE>
from  the sale of marketable trading securities, and a $56,000 write down  of
the  Company's  holdings of marketable trading securities.  In January  1995,
the  Company  discontinued  its active trading policy  with  respect  to  its
marketable  securities  (see Note B to the Financial Statements  for  a  more
detailed discussion).

Interest  expense was $0 in fiscal 1996, $27,000 in fiscal 1995, and  $35,000
in  fiscal  1994.  Interest expense was principally attributable to  interest
payments on the Company's SBA loan which was repaid in full in February 1995.
Since February 1995, the Company has not incurred any long-term debt.

Net Income

In  fiscal  1996,  the Company earned $4.02 million before income  taxes.   A
provision  for  income  taxes of $1.45 million  resulted  in  net  income  of
$2.57 million.  The provision for income taxes in fiscal 1996 included a one-
time  credit  of  $132,000 from the State of Oregon.   In  fiscal  1995,  the
Company  earned  $1.86 million before income taxes.  A provision  for  income
taxes of $444,000 resulted in net income of $1.42 million.  The provision for
income  taxes  for fiscal 1995 included utilization of all remaining  federal
net operating loss carryforwards.

In  fiscal  1994,  the Company earned $1.29 million before income  taxes.   A
provision   for  income  taxes  of  $129,000  resulted  in  net   income   of
$1.16  million.   The  provision for income taxes for  fiscal  1994  included
utilization  of $440,000 in tax benefits derived from federal  net  operating
loss carryforwards.

INDUSTRY FACTORS

The  market for PBBs is driven by the market for the peptide-based  drugs  in
which  they  are  incorporated.  Since there are only a handful  of  approved
peptide-based drugs on the market today, this market is still very  early  in
development  and  a substantial amount of the activity is  occurring  at  the
earlier stages of research and development and clinical trials.  Developments
of   new   biological  information,  based  on  rational  drug   design   and
combinatorial   chemistry,   are  creating  additional   peptide-based   drug
candidates.   Cost  pressures in the pharmaceutical industry,  however,  have
tightened  the criteria used to assess drug prospects at all phases  of  drug
development programs.  Cost pressures in the pharmaceutical industry can also
cause pharmaceutical companies to investigate alternative drug manufacturing 
processes which may not include the Company's products as an intermediate.

As a supplier of building blocks for peptide-based drugs, Synthetech's
revenues will be affected by these industry factors.  The high cancellation
rate for drug development programs results in a significant likelihood that
there will be no subsequent or "follow-on" PBB sales for any particular drug
development program.  Since Synthetech's revenue comes predominantly from
PBBs used in drug development programs, the overall impact on Synthetech's
business from the cancellation rate will depend, to a large extent, on the
rate of new drug development efforts being commenced.

The  advancement of a drug for which Synthetech is providing PBBs from a drug
development  program  into  an  "approved"  status  by  the  FDA  could  also
significantly affect Synthetech's business if Synthetech is able to  continue
to supply the PBB for the approved drug.  With the increased volume typically
associated  with  "approved" drugs, the Company,  however,  expects  to  face
increased competition for this business.

These  industry  factors  combined with timing  of  customer  and  regulatory
decisions and other unanticipated events may produce substantial fluctuations
in Synthetech's revenues for the foreseeable future.

LIQUIDITY AND CAPITAL RESOURCES

At March 31, 1996, the Company had working capital of $8.16 million compared
to  $3.57 million at March 31, 1995 and $4.12 million at March 31, 1994.  The
increase in working capital reflects the higher level of revenues in 1996 and
the  exercise  by  a  warrant holder of a warrant to purchase  common  stock,
                                  9
<PAGE>
pursuant  to which the Company received $993,000.  The Company's  cash,  cash
equivalents  and short-term securities available for sale at March  31,  1996
totaled  $5.44 million.  In addition, the Company has a $1,000,000 bank  line
of  credit.   This line of credit is secured by the Company's chattel  paper,
accounts,  contract rights and general intangibles.  As  of  March  31,  1996
there was no amount outstanding under the bank line.

The  increase in accounts receivable to $1.36 million at March 31, 1996  from
$840,000 at March 31, 1995 and $512,000 at March 31, 1994 reflects the higher
level  of  revenues  in  fiscal  1996 compared  to  prior  years.   Inventory
increased to $1.92 million at March 31, 1996 from $1.58 million at March  31,
1995 and $1.5 million at March 31, 1994.  These increases also reflected  the
increased level of revenues.

In   September  1995,  in  response  to  approaching  manufacturing  capacity
constraints  in  its  existing  facility,  the  Company  announced  plans  to
construct  a  new plant to increase its capacity to produce  PBBs  and  other
pharmaceutical intermediates.  The Company is currently in the  later  stages
of  plant  design and expects overall engineering, construction and equipment
costs  to be approximately $6 million.  The expected completion date for  the
new  plant  is spring of 1997.  The Company has also added a third production
shift at its present facility.  See Item 2, "Properties."

The  Company's capital expenditures were approximately $461,000 during fiscal
1996.   In  addition  to  the  new plant, the Company  currently  anticipates
acquiring approximately $500,000 of additional equipment and upgrades for the
existing  plant  and  equipment during fiscal 1997.  The Company  expects  to
finance a majority of these capital expenditures from internal cash flow, but
it is also exploring bank financing and other outside funding sources.

The Company owns its headquarters plant and all of its equipment.  See Note D
of  the  Notes  to  Financial Statements for a description of  the  Company's
property, plant and equipment.
                                 10
<PAGE>
                                      
                        ITEM 7.  FINANCIAL STATEMENTS


                                    Index
                                                                    Page
     
     Report of Independent Public Accountants for the years 
       ended March 31, 1996, 1995 and 1994....                       12
     
     Financial Statements:
     
       Balance Sheets as of March 31, 1996 and 1995..........        13-14
     
       Statements of Income for the years ended March 31,
         1996, 1995 and 1994.................................        15
     
       Statements of Shareholders' Equity for the years 
         ended March 31, 1996, 1995 and 1994.................        16
     
       Statements of Cash Flows for the years ended 
         March 31, 1996, 1995, and 1994......................        17
     
     Notes to Financial Statements:
     
       Note A - General and Business.........................        18
     
       Note B - Summary of Significant Accounting Policies...        18
     
       Note C - Inventories..................................        19
     
       Note D - Property, Plant and Equipment................        19
     
       Note E - Income Taxes.................................        20
     
       Note F - Line of Credit...............................        20
     
       Note G - Shareholders'Equity..........................        21-22
     
       Note H - 401(k) Profit Sharing Plan...................        22
     
       Note I - Segment Information..........................        22
     
                                11
<PAGE>
REPORT OF INDEPENDENT PUBLIC ACCOUNTANTS

To the Board of Directors and Shareholders of Synthetech, Inc.:

We  have  audited  the  accompanying balance sheets of Synthetech,  Inc.  (an
Oregon corporation) as of March 31, 1996 and 1995, and the related statements
of income, stockholders' equity and cash flows for each of the three years in
the  period  ended  March  31,  1996.  These  financial  statements  are  the
responsibility of the Company's management.  Our responsibility is to express
an opinion on these financial statements based on our audits.

We  conducted  our  audit  in  accordance with  generally  accepted  auditing
standards.   Those standards require that we plan and perform  the  audit  to
obtain  reasonable assurance about whether the financial statements are  free
of  material  misstatement.  An audit includes examining, on  a  test  basis,
evidence  supporting the amounts and disclosures in the financial statements.
An   audit  also  includes  assessing  the  accounting  principles  used  and
significant  estimates made by management, as well as evaluating the  overall
financial  statement  presentation.  We believe that  our  audits  provide  a
reasonable basis for our opinion.

In our opinion, the financial statements referred to above present fairly, in
all material respects, the financial position of Synthetech, Inc. as of March
31,  1996 and 1995, and the results of its operations and its cash flows  for
each of the three years in the period ended March 31, 1996 in conformity with
generally accepted accounting principles.


Portland, Oregon,
May 16, 1996
                                     12
<PAGE>
          
                              SYNTHETECH, INC.
                                      
                               BALANCE SHEETS
                                      
                                      
<TABLE>
<CAPTION>
 <S>                                           <C>           <C>
                                              For the Years Ended March 31
                                                    1996           1995

         ASSETS

     CURRENT ASSETS:
       Cash and cash equivalents                $ 5,049,000    $ 1,199,000
       Securities available for sale                395,000        250,000
       Accounts receivable, less allowance for
        doubtful accounts of $15,000 and $13,000
         for 1996 and 1995                         1,355,000       840,000
       Inventories                                 1,924,000     1,581,000
       Prepaid expenses                               71,000        54,000
       Income tax receivable                         152,000             -
       Deferred income taxes                          59,000        39,000
       Other current assets                            1,000         7,000
          TOTAL CURRENT ASSETS                     9,006,000     3,970,000

     PROPERTY, PLANT AND EQUIPMENT, at cost,net    1,311,000     1,052,000

     SECURITIES AVAILABLE FOR SALE                   626,000     1,619,000

     OTHER ASSETS                                     16,000        20,000
          TOTAL ASSETS                           $10,959,000   $ 6,661,000
                                                 ===========   ===========
</TABLE>
                      See notes to financial statements.
                                         13
<PAGE>
                              SYNTHETECH, INC.
                                      
                               BALANCE SHEETS
                                      
                                 (continued)
<TABLE>
<CAPTION>
<S>                                             <C>           <C>
                                                For the Years Ended March 31
                                                     1996           1995

       LIABILITIES AND SHAREHOLDERS' EQUITY

     CURRENT LIABILITIES:
       Accounts payable                          $   271,000   $   179,000
       Accrued compensation                          479,000       160,000
       Income taxes payable                                -        47,000
       Other accrued liabilities                       1,000        10,000
       Deferred revenue                               98,000             -
       TOTAL CURRENT LIABILITIES                     849,000       396,000

     DEFERRED INCOME TAXES                            10,000         6,000

     SHAREHOLDERS' EQUITY:
       Common stock, $.001 par value; authorized
        100,000,000 shares; issued and outstanding,
        13,475,000 and 12,054,000 shares               13,000       12,000
       Paid-in capital                              6,589,000    5,196,000
       Employee notes receivable and deferred
        compensation                                 (130,000)           -
       Unrealized gain on securities available
       for sale                                        30,000       27,000
       Retained earnings                            3,598,000    1,024,000
     TOTAL SHAREHOLDERS' EQUITY                    10,100,000    6,259,000
TOTAL LIABILITIES AND SHAREHOLDERS' EQUITY       $10,959, 000  $ 6,661,000
                                                 ============  ===========
                     See notes to financial statements.
</TABLE>
                                         14
<PAGE>
                              SYNTHETECH, INC.
                                      
                            STATEMENTS OF INCOME
                                      
<TABLE>
<CAPTION>
<S>                                  <C>           <C>           <C>
     For the Years Ended March 31        1996          1995          1994

     REVENUES                         $8,472,000    $5,357,000    $4,034,000
       Cost of sales                   3,685,000     2,598,000     1,956,000

     GROSS PROFIT                      4,787,000     2,759,000     2,078,000

       Research and development          217,000       169,000       144,000
       Selling, general and
         administrative                  833,000       774,000       671,000

     OPERATING EXPENSES                1,050,000       943,000       815,000

     OPERATING INCOME                  3,737,000     1,816,000     1,263,000

     OTHER INCOME, net                   285,000        70,000        65,000
     INTEREST EXPENSE                          -        27,000        35,000

     INCOME BEFORE INCOME TAXES        4,022,000     1,859,000     1,293,000

     PROVISION FOR INCOME TAXES        1,448,000       444,000       129,000

     NET INCOME                       $2,574,000    $1,415,000    $1,164,000
                                      ==========    ==========    ==========

     NET INCOME PER COMMON SHARE           $0.19         $0.11         $0.09
                                           =====         =====         =====
     SHARES USED IN PER SHARE
          CALCULATION                 13,727,960    12,969,701    13,166,363
                                      ==========    ==========    ==========

                     See notes to financial statements.
</TABLE>
                                          15
<PAGE>
                              SYNTHETECH, INC.
                                      

                     STATEMENTS OF SHAREHOLDERS' EQUITY
                                      
     For the Years Ended March 31
<TABLE>
<CAPTION>
<S>                        <C><C>          <C>           <C>      <C><C>
     
                                                        EMPLOYEE NOTES   GAIN ON      RETAINED
                                COMMON STOCK              RECEIVABLE   SECURITIES     EARNINGS   
                                               PAID-IN    & DEFERRED    AVAILABLE  (ACCUMULATED
                                SHARES AMOUNT  CAPITAL    COMPENSATION   FOR SALE     (DEFICIT)
                                ------ ------  -------    ------------  ---------  ------------
BALANCE, March 31, 1993     11,955,000 $12,000 $5,098,000  $        --  $       --  ($1,555,000)
 Issuance of stock for the
  exercise of stock options     56,000      --     54,000           --          --           --               --
 Net income                         --      --         --           --          --    1,164,000
                            ---------- ------- ---------- ------------  ----------  -----------
BALANCE, March 31, 1994     12,011,000 $12,000 $5,152,000  $        --  $       --    ($391,000)
 Issuance of stock for the
  exercise of stock options     43,000      --     37,000           --          --           --
 Income tax benefit of
  disqualifying dispositions        --      --      7,000           --          --           --
 Unrealized gain on 
  marketable securities 
   available for sale               --      --         --           --      27,000           --                          --
 Net income                         --      --         --           --          --    1,415,000
                            ---------- ------- ---------- ------------ -----------    ---------
Balance, March 31, 1995     12,054,000 $12,000 $5,196,000 $         -- $     27,000   $1,024,000
 Issuance of stock for the
  exercise of stock options    421,000      --    255,000           --           --          --
 Issuance of stock for the
  exercise of stock warrant  1,000,000   1,000    992,000           --           --          --
 Issuance of stock options
  at below fair value               --      --     70,000      (70,000)          --          --
 Amortization of deferred
  compensation                      --      --         --       20,000           --          --
 Employee notes receivable          --      --         --      (80,000)          --          --
 Income tax benefit of
  disqualifying dispositions        --      --     76,000           --           --          --
 Unrealized gain on securities       
  available for sale                --      --         --           --        3,000          --
 Net income                         --      --         --           --           --   2,574,000
                             --------- ------- ---------- ------------ ------------  ---------- 
BALANCE, March 31, 1996     13,475,000 $13,000 $6,589,000    ($130,000)$     30,000  $3,598,000
                            ========== ======= ========== ============ ============  ==========                ========
                     See notes to financial statements.
</TABLE>
                                          16
<PAGE>
                              SYNTHETECH, INC.
                                      
                          STATEMENTS OF CASH FLOWS
<TABLE>
<Catpion>
<S>                                          <C>       <C>        <C>
                                               For the Years Ended March 31
                                                 1996      1995       1994
 CASH FLOWS FROM OPERATING ACTIVITIES 
  (NOTE B):
  Net income                                  $2,574,000 $1,415,000 $1,164,000
   Adjustments to reconcile net income to
    net cash provided by operating activities:
     Depreciation, amortization and other        205,000    165,000    104,000
     Amortization of deferred compensation        20,000          -          -
     Gain on sales of property, plant and 
      equipment                                        -    (18,000)   (17,000)
     Loss on marketable trading securities             -     95,000     56,000
     Purchases of marketable trading securities        -   (944,000)(4,844,000)
     Proceeds from sale of marketable trading 
      securities                                       -    906,000  3,756,000
     Accrued interest on securities available 
      for sale                                    13,000          -          -
     Realized gain on securities available 
      for sale                                   (43,000)         -          -
     Deferred taxes                              (16,000)   (22,000)   (11,000)
    (Increase) decrease in assets:
      Accounts receivable, net                  (515,000)  (328,000)   238,000
      Inventories                               (343,000)   (84,000)  (384,000)
      Prepaid expenses                           (17,000)     2,000    (15,000)
      Income tax receivable                     (152,000)         -          -
      Other assets                                 6,000     (6,000)    45,000
     Increase (decrease) in liabilities:
      Accounts payable and accrued expenses      355,000     (6,000)   (37,000)
      Deferred revenue                            98,000          -          -
     Net cash provided by operating 
       activities                              2,185,000  1,175,000     55,000
 CASH FLOWS FROM INVESTING ACTIVITIES:
  Property, plant and equipment purchases       (461,000)  (218,000)  (396,000)
  Proceeds from sales of property, plant
   and equipment                                       -     18,000     17,000
  Proceeds from sale/maturities of securities 
   available for sale                            882,000          -          -
  Employee notes receivable                      (80,000)         -          -
     Net cash provided by (used by) investing  
      activities                                 341,000   (200,000)  (379,000)
 CASH FLOWS FROM FINANCING ACTIVITIES:
  Principal payments under long-term debt 
   obligations                                         -   (399,000)   (29,000)
  Proceeds from stock option exercises and
   disqualifying dispositions                    331,000     44,000     53,000
  Proceeds from stock warrant exercise           993,000          -          -
     Net cash provided by (used in) financing 
      activities                               1,324,000   (355,000)    24,000
 NET INCREASE (DECREASE) IN CASH AND CASH 
  EQUIVALENTS                                  3,850,000    620,000   (300,000)

 CASH AND CASH EQUIVALENTS AT BEGINNING OF 
  YEAR                                         1,199,000    579,000    879,000

 CASH AND CASH EQUIVALENTS AT END OF YEAR     $5,049,000 $1,199,000 $  579,000
                                              ========== ========== ==========
 NON-CASH INVESTING ACTIVITIES:
  Unrealized gain on securities available 
   for sale                                   $    3,000    27,000           -
  Issuance of stock options at below fair 
   value                                      $   70,000         -           -
</TABLE>        
                     See notes to financial statements.
                                               17
<PAGE>
                              SYNTHETECH, INC.
                        NOTES TO FINANCIAL STATEMENTS
          
NOTE A.   GENERAL AND BUSINESS

          Synthetech,  Inc., an Oregon corporation, produces specialty  amino
          acids  and  other  fine  chemicals using a combination  of  organic
          chemistry and biocatalysis.  The Company's primary product emphasis
          is  on specialty amino acids referred to as Peptide Building Blocks
          which  are  sold  domestically  and  internationally  to  companies
          developing peptide-based pharmaceuticals.

NOTE B.   SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES
          
          Use  of  Estimates:   The  preparation of financial  statements  in
          conformity  with generally accepted accounting principles  requires
          management  to  make  estimates and  assumptions  that  affect  the
          reported  amounts  of  assets  and liabilities  and  disclosure  of
          contingent  assets  and liabilities at the date  of  the  financial
          statements and the reported amounts of revenues and expenses during
          the  reporting  period.   Actual results could  differ  from  those
          estimates.
          
          Cash  and  Cash  Equivalents:  Cash and  cash  equivalents  include
          demand cash and all investments purchased with an original maturity
          of three months or less.
          
          Securities  Available For Sale:  In 1993, the Financial  Accounting
          Standards Board issued Statement No. 115 (SFAS 115), Accounting for
          Certain  Investments  in  Debt  and  Equity  Securities.   Although
          adoption  of SFAS 115 is not required until fiscal years  beginning
          after  December 15, 1993, the Company elected earlier  adoption  in
          fiscal  1994.   The adoption of SFAS 115 did not  have  a  material
          impact   on   the  Company's  financial  position  or  results   of
          operations.  In January, 1995, the Company discontinued its  active
          trading  policy with respect to its marketable securities,  due  to
          current  market  conditions.   The Company  no  longer  intends  to
          actively trade these marketable securities.  The securities may  be
          held until maturity depending upon the Company's cash flow needs or
          until   changes  in  the  investment  markets  dictate   otherwise.
          Accordingly,  all investments as of March 31,  1996 and  1995  have
          been  reflected as securities available for sale and any unrealized
          gain  or  loss  reflected as a separate component of  shareholders'
          equity  in accordance with SFAS 115.  Prior to January 1, 1995  and
          since  adoption  of  SFAS 115, the Company had  accounted  for  its
          investments as trading securities with unrealized gains and  losses
          recorded in the statement of income.
          
          Securities   available  for  sale  consist  mostly  of   government
          obligations  which mature during 1997, 1998 and 1999.  The  Company
          determines  cost  basis  in  its  investments  using  the  specific
          identification method.
          
          Property,  Plant and Equipment:  Property, plant and equipment  are
          recorded  at  cost.  Depreciation and amortization are provided  on
          the  straight-line method over seven to forty years  for  buildings
          and  land  improvements,  and five to  seven  years  on  all  other
          property.   When  property  is  sold  or  retired,  the  cost   and
          accumulated depreciation reserves are removed from the accounts and
          the resulting gain or loss is included in income.
          
          Revenue  Recognition:   Sales  of  products  are  recognized   when
          products are shipped.
          
          Research and Development Costs:  Research and development costs are
          expensed as incurred.
          
          Other Assets:  Other assets primarily represent patent costs, which
          are amortized over the useful life of the patent.
          
          Earnings  Per  Share:  Earnings per share are  computed  using  the
          weighted  average  number  of shares and common  stock  equivalents
          (stock  options and warrants) outstanding during the  period.   The
          shares  used in the basic earnings per share calculation for  1996,
          1995   and   1994  were  12,255,635,  12,029,908,  and  12,002,135,
          respectively,  while  the shares used in  the  earnings  per  share
          calculation  for  1996, 1995 and 1994 were 13,727,960,  12,969,701,
          and 13,166,363, respectively.
<TABLE>
<CAPTION>
          Supplemental cash flow disclosures are as follows:
            Cash Paid During The Year For:
<S>                             <C>         <C>           <C>
                                    1996        1995           1994
               Income Taxes      $1,586,000  $  430,000    $   157,000
               Interest                   -  $   29,000    $    31,000
</TABLE>
                                       18
<PAGE>
 NOTE C.  INVENTORIES
          Inventories  are stated at the lower of cost or market,  determined
          on  the  first-in,  first-out  (FIFO)  basis.   Cost  utilized  for
          inventory  purposes  include  labor,  material,  and  manufacturing
          overhead.
          The major components of inventories are as follows:
<TABLE>
<CAPTION>
<S>                                      <C>               <C>
                                               March 31,
                                         1996               1995
               Finished  products     $  685,000         $  888,000
               Work-in-process           414,000            106,000
               Raw materials             825,000            587,000
                                      $1,924,000         $1,581,000
                                      ==========         ==========
</TABLE>
NOTE D.   PROPERTY, PLANT AND EQUIPMENT
          Property, plant and equipment consist of the following:
<TABLE>
<CAPTION>
<S>                                  <C>             <C>
               
                                               March 31,
                                         1996            1995
             Land                     $   91,000      $   91,000
             Buildings                   594,000         569,000
             Machinery and equipment   1,115,000       1,003,000
             Laboratory equipment        276,000         213,000
             Furniture and fixtures      106,000          81,000
             Vehicles                     26,000          26,000
             Construction in progress    259,000          23,000
                                       2,467,000       2,006,000
             Less:
             Accumulated depreciation  1,156,000          954,000
                                      $1,311,000       $1,052,000
                                      ==========       ==========
</TABLE>
                                        19
<PAGE>
NOTE E.   INCOME TAXES
          In  the  first  quarter of fiscal year 1994,  the  Company  adopted
          Statement  of  Financial Accounting Standards No. 109  (SFAS  109),
          Accounting for Income Taxes.  Under the asset and liability  method
          prescribed  by  SFAS 109, deferred income taxes are recognized  for
          the  future  tax consequences attributable to temporary differences
          between  the financial statement carrying amounts and tax  balances
          of  existing  assets  and  liabilities.  Deferred  tax  assets  and
          liabilities are measured using the enacted rates expected to  apply
          to  taxable  income in the years which those temporary  differences
          are expected to be recovered or settled.
          
          The  provision  for  income taxes in fiscal  1996,  1995  and  1994
          include  deferred  tax  credits  of $16,000,  $22,000  and  $11,000
          respectively.
          
          Total  deferred tax assets and liabilities at March 31, 1996,  were
          $59,000  and $10,000, respectively. Total deferred tax  assets  and
          liabilities   at  March  31,  1995,  were  $60,000   and   $27,000,
          respectively.   There  were no individually  significant  temporary
          differences at March 31, 1996 or 1995.
          
          The reconciliation between the effective tax rate and the statutory
          federal income tax rate is as follows:
<TABLE>
<CAPTION>
<S>                                                   <C>     <C>     <C>
          
                                                       1996    1995    1994
            Statutory federal tax rate                 34.0%   34.0%   34.0%
            Federal net operating loss utilized           -    (5.9)% (34.0)%
            Federal general business credit utilized      -    (6.9)%     -
            Federal alternative minimum tax (credit)      -    (1.7)%   1.4%
            State taxes                                 2.0%    4.4%    8.6%
                                                       -----   -----   -----
            Effective tax rate                         36.0%   23.9%   10.0%
                                                       =====   =====   =====
</TABLE>

NOTE F.   LINE OF CREDIT
          The  Company  has a line of credit available with  a  bank  in  the
          amount  of $1 million with an applicable interest rate of  9.0%  at
          March 31, 1996.  There were no amounts outstanding under this  loan
          at the end of the fiscal year.  This line of credit is renewable on
          an annual basis.
                                             20
<PAGE>
NOTE G.   SHAREHOLDERS' EQUITY
          Under  the  Amended and Restated 1990 Stock Option  Plan  1,600,000
          shares  have  been  authorized for issuance.  A  total  of  589,790
          options  have been exercised and 46,910 options have been  canceled
          as of March 31, 1996 under the plan since its inception.
          
          The 1995 Incentive Compensation Plan authorized 902,000 shares of
          the Company's stock to be issued.  This Plan is the successor to
          the Amended and Restated 1990 Stock Option Plan.  No further grants
          will be made under the original Plan.

          Activity under the Amended and Restated 1990 Stock Option Plan  and
          1995  Incentive Compensation Plan over the last three fiscal  years
          is summarized as follows:
<TABLE>
<CAPTION>
<S>                                     <C>      <C>            <C>
                                                         Option Price
                                                     ______________________
                                         Number       Per
                                        of Shares    Share           Total
         ___________________________________________________________________
         Options outstanding at
          March 31, 1993                 686,390  $ .66 - 1.25   $   622,000
           Options granted               271,960       1.72          468,000
           Options exercised             (55,731)   .61 - 1.25       (54,000)
           Options canceled                    -             -             -
          Options outstanding at
           March 31, 1994                902,619    .61 - 1.72     1,036,000
            Options granted              200,000       2.22          444,000
            Options exercised            (43,120)   .61 - 1.25       (37,000)
            Options canceled                   -             -             -
           Options outstanding at
            March 31, 1995             1,059,499    .61 - 2.22     1,443,000
             Options granted             269,000    .30 - 2.84       718,000
             Options exercised          (450,789)   .30 - 2.22      (382,000)
             Options canceled             (5,750)  2.22 - 2.84       (15,000)
            Options outstanding at
             March 31, 1996              871,960  $ .30 - 2.84    $1,764,000
                                       =========  ============    ==========
            Options becoming exercisable
             during fiscal 1996          239,980  $ .30 - 2.22    $  457,000
                                       =========  ============    ==========
</TABLE>
          As  of March 31, 1996, options to purchase 512,710 shares of Common
          Stock were exercisable under these Plans.

                                           21
<PAGE>
NOTE G.   SHAREHOLDERS' EQUITY (CONTINUED)
          On  March 27, 1995, JB Partners exercised the warrant purchased  as
          part  of  a stock and warrant sale in 1991.  The exercise price  of
          the 5-year, nontransferable warrant was $1.00 per share and the net
          proceeds to the Company were $993,000.
          
          On  January 7, 1992, the Board of Directors authorized the issuance
          of a warrant to Page E. Golsan, III.  Mr. Golsan is a member of the
          Board  of  Directors.  The warrant is for the  purchase  of  up  to
          25,000 shares of the Company's common stock at a purchase price  of
          $1.81  per share, the market value on January 7, 1992.  The warrant
          expires on December 31, 1996.
          
          On February 5, 1992, the Board of Directors authorized the issuance
          of  a warrant to Emanuel and Company.  The warrant is for retention
          of  Emanuel  and Company as the Company's investment  banker.   The
          warrant  is  for  the purchase of 100,000 shares of  the  Company's
          stock at an exercise price of $2.22 per share, the market value  on
          February 5, 1992.  The warrant expires on December 31, 1996.
          
          The  Financial  Accounting Standards Board  has  issued  SFAS  123,
          "Accounting for Stock-Based Compensation" which establishes a  fair
          value  approach  to  measuring  compensation  expense  related   to
          employee  stock  plans.  In fiscal 1997, the  Company  must  either
          account for awards granted under employee stock plans after January
          1,  1995  under  the  provisions of SFAS 123  or  provide  detailed
          disclosures in lieu of adoption.  The Company plans to  only  adopt
          the disclosure provisions of SFAS 123.
          

NOTE H.   401(k) PROFIT SHARING PLAN
          The  Company established a 401(k) Profit Sharing Plan on  April  1,
          1992.  This plan is offered to eligible employees, who may elect to
          contribute  up  to  15%  of compensation, and  includes  a  Company
          matching  contribution of $.50 for each $1.00  contributed  by  the
          employee  up  to  10%  of compensation.  The  Company  contribution
          becomes fully vested for each employee after 5 years of employment.
          The  Company matching contribution for fiscal years 1996, 1995, and
          1994  was $42,000, 37,000 and $32,000, respectively.  Beginning  in
          April 1996, the Company has amended the Plan to change the matching
          contribution to $.50, $.75 and $1.00 for each $1.00 contributed  up
          to  10% of compensation corresponding to length of service with the
          Company.
          
NOTE I.   SEGMENT INFORMATION
          Significant Customers:  During fiscal year 1996, two customers
          accounted for 23% and 11% of revenues. During fiscal year 1995, two
          customers accounted for 27% and 11% of revenues.  During fiscal
          year 1994, two customers accounted for 22% and 11% of total
          revenues.

          The following table reflects foreign sales and percent of total 
          sales by country:
<TABLE>
<CAPTION>
<S>                  <C>         <C>    <C>         <C>    <C>        <C>
                              1996               1995              1994

             Europe   $1,252,000  14.8%  $  762,000  14.2%  $  527,000  13.1%
              Japan   $  528,000   6.2%  $  258,000   4.8%  $  128,000   3.2%
</TABLE>
                                       22
<PAGE>
                                      
          ITEM 8.  CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON
                     ACCOUNTING AND FINANCIAL DISCLOSURE

Not applicable.
                                      
                                  PART III
                                      
       ITEM 9.  DIRECTORS, EXECUTIVE OFFICERS; COMPLIANCE WITH SECTION
                          16(a) OF THE EXCHANGE ACT

The  following table sets forth certain information concerning the  executive
officers and directors of the Company:
<TABLE>
<CAPTION>
<S>      <C>                   <C>   <C>
                                              
                  Name                      Age          Position
          M. ("Sreeni") Sreenivasan         47    President, Chief Executive
                                                  Officer and Director
          Philip L. Knutson                 46    Vice President of Research
                                                  and Development
          Charles B. Williams               49    Vice President of
                                                  Administration and
                                                  Finance, Chief Financial
                                                  Officer, Secretary and
                                                  Treasurer
          Paul C. Ahrens                    44    Chairman of the Board
          Howard L. Farkas                  72    Director
          Page E. Golsan, III               58    Director
</TABLE>
The following is a brief account of the business experience of each executive
officer and director of the Company.

M.  "Sreeni" Sreenivasan.  Mr. Sreenivasan has served as President and  Chief
Executive  Officer since March 31, 1995 and as Chief Operating  Officer  from
1990  through March 31, 1995.  Mr. Sreenivasan has also served as a  director
since  1995.  From 1988 to 1990 he was Executive Vice President  and  General
Manager  and from 1987 to 1988 he was Director of Manufacturing.  Previously,
he  worked  for Ruetgers-Nease Chemical Co. (bulk pharmaceuticals  and  other
fine   chemicals)  for  13  years  in  various  technical  and  manufacturing
management  capacities, including 7 years as Plant Manager of their  Augusta,
Georgia  plant.   Mr.  Sreenivasan received his M.S. in Chemical  Engineering
from Bucknell University and his M.B.A. from Penn State University.

Philip  L.  Knutson,  Ph.D.   Dr. Knutson has served  as  Vice  President  of
Research and Development since 1988.   Dr. Knutson is responsible for process
development,  "kilo  lab" production and production support.   From  1986  to
1988, he was a Senior Research Chemist with the Company.  Prior thereto,  Dr.
Knutson was a Senior Research  Chemist at Ash Stevens, Inc. in Detroit, 
Michigan for 7 years.   He received his B.A. degree from Luther College, 
Decorah, Iowa and his M.A.  and Ph.D. in Organic Chemistry from the 
University of Missouri - Columbia.

Charles  B.  Williams.   Mr.  Williams  has  served  as  Vice  President   of
Administration and Finance and Treasurer since 1990.  In 1995, he became  the
Secretary  of  the Company and in  July 1996, he also became Chief  Financial
Officer.    Mr.  Williams  is  responsible  for  accounting,  administration,
finance,  personnel and information systems.  From 1988 to 1990, Mr. Williams
served  as  the  Controller.  Prior thereto, he was  Controller  for  White's
Electronics, Inc. of Sweet Home, Oregon for 5 years.  His responsibilities at
White's  Electronics  included  accounting, data  processing,  personnel  and
                                  23
<PAGE>
finance.  From  1976  to  1983,  he  held several  accounting  and  financial
positions  with  Teledyne  Wah Chang, a metals producer  in  Albany,  Oregon.
Mr.  Williams  earned  his  B.S. in Economics and M.B.A.  from  Oregon  State
University.

Paul  C.  Ahrens.   Mr. Ahrens has been a Director of the Company  since  its
inception in 1981 and became Chairman of the Board effective March 31,  1995.
Mr. Ahrens, a founder of the Company, served as President and Chief Executive
Officer from 1989 through March 1995.  From 1981 through 1989 he was the Vice
President  of  Technology.  He also served as Secretary of the  Company  from
1981 through 1995.  From 1979 to 1980, Mr. Ahrens served as Vice President of
Engineering  of  Colorado  Organic  Chemical  Company,  an  organic  chemical
manufacturing  company  located in Commerce City, Colorado.   Prior  thereto,
Mr.  Ahrens  spent five years with Allied Chemical and CIBA-Geigy in  various
engineering and research capacities.  Mr. Ahrens holds B.S. and M.S.  degrees
in Chemical Engineering from M.I.T.

Howard  L. Farkas.  Mr. Farkas has served as a Director of the Company  since
1985.  He is the President of Farkas Group, Inc., successor to Farkas Realty,
which  is  engaged in general real estate brokerage and management activities
since 1981 and a managing director in Manistee Gas Limited Liability Company,
which  is  in  the  gas  production  and processing  business.   Since  1986,
Mr.  Farkas  has  also  served as Secretary and  a  Director  of  Acquisition
Industries,   Inc.,  a  publicly  owned  acquisition  and   merger   company.
Mr.  Farkas  serves as the Chairman of the Board of Logic  Devices,  Inc.,  a
Sunnyvale,  California  company specializing in CMOS digital  signal  process
semiconductor  and SRAM chips, and as a Director in various natural  resource
and  other  commercial companies.  Mr. Farkas is also  a  vice  president  of
G.A.S.  Corp., which is a general partner of an Oklahoma limited partnership,
Gas  Acquisition  Services,  which filed for  bankruptcy  under  Chapter  11.
Though  not presently in public or private practice, he has been a  certified
public  accountant since 1951.  Mr. Farkas received a B.S.  (B.A.)  from  the
University of Denver.

Page  E.  Golsan, III.  Mr. Golsan has served as a Director  of  the  Company
since  1991.   He is a principal of Golsan Management Company, an  investment
advisory  company.  From 1990 to 1992, Mr. Golsan was a senior  advisor  with
Bane  Barham & Holloway, registered investment advisors under the  Investment
Advisor  Act  of  1940.  Since 1990 Mr. Golsan has been President  and  Chief
Executive  Officer of Bridgetown Capital, Inc., an investment company.   From
1987 to 1989 he was the Executive Vice President of Calumet Industries, Inc.,
Chicago,  Illinois  (manufacturer and marketer of petro-chemicals  and  other
fine  chemicals).   Prior to 1987, he was the President and  Chief  Operating
Officer  of  the K&W Products Division (specialty chemical manufacturing)  of
Berkshire  Hathaway, Inc.  Mr. Golsan also currently serves as a director  of
Panef Corporation, Milwaukee, Wisconsin, (a privately-held pharmaceutical and
specialty  chemical packaging company).  Mr. Golsan holds an M.A. in  Finance
from Claremont Graduate School of Business and a Doctorate in Pharmacy and  a
B.A.  in  Chemistry  and  Zoology,  both  from  the  University  of  Southern
California.

In connection with the issuance of common stock and a warrant to JB Partners,
an  investment partnership affiliated with Peter B. Cannell & Co. Inc., a New
York  investment  management firm, the directors and officers  of  Synthetech
(other than Mr. Golsan who was not a director at the time) have entered  into
an agreement to vote shares of Synthetech owned by them for the election of a
nominee to the Board of Directors selected by JB Partners.  Unless terminated
earlier under certain circumstances, this agreement will continue until 1998.
JB  Partners  has advised Synthetech that it will not select  a  nominee  for
election at the upcoming Annual Meeting of Shareholders.
                                 24                                
<PAGE>
                      ITEM 10.  EXECUTIVE COMPENSATION

Summary of Cash and Certain Other Compensation

The   following   table  provides  certain  summary  information   concerning
compensation paid by the Company to those persons who were at March 31, 1996,
the  Company's Chief Executive Officer, the two other executive  officers  of
the  Company  and one other Company employee whose salary and bonus  exceeded
$100,000  during the last fiscal year (the "Named Persons")  for  the  fiscal
years ended March 31, 1996, 1995 and 1994:

<TABLE>
<CAPTION>

<S><C>                 <C>       <C>        <C>          <C>         <C>
                                Summary Compensation Table
                                                      Long-Term    All Other
                       Annual Compensation      Compensation  Compensation
    Name and                                            
    Principal Position  Year(1)  Salary($) Bonus($)  Stock Options(#)  ($)(2)                         

    M. ("Sreeni")        1996      132,000   60,000       66,000       3,203
    Sreenivasan          1995      113,400   28,000       52,000       4,688
    President &          1994      108,000    7,500       73,000       4,827
    Chief Executive                                    
    Officer                
                       
    Philip L.            1996       95,000   43,000       50,000       3,531
    Knutson              1995       87,150   24,000       40,000       4,672
    Vice President       1994       83,000    7,000       56,240       4,755
    of Research and
    Development

    Charles B.           1996       75,000   35,000       34,000       3,122
    Williams             1995       67,200   20,000       25,000       3,130
    Vice President       1994       64,000    6,000       34,720       3,800
    of Finance and
    Administration

    Jay A. Bouwens       1996       74,000   35,000       15,000       1,863
    Director of          1995       34,149(3) 8,750(3)       ---         ---
    Manufacturing         
</TABLE>
_______________________
(1)   Fiscal year ended March 31.
(2)Represents  Company contributions to the account  of  the  Named  Persons
 under the Company's 401(k) plan.
(3)Mr. Bouwens was hired in September 1994.
                                      25
<PAGE>
Stock Option Grants in Last Fiscal Year

The  following table provides information, with respect to the Named Persons,
concerning the grant of stock options during fiscal year 1996.
<TABLE>
<CAPTION>
<S>             <C>      <C>       <C>       <C>     <C>
               Stock Options Grants in the Last Fiscal Year(1)
                            % of                         
                           Total              Fair       
                 Options  Options  Exercise   Market      
Name             Granted  Granted     or      Value   Expiration
                   (#)       to      Base    at Date   
                          Employe   Price      of      Date
                           es in    ($/Sh)  Grant(3)
                           Fiscal              
                          Year(2)             ($)
____________     ______   ______    _____     _____     ____ 
M. ("Sreeni")    66,000     25%     $2.84    $2.84     May 2000
Sreenivasan                                            
Philip L.        50,000     19%     $2.84    $2.84     May 2000
Knutson                                                
Charles B.       34,000     13%     $2.84    $2.84     May 2000
Williams                                               
Jay A. Bouwens   10,000      4%     $2.84    $2.84     May 2000
                  5,000      2%     $0.30    $2.91     May 2005                                                       
</TABLE>
(1)   The Company has not granted any stock appreciation rights (SARs).
(2)   Based  on  an  aggregate  of  269,000 options  being  granted  to  all
      employees during the fiscal year ended March 31, 1996.
(3)   The average of closing bid and asked prices on the date of grant.
                                  26
<PAGE>

Stock  Option Exercises in Last Fiscal Year and Fiscal Year-End Stock  Option
Values

The  following table provides information, with respect to the Named Persons,
concerning  the options granted to them during the last fiscal year  and  the
options held by them at March 31, 1996.

<TABLE>
<CAPTION>
<S>       <C>             <C>         <C>       <C>        <C>         <C>
                              
                           Fiscal Year End Stock Option Value
                Shares                               
                Acquired                               
                   on     Value     Number of       Value of
                Exercise  Realized  Unexercised   Unexercised In-
Name                                Options at     the-Money
                  (#)    ($)       Fiscal Year     Options at
                                       End         Fiscal Year
                                                End ($)(1)
                               Exerci-  Unexer- Exerci- Unexer-
                                sable  cisable  sable  cisable
                                                       
M. ("Sreeni")   145,200  $518,232  160,000  92,000 $945,600  $543,720
Sreenivasan   
Philip L.       117,800  $425,650  123,240  70,000 $728,348  $413,700
Knutson    
Charles B.       70,400  $251,264   76,220  46,500 $450,460  $274,815
Williams    
Jay A. Bouwens      ---       ---    2,500  12,500  $14,775   $73,875
   
(1)    The average of the closing bid and asked prices of the Common Stock on
 March 31, 1996 was $5.91.
</TABLE>

Compensation of Directors

The Company's directors have not received an annual fee for their service as
directors in the past.  The Company reimburses directors for travel and other
out of pocket expenses of attending meetings.
                                    27
<PAGE>                                      
        ITEM 11.  SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND
                                 MANAGEMENT
                                      
                      PRINCIPAL OWNERS OF COMMON STOCK
The  following  table  sets forth the number of shares of  Common  Stock  and
percentage of outstanding shares of Common Stock of the Company owned  as  of
April  25,  1996, by persons who hold of record or are known to  beneficially
own  5% or more of the outstanding common stock of the Company, each director
of the Company, certain officers and all officers and directors as a group.

<TABLE>
<CAPTION>
<S><C>                         <C>                <C>   
    Name and Address of          Amount and       Percent
    Beneficial Owner              Nature of         of
                                 Beneficial        Class
                                 Ownership
    
    Paul C. Ahrens               1,551,491          11.5%
    1290 Industrial Way
    Albany, OR

    Michael A. Mitton              978,799           7.2%
    Suite 22                                     
    6300 Estate Frydenhoj
    416-1
    St. Thomas, U.S.V.I.

    M. ("Sreeni")                  641,100(1)        4.7%(2)
    Sreenivasan
    1290 Industrial Way
    Albany, OR

    Howard L. Farkas                50,000             *
    5460 South Quebec
    Street, Suite 300
    Englewood, CO

    Page E. Golsan, III             38,000(3)          *
    3205 Canterbury Drive,
    South
    Salem, OR

    JB Partners                  2,000,000          14.8%
    919 Third Avenue
    New York, NY

    Philip L. Knutson,             406,040(4)        3.0%(2)
    Ph.D.
    1290 Industrial Way
    Albany, OR

    Charles B. Williams            272,195(5)        2.0%(2)
    1290 Industrial Way
    Albany, OR

    Jay A. Bouwens                   7,500(6)          *
    1290 Industrial Way
    Albany, OR

    All Officers and             2,958,826(3)(4)(5) 21.1%(2)
    Directors as                                 
    a Group (6 persons)
</TABLE>
*less than 1%.
(1)  Includes 219,000 shares of common stock which Mr. Sreenivasan  has  the
 right  to acquire immediately or within sixty (60) days pursuant to employee
 stock options.  Excludes 33,000 shares of common stock issuable pursuant  to
 stock  options  held  by Mr. Sreenivasan which are not  exercisable  now  or
 within sixty (60) days.
(2)  The  denominator used in calculating the percentage  is  equal  to  the
 number of shares outstanding plus the number of shares the beneficial  owner
 (or  group  of  beneficial  owners) has a right to  acquire  immediately  or
 within sixty days pursuant to warrants or options.
(3)  Includes 25,000 shares of common stock issuable under a warrant.
                                     28
<PAGE>
(4)  Includes  168,240  shares of common stock which Dr.  Knutson  has  the
 right  to acquire immediately or within sixty (60) days pursuant to employee
 stock options.  Excludes 25,000 shares of common stock issuable pursuant  to
 stock  options held by Dr. Knutson which are not exercisable now  or  within
 sixty (60) days.
(5)  Includes   105,720 shares of common stock which Mr. Williams  has  the
 right  to acquire immediately or within sixty (60) days pursuant to employee
 stock  options.  Excludes 17,000   shares of common stock issuable  pursuant
 to  stock  options  held by Mr. Williams which are not  exercisable  now  or
 within sixty (60) days.
(6)  Includes 7,500 shares of common stock which Mr. Bouwens has the  right
 to  acquire immediately or within sixty (60) days pursuant to employee stock
 options.   Excludes 7,500 shares of common stock issuable pursuant to  stock
 options  held  by Mr. Bouwens which are not exercisable now or within  sixty
 (60) days.

                                      
          ITEM 12.  CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

In  March  1995,  Mr.  Ahrens resigned his positions as President  and  Chief
Executive Officer of the Company and became Chairman of the Board.   At  that
time,  Mr. Ahrens established an independent research and development  effort
to  investigate  new  applications of novel amino  acids  and  peptides.   In
connection with this transition, the Company and Mr. Ahrens entered  into  an
agreement  (the "Agreement") pursuant to which Mr. Ahrens agreed  to  provide
consulting services to the Company and to provide the Company with  licensing
rights  for  any  invention he might develop during the year  which  involved
amino acids and/or peptide-based materials (the "Amino Acid Technology").  In
March 1996, at the conclusion of the consulting services and research period,
Mr.  Ahrens  advised the Company that he did not intend to  continue  further
laboratory  research.  At that time, the Company requested,  and  Mr.  Ahrens
agreed  to,  an  Addendum to the Agreement to expand the Company's  licensing
rights  to any Amino Acid Technology that he may discover at any time in  the
future.   The  Company also agreed to reimburse Mr. Ahrens for  his  expenses
associated with his attendance on behalf of the Company at technical research
symposiums.

Certain  directors and officers of the Company have entered into an agreement
to vote shares of Synthetech Common Stock owned by them for the election of a
nominee to the Board of Directors selected by JB Partners, an investor in the
Company.  See Item 9.
                                      
                 ITEM 13.  EXHIBITS AND REPORTS ON FORM 8-K

(a)   Exhibits.   The following documents are filed as part  of  this  Annual
Report on Form 10-KSB:

3(i)(1)   Articles of Incorporation of Synthetech, Inc., as amended

3(ii)(7)  Bylaws of Synthetech, Inc., as amended

10.1(2,3) License  Agreement dated March 16, 1990 between Synthetech, Inc.  and
          Miwon Co. Ltd.

10.2(2,4) Supply  Agreement dated January 3, 1989 between Synthetech, Inc.  and
          Biomeasure, Incorporated

10.3(2,4) License Agreement dated January 3, 1989 between Synthetech, Inc.  and
          Biomeasure, Incorporated

10.4(2,+) Synthetech,  Inc.  Amended and Restated 1984 Stock Option  and  Bonus
          Plan

10.5(5,+) Synthetech, Inc. 1990 Stock Option Plan

10.6(6)   Stock  and  Warrant Purchase Agreement dated as of  August  23,  1991
          between  the  Company and JB Partners, a general  partnership  formed
          under the laws of the State of New York ("JB")

10.7      Amendment  No. 1 to Stock and Warrant Purchase Agreement between  the
          Company and JB dated as of March 26, 1996
                                      29
<PAGE>
10.8(6)   Agreement dated September 30, 1991 Among Certain Shareholders of  the
          Company

10.9(6)   Warrant  dated  January 7, 1992 to purchase 25,000 shares  of  Common
          Stock issued to Page E. Golsan, III

10.10(8)  Agreement  and Release dated as of March 31, 1995 between Synthetech,
          Inc. and Paul C. Ahrens (the "Ahrens Agreement")

10.11     Addendum to Ahrens Agreement dated as of April 1, 1996

10.12(8,+)1995 Incentive Compensation Plan

10.13   Warrant  dated  _______ to purchase 100,000 shares  of  common  stock
        issued to Emanuel & Company

10.14   U.S. Bank Line of Credit

23      Consent of Arthur Andersen LLP

__________________________

(+)    Management contract or compensatory plan.

(1)    Incorporated  by reference to the exhibits filed with registrant's  
       Annual Report on Form 10-K for the fiscal year ended March 31, 1991.

(2)  Incorporated  by reference to the exhibits filed with registrant's  Annual
     Report on Form 10-K for the fiscal year ended March 31, 1990.

(3)  Confidential treatment of certain portions of this document was granted by
     the Commission on May 7, 1990 (File No. 33-27566).

(4)  Confidential treatment of certain portions of this document was granted by
     the Commission on January 10, 1990 (File No. 33-27566).

(5)  Incorporated  by  reference  to  Exhibit  A  to  the  definitive  copy  of
     registrant's  Proxy Statement (dated October 23, 1990) for  the  1990  
     Annual Meeting of Shareholders.

(6)  Incorporated  by reference to the exhibits filed with registrant's  Annual
     Report on Form 10-K for the fiscal year ended March 31, 1992.

(7)  Incorporated  by reference to the exhibits filed with registrant's  Annual
     Report on Form 10-KSB for the fiscal year ended March 31, 1994.

(8)  Incorporated  by reference to the exhibits filed with registrant's  Annual
     Report on Form 10-KSB for the fiscal year ended March 31, 1995.



(b)  Reports on Form 8-K

None.
                                  30
<PAGE>

                             SIGNATURES

In  accordance  with Section 13 or 15(d) of the Exchange Act, the  registrant
has  duly  caused this report to be signed on its behalf by the  undersigned,
thereunto duly authorized.
                               
Date:  June 4, 1996            SYNTHETECH, INC.
                               (Registrant)
                               
                               
                               By  /s/  M. Sreenivasan
                                  M. ("Sreeni") Sreenivasan
                                  President and Chief
                                  Executive Officer

In accordance with the Exchange Act, this report has been signed below by the
following  persons on behalf of the registrant and in the capacities  and  on
the dates indicated.

     Signature                    Title                      Date
                                                       
/s/  M. Sreenivasan          President, Chief             May 31, 1996
 M. ("Sreeni") Sreenivasan   Executive Officer
                             (Principal Executive
                             Officer) and Director
                                                       

/s/  Charles B. Williams     Vice President of Finance    May 31, 1996
  Charles B. Williams        and Administration, Chief
                             Financial Officer,
                             Secretary and Treasurer
                             (Principal Financial
                             Officer and Principal
                             Accounting Officer)
                                                       

/s/  Paul C. Ahrens          Chairman of the Board        May 31, 1996
  Paul C. Ahrens
                                                       
                                                       
/s/  Howard L. Farkas        Director                     May 31, 1996
  Howard L. Farkas

                                                       
/s/  Page E. Golsan, III     Director                     May 31, 1996 
  Page E. Golsan, III

                                    31
<PAGE>






                              INDEX TO EXHIBITS
                                      
                                                              Sequential 
                                                                Page No.

3(i)(1)1   Articles of Incorporation of Synthetech, Inc., as
           amended

3(ii)(7)   Bylaws of Synthetech, Inc., as amended

10.1(2,3)  License  Agreement dated March 16,  1990  between
           Synthetech, Inc. and Miwon Co. Ltd.

10.2(2,4)  Supply  Agreement dated January 3,  1989  between
           Synthetech, Inc. and Biomeasure, Incorporated

10.3(2,4)  License  Agreement dated January 3, 1989  between
           Synthetech, Inc. and Biomeasure, Incorporated

10.4(2,+)  Synthetech, Inc. Amended and Restated 1984  Stock
           Option and Bonus Plan

10.5(5,+)  Synthetech, Inc. 1990 Stock Option Plan

10.6(6)    Stock and Warrant Purchase Agreement dated as  of
           August  23,  1991  between  the  Company  and  JB
           Partners, a general partnership formed under  the
           laws of the State of New York ("JB")

10.7    Amendment  No.  1  to Stock and Warrant  Purchase
        Agreement between the Company and JB dated as  of
        March 26, 1996                                              34

10.8(6) Agreement dated September 30, 1991 Among  Certain
        Shareholders of the Company

10.9(6) Warrant dated January 7, 1992 to purchase  25,000
        shares  of Common Stock issued to Page E. Golsan,III

10.10(8)Agreement and Release dated as of March 31,  1995
        between Synthetech, Inc. and Paul C. Ahrens  (the
        "Ahrens Agreement")

10.11   Addendum to Ahrens Agreement dated as of April 1,
        1996                                                        36

10.12(8,+)  1995 Incentive Compensation Plan

10.13   Warrant dated _______ to purchase 100,000  shares
        of common stock issued to Emanuel & Company                 38

10.14   U.S. Bank Line of Credit                                    44

24      Consent of Arthur Andersen LLP                              55

__________________________

(+)  Management contract or compensatory plan.
                                      32
<PAGE>
(1)  Incorporated  by reference to the exhibits filed with registrant's  Annual
     Report on Form 10-K for the fiscal year ended March 31, 1991.

(2)  Incorporated  by reference to the exhibits filed with registrant's  Annual
     Report on Form 10-K for the fiscal year ended March 31, 1990.

(3)  Confidential treatment of certain portions of this document was granted by
     the Commission on May 7, 1990 (File No. 33-27566).

(4)  Confidential treatment of certain portions of this document was granted by
     the Commission on January 10, 1990 (File No. 33-27566).

(5)  Incorporated  by  reference  to  Exhibit  A  to  the  definitive  copy  of
     registrant's  Proxy Statement (dated October 23, 1990) for  the  1990  
     Annual Meeting of Shareholders.

(6)  Incorporated  by reference to the exhibits filed with registrant's  Annual
     Report on Form 10-K for the fiscal year ended March 31, 1992.

(7)  Incorporated  by reference to the exhibits filed with registrant's  Annual
     Report on Form 10-KSB for the fiscal year ended March 31, 1994.
(8)  Incorporated by reference to the exhibits filed with registrant's Annual
     Report on Form 10-KSB for the fiscal year ended March 31, 1995.
                                       33

<PAGE>  
                                                                 Exhibit 10.7
                                                                to Form 10KSB
                                      
                                      
                                      
                             AMENDMENT NO. 1 TO
                    STOCK AND WARRANT PURCHASE AGREEMENT
     
     THIS AMENDMENT NO. 1 TO STOCK AND WARRANT PURCHASE AGREEMENT is made as
of the 27th day of March, 1996 by and between Synthetech, Inc., an Oregon
corporation (the "Company"), and JB Partners, a limited partnership formed
under the laws of the State of New York (the "Investor").
     
     THE PARTIES HEREBY AGREE AS FOLLOWS:
                                      
                          1.   Registration Rights.
     
     Section 6.1(c) of the Agreement shall be restated in its entirety as
follows:
          
          "(c) The term "Holder" means the Investor and any assignees
          pursuant to Section 6.7; and"
                                      
                       2.   Request for Registration.
     
     2.1  Section 6.2(a) of the Agreement shall be amended in its entirety as
follows:
          
          "(a) (i)  Subject to the terms and conditions set forth in
          Section 6, if the Company shall receive at any time after
          April 1, 1996, but on or before December 31, 1996, a written
          request from the Holder that the Company file a registration
          statement under the Act covering the registration of at least
          twenty percent (20%) of the Registrable Securities, the
          Company shall effect as soon as practicable, and in any event
          shall use its best efforts to effect within ninety (90) days
          of the receipt of such request, the registration under the Act
          of all Registrable Securities which the Holder requests to be
          so registered; provided that the Company shall be under no
          obligation to register the Registrable Securities pursuant to
          this Section 6 or otherwise if (A) Form S-3 is not then
          available for such registration, or (B) the Company during the
          period has already filed a Form S-3 with the SEC and permitted
          the Holders to participate in such registration.
          
               (ii) Subject to the terms and conditions set forth in
          Section 6, if the Company shall receive at any time after
          April 1, 1996, but on or before September 30, 1999, a written
          request from the Holder that the Company file a registration
          statement under the Act covering the registration of at least
          twenty percent (20%) of the Registrable Securities, the
          Company shall effect as soon as practicable, and in any event
          shall use its best efforts to effect within ninety (90) days
          of the receipt of such request, the registration under the Act
          of all Registrable Securities which the Holder requests to be
          so registered; provided that the Company shall be under no
          obligation to register the Registrable Securities pursuant to
          this Section 6 or otherwise if Form S-3 is not then available
          for such registration.
                                      34
<PAGE>     
               (iii)     Notwithstanding the foregoing, there shall be
          no registration right under this Section 6 for Registrable
          Securities which are eligible for immediate sale by the
          Holders pursuant to Rule 144 or its successor rule."
     
     2.2  Section 6.2(c) of the Agreement shall be amended in its entirety as
follows:
          
          "(c) The Company is obligated to effect no more than two (2)
          registrations pursuant to this Section 6.2."
                                      
                   3.   Assignment of Registration Rights.
     
     Section 6.7 of the Agreement shall be amended in its entirety as
follows:
          
          "The rights to cause the Company to register Registrable
          Securities pursuant to this Section 6 may not be assigned or
          transferred, except to the partners of the Investor in
          connection with the distribution of the Registrable Securities
          to such partners, provided that each partner agrees to be
          bound by the obligations of the Investor as set forth herein."
     
     IN WITNESS WHEREOF, the parties hereto have executed this Agreement on
the day and year first above written.
                          
                          SYNTHETECH, INC.
                          
                          
                          By:
                          Title:
                          
                          
                          
                          JB PARTNERS, a limited partnership formed
                          under the laws of the State of New York
                          
                          
                          By:
                            Peter B. Cannell,
                            Managing Partner

                                    35

<PAGE>

                                                                Exhibit 10.11
                                                                to Form 10KSB



                                      
                                  ADDENDUM

     
     This Addendum is entered into effective as of April 1, 1996 (the
"Effective Date") by and between Synthetech, Inc., an Oregon corporation (the
"Company") and Paul C. Ahrens ("Ahrens").
                                      
                                  RECITALS
     
     WHEREAS, the Company and Ahrens entered into an Agreement and Release
dated as of March 31, 1995 (the "Agreement").
     
     WHEREAS, the parties desire to enter into this Addendum to the
Agreement.
                                      
                                  AGREEMENT
     
     NOW, THEREFORE, in consideration of the premises and mutual covenants
contained herein and other good and valuable consideration, the receipt of
which each of the parties hereto acknowledge, it is hereby agreed as follows:
                                      
                1.   Reimbursement for Technology Conferences
     
     The Company agrees to reimburse Ahrens for reasonable expenses
associated with his attendance at technology conferences during the period
April 1, 1996 through March 31, 1997 (the Company's fiscal year).  Such
expenses shall include registration fees, travel, meals and lodging.
                                      
                            2.   Licensing Rights
     
     In consideration of the Company's reimbursement of expenses and other
good and valuable consideration, Ahrens agrees to extend the Company's right
to obtain licensing rights set forth in Section 3.5 of the Agreement to any
invention involving amino acid and/or peptide based materials as follows:
          
          The Company shall have the right upon written notice to Ahrens
     at any time now or in the future to obtain from Ahrens on
     commercially reasonable terms a worldwide, irrevocable, perpetual,
     exclusive license, with right to sublicense, to make, have made,
     use, sell and distribute any Invention (as defined below) and any
     product or service based on such Invention discovered by Ahrens at
     any time after March 31, 1995 which involves amino acids and/or
     peptide based materials (the "License").  The License shall include
     a royalty based on sales of the Invention (or products
     incorporating the Invention) of between 2% and 10%, inclusive, as
     mutually determined between the Company and Ahrens.  In the event
     the parties are unable to agree on a royalty rate or any other term
     or condition to the License, they shall submit the matter to
     binding arbitration to be conducted by an arbiter with appropriate
                                     36
<PAGE>
     industry and technology licensing knowledge and expertise.  If the
     parties cannot agree on such an individual within thirty (30) days
     after the delivery by one party to the other party of its or his
     written proposal naming such an arbiter (such delivery date
     hereinafter referred to as the "Initial Date"), then each party
     shall select one such arbiter within sixty (60) days after the
     Initial Date and those two arbiters shall select a third arbiter
     with such qualification within ninety (90) days after the Initial
     Date.  If either party fails to select an arbiter within the 60-day
     period after the Initial Date, the other party's selection shall be
     the sole arbiter.  For purposes of this Agreement, an "Invention"
     shall mean any discovery, development, improvement, design,
     process, procedure, machine, product, composition of matter,
     formula, computer program, technique or other invention, whether or
     not patentable or copyrightable, arising from Mr. Ahrens' research
     and investigation.
     
     IN WITNESS WHEREOF, the parties hereto have executed this Agreement on
the day and year first above written.
     
     

                              
                              SYNTHETECH, INC.
                              
                              
                              By:
Paul C. Ahrens                Name:
                              Title:
                              
                                  37                              

<PAGE>
       
                                                                Exhibit 10.13
                                                                to Form 10KSB



THIS WARRANT IS NONTRANSFERABLE.

No. WC-003                Warrant to Purchase 100,000 Shares of Common  Stock
                          (subject to adjustment)

                      WARRANT TO PURCHASE COMMON STOCK
                                     OF
                              SYNTHETECH, INC.


THE  COMMON STOCK ISSUABLE UPON EXERCISE HEREOF HAS NOT BEEN REGISTERED UNDER
THE  SECURITIES ACT OF 1933 OR ANY APPLICABLE STATE SECURITIES LAW.  THEY MAY
NOT BE SOLD, OFFERED FOR SALE, PLEDGED, HYPOTHECATED OR OTHERWISE TRANSFERRED
IN  THE  ABSENCE  OF A REGISTRATION STATEMENT IN EFFECT WITH RESPECT  TO  THE
SECURITIES  UNDER SUCH ACT OR LAWS OR AN OPINION OF COUNSEL  SATISFACTORY  TO
THE COMPANY THAT SUCH REGISTRATION IS NOT REQUIRED.
                      ________________________________
This certifies that, for value received, Emanuel and Company, a corporation
formed under the laws of the State of New York ("Holder"), is entitled,
subject to the terms set forth below, to purchase from Synthetech, Inc., an
Oregon corporation (the "Company"), One Hundred Thousand (100,000) shares of
Common Stock of the Company, as constituted on the date hereof, upon
surrender hereof, at the principal office of the Company referred to below,
with the exercise form attached hereto duly executed and other required
documents, and simultaneous payment therefor in lawful money of the United
States, at the Exercise Price as set forth in Section 2 below. The number,
character and Exercise Price of such shares of Common Stock are subject to
adjustment as provided below.  The term "Warrant" as used herein shall
include this Warrant, and any warrants delivered in substitution or exchange
therefor as provided herein.

This Warrant is issued in connection with the retention of the Holder as  the
corporation's investment banker.

1.    Term of Warrant.  Subject to the terms and conditions set forth herein,
this  Warrant  shall be exercisable, in whole (and not in part),  during  the
term  commencing on the date hereof. The purchase right represented  by  this
Warrant  shall  terminate on December 31, 1996, at 5 p.m.,  Portland,  Oregon
time.

2.    Exercise  Price.   The  Exercise Price at which  this  Warrant  may  be
exercised is $2.22 per share of Common Stock, as adjusted from time  to  time
pursuant to Section 10 hereof.

3.   Exercise of Warrant.
(a)  Procedure.  The purchase rights represented by this Warrant are
exercisable by the Holder in whole (and not in part), at any time, during the
term hereof as described in Section 1 above, by the delivery at the office of
the Company (or such other office or agency of the Company as it may
designate by notice in writing to the Holder at the address of the Holder
appearing on the books of the Company) of (i) this Warrant, (ii) the exercise
form annexed hereto duly completed and executed on behalf of the Holder,
(iii) the appropriate payment in cash or by check acceptable to the Company,
(iv) if requested by the Company, representations regarding the Holder's
sophistication, investment intent, acquisition for its own account and such
other matters requested, and (v) if requested by Company, an opinion of
counsel satisfactory to the Company that registration is not required under
the Federal or state securities laws.
(b)  Certificate.  This Warrant shall be deemed to have been exercised
immediately prior to the close of business on the date of its delivery, as
provided above, and the Holder shall be treated for all purposes as the
holder of record of such shares as of the close of business on such date.  As
promptly as practicable on or after such date and in any event within thirty
(30) days thereafter, the Company at its expense shall issue and deliver to
the Holder a certificate or certificates for the number of shares issuable
upon such exercise (the "Warrant Shares").
                                    38
<PAGE>
(c)  Securities Act Legend.  The Company may place conspicuously upon each
certificate representing the Warrant Shares a legend substantially in the
following form, the terms of which are agreed to by the Holder:
          
               "THESE SECURITIES ARE NOT REGISTERED UNDER THE SECURITIES
          ACT OF 1933 OR ANY APPLICABLE STATE LAW. THEY MAY NOT BE SOLD,
          OFFERED FOR SALE, PLEDGED, HYPOTHECATED OR OTHERWISE
          TRANSFERRED IN THE ABSENCE OF A REGISTRATION STATEMENT IN
          EFFECT WITH RESPECT TO THESE SECURITIES UNDER SUCH ACT OR
          LAWS, OR AN OPINION OF COUNSEL SATISFACTORY TO THE COMPANY
          THAT SUCH REGISTRATION IS NOT REQUIRED."

4.     No  Fractional  Shares  or  Scrip.   No  fractional  shares  or  scrip
representing  fractional shares shall be issued upon  the  exercise  of  this
Warrant.  In lieu of any fractional share to which the Holder would otherwise
be  entitled,  the Company shall make a cash payment equal  to  the  Exercise
Price multiplied by such fraction.

5.    Loss  of Warrant.  Upon receipt by the Company of satisfactory evidence
of  the loss, theft, destruction or mutilation of this Warrant and either (in
the  case of loss, theft or destruction) reasonable indemnification  and,  if
reasonably  requested by the Company, a bond satisfactory to the Company,  or
(in  the  case of mutilation) the surrender of this Warrant for cancellation,
the  Company  will execute and deliver to the Holder, without charge,  a  new
Warrant of like denomination.

6.    Limited  Rights  of Warrant Holder.  The Holder shall  not,  solely  by
virtue  of  being  the Holder of this Warrant, have any of the  rights  of  a
holder  of  Common Stock of the Company, either at law or equity, until  such
Warrant  shall have been duly exercised pursuant to Section 3 and the  Holder
shall  be deemed to be the holder of record of Warrant Shares as provided  in
this  Warrant, at which time the Holder shall be deemed the holder of  record
of such shares for all purposes.

7.    Validity and Reservation of Warrant Shares.  The Company covenants that
all  Warrant  Shares  will,  when  issued, be  validly  issued,  fully  paid,
nonassessable  and free of preemptive rights.  The Company  agrees  that,  as
long  as this Warrant may be exercised, the Company will have authorized  and
reserved  for issuance upon exercise of this Warrant a sufficient  number  of
Warrant Shares to provide for exercise in full of this Warrant.

8.   Transfer Restriction.
(a)  Warrant.  Neither this Warrant or any interest therein may be assigned,
sold, transferred, hypothecated or otherwise disposed of without the written
consent of the Company.
(b)  Warrant Shares.  The Warrant Shares may not be assigned, sold,
transferred, hypothecated or otherwise disposed of, except in compliance with
the provisions of the legend set forth in Section 3(c) hereof.

9.     Sale/Merger,   etc.    In  case  of  any  merger,   consolidation   or
reorganization  of  the Company with or into one or more other  corporations,
which  results in the holders of the Company's voting securities  immediately
prior  to  such  event  owning less than a majority interest  of  the  voting
securities of the surviving corporation immediately following such event,  or
in  the  case  of any stock issuance or any other transaction  or  series  of
related  transaction  in  which more than 50% of  the  voting  power  of  the
corporation  is  transferred,  or in case of any  sale,  lease,  transfer  or
conveyance  to another corporation of all or substantially all of the  assets
of  the Company, then in any such event, the Holder shall be given notice  of
such proposed action at approximately the same time and in substantially  the
same  manner  as the holders of the Company's Common Stock.  If the  proposed
action  is  approved  according to applicable law, the  Holder  shall  be  so
notified  in  writing by the Company by registered or certified mail,  or  by
overnight  delivery service, and thereupon, this Warrant, to the  extent  not
then  exercised, shall automatically become null and void on or  before  5:00
p.m., Portland, Oregon time, on the tenth day following the delivery of  such
notice (the "Notice").
                                      39
<PAGE>
10.   Adjustments.   The Exercise Price and the number of shares  purchasable
hereunder are subject to adjustment from time to time as follows:
(a)  Split, Subdivision or Combination of Shares.  If the Company at any time
while this Warrant, or any portion thereof, remains outstanding and unexpired
shall split, subdivide or combine the securities as to which purchase rights
under this Warrant exist, into a different number of securities of the same
class, the Exercise Price for such securities shall be proportionately
decreased in the case of a split or subdivision or proportionately increased
in the case of a combination.
(b)  Reclassification, etc.  If the Company, at any time while this Warrant,
or any portion thereof, remains outstanding and unexpired by reclassification
of securities or otherwise, shall change any of the securities as to which
purchase rights under this Warrant exist into the same or a different number
of securities of any other class or classes, this Warrant shall thereafter
represent the right to acquire such number and kind of securities as would
have been issuable as the result of such change with respect to the
securities that were subject to the purchase rights under this Warrant
immediately prior to such reclassification or other change and the Exercise
Price therefor shall be appropriately adjusted.
(c)  Number of Warrant Shares Adjusted.  After any adjustment of the Exercise
Price pursuant to Section 10(a) or 10(b), the number of Warrant Shares
issuable at the new Exercise Price shall be adjusted to the number obtained
by (i) multiplying the number of Warrant Shares issuable upon exercise of the
Warrant immediately before such adjustment by the Exercise Price in effect
immediately before such adjustment and (ii) dividing the product so obtained
by the new Exercise Price.
(d)  Certificate as to Adjustments.  Upon the occurrence of each adjustment
or readjustment pursuant to this Section 10, the Company at its expense shall
promptly compute such adjustment or readjustment in accordance with the terms
hereof and furnish to the Holder a certificate setting forth such adjustment
or readjustments.

11.  Registration Rights.
11.1  Certain Definitions.  As used in this Agreement, the following terms
shall have the meanings set forth below:
(a)  "Commission" shall mean the Securities and Exchange Commission or any
other federal agency at the time administering the Securities Act.
(b)  "Exchange Act" shall mean the Securities Exchange Act of 1934, as
amended, or any similar successor federal statute and the rules and
regulations thereunder, all as the same shall be in effect from time to time.
(c)  "Holder" shall mean Emanuel and Company.
(d)  "Registrable Securities" shall mean (i) shares of Common Stock issuable
upon exercise of this Warrant and (ii) any Common Stock issued as a dividend
or other distribution with respect to or in exchange for or in replacement of
the shares referenced in (i) above, provided, however, that Registrable
Securities shall not include any shares of Common Stock which have previously
been registered or which have been sold to the public.
(e)  The terms "register," "registered" and "registration" shall refer to a
registration effected by preparing and filing a registration statement in
compliance with the Securities Act and applicable rules and regulations
thereunder, and the declaration or ordering of the effectiveness of such
registration statement.
(f)  "Registration Expenses" shall mean all expenses incurred in effecting
any registration pursuant to this Agreement, including, without limitation,
all registration, qualification, and filing fees, printing expenses, escrow
fees, fees and disbursements of counsel for the Company, blue sky fees and
expenses, and expenses of any regular or special audits incident to or
required by any such registration, but shall not include Selling Expenses and
fees and disbursements of counsel for the Holder (but excluding the
compensation of regular employees of the Company, which shall be paid in any
event by the Company).
(g)  "Securities Act" shall mean the Securities Act of 1933, as amended, or
any similar successor federal statute and the rules and regulations
thereunder, all as the same shall be in effect from time to time.
(h)  "Selling Expenses" shall mean all underwriting discounts and selling
commissions applicable to the sale of Registrable Securities.
11.2 Company Registration
(a) If the Company shall determine to register any of its securities either
for its own account or the account of a security holder or holders other than
a registration relating solely to employee benefit plans, the Company will:
     (i)  promptly give to Holder written notice thereof; and
     (ii)  use its best efforts to include in such registration (and any
related qualification under blue sky laws or other compliance), except as set
forth in Section 11.2(b) below, and in any underwriting involved therein, all
the Registrable Securities specified in a written request or requests, made
by Holder within twenty (20) days after the written notice from the Company
described in clause (i) above is given. Such written request may specify all
or a part of a Holder's Registrable Securities.
(b) If the registration of which the Company gives notice is for a registered
public offering involving an underwriting, the Company shall so advise Holder
as a part of the written notice given pursuant to Section 11.2(a)(i). In such
event, the right of Holder to registration pursuant to this Section shall be
conditioned upon Holder's participation in such underwriting and the
inclusion of Holder's Registrable Securities in the underwriting to the
extent provided herein. If Holder proposes to distribute the Registrable
Securities through such underwriting, it shall (together with the Company and
the other holders of securities of the Company with registration rights to
participate therein distributing their securities through such underwriting)
enter into an underwriting agreement in customary form with the
representative of the underwriter or underwriters selected by the Company.
                                   40
<PAGE>
Notwithstanding any other provision of this Section 11.2, if the
representative of the underwriters advises the Company in writing that
marketing factors require a limitation on the number of shares to be
underwritten, the representative may (subject to the limitations set forth
below) exclude all Registrable Securities from, or limit the number of
Registrable Securities to be included in, the registration and underwriting.
The Company shall so advise all holders of securities requesting
registration, and the number of shares of securities that are entitled to be
included in the registration and underwriting shall be allocated first to the
Company for securities being sold for its own account and thereafter as set
forth in Section 11.7.  If any person does not agree to the terms of any such
underwriting, he shall be excluded therefrom by written notice from the
Company or the underwriter.  Any Registrable Securities or other securities
excluded or withdrawn from such underwriting shall be withdrawn from such
registration.
If shares are so withdrawn from the registration or if the number of shares
of Registrable Securities to be included in such registration was previously
reduced as a result of marketing factors, the Company shall then offer to all
persons who have retained the right to include securities in the registration
the right to include additional securities in the registration in an
aggregate amount equal to the number of shares so withdrawn, with such shares
to be allocated among the persons requesting additional inclusion in
accordance with Section 11.7 hereof.
11.3 Expenses of Registration.  All Registration Expenses incurred in
connection with any registration, qualification or compliance pursuant to
Section 11.2 hereof and reasonable fees of one counsel for the selling
stockholders shall be borne by the Company.  All Selling Expenses relating to
the Registrable Securities so registered shall be borne by Holder pro rata on
the basis of the number of shares of securities so registered on its behalf.
11.4 Indemnification.
(a) The Company will indemnify Holder, each of its officers, directors and
partners, legal counsel, and accountants and each person controlling Holder
within the meaning of Section 15 of the Securities Act, with respect to which
registration, qualification, or compliance has been effected pursuant to this
Section 11, and each underwriter, if any, and each person who controls within
the meaning of Section 15 of the Securities Act any underwriter, against all
expenses, claims, losses, damages, and liabilities (or actions, proceedings,
or settlements in respect thereof) arising out of or based on any untrue
statement (or alleged untrue statement) of a material fact contained in any
prospectus, offering circular, or other document (including any related
registration statement, notification, or the like) incident to any such
registration, qualification, or compliance, or based on any omission (or
alleged omission) to state therein a material fact required to be stated
therein or necessary to make the statements therein not misleading, or any
violation by the Company of the Securities Act or any rule or regulation
thereunder applicable to the Company and relating to action or inaction
required of the Company in connection with any such registration,
qualification, or compliance, and will reimburse Holder, each of its
officers, directors, partners, legal counsel, and accountants and each person
controlling Holder, each such underwriter, and each person who controls any
such underwriter, for any legal and any other expenses reasonably incurred in
connection with investigating and defending or settling any such claim, loss,
damage, liability, or action, provided that the Company will not be liable in
any such case to the extent that any such claim, loss, damage, liability, or
expense arises out of or is based on any untrue statement or omission based
upon written information furnished to the Company by Holder or such
underwriter and stated to be specifically for use therein.  It is agreed that
the indemnity agreement contained in this Section 11.4(a) shall not apply to
amounts paid in settlement of any such loss, claim, damage, liability, or
action if such settlement is effected without the consent of the Company
(which consent has not been unreasonably withheld).
(b) Holder will, if Registrable Securities held by it are included in the
securities as to which such registration, qualification, or compliance is
being effected, indemnify the Company, each of its directors, officers,
partners, legal counsel, and accountants and each underwriter, if any, of the
Company's securities covered by such a registration statement, each person
who controls the Company or such underwriter within the meaning of Section 15
of the Securities Act, and each other stockholder, and each of their
officers, directors, and partners, and each person controlling such other
stockholder, against all claims, losses, damages and liabilities (or actions
in respect thereof) arising out of or based on any untrue statement (or
alleged untrue statement) of a material fact contained in any such
registration statement, prospectus, offering circular, or other document, or
any omission (or alleged omission) to state therein a material fact required
to be stated therein or necessary to make the statements therein not
misleading, and will reimburse the Company and other stockholders, directors,
officers, partners, legal counsel, and accountants, persons, underwriters, or
control persons for any legal or any other expenses reasonably incurred in
connection with investigating or defending any such claim, loss, damage,
liability, or action, in each case to the extent, but only to the extent,
that such untrue statement (or alleged untrue statement) or omission (or
alleged omission) is made in such registration statement, prospectus,
offering circular, or other document in reliance upon and in conformity with
written information furnished to the Company by the Holder and stated to be
specifically for use therein provided, however, that the obligations of the
Holder hereunder shall not apply to amounts paid in settlement of any such
claims, losses, damages, or liabilities (or actions in respect thereof) if
such settlement is effected without the consent of the Holder (which consent
shall not be unreasonably withheld).
(c) Each party entitled to indemnification under this Section 11.4 (the
"Indemnified Party") shall give notice to the party required to provide
indemnification (the "Indemnifying Party") promptly after such Indemnified
Party has actual knowledge of any claim as to which indemnity may be sought,
and shall permit the Indemnifying Party to assume the defense of such claim
or any litigation resulting therefrom, provided that counsel for the
Indemnifying Party, who shall conduct the defense of such claim or any
litigation resulting therefrom, shall be approved by the Indemnified Party
(whose approval shall not unreasonably be withheld), and the Indemnified
Party may participate in such defense at such party's expense, and provided
further that the failure of any Indemnified Party to give notice as provided
herein shall not relieve the Indemnifying Party of its obligations under this
Section 11.4, to the extent such failure is not prejudicial.  No Indemnifying
                                  41
<PAGE>
Party, in the defense of any such claim or litigation, shall, except with the
consent of each Indemnified Party, consent to entry of any judgment or enter
into any settlement that does not include as an unconditional term thereof
the giving by the claimant or plaintiff to such Indemnified Party of a
release from all liability in respect to such claim or litigation.  Each
Indemnified Party shall furnish such information regarding itself or the
claim in question as an Indemnifying Party may reasonably request in writing
and as shall be reasonably required in connection with defense of such claim
and litigation resulting therefrom.
(d) If the indemnification provided for in this Section 11.4 is held by a
court of competent jurisdiction to be unavailable to an Indemnified Party
with respect to any loss, liability, claim, damage, or expense referred to
therein, then the Indemnifying Party, in lieu of indemnifying such
Indemnified Party hereunder, shall contribute to the amount paid or payable
by such Indemnified Party as a result of such loss, liability, claim, damage,
or expense in such proportion as is appropriate to reflect the relative fault
of the Indemnifying Party on the one hand and of the Indemnified Party on the
other in connection with the statements or omissions that resulted in such
loss, liability, claim, damage, or expense as well as any other relevant
equitable considerations.  The relative fault of the Indemnifying Party and
of the Indemnified Party shall be determined by reference to, among other
things, whether the untrue or alleged untrue statement of a material fact or
the omission to state a material fact relates to information supplied by the
Indemnifying Party or by the Indemnified Party and the parties' relative
intent, knowledge, access to information, and opportunity to correct or
prevent such statement or omission.
(e) Notwithstanding the foregoing, to the extent that the provisions on
indemnification and contribution contained in the underwriting agreement
entered into in connection with the underwritten public offering are in
conflict with the foregoing provisions, the provisions in the underwriting
agreement shall control.
11.5 Information by Holder.  Holder shall furnish to the Company such
information regarding Holder and the distribution of Registrable Securities
proposed by Holder as the Company may reasonably request in writing and as
shall be reasonably required in connection with any registration,
qualification, or compliance referred to in Section 11.
11.6 Transfer or Assignment of Registration Rights.  The rights to cause the
Company to register securities granted to Holder by the Company under
Section 11 may not be transferred or assigned by Holder.
11.7 Allocation of Registration Opportunities.  In any circumstance in which
all of the Registrable Securities and other shares of Common Stock of the
Company (including shares of Common Stock issued or issuable upon conversion
of shares of any currently unissued series of Preferred Stock of the Company)
with registration rights (the "Other Shares") requested to be included in a
registration on behalf of Holder or other selling stockholders cannot be so
included as a result of limitations of the aggregate number of shares of
Registrable Securities and Other Shares that may be so included, the number
of shares of Registrable Securities and Other Shares that may be so included
shall be determined in the sole discretion of the Company.
11.8 Delay of Registration.  Holder shall have no right to take any action to
restrain, enjoin, or otherwise delay any registration as the result of any
controversy that might arise with respect to the interpretation or
implementation of this Section 11.

12.  Miscellaneous.
(a)  Applicable Law.  THIS AGREEMENT SHALL BE GOVERNED BY AND CONSTRUED IN
ACCORDANCE WITH THE LAWS OF THE STATE OF OREGON AS SUCH LAWS ARE APPLIED TO
AGREEMENTS BETWEEN OREGON RESIDENTS ENTERED INTO AND TO BE PERFORMED ENTIRELY
WITHIN OREGON.
(b)  Headings.  The headings herein are for convenience only and are not part
of this Warrant and shall not affect the interpretation thereof.
(c)  Jurisdiction; Venue; Service.  The parties each consent to the venue and
jurisdiction of any state or federal court located in Multnomah County,
Oregon.  Each party agrees that service of process may be made upon it
wherever it can be located or by certified mail directed to its address for
notices under this Agreement.  This provision is permissive, not mandatory,
and each party reserves the right to bring any action, proceeding, or other
matter arising directly or indirectly hereunder against the other party
wherever they might be found or might otherwise be subject to jurisdiction.
IN WITNESS WHEREOF, SYNTHETECH, INC. has caused this Warrant to be executed
by its officer thereunto duly authorized.
Dated as of ____________________.
                          
                          SYNTHETECH, INC.
                          
                          
                          By:_________________________________
                             Paul C. Ahrens, President
                             Synthetech, Inc.
                             1290 Industrial Way
                             Albany, OR  97321

ACKNOWLEDGED AND AGREED TO
                                   42
<PAGE>
EMANUEL AND COMPANY

By:_____________________________
Title:__________________________


                          NOTICE OF EXERCISE
To: SYNTHETECH, INC.
(1)  The undersigned hereby elects to purchase 100,000 shares of Common Stock
of SYNTHETECH, INC., pursuant to the terms of the attached Warrant, and tenders
herewith, such other documents required to be delivered under the terms of 
the Warrant and payment of the purchase price for such shares in full.
(2)  In exercising this Warrant, the undersigned hereby confirms and
acknowledges that the shares of Common Stock to be issued upon conversion
thereof are being solely for the account of the undersigned and no as a 
nominee for any other party, and for unvestment, and that the undersigned 
will not offer, sell or otherwise dispose of any such shares of Common Stock 
except under circumstances that will not result in a violation of the 
Securities Act of 1933, as amended, or any state securities laws. 
(3)  Please issue a certificate or certificates representing said shares of
Common Stock in the name of the undersigned:

Date:____________________        EMANUEL AND COMPANY

                                 By:___________________
                                    (Name)
                                 Title:________________

                                    43

                                                                Exhibit 10.14
                                                                of Form 10KSB


                        COMMERCIAL SECURITY AGREEMENT

Borrower: SYNTHETECH, INC.         Lender:   United States National Bank of
Oregon
          1290 INDUSTRIAL WAY      Mid-Willamette Commercial Banking Center
               ALBANY, OR 97321         PL-7 Oregon Corporate Loan Servicing
                                   555 S. W. Oak
                                   Portland, OR 97204


THIS  COMMERCIAL SECURITY AGREEMENT is entered into between SYNTHETECH,  INC.
(referred  to below as "Grantor"); and United States National Bank of  Oregon
(referred to below as "Lender").  For valuable consideration, Grantor  grants
to  Lender  a  security interest in the Collateral to secure the Indebtedness
and  agrees  that Lender shall have the rights stated in this Agreement  with
respect  to the Collateral, in addition to all other rights which Lender  may
have by law.

DEFINITIONS.  The following words shall have the following meanings when used
in  this Agreement.  Terms not otherwise defined in this Agreement shall have
the  meanings attributed to such terms in the Uniform Commercial  Code.   All
references to dollar amounts shall mean amounts in lawful money of the United
States of America.

     Agreement.    The  word  "Agreement"  means  this  Commercial   Security
     Agreement,  as  this Commercial Security Agreement  may  be  amended  or
     modified  from  time to time, together with all exhibits  and  schedules
     attached to this Commercial Security Agreement from time to time.

     Collateral.   The  word  "Collateral"  means  the  following   described
     property  of  Grantor, whether now owned or hereafter acquired,  whether
     now existing or hereafter arising, and wherever located:

          All   chattel   paper,  accounts,  contract  rights   and   general
     intangibles

     In  addition, the word "Collateral" includes all the following,  whether
     now  owned  or  hereafter acquired, whether now  existing  or  hereafter
     arising, and wherever located:

     (a)   All  accessions, accessories, increases, and additions to and  all
     replacements of and substitutions for any property described above.

     (b)   All products and produce of any of the property described in  this
     Collateral section.

     (c)   All  accounts, contract rights, general intangibles,  instruments,
     rents,  monies, payments, and all other rights, arising out of  a  sale,
     lease,  or  other disposition of any of the property described  in  this
     Collateral section.

     (d)    All  proceeds  (including  insurance  proceeds)  from  the  sale,
     destruction, loss, or other disposition of any of the property described
     in this Collateral section.

     (e)   All records and data relating to any of the property described  in
     this  Collateral section, whether in the form of a writing,  photograph,
     microfilm,  microfiche,  or  electronic  media,  together  with  all  of
     Grantor's  right,  title, and interest in and to all  computer  software
     required  to utilize, create, maintain, and process any such records  or
     data on electronic media.

     Event of Default.  The words "Event of Default" mean and include without
     limitation  any of the Events of Default set forth below in the  section
     titled "Events of Default."

     Grantor.  The word "Grantor" means SYNTHETECH, INC., its successors  and
     assigns

     Guarantor.   The word "Guarantor" means and includes without  limitation
     each  and all of the guarantors, sureties, and accommodation parties  in
     connection with the Indebtedness.

                                        44
<PAGE>
     Indebtedness.  The word "Indebtedness" means the indebtedness  evidenced
     by  the  Note, including all principal and interest, together  with  all
     other  indebtedness  and  costs  and  expenses  for  which  Grantor   is
     responsible under this Agreement or under any of the Related  Documents.
     In  addition,  the  word "Indebtedness" includes all other  obligations,
     debts and liabilities, plus interest thereon, of Grantor, or any one  or
     more  of  them,  to  Lender,  as well as all claims  by  Lender  against
     Grantor,  or  any one or more of them, whether existing  now  or  later;
     whether  they  are voluntary or involuntary, due or not due,  direct  or
     indirect,  absolute  or contingent, liquidated or unliquidated;  whether
     Grantor  may  be  liable individually or jointly  with  others;  whether
     Grantor  may be obligated as guarantor, surety, accommodation  party  or
     otherwise;  whether recovery upon such indebtedness may be or  hereafter
     may  become  barred  by  any statute of limitations:  and  whether  such
     indebtedness may be or hereafter may become otherwise unenforceable.

     Lender.   The word "Lender" means United States National Bank of Oregon,
     its successors and assigns.

     Note.   The  word  "Note"  means  the note  or  credit  agreement  dated
     September 8, 1995, in the principal amount of $1,000,000.00 from Grantor
     to  Lender,  together with all renewals of, extensions of, modifications
     of, refinancings of, consolidations of and substitutions for the note or
     credit agreement.

     Related  Documents.   The  words "Related Documents"  mean  and  include
     without  limitation  all  promissory  notes,  credit  agreements,   loan
     agreements,  environmental agreements, guaranties, security  agreements,
     mortgages,  deeds  of trust, and all other instruments,  agreements  and
     documents,  whether  now or hereafter existing, executed  in  connection
     with the Indebtedness.

RIGHT  OF  SETOFF.   Grantor  hereby grants Lender a  contractual  possessory
security  interest  in  and hereby assigns, conveys, delivers,  pledges,  and
transfers  all  of  Grantor's right, title and interest in and  to  Grantor's
accounts  with  Lender  (whether checking, savings, or some  other  account),
including  all  accounts  held jointly with someone  else  and  all  accounts
Grantor  may open in the future, excluding however all IRA, Keogh, and  trust
accounts.   Grantor authorizes Lender, to the extent permitted by  applicable
law, to charge or setoff all Indebtedness against any and all such accounts.

OBLIGATIONS OF GRANTOR.  Grantor warrants and covenants to Lender as follows:

     Organization.  Grantor is a corporation which is duly organized, validly
     existing,  and in good standing under the laws of the state of Grantor's
     incorporation.   Grantor  has  its  chief  executive  office   at   1290
     INDUSTRIAL  WAY, ALBANY, OR 97321.  Grantor will notify  Lender  of  any
     change in the location of Grantor's chief executive office.

     Authorization.   The  execution,  delivery,  and  performance  of   this
     Agreement  by Grantor have been duly authorized by all necessary  action
     by  Grantor  and  do  not conflict with, result in a  violation  of,  or
     constitute  a  default  under  (a) any  provision  of  its  articles  of
     incorporation  or  organization, or bylaws, or any  agreement  or  other
     instrument binding upon Grantor or (b) any law, governmental regulation,
     court decree, or order applicable to Grantor.

     Perfection  of  Security  Interest.   Grantor  agrees  to  execute  such
     financing statements and to take whatever other actions are requested by
     Lender  to  perfect  and  continue Lender's  security  interest  in  the
     Collateral.  Upon request of Lender, Grantor will deliver to Lender  any
     and  all of the documents evidencing or constituting the Collateral, and
     Grantor  will note Lender's interest upon any and all chattel  paper  if
     not  delivered  to  Lender  for possession by  Lender.   Grantor  hereby
     appoints  Lender as its irrevocable attorney-in-fact for the purpose  of
     executing any documents necessary to perfect or to continue the security
     interest granted in this Agreement.  Lender may at any time, and without
     further authorization from Grantor, file a carbon, photographic or other
     reproduction of any financing statement or of this Agreement for use  as
     a  financing statement.  Grantor will reimburse Lender for all  expenses
     for  the  perfection and the continuation of the perfection of  Lender's
     security  interest  in  the Collateral.  Grantor  promptly  will  notify
     Lender  before any change in Grantor's name including any change to  the
     assumed  business  names  of Grantor.  This  is  a  continuing  Security
     Agreement and will continue in effect even though all or any part of the
     Indebtedness  is  paid  in full and even though for  a  period  of  time
     Grantor may not be indebted to Lender.

     No  Violation.   The execution and delivery of this Agreement  will  not
     violate any law or agreement governing Grantor or to which Grantor is  a
     party,  and its certificate or articles of incorporation and  bylaws  do
     not prohibit any term or condition of this Agreement.

     Enforceability of Collateral.  To the extent the Collateral consists  of
     accounts,  contract rights, chattel paper, or general  intangibles,  the
     Collateral is enforceable in accordance with its terms, is genuine,  and
     complies  with  applicable laws concerning form, content and  manner  of
     preparation and execution, and all persons appearing to be obligated  on
     the  Collateral have authority and capacity to contract and are in  fact
     obligated  as  they appear to be on the Collateral.   At  the  time  any
                                        45
<PAGE>
     account  becomes subject to a security interest in favor of Lender,  the
     account  shall  be a good and valid account representing an  undisputed,
     bona  fide  indebtedness incurred by the account debtor, for merchandise
     held  subject  to  delivery  instructions  or  theretofore  shipped   or
     delivered  pursuant  to a contract of sale, or for services  theretofore
     performed by Grantor with or for the account debtor; there shall  be  no
     setoffs  or  counterclaims against any such account;  and  no  agreement
     under  which any deductions or discounts may be claimed shall have  been
     made  with  the  account  debtor except those  disclosed  to  Lender  in
     writing.

     Removal  of  Collateral.  Grantor shall keep the Collateral (or  to  the
     extent  the Collateral consists of intangible property such as accounts,
     the records concerning the Collateral) at Grantor's address shown above,
     or  at such other locations as are acceptable to Lender.  Except in  the
     ordinary  course  of  its business, including the  sales  of  inventory,
     Grantor  shall  not  remove the Collateral from its  existing  locations
     without  the  prior written consent of Lender.  To the extent  that  the
     Collateral consists of vehicles, or other titled property, Grantor shall
     not  take  or  permit  any  action which would require  application  for
     certificates  of  title for the vehicles outside the  State  of  Oregon,
     without the prior written consent of Lender.

     Transactions  Involving  Collateral.   Except  for  inventory  sold   or
     accounts collected in the ordinary course of Grantor's business, Grantor
     shall  not sell, offer to sell, or otherwise transfer or dispose of  the
     Collateral.   Grantor shall not pledge, mortgage, encumber or  otherwise
     permit  the  Collateral  to be subject to any lien,  security  interest,
     encumbrance, or charge, other than the security interest provided for in
     this  Agreement,  without  the prior written consent  of  Lender.   This
     includes  security  interests even if junior in right  to  the  security
     interests  granted under this Agreement.  Unless waived by  Lender,  all
     proceeds  from  any disposition of the Collateral (for whatever  reason)
     shall  be held in trust for Lender and shall not be commingled with  any
     other  funds;  provided however, this requirement shall  not  constitute
     consent  by  Lender  to  any sale or other disposition.   Upon  receipt,
     Grantor shall immediately deliver any such proceeds to Lender.

     Title.  Grantor represents and warrants to Lender that it holds good and
     marketable  title  to the Collateral, free and clear of  all  liens  and
     encumbrances  except  for  the  lien of this  Agreement.   No  financing
     statement covering any of the Collateral is on file in any public office
     other  than  those which reflect the security interest created  by  this
     Agreement or to which Lender has specifically consented.  Grantor  shall
     defend  Lender's rights in the Collateral against the claims and demands
     of all other persons.

     Collateral  Schedules and Locations.  As often as Lender shall  require,
     and   insofar  as  the  Collateral  consists  of  accounts  and  general
     intangibles,  Grantor  shall  deliver  to  Lender  schedules   of   such
     Collateral, including such information as Lender may require,  including
     without limitation names and addresses of account debtors and agings  of
     accounts  and general intangibles.  Such information shall be  submitted
     for Grantor and each of its subsidiaries or related companies.

     Maintenance  and Inspection of Collateral.  Grantor shall  maintain  all
     tangible  Collateral  in good condition and repair.   Grantor  will  not
     commit or permit damage to or destruction of the Collateral or any  part
     of the Collateral.  Lender and its designated representatives and agents
     shall  have  the right at all reasonable times to examine, inspect,  and
     audit the Collateral wherever located.  Grantor shall immediately notify
     Lender of all cases involving the return, rejection, repossession,  loss
     or  damage  of  or  to  any Collateral; of any  request  for  credit  or
     adjustment  or  of  any  other  dispute  arising  with  respect  to  the
     Collateral;  and  generally of all happenings and events  affecting  the
     Collateral or the value or the amount of the Collateral.

     Taxes,  Assessments  and Liens.  Grantor will pay when  due  all  taxes,
     assessments  and  liens upon the Collateral, its use or operation,  upon
     this  Agreement,  upon  any  promissory note  or  notes  evidencing  the
     Indebtedness, or upon any of the other Related Documents.   Grantor  may
     withhold any such payment or may elect to contest any lien if Grantor is
     in  good  faith  conducting  an appropriate proceeding  to  contest  the
     obligation to pay and so long as Lender's interest in the Collateral  is
     not  jeopardized  in  Lender's  sole  opinion.   If  the  Collateral  is
     subjected  to a lien which is not discharged within fifteen  (15)  days,
     Grantor  shall  deposit with Lender cash, a sufficient corporate  surety
     bond  or other security satisfactory to Lender in an amount adequate  to
     provide  for  the  discharge  of  the lien  plus  any  interest,  costs,
     attorneys'  fees  or  other charges that could accrue  as  a  result  of
     foreclosure  or  sale of the Collateral.  In any contest  Grantor  shall
     defend  itself  and Lender and shall satisfy any final adverse  judgment
     before enforcement against the Collateral.  Grantor shall name Lender as
     an  additional  obligee under any surety bond furnished in  the  contest
     proceedings.

     Compliance   With  Governmental  Requirements.   Grantor  shall   comply
     promptly  with  all  laws,  ordinances, rules  and  regulations  of  all
     governmental authorities, now or hereafter in effect, applicable to  the
     ownership,  production, disposition, or use of the Collateral.   Grantor
     may  contest  in  good faith any such law, ordinance or  regulation  and
     withhold   compliance  during  any  proceeding,  including   appropriate
     appeals,  so  long as Lender's interest in the Collateral,  in  Lender's
     opinion, is not jeopardized.
                                       46
<PAGE>
     Hazardous  Substances.   Grantor  represents  and  warrants   that   the
     Collateral  never has been, and never will be so long as this  Agreement
     remains  a lien on the Collateral, used for the generation, manufacture,
     storage,  transportation,  treatment, disposal,  release  or  threatened
     release  of any hazardous waste or substance, as those terms are defined
     in the Comprehensive Environmental Response, Compensation, and Liability
     Act of 1980, as amended, 42 U.S.C. Section 9601, et seq. ("CERCLA"), the
     Superfund Amendments and Reauthorization Act of 1986, Pub. L. No. 99-499
     ("SARA"), the Hazardous Materials Transportation Act, 49 U.S.C.  Section
     1801,  et  seq., the Resource Conservation and Recovery Act,  49  U.S.C.
     Section 6901, et seq., or other applicable state or Federal laws, rules,
     or  regulations adopted pursuant to any of the foregoing or intended  to
     protect  human  health or the environment ("Environmental  Laws").   The
     terms  "hazardous waste" and "hazardous substance" shall  also  include,
     without  limitation, petroleum and petroleum by-products or any fraction
     thereof  and  asbestos.   The representations and  warranties  contained
     herein  are  based  on  Grantor's  due diligence  in  investigating  the
     Collateral  for  hazardous wastes and substances.   Grantor  hereby  (a)
     releases  and  waives any future claims against Lender for indemnity  or
     contribution  in the event Grantor becomes liable for cleanup  or  other
     costs under any Environmental Laws, and (b) agrees to indemnify and hold
     harmless Lender against any and all claims and losses resulting  from  a
     breach  of  this  provision of this Agreement,  or  as  a  result  of  a
     violation of any Environmental Laws.  This obligation to indemnify shall
     survive  the  payment of the Indebtedness and the satisfaction  of  this
     Agreement.

     Maintenance  of Casualty Insurance.  Grantor shall procure and  maintain
     all  risks  insurance,  including without  limitation  fire,  theft  and
     liability  coverage  together with such other insurance  as  Lender  may
     require with respect to the Collateral, in form, amounts, coverages  and
     basis  reasonably  acceptable to Lender  and  issued  by  a  company  or
     companies  reasonably acceptable to Lender.  Grantor,  upon  request  of
     Lender,  will  deliver  to  Lender from time to  time  the  policies  or
     certificates  of  insurance in form satisfactory  to  Lender,  including
     stipulations that coverages will not be cancelled or diminished  without
     at least ten (10) days' prior written notice to Lender and not including
     any  disclaimer of the insurer's liability for failure to  give  such  a
     notice.   Each  insurance  policy  also  shall  include  an  endorsement
     providing that coverage in favor of Lender will not be impaired  in  any
     way by any act, omission or default of Grantor or any other person.   In
     connection with all policies covering assets in which Lender holds or is
     offered a security interest, Grantor will provide Lender with such  loss
     payable or other endorsements as Lender may require.  If Grantor at  any
     time  fails  to obtain or maintain any insurance as required under  this
     Agreement,  Lender  may  (but shall not be  obligated  to)  obtain  such
     insurance  as  Lender  deems appropriate, including  if  it  so  chooses
     "single interest insurance," which will cover only Lender's interest  in
     the Collateral.

     Application of Insurance Proceeds.  Grantor shall promptly notify Lender
     of  any loss or damage to the Collateral.  Lender may make proof of loss
     if Grantor falls to do so within fifteen (15) days of the casualty.  All
     proceeds  of any insurance on the Collateral, including accrued proceeds
     thereon,  shall be held by Lender as part of the Collateral.  If  Lender
     consents   to  repair  or  replacement  of  the  damaged  or   destroyed
     Collateral, Lender shall, upon satisfactory proof of expenditure, pay or
     reimburse Grantor from the proceeds for the reasonable cost of repair or
     restoration. If Lender does not consent to repair or replacement of  the
     Collateral,  Lender shall retain a sufficient amount of the proceeds  to
     pay  all of the Indebtedness, and shall pay the balance to Grantor.  Any
     proceeds which have not been disbursed within six (6) months after their
     receipt and which Grantor has not committed to the repair or restoration
     of the Collateral shall be used to prepay the Indebtedness.

     Insurance Reserves.  Lender may require Grantor to maintain with  Lender
     reserves  for  payment of insurance premiums, which  reserves  shall  be
     created by monthly payments from Grantor of a sum estimated by Lender to
     be  sufficient to produce, at least fifteen (15) days before the premium
     due  date, amounts at least equal to the insurance premiums to be  paid.
     If  fifteen  (15)  days  before payment is due, the  reserve  funds  are
     insufficient,  Grantor shall upon demand pay any deficiency  to  Lender.
     The reserve funds shall be held by Lender as a general deposit and shall
     constitute  a non-interest-bearing account which Lender may  satisfy  by
     payment of the insurance premiums required to be paid by Grantor as they
     become  due.   Lender  does  not hold the reserve  funds  in  trust  for
     Grantor,  and  Lender is not the agent of Grantor  for  payment  of  the
     insurance  premiums required to be paid by Grantor.  The  responsibility
     for the payment of premiums shall remain Grantor's sole responsibility.

     Insurance  Reports.  Grantor, upon request of Lender, shall  furnish  to
     Lender  reports  on  each  existing policy  of  insurance  showing  such
     information  as  Lender may reasonably request including the  following:
     (a)  the  name of the insurer; (b) the risks insured; (c) the amount  of
     the  policy; (d) the property insured; (e) the then current value on the
     basis of which insurance has been obtained and the manner of determining
     that  value;  and (f) the expiration date of the policy.   In  addition,
     Grantor  shall  upon  request by Lender (however  not  more  often  than
     annually)   have  an  independent  appraiser  satisfactory   to   Lender
     determine,  as  applicable, the cash value or replacement  cost  of  the
     Collateral.

GRANTOR'S  RIGHT  TO POSSESSION AND TO COLLECT ACCOUNTS.  Until  default  and
except as otherwise provided below with respect to accounts and above in  the
paragraph  titled  "Transactions  Involving  Collateral",  Grantor  may  have
possession  of the tangible personal property and beneficial use of  all  the
Collateral  and  may use it in any lawful manner not inconsistent  with  this
Agreement  or  the  Related  Documents,  provided  that  Grantor's  right  to
possession  and  beneficial  use  shall not apply  to  any  Collateral  where
                                       47
<PAGE>
possession of the Collateral by Lender is required by law to perfect Lender's
security  interest in such Collateral.  Until otherwise notified  by  Lender,
Grantor  may  collect any of the Collateral consisting of accounts.   At  any
time  and  even  though no Event of Default exists, Lender may  exercise  its
rights to collect the accounts and to notify account debtors to make payments
directly  to  Lender for application to the Indebtedness.  If Lender  at  any
time  has  possession of any Collateral, whether before or after an Event  of
Default,  Lender  shall be deemed to have exercised reasonable  care  in  the
custody  and preservation of the Collateral if Lender takes such  action  for
that  purpose  as  Grantor  shall request or  as  Lender,  in  Lender's  sole
discretion,  shall deem appropriate under the circumstances, but  failure  to
honor any request by Grantor shall not of itself be deemed to be a failure to
exercise  reasonable care.  Lender shall not be required to  take  any  steps
necessary to preserve any rights in the Collateral against prior parties, nor
to  protect, preserve or maintain any security interest given to  secure  the
Indebtedness.

EXPENDITURES BY LENDER.  If not discharged or paid when due, Lender may  (but
shall  not  be  obligated  to) discharge or pay any amounts  required  to  be
discharged  or  paid  by  Grantor  under this  Agreement,  including  without
limitation  all  taxes,  liens, security interests, encumbrances,  and  other
claims, at any time levied or placed on the Collateral.  Lender also may (but
shall  not  be  obligated  to) pay all costs for  insuring,  maintaining  and
preserving the Collateral.  All such expenditures incurred or paid by  Lender
for  such purposes will then bear interest at the rate charged under the Note
from the date incurred or paid by Lender to the date of repayment by Grantor.
All  such  expenses shall become a part of the Indebtedness and, at  Lender's
option,  will  (a) be payable on demand, (b) be added to the balance  of  the
Note and be apportioned among and be payable with any installment payments to
become  due during either (i) the term of any applicable insurance policy  or
(ii)  the remaining term of the Note, or (c) be treated as a balloon  payment
which  will  be due and payable at the Note's maturity.  This Agreement  also
will secure payment of these amounts.  Such right shall be in addition to all
other rights and remedies to which Lender may be entitled upon the occurrence
of an Event of Default.

EVENTS OF DEFAULT.  Each of the following shall constitute an Event of
Default under this Agreement:

     Default  on  Indebtedness.  Failure of Grantor to make any payment  when
     due on the Indebtedness.

     Other  Defaults.  Failure of Grantor to comply with or  to  perform  any
     other  term,  obligation,  covenant  or  condition  contained  in   this
     Agreement  or in any of the Related Documents or in any other  agreement
     between Lender and Grantor.

     Insolvency.  The dissolution or termination of Grantor's existence as  a
     going business, the insolvency of Grantor, the appointment of a receiver
     for  any  part of Grantor's property, any assignment for the benefit  of
     creditors,  any  type  of creditor workout, or the commencement  of  any
     proceeding  under  any  bankruptcy or  insolvency  laws  by  or  against
     Grantor.

     Creditor  or  Forfeiture Proceedings.  Commencement  of  foreclosure  or
     forfeiture  proceedings,  whether  by  judicial  proceeding,  self-help,
     repossession or any other method, by any creditor of Grantor or  by  any
     governmental  agency  against the Collateral  or  any  other  collateral
     securing  the  Indebtedness.  This includes  a  garnishment  of  any  of
     Grantor's deposit accounts with Lender.  However, this Event of  Default
     shall  not apply if there is a good faith dispute by Grantor as  to  the
     validity  or  reasonableness of the claim which  is  the  basis  of  the
     creditor  or  forfeiture proceeding and if Grantor gives Lender  written
     notice of the creditor or forfeiture proceeding and deposits with Lender
     monies or a surety bond for the creditor or forfeiture proceeding, in an
     amount  determined  by  Lender,  in its sole  discretion,  as  being  an
     adequate reserve or bond for the dispute.

     Events  Affecting  Guarantor.  Any of the preceding events  occurs  with
     respect  to  any Guarantor of any of the Indebtedness or such  Guarantor
     dies or becomes incompetent.  Lender, at its option, may, but shall  not
     be  required to, permit the Guarantor's estate to assume unconditionally
     the  obligations arising under the guaranty in a manner satisfactory  to
     Lender, and, in doing so, cure the Event of Default.

     Insecurity.  Lender, in good faith, deems itself insecure.

RIGHTS AND REMEDIES ON DEFAULT.  If an Event of Default occurs under this
Agreement, at any time thereafter, Lender shall have all the rights of a
secured party under the Oregon Uniform Commercial Code.  In addition and
without limitation, Lender may exercise any one or more of the following
rights and remedies:

     Accelerate  Indebtedness.  Lender may declare the  entire  Indebtedness,
     including any prepayment penalty which Grantor would be required to pay,
     immediately due and payable, without notice.

     Assemble  Collateral.  Lender may require Grantor to deliver  to  Lender
     all  or  any  portion of the Collateral and any and all certificates  of
     title  and  other  documents  relating to the  Collateral.   Lender  may
     require  Grantor  to assemble the Collateral and make  it  available  to
     Lender  at  a place to be designated by Lender.  Lender also shall  have
     full  power to enter upon the property of Grantor to take possession  of
     and  remove the Collateral.  If the Collateral contains other goods  not
                                       48
<PAGE>
     covered  by  this Agreement at the time of repossession, Grantor  agrees
     Lender  may take such other goods, provided that Lender makes reasonable
     efforts to return them to Grantor after repossession.

     Sell  the  Collateral.   Lender shall have full power  to  sell,  lease,
     transfer,  or otherwise deal with the Collateral or proceeds thereof  in
     its  own  name  or that of Grantor.  Lender may sell the  Collateral  at
     public  auction  or  private sale.  Unless the Collateral  threatens  to
     decline  speedily  in  value  or is of a  type  customarily  sold  on  a
     recognized  market, Lender will give Grantor reasonable  notice  of  the
     time  after which any private sale or any other intended disposition  of
     the  Collateral is to be made unless Grantor has signed, after an  Event
     of  Default occurs, a statement renouncing or modifying Grantor's  right
     to notification of sale.  The requirements of reasonable notice shall be
     met  if  such notice is given at least ten (10) days before the time  of
     the  sale  or disposition.  All expenses relating to the disposition  of
     the  Collateral, including without limitation the expenses of  retaking,
     holding, insuring, preparing for sale and selling the Collateral,  shall
     become a part of the Indebtedness secured by this Agreement and shall be
     payable  on  demand,  with  interest at  the  Note  rate  from  date  of
     expenditure until repaid.

     Appoint  Receiver.   To the extent permitted by applicable  law,  Lender
     shall  have  the following rights and remedies regarding the appointment
     of  a receiver: (a) Lender may have a receiver appointed as a matter  of
     right,  (b)  the  receiver may be an employee of Lender  and  may  serve
     without  bond, and (c) all fees of the receiver and his or her  attorney
     shall become pad of the Indebtedness secured by this Agreement and shall
     be  payable  on  demand, with interest at the Note  rate  from  date  of
     expenditure until repaid.

     Collect  Revenues, Apply Accounts.  Lender, either itself or  through  a
     receiver, may collect the payments, rents, income, and revenues from the
     Collateral.   Lender  may  at any time in its  discretion  transfer  any
     Collateral  into  its own name or that of its nominee  and  receive  the
     payments,  rents, income, and revenues therefrom and hold  the  same  as
     security for the Indebtedness or apply it to payment of the Indebtedness
     in  such  order of preference as Lender may determine.  Insofar  as  the
     Collateral   consists   of  accounts,  general  intangibles,   insurance
     policies,  instruments,  chattel paper, choses  in  action,  or  similar
     property,  Lender may demand, collect, receipt for, settle,  compromise,
     adjust,  sue for, foreclose, or realize on the Collateral as Lender  may
     determine, whether or not indebtedness or Collateral is then  due.   For
     these  purposes,  Lender may, on behalf of and in the name  of  Grantor,
     receive,  open  and  dispose of mail addressed to  Grantor;  change  any
     address  to  which mail and payments are to be sent; and endorse  notes,
     checks, drafts, money orders, documents of title, instruments and  items
     pertaining  to  payment, shipment, or storage  of  any  Collateral.   To
     facilitate collection, Lender may notify account debtors and obligors on
     any Collateral to make payments directly to Lender.

     Obtain  Deficiency.   If  Lender chooses to  sell  any  or  all  of  the
     Collateral,  Lender  may  obtain  a judgment  against  Grantor  for  any
     deficiency remaining on the Indebtedness due to Lender after application
     of all amounts received from the exercise of the rights provided in this
     Agreement.   Grantor  shall  be liable for  a  deficiency  even  if  the
     transaction  described  in this subsection is  a  sale  of  accounts  or
     chattel paper.

     Other  Rights  and  Remedies.  Lender shall  have  all  the  rights  and
     remedies  of  a  secured creditor under the provisions  of  the  Uniform
     Commercial  Code,  as may be amended from time to  time.   In  addition,
     Lender  shall have and may exercise any or all other rights and remedies
     it may have available at law, in equity, or otherwise.

     Cumulative  Remedies.   All  of Lender's rights  and  remedies,  whether
     evidenced  by  this Agreement or the Related Documents or by  any  other
     writing,  shall  be  cumulative  and  may  be  exercised  singularly  or
     concurrently.  Election by Lender to pursue any remedy shall not exclude
     pursuit of any other remedy, and an election to make expenditures or  to
     take  action  to perform an obligation of Grantor under this  Agreement,
     after  Grantor's failure to perform, shall not affect Lender's right  to
     declare a default and to exercise its remedies.

MISCELLANEOUS PROVISIONS.  The following miscellaneous provisions are a part
of this Agreement:

     Amendments.   This  Agreement,  together  with  any  Related  Documents,
     constitutes the entire understanding and agreement of the parties as  to
     the  matters set forth in this Agreement.  No alteration of or amendment
     to  this Agreement shall be effective unless given in writing and signed
     by  the party or parties sought to be charged or bound by the alteration
     or amendment.

     Applicable  Law.   This  Agreement has  been  delivered  to  Lender  and
     accepted  by  Lender  in the State of Oregon.  If there  is  a  lawsuit,
     Grantor  agrees  upon Lender's request to submit to the jurisdiction  of
     the  courts  of  Multnomah  County, State of  Oregon.   Subject  to  the
     provisions  on  arbitration, this Agreement shall  be  governed  by  and
     construed in accordance with the laws of the State of Oregon.
                                         49
<PAGE>
     Attorneys'  Fees; Expenses.  Grantor agrees to pay upon  demand  all  of
     Lender's  costs  and expenses, including attorneys'  fees  and  Lender's
     legal  expenses,  incurred in connection with the  enforcement  of  this
     Agreement.   Lender may pay someone else to help enforce this Agreement,
     and Grantor shall pay the costs and expenses of such enforcement.  Costs
     and expenses include Lender's attorneys' fees and legal expenses whether
     or  not there is a lawsuit, including attorneys' fees and legal expenses
     for  bankruptcy proceedings (and including efforts to modify  or  vacate
     any  automatic  stay or injunction), appeals, and any anticipated  post-
     judgment  collection services.  Grantor also shall pay all  court  costs
     and such additional fees as may be directed by the court.

     Caption   Headings.   Caption  headings  in  this  Agreement   are   for
     convenience purposes only and are not to be used to interpret or  define
     the provisions of this Agreement.

     Multiple Parties; Corporate Authority.  All obligations of Grantor under
     this Agreement shall be joint and several, and all references to Grantor
     shall  mean each and every Grantor.  This means that each of the persons
     signing below is responsible for all obligations in this Agreement.

     Notices.  All notices required to be given under this Agreement shall be
     given in writing and shall be effective when actually delivered or  when
     deposited with a nationally recognized overnight courier or deposited in
     the  United States mail, first class, postage prepaid, addressed to  the
     party to whom the notice is to be given at the address shown above.  Any
     party  may change its address for notices under this Agreement by giving
     formal  written notice to the other parties, specifying that the purpose
     of the notice is to change the party's address.  To the extent permitted
     by  applicable  law, if there is more than one Grantor,  notice  to  any
     Grantor  will  constitute notice to all Grantors.  For notice  purposes,
     Grantor agrees to keep Lender informed at all times of Grantor's current
     address(es).

     Power  of  Attorney.  Grantor hereby appoints Lender  as  its  true  and
     lawful attorney-in-fact, irrevocably, with full power of substitution to
     do the following:  (a) to demand, collect, receive, receipt for, sue and
     recover  all sums of money or other property which may now or  hereafter
     become  due, owing or payable from the Collateral; (b) to execute,  sign
     and endorse any and all claims, instruments, receipts, checks, drafts or
     warrants  issued  in  payment  for the  Collateral;  (c)  to  settle  or
     compromise any and all claims arising under the Collateral, and, in  the
     place  and  stead  of Grantor, to execute and deliver  its  release  and
     settlement for the claim; and (d) to file any claim or claims or to take
     any  action or institute or take part in any proceedings, either in  its
     own  name  or  in  the  name  of Grantor, or  otherwise,  which  in  the
     discretion of Lender may seem to be necessary or advisable.  This  power
     is  given  as  security for the Indebtedness, and the  authority  hereby
     conferred is and shall be irrevocable and shall remain in full force and
     effect until renounced by Lender.

     Preference  Payments.   Any monies Lender pays because  of  an  asserted
     preference  claim in Borrower's bankruptcy will become  a  part  of  the
     Indebtedness  and, at Lender's option, shall be payable by  Borrower  as
     provided above in the "EXPENDITURES BY LENDER" paragraph.

     Severability.  If a court of competent jurisdiction finds any  provision
     of  this  Agreement to be invalid or unenforceable as to any  person  or
     circumstance,  such finding shall not render that provision  invalid  or
     unenforceable  as to any other persons or circumstances.   If  feasible,
     any such offending provision shall be deemed to be modified to be within
     the  limits  of  enforceability or validity; however, if  the  offending
     provision  cannot  be so modified, it shall be stricken  and  all  other
     provisions  of this Agreement in all other respects shall  remain  valid
     and enforceable.

     Successor  Interests.  Subject to the limitations  set  forth  above  on
     transfer  of  the Collateral, this Agreement shall be binding  upon  and
     inure to the benefit of the parties, their successors and assigns.

     Waiver.  Lender shall not be deemed to have waived any rights under this
     Agreement  unless such waiver is given in writing and signed by  Lender.
     No delay or omission on the part of Lender in exercising any right shall
     operate  as  a  waiver of such right or any other right.   A  waiver  by
     Lender  of  a  provision  of  this  Agreement  shall  not  prejudice  or
     constitute  a  waiver  of  Lender's right  otherwise  to  demand  strict
     compliance with that provision or any other provision of this Agreement.
     No  prior waiver by Lender, nor any course of dealing between Lender and
     Grantor, shall constitute a waiver of any of Lender's rights or  of  any
     of  Grantor's  obligations as to any future transactions.  Whenever  the
     consent of Lender is required under this Agreement, the granting of such
     consent  by  Lender  in  any  instance shall not  constitute  continuing
     consent  to subsequent instances where such consent is required  and  in
     all cases such consent may be granted or withheld in the sole discretion
     of Lender.

                                        50                    
<PAGE>
                                      
                               PROMISSORY NOTE


Principal Loan Date Maturity Loan No.   Call CollateralAccount Officer Initials
$1,000,000 09-08-1995                    19     0380   8741855333 21728

Borrower: SYNTHETECH, INC.             Lender:    United States National Bank
                                                    of Oregon     
          1290 INDUSTRIAL WAY                      Mid-Willamette Commercial
                                                    Banking Center
          ALBANY, OR 97321                 PL-7 Oregon Corporate Loan Servicing
                                           555 S. W. Oak
                                           Portland, OR 97204

Principal Amount:   $1,000,000.00  Initial Rate: 9.500%     Date of Note:
                                                            September 8, 1995


PROMISE TO PAY.  SYNTHETECH, INC. ("Borrower") promises to pay to United
States National Bank of Oregon ("Lender"), or order, in lawful money of the
United States of America, on demand, the principal amount of One Million &
00/100 Dollars ($1,000,000.00) or so much as may be outstanding, together
with interest on the unpaid outstanding principal balance of each advance.
Interest shall be calculated from the date of each advance until repayment of
each advance.

PAYMENT.  Borrower will pay this loan immediately upon Lender's demand.  In
addition, Borrower will pay regular monthly payments of all accrued unpaid
interest due as of each payment date, beginning October 5, 1995, with all
subsequent interest payments to be due on the same day of each month after
that.  Interest on this Note is computed on a 365/360 simple interest basis;
that is, by applying the ratio of the annual interest rate over a year of 360
days, multiplied by the outstanding principal balance, multiplied by the
actual number of days the principal balance is outstanding.  Borrower will
pay Lender at Lender's address shown above or at such other place as Lender
may designate in writing.  Unless otherwise agreed or required by applicable
law, payments will be applied first to accrued unpaid interest, then to
principal, and any remaining amount to any unpaid collection costs and late
charges.

VARIABLE INTEREST RATE.  The interest rate on this Note is subject to change
from time to time based on changes in an index which is the Lender's Prime
Rate.  This is the rate of interest which Lender from time to time
establishes as its Prime Rate and is not, for example, the lowest rate of
interest which Lender collects from any borrower or class of borrowers (the
"Index').  The interest rate shall be adjusted without notice effective on
the day Bank's prime rate changes.  Lender will tell Borrower the current
Index rate upon Borrower's request.  Borrower understands that Lender may
make loans based on other rates as well.  The interest rate change will not
occur more often than each Day.  The Index currently is 8.750% per annum.
The interest rate to be applied to the unpaid principal balance of this Note
will be at a rate of 0.760 percentage points over the Index, resulting in an
initial rate of 9.500% per annum.

PREPAYMENT.  Borrower agrees that all loan fees and other prepaid finance
charges are earned fully as of the date of the loan and will not be subject
to refund upon early payment (whether voluntary or as a result of default),
except as otherwise required by law.  Except for the foregoing, Borrower may
pay without penalty all or a portion of the amount owed earlier than it is
due.  Early payments will not, unless agreed to by Lender in writing, relieve
Borrower of Borrower's obligation to continue to make payments of accrued
unpaid interest.  Rather, they will reduce the principal balance due.

DEFAULT.  Borrower will be in default if any of the following happens: (a)
Borrower falls to make any payment when due. (b) Borrower breaks any promise
Borrower has made to Lender, or Borrower fails to perform promptly at the
time and strictly in the manner provided in this Note or any agreement
related to this Note, or in any other agreement or loan Borrower has with
Lender. (c) Any representation or statement made or furnished to Lender by
Borrower or on Borrower's behalf is false or misleading in any material
respect. (d) Borrower becomes insolvent, a receiver is appointed for any part
of Borrower's property, Borrower makes an assignment for the benefit of
creditors, or any proceeding is commenced either by Borrower or against
Borrower under any bankruptcy or insolvency laws. (e) Any creditor tries to
take any of Borrower's property on or in which Lender has a lien or security
interest.  This includes a garnishment of any of Borrower's accounts with
Lender. (f) Any of the events described in this default section occurs with
respect to any guarantor of this Note. (g) Lender in good faith deems itself
insecure.

If any default, other than a default in payment, is curable and if Borrower
has not been given a notice of a breach of the same provision of this Note
within the preceding twelve (12) months, it may be cured (and no event of
default will have occurred) if Borrower, after receiving written notice from
Lender demanding cure of such default: (a) cures the default within fifteen
(15) days; or (b) if the cure requires more than fifteen (15) days,
immediately initiates steps which Lender deems in Lender's sole discretion to
be sufficient to cure the default and thereafter continues and completes all
                                    51
<PAGE>
reasonable and necessary steps sufficient to produce compliance as soon as
reasonably practical.

LENDER'S RIGHTS.  Upon default, Lender may declare the entire unpaid
principal balance on this Note and all accrued unpaid interest immediately
due, without notice, and then Borrower will pay that amount.  Upon default,
including failure to pay upon final maturity, Lender, at its option, may
also, if permitted under applicable law, do one or both of the following: (a)
increase the variable interest rate on this Note to 5.750 percentage points
over the Index, and (b) add any unpaid accrued interest to principal and such
sum will bear interest therefrom until paid at the rate provided in this Note
(including any increased rate).  The interest rate will not exceed the
maximum rate permitted by applicable law.  Lender may hire or pay someone
else to help collect this Note if Borrower does not pay.  Borrower also will
pay Lender that amount.  This includes, subject to any limits under
applicable law, Lender's attorneys' fees and Lender's legal expenses whether
or not there is a lawsuit, including attorneys' fees and legal expenses for
bankruptcy proceedings (including efforts to modify or vacate any automatic
stay or injunction), appeals, and any anticipated post-judgment collection
services.  If not prohibited by applicable law, Borrower also will pay any
court costs, in addition to all other sums provided by law.  This Note has
been delivered to Lender and accepted by Lender in the State of Oregon.  If
there is a lawsuit, Borrower agrees upon Lender's request to submit to the
jurisdiction of the courts of Multnomah County, the State of Oregon.  Subject
to the provisions on arbitration, this Note shall be governed by and
construed in accordance with the laws of the State of Oregon.

RIGHT OF SETOFF.  Borrower grants to Lender a contractual possessory security
interest in, and hereby assigns, convoys, delivers, pledges, and transfers to
Lender all Borrower's right, title and interest in and to, Borrower's
accounts with Lender (whether checking, savings, or some other account),
including without limitation all accounts held jointly with someone else and
all accounts Borrower may open in the future, excluding however all IRA,
Keogh, and trust accounts.  Borrower authorizes Lender, to the extent
permitted by applicable law, to charge or setoff all sums owing on this Note
against any and all such accounts.

LINE OF CREDIT.  This Note evidences a revolving line of credit.  Advances
under this Note, as well as directions for payment from Borrower's accounts,
may be requested orally or in writing by Borrower or by an authorized person.
Lender may, but need not, require that all oral requests be confirmed in
writing.  Borrower agrees to be liable for all sums either: (a) advanced in
accordance with the instructions of an authorized person or (b) credited to
any of Borrower's accounts with Lender, regardless of the fact that persons
other than those authorized to borrow have authority to draw against the
accounts.  The unpaid principal balance owing on this Note at any time may be
evidenced by endorsements on this Note or by Lender's internal records,
including daily computer print-outs.  Lender will have no obligation to
advance funds under this Note if: (a) Borrower or any guarantor is in default
under the terms of this Note or any agreement that Borrower or any guarantor
has with Lender, including any agreement made in connection with the signing
of this Note; (b) Borrower or any guarantor ceases doing business or is
insolvent; (c) any guarantor seeks, claims or otherwise attempts to limit,
modify or revoke such guarantor's guarantee of this Note or any other loan
with Lender; (d) Borrower has applied funds provided pursuant to this Note
for purposes other than those authorized by Lender; or (e) Lender in good
faith deems itself insecure under this Note or any other agreement between
Lender and Borrower.

ARBITRATION.  Lender and Borrower agree that all disputes, claims and
controversies between them, whether individual, joint, or class in nature,
arising from this Note or otherwise, including without limitation contract
and tort disputes, shall be arbitrated pursuant to the Rules of the American
Arbitration Association, upon request of either party.  No act to take or
dispose of any collateral securing this Note shall constitute a waiver of
this arbitration agreement or be prohibited by this arbitration agreement.
This includes, without limitation, obtaining injunctive relief or a temporary
restraining order; foreclosing by notice and sale under any deed of trust or
mortgage; obtaining a writ of attachment or imposition of a receiver; or
exercising any rights relating to personal property, including taking or
disposing of such property with or without judicial process pursuant to
Article 9 of the Uniform Commercial Code.  Any disputes, claims, or
controversies concerning the lawfulness or reasonableness of any act, or
exercise of any right, concerning any collateral securing this Note,
including any claim to rescind, reform, or otherwise modify any agreement
relating to the collateral securing this Note, shall also be arbitrated,
provided however that no arbitrator shall have the right or the power to
enjoin or restrain any act of any party.  Judgment upon any award rendered by
any arbitrator may be entered in any court having jurisdiction.  Nothing in
this Note shall preclude any party from seeking equitable relief from a court
of competent jurisdiction.  The statute of limitations, estoppel, waiver,
laches, and similar doctrines which would otherwise be applicable in an
action brought by a party shall be applicable in any arbitration proceeding,
and the commencement of an arbitration proceeding shall be deemed the
commencement of an action for these purposes.  The Federal Arbitration Act
shall apply to the construction, interpretation, and enforcement of this
arbitration provision.

LATE CHARGE.  If a payment is 19 days or more past due, Borrower will be
charged a late charge of 5% of the delinquent payment.

CREDIT ACT - CHECKING ACCOUNT NUMBER 022-0016-224 LOCATED AT THE ALBANY
COMMUNITY BRANCH.  Borrower has requested and been granted Lender's
Commercial Line of Credit Automatic Cash Transfer Service ("Credit ACT").  So
long as this Note is in place, Borrower authorizes Lender to draw from
Borrower's available line of credit and transfer funds automatically to
Borrower's commercial checking account described in the heading of this
paragraph ("Checking Account") in accordance with this section.  So long as
                                   52
<PAGE>
this agreement is in place, Lender agrees to make an automatic cash transfer
from Borrower's line of credit to its Checking Account in increments of
$500.00, to pay checks that would otherwise overdraw Borrower's Checking
Account by $100.00 or more, up to Borrower's available credit limit.  The
amount of each Credit ACT transfer will be an advance under the terms of this
Note.  There is no charge for using Credit ACT.  Borrower agrees to pay
prevailing overdraft or other applicable checking account charges then in
effect if an overdraft may not be paid because an ACT in the required
increment of $500.00 to pay the full amount of the overdraft would exceed
Borrower's credit limit.  If Borrower's credit limit has been exceeded, and
no other ACT privileges are available to Borrower, any check presented for
payment from Checking Account will, at the sole option of Lender, either be
paid, thus overdrawing Checking Account, or dishonored.  Lender may change
the terms of Credit ACT at any time by giving Borrower written notice, sent
to the Borrower's address as shown in Lender's records, prior to the
effective date of the change.

Lender reserves the right to discontinue this service upon giving written
notice to the Borrower, at Borrower's address shown in Lender's records,
under the following circumstances: (1) Lender reasonably believes that
Borrower will be unable to fulfill its repayment obligations because of a
material adverse change in Borrower's financial circumstances. (2) Borrower
fails to promptly provide financial information that Lender has requested.
(3) Borrower is in default of a material provision of any promissory note or
loan agreement with Lender.

If Lender discontinues further Credit ACT services due to any of these
circumstances, Lender will mail Borrower written notice of the
discontinuation and the reasons therefor.  After such notice is given,
Borrower must request in writing that its Credit ACT be reinstated.  Before
Credit ACT privileges are reinstated, Lender may ask Borrower to provide new
information, at Borrower's expense.  If Borrower shows Lender that the
circumstances that caused cancellation of Credit ACT services have ceased to
exist, Credit ACT will be reinstated at Lender's sole option and discretion
upon written notice to Borrower.

PERIODIC REVIEW.  Lender will review the loan periodically.  At the time of
the review, Borrower will furnish Lender with any additional information
regarding Borrower's financial condition and business operations that Lender
requests.  This information may include, but is not limited to, financial
statements, tax returns, lists of assets and liabilities, agings of
receivables and payables, inventory schedules, budgets and forecasts.  If
upon review, Lender, in its sole discretion, determines that there has been a
material adverse change in Borrower's financial condition, Borrower will be
in default.  Upon default, Lender shall have all rights specified herein.

DEMAND NOTE.  BORROWER ACKNOWLEDGES AND AGREES THAT (A) THIS NOTE IS A DEMAND
NOTE, AND LENDER IS ENTITLED TO DEMAND BORROWER'S IMMEDIATE PAYMENT IN FULL
OF ALL AMOUNTS OWING HEREUNDER, (B) NEITHER ANYTHING TO THE CONTRARY
CONTAINED HEREIN OR IN ANY OTHER LOAN DOCUMENTS (INCLUDING BUT NOT LIMITED
TO, PROVISIONS RELATING TO DEFAULTS, RIGHTS OF CURE, DEFAULT RATE OF
INTEREST, INSTALLMENT PAYMENTS, LATE CHARGES, PERIODIC REVIEW OF BORROWER'S
FINANCIAL CONDITION, AND COVENANTS) NOR ANY ACT OF LENDER PURSUANT TO ANY
SUCH PROVISIONS SHALL LIMIT OR IMPAIR LENDER'S RIGHT OR ABILITY TO REQUIRE
BORROWER'S PAYMENT IN FULL OF ALL AMOUNTS OWING HEREUNDER IMMEDIATELY UPON
LENDER'S DEMAND, AND (C) UPON LENDER MAKING ANY SUCH DEMAND, LENDER SHALL
HAVE NO OBLIGATION TO MAKE ANY ADVANCE UNDER THIS NOTE OR UNDER THE LOAN
DOCUMENTS.

GENERAL PROVISIONS.  This Note is payable on demand.  The inclusion of
specific default provisions or rights of Lender shall not preclude Lender's
right to declare payment of this Note on its demand.  Lender may delay or
forgo enforcing any of its rights or remedies under this Note without losing
them.  Borrower and any other person who signs, guarantees or endorses this
Note, to the extent allowed by law, waive presentment, demand for payment,
protest and notice of dishonor.  Upon any change in the terms of this Note,
and unless otherwise expressly stated in writing, no party who signs this
Note, whether as maker, guarantor, accommodation maker or endorser, shall be
released from liability.  All such parties agree that Lender may re-new or
extend (repeatedly and for any length of time) this loan, or release any
party or guarantor or collateral; or impair, fail to realize upon or perfect
Lender's security interest in the collateral; and take any other action
deemed necessary by Lender without the consent of or notice to anyone.  All
such parties also agree that Lender may modify this loan without the consent
of or notice to anyone other than the party with whom the modification is
made.

UNDER OREGON LAW, MOST AGREEMENTS, PROMISES AND COMMITMENTS MADE BY US
(LENDER) AFTER OCTOBER 3, 1989 CONCERNING LOANS AND OTHER CREDIT EXTENSIONS
WHICH ARE NOT FOR PERSONAL, FAMILY OR HOUSEHOLD PURPOSES OR SECURED SOLELY BY
THE BORROWER'S RESIDENCE MUST BE IN WRITING, EXPRESS CONSIDERATION AND BE
SIGNED BY US TO BE ENFORCEABLE.

PRIOR TO SIGNING THIS NOTE, BORROWER READ AND UNDERSTOOD ALL THE PROVISIONS
OF THIS NOTE, INCLUDING THE VARIABLE INTEREST RATE PROVISIONS.  BORROWER
AGREES TO THE TERMS OF THE NOTE AND ACKNOWLEDGES RECEIPT OF A COMPLETED COPY
OF THE NOTE.
                                     53
<PAGE>
BORROWER:

SYNTHETECH, INC.

     \s\ Charles B. Williams, VP                       \s\ Philip Knutson, VP
X                                       X
     Authorized Officer                           Authorized Officer

LENDER:

United States National Bank of Oregon


By
     Authorized Officer
                                   54

<PAGE>                                                                        
                                                                   Exhibit 23
                                                                to Form 10KSB
                                      
                                      
                                      
                  CONSENT OF INDEPENDENT PUBLIC ACCOUNTANTS
                                      
                                      
As independent public accountants, we hereby consent to the incorporation of
our report dated May 16, 1996 included in this Form 10-K for the year ended
March 31, 1996, into Synthetech, Inc.'s previously filed Registration
Statement Nos. 33-45913 and 33-64621.



Portland, Oregon,
  June 4, 1996
                                       55

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 5
<LEGEND>
This schedule contains summary financial information extracted from the March
31, 1996 10KSB Balance Sheets, Income Statements, and Cash Flow Statements,
and is qualified in its entirety by reference to such financial statements.
</LEGEND>
       
<S>                                  <C>
<PERIOD-TYPE>                         12-MOS
<FISCAL-YEAR-END>                     MAR-31-1996
<PERIOD-END>                          Mar-31-1996
<CASH>                                5049000
<SECURITIES>                           395000
<RECEIVABLES>                         1355000
<ALLOWANCES>                                0
<INVENTORY>                           1924000
<CURRENT-ASSETS>                      9006000
<PP&E>                                1311000
<DEPRECIATION>                              0
<TOTAL-ASSETS>                       10959000
<CURRENT-LIABILITIES>                  849000
<BONDS>                                     0
<COMMON>                                13000
                       0
                                 0
<OTHER-SE>                           10100000
<TOTAL-LIABILITY-AND-EQUITY>         10959000
<SALES>                               8472000
<TOTAL-REVENUES>                      8472000
<CGS>                                 3685000
<TOTAL-COSTS>                         4735000
<OTHER-EXPENSES>                            0
<LOSS-PROVISION>                            0
<INTEREST-EXPENSE>                          0
<INCOME-PRETAX>                       4022000
<INCOME-TAX>                          1448000
<INCOME-CONTINUING>                   2574000
<DISCONTINUED>                              0
<EXTRAORDINARY>                             0
<CHANGES>                                   0
<NET-INCOME>                          2574000
<EPS-PRIMARY>                             .19
<EPS-DILUTED>                             .19
        

</TABLE>


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