SYNTHETECH INC
S-3, 1996-07-16
INDUSTRIAL ORGANIC CHEMICALS
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<PAGE>
As filed with the Securities and Exchange Commission on July 16, 1996
                                               Registration No. 333

                 SECURITIES AND EXCHANGE COMMISSION
                       Washington, D.C. 20549 FORM S-3
                    REGISTRATION STATEMENT UNDER THE
                     SECURITIES ACT OF 1933
                     
                          SYNTHETECH, INC.
(Exact name of Registrant as specified in its charter)
      Oregon                                 84-0845771
     (State of                            (I.R.S. Employer
  Incorporation)                           Identification
                                             No.)
                    1290 Industrial Way
                  Albany, Oregon  97321
                     (541) 967-6575
    (Address, Including Zip Code, and Telephone Number,
  Including Area Code, of Registrant's Principal Executive
                          Offices)
                     M. Sreenivasan
           President and Chief Executive Officer
                      SYNTHETECH, INC.
                    1290 Industrial Way
                  Albany, Oregon  97321
                     (541) 967-6575
 (Name, Address, Including Zip Code, and Telephone
         Number, Including Area Code, of Agent for Service)
                         Copies to:
            Cynthia Clarfield Hess,       David R. Clarke,
            Esq.                          Esq.
            Sehar S. Ahmad, Esq.          VENTURE COUNSEL,
            PERKINS COIE                  P.C.
            1211 S.W. Fifth Avenue,       Suite 250
            Suite 1500                    1230 S.W. First
            Portland, OR 97204            Avenue
            (503) 727-2000                Portland, Oregon
                                          97204
                                          (503) 225-9000
    Approximate date of commencement of proposed sale to the
                             public:
     As soon as practicable after the effective date of this
                     Registration Statement.
                     
    If any securities being registered on this form are being
offered pursuant to dividend or interest reinvestment plans,
please check the following box.
     If any of the securities being registered on this form are
to be offered on a delayed or continuous basis pursuant to Rule
415 under the Securities Act of 1933, other than securities
offered only in connection with dividend or interest
reinvestment plans, check the following box.  X

                   CALCULATION OF REGISTRATION FEE
   Title of Each  Amount to   Proposed   Proposed
                    Amount
     Class           be       Maximum     Maximum       of
of Securities to  Registered   Offering   Aggregate Registration
 be Registered                Price Per   Offering   
                              Share(1)    Price(1)      Fee
Common Stock,      850,000     $7.50    $6,375,000 $2,198.28
$.001 par value                                        
(1)   Estimated solely for the purpose of calculating the
 registration fee under Rule 457.  The offering price has been
 estimated and the registration fee has been computed pursuant
 to Rule 457(c).  The price per share is estimated to be $7.50
 based on the average of the bid and asked price quoted for the
 Common Stock in the over-the-counter market on July 11, 1996
 as reported on the Nasdaq Small Cap Market.

     The Registrant hereby amends this Registration Statement
on such  date  or  dates as may be necessary to delay its
effective date  until  the Registrant shall file a further
amendment  which specifically  states  that       this
Registration  Statement   shall thereafter  become effective in accordance 
with Section  8(a)of the   Securities  Act  of  1933,  as  amended,  or   
untilthis Registration Statement shall become effective on such date
as the Commission, acting pursuant to said Section 8(a), may
determine. 
<PAGE>
                           850,000 Shares

                          SYNTHETECH, INC.

                            Common Stock


This  Prospectus covers up to 850,000 shares of  common  stock,
$.001  par value per share (the "Shares") of Synthetech,  Inc.,
an  Oregon  corporation (the "Company"), being sold by  certain
shareholders of the Company (the "Selling Shareholders").   See
"Selling Shareholders."  The Company will not receive any  part
of  the  proceeds from the sale of the Shares in this  offering
(the "Offering").

The  Common Stock is currently traded over-the-counter  on  the
Nasdaq  Small Cap Market under the symbol "NZYM."   Application
has been made to have the Common Stock approved for trading  on
the  Nasdaq National Market.  On July 11, 1996, the average  of
the  bid  and  asked price for the Common Stock was  $7.50  per
share.


See "Risk Factors" beginning on page 3 of this Prospectus for a
discussion  of  certain factors that should  be  considered  by
prospective purchasers of the Shares.


      THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED
         BY THE SECURITIES AND EXCHANGE COMMISSION NOR HAS THE
           COMMISSION PASSED UPON THE ACCURACY OR ADEQUACY
             OF THIS PROSPECTUS.  ANY REPRESENTATION TO
                 THE CONTRARY IS A CRIMINAL OFFENSE.
                                  
<TABLE>
<CAPTION>
<S>                  <C>          <C>           <C>       <C>
                                
                       Price to  Underwriting  Proceeds    Proceeds to
                      Public(1)  Discounts        to         Selling
                                    and         Company   Shareholders(2)
                                 Commissions(1)
Per Share               $7.50       $--           $0          $7.50
Total                 $6,375,00     $--           $0        $6,375,000
                         
</TABLE>

(1)The Selling Shareholders may sell the Shares to or through dealers
   at market prices prevailing at the time of sale, at prices related
   to  such  prevailing market prices or at negotiated  prices.   The
   above  computations are based on the average of the bid and  asked
   price  of  the  Common  Stock as of  July  11,  1996  and  do  not
   necessarily  reflect the prices of shares to  the  public  on  the
   dates the transactions are actually effected.
   
(2)Expenses of this Offering, estimated at $45,000, are payable by
   the Company.
   
   
   
            The date of this Prospectus is ________, 1996
<PAGE>
                        AVAILABLE INFORMATION

The  Company  has  filed a Registration Statement on  Form  S-3  (the
"Registration  Statement")  under the  Securities  Act  of  1933,  as
amended  (the  "Securities Act"), with the  Securities  and  Exchange
Commission (the "Commission"), Washington, D.C., with respect to  the
Shares  offered hereby.  The Prospectus does not contain all  of  the
information set forth in the Registration Statement and the  exhibits
thereto.  For further information with respect to the Company and the
Shares,  reference  is  made to the Registration  Statement  and  the
exhibits  thereto.   Statements made in this  Prospectus  as  to  the
contents  of  any  contract or other document  referred  to  are  not
necessarily complete, and in each instance reference is made  to  the
copy  of such contract or other document filed as an exhibit  to  the
Registration  Statement, each such statement being qualified  in  all
respects by such reference.

The   Registration  Statement  is  available  for   review   at   the
Commission's  offices  in  Washington,  D.C.   All  or  part  of  the
Registration Statement may be inspected and copied, upon  payment  of
the   prescribed  fees,  at  the  Public  Reference  Section  of  the
Commission, 450 Fifth Street N.W., Judiciary Plaza, Washington,  D.C.
20549-1004.

In addition, the Company is subject to the informational requirements
of  the  Securities Exchange Act of 1934, as amended  (the  "Exchange
Act"),  and  in accordance therewith files reports, proxy  statements
and  other  information  with the Commission.   Such  reports,  proxy
statements and other information can be inspected and copied at,  and
copies of such material obtained at prescribed rates from, the public
reference  facilities  maintained by  the  Commission  at  450  Fifth
Street, N.W., Judiciary Plaza, Washington, D.C. 20549-1004 and at the
Commission's regional offices located at 7 World Trade Center,  Suite
1300,  New York, New York 10048 and Citicorp Center, 500 West Madison
Street, Suite 1400, Chicago, Illinois 60661-2511.

A  copy  of  the  Company's 1996 Annual Report  containing  financial
statements  audited  by the Company's independent public  accountants
was  first mailed to the Shareholders on June 19, 1996.  The  Company
intends to continue to furnish Annual Reports to its Shareholders.

           INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

The  following  documents filed with the Commission pursuant  to  the
Exchange Act are incorporated in this Prospectus by reference:

     1.   The  Company's Annual Report on Form 10-KSB  for  the  year
          ended   March  31,  1996,  including  financial  statements
          incorporated by reference.

     2.   The description of the Company's Common Stock contained  in
          the  Registration  Statement on Form  8-A  filed  with  the
          Commission on November 8, 1984 under Section 12(g)  of  the
          Exchange Act.

All documents filed by the Company pursuant to Sections 13(a), 13(c),
14 or 15(d) of the Exchange Act after the date of this Prospectus and
prior  to  the  termination of this Offering shall be  deemed  to  be
incorporated by reference in this Prospectus and to be a part  hereof
from  the date of filing of such documents (such documents,  and  the
documents  enumerated  above,  being  hereinafter  referred   to   as
"Incorporated Documents").

Any  statement contained in an Incorporated Document shall be  deemed
to  be modified or superseded for purposes of this Prospectus and the
Registration  Statement of which it is a part to the  extent  that  a
statement  contained  herein  or  in  any  other  subsequently  filed
Incorporated  Document  or in an accompanying  prospectus  supplement
modifies  or  supersedes  such  statement.   Any  such  statement  so
modified or superseded shall not be
<PAGE>
deemed, except as so modified or superseded, to constitute a part of
this Prospectus or such Registration Statement.

The Company will provide without charge to each person to whom a copy
of this Prospectus has been delivered, on the written or oral request
of  any  such  person,  a  copy of any or  all  of  the  Incorporated
Documents,  other  than  exhibits  to  such  documents,  unless  such
exhibits   are   specifically  incorporated  by  reference   therein.
Requests should be directed to Charles B. Williams, Vice President of
Administration  and Finance, Chief Financial Officer,  Secretary  and
Treasurer,  at the Company's principal executive offices, Synthetech,
Inc., 1290 Industrial Way, Albany, Oregon 97321, telephone (541) 967
6575.   The  information relating to the Company  contained  in  this
Prospectus  does not purport to be comprehensive and should  be  read
together   with   the  information  contained  in  the   Incorporated
Documents.

                            RISK FACTORS

Prospective  investors should consider the following  factors,  among
others,  in  making a decision concerning purchase of the  shares  of
Common Stock offered hereby:

Uncertain  Market for Products and Potential Quarterly  Fluctuations.
The  market  for peptide building blocks is driven by the market  for
the  peptide-based drugs into which they are incorporated.  The  drug
development  process is dictated by the marketplace,  drug  companies
and  the regulatory environment.  The Company has no control over the
pace of peptide-based drug development, which drugs get selected  for
clinical  trials,  which drugs are approved  by  the  Food  and  Drug
Administration ("FDA"), and, even if approved, the ultimate potential
of such drugs.  Currently, most of the Company's products are used in
clinical-stage  drugs  which are subject to  a  significant  risk  of
suspension or early cancellation and only a very small percentage  of
which  are ultimately approved for market use.  Due to the wide range
of  drugs under development, sizable fluctuations in orders, and  the
unpredictability of order or reorder cycles for products, the Company
does not have a stable baseload of demand for its products and cannot
estimate  the  potential  market for  its  products.   The  Company's
customers  vary  substantially from year  to  year  and  the  Company
currently  cannot  rely on any one customer as a constant  source  of
revenue.   For the foregoing reasons, the Company has experienced  in
the  past,  and  is  likely to experience in the future,  significant
fluctuations  in its quarterly results.  Due to the small  number  of
approved peptide-based drugs, there can be no assurance that a market
for peptide building blocks will continue to exist.

     Industry  Cost Factors.  The market for peptide building  blocks
is  dependent on the market for pharmaceuticals products.  The levels
of  revenues  and  profitability of pharmaceutical companies  may  be
affected  by  the continuing efforts of governmental and third  party
payors  to contain or reduce the cost of health care through  various
means.    For  example,  in  certain  foreign  markets,  pricing   or
profitability   of  prescription  pharmaceuticals   is   subject   to
government control.  In the United States, there have been,  and  the
Company  expects that there will continue to be, a number of  federal
and  state  proposals to implement similar government  controls.   In
addition,  in  both  the  United  States  and  elsewhere,  sales   of
prescription   pharmaceuticals  are  dependent   in   part   on   the
availability of reimbursement to the consumer from third party payors
such  as government and private insurance plans.  Third party  payors
are  increasingly challenging the prices charged for medical products
and  services.   There  can be no assurance that peptide-based  drugs
will  be  considered cost effective, and that reimbursement  will  be
available or sufficient to allow peptide-based drugs to be sold on  a
profitable   basis.    In  addition,  as  cost   pressures   in   the
pharmaceutical  industry have tightened, the  cancellation  rate  for
drug  development programs has increased.  Because a majority of  the
Company's  revenues  historically have  come  from  peptide  building
blocks used in drug development programs, such cancellations may have
a significant impact on the Company's business.
<PAGE>

     Regulatory  Matters.  The Company is subject  to  a  variety  of
federal, state and local laws, rules and regulations related  to  the
discharge   or  disposal  of  toxic,  volatile  or  other   hazardous
chemicals.   Although the Company believes that it is  in  compliance
with these laws, rules and regulations in all material respects,  and
to  date  has  not been required to take any action  to  correct  any
noncompliance,  the  failure  to  comply  with  present   or   future
regulations  could  result in fines being  imposed  on  the  Company,
suspension  of production or cessation of operations.  Third  parties
may  also have the right to sue to enforce compliance.  Moreover,  it
is   possible  that  increasingly  strict  requirements  imposed   by
environmental laws and enforcement policies thereunder could  require
the  Company to make significant capital expenditures.  The operation
of  a  chemical  manufacturing plant entails  the  inherent  risk  of
environmental  damage  or personal injury  due  to  the  handling  of
potentially  harmful substances, and there can be no  assurance  that
material  costs and liabilities will not be incurred  in  the  future
because of an accident or other event resulting in personal injury or
unauthorized  release  of such substances  to  the  environment.   In
addition, the Company generates hazardous materials and other  wastes
which are disposed at various offsite facilities.  The Company may be
liable,  irrespective of fault, for material cleanup costs  or  other
liabilities incurred at these disposal facilities in the event  of  a
release   of  hazardous  substances  by  such  facilities  into   the
environment.  The Company has obtained environmental risk insurance.

     Potential  Regulation.  The peptide building blocks produced  by
the Company are intermediate ingredients which are then processed  by
the companies to which they are sold, and are therefore currently not
subject to the requirements of the FDA.  The Company's customers  do,
however,  typically impose inspection and quality assurance  programs
on  the  Company.  These programs involve materials handling,  record
keeping  and other requirements.  As many of the Company's  customers
are  requiring  increased processing by the Company of its  products,
the   Company  expects  these  compliance  programs  to  become  more
extensive.  The Company may not be able to comply with the applicable
requirements  or  such requirements may require  the  expenditure  of
significant capital.

     Product   Liability.    Use  of  the   Company's   products   in
pharmaceuticals  and the subsequent testing, marketing  and  sale  of
such  pharmaceuticals involves an inherent risk of product liability.
In  addition,  research  and development  activities  in  amino  acid
technology,  and the production of fine chemicals (including  organic
chemicals) may expose workers engaged in performing duties related to
such  activities to health hazards.  There can be no  assurance  that
claims for product liability will not be asserted against the Company
or  that  the Company would be able to successfully defend any  claim
that  may  be  asserted.   A product liability  claim  could  have  a
material adverse effect on the business and/or financial condition of
the Company.

     Competition.  The Company does not have a significant amount  of
direct    competition    because    peptide-based    pharmaceuticals,
particularly   those  which  utilize  synthetic  amino   acids,   are
relatively  new and the market for peptide building blocks  is  still
very  small.   As  the market continues to grow with multi-ton  order
sizes  becoming  more prevalent, the Company has begun  to  see  more
competition.   Current  competition  in  the  multi-kilo  or  smaller
quantities of natural amino acid based peptide building blocks  comes
primarily  from several European fine chemical companies.   Multi-ton
order  sizes of these natural peptide building blocks have  begun  to
attract   a  wider  group  of  domestic  and  international  chemical
companies.   In  the  area  of synthetic  amino  acid  based  peptide
building  blocks, the Company has competition on a selective  product
basis from fine chemical producers in Europe and Japan.

     Competition also increases for supplying peptide building blocks
for  drug  development programs that reach late clinical  trials  and
move  into  an  approved status as a result of  increased  quantities
typically  required  at  these  stages  and  pharmaceutical   company
requirements  to  have  second sources of  material  available.   The
Company's  competitors have technical, financial, selling  and  other
resources available to them that is significantly greater than  those
available to the Company.
<PAGE>

     Risks  of  Technological Change.  The market for  the  Company's
products  is  characterized  by rapid changes  in  both  product  and
process  technologies.   The Company's future results  of  operations
will  depend  upon  its ability to improve and  market  its  existing
products  and  to successfully develop, manufacture  and  market  new
products.  There can be no assurance that the Company will be able to
continue  to improve and market its existing products or develop  and
market  new  products,  or that technological developments  will  not
cause  the  Company's products or technology to  become  obsolete  or
noncompetitive.

     Manufacturing  Capacity.  The Company currently manufactures  peptide
building  blocks.   As a manufacturer, the Company  will  continually
face risks regarding the availability and costs of raw materials  and
labor, the potential need for additional capital equipment, increased
maintenance  costs,  plant  and equipment  obsolescence  and  quality
control.   Because  the  Company  is  facing  manufacturing  capacity
constraints  in its existing facility, the Company is in the  process
of constructing an additional plant at its Albany, Oregon location to
increase  production  capacity.   There  can  be  no  assurance  that
completion of the new facility will not be subject to delays and that
the  existing  facility will have sufficient  capacity  to  meet  the
demand  for  the Company's products, particularly in the  event  that
several  of  the  peptide-based drugs for which the Company  supplies
peptide    building   blocks   simultaneously   become   commercially
successful.  A disruption in the Company's production or distribution
could  have  a  material  adverse effect on the  Company's  financial
results.

     Uncertain Ability to Manage Growth.  The Company anticipates that  in
order  to  remain  successful in its industry, the  Company  will  be
required  to increase its production and employee base.  The  Company
anticipates  these  increases may place significant  demands  on  the
Company's  management, working capital and financial  and  management
control systems.  The Company may not be able to meet the demands  of
future growth.  Any inadequacies in these areas could have a material
adverse  effect  on the Company's business, financial  condition  and
results of operations.

     Dependence on Key Personnel.  The Company is highly dependent on  the 
principal  members  of its senior management and key  scientific  and
technical  personnel.  The Company's success is also  dependent  upon
its  ability  to attract and retain additional qualified  scientific,
technical  and managerial personnel.  Significant competition  exists
for  such  personnel, and there can be no assurance that the  Company
will retain its key employees or that it will be able to attract  and
retain  such  other highly-qualified personnel as may be required  in
the future.  The Company does not have employment agreements with any
of its personnel or key man life insurance on the lives of any of its
personnel.  The inability of the Company to successfully hire, train,
and  retain qualified personnel could have an adverse effect  on  the
Company.

     Risks of International Business.  Sales to customers outside the
United  States  accounted for approximately 21% of the Company's  net
sales during the year ended March 31, 1996.  The Company expects that
international  sales  will  continue to  account  for  a  significant
percentage  of  net sales.  The Company's business  is  and  will  be
subject  to  the  risks  generally  associated  with  doing  business
internationally,   including  changes  in   demand   resulting   from
fluctuations  in exchange rates, foreign governmental regulation  and
changes  in economic conditions.  These factors, among others,  could
influence the Company's ability to sell its products in international
markets.  In addition, the Company's business is subject to the risks
associated  with  legislation  and regulation  relating  to  imports,
including quotas, duties or taxes and other charges, restrictions and
retaliatory  actions  on  imports to other  countries  in  which  the
Company's products may be sold or manufactured.

     Absence of Dividends.  The Company has not paid any dividends on  its
Common  Stock since its inception and does not anticipate paying  any
dividends  in  the foreseeable future.  Earnings of the  Company,  if
any, are expected to be used to finance the development and expansion
of  the  Company's  business.  Any future decision  with  respect  to
dividends  will depend on future earnings, future capital  needs  and
the Company's operating and financial condition, among other factors.
See "Description of Securities--Common Stock."
<PAGE>
     Volatility of Stock Price.  There has been significant volatility  in
the market price of the Company's common stock.  Between July 1, 1995
and June 30, 1996, the bid price of the Company's common stock ranged
from  $3.22  per  share to $10.75 per share.   The  Common  Stock  is
currently  traded  on the Nasdaq Small Cap Market.   Application  has
been made to have the Common Stock approved for trading on the Nasdaq
National  Market,  which market has experienced,  and  is  likely  to
experience  in the future, significant price and volume  fluctuations
that  could  adversely affect the market price of  the  Common  Stock
without  regard  to the Company's performance.  The Company  believes
factors such as fluctuations in financial results and developments in
its  industry  could contribute to the volatility  of  the  price  of
Common  Stock.  These factors, as well as general economic conditions
such  as recessions or high interest rates, may adversely affect  the
market price of the Common Stock.

     Exercise of Warrants and Options; Potential Adverse Impact of  Shares
Eligible for Future Sales.  As of June 30, 1996, 1,044,260 shares  of
Common  Stock  were  subject to outstanding stock options  under  the
Company's Stock Option Plan at a weighted average exercise  price  of
$3.57  per  share  and 25,000 shares were issuable upon  exercise  of
outstanding  warrants at a weighted average exercise price  of  $1.81
per  share.   While outstanding warrants and options are exercisable,
the holders thereof have the opportunity to profit from a rise in the
market  price  of  the common stock.  The Company may  find  it  more
difficult  to raise additional equity capital while the warrants  and
options  are  outstanding.  At any time when  the  holders  might  be
expected  to  exercise their warrants and options, the Company  would
probably  be able to obtain additional equity capital on  terms  more
favorable  than  those  provided in the warrants  and  options  being
exercised.   Holders of warrants and options do not have any  of  the
rights or privileges of stockholders of the Company prior to exercise
of the warrants and options.

Sales  of  substantial amounts of the Company's common stock  in  the
public  market  by existing shareholders could adversely  affect  the
price  of  the  common stock.  In addition to the 850,000  shares  of
common  stock  offered hereby, 8,417,791 shares are  freely  tradable
under the federal securities laws to the extent they are not held  by
affiliates  of the Company.  At June 30, 1996, 4,222,865 shares  were
eligible  for resale under Rule 144.  In general, under Rule  144  as
currently  in  effect,  any  person  (or  persons  whose  shares  are
aggregated) who has beneficially owned restricted securities  for  at
least two years is entitled to sell, within any three-month period, a
number  of shares that does not exceed the greater of (i) 1%  of  the
then  outstanding shares of the issuer's common stock  and  (ii)  the
average  weekly  trading  volume  during  the  four  calendar   weeks
preceding  such sale, provided that certain public information  about
the  issuer as required by Rule 144 is then available and the  seller
complies  with certain other requirements.  A person who  is  not  an
affiliate,  has  not been an affiliate within three months  prior  to
sale,  and  has beneficially owned the restricted securities  for  at
least  three years is entitled to sell such shares under Rule  144(k)
without regard to any of the limitations described above.
<PAGE>

                        SELLING SHAREHOLDERS
<TABLE>
<CAPTION>
<S>          <C>           <C>              <C>           <C>
                                           Percentage of Outstanding
  Selling        Shares        Shares        Before         After
Shareholders  Beneficially   Registered       Sales         Sales
                 Owned          For
                               Sale
JB Partners   2,000,000     750,000           14.8%         9.3%
Eric D.          50,000      50,000              *            0%
Emanuel
Sheldon          50,000      50,000              *            0%
Kraft
</TABLE>
______________
*Less than 1%.

Pursuant  to a Shareholders Agreement among JB Partners, a  New  York
limited  partnership  ("JB"),  and the  then  current  directors  and
officers  of  the  Company who held shares of  the  Company's  Common
Stock, such shareholders have agreed to vote their shares in favor of
the  election to the Board of Directors of a person nominated by  JB.
Such  agreement  shall  terminate on the  earlier  to  occur  of  the
following:   (i)  JB's ownership of common stock is reduced  to  less
than  500,000  shares,  (ii) the effectiveness  of  the  registration
statement  pursuant to JB's demand registration rights set  forth  in
its  Stock  and  Warrant  Purchase Agreement  with  the  Company,  as
amended,  (iii)  any merger, consolidation or reorganization  of  the
Company in which more than 50% of the voting power of the Company  is
transferred or (iv) March 31, 1998.

                      DESCRIPTION OF SECURITIES
                                  
                                  
Common Stock

The   authorized   capital   stock  of  the   Company   consists   of
100,000,000 shares of common stock, $.001 par value per share.  As of
May   30,  1996,  there  were  13,510,736  shares  of  common   stock
outstanding.  All of the outstanding shares of Common Stock are fully
paid and nonassessable.

Holders of Common Stock are entitled to receive dividends as may from
time  to  time  be declared by the Board of Directors  out  of  funds
legally  available therefor and to one vote per share on all  matters
on  which  the  holders of Common Stock are entitled  to  vote.   The
current policy of the Company is to retain earnings to provide  funds
for  the  operation and expansion of its business.  The  Company  has
never  paid any cash dividends, and the Board of Directors  does  not
anticipate  paying  cash  dividends in the foreseeable  future.   See
"Risk Factors--Absence of Dividends."  Holders of common stock do not
have   any  cumulative  voting  rights  or  conversion,  pre-emptive,
redemption  or  sinking fund rights.  In the event of a  liquidation,
dissolution or winding up of the Company, holders of Common Stock are
entitled  to  share equally and ratably in the Company's  assets,  if
any, remaining after the payment of all liabilities of the Company.

The  holders of Common Stock are entitled to one vote for each  share
held on all matters submitted to the shareholders.
<PAGE>

Indemnification of Directors

Article  7  of  the Company's Articles provides that the  Company  is
required  to indemnify current or former directors of the Company  to
the  fullest extent permitted by the Oregon Business Corporation  Act
(the "Act").

The  Company  has entered into Indemnification Agreements  with  each
current  and  former officer and director documenting  and  detailing
such  indemnification  rights.  The Company  expects  to  enter  into
similar  agreements with future officers and directors.  The  Company
has  obtained  insurance  for the protection  of  its  directors  and
officers  against  any  liability  asserted  against  them  in  their
official  capacities, including coverage under  the  Securities  Act.
The  rights of indemnification under the Articles and the Act are not
exclusive of any other rights of indemnification to which the persons
indemnified  may  be  entitled under any bylaw,  agreement,  vote  of
shareholders  or  directors or otherwise. Insofar as  indemnification
for liabilities arising under the Securities Act may be permitted  to
directors,  officers or persons controlling the Company  pursuant  to
the  foregoing provisions, the Company has been informed that in  the
opinion  of the Securities and Exchange Commission (the "Commission")
such  indemnification is against public policy as  expressed  in  the
Securities Act and is therefore unenforceable.

Oregon Control Share and Business Combination Statutes

The  Company  is  subject to certain provisions of the  Act  that  in
certain   circumstances   restrict   the   ability   of   significant
shareholders from exercising voting rights (the "Control Share Act").
The   Control  Share  Act  generally  provides  that  a  person  (the
"Acquiring   Person")  who  acquires  voting  stock  of   an   Oregon
corporation  in a transaction that results in the Acquiring  Person's
holding  more than 20%, 33 1/3% or 50% of the total voting  power  of
the  corporation  (a  "Control Share Acquisition")  cannot  vote  the
shares the Acquiring Person acquires in the Control Share Acquisition
("control  shares") unless voting rights are accorded to the  control
shares  by (i) a majority of each voting group entitled to  vote  and
(ii)  the  holders  of a majority of the outstanding  voting  shares,
excluding the control shares held by the Acquiring Person and  shares
held  by  the corporation's officers and inside directors.  The  term
"Acquiring Person" is broadly defined to include persons acting as  a
group.

The  Acquiring  Person may, but is not required  to,  submit  to  the
corporation a statement setting forth certain information  about  the
Acquiring  Person and its plans with respect to the corporation.  The
statement  may  also  request  that the corporation  call  a  special
meeting  of shareholders to determine whether voting rights  will  be
accorded  to  the  control shares. If the Acquiring Person  does  not
request  a special meeting of shareholders, the issue of the  control
shares'  voting  rights  will be considered at  the  next  annual  or
special  meeting  of shareholders. If the Acquiring Person's  control
shares  are  accorded voting rights and represent a majority  of  all
voting  power, shareholders who do not vote in favor of voting rights
for  the  control shares will have the right to receive the appraised
"fair  value" of their shares, which may not be less than the highest
price paid per share by the Acquiring Person for the control shares.

The  Company is subject to certain provisions of the Act that  govern
business    combinations   between   corporations   and    interested
shareholders,  which generally provides that if a  person  or  entity
acquires 15% or more of the voting stock of an Oregon corporation (an
"Interested   Shareholder"),  the  corporation  and  the   Interested
Shareholder,  or any affiliated entity of the Interested Shareholder,
may not engage in certain business combination transactions for three
years following the date the person became an Interested Shareholder.
Business  combination  transactions for this purpose  include  (a)  a
merger  or  plan of share exchange, (b) any sale, lease, mortgage  or
other disposition of 10% or more of the assets of the corporation and
(c) certain transactions that result in the issuance of capital stock
of  the corporation to the Interested Shareholder. These restrictions
do  not  apply if (i) the Interested Shareholder, as a result of  the
transaction  in  which such person became an Interested  Shareholder,
owns  at least 85% of the outstanding voting stock of the corporation
(disregarding shares owned by directors who are also
 <PAGE>
officers and certain employee benefit plans), (ii) the board of
directors approves the share acquisition or business combination
before the Interested Shareholder acquired 15% or more of the
corporation's outstanding voting stock or (iii) the board of
directors and the holders of at least two-thirds of the outstanding
voting stock of the corporation (disregarding shares owned by the
Interested Shareholder) approve the transaction after the Interested
Shareholder acquires 15% or more of the corporation's voting stock.

Transfer Agent and Registrar

The  transfer  agent and registrar for the Common Stock  is  American
Securities Transfer and Trust, Inc., Denver, Colorado.

                        PLAN OF DISTRIBUTION

The Shares may be sold from time to time by the Selling Shareholders,
or  by pledgees, donees, transferees or other successors in interest.
Such sales may be made in the over-the-counter market or otherwise at
prices and at terms then prevailing or at prices related to the  then
current market price, or in negotiated transactions.  The Shares  may
be  sold by one or more of the following:  (a) a block trade in which
the  broker or dealer so engaged will attempt to sell the  Shares  as
agent but may position and resell a portion of the block as principal
to  facilitate the transaction; (b) a purchase by a broker or  dealer
as  principal  and resale by such broker or dealer  for  its  account
pursuant  to this Prospectus; and (c) ordinary brokerage transactions
and  transactions  in  which  the  broker  solicits  purchasers.   In
effecting   sales,  brokers  or  dealers  engaged  by   the   Selling
Shareholders may arrange for other brokers or dealers to participate.
Brokers  or  dealers will receive commissions or discounts  from  the
Selling Shareholders in amounts to be negotiated immediately prior to
the  sale.   Such  brokers  or dealers and  any  other  participating
brokers  or  dealers  may be deemed to be "underwriters"  within  the
meaning  of  the  Securities Act in connection with such  sales.   In
addition, any Shares covered by this Prospectus that qualify for sale
pursuant  to Rule 144 may be sold under Rule 144 rather than pursuant
to this Prospectus.

Under   agreements  that  may  be  entered  into   by   the   Selling
Shareholders,  dealers  who participate in the  distribution  of  the
Shares may be entitled to indemnification by the Selling Shareholders
against   certain  liabilities,  including  liabilities   under   the
Securities Act.

Certain of the dealers may be customers of, including borrowers from,
engage in transactions with, and perform services for, the Company, a
Selling  Shareholder  or  one  or more of  their  affiliates  in  the
ordinary course of business.

                            LEGAL MATTERS

The  validity of the Common Stock offered hereby has been passed upon
by Perkins Coie, Portland, Oregon.

                               EXPERTS

The financial statements incorporated by reference in this Prospectus
and  included in the Annual Report on Form 10-KSB for the year  ended
March  31, 1996 have been audited by Arthur Andersen LLP, independent
public  accountants,  as  indicated  in  their  report  with  respect
thereto, and so incorporated herein in reliance upon the authority of
said  firm  as  experts  in auditing and accounting  in  giving  said
report.
<PAGE>

- ----------------------------      -----------------------------       
   No dealer, salesperson or                       
any  other person  has  been                       
authorized   to   give   any                850,000 Shares
information or to  make  any                       
representations  other  than                       
those   contained  in   this                       
Prospectus   in   connection               SYNTHETECH, INC.
with   the  offer  contained                       
herein,  and,  if  given  or                 Common Stock
made,  such  information  or
representations must not  be
relied  upon as having  been
authorized by the Company or
by   any   of  the   Selling
Shareholders.           This
Prospectus     does      not
constitute an offer  of  any
securities other than  those
to  which it relates  or  an
offer   to   sell,   or    a
solicitation of an offer  to
buy,   those  to  which   it
relates in any state to  any
person  to  whom it  is  not
lawful to make such offer in
such state.  The delivery of
this  Prospectus at any time
does  not  imply  that   the
information    herein     is
correct   as  of  any   time
subsequent to its date.
                                                   
     TABLE OF CONTENTS                             
                        Page                       
Available Information     2                        
Incorporation of Certain                           
Documents by Reference    2                   __________, 1996
Risk Factors              3                        
Selling Shareholders      7
Description of Securities 7
Plan of Distribution      9
Legal Matters             9
Experts                   9
Additional Information II-1
                                                     
- -----------------------------      ------------------------------         
                                                   

<PAGE>
                                  
                               PART II
                                  
               INFORMATION NOT REQUIRED IN PROSPECTUS

<TABLE>
<CAPTION>
<S>                                            <C>
Item 14.  Other Expenses of Issuance and Distribution
                                                      
                                                   Amount
          SEC Registration Fee                  $ 2,198.28
          Accounting Fees and Expenses*           1,000.00
          Legal Fees and Expenses*               30,000.00
          Blue Sky Fees and Expenses*             7,000.00
          Printing, including Registration      
          Statement, Prospectus,                  1,500.00
               etc.*
          Miscellaneous Expenses*                 3,301.72
                                                ----------
          TOTAL EXPENSES*                       $45,000.00
                                                ==========
</TABLE>
_____________

*Estimated

Item 15.  Indemnification of Directors and Officers

As  an  Oregon  corporation the Registrant is subject to  the  Oregon
Business  Corporation Act ("OBCA") and the exculpation from liability
and   indemnification  provisions  contained  therein.  Pursuant   to
Section  60.047(2)(d)  of the OBCA, Article  7  of  the  Registrant's
Articles  of Incorporation (the "Articles") eliminates the  liability
of  the  Registrant's directors to the Registrant or its shareholders
except  for  any  liability related to (i)  breach  of  the  duty  of
loyalty;  (ii)  acts or omissions not in good faith or  that  involve
intentional  misconduct  or a knowing violation  of  law;  (iii)  any
unlawful distribution under ORS 60.367; or (iv) any transaction  from
which the director derived an improper personal benefit.

Section  60.391  of the OBCA allows corporations to  indemnify  their
directors  and  officers  against liability  where  the  director  or
officer  has  acted in good faith and with a reasonable  belief  that
actions  taken  were in the best interests of the corporation  or  at
least  not opposed to the corporation's best interests and, if  in  a
criminal  proceeding,  the  individual had  no  reasonable  cause  to
believe  the  conduct  in  question was  unlawful.  Under  the  OBCA,
corporations may not indemnify against liability in connection with a
claim  by  or  in  the right of the corporation or for  any  improper
personal benefit in which the director or officer was adjudged liable
to   the   corporation.   Section  60.394  of   the   OBCA   mandates
indemnification   for  all  reasonable  expenses  incurred   in   the
successful  defense of any claim made or threatened  whether  or  not
such  claim  was  by  or  in the right of the  corporation.  Finally,
pursuant  to  the  Section  60.401 of the OBCA,  a  court  may  order
indemnification in view of all the relevant circumstances, whether or
not  the director or officer met the good-faith and reasonable belief
standards of conduct set out in Section 60.391 of the OBCA.

Section   60.414  of  the  OBCA  also  provides  that  the  statutory
indemnification  provisions are not deemed  exclusive  of  any  other
rights  to  which  directors or officers  may  be  entitled  under  a
corporation's  articles  of incorporation or bylaws,  any  agreement,
general  or  specific  action  of the board  of  directors,  vote  of
shareholders or otherwise.
<PAGE>
The Articles provide that the Registrant is required to indemnify its
current and former directors to the fullest extent permitted by  law.
Indemnification Agreements executed by all directors and officers  of
the  Registrant obligate the Registrant to indemnify such individuals
for  liabilities  incurred  by  such  individuals  while  serving  as
directors or officers of the Registrant.

Item 16.  Exhibits.
       
Exhibit     Description
Number
       
5.1    Opinion of Perkins Coie regarding legality of the Common
       Stock being registered*
       
23.1   Consent of Arthur Andersen LLP
       
23.2   Consent of Perkins Coie (included in the opinion filed as
       Exhibit 5.1)*
       
24.1   Power of Attorney (see signature page)

_________________
* To be filed by amendment.

Item 17.  Undertakings.

(a)  The undersigned registrant hereby undertakes:

     (1)   To  file, during any period in which offers or  sales  are
     being  made,  a  post-effective amendment to  this  registration
     statement  to include any material information with  respect  to
     the  plan  of  distribution  not  previously  disclosed  in  the
     registration   statement  or  any  material   change   to   such
     information in the registration statement.

     (2)   That,  for the purpose of determining any liability  under
     the Securities Act, each such post-effective amendment shall  be
     deemed  to  be  a  new registration statement  relating  to  the
     securities  offered therein, and the offering of such securities
     at  that  time  shall  be  deemed to be the  initial  bona  fide
     offering thereof.

     (3)   To  remove  from registration by means of a post-effective
     amendment  any of the securities being registered  which  remain
     unsold at the termination of the offering.

     (b)  Insofar as indemnification for liabilities arising under the
       Securities  Act  may be permitted to directors,  officers  and
       controlling persons of the registrant pursuant to the foregoing
       provisions, or otherwise, the registrant has been advised that in the
       opinion of the Commission such indemnification is against public
       policy  as  expressed in the Securities Act and is, therefore,
       unenforceable.  In the event that a claim for indemnification against
       such liabilities (other than the payment by the registrant  of
       expenses incurred or paid by a director, officer or controlling
       person of the registrant in the successful defense of any action,
       suit  or proceeding) is asserted by such director, officer  or
       controlling  person  in connection with the  securities  being
       registered, the registrant will, unless in the opinion of its counsel
       the matter has been settled by controlling precedent, submit to a
       court  of  appropriate jurisdiction the question whether  such
       indemnification by it is against public policy as expressed in the
       Act and will be governed by the final adjudication of such issue.
<PAGE>
                                  
                             SIGNATURES

Pursuant  to  the  requirements of the Securities Act  of  1933,  the
Registrant  certifies that it has reasonable grounds to believe  that
it  meets all of the requirements for filing on Form S-3 and has duly
caused this registration statement to be signed on its behalf by  the
undersigned, thereunto duly authorized, in the City of Albany,  State
of Oregon, on July 15, 1996.
                          
                          SYNTHETECH, INC.
                          
                          
                          
                          By:/s/ M. Sreenivasan
                           M. Sreenivasan
                           President and Chief Executive Officer

Each   person   whose  individual  signature  appears  below   hereby
authorizes  and appoints M. Sreenivasan and Charles B. Williams,  and
each  of them, with full power of substitution and full power to  act
without  the other as his or her true attorney-in-fact and  agent  to
act  in  his or her name, place and stead and to execute in the  name
and  on  behalf  of  each person, individually and in  each  capacity
stated below, and to file any and all amendments to this Registration
Statement, including any and all post-effective amendments.

Pursuant  to  the requirements of the Securities Act  of  1933,  this
registration  statement  has been signed on  July  15,  1996  by  the
following persons in the capacities indicated:
                                                      
               Signature                            Title
                                        
        /s/ M. Sreenivasan              President, Chief Executive
            M. Sreenivasan               Officer and Director
                                        (Principal Executive Officer)
                                        
       /s/ Charles B. Williams          Vice President of Finance
           Charles B. Williams          and Administration, Chief
                                        Financial Officer, Secretary
                                        and Treasurer (Principal
                                        Financial Officer and
                                        Principal Accounting
                                        Officer)
                                        
       /s/ Paul C. Ahrens               Chairman of the Board
           Paul C. Ahrens
         
                                        
       /s/ Howard L. Farkas             Director
           Howard L. Farkas
          
                                        
       /s/ Page E. Golsan, III          Director
           Page E. Golsan, III
<PAGE>
                                   
                           INDEX TO EXHIBIT
                              TO FORM S-3
                         FOR SYNTHETECH, INC.

        
Exhibit     Description
Number
- ------      -----------  
5.1     Opinion of Perkins Coie regarding legality of the Common
        Stock being registered*
        
23.1    Consent of Arthur Andersen LLP
        
23.2    Consent of Perkins Coie (included in the opinion filed
        as Exhibit 5.1)
        
24.1    Power of Attorney (see signature page)

____________________

*    To be filed by amendment.
                                   
                   
                                                               Exhibit 23.1
                                                               to Form S-3
           
               CONSENT OF INDEPENDENT PUBLIC ACCOUNTANTS
                                   
As independent public accountants, we hereby consent to the
incorporation by reference in this Form S-3 registration statement,
registering up to 850,000 shares of common stock, of our report dated
May 16, 1996 included in Synthetech, Inc.'s Form 10-KSB for the year
ended March 31, 1996 and to all references to our firm included in
this registration statement.

                                   ARTHUR ANDERSEN LLP
Portland, Oregon
July 15, 1996



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