SYNTHETECH INC
10KSB, 1997-06-23
INDUSTRIAL ORGANIC CHEMICALS
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<PAGE> 1
             U. S. SECURITIES AND EXCHANGE COMMISSION
                                 
                      Washington, D.C. 20549
                                 
                            FORM 10-KSB
                                 
                            (Mark One)
[X]  ANNUAL REPORT PURSUANT TO SECTION 13 or 15(d) OF THE
     SECURITIES EXCHANGE ACT OF 1934 [Fee Required]
     For the fiscal year ended March 31, 1997

[ ]  TRANSITION REPORT PURSUANT TO SECTION 13 or 15(d) OF THE
     SECURITIES EXCHANGE ACT OF 1934 [No Fee Required]
     For the transition period from __________ to __________
Commission file number 0-12992
                         SYNTHETECH, INC.
          (Name of small business issuer in its charter)
                                                    
                Oregon                         84-0845771
     (State or other jurisdiction           (I.R.S. Employer
     of incorporation or organization)      Identification No.)
              
                                                    
     1290 Industrial Way, Albany, Oregon          97321
     (Address  of  principal  executive         (Zip Code)
      offices)
                                                    
     Issuer's telephone number:               541/967-6575
                                                    
     Securities registered pursuant to           
     Section 12(b) of the Act:                   None
                                                      
     Securities registered pursuant to          
     Section 12(g) of the Exchange Act:
                                 
                   Common Stock, $.001 Par Value
                         (Title of class)
Check whether issuer (1) filed all reports required to be filed  by
Section  13 or 15(d) of the Securities Exchange Act of 1934  during
the  past 12 months (or for such shorter period that the registrant
was  required  to file such reports), and (2) has been  subject  to
such filing requirements for the past 90 days.   YES  X   NO

Check if there is no disclosure of delinquent filers in response to
Item  405  of  Regulation  S-B  contained  in  this  form,  and  no
disclosure   will  be  contained,  to  the  best  of   registrant's
knowledge,   in   definitive   proxy  or   information   statements
incorporated  by reference in Part III of this Form 10-KSB  or  any
amendment to this Form 10-KSB.  [ ]

Issuer's revenues for its most recent fiscal year:  $12,797,132

As of May 23, 1997, the aggregate market value of the voting stock
held  by nonaffiliates of the registrant was $92,411,546 based upon
$8.06 per share.

The number of the shares of the Company's Common Stock outstanding
on May 23, 1997 was 13,859,771.
                                 
Transitional Small Business Disclosure Format (check one):  YES__  NO X

<PAGE> 2
                                
                             PART I
                                
                        ITEM 1.  BUSINESS

Synthetech,  Inc.,  an  Oregon  corporation  (the  "Company"   or
"Synthetech"),  produces Peptide Building Blocks and  other  fine
chemicals   using   a  combination  of  organic   chemistry   and
biocatalysis.

PRODUCT OVERVIEW

Peptide  Building Blocks.  Peptides are short chains of generally
less   than   50   amino  acids  and  are   used   primarily   in
pharmaceuticals.  The production of peptides requires amino acids
which have been chemically modified to enable them to more easily
link with other amino acids in a particular sequence to form  the
desired peptide.  The Company refers to these chemically modified
amino  acids as "Peptide Building Blocks" or "PBBs."   The  amino
acids which are transformed into PBBs may be either natural amino
acids  (that is, amino acids which occur in nature) or  synthetic
amino  acids (that is, amino acids which have a side  chain  that
does not occur in nature).

Synthetech  chemically  modifies natural amino  acids  (which  it
purchases from multiple suppliers) to produce PBBs.  The  Company
also  manufactures synthetic amino acids, and chemically modifies
these synthetic amino acids to produce PBBs.

The  Company  has developed and scaled up process  technology  to
produce  a  wide  range of PBB products at the multi-kilogram  to
multi-ton scale.

The  Company  currently offers over 300 different  PBB  products.
For  the  fiscal years ended March 31, 1997, 1996, and 1995,  the
Company's  sales  of  PBBs  represented 100%  ($12,797,000),  99%
($8,412,000),   and  89%  ($4,759,000),  respectively,   of   the
Company's  total revenues.  For the fiscal years ended March  31,
1997,  1996, and 1995, sales to overseas customers accounted  for
approximately  32%, 21%, and 19%, respectively, of the  Company's
total  revenues.   These  sales were principally  to  Europe  and
Japan.

Other  Fine Chemicals.  The Company is capable of producing other
fine  chemical compounds.  These compounds have included grignard
reagents  and  other fine chemicals conforming to the  customer's
confidential  specifications. As the Company's core  business  in
PBBs  expanded  over  the past three years, the  Company  stopped
actively  marketing these products.  For the fiscal  years  ended
March 31, 1997, 1996, and 1995, the Company's sales of other fine
chemicals  represented 0% ($0), 1% ($60,000), and 10% ($513,000),
respectively,  of  the  Company's  total  revenues.    With   the
completion of the additional processing facility expected in  the
Summer of 1997, the Company may again explore other fine chemical
compounds and custom manufacturing opportunities.
                                
                      _____________________

The  Company  continues to produce most bulk  orders  on  an  as-
ordered  basis, although it does carry an inventory of  over  300
PBB  products.   At  May 23, 1997, the dollar amount  of  backlog
                                1
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orders  which  the Company believed to be firm was  approximately
$2.2  million  (May  31,  1996 backlog was  $5.5  million,  which
included  one large order of $2 million, portions of  which  were
subject to certain  cancellation  provisions).   The  variation  
in  backlog between   May  1997  and  May  1996  underscores  the
continued variability  in the demand for the Company's PBBs  at  
any  given time  (See Item 6, "Management's Discussion and Analysis 
or  Plan of Operations").

In  January  1990, the Company entered into supply and technology
agreements   with   Biomeasure  Incorporated,   a   Boston   area
biotechnology  company and a subsidiary of Groupe  Pharmaceutique
Beaufour-Ipsen of France with several synthetic peptide  products
under  development.  Under the supply agreement, the Company  has
agreed  to  supply  all  of  Biomeasure's  requirements   for   a
particular synthetic PBB.  This agreement continues from year  to
year  unless  terminated in writing by one of the  parties.   The
Company  and  Biomeasure are also parties to a license  agreement
giving Biomeasure the option to receive a license to produce  for
its  own use the PBB which is the subject of the supply agreement
between  the  parties.  Under this license agreement,  Biomeasure
must pay certain royalty amounts based on the amount produced.

MARKET OVERVIEW

The  market  for Peptide Building Blocks is driven by the  market
for  the  peptides in which they are incorporated.  The  size  of
this  market  is a function of the number of peptides  which  are
initially  screened  for use in pharmaceuticals,  the  number  of
these   pharmaceuticals  which  progress  down  the  path  toward
registration and, ultimately, the number which are  found  to  be
therapeutically  useful.   The size  of  the  market  is  also  a
function  of  the quantities and varieties of PBBs  necessary  to
produce  these pharmaceuticals.  Based on an analysis  of  fiscal
1997  PBB  sales  and  information to the extent  available  from
customers,  the Company estimates that approximately 11%  of  the
Company's  PBB  sales  went into marketed  or  "approved"  drugs,
approximately  83%  went  into drugs in  clinical  or  late  pre-
clinical trials and approximately 6% went into drugs at  the  R&D
or discovery stage of development.

MARKETING

The  Company  markets  its products through attendance  at  trade
shows,   listings   in   biotechnology  and   chemical   industry
directories, advertisements in chemical trade periodicals and  by
contacting  pharmaceutical and other companies which it  believes
might have a need for its products.

CUSTOMERS

Although the Company has over 200 customers, the Company  expects
that  a  few customers will continue to account for a significant
portion  of revenues each year.  During fiscal 1997, the  Company
had  three  customers which accounted for 66%  of  the  Company's
revenues,  and two of these customers accounted for  59%  of  the
Company's  revenues and separately accounted  for  30%  and  29%,
respectively, of the revenues.

COMPETITION

Because  peptide-based pharmaceuticals are  relatively  new,  the
market  in  the past for Peptide Building Blocks has  been  quite
small  --  with  most sales in the hundreds of kilos  or  smaller 
size.   
                                   2
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As  a  result,  the  PBB  market  has  not  attracted   a
significant amount of direct competition.  As the market
continues  to  grow  with  multi-ton order  sizes  becoming  more
prevalent, the Company has begun to see more competition.

Current  competition  in  multi-kilo  or  smaller  quantities  of
natural  amino  acid  based  PBBs comes  primarily  from  several
European fine chemical companies. Multi-ton order sizes of  these
natural PBBs have begun to attract a wider group of domestic  and
international chemical companies.  In the area of synthetic amino
acid  based  PBBs,  the Company has competition  on  a  selective
product  basis from fine chemical producers in Europe and  Japan.
Competition    also  increases  for  supplying  PBBs   for   drug
development  programs that reach late clinical  trials  and  move
into  approved  status  as a result of the  increased  quantities
typically  required  at  these stages and pharmaceutical  company
requirements to have second sources of material available.   Many
of  the  Company's competitors have technical, financial, selling
and  other  resources available to them which  are  significantly
greater than those available to the Company.

The  principal methods of competition in the market for PBBs  and
other  fine  chemicals are quality, customer service  and  price.
The  Company  believes that it competes effectively  in  each  of
these areas.  The Company also believes that its production of  a
wide  range  of  products and quantities gives it  a  competitive
advantage in the marketplace.  In addition, the Company  believes
that pharmaceutical companies view internal production of PBBs as
a  misallocation of resources and, given a reliable source  of  a
quality  product,  would  rather  obtain  them  from  an  outside
supplier.

RESEARCH AND DEVELOPMENT

The  Company's  research  and development  efforts  have  focused
principally on process development. During the fiscal years ended
March  31,  1997,  1996,  and 1995, the  Company's  research  and
development  expenses  were  $211,000,  $217,000,  and  $169,000,
respectively.  These figures, however, do not completely  reflect
the Company's research and development activity since substantial
process  development  efforts have been associated  with  initial
orders  for new products and, accordingly, have been expensed  as
cost of sales associated with the product revenue rather than  as
a  research and development expense.  The Company estimates  that
its  combined  research and development effort (including  effort
directly  associated with the sale of product) was  approximately
$346,000,  $364,000  and $293,000 during the fiscal  years  ended
March 31, 1997, 1996 and 1995, respectively.

EMPLOYEES

As of May 23, 1997, the Company employed thirty-four individuals,
two of whom were part-time.

REGULATORY MATTERS

As  the  Company's  products  are  intermediates  sold  to  final
producers,  the  Company  has been generally  unaffected  by  FDA
regulation  which  is  directed at final  products  sold  to  the
public.   The  Company's customers do, however, typically  impose
inspection and quality assurance programs on the Company.   These
programs  involve  materials handling,  recordkeeping  and  other
requirements. As some customers have begun to request the Company
to  provide  additional processing steps,  these  programs  often
                                3
<PAGE> 5
include  more  extensive requirements.  The  Company  anticipates
that  the  expenses of complying with such programs will increase
in the future. 

The  Company's business is also subject to substantial 
regulation in the areas of safety, environmental release and hazardous 
waste disposal.  Although the Company believes that it is in compliance
with  these laws, rules and regulations in all material respects,
the  failure  to comply with present or future regulations  could
result  in  fines  being  imposed on the Company,  suspension  of
production  or  cessation of operations. As additional  and  more
extensive  regulations  are being added in  these  areas  at  the
federal,  state  and  local  levels, the  compliance  costs  will
inevitably  continue  to  increase.  The  operation  of  chemical
manufacturing  plants entails the inherent risk of  environmental
damage  or  personal  injury due to the handling  of  potentially
harmful  substances, and there can be no assurance that  material
costs  and liabilities will not be incurred in the future because
of  an accident or other event resulting in personal injury or an
unauthorized  release  of  such substances  to  the  environment.
Also, the Company generates hazardous and other wastes which  are
disposed  of at various off-site facilities. The Company  may  be
liable,  irrespective  of fault, for material  cleanup  costs  or
other  liabilities incurred at these disposal facilities  due  to
releases of such substances into the environment.

The   Company  maintains  property  damage  insurance,  liability
insurance,  environmental risk insurance, and  product  liability
insurance.

PRODUCT LIABILITY

Use   of  the  Company's  products  in  pharmaceuticals  and  the
subsequent  testing,  marketing and sale of such  pharmaceuticals
involves  an  inherent risk of product liability.   In  addition,
research and development activities in amino acid technology, and
the  production  of fine chemicals (including organic  chemicals)
may  expose workers engaged in performing duties related to  such
activities  to  health hazards.  There can be no  assurance  that
claims  for  product liability will not be asserted  against  the
Company or that the Company would be able to successfully  defend
any  claim that may be asserted.  A product liability claim could
have  a  material adverse effect on the business and/or financial
condition of the Company.

COMPANY BACKGROUND

The  Company was formed in 1981 to develop novel chemical process
technology by combining classical organic chemistry with  enzyme-
based  biocatalysis.  For the first several  years,  it  operated
mainly  as  a  research  and development  group  focused  on  the
production  of  pharmaceuticals and other fine chemicals.   After
its  initial  public  offering in 1984,  the  Company's  research
efforts  were  concentrated on the development of  a  proprietary
process  for aspartame and L-phenylalanine.  Although the Company
had  entered  into one license for this technology,  the  Company
does not expect additional licensing revenue.

Throughout  its  development during the 1980s, the  Company  also
offered contract research services.  These research services were
typically   provided  to  pharmaceutical  clients  and  generally
involved  the  development of biocatalytic  processes  (that  is,
chemical  processes which are affected by the use of  enzymes  or
microorganisms).  Since the end of fiscal 1990, the  Company  has
                               4
<PAGE> 6
phased  out  contract research services and does  not  anticipate
receiving any significant revenue from research services  in  the
future.   By  the end of the 1980s, the Company, building  on  it
prior experience, began to focus on the  production  of PBBs and 
other fine chemicals for  customers.  During  the 1990s, the Company 
has emerged as a leading  producer of PBBs in gram, multi-kilo and 
ton quantities.

FORWARD-LOOKING STATEMENTS

This  Form  10-KSB  includes  "forward-looking"  information  (as
defined  in Section 27A of the Securities Act of 1933 and Section
21E  of  the Securities Exchange Act of 1934) that involve  risks
and  uncertainties,  including, but  not  limited  to,  potential
quarterly  revenue fluctuations, uncertain market  for  products,
technological   change,   customer   concentration,   impact   of
competitive products and pricing and other risks detailed in this
Form  10-KSB and other Securities and Exchange Commission Filings
made by the Company.
                                
                       ITEM 2.  PROPERTIES

Synthetech's headquarters and production facility is  located  in
Albany,  Oregon.   The Company purchased this facility  in  1987.
This   approximately   23,000  square  foot   facility   includes
production, pilot plant, laboratory, warehouse and office space.

The  Company  also  is constructing an additional  20,000  square
foot,   two-story  production  facility  at  its  Albany,  Oregon
location.    The  new  plant  will  substantially  increase   the
Company's  capacity  to  produce PBBs and other  fine  chemicals.
This facility will have six production bays, of which two will be
outfitted immediately with manufacturing equipment and four  will
be  available  for future expansion.  Synthetech  has  contracted
with  various  third party providers relating to its  new  plant.
The  Company  has issued purchase orders to such  providers  with
detailed  specifications, services to be provided and the  prices
to  be  paid.   The  Company has received either  limited  or  no
written  warranties by such third party providers and, therefore,
may  be  limited in its ability to pursue remedies in  the  event
that  the  new  building has problems or  other  defects  in  the
future.  However, the building is being inspected by the City  of
Albany  to  verify that, as constructed, it meets all  applicable
building  codes,  including ADA, electrical,  seismic,  fire  and
hazardous  occupancy.  All specifications  were  reviewed  by  an
independent third-party engineering firm selected by the City  of
Albany  prior  to approval of various construction permits.   The
Company  estimates  that  the cost  of  the  building  shell  and
infrastructure  plus the equipment to be used in  the  first  two
bays  will  be  approximately $7 million and is  expected  to  be
completed during the Summer of 1997. The Company has and  expects
to  continue  to  finance  this capital  expansion  from  working
capital.
                                
                   ITEM 3.  LEGAL PROCEEDINGS

Not applicable.
                                5

<PAGE> 7                                
      ITEM 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY
                             HOLDERS

Not applicable.


                                
                             PART II
                                
          ITEM 5.  MARKET FOR COMMON EQUITY AND RELATED
                       SHAREHOLDER MATTERS

Commencing  on  September 11, 1996, the  Company's  Common  Stock
began trading on the Nasdaq National Market.  Prior to that time,
the  Common Stock was traded on the Nasdaq SmallCap Market.   The
Company's  common stock trading symbol is "NZYM."  The  following
table  sets forth the range of high and low sales prices for  the
Common  Stock for the period on and after September 11, 1996  and
the  high  and low bid quotations for the Common Stock  prior  to
September  11,  1996,  all  as  reported  by  Nasdaq.   The   bid
quotations  reflect inter-dealer prices, without  retail  markup,
markdown  or commission and may not necessarily represent  actual
transactions.
<TABLE>
<CAPTION>                                          
                             Fiscal Year Ended March 31,
                                                       
                            1997                     1996
                                                             
                     High         Low         High         Low
<S>                 <C>         <C>          <C>         <C>                                                         
First Quarter       $10.75      $5.81        $3.06       $2.06
                                                         
Second Quarter        8.25(1)    6.38(1)      4.75        3.06
                                                         
Third Quarter        13.88       6.75         5.25        3.81
                                                         
Fourth Quarter       13.63       6.88         5.88        4.06
</TABLE>
___________________________
(1)bid quotation

No dividends on the Company's Common Stock have been paid since
inception and the Company does not anticipate that dividends will
be paid in the foreseeable future.  The number of record holders
of Common Stock as of May 23, 1997 was approximately 740.
     



RECENT SALES OF UNREGISTERED SECURITIES

On  March 27, 1996, the Company issued 1,000,000 shares of Common
Stock to JB Partners pursuant to the exercise of a warrant for an
aggregate cash consideration of $1 million.  JB Partners
                               6
<PAGE> 8
represented  to the Company that it was an "accredited  investor"
within  the  meaning of Rule 501(a) under the Securities  Act  of
1933  (the  "Securities Act").  The issuance of these  securities
were  exempt  from registration pursuant to Rule 506 and  Section
4(2) of the Securities Act.

The  Company  issued 50,000 shares of Common  Stock  to  Eric  D.
Emanuel   on  September  17,  1996  and  to  Sheldon   Kraft   on
September  19, 1996 pursuant to the exercise of warrants  for  an
aggregate  cash consideration of $222,000.  Messrs.  Emanuel  and
Kraft  each represented to the Company that he was an "accredited
investor"  within the meaning of Rule 501(a) under the Securities
Act.    The  issuance  of  these  securities  were  exempt   from
registration  pursuant  to  Rule 506  and  Section  4(2)  of  the
Securities Act.

On  December 19, 1996, the Company issued 25,000 shares of Common
Stock to Page E. Golsan III pursuant to the exercise of a warrant
for  an  aggregate  cash consideration of  $45,250.   Mr.  Golsan
represented  to the Company that he was an "accredited  investor"
within the meaning of Rule 501(a) under the Securities Act.   The
issuance  of  these  securities  were  exempt  from  registration
pursuant to Rule 506 and Section 4(2) of the Securities Act.


                                
      ITEM 6.  MANAGEMENT'S DISCUSSION AND ANALYSIS OR PLAN
                          OF OPERATIONS

RESULTS OF OPERATIONS

The  following  table sets forth, for the periods indicated,  the
percentage of revenues represented by each item included  in  the
Statements of Income.
<TABLE>
<CAPTION>
                               Percentage of Revenues
                              Fiscal Year Ended March 31,
                                                  
                               1997    1996     1995
<S>                          <C>     <C>      <C>                    
Revenues                      100.0%  100.0%   100.0%
Cost of Sales                  39.9    43.5     48.5
                              -----   -----    -----
Gross Profit                   60.1    56.5     51.5
                                               
Research and Development        1.6     2.6      3.2
Selling, General and            
 Administrative                 9.7     9.8     14.4
                               ----    ----     ----
Operating Income               48.8    44.1     33.9
                                               
Other Income                    3.0     3.4      1.3
Interest Expense                  -       -      0.5
                               ----    ----     ----
Income Before Income Taxes     51.8    47.5     34.7
Provision for Income Taxes     19.7    17.1      8.3
                               ----    ----     ----
Net Income                     32.1    30.4     26.4
                               ====    ====     ====
</TABLE>
                                     7
<PAGE> 9
Revenues
- --------
Synthetech revenues were $12.80 million, $8.47 million, and $5.36
million  in  fiscal  1997,  1996 and  1995,  respectively.   This
reflects  a 51% increase in revenues from fiscal 1996  to  fiscal
1997  and  a 58% increase in revenues from fiscal 1995 to  fiscal
1996.  The growth in revenues during the past two years has  been
attributable  to  increased  product sales  reflecting  continued
market development of the product line of Peptide Building Blocks
(PBBs).   As  a  result of new products and increased  volume  of
existing  products, sales of PBBs, the Company's primary  product
line, were $12.80 million in fiscal 1997, up 52% over fiscal 1996
and $8.41 million in fiscal 1996, up 77% over fiscal 1995.

In  fiscal 1997, based on an analysis of the Company's sales  and
information  to the extent available from customers, the  Company
estimates that approximately 11% of the Company's PBB sales  went
into  marketed or "approved" drugs, approximately 83%  went  into
drugs  in  clinical or late pre-clinical trials and approximately
6%  went  into  drugs at the R&D or discovery stage.   In  fiscal
1996,  the  Company  estimates  that  approximately  12%  of  the
Company's  PBB  sales  went into marketed  or  "approved"  drugs,
approximately  80%  went  into drugs in  clinical  or  late  pre-
clinical trials and approximately 8% went into drugs at  the  R&D
or  discovery stage.  In fiscal 1995, the Company estimates  that
approximately  one-sixth of the Company's  PBB  sales  went  into
marketed or "approved" drugs, approximately two-thirds went  into
drugs  in clinical or late pre-clinical trials, and approximately
one-sixth went into drugs at the R&D discovery stage.

PBB  orders  associated  with two customers  represented  59%  of
revenues  for  fiscal  1997.  Revenues from  these  customers  in
fiscal  1997  were $3.89 million and $3.65 million, respectively,
and  in  fiscal  1996  were  only  $309,000  and  $1.97  million,
respectively.  Sales of this magnitude, relative to the Company's
aggregate  revenues,  demonstrate the  continuing  potential  for
fluctuations  in  revenues from period to period.    Furthermore,
the  customer with purchases of $3.65 million in fiscal 1997, and
a  total  of  nearly  $5.67 million from  February  1995  through
October 1996, advised the Company in September 1996 that  it  was
pursuing  an  alternative, lower-cost manufacturing  process  and
discontinuing  additional  purchases.  While  the  customer  with
purchases  of  $3.89 million in fiscal 1997 continues  to  be  an
important  customer, this customer has indicated that its  future
requirements  will  be based on the project moving  to  the  next
phase of clinical development.

Looking  ahead to fiscal 1998, the Company expects that  it  will
continue  to  be  subject to the same market dynamics  which  can
cause  substantial quarter to quarter revenue fluctuations as  in
fiscal  1997 where the highest revenue quarter was over 2 1/2 times
the  lowest revenue quarter.  Although during the early  part  of
fiscal  1998  the  Company does not foresee working  on  any  PBB
orders  similar  in size to the two major orders last  year,  the
Company   continues  to  believe  strongly   in   the   long-term
opportunities  available  in  this market  niche.   For  example,
during  the  fourth quarter of fiscal 1997, one customer  advised
the Company that Synthetech is a named supplier for a peptide raw
material in their New Drug Application (NDA) filed with the  Food
and  Drug  Administration ("FDA").  However, even with  favorable
progress  of  this  NDA, it is difficult to predict  the  timing,
magnitude and continuity of revenue from this customer.
                               8
<PAGE> 10
The  Company has not yet established a stable baseload of  demand
for  its products.  The Company's products are part of a new  and
emerging  market  with  sizable fluctuations  in  orders  between
periods.  In  most instances, order or reorder cycles for products 
are  not predictable.   Demand for PBBs is extremely  variable  
since  the bulk  of Synthetech's sales involve clinical trial 
programs which are  always  subject to significant risk of suspension  
or  early cancellation.   Further,  only a small  percentage  of  
drugs  in clinical  trial programs are ultimately approved for market  
use.  As  a  result, Synthetech expects to continue to see  similar  
or even  greater fluctuations in its revenue from period to  period.
(See "Industry Factors" below.)

There  were no sales of other fine chemicals or grignard reagents
in  fiscal  1997.   Sales  of grignard reagents  and  other  fine
chemicals  were  $60,000 in fiscal 1996 and  $513,000  in  fiscal
1995.  With  the growth of PBB sales as the core business  focus,
the  Company no longer actively markets grignard and  other  fine
chemical  products.   However, with the  completion  of  its  new
facility  expected in the Summer of 1997, the Company  may  again
explore    other   fine   chemical   and   custom   manufacturing
opportunities.

Gross Profit
- ------------
Gross  profit was $7.70 million, $4.79 million and $2.76  million
in  fiscal  1997, 1996 and 1995, respectively.  This  reflects  a
60.8%  increase in gross profit from fiscal 1996 to  fiscal  1997
and  a  73.5% increase in gross profit from fiscal 1995 to fiscal
1996.   As a percent of revenues, gross profits were 60.1%, 56.5%
and 51.5% in fiscal 1997, 1996 and 1995, respectively.  Increased
revenues  positively affect gross profit margins since a  portion
of  the  Company's  manufacturing overhead costs  are  relatively
fixed.   The  mix  of products sold during any  period  can  also
significantly  affect gross profit margins either  positively  or
negatively.  The increase in the gross profit margins for  fiscal
1997 over fiscal 1996 resulted primarily from the increased level
of  revenues.   The increase in gross profit margins  for  fiscal
1996  and  fiscal  1995  resulted from  the  increased  level  of
revenues combined with the mix of products.  The Company  expects
revenues and product mix to continue to fluctuate from period  to
period and cause variation in gross profit margins.

Operating Expenses
- ------------------
Research and development ("R&D") expense decreased to $211,000 or
1.6%  of sales in fiscal 1997, from $217,000 or 2.6% of sales  in
fiscal  1996.   R&D expense was $169,000 or 3.2% in fiscal  1995.
The  decrease from fiscal 1996 to fiscal 1997 primarily reflected
a  temporary reduction of one technical employee. These  figures,
however,  do  not completely reflect the Company's  research  and
development   activity  since  substantial  process   development
efforts have been associated with initial orders for new products
and,  accordingly, have been expensed as cost of sales associated
with   the  product  revenue  rather  than  as  a  research   and
development  expense.  The Company estimates  that  its  combined
research   and  development  effort  (including  effort  directly
associated with the sale of product) was approximately  $346,000,
$364,000  and  $293,000 during the fiscal years ended  March  31,
1997, 1996 and 1995, respectively.

Selling,  general and administrative ("SG&A") expense  was  $1.24
million,  $833,000 and  $774,000 in fiscal 1997, 1996  and  1995,
respectively.  The increase in SG&A in fiscal  1997  from  fiscal
                               9
<PAGE>  11
1996  principally reflected the addition of one  staff  employee,
base  salary  and  bonus increases, and increases  in  marketing,
director  and  officer  insurance and  expenses  related  to  the
Company's  move to the Nasdaq National Market.  SG&A  expense  in
fiscal 1996 and fiscal 1995 were relatively stable  with the modest 
increase in fiscal 1996 resulting from  a one-time  property  
assessment which  the  Company  expensed  and slight increases in 
other expenses resulting from the significant increase in sales.  
SG&A as a percentage of sales was 9.7%,  9.8% and 14.4% for fiscal 
1997, 1996 and 1995, respectively.

Operating Income
- ----------------
Operating income was $6.25 million in fiscal 1997, $3.74  million
in fiscal 1996 and  $1.82 million in fiscal 1995.  In fiscal 1997
labor  costs (including bonus) increased nearly 23.9%  reflecting
compensation increases and employee additions during  the  fiscal
year.   In  fiscal 1996, labor costs (including bonus)  increased
28.9%,   over   half  of  such  increase  was   attributable   to
compensation  increases  and  the  remainder  resulted  from   an
increase  in  employee hiring beginning in  the  second  half  of
fiscal  1995.   As  a  percentage of revenues,  operating  income
increased  to  48.8% in fiscal 1997 compared to 44.1%  in  fiscal
1996  and   to  33.9% in fiscal 1995.  The increase in  operating
margin  reflected  the  ability of the Company  to  significantly
increase  its  revenues and product volume without  corresponding
increases in operating costs.

Other Income
- ------------
The  $385,000 net other income in fiscal 1997 primarily  resulted
from $376,000 of interest earnings. The $285,000 net other income
in  fiscal  1996  primarily resulted from  $242,000  of  interest
earnings and $43,000 of recognized gain on the sale of securities
available for sale.  The $70,000 net other income in fiscal  1995
primarily  included  $162,000 of interest  earnings,  reduced  by
$38,000  in  realized losses from the sale of marketable  trading
securities, and a $56,000 write down of the Company's holdings of
marketable  trading  securities.  In January  1995,  the  Company
discontinued  its  active  trading policy  with  respect  to  its
marketable securities (see Note B to the Financial Statements for
a more detailed discussion).

Interest expense was $1,000 in fiscal 1997, $0 in fiscal 1996 and
$27,000  in fiscal 1995. Near the end of fiscal 1997, the Company
incurred  $194,000  in  wastewater  system  development   charges
assessed  by the City of Albany in connection with the  Company's
plant expansion.  This fee plus interest on the unpaid portion is
payable over the next ten years. Interest expense for fiscal 1995
was   principally  attributable  to  interest  payments  on   the
Company's SBA loan which was repaid in full in February 1995.

Net Income
- ----------
In  fiscal  1997, the Company earned $6.63 million before  income
taxes.  A provision for income taxes of $2.52 million resulted in
net  income of $4.11 million.  In fiscal 1996, the Company earned
$4.02  million before income taxes.  A provision for income taxes
of  $1.45  million resulted in net income of $2.57 million.   The
provision  for income taxes in fiscal 1996 was lower than  fiscal
1997  primarily because it included a one-time credit of $132,000
from  the  State  of Oregon.  In fiscal 1995, the Company  earned
$1.86  million before income taxes.  A provision for income taxes
                                10
<PAGE> 12
of  $444,000  resulted  in  net income  of  $1.42  million.   The
provision  for income taxes for fiscal 1995 included  utilization
of all remaining federal net operating loss carryforwards.

INDUSTRY FACTORS
- ----------------
The market for PBBs is driven by the market for the peptide-based
drugs  in  which  they  are incorporated.  The  drug  development
process  is dictated by the marketplace, drug companies  and  the
regulatory environment.  The Company has no control over the pace
of  peptide-based drug development, which drugs get selected  for
clinical trials, which drugs are approved by the FDA and, even if
approved, the ultimate potential of such drugs.  Since there  are
only  a  handful of approved peptide-based drugs  on  the  market
today,  this  market  is still very early in  development  and  a
substantial  amount of the activity is occurring at  the  earlier
stages of research and development and clinical trials.

Developments  of  new biological information, based  on  rational
drug  design and combinatorial chemistry, are creating additional
peptide-based   drug   candidates.    Cost   pressures   in   the
pharmaceutical  industry, however, have  tightened  the  criteria
used  to  assess drug prospects at all phases of drug development
programs.  Cost pressures in the pharmaceutical industry can also
cause  pharmaceutical companies to investigate  alternative  drug
manufacturing  processes  which may  not  include  the  Company's
products as an intermediate.

As  a  supplier of building blocks for peptide-based  drugs,  the
Company's  revenue  will be affected by these  industry  factors.
Development cycles typically are quite prolonged.  For  instance,
in  1993 Synthetech began supplying a PBB for clinical trials  to
one customer which recently filed a new drug application with the
FDA.   Similarly, Synthetech began supplying PBBs  at  the  early
development stages in 1990 for a peptide containing product which
Synthetech's   customer  recently  commenced  initial   marketing
efforts.   Also, the high cancellation rate for drug  development
programs results in a significant likelihood that there  will  be
no  subsequent  or "follow-on" PBB sales for any particular  drug
development   program.    Since  the  Company's   revenue   comes
predominantly  from PBBs used in drug development  programs,  the
overall  impact  on the Company's business from the  cancellation
rate  will  depend, to a large extent, on the rate  of  new  drug
development efforts being commenced.

The  advancement of a drug for which Synthetech is providing PBBs
from a drug development program into an "approved" status by  the
FDA  could  also significantly affect the Company's  business  if
Synthetech  is  able  to  continue to supply  the  PBBs  for  the
approved  drug.   With the increased volume typically  associated
with  "approved"  drugs, the Company, however,  expects  to  face
increased competition for this business.

Due  to  the  wide  range of drugs under development  at  various
stages,  sizable fluctuations in orders, and the unpredictability
of  order  or  reorder cycles for products and the other  factors
discussed herein, the Company does not have a stable baseload  of
demand  for its products and cannot estimate the potential market
for   its  products.   Moreover,  the  Company's  customers  vary
substantially from year to year and the Company currently  cannot
rely  on  any one customer as a constant source of revenue.   For
the  foregoing reasons, the Company has experienced in the  past,
and   is   likely  to  experience  in  the  future,   significant
fluctuations in its quarterly results.
                          11
<PAGE>  13

LIQUIDITY AND CAPITAL RESOURCES
- -------------------------------
At   March   31,  1997,  the  Company  had  working  capital   of
$9.24  million compared to $8.16 million at March  31,  1996  and
$3.57  million  at  March  31, 1995.  The  Company's  cash,  cash
equivalents  and  short-term securities  available  for  sale  at
March  31, 1997 totaled $6.92 million.  In addition, the  Company
has  a  $1,000,000 bank line of credit.  This line of  credit  is
secured by the Company's chattel paper, accounts, contract rights
and  general  intangibles.  As of March 31,  1997  there  was  no
amount outstanding under the bank line.

The decrease in accounts receivable to $695,000 at March 31, 1997
from  $1.36  million  at  March 31, 1996  and  from  $840,000  at
March 31, 1995 reflects the lower level of revenues in the fourth
quarter of fiscal 1997 compared to prior years.  The increase  in
income tax receivable to $798,000 at March 31, 1997 from $152,000
at  March 31, 1996 reflects the income tax benefit to the Company
associated  with certain sales of stock by employees  and  others
within  one year of their exercising stock options and  warrants.
Inventory  at  March  31, 1997 decreased to  $1.89  million  from
$1.92 million at March 31, 1996.  Inventory was $1.58 million  at
March 31, 1995.

In  September  1995,  in  response to  approaching  manufacturing
capacity  constraints  in  its  existing  facility,  the  Company
announced plans to construct a new plant to increase its capacity
to  produce  PBBs  and  other  fine chemicals.   The  Company  is
currently  in the later stages of plant construction and  expects
completion of the expansion project during the Summer  of  1997-a
delay  of  a  few months past the original target date  resulting
from   weather  and  permit  delays.   The  overall  engineering,
construction   and   equipment  costs   will   be   approximately
$7  million. The Company is currently operating three  production
shifts,  five days a week at its present facility.  See  Item  2,
"Properties."

The  Company's  capital  costs were approximately  $5.29  million
during  fiscal  1997, $4.55 million of which were for  the  plant
expansion and $740,000 for the existing plant and equipment.   In
addition  to  the completion of the new plant which  the  Company
expects   will   cost  an  additional  amount  of   approximately
$2.2  million  in fiscal 1998, the Company currently  anticipates
acquiring up to $500,000 of additional equipment and upgrades for
the   existing  plant  and  equipment during  fiscal  1998.   The
Company   expects  to  finance  a  majority  of   these   capital
expenditures from internal cash flow.

The  Company  owns  its facility and all of its  equipment.   See
Note D of the Notes to Financial Statements for a description  of
the Company's property, plant and equipment.
                               12
<PAGE> 14

                                
                  ITEM 7.  FINANCIAL STATEMENTS

                      Index                                         Page

Report of Independent Public Accountants for the years ended
March 31, 1997, 1996 and 1995...............................         14

Financial Statements:

  Balance Sheets as of March 31, 1997 and 1996..............         15

  Statements of Income for the years ended March 31, 1997,
   1996 and 1995............................................         17

  Statements of Shareholders' Equity for the years ended
   March 31, 1997, 1996 and 1995............................         18

  Statements of Cash Flows for the years ended March 31,
   1997, 1996, and 1995.....................................         19

Notes to Financial Statements:

  Note A - General and Business.............................         20

  Note B - Summary of Significant Accounting Policies.......         20

  Note C - Inventories......................................         21

  Note D - Property, Plant and Equipment....................         21

  Note E - Income Taxes.....................................         22

  Note F - Line of Credit...................................         22

  Note G - Note Payable.....................................         23

  Note H - Shareholders' Equity.............................         23

  Note I - 401(k) Profit Sharing Plan.......................         25

  Note J - Segment Information..............................         26

  Note K - New Accounting Pronouncement.....................         26
                                     13
<PAGE> 15
REPORT OF INDEPENDENT PUBLIC ACCOUNTANTS

To the Board of Directors and Shareholders of Synthetech, Inc.:

We  have  audited the accompanying balance sheets of  Synthetech,
Inc.  (an Oregon corporation) as of March 31, 1997 and 1996,  and
the  related statements of income, shareholders' equity and  cash
flows  for each of the three years in the period ended March  31,
1997.   These financial statements are the responsibility of  the
Company's  management.   Our  responsibility  is  to  express  an
opinion on these financial statements based on our audits.

We  conducted  our  audit in accordance with  generally  accepted
auditing  standards.  Those standards require that  we  plan  and
perform  the  audit to obtain reasonable assurance about  whether
the  financial statements are free of material misstatement.   An
audit  includes  examining, on a test basis, evidence  supporting
the amounts and disclosures in the financial  statements.   An  
audit also  includes  assessing  the accounting  principles  used 
and significant  estimates  made  by management, as well as 
evaluating the overall financial statement presentation.   We 
believe that our audits provide  a  reasonable basis for our opinion.

In  our  opinion,  the  financial statements  referred  to  above
present  fairly, in all material respects, the financial position
of  Synthetech,  Inc.  as of March 31, 1997  and  1996,  and  the
results  of  its operations and its cash flows for  each  of  the
three years in the period ended March 31, 1997 in conformity with
generally accepted accounting principles.


Arthur Andersen LLP
Portland, Oregon,
May 16, 1997
                                 14
<PAGE> 16
<TABLE>
<CAPTION>
                             SYNTHETECH, INC.                               

                              BALANCE SHEETS                                  
                            ------------------                          
At  March 31,                                      1997             1996
- ------------------                                 ----             ----
<S>                                            <C>              <C>
             ASSETS                                                            
             ------                                                            
CURRENT ASSETS:                                                                
  Cash and cash equivalents                    $   6,740,000    $   5,049,000
  Securities available for sale                      176,000          395,000
  Accounts receivable, less allowance                                          
    for doubtful accounts of $15,000 for                                       
    1997 and 1996                                    695,000        1,355,000
  Inventories                                      1,887,000        1,924,000
  Prepaid expenses                                   164,000           71,000
  Income tax receivable                              798,000          152,000
  Deferred income taxes                               56,000           59,000
  Other current assets                                 4,000            1,000
                                                  ----------       ----------
    TOTAL CURRENT ASSETS                          10,520,000        9,006,000

PROPERTY, PLANT AND EQUIPMENT, at cost, net        6,339,000        1,311,000

SECURITIES AVAILABLE FOR SALE                        450,000          626,000

OTHER ASSETS                                          14,000           16,000
                                                  ----------       ----------
    TOTAL ASSETS                               $  17,323,000    $  10,959,000
                                               =============    =============
</TABLE>                                            
                     See notes to financial statements. 
                                        15
<PAGE> 17
<TABLE>
<CAPTION>

                                    SYNTHETECH, INC.                

                                     BALANCE SHEETS                    
                                   -------------------
                                      (continued)                   
                        
At March 31,                                        1997           1996
- ------------                                         ----           ----
<S>                                             <C>             <C>       
  LIABILITIES AND SHAREHOLDERS' EQUITY                                         
  ------------------------------------                                         
CURRENT LIABILITIES:                             
  Current portion of note payable                $     13,000   $          -
  Accounts payable                                    543,000        271,000
  Accrued compensation                                674,000        479,000
  Deferred revenue                                     44,000         98,000
  Other accrued liabilities                             4,000          1,000
                                                  -----------    -----------
    TOTAL CURRENT LIABILITIES                       1,278,000        849,000

DEFERRED INCOME TAXES                                  68,000         10,000

NOTE PAYABLE, net of current portion                  180,000              -

SHAREHOLDERS' EQUITY:                                                          
  Common stock, $.001 par value; authorized                                    
   100,000,000 shares; issued and outstanding,                                 
   13,860,000 and 13,475,000 shares                    14,000         13,000
  Paid-in capital                                   8,296,000      6,589,000
  Employee notes receivable and deferred                                       
   compensation                                      (239,000)      (130,000)
  Unrealized gain on securities available for sale     16,000         30,000
  Retained earnings                                 7,710,000      3,598,000
                                                  -----------    -----------
    TOTAL SHAREHOLDERS' EQUITY                     15,797,000     10,100,000
                                                  -----------    -----------
    TOTAL LIABILITIES AND SHAREHOLDERS' EQUITY  $  17,323,000  $  10,959,000
                                                =============  =============
</TABLE>        
                         See notes to financial statements.                 
                                       16
<PAGE> 18
<TABLE>
<CAPTION>

                                  SYNTHETECH, INC.            

                                STATEMENTS OF INCOME                        
                                --------------------    

For The Years Ended March 31,                1997         1996         1995
- -----------------------------             ----------   ----------   ----------
<S>                                      <C>           <C>          <C>     
REVENUES                                 $12,797,000   $8,472,000   $5,357,000
COST OF SALES                              5,103,000    3,685,000    2,598,000
                                          ----------   ----------   ----------
GROSS PROFIT                               7,694,000    4,787,000    2,759,000
                                          ----------    ---------   ----------
  Research and development                   211,000      217,000      169,000
  Selling, general and administrative      1,235,000      833,000      774,000
                                           ---------    ---------      -------
OPERATING EXPENSE                          1,446,000    1,050,000      943,000
                                           ---------    ---------    ---------
OPERATING INCOME                           6,248,000    3,737,000    1,816,000
            
OTHER INCOME                                 385,000      285,000       70,000
INTEREST EXPENSE                               1,000            -       27,000
                                           ---------     --------      -------
INCOME BEFORE INCOME TAXES                 6,632,000    4,022,000    1,859,000
                                  
PROVISION FOR INCOME TAXES                 2,520,000    1,448,000      444,000
                                           ---------    ---------    ---------
NET INCOME                              $  4,112,000 $  2,574,000 $  1,415,000
                                          ==========   ==========   ==========
                                     
NET INCOME PER COMMON SHARE                    $0.29        $0.19        $0.11
                                               =====        =====        =====
SHARES USED IN PER SHARE                                       
 CALCULATION                              14,117,041   13,727,960   12,969,701
                                          ==========   ==========   ==========
</TABLE>             
                        See notes to financial statements.
                                            17
<PAGE> 19
<TABLE>
<CAPTION>
                                      SYNTHETECH,INC.    

                              STATEMENTS OF SHAREHOLDERS' EQUITY
                              ---------------------------------- 

For the Years Ended March 31,                                                                 
- -----------------------------
<S>                         <C>         <C>    <C>        <C>         <C>        <C>            
                                                          EMPLOYEE    UNREALIZED  
                                                            NOTES       GAIN ON   RETAINED
                                                          RECEIVABLE  SECURITIES  EARNINGS
                             ---COMMON STOCK---  PAID-IN  & DEFERRED  AVAILABLE (ACCUMULATED)        
                               SHARES    AMOUNT  CAPITAL  COMPENSATION  FOR SALE  DEFICIT)  
                             ---------- ------- ---------- -----------  -------  ----------
BALANCE, March 31, 1994      12,011,000 $12,000 $5,152,000   $     -   $     -  ($391,000)
                                                                                              
Issuance of stock for the                                                      
  exercise of stock options      43,000       -     37,000          -         -          -
Income tax benefit of 
  disqualifying dispositions          -       -      7,000          -         -          -
Unrealized gain on securities                                                          
  available for sale                  -       -          -          -    27,000          -
Net income                            -       -          -          -         -  1,415,000
                             ----------  ------  ---------   --------    ------  ---------
BALANCE, March 31, 1995      12,054,000  12,000  5,196,000          -    27,000  1,024,000        
Issuance of stock for the                                                      
  exercise of stock options     421,000       -    255,000          -         -          -
Issuance of stock for the                                                       
  exercise of stock warrant   1,000,000   1,000    992,000          -         -          -
Issuance of below market 
  stock options                       -       -     70,000    (70,000)        -          -
Amortization of deferred 
  compensation                        -       -          -     20,000         -          -
Employee notes receivable             -       -          -    (80,000)        -          -
Income tax benefit of 
  disqualifying dispositions          -       -     76,000          -         -          -
Unrealized gain on securities                                                                
  available for sale                  -       -          -          -     3,000          -
Net income                            -       -          -          -         -  2,574,000
                             ----------  ------  ---------  ---------    ------  ---------
BALANCE, March 31, 1996      13,475,000  13,000  6,589,000   (130,000)   30,000  3,598,000

Issuance of stock for the 
  exercise of stock options     260,000   1,000    322,000          -         -          -
Issuance of stock for the 
  exercise of stock warrants    125,000       -    228,000          -         -          -
Issuance of below market stock 
  options                             -       -    284,000   (284,000)        -          -
Amortization of deferred 
  compensation                        -       -          -    125,000         -          -
Payment on employee note 
  receivable                          -       -          -     50,000         -          - -      -
Income tax benefit of 
  exercise of stock warrants          -       -    216,000          -         -          - 
Income tax benefit of 
  disqualifying dispositions          -       -    657,000          -         -          - 
Unrealized loss on securities                                                                
  available for sale                  -       -          -          -   (14,000)         -
Net income                            -       -          -          -         -  4,112,000
                             ---------- ------- ----------  ----------  ------- ----------            
BALANCE, March 31, 1997      13,860,000 $14,000 $8,296,000  ($239,000)  $16,000 $7,710,000                      
                             ========== ======= ==========  ==========  ======= ==========
</TABLE>                                           18
                           See notes to financial statements.
<PAGE> 20
<TABLE>
<CAPTION>

                                           SYNTHETECH, INC.
                                       STATEMENTS OF CASH FLOWS 
                                       ------------------------     
                                  
For The Years Ended March 31,                1997         1996         1995
- -----------------------------             ----------   ----------   ----------
<S>                                      <C>          <C>          <C>
CASH FLOWS FROM OPERATING ACTIVITIES:                                         
Net income                                $4,112,000   $2,574,000   $1,415,000
Adjustments to reconcile net income to                                        
  net cash provided by operating                                              
  activities-
    Depreciation, amortization and
     other                                   268,000      205,000      165,000
    Amortization of deferred
     compensation                            105,000       20,000            -
    Gain on sales of property, plant
     and equipment                                 -            -      (18,000)
    Loss on marketable trading
     securities                                    -            -       95,000
    Purchases of marketable trading
     securities                                    -            -     (944,000)
    Proceeds from sale of marketable
     trading securities                            -            -      906,000 
    Accrued interest on securities
     available for sale                        9,000       13,000            -
    Realized gain on securities
     available for sale                      (10,000)     (43,000)           -
    Deferred income taxes                     61,000      (16,000)     (22,000)
    (Increase) decrease in assets:                                            
      Accounts receivable, net               660,000     (515,000)    (328,000)
      Inventories                             37,000     (343,000)     (84,000)
      Prepaid expenses                       (93,000)     (17,000)       2,000
      Income tax receivable                 (646,000)    (152,000)           -
      Other assets                            (1,000)       6,000       (6,000)
    Increase (decrease) in liabilities:                                       
      Accounts payable and accrued
       liabilities                           470,000      355,000       (6,000)
      Deferred revenue                       (54,000)      98,000            -
                                          ----------   ----------   ----------
        Net cash provided by operating
         activities                        4,918,000    2,185,000    1,175,000
                                          ----------   ----------   ----------
CASH FLOWS FROM INVESTING ACTIVITIES:                                         
   Property, plant and equipment
    purchases                             (5,079,000)    (461,000)    (218,000) 
   Proceeds from sale of securities 
    available for sale                             -            -       18,000
   Proceeds from redemption of
    securities available for sale            380,000      882,000            -
   Employee notes receivable                  50,000      (80,000)           -
                                          ----------   ----------   ----------
        Net cash provided by (used by)   
         investing activities             (4,649,000)     341,000     (200,000)
                                          ----------   ----------   ----------
CASH FLOWS FROM FINANCING ACTIVITIES:                                         
   Principal payments under long-term
    debt obligations                          (1,000)           -     (399,000)
   Proceeds from stock option exercises                       
    and disqualifying dispositions           979,000      331,000       44,000
   Proceeds from stock warrant                               
    exercises, including tax benefit         444,000      993,000            -
                                          ----------   ----------   ----------
        Net cash provided by (used by)
         financing activities              1,422,000    1,324,000     (355,000)
                                          ----------   ----------   ----------
NET INCREASE IN CASH AND CASH                               
 EQUIVALENTS                               1,691,000    3,850,000      620,000
CASH AND CASH EQUIVALENTS AT BEGINNING                               
 OF YEAR                                   5,049,000    1,199,000      579,000
                                          ----------   ----------   ----------
CASH AND CASH EQUIVALENTS AT END OF
 YEAR                                     $6,740,000   $5,049,000   $1,199,000
                                         ===========  ===========  ===========
NON-CASH INVESTING AND FINANCING                               
 ACTIVITIES:
   Unrealized gain (loss) on securities
    available for sale                     ($14,000)       $3,000      $27,000
   Issuance of stock options at below
    fair value                             $284,000       $70,000            -
   Issuance of note payable for capital
    improvement                            $194,000             -            -
</TABLE>    
                                 See notes to financial statements.
                                                19

<PAGE> 21


                           SYNTHETECH, INC.
                     NOTES TO FINANCIAL STATEMENTS
          
NOTE A.   GENERAL AND BUSINESS
          
          Synthetech, Inc., an Oregon corporation, produces  specialty
          amino acids and other fine chemicals using a combination  of
          organic  chemistry and biocatalysis.  The Company's  primary
          product emphasis is on specialty amino acids referred to  as
          Peptide  Building  Blocks which are  sold  domestically  and
          internationally   to   companies  developing   peptide-based
          pharmaceuticals.

NOTE B.   SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES
          
          Use  of  Estimates:  The preparation of financial statements
          in  conformity with generally accepted accounting principles
          requires  management to make estimates and assumptions  that
          affect  the  reported amounts of assets and liabilities  and
          disclosure of contingent assets and liabilities at the  date
          of  the  financial  statements and the reported  amounts  of
          revenues  and expenses during the reporting period.   Actual
          results could differ from those estimates.
          
          Cash  and  Cash  Equivalents:   Cash  and  cash  equivalents
          include  demand cash and all investments purchased  with  an
          original maturity of three months or less.
          
          Securities  Available  For  Sale:   In  January,  1995,  the
          Company  discontinued its active trading policy with respect
          to   its   marketable  securities,  due  to  current  market
          conditions.  The Company no longer intends to actively trade
          these  marketable securities.  The securities  may  be  held
          until  maturity depending upon the Company's cash flow needs
          or   until   changes  in  the  investment  markets   dictate
          otherwise.   Accordingly, all investments as  of  March  31,
          1997  and  1996 have been reflected as securities  available
          for  sale  and  any unrealized gain or loss reflected  as  a
          separate  component  of shareholders' equity  in  accordance
          with SFAS 115.
          
          Securities  available for sale consist mostly of  government
          obligations which mature during 1998 and 1999.  The  Company
          determines cost basis in its investments using the  specific
          identification method.  As of March 31, 1997 and  1996,  the
          difference  between the fair market value and  cost  of  the
          Company's investments were insignificant.
          
          Property,   Plant  and  Equipment:   Property,   plant   and
          equipment   are   recorded   at  cost.    Depreciation   and
          amortization are provided on the straight-line method over 
          seven to forty years for buildings and land improvements, and 
          five to seven years  on  all  other property.  When property  
          is  sold  or retired, the cost and accumulated depreciation 
          reserves  are removed from the accounts and the resulting gain 
          or loss  is included in income.
          
          Revenue Recognition:  Sales of products are recognized  when
          products are shipped.
          
          Research  and  Development Costs:  Research and  development
          costs are expensed as incurred.
          
          Other  Assets:   Other  assets  primarily  represent  patent
          costs,  which  are  amortized over the useful  life  of  the
          patent.
                              
          Earnings  Per  Share:  Net  income  per  common  and  common
          equivalent   share,   as  presented  on   the   accompanying
          Statements of Income is calculated by dividing net income by
          the weighted average number of common stock and common stock
          equivalents outstanding during the period,
                                    20
<PAGE> 22

NOTE B.   SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (continued)
          
          calculated  using  the treasury stock method  in  accordance
          with  APB  Opinion 15,  "Earnings per Share."  The Company's
          common stock equivalents consist of dilutive shares issuable
          upon  the  exercise of outstanding common stock options  and
          warrants.   The shares used in the basic earnings per  share
          calculation   for  1997,  1996  and  1995  were  13,659,927,
          12,255,635  and 12,029,908, respectively, while  the  shares
          used  in  the earnings per share calculation for 1997,  1996
          and   1995   were  14,117,041,  13,727,960  and  12,969,701,
          respectively.
          
          Supplemental cash flow disclosures are as follows:
            Cash Paid During The Year For:
<TABLE>
<CAPTION>
<S>                          <C>           <C>           <C>
                                 1997         1996          1995
               Income Taxes  $ 2,232,000   $ 1,586,000    $ 430,000
               Interest      $     1,000   $         -    $  29,000
</TABLE>

NOTE C.   INVENTORIES
          
          Inventories  are  stated at the lower  of  cost  or  market,
          determined  on the first-in, first-out (FIFO)  basis.   Cost
          utilized for inventory purposes include labor, material, and
          manufacturing overhead.
          
          The major components of inventories are as follows:
<TABLE>
<CAPTION>
<S>                                  <C>         <C>
                                            March 31,
                                         1997        1996
               Finished products     $  779,000  $  685,000
               Work-in-process          440,000     414,000
               Raw materials            668,000     825,000
                                     ----------  ----------          
                                     $1,887,000  $1,924,000
                                     ==========  ==========
</TABLE>


NOTE D.   PROPERTY, PLANT AND EQUIPMENT
          
          Property, plant and equipment consist of the following:
<TABLE>
<CAPTION>
<S>                                        <C>         <C>
                                                   March 31,
                                               1997        1996
               Land                        $   91,000   $   91,000
               Buildings                      658,000      594,000
               Machinery and equipment      1,561,000    1,115,000
               Laboratory equipment           286,000      276,000
               Furniture and fixtures         161,000      106,000
               Vehicles                        26,000       26,000
               Construction in progress     4,977,000      259,000
                                           ----------   ----------
                                            7,760,000    2,467,000
               Less:
               Accumulated depreciation     1,421,000    1,156,000
                                           ----------    ---------      
                                           $6,339,000   $1,311,000
                                           ==========   ========== 
</TABLE>
                                         21
<PAGE> 23
NOTE E.   INCOME TAXES
          
          The  Company accounts for income taxes under the  asset  and
          liability  method as defined by the provisions of  Statement
          of  Financial  Accounting  Standards  No.  109  (SFAS  109),
          Accounting  for  Income Taxes. Under this  method,  deferred
          income  taxes are recognized for the future tax consequences
          attributable to temporary differences between the  financial
          statement  carrying  amounts and tax  balances  of  existing
          assets and liabilities.  Deferred tax assets and liabilities
          are  measured using the enacted rates expected to  apply  to
          taxable   income   in  the  years  which   those   temporary
          differences are expected to be recovered or settled.
          
          The  provision  for income taxes in fiscal 1997  includes  a
          deferred tax provision of $61,000.  The provision for income
          taxes  in fiscal 1996 and fiscal 1995 includes deferred  tax
          benefits of  $16,000 and $22,000, respectively.
          
          Total deferred tax assets and liabilities at March 31,  1997
          were $56,000 and $68,000, respectively.  Total deferred  tax
          assets  and liabilities at March 31, 1996, were $59,000  and
          $10,000,   respectively.    There   were   no   individually
          significant temporary differences at March 31, 1997 or 1996.
          
          The  reconciliation between the effective tax rate  and  the
          statutory federal income tax rate is as follows:
<TABLE>
<CAPTION>
<S>                                           <C>      <C>      <C>
                                               1997     1996     1995
               Statutory federal tax rate      34.0%    34.0%    34.0%
               Federal net operating           
                loss utilized                     -        -     (5.9)%
               Federal general business
                credit utilized                   -        -     (6.9)%        
               Federal alternative  
                minimum tax (credit)              -        -     (1.7)%
               State taxes                      4.4%     2.0%     4.4%
               Foreign sales  
                corporation benefit            (1.5)%      -        -
               Other                            1.1%       -        -
                                               -----    -----    -----
                Effective tax rate             38.0%    36.0%    23.9%
                                               =====    =====    =====
</TABLE>


NOTE  F.  LINE OF CREDIT
          
          The  Company has a line of credit available with a  bank  in
          the amount of $1 million with an applicable interest rate of
          8.5%  at  March 31, 1997.  There were no amounts outstanding
          under this loan at the end of the fiscal year.  This line of
          credit is renewable on an annual basis.
                                         22
<PAGE> 24

NOTE G.   NOTE PAYABLE
          
          The  Company  entered into a note payable with the  City  of
          Albany  for payment of wastewater system development charges
          assessed  in connection with the Company's plant  expansion.
          The  note  bears  interest of 9.0% and  is  due  on  monthly
          installments of $2,459 through February 2007.  The  note  is
          secured by the building under construction.
          
NOTE H.   SHAREHOLDERS' EQUITY

          On March 27, 1996, JB Partners exercised the warrant
          purchased as part of a stock and warrant sale in 1991.  The
          exercise price of the 5-year, nontransferable warrant was
          $1.00 per share and the net proceeds to the Company were
          $993,000.
          
          On September 17 and 19, 1996 the Emanuel and Company warrant
          authorized by the Board of Directors on February 5, 1992 was
          exercised.   The  exercise price of the 5-year  warrant  for
          100,000  shares was $2.22 per share.  On December  19,  1996
          Mr. Page Golsan, III exercised the warrant authorized by the
          Board  of Directors on January 7, 1992.  The exercise  price
          of the 5-year warrant for 25,000 shares was $1.81 per share.
          The  net  proceeds of these warrant exercises was  $228,000.
          As   of  March  31,  1997,  there  were  no  stock  warrants
          outstanding.
          
          During 1995, the Financial Accounting Standards Board issued
          SFAS  No.  123  which defines a fair value based  method  of
          accounting  for  an employee stock option or similar  equity
          instrument and encourages all entities to adopt that  method
          of  accounting for all of their employee stock  compensation
          plans.   However, it also allows an entity  to  continue  to
          measure  compensation cost for those plans using the  method
          of  accounting prescribed in APB 25.  Entities  electing  to
          remain  with  the accounting in APB 25 must make  pro  forma
          disclosures  of net income and, if presented,  earnings  per
          share,  as  if  the  fair value based method  of  accounting
          defined in the Statement had been applied.
          
          The  Company  has  elected to account  for  its  stock-based
          compensation  plan under APB 25.  However, the  Company  has
          computed,  for pro forma disclosure purposes, the  value  of
          all options granted during fiscal 1997 and fiscal 1996 using
          the Black-Scholes option-pricing model as prescribed by SFAS
          No.  123,  using the following weighted average  assumptions
          for grants in fiscal 1997 and fiscal 1996:
<TABLE>
<CAPTION>
<S>                                               <C>         <C>
                                                       Fiscal Year
                                                    1997        1996
                                                    ----        ----
                  Risk-free interest rate           6.49%       6.26%
                  Expected dividend yield              0%          0%
                  Expected life                     3.89 years  3.89 years
                  Expected volatility              49-50%      49-67%
</TABLE>
          
          
                                       23          
<PAGE> 25

NOTE H.   SHAREHOLDERS' EQUITY (CONTINUED)
          
          The  total value of options granted during fiscal  1997  and
          fiscal 1996 would be amortized on a pro forma basis over the
          vesting  period  of  the  options.  Options  generally  vest
          equally  over  two years.  If the Company had accounted  for
          these options in accordance with SFAS No. 123, the Company's
          net income and net income per share would have decreased  as
          reflected in the following pro forma amounts:
<TABLE>
<CAPTION>
<S>                                         <C>            <C>
                                              Years ended March 31,
                                                1997          1996
                                                ----          ----          
               Net income:
                    As reported              $4,112,000     $2,574,000
                    Pro forma                $3,461,000     $2,390,000
               Net income per share:
                    As reported                  $ 0.29        $  0.19
                    Pro forma                    $ 0.25         $ 0.18
</TABLE>
          
          Under  the  Amended  and  Restated 1990  Stock  Option  Plan
          1,600,000 shares were authorized for issuance.  A  total  of
          1,491,160 options were granted under this plan.  A total  of
          864,240 options have been exercised and 55,110 options  have
          been cancelled as of March 31, 1997 under the plan since its
          inception.  The options granted under this plan vest over  a
          two  year  period from the beginning of the fiscal  year  in
          which the options are granted and a maximum term of 5 years.
          
          The  1995  Incentive  Compensation Plan  authorized  902,000
          shares  of the Company's stock to be issued.  This  Plan  is
          the  successor to the Amended and Restated 1990 Stock Option
          Plan.   No  further grants will be made under  the  original
          Plan.   A  total of 349,000 options have been granted  under
          this plan.  A total of 3,000 options have been exercised and
          4,000 options have been cancelled as of March 31, 1997 under
          the  plan  since its inception.  The options  granted  under
          this  plan  generally  vest  from  50%  after  one  year  of
          employment and 100% after 2 years of employment, however, to
          a  lesser extent, some options vest in less than a year  and
          others  up  to five years. Options granted under  this  Plan
          have  a  maximum  term  of  10 years.   The  1995  Incentive
          Compensation  Plan was amended in November  1996  to  permit
          granting of non-qualified options to directors who  are  not
          employees of the Company.
          
                                       24  
          
<PAGE> 26

NOTE H.   SHAREHOLDERS' EQUITY (CONTINUED)


          Activity  under the Amended and Restated 1990  Stock  Option
          Plan and 1995 Incentive Compensation Plans over the last two
          fiscal years is summarized as follows:
<TABLE>
<CAPTION>
<S>                                     <C>      <C>     <C>      <C> 
          Years ended March 31,                1997             1996
                                               ----             ----
                                                    Wtd.             Wtd.
                                                    Avg.             Avg.
                                                     Ex.              Ex.
                                          Shares   Price   Shares   Price
                                         _______   _____   _______  _____
         Options outstanding at
          beginning of year              871,960   $2.02  1,059,499  $1.36
         Granted                         330,000   $7.40    269,000  $2.67
         Exercised                      (275,950)  $1.58   (450,789) $0.85
         Cancelled                       (12,200)  $4.70     (5,750) $2.61
                                        --------   -----   --------  -----
        Options outstanding at
          end of year                    913,810   $4.06    871,960  $2.02
                                         =======   =====    =======  =====
         
         Exercisable at end of year     484,010   $2.08    512,710   $1.64
 
         Weighted average fair value
          of options granted at
          market value                        -   $3.78          -   $1.57
  
         Weighted average fair value
          of options granted at below
          market value                        -   $5.86          -   $2.68     
</TABLE>
          
          
        The  following  table sets forth the exercise price range,  number  of
        shares  outstanding  at  March 31, 1997,  weighted  average  remaining
        contractual   life,  weighted  average  exercise  price,   number   of
        exercisable  shares and weighted average exercise price of exercisable
        options by groups of similar price and grant date:
<TABLE>
<CAPTION>
<S>    <C>            <C>         <C>          <C>        <C>           <C>
                      Options Outstanding                Options exercisable
       -----------------------------------------------  ----------------------
                                 Weighted
                                 Average       Weighted               Weighted
        Exercise     Outstanding Remaining     Average                Average
        Price        Shares      Contractual   Exercise  Exerciseable Exercise
        Range        at 3/31/97  Life(years)   Price       Options     Price
        ----------    -------    -----         -----       --------    ----- 
        $0.30-$0.51    16,000     8.68         $0.44         10,500    $0.41
        $1.72-$1.81   257,460     2.73         $1.74        223,960    $1.73
        $2.22-$2.84   364,350     2.71         $2.59        249,550    $2.47
        $7.50-$8.50   276,000     9.21         $8.39              -        -
</TABLE>

NOTE I.   401(k) PROFIT SHARING PLAN
          
          The  Company  established a 401(k) Profit  Sharing  Plan  on
          April  1, 1992.  This plan is offered to eligible employees,
          who  may  elect to contribute up to 15% of compensation  and
          includes  a  Company  matching contribution.   Beginning  in
          April  1996,  the  Company amended the Plan  to  change  the
          matching contribution to $.50, $.75 and $1.00 for each $1.00
          contributed  up  to  10%  of compensation  corresponding  to
          length of service with the Company.  Prior to this amendment
          the  Company matching contribution was $.50 for  each  $1.00
          contributed by each employee up to 10% of compensation.  The
          Company  contribution becomes fully vested for each employee
          after   5   years  of  employment.   The  Company   matching
          contribution  for  fiscal years 1997,  1996,  and  1995  was
          $77,000, $42,000 and $37,000, respectively.
                                    25          
<PAGE> 27
NOTE J.   SEGMENT INFORMATION
          
          Significant Customers:  During fiscal year 1997, two
          customers accounted for 30% and 29% of revenues.  During
          fiscal year 1996, two customers accounted for 23% and 11% of
          revenues. During fiscal year 1995, two customers accounted
          for 27% and 11% of revenues.

          The  following table reflects foreign sales and  percent  of
          total sales by country:
<TABLE>
<CAPTION>
<S>                <C>        <C>     <C>        <C>    <C>       <C>

                          1997               1996            1995
                          ----               ----            ----
           Europe  $ 1,262,000  9.9%  $ 1,252,000 14.8%  $ 762,000 14.2%
           Japan   $ 2,880,000 22.5%  $   528,000  6.2%  $ 258,000  4.8%
</TABLE>


NOTE K.   NEW ACCOUNTING PRONOUNCEMENT
          
          In  February 1997, the Financial Accounting Standards  Board
          issued  SFAS  No.  128,  "Earnings per  Share",  superseding
          Opinion  15.   SFAS  No. 128 requires  the  calculation  and
          disclosure of Basic Earnings per Share and Diluted  Earnings
          per  Share,  effective for both interim and  annual  periods
          ending  after December 15, 1997.   Basic earnings per  share
          are  computed by dividing net income by the weighted average
          number  of  shares  of common stock outstanding  during  the
          period.  Diluted earnings per share are computed by dividing
          net  income  by  the weighted average number  of  shares  of
          common stock and common stock equivalents outstanding during
          the  period, calculated using the treasury stock  method  as
          defined  in SFAS No. 128.  In accordance with the provisions
          of  SFAS  No.  128,   the  Company is  providing  pro  forma
          disclosure  of  the  effects of this  accounting  change  on
          reported earnings per share (EPS) data as follows:
<TABLE>
<CAPTION>
<S>                                      <C>        <C>      <C>
                                           1997       1996      1995
                                           ----       ----      ----
          Primary EPS as reported         $0.29      $0.19      $0.11
          Effect of SFAS No. 128          $0.01      $0.02      $0.01
                                          -----      -----      -----
          Basic EPS as restated           $0.30      $0.21      $0.12
                                          =====      =====      =====       
                                                            
          Primary EPS as reported         $0.29      $0.19      $0.11
          Effect of SFAS No. 128             -           -          -
                                          -----      -----      -----
          Diluted EPS as restated         $0.29      $0.19      $0.11
                                          =====      =====      =====       
                                                            
                                                            
          Weighted average shares         
           outstanding for Basic EPS   13,659,927  12,255,635  12,029,908
          Common stock options and                                  
            warrants issuable under           
            treasury stock method         457,114   1,472,325     939,793
                                       ----------  ----------  ----------
          Weighted average common and                               
           common equivalent shares    
           outstanding for Diluted EPS 14,117,041  13,727,960  12,969,701 
                                       ==========  ==========  ==========
</TABLE>
                                               26
<PAGE> 28
                                   
       ITEM 8.  CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON
                  ACCOUNTING AND FINANCIAL DISCLOSURE

Not applicable.


                                   
                               PART III
                                   
        ITEM 9.  DIRECTORS, EXECUTIVE OFFICERS; COMPLIANCE WITH
                   SECTION 16(a) OF THE EXCHANGE ACT

The  following  table  sets forth certain information  concerning  the
executive officers and directors of the Company:
<TABLE>
<CAPTION>
<S> <C>                  <C>    <C>
                                 
                                                                              
            Name          Age             Position
            ----          ---             --------
     M. ("Sreeni")         48    President, Chief Executive
     Sreenivasan                 Officer and Director
     Philip L. Knutson     47    Vice President of Research
                                 and Development
     Charles B. Williams   50    Vice President of
                                 Administration and
                                 Finance, Chief Financial
                                 Officer, Secretary and
                                 Treasurer
     Jay A. Bouwens        51    Vice President of
                                 Manufacturing
     Paul C. Ahrens        45    Chairman of the Board
     Howard L. Farkas      73    Director
     Page E. Golsan, III   59    Director
                                 
</TABLE>
The  following is a brief account of the business experience  of  each
executive officer and director of the Company.

M. "Sreeni"  Sreenivasan.  Mr. Sreenivasan has served as  President
and  Chief  Executive  Officer since March 31,  1995  and  as  Chief
Operating Officer from 1990 through March 31, 1995.  Mr. Sreenivasan
has  also served as a director since 1995. From 1988 to 1990 he  was
Executive Vice President and General Manager and from 1987 to 1988 he
was  director of Manufacturing.  Previously, he worked for Ruetgers-
Nease Chemical Co. (bulk pharmaceuticals and other fine chemicals) for
13 years in various technical and manufacturing management capacities,
including 7 years as Plant Manager of their Augusta, Georgia plant.
Mr. Sreenivasan received his M.S. in Chemical Engineering from
Bucknell University and his M.B.A. from Penn State University.
                             27
<PAGE> 29                             
Philip L. Knutson, Ph.D.  Dr. Knutson has served as Vice President  of
Research and Development since 1988.   Dr. Knutson is responsible  for
process  development,  "kilo lab" production and  production  support.
From  1986 to 1988, he was a Senior Research Chemist with the Company.
Prior  thereto,  Dr.  Knutson was a Senior  Research  Chemist  at  Ash
Stevens, Inc. in Detroit, Michigan for 7 years.  He received his  B.A.
degree  from Luther College, Decorah, Iowa and his M.A. and  Ph.D.  in
Organic Chemistry from the University of Missouri - Columbia.

Charles  B.  Williams.  Mr. Williams has served as Vice  President  of
Finance  and  Administration and Treasurer since 1990.   In  1995,  he
became  the Secretary of the Company and in July 1995, he also  became
Chief  Financial Officer.  Mr. Williams is responsible for accounting,
administration, finance, personnel and information systems.  From 1988
to 1990, Mr. Williams served as the Controller.  Prior thereto, he was
Controller for White's Electronics, Inc. of Sweet Home, Oregon  for  5
years.    His   responsibilities  at  White's   Electronics   included
accounting, data processing, personnel and finance. From 1976 to 1983,
he  held several accounting and financial positions with Teledyne  Wah
Chang,  a metals producer in Albany, Oregon.  Mr. Williams earned  his
B.S. in Economics and M.B.A. from Oregon State University.

Jay  A.  Bouwens.   Mr.  Bouwens  has  served  as  Vice  President  of
Manufacturing  since  1996. From 1994 to  1996,  he  was  director  of
Manufacturing  with the Company.  From 1992 to 1994, Mr.  Bouwens  was
the  Pilot  Plant  Manager at Ash Stevens, Inc. in Detroit,  Michigan.
From  1990  to  1992  he was Production Manager for  Poly  Organix  in
Newburyport,  Massachusetts.   From  1967  to  1990  he  held  various
chemical manufacturing positions, including Process Manager for Wyeth-
Ayerst  laboratories in Rouses Point, New York.  Mr. Bouwens  received
his B.S. in Chemistry from the University of Michigan.

Paul  C. Ahrens.  Mr. Ahrens has been a director of the Company  since
its inception in 1981 and became Chairman of the Board effective March
31,  1995.   Since  1996,  he has been the founder  and  President  of
Groovie  Moovies,  Ltd.,  a film production company.   Mr.  Ahrens,  a
founder  of  the  Company,  served as President  and  Chief  Executive
Officer of Synthetech from 1989 through March 1995.  From 1981 through
1989  he  was  the Vice President of Technology.  He  also  served  as
Secretary of the Company from 1981 through 1995.  From 1979  to  1980,
Mr. Ahrens served as Vice President of Engineering of Colorado Organic
Chemical Company, an organic chemical manufacturing company located in
Commerce  City, Colorado.  Prior thereto, Mr. Ahrens spent five  years
with  Allied  Chemical  and  CIBA-Geigy  in  various  engineering  and
research  capacities.   Mr.  Ahrens holds B.S.  and  M.S.  degrees  in
Chemical Engineering from M.I.T.

Howard  L. Farkas.  Mr. Farkas has served as a director of the Company
since  1985.   Since 1981, he has been the President of Farkas  Group,
Inc.,  and since 1992 he has been President of Windsor Gardens Realty,
Inc.,  both of which are engaged in general real estate brokerage  and
management  activities.   From 1984 to 1996, he was also the  managing
director  in Manistee Gas Limited Liability Company, which is  in  the
gas  production and processing business.  Since 1986, Mr.  Farkas  has
also  served  as  Secretary and a director of Acquisition  Industries,
Inc.,  a  publicly owned acquisition and merger company.   Mr.  Farkas
serves  as  the  Chairman  of  the Board of  Logic  Devices,  Inc.,  a
Sunnyvale,  California  company specializing in  CMOS  digital  signal
process semiconductor and SRAM chips, and as a director in various natural
resource and other commercial companies.  Since May 1988, Mr. Farkas
has also been a vice president of G.A.S. Corp., which is a general
                                 28
<PAGE> 30
partner of an Oklahoma limited partnership, Gas Acquisition Services,
which filed for bankruptcy under Chapter 11.  Though not presently in
public or private practice, he has been a certified public accountant
since 1951.  Mr. Farkas received a B.S. (B.A.) from the University of
Denver.

Page  E.  Golsan,  III.  Mr. Golsan has served as a  director  of  the
Company  since  1991.   Since 1986, he has been a  principal  of  P.E.
Golsan  & Co. (formerly Golsan Management Company), a private  capital
management  firm.  From 1990 to 1992, Mr. Golsan was a senior  advisor
with Bane Barham & Holloway, registered investment advisors under  the
Investment  Advisor  Act  of 1940.  Since 1990  Mr.  Golsan  has  been
President and Chief Executive Officer of Bridgetown Capital, Inc.,  an
investment  company.   From 1987 to 1989 he  was  the  Executive  Vice
President of Calumet Industries, Inc., Chicago, Illinois (manufacturer
and  marketer of petro-chemicals and other fine chemicals).  Prior  to
1987,  he  was the President and Chief Operating Officer  of  the  K&W
Products  Division  (specialty chemical  manufacturing)  of  Berkshire
Hathaway,  Inc.  Mr.  Golsan holds an M.A. in Finance  from  Claremont
Graduate School of Business and a Doctorate in Pharmacy and a B.A.  in
Chemistry   and  Zoology,  both  from  the  University   of   Southern
California.

In  connection with the issuance of common stock and a warrant  to  JB
Partners, an investment partnership affiliated with Peter B. Cannell &
Co.  Inc.,  a  New York investment management firm, the directors  and
officers  of Synthetech (other than Mr. Golsan who was not a  director
at  the  time)  have  entered  into an agreement  to  vote  shares  of
Synthetech owned by them for the election of a nominee to the Board of
Directors  selected by JB Partners.  Unless terminated  earlier  under
certain  circumstances, this agreement will continue until  1998.   JB
Partners has advised Synthetech that it will not select a nominee  for
election at the upcoming Annual Meeting of Shareholders.

Schedule 16(a) Beneficial Ownership Reporting Compliance
- --------------------------------------------------------
Messrs.  Farkas and Golsan, each a director of the Company, failed  to
report  one and two transactions, respectively, on a timely  basis  in
compliance with Section 16(a) of the Securities Exchange Act  of  1934
("Section  16(a)").   In  addition, JB Partners,  a  10%  shareholder,
during Fiscal 1997, failed to report one transaction on a timely basis
in  compliance  with  Section  16(a).  The  Company  has  now  adopted
procedures  to  assist its directors and officers  in  complying  with
Section  16(a), which includes assisting them in preparing  the  forms
for filing.
                                  29
<PAGE> 31
                                   
                   ITEM 10.  EXECUTIVE COMPENSATION

Summary of Cash and Certain Other Compensation
- ----------------------------------------------
The  following  table provides certain summary information  concerning
compensation  paid  by  the  Company to  those  persons  who  were  at
March 31, 1997, the Company's Chief Executive Officer, the three other
executive officers of the Company and one other Company employee whose
salary  and bonus exceeded $100,000 during the last fiscal  year  (the
"Named Persons ") for the fiscal years ended March 31, 1997, 1996  and
1995:
<TABLE>
<CAPTION>
<S>            <C>    <C>       <C>       <C>          <C>

                             Summary Compensation Table
                             --------------------------
                                         Long-Term    All Other
                Annual Compensation      Compensation  Compensation($)(2)
Name and        ----------------------   ------------  ------------------    
Principal       Year   Salary    Bonus    Stock
Position        (1)    ($)       ($)      Options (#)
- --------        ----   ------    ------   -----------  ------------------
M. ("Sreeni")   1997   150,000   95,000    50,000       7,125
Sreenivasan     1996   132,000   60,000    66,000       3,203
President &     1995   113,400   28,000    52,000       4,688
Chief Executive                
Officer         
                      
Philip L.       1997   108,000   63,000    40,000       9,500
Knutson         1996    95,000   43,000    50,000       3,531
Vice President  1995    87,150   24,000    40,000       4,672
of Research and                          
Development            

Charles B.      1997    88,000   57,000    32,000       6,544
Williams        1996    75,000   35,000    34,000       3,122
Vice President  1995    67,200   20,000    25,000       3,130
of Finance and                                      
Administration

Jay A. Bouwens  1997    87,000    55,000    28,000      4,356
Vice President  1996    74,000    35,000    15,000      1,863
of              1995    34,149(3)  8,750(3)      -          -
Manufacturing                               

Mitchell A.     1997   74,250     30,000         -          -
McVay           1996   10,000(4)   1,200(4)  8,000          -
Plant Engineer         
</TABLE>
_______________________
(1)Fiscal year ended March 31.
(2)Represents  Company  contributions to  the  account  of  the  Named
   Persons under the Company's 401(k) plan.
(3)Mr. Bouwens was hired in September 1994.
(4)Mr. McVay was hired in February 1996.
                                       30
<PAGE> 32
Stock Option Grants in Last Fiscal Year
- ---------------------------------------
The  following table provides information, with respect to  the  Named
Persons,  concerning  the grant of stock options  during  fiscal  year
1997.
<TABLE>
<CAPTION>
<S><C>        <C>         <C>     <C>      <C>        <C>
                              
       Stock Options Grants in the Last Fiscal Year(1)
       -----------------------------------------------
                            % of                         
                           Total            Fair       
                 Options  Options  Exercise Market      
                 Granted  Granted     or    Value   Expiration
                   (#)       to      Base   at Date    Date
                          Employees Price      of      
                             in     ($/Sh)  Grant(3)
                           Fiscal             ($) 
  Name                     Year(2)             
- -------------   --------  -------   -----    -----    ------
M. ("Sreeni")    50,000     20%     $8.50    $8.50     May 2006
Sreenivasan                                            

Philip L.        40,000     16%     $8.50    $8.50     May 2006
Knutson                                                

Charles B.       32,000     13%     $8.50    $8.50     May 2006
Williams                                               

Jay A. Bouwens   28,000     11%     $8.50    $8.50     May 2006
                                                       
Mitchell A.           -      -          -        -            -
McVay
</TABLE>
(1)    The  Company  has  not  granted any stock  appreciation  rights
 (SARs).
(2)    Based on an aggregate of 250,000 options being granted  to  all
 employees during the fiscal year ended March 31, 1997.
(3)    The  average  of closing bid and asked prices on  the  date  of
 grant.


Stock  Option Exercises in Last Fiscal Year and Fiscal Year-End  Stock
- ----------------------------------------------------------------------
                          Option Values
                          -------------

The  following table provides information, with respect to  the  Named
Persons, concerning the options granted to them during the last fiscal
year and the options held by them at March 31, 1997.
<TABLE>
<CAPTION>
<S><C>        <C>     <C>      <C>         <C>               <C>         <C>
                                
                          Fiscal Year End Stock Option Value
                          ----------------------------------      
                 Shares                                       Value of Unexercised In-
                Acquired            Number of Unexercised       the-Money Options at       
                   on     Value      Options at Fiscal             Fiscal Year End
                Exercise Realized         Year End                       ($)(1)                    
                                 --------------------------  --------------------------
                                 Exercisable  Unexercisable  Exercisable Unexercisable
Name              (#)      ($)                 
- -----------    -------  -------- -----------   ------------  ----------  ---------      
M.("Sreeni")    61,000  $350,750   158,000     83,000        $1,205,540  $251,790       
Sreenivasan     

Philip L.       47,000  $340,750   121,240     65,000          $925,061  $190,750
Knutson             
                                       
Charles B.      29,000  $166,750    76,720     49,000          $585,374  $129,710    
Williams              

Jay A. Bouwens       -         -    10,000     33,000           $76,300   $38,150    

Mitchell A.          -         -     4,000      4,000           $20,520   $30,520
McVay  
</TABLE>
(1)    The  closing price of the Common Stock on March  31,  1997  was $7.63.
                                        31
<PAGE> 33

Compensation of Directors
- -------------------------
In  fiscal 1997, the Company established a policy to grant all current
directors  who  are not employees (other than Mr.  Ahrens,  who  is  a
founder of the Company) a nonqualified stock option for 15,000  shares
vesting  at  the  rate of 3,000 shares at the next  and  each  of  the
subsequent four annual shareholder meetings.  This option is  intended
to provide the outside director with the equivalent of an annual grant
of  3,000  shares  and  the Company does not anticipate  granting  any
additional  options  until the end of the fifth  year.   The  exercise
price  of  these options will be set at the fair market value  of  the
Common  Stock on the date of the grant.  Under this policy, in  fiscal
1997, Messrs. Golsan and Farkas each received 15,000 share options.

In  recognition  for over 11 years of service as a  director  to  the
Company  without compensation, the Company granted a cash payment  of
$20,000 and an additional nonqualified stock option for 50,000 shares
to  Mr.  Farkas.  This option vests over three years and the exercise
price  was  set  at $1.81 per share, a discount from the  $7.50  fair
market value of the Common Stock on the date of grant.

Commencing in fiscal 1998, the Company will provide directors who are
not  employees of the Company an annual fee of $4,000.   The  Company
also established a policy to grant all new directors who are not 
employees a one-time nonqualified stock  option for  10,000 shares 
which vests immediately.  Thus, new directors  who are  not  employees  
of the Company will receive  this  10,000  share option  in  addition  
to  the ongoing 15,000 share  option  described above.   Like  the  
15,000 share option, the exercise  price  of  the options  will be set 
at the fair market value of the Common Stock  on the date of grant.
                                32
<PAGE> 34
                                   
       ITEM 11.  SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS
                            AND MANAGEMENT
                                   
                   PRINCIPAL OWNERS OF COMMON STOCK


The following table sets forth the number of shares of Common Stock
and percentage of outstanding shares of Common Stock of the Company
owned as of April 1, 1997, by persons who hold of record or are known
to beneficially own 5% or more of the outstanding common stock of the
Company, each nominee and director of the Company, the named executive
officers and all officers and directors as a group.

<TABLE>
<CAPTION>
<S><C>                       <C>                         <C>
Name and Address of           Amount and                 Percent
Beneficial Owner               Nature of                   of
                              Beneficial                  Class
                               Ownership
- -------------------           ------------                ------
Paul C. Ahrens                 1,500,491(1)                 10.8%
1290 Industrial Way
Albany, OR

Michael A. Mitton                701,087                     5.1%
Suite 22
6300 Estate Frydenhoj
416-1
St. Thomas, U.S.V.I.

M. ("Sreeni")                    624,210(2)                  4.4%(3)
Sreenivasan
1290 Industrial Way
Albany, OR

Howard L. Farkas                  69,292(4)                     *
5460 South Quebec
Street
Suite 300
Englewood, CO

Page E. Golsan, III               38,000(5)                      *
3205 Canterbury Drive,
South
Salem, OR

JB Partners                    1,000,000                       7.2%
919 Third Avenue
New York, NY

Philip L. Knutson,Ph.D.          397,240(6)                    2.8%(3)
1290 Industrial Way
Albany, OR

Charles B. Williams              257,120(7)                    1.8%(3)
1290 Industrial Way
Albany, OR

Jay A. Bouwens                    29,000(8)                       *
1290 Industrial Way
Albany, OR
                                      33
<PAGE> 35

Name and Address of              Amount and                   Percent
Beneficial Owner                  Nature of                     of
                                 Beneficial                   Class
                                  Ownership

- ----------------               ------------                   --------
Mitchell A. McVay                  4,000(9)                        *
1290 Industrial Way
Albany, OR

All Officers and               2,915,353(1)(2)(4)(5)(6)(7)(8)   20.2%(3)
Directors as            
a Group (7 persons)
</TABLE>
______________________
*less than 1%.
(1)    Includes  29,000  shares of common stock  which  are  owned  of
 record  by a private foundation of which Mr. Ahrens is the President.
 Mr. Ahrens disclaims beneficial ownership of these shares.
(2)    Includes  216,000 shares of common stock which Mr.  Sreenivasan
 has  the  right  to  acquire immediately or within  sixty  (60)  days
 pursuant  to  employee  stock options.   Excludes  25,000  shares  of
 common  stock  issuable  pursuant  to  stock  options  held  by   Mr.
 Sreenivasan which are not exercisable now or within sixty (60) days.
(3)    The denominator used in calculating the percentage is equal  to
 the  number  of  shares  outstanding plus the number  of  shares  the
 beneficial  owner  (or group of beneficial owners)  has  a  right  to
 acquire  immediately  or within sixty days pursuant  to  warrants  or
 options.
(4)    Includes 19,292 shares of common stock which Mr. Farkas has the
 right  to  acquire immediately or within sixty (60) days pursuant  to
 employee  stock options.  Mr. Farkas disclaims ownership over  50,000
 shares  of  common stock held in his name which have been pledged  as
 security  for a loan and over which Mr. Farkas has no voting control.
 Excludes  45,708  shares of common stock issuable pursuant  to  stock
 options  held by Mr. Farkas which are not exercisable now  or  within
 sixty (60) days.
(5)    Excludes  15,000  shares of common stock issuable  pursuant  to
 stock  options  held by Mr. Golsan which are not exercisable  now  or
 within sixty (60) days.
(6)    Includes  166,240 shares of common stock which Dr. Knutson  has
 the  right to acquire immediately or within sixty (60) days  pursuant
 to  employee  stock options.  Excludes 20,000 shares of common  stock
 issuable pursuant to stock options held by Dr. Knutson which are  not
 exercisable now or within sixty (60) days.
(7)    Includes 109,720 shares of common stock which Mr. Williams  has
 the  right to acquire immediately or within sixty (60) days  pursuant
 to  employee  stock options.  Excludes 16,000 shares of common  stock
 issuable  pursuant  to stock options held by Mr. Williams  which  are
 not exercisable now or within sixty (60) days.
(8)    Includes  29,000 shares of common stock which Mr.  Bouwens  has
 the  right to acquire immediately or within sixty (60) days  pursuant
 to  employee  stock options.  Excludes 14,000 shares of common  stock
 issuable pursuant to stock options held by Mr. Bouwens which are  not
 exercisable now or within sixty (60) days.
(9)    Includes 4,000 shares of common stock which Mr. McVay  has  the
 right  to  acquire immediately or within sixty (60) days pursuant  to
 employee  stock  options.   Excludes 4,000  shares  of  common  stock
 issuable  pursuant to stock options held by Mr. McVay which  are  not
 exercisable now or within sixty (60) days.



                                   
       ITEM 12.  CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

In  March  1995,  Mr. Ahrens resigned his positions as  President  and
Chief  Executive  Officer of the Company and became  Chairman  of  the
Board.   At that time, Mr. Ahrens established an independent  research
and  development effort to investigate new applications of novel amino
acids  and peptides.  In connection with this transition, the  Company
and Mr. Ahrens entered into an agreement (the "Agreement") pursuant to
which  Mr. Ahrens agreed to provide consulting services to the Company
and to provide the Company with licensing rights for any invention  he
                                34
<PAGE> 36

might  develop  during  the  year which involved  amino  acids  and/or
peptide-based materials (the "Amino Acid Technology"). In March  1996,
at  the  conclusion  of the consulting services and  research  period,
Mr.  Ahrens  advised  the Company that he did not intend  to  continue
further laboratory research.  At that time, the Company requested, and
Mr. Ahrens agreed to, an Addendum to the Agreement to expand the
Company's licensing rights to any Amino Acid Technology that he may
discover at any time in the future.  The Company also agreed to
reimburse Mr. Ahrens for his expenses associated with his attendance
on behalf of the Company at technical research symposiums.

Certain  directors and officers of the Company have  entered  into  an
agreement to vote shares of Synthetech Common Stock owned by them  for
the  election  of a nominee to the Board of Directors selected  by  JB
Partners, an investor in the Company.  See Item 9.
                                   
              ITEM 13.  EXHIBITS AND REPORTS ON FORM 8-K

(a)   Exhibits.   The following documents are filed as  part  of  this
Annual Report on Form 10-KSB:

3(i)(1)   Articles of Incorporation of Synthetech, Inc., as amended

3(ii)     Bylaws of Synthetech, Inc., as amended

10.1(2),(3) License  Agreement  dated March 16, 1990  between  Synthetech,
        Inc. and Miwon Co. Ltd.

10.2(2),(4) Supply  Agreement  dated January 3, 1989  between  Synthetech,
        Inc. and Biomeasure, Incorporated

10.3(2),(4) License  Agreement  dated January 3, 1989 between  Synthetech,
        Inc. and Biomeasure, Incorporated

10.4(2)+  Synthetech,  Inc. Amended and Restated 1984 Stock  Option  and
        Bonus Plan

10.5(5)+  Synthetech, Inc. 1990 Stock Option Plan

10.6(8)   Amendment  No.  1  to  Stock  and Warrant  Purchase  Agreement
        between the Company and JB dated as of March 26, 1996

10.7(6)   Agreement  dated September 30, 1991 Among Certain Shareholders
        of the Company

10.8(7)   Agreement  and  Release  dated as of March  31,  1995  between
        Synthetech, Inc. and Paul C. Ahrens (the "Ahrens Agreement")

10.9(8)   Addendum to Ahrens Agreement dated as of April 1, 1996
                                     35
<PAGE> 37

10.10   1995 Incentive Compensation Plan, as amended

10.11   Promissory Note dated September 8, 1995 from Synthetech,  Inc.
        to United States National Bank of Oregon.

10.12   Commercial Security Agreement dated September 8, 1995  between
        Synthetech, Inc. and United States National Bank of Oregon

10.13   Change  in  Terms Agreement dated September 12,  1996  between
        Synthetech, Inc. and United States National Bank of Oregon

10.14   Nonqualified  Stock  Option dated as of November  7,  1996  to
        purchase  50,000 shares of Common Stock issued  to  Howard  L.
        Farkas.

10.15   Nonqualified  Stock  Option dated as of November  7,  1996  to
        purchase  15,000 shares of Common Stock issued  to  Howard  L.
        Farkas.

10.16   Nonqualified  Stock  Option dated as of November  7,  1996  to
        purchase  15,000  shares of Common Stock  issued  to  Page  E.
        Golsan III.

10.17   Synthetech,  Inc. Purchase Order dated June 17, 1996  to  R.L.
        Reimers Construction in the amount of $250,000.

10.18   Synthetech,  Inc.  Purchase Order dated  August  23,  1996  to
        CE/Western in the amount of $240,000.

10.19   Synthetech,  Inc. Purchase Order dated September  4,  1996  to
        R.L. Reimers Construction in the amount of $189,000.

10.20   Synthetech, Inc. Purchase Order dated November 7, 1996 to R.L.
        Reimers Construction in the amount of $1,870,700.

10.21   Synthetech,  Inc. Purchase Order dated February  20,  1997  to
        Olsson Industrial Electric in the amount of $335,864.

10.22   Synthetech,  Inc. Purchase Order dated May 2, 1997  to  Oregon
        Industrial Contractors, Inc. in the amount of $626,276.

23      Consent of Arthur Andersen LLP

__________________________

+ Management contract or compensatory plan.

(1)  Incorporated  by reference to the exhibits filed with  registrant's
Annual Report on Form 10-K for the fiscal year ended March 31, 1991.
                                  36
<PAGE> 38
(2)  Incorporated  by reference to the exhibits filed with  registrant's
Annual Report on Form 10-K for the fiscal year ended March 31, 1990.

(3)  Confidential  treatment of certain portions of  this  document  was
granted by the Commission on May 7, 1990 (File No. 33-27566).

(4)  Confidential  treatment of certain portions of  this  document  was
granted by the Commission on January 10, 1990 (File No. 33-27566).

(5)  Incorporated  by reference to Exhibit A to the definitive  copy  of
registrant's  Proxy Statement (dated October 23, 1990)  for  the  1990
Annual Meeting of Shareholders.

(6)  Incorporated  by reference to the exhibits filed with  registrant's
Annual Report on Form 10-K for the fiscal year ended March 31, 1992.

(7)  Incorporated  by reference to the exhibits filed with  registrant's
Annual Report on Form 10-KSB for the fiscal year ended March 31, 1995.

(8)  Incorporated  by reference to the exhibits filed with  registrant's
Annual Report on Form 10-KSB for the fiscal year ended March 31, 1996.



(b)  Reports on Form 8-K

None.
                                     37
<PAGE> 39
                              SIGNATURES

In  accordance  with  Section 13 or 15(d) of  the  Exchange  Act,  the
registrant has duly caused this report to be signed on its  behalf  by
the undersigned, thereunto duly authorized.
                               
Date:  June 18, 1997           SYNTHETECH, INC.
                               (Registrant)
                               
                               
                               By  /s/  M. Sreenivasan
                                  M. ("Sreeni") Sreenivasan
                                  President and Chief
                                  Executive Officer

In accordance with the Exchange Act, this report has been signed below
by  the  following  persons on behalf of the  registrant  and  in  the
capacities and on the dates indicated.

     Signature                Title                  Date
                                                       
/s/  M. Sreenivasan President, Chief            June 18, 1997
   M. ("Sreeni")    Executive Officer
    Sreenivasan     (Principal Executive
                    Officer) and Director
                                                       
  /s/  Charles B.   Vice President of Finance   June 18, 1997
     Williams       and Administration, Chief
Charles B. Williams Financial Officer,
                    Secretary and Treasurer
                    (Principal Financial
                    Officer and Principal
                    Accounting Officer)
                                                       
/s/  Paul C. Ahrens Chairman of the Board       June 18, 1997
  Paul C. Ahrens
                                                       
                                                June 18, 1997
  /s/  Howard L.    Director
      Farkas
 Howard L. Farkas
                                                       
                                                June 18, 1997
   /s/  Page E.     Director
    Golsan, III
Page E. Golsan, III
                                  38
<PAGE> 40


                           INDEX TO EXHIBITS
                                                          Sequential Page No.

3(i)(1)1   Articles of Incorporation of Synthetech,  Inc.,
        as amended

3(ii)   Bylaws of Synthetech, Inc., as amended                      42

10.1(2),(3) License  Agreement dated March 16, 1990 between
        Synthetech, Inc. and Miwon Co. Ltd.

10.2(2),(4) Supply  Agreement dated January 3, 1989 between
        Synthetech, Inc. and Biomeasure, Incorporated

10.3(2),(4) License Agreement dated January 3, 1989 between
        Synthetech, Inc. and Biomeasure, Incorporated

10.4(2)+  Synthetech,  Inc.  Amended  and  Restated  1984
        Stock Option and Bonus Plan

10.5(5)+  Synthetech, Inc. 1990 Stock Option Plan

10.6(8)   Amendment  No. 1 to Stock and Warrant  Purchase
        Agreement between the Company and JB  dated  as
        of March 26, 1996

10.7(6)   Agreement   dated  September  30,  1991   Among
        Certain Shareholders of the Company

10.8(7)   Agreement  and Release dated as  of  March  31,
        1995  between  Synthetech,  Inc.  and  Paul  C.
        Ahrens (the "Ahrens Agreement")

10.9(8)   Addendum  to  Ahrens  Agreement  dated  as   of
        April 1, 1996

10.10   1995 Incentive Compensation Plan, as amended                72

10.11   Promissory  Note dated September 8,  1995  from
        Synthetech, Inc. to United States National Bank
        of Oregon.                                                  89
10.12   Commercial  Security Agreement dated  September
        8,  1995  between Synthetech, Inc.  and  United
        States National Bank of Oregon                              93

10.13   Change  in Terms Agreement dated September  12,
        1996 between Synthetech, Inc. and United States
        National Bank of Oregon                                    102

10.14   Nonqualified Stock Option dated as of  November
        7,  1996  to purchase 50,000 shares  of  Common
        Stock issued to Howard L. Farkas                          107

10.15   Nonqualified Stock Option dated as of  November
        7,  1996  to purchase 15,000 shares  of  Common
        Stock issued to Howard L. Farkas                          110
                                     39
<PAGE> 41

10.16   Nonqualified Stock Option dated as of  November
        7,  1996  to purchase 15,000 shares  of  Common
        Stock issued to Page E. Golsan III                        113

10.17   Synthetech, Inc. Purchase Order dated June  17,
        1996 to R.L. Reimers Construction in the amount
        of $250,000                                               116

10.18   Synthetech,  Inc. Purchase Order  dated  August
        23,  1996  to  CE/Western  in  the  amount   of
        $240,000                                                  119

10.19   Synthetech, Inc. Purchase Order dated September
        4,  1996  to R.L. Reimers Construction  in  the
        amount of $189,000                                        125

10.20   Synthetech, Inc. Purchase Order dated  November
        7,  1996  to R.L. Reimers Construction  in  the
        amount of $1,870,700                                      127

10.21   Synthetech, Inc. Purchase Order dated  February
        20,  1997 to Olsson Industrial Electric in  the
        amount of $335,864                                        129
10.22   Synthetech,  Inc. Purchase Order dated  May  2,
        1997 to Oregon Industrial Contractors, Inc.  in
        the amount of $626,276                                    130

23      Consent of Arthur Andersen LLP                            131
__________________________

+ Management contract or compensatory plan.

(1)  Incorporated  by reference to the exhibits filed with  registrant's
Annual Report on Form 10-K for the fiscal year ended March 31, 1991.

(2)  Incorporated  by reference to the exhibits filed with  registrant's
Annual Report on Form 10-K for the fiscal year ended March 31, 1990.

(3)  Confidential  treatment of certain portions of  this  document  was
granted by the Commission on May 7, 1990 (File No. 33-27566).

(4)  Confidential  treatment of certain portions of  this  document  was
granted by the Commission on January 10, 1990 (File No. 33-27566).

(5)  Incorporated  by reference to Exhibit A to the definitive  copy  of
registrant's  Proxy Statement (dated October 23, 1990)  for  the  1990
Annual Meeting of Shareholders.

(6)  Incorporated  by reference to the exhibits filed with  registrant's
Annual Report on Form 10-K for the fiscal year ended March 31, 1992.

(7)  Incorporated  by reference to the exhibits filed with  registrant's
Annual Report on Form 10-KSB for the fiscal year ended March 31, 1995.

(8) Incorporated by reference to the exhibits filed with registrant's
Annual Report on Form 10-KSB for the fiscal year ended March 31, 1996.
                                40


<PAGE> 42                                                         Exhibit 3(ii)
                                                         of Form 10KSB
                                                                      
                                                                      
                                   
                                BYLAWS
                                   
                                  OF
                                   
                           SYNTHETECH, INC.
                                   
                              AMENDMENTS








                                  
<PAGE> 43                                   
                                   
     
          Date of
     
     Section        Effect of Amendment      Amendment
                                                  
2.1          Changed date of annual meeting of    June 10, 1994
             shareholders and deleted mechanics   (Board)
             of setting annual meeting date
                                                  
3.2          Changed number, tenure and           June 6, 1997
             qualifications section               (Board)
     
                                i                                         
<PAGE> 44                                   
                               CONTENTS

SECTION 1. OFFICES                                        1

SECTION 2. SHAREHOLDERS                                   1
     
     2.1   Annual Meeting                                 1
     
     2.2   Special Meetings                               1
     
     2.3   Place of Meeting                               1
     
     2.4   Notice of Meeting                              2
     
     2.5   Waiver of Notice                               2
     
     2.6   Fixing of Record Date for Determining
           Shareholders                                   2
     
     2.7   Shareholders' List                             3
     
     2.8   Quorum                                         3
     
     2.9   Manner of Acting                               4
     
     2.10  Proxies                                        4
     
     2.11  Voting of Shares                               4
     
     2.12  Voting for Directors                           4
     
     2.13  Action by Shareholders Without a Meeting       5
     
     2.14  Voting of Shares by Corporations               5
           
           2.14.1  Shares Held by Another Corporation     5
           
           2.14.2  Shares Held by the Corporation         5
     
     2.15  Acceptance or Rejection of Shareholder Votes,
           Consents, Waivers and Proxy Appointments       5
           
           2.15.1  Documents Bearing Name of Shareholders       5
           
           2.15.2  Documents Bearing Name of Third Parties 6
                                ii
<PAGE> 45           
           2.15.3  Rejection of Documents                 6

SECTION 3. BOARD OF DIRECTORS                             6
     
     3.1   General Powers                                 6
     
     3.2   Number, Tenure and Qualifications              7
     
     3.3   Annual and Regular Meetings                    7
     
     3.4   Special Meetings                               7
     
     3.5   Meetings by Telecommunications                 7
     
     3.6   Notice of Special Meetings                     8
           
           3.6.1   Personal Delivery                      8
           
           3.6.2   Delivery by Mail                       8
           
           3.6.3   Delivery by Telegraph                  8
           
           3.6.4   Oral Notice                            8
           
           3.6.5   Notice by Facsimile Transmission       8
           
           3.6.6   Notice by Private Courier              9
     
     3.7   Waiver of Notice                               9
           
           3.7.1   Written Waiver                         9
           
           3.7.2   Waiver by Attendance                   9
     
     3.8   Quorum                                         9
     
     3.9   Manner of Acting                               9
     
     3.10  Presumption of Assent                          9
     
     3.11  Action by Board or Committees Without a Meeting  10
     
     3.12  Resignation                                   10
     
     3.13  Removal                                       10
                                iii
<PAGE> 46     
     3.14  Vacancies                                     10
     
     3.15  Minutes                                       11
     
     3.16  Executive and Other Committees                11
           
           3.16.1  Creation of Committees                11
           
           3.16.2  Authority of Committees               11
           
           3.16.3  Quorum and Manner of Acting           12
           
           3.16.4  Minutes of Meetings                   12
           
           3.16.5  Resignation                           12
           
           3.16.6  Removal                               12
     
     3.17  Compensation                                  12

SECTION 4. OFFICERS                                      13
     
     4.1   Number                                        13
     
     4.2   Appointment and Term of Office                13
     
     4.3   Resignation                                   13
     
     4.4   Removal                                       13
     
     4.5   Vacancies                                     14
     
     4.6   Chair of the Board                            14
     
     4.7   President                                     14
     
     4.8   Vice President                                14
     
     4.9   Secretary                                     15
     
     4.10  Treasurer                                     15
     
     4.11  Salaries                                      15
                                iv
<PAGE> 47

SECTION 5. CONTRACTS, LOANS, CHECKS AND DEPOSITS         15
     
     5.1   Contracts                                     15
     
     5.2   Loans to the Corporation                      16
     
     5.3   Loans to Directors                            16
     
     5.4   Checks, Drafts, Etc.                          16
     
     5.5   Deposits                                      16

SECTION 6. CERTIFICATES FOR SHARES AND THEIR TRANSFER    16
     
     6.1   Issuance of Shares                            16
     
     6.2   Escrow for Shares                             17
     
     6.3   Certificates for Shares                       17
     
     6.4   Stock Records                                 17
     
     6.5   Restriction on Transfer                       17
           
           6.5.1   Securities Laws                       17
           
           6.5.2   Other Restrictions                    18
     
     6.6   Transfer of Shares                            18
     
     6.7   Lost or Destroyed Certificates                18
     
     6.8   Transfer Agent and Registrar                  18
     
     6.9   Officer Ceasing to Act                        18
     
     6.10  Fractional Shares                             18
                                  v
<PAGE> 48

SECTION 7. BOOKS AND RECORDS                             19

SECTION 8. FISCAL YEAR                                   19

SECTION 9. SEAL                                          19

SECTION 10.INDEMNIFICATION                               19
     
     10.1  Directors and Officers                        19
     
     10.2  Officers, Employees and Other Agents          19
     
     10.3  No Presumption of Bad Faith                   19
     
     10.4  Advances of Expenses                          19
     
     10.5  Enforcement                                   20
     
     10.6  Nonexclusivity of Rights                      21
     
     10.7  Survival of Rights                            21
     
     10.8  Insurance                                     21
     
     10.9  Amendments to Law                             21
     
     10.10 Savings Clause                                21
     
     10.11 Certain Definitions                           21

SECTION 11.AMENDMENTS                                    22

SECTION 12.CONTROL SHARE ACQUISITION STATUTE             23
                            vi     
<PAGE> 49     
                                   
                                BYLAWS
                                  OF
                           SYNTHETECH, INC.
     
     

SECTION 1.  OFFICES
     
     The principal office of the Corporation shall be located at the
principal place of business or such other place as the Board of
Directors (the "Board") may designate.  The Corporation may have such
other offices, either within or without the State of Oregon, as the
Board may designate or as the business of the Corporation may require
from time to time.

SECTION 2.  SHAREHOLDERS
     
     2.1   Annual Meeting
     
     The annual meeting of the shareholders shall be held the 15th day
of July in each year, or on such other day as shall be fixed by
resolution of the Board, at the principal office of the Corporation or
such other place as fixed by the Board, for the purpose of electing
Directors and transaction such other business as may properly come
before the meeting.  If the day fixed for the annual meeting is a
legal holiday at the place of the meeting, the meeting shall be held
on the next succeeding business day.
     
     2.2   Special Meetings
     
     The Board, the President or the Chair of the Board may call
special meetings of the shareholders for any purpose.  The holders of
not less than one-tenth of all the outstanding shares of the
Corporation entitled to vote on any issue proposed to be considered at
the proposed special meeting, if they date, sign and deliver to the
Corporation's Secretary a written demand for a special meeting
describing the purpose(s) for which it is to be held, may call a
special meeting of the shareholders for such stated purpose.
     
     2.3   Place of Meeting
     
     All meetings shall be held at the principal office of the
Corporation or at such other place as designated by the Board, by any
persons entitled to call a meeting hereunder, or in a waiver of notice
signed by all of the shareholders entitled to vote at the meeting.
                                1
<PAGE> 50     
     2.4   Notice of Meeting
     
          2.4.1  The Corporation shall cause to be delivered to each
shareholder entitled to notice of or to vote at an annual or special
meeting of shareholders, either personally or by mail, not less than
ten (10) nor more than sixty (60) days before the meeting, written
notice stating the date, time and place of the meeting and, in the
case of a special meeting, the purpose(s) for which the meeting is
called.
     
          2.4.2  Notice to a shareholder of an annual or special
shareholder meeting shall be in writing.  Such notice, if in
comprehensible form, is effective (a) when mailed, if it is mailed
postpaid and is correctly addressed to the shareholder's address shown
in the Corporation's current record of shareholders; or (b) when
received by the shareholder, if it is delivered by telegraph,
facsimile transmission or private courier.
     
          2.4.3  If an annual or special shareholders' meeting is
adjourned to a different date, time or place, notice need not be given
of the new date, time or place if the new date, time or place is
announced at the meeting before adjournment, unless a new record date
for the adjourned meeting is or must be fixed under Section 2.6.1 of
these bylaws or the Oregon Business Corporation Act.
     
     2.5   Waiver of Notice
     
          2.5.1  Whenever any notice is required to be given to any
shareholder under the provisions of these Bylaws, the Articles of
Incorporation or the Oregon Business Corporation Act, a waiver thereof
in writing, signed by the person or persons entitled to such notice,
whether before or after the time stated therein, and delivered to the
Corporation for inclusion in the minutes for filing with the corporate
records, shall be deemed equivalent to the giving of such notice.
     
          2.5.2  The attendance of a shareholder at a meeting waives
objection to lack of, or defect in, notice of such meeting or of
consideration of a particular matter at the meeting, unless the
shareholder, at the beginning of the meeting or prior to consideration
of such matter, objects to holding the meeting, transacting business
at the meeting, or considering the matter when presented at the
meeting.
     
     2.6   Fixing of Record Date for Determining Shareholders
     
          2.6.1  For the purpose of determining shareholders entitled
to notice of, or to vote at, any meeting of shareholders or any
adjournment thereof, or shareholders entitled to receive payment of
any dividend, or in order to make a determination of shareholders for
any other purpose, the Board may fix in advance a date as the record
date for any such determination.  Such record date shall be not more
than seventy (70) days, and in case of a meeting of shareholders, not
                                 2
<PAGE> 51
less than ten (10) days, prior to the date on which the particular
action requiring such determination is to be taken.  If no record date
is fixed for the determination of shareholders entitled to notice of
or to vote at a meeting, or to receive payment of a dividend, the date
on which the notice of meeting is mailed or on which the resolution of
the Board declaring such dividend is adopted, as the case may be,
shall be the record date for such determination.  Such determination
shall apply to any adjournment of the meeting, provided such
adjournment is not set for a date more than 120 days after the date
fixed for the original meeting.
     
          2.6.2  The record date for the determination of shareholders
entitled to demand a special shareholder meeting shall be the date the
first shareholder signs the demand.
     
     2.7   Shareholders' List
     
          2.7.1  Beginning two (2) business days after notice of a
meeting of shareholders is given, a complete alphabetical list of the
shareholders entitled to notice of such meeting shall be made,
arranged by voting group, and within each voting group by class or
series, with the address of and number of shares held by each
shareholder.  This record shall be kept on file at the Corporation's
principal office or at a place identified in the meeting notice in the
city where the meeting will be held.  On written demand, this record
shall be subject to inspection by any shareholder at any time during
normal business hours.  Such record shall also be kept open at such
meeting for inspection by any shareholder.
     
          2.7.2  A shareholder may, on written demand, copy the
shareholders' list at such shareholder's expense during regular
business hours, provided that:
     
          a.   Such shareholder's demand is made in good faith and for
a proper purpose;
     
          b.   Such shareholder has described with reasonable
particularity his/her/its purpose in the written demand; and
     
          c.   The shareholders' list is directly connected with such
shareholder's purpose.
     
     2.8   Quorum
     
     A majority of the votes entitled to be cast on a matter at a
meeting by a voting group, represented in person or by proxy, shall
constitute a quorum of that voting group for action on that matter at
a meeting of the shareholders.  If a quorum is not present for a
                                 3
<PAGE> 52
matter to be acted upon, a majority of the shares represented at the
meeting may adjourn the meeting from time to time without further
notice.  If the necessary quorum is present or represented at a
reconvened meeting following such an adjournment, any business may be
transacted that might have been transacted at the meeting as
originally called.  The shareholders present at a duly organized
meeting may continue to transact business until adjournment,
notwithstanding the withdrawal of enough shareholders to leave less
than a quorum.
     
     2.9   Manner of Acting
     
          2.9.1  If a quorum exists, action on a matter (other than
the election of Directors) by a voting group is approved if the votes
cast within the voting group favoring the action exceed the votes cast
opposing the action, unless the affirmative vote of a greater number
is required by these Bylaws, the Articles of Incorporation or the
Oregon Business Corporation Act.
     
          2.9.2  If a matter is to be voted on by a single group,
action on that matter is taken when voted upon by that voting group.
If a matter is to be voted on by two or more voting groups, action on
that matter is taken only when voted upon by each of those voting
groups counted separately.  Action may be taken by one voting group on
a matter even though no action is taken by another voting group
entitled to vote on such matter.
     
     2.10  Proxies
     
     A shareholder may vote by proxy executed in writing by the
shareholder or by his or her attorney-in-fact.  Such proxy shall be
effective when received by the Secretary or other officer or agent
authorized to tabulate votes at the meeting.  A proxy shall become
invalid eleven (11) months after the date of its execution, unless
otherwise expressly provided in the proxy.  A proxy for a specified
meeting shall entitle the holder thereof to vote at any adjournment of
such meeting but shall not be valid after the final adjournment
thereof.
     
     2.11  Voting of Shares
     
     Each outstanding share entitled to vote shall be entitled to one
vote upon each matter submitted to a vote at a meeting of
shareholders.
     
     2.12  Voting for Directors
     
     Each shareholder may vote, in person or by proxy, the number of
shares owned by such shareholder that are entitled to vote at an
election of Directors, for as many persons as there are Directors to
be elected and for whose election such shares have a right to vote.
                                  4
<PAGE> 53
Unless otherwise provided in the Articles of Incorporation, Directors
are elected by a plurality of the votes cast by shares entitled to
vote in the election at a meeting at which a quorum is present.
     
     2.13  Action by Shareholders Without a Meeting
     
     Any action which could be taken at a meeting of the shareholders
may be taken without a meeting if a written consent setting forth the
action so taken is signed by all shareholders entitled to vote with
respect to the subject matter thereof.  The action shall be effective
on the date on which the last signature is placed on the consent, or
at such earlier or later time as is set forth therein.  Such written
consent, which shall have the same force and effect as a unanimous
vote of the shareholders, shall be inserted in the minute book as if
it were the minutes of a meeting of the shareholders.
     
     2.14  Voting of Shares by Corporations
           
           2.14.1  Shares Held by Another Corporation
     
     Shares standing in the name of another corporation may be voted
by such officer, agent or proxy as the bylaws of such other
corporation may prescribe, or, in the absence of such provision, as
the board of directors of such corporation may determine; provided,
however, such shares are not entitled to vote if the Corporation owns,
directly or indirectly, a majority of the shares entitled to vote for
directors of such other corporation.
           
           2.14.2  Shares Held by the Corporation
     
     Authorized but unissued shares shall not be voted or counted for
determining whether a quorum exists at any meeting or counted in
determining the total number of outstanding shares at any given time.
Notwithstanding the foregoing, shares of its own stock held by the
Corporation in a fiduciary capacity may be counted for purposes of
determining whether a quorum exists, and may be voted by the
Corporation.
     
     2.15  Acceptance or Rejection of Shareholder Votes, Consents,
           Waivers and Proxy Appointments
           
           2.15.1  Documents Bearing Name of Shareholders
     
     If the name signed on a vote, consent, waiver or proxy
appointment corresponds to the name of a shareholder, the Secretary or
other agent authorized to tabulate votes at the meeting may, if acting
in good faith, accept such vote, consent, waiver or proxy appointment
and give it effect as the act of the shareholder.
                                 5
<PAGE> 54
           2.15.2  Documents Bearing Name of Third Parties
     
     If the name signed on a vote, consent, waiver or proxy
appointment does not correspond to the name of its shareholder, the
Secretary or other agent authorized to tabulate votes at the meeting
may nevertheless, if acting in good faith, accept such vote, consent,
waiver or proxy appointment and give it effect as the act of the
shareholder if:
     
          a.   The shareholder is an entity and the name signed
purports to be that of an officer or an agent of the entity;
     
          b.   The name signed purports to be that of an
administrator, executor, guardian or conservator representing the
shareholder and, if the Secretary or other agent requests, acceptable
evidence of fiduciary status has been presented;
     
          c.   The name signed purports to be that of a receiver or
trustee in bankruptcy of the shareholder, and, if the Secretary or
other agent requests, acceptable evidence of this status has been
presented;
     
          d.   The name signed purports to be that of a pledgee,
beneficial owner or attorney-in-fact of the shareholder and, if the
Secretary or other agent requests, acceptable evidence of the
signatory's authority to sign has been presented; or
     
          e.   Two or more persons are the shareholder as cotenants or
fiduciaries and the name signed purports to be the name of at least
one of the co-owners and the person signing appears to be acting on
behalf of all co-owners.
           
           2.15.3  Rejection of Documents
     
     The Secretary or other agent authorized to tabulate votes at the
meeting is entitled to reject a vote, consent, waiver or proxy
appointment if such agent, acting in good faith, has reasonable basis
for doubt about the validity of the signature on it or about the
signatory's authority to sign for the shareholder.

SECTION 3.  BOARD OF DIRECTORS
     
     3.1   General Powers
     
     The business and affairs of the Corporation shall be managed by
the Board, except as may be otherwise provided in these Bylaws, the
Articles of Incorporation or the Oregon Business Corporation Act.
                                   6
<PAGE> 55
     3.2   Number, Tenure and Qualifications
     
     The Board shall consist of no less than three (3) and no more
than seven (7) Directors, the specific number to be set by resolution
of the Board.  The number of Directors may be changed from time to
time by amendment to these Bylaws, but no decrease in the number of
Directors shall shorten the term of any incumbent Director.  The Board
shall be divided into three classes, with each class to contain at
least two members and to be as nearly equal in number as possible, but
no decrease in the number of such classes shall the effect of
shortening the term of any incumbent Director.  At the 1997 annual
meeting of shareholders, the Directors of Class 1 shall be elected for
a term expiring at the 1998 annual meeting of shareholders, and the
Directors of Class 2 shall be elected for a term expiring at the 1999
annual meeting of shareholders and the Directors of Class 3 shall be
elected for a term expiring at the 2000 annual meeting of
shareholders.  Commencing in 1998, and at each annual meeting of
shareholders thereafter, the successors to the class of Directors
whose terms expire at that meeting shall be elected to hold office for
a term of three (3) years, and each Director shall serve for the term
he or she was elected or until his or her successor shall have been
elected and qualified or until his or her death, resignation, or
removal from office.  Directors need not be shareholders of the
corporation or residents of the State of Oregon.
     
     3.3   Annual and Regular Meetings
     
     An annual Board meeting shall be held without further notice
immediately after and at the same place as the annual meeting of
shareholders.
     
     By resolution the Board, or any committee thereof, may specify
the time and place for holding regular meetings thereof without other
notice than such resolution.
     
     3.4   Special Meetings
     
     Special meetings of the Board or any committee designated by the
Board may be called by or at the request of the President or any
member of the Board of Directors and, in the case of any special
meeting of any committee designated by the Board, or by the Chair
thereof.  The person or persons authorized to call special meetings
may fix any place either within or without the State of Oregon as the
place for holding any special Board or committee meeting called by
them.
     
     3.5   Meetings by Telecommunications
     
     Members of the Board or any committee designated by the Board may
participate in a meeting of such Board or committee by use of any
means of communication by which all persons participating may
                               7
<PAGE> 56

simultaneously hear each other during the meeting.  Participation by
such means shall be deemed presence in person at the meeting.
     
     3.6   Notice of Special Meetings
     
     Notice of a special Board or committee meeting stating the date,
time and place of the meeting shall be given to a Director in writing
or orally by telephone or in person as set forth below.  Neither the
business to be transacted at, nor the purpose of, any special meeting
need be specified in the notice of such meeting.
           
           3.6.1   Personal Delivery
     
     If delivery is by personal service, the notice shall be effective
if delivered at such address at least one day before the meeting.
           
           3.6.2   Delivery by Mail
     
     If notice is delivered by mail, the notice shall be deemed
effective if deposited in the official government mail at least five
days before the meeting properly addressed to a Director at his or her
address shown on the records of the Corporation with postage prepaid.
           
           3.6.3   Delivery by Telegraph
     
     If notice is delivered by telegraph, the notice shall be deemed
effective if the content thereof is delivered to the telegraph company
by such time that the telegraph company guarantees delivery at least
one day before the meeting.
           
           3.6.4   Oral Notice
     
     If notice is delivered orally, by telephone or in person, the
notice shall be effective if personally given to a Director at least
one day before the meeting.
           
           3.6.5   Notice by Facsimile Transmission
     
     If notice is delivered by facsimile transmission, the notice
shall be deemed effective if the content thereof is transmitted to the
office of a Director, at the facsimile number shown on the records of
the Corporation, at least one day before the meeting, and receipt is
either confirmed by confirming transmission equipment or acknowledged
by the receiving office.
                                  8
<PAGE> 57     
      
           3.6.6   Notice by Private Courier
     
     If notice is delivered by private courier, the notice shall be
deemed effective if delivered to the courier, properly addressed and
prepaid, by such time that the courier guarantees delivery at least
one day before the meeting.
     
     3.7   Waiver of Notice
           
           3.7.1   Written Waiver
     
     Whenever any notice is required to be given to any Director under
the provisions of these Bylaws, the Articles of Incorporation or the
Oregon Business Corporation Act, a waiver thereof in writing, executed
at any time, specifying the meeting for which notice is waived, signed
by the person or persons entitled to such notice, and filed with the
minutes or corporate records, shall be deemed equivalent to the giving
of such notice.
           
           3.7.2   Waiver by Attendance
     
     The attendance of a Director at a Board or committee meeting
shall constitute a waiver of notice of such meeting, unless the
Director, at the beginning of the meeting, or promptly upon such
Director's arrival, objects to holding the meeting or transacting any
business thereat and does not thereafter vote for or assent to action
taken at the meeting.
     
     3.8   Quorum
     
     A majority of the number of Directors fixed by or in the manner
provided by these Bylaws shall constitute a quorum for the transaction
of business at any Board meeting.
     
     3.9   Manner of Acting
     
     The act of the majority of the Directors present at a Board or
committee meeting at which there is a quorum shall be the act of the
Board or committee, unless the vote of a greater number is required by
these Bylaws, the Articles of Incorporation or the Oregon Business
Corporation Act.
     
     3.10  Presumption of Assent
     
     A Director of the Corporation present at a Board or committee
meeting at which action on any corporate matter is taken shall be
deemed to have assented to the action taken unless such Director
objects at the beginning of the meeting, or promptly upon such
Director's arrival, to holding the meeting or transacting business at
                                   9
<PAGE> 58

the meeting; or such Director's dissent is entered in the minutes of
the meeting; or such Director delivers a written notice of dissent or
abstention to such action with the presiding officer of the meeting
before the adjournment thereof; or such Director forwards such notice
by registered mail to the Secretary of the Corporation immediately
after the adjournment of the meeting.  A Director who voted in favor
of such action may not thereafter dissent or abstain.
     
     3.11  Action by Board or Committees Without a Meeting
     
     Any action which could be taken at a meeting of the Board or of
any committee appointed by the Board may be taken without a meeting if
a written consent setting forth the action so taken is signed by each
Director or by each committee member.  The action shall be effective
when the last signature is placed on the consent, unless the consent
specifies an earlier or later date.  Such written consent, which shall
have the same effect as a unanimous vote of the Directors or such
committee, shall be inserted in the minute book as if it were the
minutes of a Board or committee meeting.
     
     3.12  Resignation
     
     Any Director may resign at any time by delivering written notice
to the Chair of the Board, the Board, or to the registered office of
the Corporation.  Such resignation shall take effect at the time
specified in the notice, or if no time is specified, upon delivery.
Unless otherwise specified therein, the acceptance of such resignation
shall not be necessary to make it effective.  Once delivered, a notice
of resignation is irrevocable unless revocation is permitted by the
Board.
     
     3.13  Removal
     
     One or more members of the Board (including the entire Board) may
be removed at a meeting of shareholders called expressly for that
purpose, provided that the notice of such meeting states that the
purpose, or one of the purposes, of the meeting is such removal.  A
member of the Board may be removed with or without cause, unless the
Articles of Incorporation permit removal for cause only, by a vote of
the holders of a majority of the shares then entitled to vote on the
election of the Director(s).  A Director may be removed only if the
number of votes cast to remove the Director exceeds the number of
votes cast to not remove the Director.  If a Director is elected by a
voting group of shareholders, only the shareholders of that voting
group may participate in the vote to remove such Director.
     
     3.14  Vacancies
     
     Any vacancy occurring on the Board, including a vacancy resulting
from an increase in the number of Directors, may be filled by the
                                10
<PAGE> 59

shareholders, by the Board, by the affirmative vote of a majority of
the remaining Directors though less than a quorum of the Board, or by
a sole remaining Director.  A Director elected to fill a vacancy shall
be elected for the unexpired term of his or her predecessor in office;
except that the term of a Director elected by the Board to fill a
vacancy expires at the next shareholders' meeting at which Directors
are elected.  Any Directorship to be filled by reason of an increase
in the number of Directors may be filled by the affirmative vote of a
majority of the number of Directors fixed by the Bylaws prior to such
increase for a term of office continuing only until the next election
of Directors by the shareholders.  Any Directorship not so filled by
the Directors shall be filled by election at the next annual meeting
of shareholders or at a special meeting of shareholders called for
that purpose.  If the vacant Directorship is filled by the
shareholders and was held by a Director elected by a voting group of
shareholders, then only the holders of shares of that voting group are
entitled to vote to fill such vacancy.  A vacancy that will occur at a
specific later date by reason of a resignation effective at such later
date or otherwise may be filled before the vacancy occurs, but the new
Director may not take office until the vacancy occurs.
     
     3.15  Minutes
     
     The Board shall keep minutes of its meetings and shall cause them
to be recorded in books kept for that purpose.
     
     3.16  Executive and Other Committees
           
           3.16.1  Creation of Committees
     
     The Board, by resolution adopted by a majority of the number of
Directors fixed in the manner provided by these Bylaws, may appoint
standing or temporary committees, including an Executive Committee,
from its own number and consisting of no less than two (2) Directors.
The Board may invest such committee(s) with such powers as it may see
fit, subject to such conditions as may be prescribed by the Board,
these Bylaws, the Articles of Incorporation and the Oregon Business
Corporation Act.
           
           3.16.2  Authority of Committees
     
     Each committee shall have and may exercise all of the authority
of the Board to the extent provided in the resolution of the Board
designating the committee and any subsequent resolutions pertaining
thereto and adopted in like manner, except that no such committee
shall have the authority to:  (a) authorize distributions, except as
may be permitted by Section 3.16.2(g) of these Bylaws; (b) approve or
propose to shareholders actions required by the Oregon Business
Corporation Act to be approved by shareholders; (c) fill vacancies on
the Board or any committee thereof; (d) adopt, amend or repeal these
                                11
<PAGE> 60

Bylaws; (e) amend the Articles of Incorporation pursuant to the Oregon
Business Corporation Act; (f) approve a plan of merger not requiring
shareholder approval; (g) authorize or approve reacquisition of
shares, except within limits prescribed by the Board; or (h) authorize
or approve the issuance or sale or contract for sale of shares, or
determine the designation of relative rights, preferences and
limitations of a class or series of shares, except that Board may
authorize a committee or an officer of the Corporation to do so within
limits prescribed by the Board.
           
           3.16.3  Quorum and Manner of Acting
     
     A majority of the number of Directors composing any committee of
the Board, as established and fixed by resolution of the Board, shall
constitute a quorum for the transaction of business at any meeting of
such committee.
           
           3.16.4  Minutes of Meetings
     
     All committees so appointed shall keep regular minutes of their
meetings and shall cause them to be recorded in books kept for that
purpose.
           
           3.16.5  Resignation
     
     Any member of any committee may resign at any time by delivering
written notice thereof to the Board, the Chair of the Board or the
Corporation.  Any such resignation shall take effect at the time
specified in the notice, or if no time is specified, upon delivery.
Unless otherwise specified therein, the acceptance of such resignation
shall not be necessary to make it effective.  Once delivered, a notice
of resignation is irrevocable unless revocation is permitted by the
Board.
           
           3.16.6  Removal
     
     The Board may remove from office any member of any committee
elected or appointed by it, but only by the affirmative vote of not
less than a majority of the number of Directors fixed by or in the
manner provided by these Bylaws.
     
     3.17  Compensation
     
     By Board resolution, Directors and committee members may be paid
their expenses, if any, of attendance at each Board or committee
meeting, or a fixed sum for attendance at each Board or committee
meeting, or a stated salary as Director or a committee member, or a
combination of the foregoing.  No such payment shall preclude any
Director or committee member from serving the Corporation in any other
capacity and receiving compensation therefor.
                                 12
<PAGE> 61
SECTION 4.  OFFICERS
     
     4.1   Number
     
     The Officers of the Corporation shall be a President and a
Secretary, each of whom shall be appointed by the Board.  One or more
Vice Presidents, a Treasurer and such other Officers and assistant
Officers, including a Chair of the Board, may be appointed by the
Board; such Officers and assistant Officers to hold office for such
period, have such authority and perform such duties as are provided in
these Bylaws or as may be provided by resolution of the Board.  Any
Officer may be assigned by the Board any additional title that the
Board deems appropriate.  The Board may delegate to any Officer or
agent the power to appoint any such subordinate Officers or agents and
to prescribe their respective terms of office, authority and duties.
Any two or more offices may be held by the same person.
     
     4.2   Appointment and Term of Office
     
     The Officers of the Corporation shall be appointed annually by
the Board at the Board meeting held after the annual meeting of the
shareholders.  If the appointment of Officers is not made at such
meeting, such appointment shall be made as soon thereafter as a Board
meeting conveniently may be held.  Unless an Officer dies, resigns, or
is removed from office, he or she shall hold office until the next
annual meeting of the Board or until his or her successor is
appointed.
     
     4.3   Resignation
     
     Any Officer may resign at any time by delivering written notice
to the Corporation.  Any such resignation shall take effect at the
time specified in the notice, or if no time is specified, upon
delivery.  Unless otherwise specified therein, the acceptance of such
resignation shall not be necessary to make it effective.  Once
delivered, a notice of resignation is irrevocable unless revocation is
permitted by the Board.
     
     4.4   Removal
     
     Any Officer or agent appointed by the Board may be removed by the
Board, with or without cause, but such removal shall be without
prejudice to the contract rights, if any, of the person so removed.
Appointment of an Officer or agent shall not of itself create contract
rights.
                                   13
<PAGE> 62
     4.5   Vacancies
     
     A vacancy in any office because of death, resignation, removal,
disqualification, creation of a new office or any other cause may be
filled by the Board for the unexpired portion of the term, or for a
new term established by the Board.  If a resignation is made effective
at a later date, and the Corporation accepts such future effective
date, the Board may fill the pending vacancy before the effective
date, if the Board provides that the successor does not take office
until the effective date.
     
     4.6   Chair of the Board
     
     If appointed, the Chair of the Board shall perform such duties as
shall be assigned to him or her by the Board from time to time and
shall preside over meetings of the Board and shareholders unless
another Officer is appointed or designated by the Board as Chair of
such meeting.
     
     4.7   President
     
     The President shall be the chief executive Officer of the
Corporation unless some other Officer is so designated by the Board,
shall preside over meetings of the Board and shareholders in the
absence of a Chair of the Board and, subject to the Board's control,
shall supervise and control all of the assets, business and affairs of
the Corporation.  The President shall have authority to sign deeds,
mortgages, bonds, contracts, or other instruments, except when the
signing and execution thereof have been expressly delegated by the
Board or by these Bylaws to some other Officer or agent of the
Corporation, or are required by law to be otherwise signed or executed
by some other Officer or in some other manner.  In general, the
President shall perform all duties incident to the office of President
and such other duties as are prescribed by the Board from time to
time.
     
     4.8   Vice President
     
     In the event of the death of the President or his or her
inability to act, the Vice President (or if there is more than one
Vice President, the Vice President who was designated by the Board as
the successor to the President, or if no Vice President is so
designated, the Vice President first appointed to such office) shall
perform the duties of the President, except as may be limited by
resolution of the Board, with all the powers of and subject to all the
restrictions upon the President.  Vice Presidents shall have, to the
extent authorized by the President or the Board, the same powers as
the President to sign deeds, mortgages, bonds, contracts or other
instruments.  Vice Presidents shall perform such other duties as from
time to time may be assigned to them by the President or by the Board.
                                 14
<PAGE> 63
     4.9   Secretary
     
     The Secretary shall:  (a) prepare and keep the minutes of
meetings of the shareholders and the Board in one or more books
provided for that purpose; (b) see that all notices are duly given in
accordance with the provisions of these Bylaws or as required by law;
(c) be responsible for custody of the corporate records and seal of
the corporation; (d) keep registers of the post office address of each
shareholder and Director; (e) have general charge of the stock
transfer books of the Corporation; (f) sign, with the President or
other Officer authorized by the President or the Board, deeds,
mortgages, bonds, contracts or other instruments; and (g) in general
perform all duties incident to the office of Secretary and such other
duties as from time to time may be assigned to him or her by the
President or by the Board.  In the absence of the Secretary, an
Assistant Secretary may perform the duties of the Secretary.
     
     4.10  Treasurer
     
     If required by the Board, the Treasurer shall give a bond for the
faithful discharge of his or her duties in such amount and with such
surety or sureties as the Board shall determine.  The Treasurer shall
have charge and custody of and be responsible for all funds and
securities of the Corporation; receive and give receipts for moneys
due and payable to the Corporation from any source whatsoever, and
deposit all such moneys in the name of the Corporation in banks, trust
companies or other depositories selected in accordance with the
provisions of these Bylaws; and in general perform all of the duties
incident to the office of Treasurer and such other duties as from time
to time may be assigned to him or her by the President or by the
Board.  In the absence of the Treasurer, an Assistant Treasurer may
perform the duties of the Treasurer.
     
     4.11  Salaries
     
     The salaries of the Officers shall be fixed from time to time by
the Board or by any person or persons to whom the Board has delegated
such authority.  No Officer shall be prevented from receiving such
salary by reason of the fact that he or she is also a Director of the
Corporation.

SECTION 5.  CONTRACTS, LOANS, CHECKS AND DEPOSITS
     
     5.1   Contracts
     
     The Board may authorize any Officer or Officers, or agent or
agents, to enter into any contract or execute and deliver any
instrument in the name of and on behalf of the Corporation.  Such
authority may be general or confined to specific instances.
                              15
<PAGE> 64
     5.2   Loans to the Corporation
     
     No loans shall be contracted on behalf of the Corporation and no
evidences of indebtedness shall be issued in its name unless
authorized by a resolution of the Board.  Such authority may be
general or confined to specific instances.
     
     5.3   Loans to Directors
     
     The Corporation shall not lend money to or guarantee the
obligation of a Director unless:  (a) the particular loan or guarantee
is approved by a majority of the votes represented by the outstanding
voting shares of all classes, voting as a single voting group,
excluding the votes of the shares owned by or voted under the control
of the benefited Director; or (b) the Board determines that the loan
or guarantee benefits the Corporation and either approves the specific
loan or guarantee or a general plan authorizing the loans and
guarantees.  The fact that a loan or guarantee is made in violation of
this provision shall not affect the borrower's liability on the loan.
     
     5.4   Checks, Drafts, Etc.
     
     All checks, drafts or other orders for the payment of money,
notes or other evidences of indebtedness issued in the name of the
Corporation shall be signed by such Officer or Officers, or agent or
agents, of the Corporation and in such manner as is from time to time
determined by resolution of the Board.
     
     5.5   Deposits
     
     All funds of the Corporation not otherwise employed shall be
deposited from time to time to the credit of the Corporation in such
banks, trust companies or other depositories as the Board may select.

SECTION 6.  CERTIFICATES FOR SHARES AND THEIR TRANSFER
     
     6.1   Issuance of Shares
     
     No shares of the Corporation shall be issued unless authorized by
the Board, which authorization shall include the maximum number of
shares to be issued and the consideration to be received for each
share.  Before the Corporation issues shares, the Board shall
determine that the consideration received or to be received for such
shares is adequate.  Such determination by the Board shall be
conclusive insofar as the adequacy of consideration for the issuance
of shares relates to whether the shares are validly issued, fully paid
and nonassessable.
                                 16
<PAGE> 65
     6.2   Escrow for Shares
     
     The Board may authorize the placement in escrow of shares issued
for a contract for future services or benefits or a promissory note,
or may authorize other arrangements to restrict the transfer of
shares, and may authorize the crediting of distributions in respect of
such shares against their purchase price, until the services are
performed, the note is paid or the benefits received.  If the services
are not performed, the note is not paid, or the benefits are not
received, the Board may cancel, in whole or in part, such shares
placed in escrow or restricted and such distributions credited.
     
     6.3   Certificates for Shares
     
     Certificates representing shares of the Corporation shall be in
such form as shall be determined by the Board.  Such certificates
shall be signed by any two of the following officers:  the Chair of
the Board, the President, any Vice President, the Treasurer, the
Secretary or any Assistant Secretary.  Any or all of the signatures on
a certificate may be facsimiles if the certificate is manually signed
on behalf of a transfer agent or a registrar other than the
Corporation itself or an employee of the Corporation.  All
certificates shall be consecutively numbered or otherwise identified.
     
     6.4   Stock Records
     
     The stock transfer books shall be kept at the registered office
or principal place of business of the Corporation or at the office of
the Corporation's transfer agent or registrar.  The name and address
of each person to whom certificates for shares are issued, together
with the class and number of shares represented by each such
certificate and the date of issue thereof, shall be entered on the
stock transfer books of the Corporation.  The person in whose name
shares stand on the books of the Corporation shall be deemed by the
Corporation to be the owner thereof for all purposes.
     
     6.5   Restriction on Transfer
           
           6.5.1   Securities Laws
     
     Except to the extent that the Corporation has obtained an opinion
of counsel acceptable to the Corporation that transfer restrictions
are not required under applicable securities laws, or has otherwise
satisfied itself that such transfer restrictions are not required, all
certificates representing shares of the Corporation shall bear
conspicuously on the front or back of the certificate a legend or
legends describing the restriction or restrictions.
                                17
<PAGE> 66  
           6.5.2   Other Restrictions
     
     In addition, the front or back of all certificates shall include
conspicuous written notice of any further restrictions which may be
imposed on the transferability of such shares.
     
     6.6   Transfer of Shares
     
     Transfer of shares of the Corporation shall be made only on the
stock transfer books of the Corporation pursuant to authorization or
document of transfer made by the holder of record thereof or by his or
her legal representative, who shall furnish proper evidence of
authority to transfer, or by his or her attorney-in-fact authorized by
power of attorney duly executed and filed with the Secretary of the
Corporation.  All certificates surrendered to the Corporation for
transfer shall be cancelled and no new certificate shall be issued
until the former certificates for a like number of shares shall have
been surrendered and cancelled.
     
     6.7   Lost or Destroyed Certificates
     
     In the case of a lost, destroyed or mutilated certificate, a new
certificate may be issued therefor upon such terms and indemnity to
the Corporation as the Board may prescribe.
     
     6.8   Transfer Agent and Registrar
     
     The Board may from time to time appoint one or more Transfer
Agents and one or more Registrars for the shares of the Corporation,
with such powers and duties as the Board shall determine by
resolution.
     
     6.9   Officer Ceasing to Act
     
     In case any officer who has signed or whose facsimile signature
has been placed upon a stock certificate shall have ceased to be such
officer before such certificate is issued, it may be issued by the
Corporation with the same effect as if the signer were such officer at
the date of its issuance.
     
     6.10  Fractional Shares
     
     The Corporation shall not issue certificates for fractional
shares.
                                 18
<PAGE> 67
SECTION 7.  BOOKS AND RECORDS
     
     The Corporation shall keep correct and complete books and records
of account, stock transfer books, minutes of the proceedings of its
shareholders and Board and such other records as may be necessary or
advisable.

SECTION 8.  FISCAL YEAR
     
     The fiscal year of the Corporation shall be the twelve month
period ending on March 31 of each year, provided that if a different
fiscal year is at any time selected for purposes of federal income
taxes, the fiscal year shall be the year so selected.

SECTION 9.  SEAL
     
     The seal of the Corporation shall consist of the name of the
Corporation, the year of its incorporation and the state of its
incorporation.

SECTION 10.  INDEMNIFICATION
     
     10.1  Directors and Officers
     
     The Corporation shall indemnify its directors and officers to the
fullest extent not prohibited by law.
     
     10.2  Officers, Employees and Other Agents
     
     The Corporation shall have the power to indemnify its officers,
employees and other agents to the fullest extent not prohibited by
law.
     
     10.3  No Presumption of Bad Faith
     
     The termination of any proceeding by judgment, order, settlement,
conviction or upon a plea of nolo contendere or its equivalent shall
not, of itself, create a presumption that the person did not act in
good faith and in a manner which the person reasonably believed to be
in or not opposed to the best interests of this Corporation, or, with
respect to any criminal proceeding, that the person had reasonable
cause to believe that the conduct was unlawful.
     
     10.4  Advances of Expenses
     
     The expenses incurred by a director or officer in any proceeding
shall be paid by the Corporation in advance at the written request of
the director or officer, if the director or officer:
                                   19
<PAGE> 68 
     10.4.1  Furnishes the Corporation a written affirmation of such
person's good faith belief that such person is entitled to be
indemnified by the Corporation; and
     
     10.4.2  Furnishes the Corporation a written undertaking to repay
such advance to the extent that it is ultimately determined by a court
that such person is not entitled to be indemnified by the Corporation.
Such advances shall be made without regard to the person's ability to
repay such expenses and without regard to the person's ultimate
entitlement to indemnification under this Bylaw or otherwise.
     
     10.5  Enforcement
     
     Without the necessity of entering into an express contract, all
rights to indemnification and advances under this Bylaw shall be
deemed to be contractual rights and be effective to the same extent
and as if provided for in a contract between the Corporation and the
director or officer who serves in such capacity at any time while this
Bylaw and any other applicable law, if any, are in effect.  Any right
to indemnification or advances granted by this Bylaw to a director or
officer shall be enforceable by or on behalf of the person holding
such right in any court of competent jurisdiction if (a) the claim for
indemnification or advances is denied, in whole or in part, or (b) no
disposition of such claim is made within ninety (90) days of request
thereof.  The claimant in such enforcement action, if successful in
whole or in part, shall be entitled to be also paid the expense of
prosecuting the claim.  It shall be a defense to any such action
(other than an action brought to enforce a claim for expenses incurred
in connection with any proceeding in advance of its final disposition
when the required affirmation and undertaking have been tendered to
the Corporation) that the claimant has not met the standards of
conduct which makes it permissible under the law for the Corporation
to indemnify the claimant, but the burden of proving such defense
shall be on the Corporation.  Neither the failure of the Corporation
(including its Board of Directors, independent legal counsel or its
shareholders) to have made a determination prior to the commencement
of such action that indemnification of the claimant is proper in the
circumstances because the claimant has met the applicable standard of
conduct, nor an actual determination by the Corporation (including its
Board of Directors, independent legal counsel or its shareholders)
that the claimant has not met such applicable standard of conduct,
shall be a defense to the action or create a presumption that the
claimant has not met the applicable standard of conduct.
     
     10.6  Nonexclusivity of Rights
     
     The rights conferred on any person by this Bylaw shall not be
exclusive of any other right which such person may have or hereafter
acquire under any statute, provision of articles of incorporation,
bylaws, agreement, vote of shareholders or disinterested directors or
                                  20
<PAGE> 69
otherwise, both as to action in the person's official capacity and as
to action in another capacity while holding office.  The Corporation
is specifically authorized to enter into individual contracts with any
or all of its directors, officers, employees or agents respecting
indemnification and advances to the fullest extent not prohibited by
law.
     
     10.7  Survival of Rights
     
     The rights conferred on any person by this Bylaw shall continue
as to a person who has ceased to be a director, officer, employee or
other agent and shall inure to the benefit of the heirs, executors and
administrators of such a person.
     
     10.8  Insurance
     
     To the fullest extent not prohibited by law, the Corporation,
upon approval by the Board of Directors, may purchase insurance on
behalf of any person required or permitted to be indemnified pursuant
to this Bylaw.
     
     10.9  Amendments to Law
     
     For purposes of this Bylaw, the meaning of "law" within the
phrase "to the fullest extent not prohibited by law" shall include,
but not be limited to, the Oregon Business Corporation Act, as the
same exists on the date hereof or as it may be amended; provided,
however, that in the case of any such amendment, such amendment shall
apply only to the extent that it permits the Corporation to provide
broader indemnification rights than the Act permitted the Corporation
to provide prior to such amendment.
     
     10.10 Savings Clause
     
     If this Bylaw or any portion hereof shall be invalidated on any
ground by any court of competent jurisdiction, the Corporation shall
indemnify each director, officer or other agent to the fullest extent
permitted by any applicable portion of this Bylaw that shall not have
been invalidated, or by any other applicable law.
     
     10.11 Certain Definitions
     
     For the purposes of this Section, the following definitions shall
apply:
     
          10.11.1  The term "proceeding" shall be broadly construed
and shall include, without limitation, the investigation, preparation,
prosecution, defense, settlement and appeal of any threatened, pending
or completed action, suit or proceeding, whether brought in the right
of the Corporation or otherwise and whether civil, criminal,
administrative or investigative, in which the director or officer may
                                  21
<PAGE> 70
be or may have been involved as a party or otherwise by reason of the
fact that the director or officer is or was a director or officer of
the Corporation or is or was serving at the request of the Corporation
as a director, officer, employee or agent of another corporation,
partnership, joint venture, trust or other enterprise.
     
          10.11.2  The term "expenses" shall be broadly construed and
shall include, without limitation, all costs, charges and expenses
(including fees and disbursements of attorneys, accountants and other
experts) actually and reasonably incurred by a director or officer in
connection with any proceeding, all expenses of investigations,
judicial or administrative proceedings or appeals, and any expenses of
establishing a right to indemnification under these Bylaws, but shall
not include amounts paid in settlement, judgments or fines.
     
          10.11.3  "Corporation" shall mean Synthetech, Inc., and any
successor corporation thereof.
     
          10.11.4  Reference to a "director," "officer," "employee" or
"agent" of the Corporation shall include, without limitation,
situations where such person is serving at the request of the
Corporation as a director, officer, employee, trustee or agent of
another corporation, partnership, joint venture, trust or other
enterprise.
     
          10.11.5  References to "other enterprises" shall include
employee benefit plans.  References to "fines" shall include any
excise taxes assessed on a person with respect to any employee benefit
plan.  References to "serving at the request of the Corporation" shall
include any service as a director, officer, employee or agent of the
Corporation which imposes duties on, or involves services by, such
director, officer, employee or agent with respect to an employee
benefit plan, its participants, or beneficiaries.  A person who acted
in good faith and in a manner the person reasonably believed to be in
the interest of the participants and beneficiaries of an employee
benefit plan shall be deemed to have acted in a manner "not opposed to
the best interests of the Corporation" as referred to in this Bylaw.

SECTION 11.  AMENDMENTS
     
     These Bylaws may be altered, amended or repealed and new Bylaws
may be adopted by the Board at any regular or special meeting of the
Board; provided, however, that the shareholders, in amending or
repealing a particular Bylaw, may provide expressly that the Board may
not amend or repeal that Bylaw.  The shareholders may also make,
alter, amend and repeal the Bylaws of the Corporation at any annual
meeting or at a special meeting called for that purpose.  All Bylaws
made by the Board may be amended, repealed, altered or modified by the
shareholders at any regular or special meeting called for that
purpose.
                                   22
<PAGE> 71
SECTION 12.  CONTROL SHARE ACQUISITION STATUTE
     
     The provisions of ORS 60.801-60.816 shall apply fully to the
acquisition of shares of the Corporation.
     
     The foregoing Bylaws were adopted by the Incorporator of the
Corporation on November 8, 1990.
                                 23


<PAGE> 72
                                                         Exhibit 10.10
                                                         of Form 10KSB
                                                                      
                                   
                           SYNTHETECH, INC.
                                   
                   1995 INCENTIVE COMPENSATION PLAN
                                   
              As Amended and Restated on November 7, 1996
                                   
                                   
                                   
                                   
                                   

SECTION 1.  PURPOSE
     
     The purpose of the Synthetech, Inc. 1995 Incentive Compensation
Plan (the "Plan") is to enhance the long-term profitability and
stockholder value of Synthetech, Inc., an Oregon corporation (the
"Company"), by offering incentives and rewards to those
employees, directors, consultants and agents of the Company and its
Subsidiaries, if any (as defined in Section 2 below), who are key to
the Company's growth and success, and to encourage them to remain in
the service of the Company and its Subsidiaries and to acquire and
maintain stock ownership in the Company.

SECTION 2.  DEFINITIONS
     
     For purposes of the Plan, the following terms shall be defined as
set forth below:
     
     2.1    Award
     
     "Award" means an award or grant made to a Participant pursuant to
the Plan, including, without limitation, awards or grants of Options,
Stock Awards, or any combination of the foregoing.
     
     2.2    Board
     
     "Board" means the Board of Directors of the Company.
     
     2.3    Cause
     
     "Cause" means dishonesty, fraud, misconduct, unauthorized use or
disclosure of confidential information or trade secrets, or conviction
or confession of a crime punishable by law (except minor violations),
                                  1
<PAGE> 73
in each case as determined by the Plan Administrator, and its
determination shall be conclusive and binding.
     
     2.4    Code
     
     "Code" means the Internal Revenue Code of 1986, as amended from
time to time.
     
     2.5    Common Stock
     
     "Common Stock" means the common stock, par value $.001 per share,
of the Company.
     
     2.6    Corporate Transaction
     
     "Corporate Transaction" means any of the following events:
          
          (a)  Approval by the holders of the Common Stock of any
merger or consolidation of the Company in which the Company is not the
continuing or surviving corporation or pursuant to which shares of the
Common Stock are converted into cash, securities or other property,
other than a merger of the Company in which the holders of the Common
Stock immediately prior to the merger have substantially the same
proportionate ownership of common stock of the surviving corporation
immediately after the merger;
          
          (b)  Approval by the holders of the Common Stock of any
sale, lease, exchange or other transfer in one transaction or a series
of related transactions of all or substantially all of the Company's
assets other than a transfer of the Company's assets to a majority-
owned subsidiary (as the term "subsidiary" is defined in Section 8.3
of the Plan) of the Company; or
          
          (c)  Approval by the holders of the Common Stock of any plan
or proposal for the liquidation or dissolution of the Company.
     
     2.7    Disability
     
     "Disability" means "disability" as that term is defined for
purposes of the Company's Long Term Disability Plan or other similar
successor plan applicable to salaried employees.
     
     2.8    Early Retirement
     
     "Early Retirement" means retirement as that term is defined by
the Plan Administrator from time to time for purposes of the Plan.
                                  2
<PAGE> 74
     2.9    Exchange Act
     
     "Exchange Act" means the Securities Exchange Act of 1934, as
amended.
     
     2.10   Fair Market Value
     
     "Fair Market Value" shall be as established in good faith by the
Plan Administrator or (a) if the Common Stock is listed on the Nasdaq
National Market, the closing selling price for the Common Stock as
reported by the Nasdaq National Market for a single trading day or
(b) if the Common Stock is listed on the New York Stock Exchange or
the American Stock Exchange, the closing selling price for the Common
Stock as such price is officially quoted in the composite tape of
transactions on such exchange for a single trading day.  If there is
no such reported price for the Common Stock for the date in question,
then such price on the last preceding date for which such price exists
shall be determinative of Fair Market Value.
     
     2.11   Good Reason
     
     "Good Reason" means the occurrence of any of the following events
or conditions:
          
          (a)  a change in the Holder's status, title, position or
responsibilities (including reporting responsibilities) that, in the
Holder's reasonable judgment, represents a substantial reduction of
the status, title, position or responsibilities as in effect
immediately prior thereto; the assignment to the Holder of any duties
or responsibilities that, in the Holder's reasonable judgment, are
inconsistent with such status, title, position or responsibilities; or
any removal of the Holder from or failure to reappoint or reelect the
Holder to any of such positions, except in connection with the
termination of the Holder's employment for Cause, for Disability or as
a result of his or her death, or by the Holder other than for Good
Reason;
          
          (b)  a reduction in the Holder's annual base salary;
          
          (c)  the Company's requiring the Holder (without the
Holder's consent) to be based at any place outside a 35-mile radius of
his or her place of employment prior to a Corporate Transaction,
except for reasonably required travel on the Company's business that
is not materially greater than such travel requirements prior to the
Corporate Transaction;
          
          (d)  the Company's failure to (i) continue in effect any
material compensation or benefit plan (or the substantial equivalent
thereof) in which the Holder was participating at the time of a
Corporate Transaction, including, but not limited to, the Plan, or
(ii) provide the Holder with compensation and benefits at least equal
                                3
<PAGE> 75
(in terms of benefit levels and/or reward opportunities) to those
provided for under each employee benefit plan, program and practice as
in effect immediately prior to the Corporate Transaction (or as in
effect following the Corporate Transaction, if greater);
          
          (e)  any material breach by the Company of any provision of
the Plan; or
          
          (f)  any purported termination of the Holder's employment or
service for Cause by the Company that does not comply with the terms
of the Plan.
     
     2.12   Grant Date
     
     "Grant Date" means the date designated in a resolution of the
Plan Administrator as the date an Award is granted.  If the Plan
Administrator does not designate a Grant Date in the resolution, the
Grant Date shall be the date the Plan Administrator adopted the
resolution.
     
     2.13   Holder
     
     "Holder" means the Participant to whom an Award is granted, or
the personal representative of a Holder who has died.
     
     2.14   Incentive Stock Option
     
     "Incentive Stock Option" means an option to purchase Common Stock
granted under Section 7 of the Plan with the intention that it qualify
as an "incentive stock option" as that term is defined in Section 422
of the Code.
     
     2.15   Nonqualified Stock Option
     
     "Nonqualified Stock Option" means an option to purchase Common
Stock granted under Section 7 of the Plan other than an Incentive
Stock Option.
     
     2.16   Option
     
     "Option" means the right to purchase Common Stock granted under
Section 7 of the Plan.
     
     2.17   Participant
     
     "Participant" means an individual who is a Holder of an Award or,
as the context may require, any employee, director, consultant or
agent of the Company or a Subsidiary who has been designated by the
                                4
<PAGE> 76
Plan Administrator as eligible to participate in the Plan.
     
     2.18   Plan Administrator
     
     "Plan Administrator" means the Board and/or any committee of the
Board designated to administer the Plan under Section 3.1 of the Plan.
     
     2.19   Restricted Stock
     
     "Restricted Stock" means shares of Common Stock granted under
Section 9 of the Plan the rights of ownership of which are subject to
restrictions prescribed by the Plan Administrator.
     
     2.20   Retirement
     
     "Retirement" means retirement as that term is defined by the Plan
Administrator from time to time for purposes of the Plan.
     
     2.21   Stock Award
     
     "Stock Award" means an Award granted under Section 9 of the Plan.
     
     2.22   Subsidiary
     
     "Subsidiary," except as expressly provided otherwise, means any
entity that is directly or indirectly controlled by the Company or in
which the Company has a significant ownership interest, as determined
by the Plan Administrator, and any entity that may become a direct or
indirect parent of the Company.

SECTION 3.  ADMINISTRATION
     
     3.1    Plan Administrator
     
     The Plan shall be administered by the Board and/or a committee or
committees (which term includes subcommittees) appointed by, and
consisting of two or more members of, the Board.  The Board may
delegate the responsibility for administering the Plan with respect to
designated classes of eligible Participants to different committees,
subject to such limitations as the Board deems appropriate.  Committee
members shall serve for such term as the Board may determine, subject
to removal by the Board at any time.  The composition of any committee
responsible for administering the Plan with respect to officers and
directors of the Company who are subject to Section 16 of the Exchange
Act with respect to securities of the Company shall comply with the
                                 5
<PAGE> 77
requirements of Rule 16b-3 under Section 16(b) of the Exchange Act.
     
     3.2    Administration and Interpretation by the Plan
            Administrator
     
     Except for the terms and conditions explicitly set forth in the
Plan, the Plan Administrator shall have exclusive authority, in its
discretion, to determine all matters relating to Awards under the
Plan, including the selection of individuals to be granted Awards, the
type of Awards, the number of shares of Common Stock subject to an
Award, all terms, conditions, restrictions and limitations, if any, of
an Award and the terms of any instrument that evidences the Award.
The Plan Administrator shall also have exclusive authority to
interpret the Plan and may from time to time adopt, and change, rules
and regulations of general application for the Plan's administration.
The Plan Administrator's interpretation of the Plan and its rules and
regulations, and all actions taken and determinations made by the Plan
Administrator pursuant to the Plan, shall be conclusive and binding on
all parties involved or affected.  The Plan Administrator may delegate
administrative duties to such of the Company's officers as it so
determines.

SECTION 4.  STOCK SUBJECT TO THE PLAN
     
     4.1    Authorized Number of Shares
     
     Subject to adjustment from time to time as provided in
Section 12.1 of the Plan, a maximum of Seven Hundred Fifty Thousand
(750,000) shares of Common Stock shall be available for issuance under
the Plan, except that any shares of Common Stock that, as of the date
the Plan is approved by the Company's stockholders, are available for
issuance under the Company's Amended and Restated 1990 Stock Option
Plan, as amended (or that thereafter become available for issuance
under that plan in accordance with its terms as in effect on such
date) and that are not issued under that plan shall be added to the
aggregate number of shares available for issuance under the Plan.
Shares issued under the Plan shall be drawn from authorized and
unissued shares or shares now held or subsequently acquired by the
Company as treasury shares.
     
     4.2    Limitations
     
     Subject to adjustment from time to time as provided in
Section 12.1 of the Plan, not more than 350,000 shares of Common Stock
may be made subject to Awards under the Plan to any individual
Participant in the aggregate over the term of the Plan, such
limitation to be applied in a manner consistent with the requirements
of, and only to the extent required for compliance with, the exclusion
from the limitation on deductibility of compensation under Section
162(m) of the Code.
                                 6
<PAGE> 78     
     4.3    Reuse of Shares
     
     Any shares of Common Stock that have been made subject to an
Award that cease to be subject to the Award (other than by reason of
exercise or payment of the Award to the extent it is exercised for or
settled in shares), including, without limitation, in connection with
the cancellation of an Award and the grant of a replacement Award,
shall again be available for issuance in connection with future grants
of Awards under the Plan.  Shares that are subject to tandem Awards
shall be counted only once.

SECTION 5.  ELIGIBILITY
     
     Awards may be granted under the Plan to those officers, key
employees and directors of the Company and its Subsidiaries as the
Plan Administrator from time to time selects.  Awards may also be made
to consultants and agents who provide services to the Company and its
Subsidiaries, if any.

SECTION 6.  AWARDS
     
     6.1    Form and Grant of Awards
     
     The Plan Administrator shall have the authority, in its sole
discretion, to determine the type or types of Awards to be made under
the Plan.  Such Awards may include Incentive Stock Options,
Nonqualified Stock Options and Stock Awards.  Awards may be granted
singly, in combination or in tandem so that the settlement or payment
of one automatically reduces or cancels the other.  Awards may also be
made in combination or in tandem with, in replacement of, as
alternatives to, or as the payment form for, grants or rights under
any other employee or compensation plan of the Company.
     
     6.2    Acquired Company Awards
     
     Notwithstanding anything in the Plan to the contrary, the Plan
Administrator may grant Awards under the Plan in substitution for
awards issued under other plans, or assume under the Plan awards
issued under other plans, if the other plans are or were plans of
other entities ("Acquired Entities") (or the parent of the Acquired
Entity) and the new Award is substituted, or the old award is assumed,
by reason of a merger, consolidation, acquisition of property or of
stock, reorganization or liquidation (the "Acquisition Transaction").
In the event that a written agreement pursuant to which the
Acquisition Transaction is completed is approved by the Board and said
agreement sets forth the terms and conditions of the substitution for
or assumption of outstanding awards of the Acquired Entity, said terms
and conditions shall be deemed to be the action of the Plan
Administrator without any further action by the Plan Administrator,
                                 7
<PAGE> 79
except as may be required for compliance with Rule 16b-3 under the
Exchange Act, and the persons holding such Awards shall be deemed to
be Participants and Holders.

SECTION 7.  AWARDS OF OPTIONS
     
     7.1    Grant of Options
     
     The Plan Administrator is authorized under the Plan, in its sole
discretion, to issue Options as Incentive Stock Options or as
Nonqualified Stock Options, which shall be appropriately designated.
     
     7.2    Option Exercise Price
     
     The exercise price for shares purchased under an Option shall be
as determined by the Plan Administrator, but shall not be less than
100% of the Fair Market Value of the Common Stock on the Grant Date
with respect to Incentive Stock Options and not less than 10% of the
Fair Market Value of the Common Stock on the Grant Date with respect
to Nonqualified Stock Options.
     
     7.3    Term of Options
     
     The term of each Option shall be as established by the Plan
Administrator or, if not so established, shall be ten years from the
Grant Date.
     
     7.4    Exercise of Options
     
     The Plan Administrator shall establish and set forth in each
instrument that evidences an Option the time at which or the
installments in which the Option shall become exercisable, which
provisions may be waived or modified by the Plan Administrator at any
time.
     
     To the extent that the right to purchase shares has accrued
thereunder, an Option may be exercised from time to time by written
notice to the Company, in accordance with procedures established by
the Plan Administrator, setting forth the number of shares with
respect to which the Option is being exercised and accompanied by
payment in full as described in Section 7.5 of the Plan.  In no case
may an Option be exercised as to less than 100 shares at any one time
(or the lesser number of remaining shares covered by the Option).
     
     7.5    Payment of Exercise Price
     
     The exercise price for shares purchased under an Option shall be
paid in full to the Company by delivery of consideration equal to the
product of the Option exercise price and the number of shares
                                 8
<PAGE> 80
purchased.  Such consideration must be paid in cash, except that the
Plan Administrator may, either at the time the Option is granted or at
any time before it is exercised and subject to such limitations as the
Plan Administrator may determine, authorize payment in cash and/or one
or more of the following alternative forms:  (i) Common Stock already
owned by the Holder for at least six months (or any shorter period
necessary to avoid a charge to the Company's earnings for financial
reporting purposes) having a Fair Market Value on the day prior to the
exercise date equal to the aggregate Option exercise price; (ii) a
promissory note authorized pursuant to Section 11 of the Plan;
(iii) delivery of a properly executed exercise notice, together with
irrevocable instructions, to (a) a brokerage firm designated by the
Company to deliver promptly to the Company the aggregate amount of
sale or loan proceeds to pay the Option exercise price and any
withholding tax obligations that may arise in connection with the
exercise and (b) the Company to deliver the certificates for such
purchased shares directly to such brokerage firm, all in accordance
with the regulations of the Federal Reserve Board; or (iv) such other
consideration as the Plan Administrator may permit.
     
     7.6    Post-Termination Exercises
     
     The Plan Administrator shall establish and set forth in each
instrument that evidences an Option whether the Option will continue
to be exercisable, and the terms and conditions of such exercise, if a
Holder ceases to be employed by, or to provide services to, the
Company or its Subsidiaries, which provisions may be waived or
modified by the Plan Administrator at any time.  If not so established
in the instrument evidencing the Option, the Option will be
exercisable according to the following terms and conditions, which may
be waived or modified by the Plan Administrator at any time.  In case
of termination of the Holder's employment or services other than by
reason of death or Cause, the Option shall be exercisable, to the
extent of the number of shares purchasable by the Holder at the date
of such termination, only:  (i) within three years if the termination
of the Holder's employment or services are coincident with Retirement,
Early Retirement at the Company's request or Disability or (ii) within
three months after the date the Holder ceases to be an employee,
director, consultant or agent of the Company or a Subsidiary if
termination of the Holder's employment or services is for any reason
other than Retirement, Early Retirement at the Company's request or
Disability, but in no event later than the remaining term of the
Option.  Any Option exercisable at the time of the Holder's death may
be exercised, to the extent of the number of shares purchasable by the
Holder at the date of the Holder's death, by the personal
representative of the Holder's estate entitled thereto at any time or
from time to time within three years after the date of death, but in
no event later than the remaining term of the Option.  In case of
termination of the Holder's employment or services for Cause, the
Option shall automatically terminate upon first notification to the
                                9
<PAGE> 81
Holder of such termination, unless the Plan Administrator determines
otherwise.  If a Holder's employment or services with the Company are
suspended pending an investigation of whether the Holder shall be
terminated for Cause, all the Holder's rights under any Option
likewise shall be suspended during the period of investigation.  A
transfer of employment or services between or among the Company and
its Subsidiaries shall not be considered a termination of employment
or services.  Unless the Plan Administrator determines otherwise, a
leave of absence approved in accordance with Company procedures shall
not be considered a termination of employment or services, except that
with respect to Incentive Stock Options such leave of absence shall be
subject to any requirements of Section 422 of the Code.

SECTION 8.  INCENTIVE STOCK OPTION LIMITATIONS
     
     To the extent required by Section 422 of the Code, Incentive
Stock Options shall be subject to the following additional terms and
conditions:
     
     8.1    Dollar Limitation
     
     To the extent the aggregate Fair Market Value (determined as of
the Grant Date) of Common Stock with respect to which Incentive Stock
Options are exercisable for the first time during any calendar year
(under the Plan and all other stock option plans of the Company)
exceeds $100,000, such portion in excess of $100,000 shall be treated
as a Nonqualified Stock Option.  In the event the Participant holds
two or more such Options that become exercisable for the first time in
the same calendar year, such limitation shall be applied on the basis
of the order in which such Options are granted.
     
     8.2    10% Stockholders
     
     If a Participant owns 10% or more of the total voting power of
all classes of the Company's stock, then the exercise price per share
of an Incentive Stock Option shall not be less than 110% of the Fair
Market Value of the Common Stock on the Grant Date and the Option term
shall not exceed five years.
     
     8.3    Eligible Employees
     
     Individuals who are not employees of the Company or one of its
parent corporations or subsidiary corporations may not be granted
Incentive Stock Options.  For purposes of this Section 8.3 of the
Plan, "parent corporation" and "subsidiary corporation" shall have the
meanings attributed to those terms for purposes of Section 422 of the
Code.
                                  10
<PAGE> 82
     8.4    Term
     
     The term of an Incentive Stock Option shall not exceed 10 years.
     
     8.5    Exercisability
     
     An Option designated as an Incentive Stock Option must be
exercised within three months after termination of employment for
reasons other than death to qualify for Incentive Stock Option tax
treatment, except that in the case of termination of employment due to
Disability, such Option must be exercised within one year after such
termination.

SECTION 9.  STOCK AWARDS
     
     9.1    Grant of Stock Awards
     
     The Plan Administrator is authorized to make Awards of Common
Stock to Participants on such terms and conditions and subject to such
restrictions, if any (whether based on performance standards, periods
of service or otherwise), as the Plan Administrator shall determine,
which terms, conditions and restrictions shall be set forth in the
instrument evidencing the Award.  The terms, conditions and
restrictions that the Plan Administrator shall have the power to
determine shall include, without limitation, the manner in which
shares subject to Stock Awards are held during the periods they are
subject to restrictions and the circumstances under which forfeiture
of Restricted Stock shall occur by reason of termination of the
Holder's services.
     
     9.2    Issuance of Shares
     
     Upon the satisfaction of any terms, conditions and restrictions
prescribed in respect to a Stock Award, or upon the Holder's release
from any terms, conditions and restrictions of a Stock Award, as
determined by the Plan Administrator, the Company shall deliver, as
soon as practicable, to the Holder or, in the case of the Holder's
death, to the personal representative of the Holder's estate or as the
appropriate court directs, a stock certificate for the appropriate
number of shares of Common Stock.
     
     9.3    Waiver of Restrictions
     
     Notwithstanding any other provisions of the Plan, the Plan
Administrator may, in its sole discretion, waive the forfeiture period
and any other terms, conditions or restrictions on any Restricted
Stock under such circumstances and subject to such terms and
conditions as the Plan Administrator shall deem appropriate.
                              11
<PAGE> 83
SECTION 10. LOANS, LOAN GUARANTEES AND INSTALLMENT PAYMENTS
     
     To assist a Holder (including a Holder who is an officer or
director of the Company) in acquiring shares of Common Stock pursuant
to an Award granted under the Plan, the Plan Administrator may
authorize, either at the Grant Date or at any time before the
acquisition of Common Stock pursuant to the Award, (i) the extension
of a loan to the Holder by the Company, (ii) the payment by the Holder
of the purchase price, if any, of the Common Stock in installments, or
(iii) the guarantee by the Company of a loan obtained by the grantee
from a third party.  The terms of any loans, installment payments or
guarantees, including the interest rate and terms of repayment, will
be subject to the Plan Administrator's discretion.  Loans, installment
payments and guarantees may be granted with or without security.  The
maximum credit available is the purchase price, if any, of the Common
Stock acquired plus the maximum federal and state income and
employment tax liability that may be incurred in connection with the
acquisition.

SECTION 11. ASSIGNABILITY
     
     No Option granted under the Plan may be assigned or transferred
by the Holder other than by will or by the laws of descent and
distribution, and during the Holder's lifetime, such Awards may be
exercised only by the Holder.  Notwithstanding the foregoing, and to
the extent permitted by Rule 16b-3 under the Exchange Act and
Section 422 of the Code, the Plan Administrator, in its sole
discretion, may permit such assignment, transfer and exercisability
and may permit a Holder of such Awards to designate a beneficiary who
may exercise the Award or receive compensation under the Award after
the Holder's death.

SECTION 12. ADJUSTMENTS
     
     12.1   Adjustment of Shares
     
     In the event that at any time or from time to time a stock
dividend, stock split, spin-off, combination or exchange of shares,
recapitalization, merger, consolidation, distribution to stockholders
other than a normal cash dividend, or other change in the Company's
corporate or capital structure results in (i) the outstanding shares,
or any securities exchanged therefor or received in their place, being
exchanged for a different number or class of securities of the Company
or of any other corporation or (ii) new, different or additional
securities of the Company or of any other corporation being received
by the holders of shares of Common Stock of the Company, then the Plan
Administrator, in its sole discretion, shall make such equitable
adjustments as it shall deem appropriate in the circumstances in
(a) the maximum number of and class of securities subject to the Plan
as set forth in Section 4.1 of the Plan, (b) the maximum number and
                                 12
<PAGE> 84
class of securities that may be made subject to Awards to any
individual Participant as set forth in Section 4.2 of the Plan, and
(c) the number and class of securities that are subject to any
outstanding Award and the per share price of such securities, without
any change in the aggregate price to be paid therefor.  The
determination by the Plan Administrator as to the terms of any of the
foregoing adjustments shall be conclusive and binding.
     
     12.2   Corporate Transaction
     
     Except as otherwise provided in the instrument that evidences the
Award, in the event of any Corporate Transaction, each Option or Stock
Award that is at the time outstanding shall automatically accelerate
so that each such Award shall, immediately prior to the specified
effective date for the Corporate Transaction, become 100% vested,
except that such acceleration will not occur if in the opinion of the
Company's accountants it would render unavailable "pooling of
interest" accounting for a Corporate Transaction that would otherwise
qualify for such accounting treatment.  Such Award shall not so
accelerate, however, if and to the extent:  (i) such Award is, in
connection with the Corporate Transaction, either to be assumed by the
successor corporation or parent thereof or to be replaced with a
comparable award for the purchase of shares of the capital stock of
the successor corporation or its parent corporation, (ii) such Award
is to be replaced with a cash incentive program of the successor
corporation that preserves the spread existing at the time of the
Corporate Transaction and provides for subsequent payout in accordance
with the same vesting schedule applicable to such Award, or (iii) the
acceleration of such Award is subject to other limitations imposed by
the instrument evidencing the Award.  The determination of Award
comparability under clause (i) above shall be made by the Plan
Administrator, and its determination shall be conclusive and binding.
All such Awards shall terminate and cease to remain outstanding
immediately following the consummation of the Corporate Transaction,
except to the extent assumed by the successor corporation or its
parent corporation.  Any such Awards that are assumed or replaced in
the Corporate Transaction and do not otherwise accelerate at that time
shall be accelerated in the event the Holder's employment or services
should subsequently terminate within two years following such
Corporate Transaction, unless such employment or services are
terminated by the Company for Cause or by the Holder voluntarily
without Good Reason.  Notwithstanding the foregoing, no Incentive
Stock Option shall become exercisable pursuant to this Section 12.2
without the Holder's consent, if the result would be to cause such
Option not to be treated as an Incentive Stock Option (whether by
reason of the annual limitation described in Section 8.1 of the Plan
or otherwise).
                                 13
<PAGE> 85
     12.3   Further Adjustment of Awards
     
     Without limiting the preceding Section 12.2 of the Plan, the Plan
Administrator shall have the discretion, exercisable at any time
before a sale, merger, consolidation, reorganization, liquidation or
change in control of the Company, as defined by the Plan
Administrator, to take such further action as it determines to be
necessary or advisable, and fair and equitable to Participants, with
respect to Awards.  Such authorized action may include (but shall not
be limited to) establishing, amending or waiving the type, terms,
conditions or duration of, or restrictions on, Awards so as to provide
for earlier, later, extended or additional time for exercise, payment
or settlement or lifting restrictions, differing methods for
calculating payments or settlements, alternate forms and amounts of
payments and settlements and other modifications, and the Plan
Administrator may take such actions with respect to all Participants,
to certain categories of Participants or only to individual
Participants.  The Plan Administrator may take such actions before or
after granting Awards to which the action relates and before or after
any public announcement with respect to such sale, merger,
consolidation, reorganization, liquidation or change in control that
is the reason for such action.
     
     12.4   Limitations
     
     The grant of Awards will in no way affect the Company's right to
adjust, reclassify, reorganize or otherwise change its capital or
business structure or to merge, consolidate, dissolve, liquidate or
sell or transfer all or any part of its business or assets.

SECTION 13. WITHHOLDING OF TAXES
     
     The Company may require the Holder to pay to the Company the
amount of any withholding taxes that the Company is required to
withhold with respect to the grant, exercise, payment or settlement of
any Award.  In such instances, the Plan Administrator may, in its
discretion and subject to the Plan and applicable law, permit the
Holder to satisfy withholding obligations, in whole or in part, by
paying cash, by electing to have the Company withhold shares of Common
Stock or by transferring shares of Common Stock to the Company, in
such amounts as are equivalent to the Fair Market Value of the
withholding obligation.

SECTION 14. AMENDMENT AND TERMINATION OF PLAN
     
     14.1   Amendment of Plan
     
     The Plan may be amended by the stockholders of the Company.  The
Board may also amend the Plan in such respects as it shall deem
advisable; however, to the extent required for compliance with Rule
                              14
<PAGE> 86
16b-3 under the Exchange Act, Section 422 of the Code or any
applicable law or regulation, stockholder approval will be required
for any amendment that will (i) increase the total number of shares as
to which Options may be granted or that may be issued as Restricted
Stock, (ii) materially modify the class of persons eligible to receive
Awards, (iii) materially increase the benefits accruing to
Participants under the Plan, or (iv) otherwise require stockholder
approval under any applicable law or regulation.
     
     14.2   Termination of Plan
     
     The Company's stockholders or the Board may suspend or terminate
the Plan at any time.  The Plan will have no fixed expiration date;
provided, however, that no Incentive Stock Options may be granted more
than 10 years after the Plan's effective date.
     
     14.3   Consent of Holder
     
     The amendment or termination of the Plan shall not, without the
consent of the Holder of any Award under the Plan, alter or impair any
rights or obligations under any Award theretofore granted under the
Plan.

SECTION 15. GENERAL
     
     15.1   Notification
     
     The Plan Administrator shall promptly notify a Participant of an
Award, and a written grant shall promptly be executed and delivered by
or on behalf of the Company.
     
     15.2   Continued Employment or Services; Rights in Awards
     
     Neither the Plan, participation in the Plan as a Participant nor
any action of the Plan Administrator taken under the Plan shall be
construed as giving any Participant or employee of the Company any
right to be retained in the employ of the Company or limit the
Company's right to terminate the employment or services of the
Participant.
     
     15.3   Registration; Certificates for Shares
     
     The Company shall be under no obligation to any Participant to
register for offering or resale under the Securities Act of 1933, as
amended, or register or qualify under state securities laws, any
shares of Common Stock, security or interest in a security paid or
issued under, or created by, the Plan.  The Company may issue
certificates for shares with such legends and subject to such
restrictions on transfer and stop-transfer instructions as counsel for
                                 15
<PAGE> 87
the Company deems necessary or desirable for compliance by the Company
with federal and state securities laws.
     
     15.4   No Rights as a Stockholder
     
     No Option shall entitle the Holder to any dividend, voting or
other right of a stockholder unless and until the date of issuance
under the Plan of the shares that are the subject of such Awards, free
of all applicable restrictions.
     
     15.5   Compliance With Laws and Regulations
     
     It is the Company's intention that, so long as any of the
Company's equity securities are registered pursuant to Section 12(b)
or 12(g) of the Exchange Act, the Plan shall comply in all respects
with Rule 16b-3 under the Exchange Act and, if any Plan provision is
later found not to be in compliance with such Rule, the provision
shall be deemed null and void, and in all events the Plan shall be
construed in favor of its meeting the requirements of Rule 16b-3.
Notwithstanding anything in the Plan to the contrary, the Board, in
its sole discretion, may bifurcate the Plan so as to restrict, limit
or condition the use of any provision of the Plan to Participants who
are officers or directors subject to Section 16 of the Exchange Act
without so restricting, limiting or conditioning the Plan with respect
to other Participants.  Additionally, in interpreting and applying the
provisions of the Plan, any Option granted as an Incentive Stock
Option pursuant to the Plan shall, to the extent permitted by law, be
construed as an "incentive stock option" within the meaning of
Section 422 of the Code.
     
     15.6   No Trust or Fund
     
     The Plan is intended to constitute an "unfunded" plan.  Nothing
contained herein shall require the Company to segregate any monies or
other property, or shares of Common Stock, or to create any trusts, or
to make any special deposits for any immediate or deferred amounts
payable to any Participant, and no Participant shall have any rights
that are greater than those of a general unsecured creditor of the
Company.
     
     15.7   Severability
     
     If any provision of the Plan or any Award is determined to be
invalid, illegal or unenforceable in any jurisdiction, or as to any
person, or would disqualify the Plan or any Award under any law deemed
applicable by the Plan Administrator, such provision shall be
construed or deemed amended to conform to applicable laws, or, if it
cannot be so construed or deemed amended without, in the Plan
Administrator's determination, materially altering the intent of the
Plan or the Award, such provision shall be stricken as to such
                                16
<PAGE> 88
jurisdiction, person or Award, and the remainder of the Plan and any
such Award shall remain in full force and effect.

SECTION 16. EFFECTIVE DATE
     
     The Plan's effective date is the date on which it is adopted by
the Board, so long as it is approved by the Company's stockholders at
any time within 12 months of such adoption or, if earlier, and to the
extent required for compliance with Rule 16b-3 under the Exchange Act,
at the next annual meeting of the Company's stockholders after
adoption of the Plan by the Board.
     
     Adopted by the Board on May 15, 1995 and approved by the
Company's stockholders on July 18, 1995.  Plan amended and restated by
the Board as of November 7, 1996.
                                  17


<PAGE> 89
                                                         Exhibit 10.11
                                                         of Form 10KSB
                            PROMISSORY NOTE

PrincipalLoan DateMaturityLoan No.    Call CollateralAccount
Officer Initials
$1,000,00009-08-1995                   19     0380 8741855333    21728

Borrower:                     SYNTHETECH, INC.    Lender:   United
States National Bank Of Oregon
        1290 INDUSTRIAL WAY        Mid-Willamette Commercial Banking
Center
        ALBANY, OR 97321           PL-7 Oregon Corporate Loan
Servicing
                                   555 S. W. Oak
                                   Portland, OR 97204

Principal Amount:   $1,000,000.00  Initial Rate: 9.500%     Date of
Note:   September 8, 1995

PROMISE  TO  PAY.  SYNTHETECH, INC. ("Borrower") promises  to  pay  to
United  States National Bank of Oregon ("Lender"), or order, in lawful
money of the United States of America, on demand, the principal amount
of  One Million & 00/100 Dollars ($1,000,000.00) or so much as may  be
outstanding,   together  with  interest  on  the  unpaid   outstanding
principal balance of each advance.  Interest shall be calculated  from
the date of each advance until repayment of each advance.

PAYMENT.   Borrower  will  pay  this loan  immediately  upon  Lender's
demand.   In  addition, Borrower will pay regular monthly payments  of
all  accrued  unpaid interest due as of each payment  date,  beginning
October  5, 1995, with all subsequent interest payments to be  due  on
the  same  day  of each month after that.  Interest on  this  Note  is
computed on a 365/360 simple interest basis; that is, by applying  the
ratio  of the annual interest rate over a year of 360 days, multiplied
by  the outstanding principal balance, multiplied by the actual number
of  days  the  principal balance is outstanding.   Borrower  will  pay
Lender  at  Lender's  address shown above or at such  other  place  as
Lender  may designate in writing.  Unless otherwise agreed or required
by  applicable  law, payments will be applied first to accrued  unpaid
interest,  then to principal, and any remaining amount to  any  unpaid
collection costs and late charges.

VARIABLE INTEREST RATE.  The interest rate on this Note is subject  to
change  from  time to time based on changes in an index which  is  the
Lender's  Prime Rate.  This is the rate of interest which Lender  from
time  to  time establishes as its Prime Rate and is not, for  example,
the lowest rate of interest which Lender collects from any borrower or
class of borrowers (the "Index').  The interest rate shall be adjusted
without notice effective on the day Bank's prime rate changes.  Lender
will  tell  Borrower  the current Index rate upon Borrower's  request.
Borrower  understands that Lender may make loans based on other  rates
as well.  The interest rate change will not occur more often than each
Day.   The Index currently is 8.750% per annum.  The interest rate  to
be  applied to the unpaid principal balance of this Note will be at  a
rate  of  0.750  percentage points over the  Index,  resulting  in  an
initial rate of 9.500% per annum.

PREPAYMENT.   Borrower  agrees that all loan fees  and  other  prepaid
finance  charges are earned fully as of the date of the loan and  will
not be subject to refund upon early payment (whether voluntary or as a
result  of default), except as otherwise required by law.  Except  for
the  foregoing, Borrower may pay without penalty all or a  portion  of
the  amount  owed  earlier than it is due.  Early payments  will  not,
unless  agreed to by Lender in writing, relieve Borrower of Borrower's
obligation  to  continue to make payments of accrued unpaid  interest.
Rather, they will reduce the principal balance due.

DEFAULT.  Borrower will be in default if any of the following happens:
(a)  Borrower falls to make any payment when due. (b) Borrower  breaks
any  promise Borrower has made to Lender, or Borrower fails to perform
promptly at the time and strictly in the manner provided in this  Note
or  any  agreement related to this Note, or in any other agreement  or
loan  Borrower  has with Lender. (c) Any representation  or  statement
made  or  furnished to Lender by Borrower or on Borrower's  behalf  is
false  or  misleading  in any material respect. (d)  Borrower  becomes
insolvent,  a  receiver  is  appointed  for  any  part  of  Borrower's
property,  Borrower makes an assignment for the benefit of  creditors,
or  any proceeding is commenced either by Borrower or against Borrower
under  any  bankruptcy or insolvency laws. (e) Any creditor  tries  to
<PAGE> 90
take  any of Borrower's property on or in which Lender has a  lien  or
security  interest.  This includes a garnishment of any of  Borrower's
accounts with Lender. (f) Any of the events described in this  default
section occurs with respect to any guarantor of this Note. (g)  Lender
in good faith deems itself insecure.

If  any  default, other than a default in payment, is curable  and  if
Borrower has not been given a notice of a breach of the same provision
of  this Note within the preceding twelve (12) months, it may be cured
(and  no  event  of  default will have occurred)  if  Borrower,  after
receiving  written notice from Lender demanding cure of such  default:
(a)  cures  the default within fifteen (15) days; or (b) if  the  cure
requires  more  than  fifteen (15) days, immediately  initiates  steps
which  Lender  deems in Lender's sole discretion to be  sufficient  to
cure the default and thereafter continues and completes all reasonable
and  necessary  steps  sufficient to produce  compliance  as  soon  as
reasonably practical.

LENDER'S  RIGHTS.  Upon default, Lender may declare the entire  unpaid
principal  balance  on  this  Note and  all  accrued  unpaid  interest
immediately  due,  without notice, and then  Borrower  will  pay  that
amount.   Upon default, including failure to pay upon final  maturity,
Lender, at its option, may also, if permitted under applicable law, do
one  or both of the following: (a) increase the variable interest rate
on  this  Note to 5.750 percentage points over the Index, and (b)  add
any  unpaid  accrued  interest to principal and  such  sum  will  bear
interest  therefrom  until  paid at the rate  provided  in  this  Note
(including any increased rate).  The interest rate will not exceed the
maximum  rate  permitted by applicable law.  Lender may  hire  or  pay
someone  else  to  help collect this Note if Borrower  does  not  pay.
Borrower also will pay Lender that amount.  This includes, subject  to
any limits under applicable law, Lender's attorneys' fees and Lender's
legal expenses whether or not there is a lawsuit, including attorneys'
fees  and legal expenses for bankruptcy proceedings (including efforts
to  modify  or vacate any automatic stay or injunction), appeals,  and
any  anticipated post-judgment collection services.  If not prohibited
by applicable law, Borrower also will pay any court costs, in addition
to  all  other sums provided by law.  This Note has been delivered  to
Lender and accepted by Lender in the State of Oregon.  If there  is  a
lawsuit,  Borrower  agrees  upon Lender's request  to  submit  to  the
jurisdiction of the courts of Multnomah County, the State  of  Oregon.
Subject  to the provisions on arbitration, this Note shall be governed
by and construed in accordance with the laws of the State of Oregon.

RIGHT  OF  SETOFF.  Borrower grants to Lender a contractual possessory
security  interest in, and hereby assigns, convoys, delivers, pledges,
and  transfers to Lender all Borrower's right, title and  interest  in
and to, Borrower's accounts with Lender (whether checking, savings, or
some  other  account), including without limitation all accounts  held
jointly  with someone else and all accounts Borrower may open  in  the
future,   excluding  however  all  IRA,  Keogh,  and  trust  accounts.
Borrower authorizes Lender, to the extent permitted by applicable law,
to  charge or setoff all sums owing on this Note against any  and  all
such accounts.

LINE  OF  CREDIT.   This Note evidences a revolving  line  of  credit.
Advances  under  this  Note, as well as directions  for  payment  from
Borrower's accounts, may be requested orally or in writing by Borrower
or  by  an authorized person.  Lender may, but need not, require  that
all  oral  requests be confirmed in writing.  Borrower  agrees  to  be
liable  for  all  sums  either: (a) advanced in  accordance  with  the
instructions  of  an  authorized person or  (b)  credited  to  any  of
Borrower's  accounts with Lender, regardless of the fact that  persons
other  than those authorized to borrow have authority to draw  against
the  accounts.  The unpaid principal balance owing on this Note at any
time  may  be  evidenced by endorsements on this Note or  by  Lender's
internal  records, including daily computer print-outs.   Lender  will
have  no  obligation to advance funds under this Note if: (a) Borrower
or  any  guarantor is in default under the terms of this Note  or  any
agreement  that  Borrower or any guarantor has with Lender,  including
any  agreement made in connection with the signing of this  Note;  (b)
Borrower  or any guarantor ceases doing business or is insolvent;  (c)
any guarantor seeks, claims or otherwise attempts to limit, modify  or
revoke such guarantor's guarantee of this Note or any other loan  with
Lender; (d) Borrower has applied funds provided pursuant to this  Note
for  purposes other than those authorized by Lender; or (e) Lender  in
good  faith  deems  itself  insecure under  this  Note  or  any  other
agreement between Lender and Borrower.

ARBITRATION.  Lender and Borrower agree that all disputes, claims  and
controversies  between them, whether individual, joint,  or  class  in
nature,  arising  from  this  Note  or  otherwise,  including  without
limitation contract and tort disputes, shall be arbitrated pursuant to
the  Rules  of the American Arbitration Association, upon  request  of
<PAGE> 91
either  party.   No act to take or dispose of any collateral  securing
this  Note shall constitute a waiver of this arbitration agreement  or
be  prohibited by this arbitration agreement.  This includes,  without
limitation,  obtaining  injunctive relief or a  temporary  restraining
order;  foreclosing  by notice and sale under any  deed  of  trust  or
mortgage;  obtaining a writ of attachment or imposition of a receiver;
or  exercising  any  rights relating to personal  property,  including
taking  or disposing of such property with or without judicial process
pursuant  to Article 9 of the Uniform Commercial Code.  Any  disputes,
claims,  or  controversies concerning the lawfulness or reasonableness
of  any  act,  or  exercise  of any right, concerning  any  collateral
securing  this  Note,  including any  claim  to  rescind,  reform,  or
otherwise  modify  any agreement relating to the  collateral  securing
this  Note,  shall  also  be  arbitrated,  provided  however  that  no
arbitrator shall have the right or the power to enjoin or restrain any
act  of any party.  Judgment upon any award rendered by any arbitrator
may be entered in any court having jurisdiction.  Nothing in this Note
shall preclude any party from seeking equitable relief from a court of
competent jurisdiction.  The statute of limitations, estoppel, waiver,
laches,  and similar doctrines which would otherwise be applicable  in
an  action  brought by a party shall be applicable in any  arbitration
proceeding, and the commencement of an arbitration proceeding shall be
deemed  the commencement of an action for these purposes.  The Federal
Arbitration  Act shall apply to the construction, interpretation,  and
enforcement of this arbitration provision.

LATE  CHARGE.  If a payment is 19 days or more past due, Borrower will
be charged a late charge of 5% of the delinquent payment.

CREDIT  ACT  -  CHECKING ACCOUNT NUMBER 022-0016-224  LOCATED  AT  THE
ALBANY  COMMUNITY  BRANCH.  Borrower has requested  and  been  granted
Lender's  Commercial  Line of Credit Automatic Cash  Transfer  Service
("Credit ACT").  So long as this Note is in place, Borrower authorizes
Lender  to draw from Borrower's available line of credit and  transfer
funds   automatically  to  Borrower's  commercial   checking   account
described  in  the heading of this paragraph ("Checking  Account")  in
accordance with this section.  So long as this agreement is in  place,
Lender agrees to make an automatic cash transfer from Borrower's  line
of  credit  to its Checking Account in increments of $500.00,  to  pay
checks  that would otherwise overdraw Borrower's Checking  Account  by
$100.00 or more, up to Borrower's available credit limit.  The  amount
of each Credit ACT transfer will be an advance under the terms of this
Note.   There is no charge for using Credit ACT.  Borrower  agrees  to
pay  prevailing overdraft or other applicable checking account charges
then  in effect if an overdraft may not be paid because an ACT in  the
required  increment of $500.00 to pay the full amount of the overdraft
would exceed Borrower's credit limit.  If Borrower's credit limit  has
been  exceeded, and no other ACT privileges are available to Borrower,
any  check  presented for payment from Checking Account will,  at  the
sole  option  of  Lender,  either be paid, thus  overdrawing  Checking
Account, or dishonored.  Lender may change the terms of Credit ACT  at
any  time  by  giving Borrower written notice, sent to the  Borrower's
address  as shown in Lender's records, prior to the effective date  of
the change.

Lender  reserves  the  right to discontinue this service  upon  giving
written  notice  to  the  Borrower, at  Borrower's  address  shown  in
Lender's  records,  under  the  following  circumstances:  (1)  Lender
reasonably  believes  that  Borrower will be  unable  to  fulfill  its
repayment  obligations  because  of  a  material  adverse  change   in
Borrower's  financial circumstances. (2) Borrower  fails  to  promptly
provide  financial information that Lender has requested. (3) Borrower
is  in default of a material provision of any promissory note or  loan
agreement with Lender.

If Lender discontinues further Credit ACT services due to any of these
circumstances,  Lender  will  mail  Borrower  written  notice  of  the
discontinuation and the reasons therefor.  After such notice is given,
Borrower  must  request in writing that its Credit ACT be  reinstated.
Before  Credit ACT privileges are reinstated, Lender may ask  Borrower
to  provide new information, at Borrower's expense.  If Borrower shows
Lender  that the circumstances that caused cancellation of Credit  ACT
services  have  ceased  to exist, Credit ACT  will  be  reinstated  at
Lender's sole option and discretion upon written notice to Borrower.

PERIODIC  REVIEW.  Lender will review the loan periodically.   At  the
time  of  the review, Borrower will furnish Lender with any additional
information  regarding  Borrower's financial  condition  and  business
operations that Lender requests.  This information may include, but is
not limited to, financial statements, tax returns, lists of assets and
liabilities, agings of receivables and payables, inventory  schedules,
budgets   and  forecasts.   If  upon  review,  Lender,  in  its   sole
<PAGE> 92
discretion,  determines that there has been a material adverse  change
in  Borrower's financial condition, Borrower will be in default.  Upon
default, Lender shall have all rights specified herein.

DEMAND NOTE.  BORROWER ACKNOWLEDGES AND AGREES THAT (A) THIS NOTE IS A
DEMAND  NOTE,  AND  LENDER IS ENTITLED TO DEMAND BORROWER'S  IMMEDIATE
PAYMENT  IN FULL OF ALL AMOUNTS OWING HEREUNDER, (B) NEITHER  ANYTHING
TO  THE  CONTRARY  CONTAINED HEREIN OR IN  ANY  OTHER  LOAN  DOCUMENTS
(INCLUDING BUT NOT LIMITED TO, PROVISIONS RELATING TO DEFAULTS, RIGHTS
OF CURE, DEFAULT RATE OF INTEREST, INSTALLMENT PAYMENTS, LATE CHARGES,
PERIODIC REVIEW OF BORROWER'S FINANCIAL CONDITION, AND COVENANTS)  NOR
ANY  ACT  OF  LENDER PURSUANT TO ANY SUCH PROVISIONS  SHALL  LIMIT  OR
IMPAIR LENDER'S RIGHT OR ABILITY TO REQUIRE BORROWER'S PAYMENT IN FULL
OF  ALL AMOUNTS OWING HEREUNDER IMMEDIATELY UPON LENDER'S DEMAND,  AND
(C)  UPON  LENDER  MAKING  ANY  SUCH  DEMAND,  LENDER  SHALL  HAVE  NO
OBLIGATION  TO  MAKE ANY ADVANCE UNDER THIS NOTE  OR  UNDER  THE  LOAN
DOCUMENTS.

GENERAL PROVISIONS.  This Note is payable on demand.  The inclusion of
specific  default  provisions or rights of Lender shall  not  preclude
Lender's right to declare payment of this Note on its demand.   Lender
may  delay or forgo enforcing any of its rights or remedies under this
Note  without losing them.  Borrower and any other person  who  signs,
guarantees or endorses this Note, to the extent allowed by law,  waive
presentment, demand for payment, protest and notice of dishonor.  Upon
any  change in the terms of this Note, and unless otherwise  expressly
stated  in  writing, no party who signs this Note, whether  as  maker,
guarantor,  accommodation maker or endorser, shall  be  released  from
liability.   All  such parties agree that Lender may renew  or  extend
(repeatedly  and  for any length of time) this loan,  or  release  any
party  or guarantor or collateral; or impair, fail to realize upon  or
perfect  Lender's security interest in the collateral;  and  take  any
other  action  deemed necessary by Lender without the  consent  of  or
notice  to anyone.  All such parties also agree that Lender may modify
this  loan without the consent of or notice to anyone other  than  the
party with whom the modification is made.

UNDER OREGON LAW, MOST AGREEMENTS, PROMISES AND COMMITMENTS MADE BY US
(LENDER)  AFTER  OCTOBER  3, 1989 CONCERNING LOANS  AND  OTHER  CREDIT
EXTENSIONS WHICH ARE NOT FOR PERSONAL, FAMILY OR HOUSEHOLD PURPOSES OR
SECURED SOLELY BY THE BORROWER'S RESIDENCE MUST BE IN WRITING, EXPRESS
CONSIDERATION AND BE SIGNED BY US TO BE ENFORCEABLE.

PRIOR  TO  SIGNING  THIS NOTE, BORROWER READ AND  UNDERSTOOD  ALL  THE
PROVISIONS  OF  THIS  NOTE,  INCLUDING  THE  VARIABLE  INTEREST   RATE
PROVISIONS.  BORROWER AGREES TO THE TERMS OF THE NOTE AND ACKNOWLEDGES
RECEIPT OF A COMPLETED COPY OF THE NOTE.

BORROWER:

SYNTHETECH, INC.

X       \s\ Charles B. Williams, VP                    X       \s\
Philip Knutson, VP
     Authorized Officer                      Authorized Officer

LENDER:

United States National Bank of Oregon

By      \s\
     Authorized Officer


<PAGE> 93
                                                         Exhibit 10.12
                                                         of Form 10KSB


                     COMMERCIAL SECURITY AGREEMENT

PrincipalLoan DateMaturityLoan No.    Call CollateralAccount
Officer Initials
$1,000,00009-08-1995                   19     0380 8741855333    21728

Borrower: SYNTHETECH, INC.         Lender:   United States National
Bank of Oregon
          1290 INDUSTRIAL WAY      Mid-Willamette Commercial Banking
Center
          ALBANY, OR 97321              PL-7 Oregon Corporate Loan
Servicing
                                   555 S. W. Oak
                                   Portland, OR 97204


THIS COMMERCIAL SECURITY AGREEMENT is entered into between SYNTHETECH,
INC. (referred to below as "Grantor"); and United States National Bank
of   Oregon   (referred   to   below  as  "Lender").    For   valuable
consideration,  Grantor grants to Lender a security  interest  in  the
Collateral  to  secure the Indebtedness and agrees that  Lender  shall
have  the  rights  stated  in  this  Agreement  with  respect  to  the
Collateral, in addition to all other rights which Lender may  have  by
law.

DEFINITIONS.   The  following words shall have the following  meanings
when  used  in  this Agreement.  Terms not otherwise defined  in  this
Agreement  shall  have the meanings attributed to such  terms  in  the
Uniform Commercial Code.  All references to dollar amounts shall  mean
amounts in lawful money of the United States of America.

     Agreement.   The word "Agreement" means this Commercial  Security
     Agreement,  as this Commercial Security Agreement may be  amended
     or  modified  from time to time, together with all  exhibits  and
     schedules  attached  to this Commercial Security  Agreement  from
     time to time.

     Collateral.  The word "Collateral" means the following  described
     property  of  Grantor, whether now owned or  hereafter  acquired,
     whether now existing or hereafter arising, and wherever located:

          All  chattel  paper, accounts, contract rights  and  general
     intangibles

     In  addition,  the word "Collateral" includes all the  following,
     whether now owned or hereafter acquired, whether now existing  or
     hereafter arising, and wherever located:

     (a)  All accessions, accessories, increases, and additions to and
     all  replacements of and substitutions for any property described
     above.

     (b)  All products and produce of any of the property described in
     this Collateral section.

     (c)    All   accounts,  contract  rights,  general   intangibles,
     instruments,  rents,  monies, payments,  and  all  other  rights,
     arising out of a sale, lease, or other disposition of any of  the
     property described in this Collateral section.

     (d)   All proceeds (including insurance proceeds) from the  sale,
     destruction,  loss, or other disposition of any of  the  property
     described in this Collateral section.

     (e)   All  records  and  data relating to  any  of  the  property
     described  in this Collateral section, whether in the form  of  a
     writing, photograph, microfilm, microfiche, or electronic  media,
     together with all of Grantor's right, title, and interest in  and
<PAGE> 94
     to  all  computer software required to utilize, create, maintain,
     and process any such records or data on electronic media.

     Event  of Default.  The words "Event of Default" mean and include
     without  limitation any of the Events of Default set forth  below
     in the section titled "Events of Default."

     Grantor.    The  word  "Grantor"  means  SYNTHETECH,  INC.,   its
     successors and assigns

     Guarantor.   The  word  "Guarantor" means  and  includes  without
     limitation  each  and  all  of  the  guarantors,  sureties,   and
     accommodation parties in connection with the Indebtedness.

     Indebtedness.   The  word "Indebtedness" means  the  indebtedness
     evidenced  by  the  Note, including all principal  and  interest,
     together  with all other indebtedness and costs and expenses  for
     which Grantor is responsible under this Agreement or under any of
     the  Related  Documents.   In addition, the  word  "Indebtedness"
     includes  all  other  obligations, debts  and  liabilities,  plus
     interest  thereon, of Grantor, or any one or  more  of  them,  to
     Lender, as well as all claims by Lender against Grantor,  or  any
     one  or more of them, whether existing now or later; whether they
     are voluntary or involuntary, due or not due, direct or indirect,
     absolute  or  contingent,  liquidated  or  unliquidated;  whether
     Grantor  may  be  liable  individually or  jointly  with  others;
     whether   Grantor   may  be  obligated  as   guarantor,   surety,
     accommodation  party  or otherwise; whether  recovery  upon  such
     indebtedness may be or hereafter may become barred by any statute
     of limitations; and whether such indebtedness may be or hereafter
     may become otherwise unenforceable.

     Lender.   The word "Lender" means United States National Bank  of
     Oregon, its successors and assigns.

     Note.   The word "Note" means the note or credit agreement  dated
     September 8, 1995, in the principal amount of $1,000,000.00  from
     Grantor to Lender, together with all renewals of, extensions  of,
     modifications   of,  refinancings  of,  consolidations   of   and
     substitutions for the note or credit agreement.

     Related  Documents.   The  words  "Related  Documents"  mean  and
     include   without   limitation  all  promissory   notes,   credit
     agreements,    loan    agreements,   environmental    agreements,
     guaranties, security agreements, mortgages, deeds of  trust,  and
     all  other instruments, agreements and documents, whether now  or
     hereafter existing, executed in connection with the Indebtedness.

RIGHT   OF   SETOFF.   Grantor  hereby  grants  Lender  a  contractual
possessory security interest in and hereby assigns, conveys, delivers,
pledges,  and transfers all of Grantor's right, title and interest  in
and  to Grantor's accounts with Lender (whether checking, savings,  or
some  other account), including all accounts held jointly with someone
else  and  all  accounts  Grantor may open in  the  future,  excluding
however  all  IRA,  Keogh,  and  trust accounts.   Grantor  authorizes
Lender, to the extent permitted by applicable law, to charge or setoff
all Indebtedness against any and all such accounts.

OBLIGATIONS OF GRANTOR.  Grantor warrants and covenants to  Lender  as
follows:

     Organization.  Grantor is a corporation which is duly  organized,
     validly  existing, and in good standing under  the  laws  of  the
     state   of  Grantor's  incorporation.   Grantor  has  its   chief
     executive  office  at  1290 INDUSTRIAL  WAY,  ALBANY,  OR  97321.
     Grantor  will  notify Lender of any change  in  the  location  of
     Grantor's chief executive office.

     Authorization.  The execution, delivery, and performance of  this
     Agreement  by Grantor have been duly authorized by all  necessary
     action by Grantor and do not conflict with, result in a violation
     of,  or  constitute  a  default under (a) any  provision  of  its
     articles  of  incorporation or organization, or  bylaws,  or  any
     agreement  or other instrument binding upon Grantor  or  (b)  any
     law,  governmental regulation, court decree, or order  applicable
     to Grantor.
<PAGE> 95
     Perfection of Security Interest.  Grantor agrees to execute  such
     financing  statements  and  to take whatever  other  actions  are
     requested  by  Lender to perfect and continue  Lender's  security
     interest in the Collateral.  Upon request of Lender, Grantor will
     deliver  to  Lender  any and all of the documents  evidencing  or
     constituting  the  Collateral, and  Grantor  will  note  Lender's
     interest  upon  any  and all chattel paper if  not  delivered  to
     Lender  for possession by Lender.  Grantor hereby appoints Lender
     as  its irrevocable attorney-in-fact for the purpose of executing
     any  documents necessary to perfect or to continue  the  security
     interest granted in this Agreement.  Lender may at any time,  and
     without  further  authorization  from  Grantor,  file  a  carbon,
     photographic or other reproduction of any financing statement  or
     of this Agreement for use as a financing statement.  Grantor will
     reimburse  Lender  for all expenses for the  perfection  and  the
     continuation of the perfection of Lender's security  interest  in
     the  Collateral.  Grantor promptly will notify Lender before  any
     change  in  Grantor's name including any change  to  the  assumed
     business  names  of  Grantor.   This  is  a  continuing  Security
     Agreement and will continue in effect even though all or any part
     of  the Indebtedness is paid in full and even though for a period
     of time Grantor may not be indebted to Lender.

     No  Violation.  The execution and delivery of this Agreement will
     not  violate any law or agreement governing Grantor or  to  which
     Grantor   is  a  party,  and  its  certificate  or  articles   of
     incorporation and bylaws do not prohibit any term or condition of
     this Agreement.

     Enforceability  of  Collateral.  To  the  extent  the  Collateral
     consists of accounts, contract rights, chattel paper, or  general
     intangibles, the Collateral is enforceable in accordance with its
     terms,  is  genuine, and complies with applicable laws concerning
     form,  content and manner of preparation and execution,  and  all
     persons  appearing  to  be  obligated  on  the  Collateral   have
     authority  and capacity to contract and are in fact obligated  as
     they  appear  to be on the Collateral.  At the time  any  account
     becomes  subject to a security interest in favor of  Lender,  the
     account  shall  be  a  good  and valid  account  representing  an
     undisputed,  bona  fide  indebtedness  incurred  by  the  account
     debtor, for merchandise held subject to delivery instructions  or
     theretofore shipped or delivered pursuant to a contract of  sale,
     or  for services theretofore performed by Grantor with or for the
     account  debtor;  there  shall  be no  setoffs  or  counterclaims
     against  any  such  account;  and no agreement  under  which  any
     deductions or discounts may be claimed shall have been made  with
     the account debtor except those disclosed to Lender in writing.

     Removal of Collateral.  Grantor shall keep the Collateral (or  to
     the extent the Collateral consists of intangible property such as
     accounts,  the  records concerning the Collateral)  at  Grantor's
     address shown above, or at such other locations as are acceptable
     to  Lender.   Except  in  the ordinary course  of  its  business,
     including  the sales of inventory, Grantor shall not  remove  the
     Collateral from its existing locations without the prior  written
     consent of Lender.  To the extent that the Collateral consists of
     vehicles,  or other titled property, Grantor shall  not  take  or
     permit   any   action   which  would  require   application   for
     certificates  of  title for the vehicles  outside  the  State  of
     Oregon, without the prior written consent of Lender.

     Transactions Involving Collateral.  Except for inventory sold  or
     accounts  collected in the ordinary course of Grantor's business,
     Grantor  shall not sell, offer to sell, or otherwise transfer  or
     dispose  of the Collateral.  Grantor shall not pledge,  mortgage,
     encumber or otherwise permit the Collateral to be subject to  any
     lien,  security interest, encumbrance, or charge, other than  the
     security  interest  provided for in this Agreement,  without  the
     prior   written  consent  of  Lender.   This  includes   security
     interests  even  if  junior in right to  the  security  interests
     granted  under  this  Agreement.  Unless waived  by  Lender,  all
     proceeds  from  any disposition of the Collateral  (for  whatever
     reason)  shall  be  held in trust for Lender  and  shall  not  be
     commingled   with  any  other  funds;  provided   however,   this
     requirement shall not constitute consent by Lender to any sale or
     other  disposition.   Upon  receipt,  Grantor  shall  immediately
     deliver any such proceeds to Lender.

     Title.   Grantor represents and warrants to Lender that it  holds
     good  and  marketable title to the Collateral, free and clear  of
     all liens and encumbrances except for the lien of this Agreement.
<PAGE> 96
     No  financing statement covering any of the Collateral is on file
     in  any public office other than those which reflect the security
     interest  created  by  this Agreement  or  to  which  Lender  has
     specifically consented.  Grantor shall defend Lender's rights  in
     the  Collateral  against  the claims and  demands  of  all  other
     persons.

     Collateral  Schedules and Locations.  As often  as  Lender  shall
     require,  and insofar as the Collateral consists of accounts  and
     general intangibles, Grantor shall deliver to Lender schedules of
     such  Collateral,  including  such  information  as  Lender   may
     require,  including  without limitation names  and  addresses  of
     account  debtors and agings of accounts and general  intangibles.
     Such  information shall be submitted for Grantor and each of  its
     subsidiaries or related companies.

     Maintenance and Inspection of Collateral.  Grantor shall maintain
     all  tangible  Collateral in good condition and repair.   Grantor
     will  not  commit  or  permit damage to  or  destruction  of  the
     Collateral  or  any  part  of  the Collateral.   Lender  and  its
     designated representatives and agents shall have the right at all
     reasonable  times to examine, inspect, and audit  the  Collateral
     wherever located.  Grantor shall immediately notify Lender of all
     cases  involving  the  return, rejection, repossession,  loss  or
     damage  of  or  to any Collateral; of any request for  credit  or
     adjustment  or of any other dispute arising with respect  to  the
     Collateral; and generally of all happenings and events  affecting
     the Collateral or the value or the amount of the Collateral.

     Taxes,  Assessments and Liens.  Grantor will  pay  when  due  all
     taxes,  assessments  and liens upon the Collateral,  its  use  or
     operation, upon this Agreement, upon any promissory note or notes
     evidencing  the  Indebtedness, or upon any of the  other  Related
     Documents.  Grantor may withhold any such payment or may elect to
     contest  any  lien  if  Grantor is in good  faith  conducting  an
     appropriate proceeding to contest the obligation to  pay  and  so
     long as Lender's interest in the Collateral is not jeopardized in
     Lender's sole opinion.  If the Collateral is subjected to a  lien
     which  is not discharged within fifteen (15) days, Grantor  shall
     deposit  with Lender cash, a sufficient corporate surety bond  or
     other  security satisfactory to Lender in an amount  adequate  to
     provide  for the discharge of the lien plus any interest,  costs,
     attorneys' fees or other charges that could accrue as a result of
     foreclosure  or  sale of the Collateral.  In any contest  Grantor
     shall  defend  itself  and  Lender and shall  satisfy  any  final
     adverse  judgment  before  enforcement  against  the  Collateral.
     Grantor  shall  name Lender as an additional  obligee  under  any
     surety bond furnished in the contest proceedings.

     Compliance With Governmental Requirements.  Grantor shall  comply
     promptly with all laws, ordinances, rules and regulations of  all
     governmental authorities, now or hereafter in effect,  applicable
     to   the  ownership,  production,  disposition,  or  use  of  the
     Collateral.   Grantor  may contest in good faith  any  such  law,
     ordinance  or  regulation  and  withhold  compliance  during  any
     proceeding,  including appropriate appeals, so long  as  Lender's
     interest  in  the  Collateral,  in  Lender's  opinion,   is   not
     jeopardized.

     Hazardous Substances.  Grantor represents and warrants  that  the
     Collateral  never has been, and never will be  so  long  as  this
     Agreement  remains  a  lien  on  the  Collateral,  used  for  the
     generation,  manufacture,  storage,  transportation,   treatment,
     disposal, release or threatened release of any hazardous waste or
     substance,  as  those  terms  are defined  in  the  Comprehensive
     Environmental Response, Compensation, and Liability Act of  1980,
     as  amended,  42  U.S.C. Section 9601, et  seq.  ("CERCLA"),  the
     Superfund  Amendments and Reauthorization Act of  1986,  Pub.  L.
     No.  99-499 ("SARA"), the Hazardous Materials Transportation Act,
     49  U.S.C.  Section 1801, et seq., the Resource Conservation  and
     Recovery  Act,  49  U.S.C.  Section  6901,  et  seq.,  or   other
     applicable  state or Federal laws, rules, or regulations  adopted
     pursuant  to  any of the foregoing or intended to  protect  human
     health  or  the  environment ("Environmental Laws").   The  terms
     "hazardous  waste" and "hazardous substance" shall also  include,
     without  limitation, petroleum and petroleum by-products  or  any
     fraction   thereof   and  asbestos.   The   representations   and
     warranties contained herein are based on Grantor's due  diligence
     in   investigating  the  Collateral  for  hazardous  wastes   and
     substances.   Grantor hereby (a) releases and waives  any  future
     claims against Lender for indemnity or contribution in the  event
     Grantor  becomes  liable for cleanup or  other  costs  under  any
     Environmental Laws, and (b) agrees to indemnify and hold harmless
<PAGE> 97
     Lender  against  any and all claims and losses resulting  from  a
     breach of this provision of this Agreement, or as a result  of  a
     violation   of  any  Environmental  Laws.   This  obligation   to
     indemnify shall survive the payment of the Indebtedness  and  the
     satisfaction of this Agreement.

     Maintenance  of  Casualty Insurance.  Grantor shall  procure  and
     maintain all risks insurance, including without limitation  fire,
     theft  and  liability coverage together with such other insurance
     as  Lender may require with respect to the Collateral,  in  form,
     amounts, coverages and basis reasonably acceptable to Lender  and
     issued by a company or companies reasonably acceptable to Lender.
     Grantor, upon request of Lender, will deliver to Lender from time
     to  time  the  policies  or certificates  of  insurance  in  form
     satisfactory  to  Lender, including stipulations  that  coverages
     will  not  be cancelled or diminished without at least  ten  (10)
     days'  prior  written  notice to Lender  and  not  including  any
     disclaimer of the insurer's liability for failure to give such  a
     notice.   Each insurance policy also shall include an endorsement
     providing  that coverage in favor of Lender will not be  impaired
     in  any  way  by any act, omission or default of Grantor  or  any
     other person.  In connection with all policies covering assets in
     which  Lender  holds or is offered a security  interest,  Grantor
     will  provide Lender with such loss payable or other endorsements
     as Lender may require.  If Grantor at any time fails to obtain or
     maintain  any insurance as required under this Agreement,  Lender
     may  (but  shall  not be obligated to) obtain such  insurance  as
     Lender  deems  appropriate, including if it  so  chooses  "single
     interest  insurance," which will cover only Lender's interest  in
     the Collateral.

     Application of Insurance Proceeds.  Grantor shall promptly notify
     Lender of any loss or damage to the Collateral.  Lender may  make
     proof of loss if Grantor fails to do so within fifteen (15)  days
     of   the  casualty.   All  proceeds  of  any  insurance  on   the
     Collateral, including accrued proceeds thereon, shall be held  by
     Lender  as part of the Collateral.  If Lender consents to  repair
     or  replacement  of  the damaged or destroyed Collateral,  Lender
     shall,  upon satisfactory proof of expenditure, pay or  reimburse
     Grantor  from the proceeds for the reasonable cost of  repair  or
     restoration. If Lender does not consent to repair or  replacement
     of the Collateral, Lender shall retain a sufficient amount of the
     proceeds  to  pay  all of the Indebtedness,  and  shall  pay  the
     balance  to Grantor.  Any proceeds which have not been  disbursed
     within  six (6) months after their receipt and which Grantor  has
     not  committed  to  the repair or restoration of  the  Collateral
     shall be used to prepay the Indebtedness.

     Insurance Reserves.  Lender may require Grantor to maintain  with
     Lender reserves for payment of insurance premiums, which reserves
     shall  be  created  by monthly payments from  Grantor  of  a  sum
     estimated by Lender to be sufficient to produce, at least fifteen
     (15) days before the premium due date, amounts at least equal  to
     the  insurance premiums to be paid.  If fifteen (15) days  before
     payment is due, the reserve funds are insufficient, Grantor shall
     upon  demand  pay  any deficiency to Lender.  The  reserve  funds
     shall be held by Lender as a general deposit and shall constitute
     a  non-interest-bearing  account  which  Lender  may  satisfy  by
     payment  of the insurance premiums required to be paid by Grantor
     as  they  become due.  Lender does not hold the reserve funds  in
     trust  for  Grantor, and Lender is not the agent of  Grantor  for
     payment of the insurance premiums required to be paid by Grantor.
     The  responsibility  for  the payment of  premiums  shall  remain
     Grantor's sole responsibility.

     Insurance  Reports.   Grantor,  upon  request  of  Lender,  shall
     furnish  to  Lender reports on each existing policy of  insurance
     showing   such  information  as  Lender  may  reasonably  request
     including  the  following: (a) the name of the insurer;  (b)  the
     risks  insured;  (c) the amount of the policy; (d)  the  property
     insured;  (e)  the  then  current value on  the  basis  of  which
     insurance  has  been obtained and the manner of determining  that
     value;  and (f) the expiration date of the policy.  In  addition,
     Grantor shall upon request by Lender (however not more often than
     annually)  have an independent appraiser satisfactory  to  Lender
     determine, as applicable, the cash value or replacement  cost  of
     the Collateral.

GRANTOR'S RIGHT TO POSSESSION AND TO COLLECT ACCOUNTS.  Until  default
and  except  as otherwise provided below with respect to accounts  and
above  in  the  paragraph titled "Transactions Involving  Collateral",
Grantor  may  have  possession of the tangible personal  property  and
<PAGE> 98
beneficial  use  of all the Collateral and may use it  in  any  lawful
manner  not inconsistent with this Agreement or the Related Documents,
provided  that Grantor's right to possession and beneficial use  shall
not  apply  to  any Collateral where possession of the  Collateral  by
Lender  is  required by law to perfect Lender's security  interest  in
such  Collateral.   Until otherwise notified by  Lender,  Grantor  may
collect any of the Collateral consisting of accounts.  At any time and
even though no Event of Default exists, Lender may exercise its rights
to collect the accounts and to notify account debtors to make payments
directly to Lender for application to the Indebtedness.  If Lender  at
any time has possession of any Collateral, whether before or after  an
Event  of Default, Lender shall be deemed to have exercised reasonable
care in the custody and preservation of the Collateral if Lender takes
such action for that purpose as Grantor shall request or as Lender, in
Lender's   sole   discretion,  shall  deem   appropriate   under   the
circumstances, but failure to honor any request by Grantor  shall  not
of  itself  be  deemed  to be a failure to exercise  reasonable  care.
Lender  shall not be required to take any steps necessary to  preserve
any  rights  in the Collateral against prior parties, nor to  protect,
preserve  or  maintain  any  security interest  given  to  secure  the
Indebtedness.

EXPENDITURES  BY LENDER.  If not discharged or paid when  due,  Lender
may  (but  shall  not be obligated to) discharge or  pay  any  amounts
required  to  be  discharged or paid by Grantor under this  Agreement,
including  without  limitation all taxes, liens,  security  interests,
encumbrances,  and other claims, at any time levied or placed  on  the
Collateral.  Lender also may (but shall not be obligated to)  pay  all
costs  for  insuring, maintaining and preserving the Collateral.   All
such  expenditures incurred or paid by Lender for such  purposes  will
then  bear interest at the rate charged under the Note from  the  date
incurred  or paid by Lender to the date of repayment by Grantor.   All
such expenses shall become a part of the Indebtedness and, at Lender's
option, will (a) be payable on demand, (b) be added to the balance  of
the  Note and be apportioned among and be payable with any installment
payments  to  become due during either (i) the term of any  applicable
insurance  policy or (ii) the remaining term of the Note,  or  (c)  be
treated  as  a  balloon payment which will be due and payable  at  the
Note's  maturity.   This Agreement also will secure payment  of  these
amounts.   Such  right shall be in addition to all  other  rights  and
remedies  to  which Lender may be entitled upon the occurrence  of  an
Event of Default.

EVENTS OF DEFAULT.  Each of the following shall constitute an Event of
Default under this Agreement:

     Default  on Indebtedness.  Failure of Grantor to make any payment
     when due on the Indebtedness.

     Other  Defaults.  Failure of Grantor to comply with or to perform
     any  other  term, obligation, covenant or condition contained  in
     this Agreement or in any of the Related Documents or in any other
     agreement between Lender and Grantor.

     Insolvency.    The  dissolution  or  termination   of   Grantor's
     existence  as  a going business, the insolvency of  Grantor,  the
     appointment of a receiver for any part of Grantor's property, any
     assignment  for  the benefit of creditors, any type  of  creditor
     workout,  or  the  commencement  of  any  proceeding  under   any
     bankruptcy or insolvency laws by or against Grantor.

     Creditor  or Forfeiture Proceedings.  Commencement of foreclosure
     or  forfeiture proceedings, whether by judicial proceeding, self-
     help,  repossession  or  any other method,  by  any  creditor  of
     Grantor  or by any governmental agency against the Collateral  or
     any other collateral securing the Indebtedness.  This includes  a
     garnishment  of  any of Grantor's deposit accounts  with  Lender.
     However, this Event of Default shall not apply if there is a good
     faith dispute by Grantor as to the validity or reasonableness  of
     the  claim  which  is  the  basis of the creditor  or  forfeiture
     proceeding  and  if Grantor gives Lender written  notice  of  the
     creditor or forfeiture proceeding and deposits with Lender monies
     or a surety bond for the creditor or forfeiture proceeding, in an
     amount determined by Lender, in its sole discretion, as being  an
     adequate reserve or bond for the dispute.

     Events  Affecting Guarantor.  Any of the preceding events  occurs
     with  respect to any Guarantor of any of the Indebtedness or such
     Guarantor  dies or becomes incompetent.  Lender, at  its  option,
     may,  but shall not be required to, permit the Guarantor's estate
     to  assume  unconditionally  the obligations  arising  under  the
     guaranty  in a manner satisfactory to Lender, and, in  doing  so,
     cure the Event of Default.
<PAGE> 99
     Insecurity.  Lender, in good faith, deems itself insecure.

RIGHTS AND REMEDIES ON DEFAULT.  If an Event of Default occurs under
this Agreement, at any time thereafter, Lender shall have all the
rights of a secured party under the Oregon Uniform Commercial Code.
In addition and without limitation, Lender may exercise any one or
more of the following rights and remedies:

     Accelerate   Indebtedness.   Lender  may   declare   the   entire
     Indebtedness,  including  any prepayment  penalty  which  Grantor
     would  be  required to pay, immediately due and payable,  without
     notice.

     Assemble  Collateral.  Lender may require Grantor to  deliver  to
     Lender  all  or  any portion of the Collateral and  any  and  all
     certificates  of  title  and  other  documents  relating  to  the
     Collateral.    Lender  may  require  Grantor  to   assemble   the
     Collateral  and  make it available to Lender at  a  place  to  be
     designated by Lender.  Lender also shall have full power to enter
     upon the property of Grantor to take possession of and remove the
     Collateral.   If the Collateral contains other goods not  covered
     by  this  Agreement at the time of repossession,  Grantor  agrees
     Lender  may  take  such other goods, provided that  Lender  makes
     reasonable efforts to return them to Grantor after repossession.

     Sell  the  Collateral.  Lender shall have  full  power  to  sell,
     lease,  transfer,  or  otherwise  deal  with  the  Collateral  or
     proceeds thereof in its own name or that of Grantor.  Lender  may
     sell  the  Collateral at public auction or private sale.   Unless
     the Collateral threatens to decline speedily in value or is of  a
     type  customarily sold on a recognized market, Lender  will  give
     Grantor  reasonable notice of the time after  which  any  private
     sale or any other intended disposition of the Collateral is to be
     made unless Grantor has signed, after an Event of Default occurs,
     a   statement   renouncing  or  modifying  Grantor's   right   to
     notification  of  sale.  The requirements  of  reasonable  notice
     shall  be  met  if such notice is given at least  ten  (10)  days
     before  the  time  of  the  sale or  disposition.   All  expenses
     relating to the disposition of the Collateral, including  without
     limitation the expenses of retaking, holding, insuring, preparing
     for  sale and selling the Collateral, shall become a part of  the
     Indebtedness  secured by this Agreement and shall be  payable  on
     demand,  with interest at the Note rate from date of  expenditure
     until repaid.

     Appoint  Receiver.   To the extent permitted by  applicable  law,
     Lender shall have the following rights and remedies regarding the
     appointment  of  a  receiver:  (a) Lender  may  have  a  receiver
     appointed  as  a  matter of right, (b) the  receiver  may  be  an
     employee  of Lender and may serve without bond, and (c) all  fees
     of  the receiver and his or her attorney shall become pad of  the
     Indebtedness  secured by this Agreement and shall be  payable  on
     demand,  with interest at the Note rate from date of  expenditure
     until repaid.

     Collect  Revenues,  Apply  Accounts.  Lender,  either  itself  or
     through a receiver, may collect the payments, rents, income,  and
     revenues  from  the Collateral.  Lender may at any  time  in  its
     discretion transfer any Collateral into its own name or  that  of
     its nominee and receive the payments, rents, income, and revenues
     therefrom  and hold the same as security for the Indebtedness  or
     apply  it  to  payment  of  the Indebtedness  in  such  order  of
     preference  as  Lender may determine.  Insofar as the  Collateral
     consists  of  accounts, general intangibles, insurance  policies,
     instruments,  chattel  paper,  choses  in  action,   or   similar
     property,  Lender  may  demand,  collect,  receipt  for,  settle,
     compromise,  adjust,  sue  for,  foreclose,  or  realize  on  the
     Collateral  as Lender may determine, whether or not  indebtedness
     or  Collateral is then due.  For these purposes, Lender  may,  on
     behalf  of and in the name of Grantor, receive, open and  dispose
     of  mail  addressed to Grantor; change any address to which  mail
     and  payments are to be sent; and endorse notes, checks,  drafts,
     money   orders,  documents  of  title,  instruments   and   items
     pertaining  to  payment, shipment, or storage of any  Collateral.
     To  facilitate collection, Lender may notify account debtors  and
     obligors on any Collateral to make payments directly to Lender.

     Obtain  Deficiency.  If Lender chooses to sell any or all of  the
     Collateral, Lender may obtain a judgment against Grantor for  any
     deficiency  remaining on the Indebtedness  due  to  Lender  after
<PAGE> 100     
     application  of  all amounts received from the  exercise  of  the
     rights provided in this Agreement.  Grantor shall be liable for a
     deficiency  even if the transaction described in this  subsection
     is a sale of accounts or chattel paper.

     Other Rights and Remedies.  Lender shall have all the rights  and
     remedies  of  a  secured  creditor under the  provisions  of  the
     Uniform Commercial Code, as may be amended from time to time.  In
     addition,  Lender shall have and may exercise any  or  all  other
     rights  and remedies it may have available at law, in equity,  or
     otherwise.

     Cumulative  Remedies.   All  of  Lender's  rights  and  remedies,
     whether  evidenced by this Agreement or the Related Documents  or
     by  any  other writing, shall be cumulative and may be  exercised
     singularly  or  concurrently.  Election by Lender to  pursue  any
     remedy  shall  not exclude pursuit of any other  remedy,  and  an
     election  to  make expenditures or to take action to  perform  an
     obligation  of  Grantor  under this  Agreement,  after  Grantor's
     failure to perform, shall not affect Lender's right to declare  a
     default and to exercise its remedies.

MISCELLANEOUS PROVISIONS.  The following miscellaneous provisions are
a part of this Agreement:

     Amendments.  This Agreement, together with any Related Documents,
     constitutes the entire understanding and agreement of the parties
     as  to the matters set forth in this Agreement.  No alteration of
     or amendment to this Agreement shall be effective unless given in
     writing  and signed by the party or parties sought to be  charged
     or bound by the alteration or amendment.

     Applicable Law.  This Agreement has been delivered to Lender  and
     accepted  by  Lender  in  the State of Oregon.   If  there  is  a
     lawsuit,  Grantor agrees upon Lender's request to submit  to  the
     jurisdiction of the courts of Multnomah County, State of  Oregon.
     Subject to the provisions on arbitration, this Agreement shall be
     governed  by  and construed in accordance with the  laws  of  the
     State of Oregon.

     Attorneys' Fees; Expenses.  Grantor agrees to pay upon demand all
     of  Lender's  costs and expenses, including attorneys'  fees  and
     Lender's   legal  expenses,  incurred  in  connection  with   the
     enforcement  of this Agreement.  Lender may pay someone  else  to
     help enforce this Agreement, and Grantor shall pay the costs  and
     expenses  of  such  enforcement.   Costs  and  expenses   include
     Lender's attorneys' fees and legal expenses whether or not  there
     is  a  lawsuit, including attorneys' fees and legal expenses  for
     bankruptcy proceedings (and including efforts to modify or vacate
     any  automatic stay or injunction), appeals, and any  anticipated
     post-judgment  collection services.  Grantor also shall  pay  all
     court  costs and such additional fees as may be directed  by  the
     court.

     Caption  Headings.   Caption headings in this Agreement  are  for
     convenience purposes only and are not to be used to interpret  or
     define the provisions of this Agreement.

     Multiple  Parties;  Corporate  Authority.   All  obligations   of
     Grantor under this Agreement shall be joint and several, and  all
     references  to  Grantor shall mean each and every Grantor.   This
     means  that each of the persons signing below is responsible  for
     all obligations in this Agreement.

     Notices.   All notices required to be given under this  Agreement
     shall  be  given in writing and shall be effective when  actually
     delivered   or  when  deposited  with  a  nationally   recognized
     overnight  courier or deposited in the United States mail,  first
     class, postage prepaid, addressed to the party to whom the notice
     is  to be given at the address shown above.  Any party may change
     its  address  for notices under this Agreement by  giving  formal
     written  notice to the other parties, specifying that the purpose
     of  the  notice is to change the party's address.  To the  extent
     permitted  by applicable law, if there is more than one  Grantor,
     notice  to  any  Grantor will constitute notice to all  Grantors.
     For  notice  purposes, Grantor agrees to keep Lender informed  at
     all times of Grantor's current address(es).
<PAGE> 101
     Power  of  Attorney.  Grantor hereby appoints Lender as its  true
     and  lawful  attorney-in-fact, irrevocably, with  full  power  of
     substitution  to  do  the  following:  (a)  to  demand,  collect,
     receive, receipt for, sue and recover all sums of money or  other
     property which may now or hereafter become due, owing or  payable
     from the Collateral; (b) to execute, sign and endorse any and all
     claims, instruments, receipts, checks, drafts or warrants  issued
     in  payment  for the Collateral; (c) to settle or compromise  any
     and  all  claims arising under the Collateral, and, in the  place
     and  stead  of  Grantor, to execute and deliver its  release  and
     settlement for the claim; and (d) to file any claim or claims  or
     to  take any action or institute or take part in any proceedings,
     either  in  its own name or in the name of Grantor, or otherwise,
     which  in  the  discretion of Lender may seem to be necessary  or
     advisable.  This power is given as security for the Indebtedness,
     and  the  authority hereby conferred is and shall be  irrevocable
     and  shall  remain  in full force and effect until  renounced  by
     Lender.

     Preference  Payments.   Any  monies Lender  pays  because  of  an
     asserted preference claim in Borrower's bankruptcy will become  a
     part  of  the  Indebtedness  and, at Lender's  option,  shall  be
     payable  by  Borrower as provided above in the  "EXPENDITURES  BY
     LENDER" paragraph.

     Severability.   If  a court of competent jurisdiction  finds  any
     provision of this Agreement to be invalid or unenforceable as  to
     any  person  or circumstance, such finding shall not render  that
     provision  invalid or unenforceable as to any  other  persons  or
     circumstances.   If feasible, any such offending provision  shall
     be   deemed   to  be  modified  to  be  within  the   limits   of
     enforceability  or validity; however, if the offending  provision
     cannot  be  so  modified,  it shall be  stricken  and  all  other
     provisions  of this Agreement in all other respects shall  remain
     valid and enforceable.

     Successor Interests.  Subject to the limitations set forth  above
     on  transfer of the Collateral, this Agreement shall  be  binding
     upon  and  inure to the benefit of the parties, their  successors
     and assigns.

     Waiver.   Lender  shall not be deemed to have waived  any  rights
     under  this Agreement unless such waiver is given in writing  and
     signed by Lender.  No delay or omission on the part of Lender  in
     exercising any right shall operate as a waiver of such  right  or
     any  other  right.   A waiver by Lender of a  provision  of  this
     Agreement shall not prejudice or constitute a waiver of  Lender's
     right  otherwise to demand strict compliance with that  provision
     or  any  other provision of this Agreement.  No prior  waiver  by
     Lender,  nor  any course of dealing between Lender  and  Grantor,
     shall constitute a waiver of any of Lender's rights or of any  of
     Grantor's  obligations  as to any future transactions.   Whenever
     the  consent  of  Lender is required under  this  Agreement,  the
     granting  of  such  consent by Lender in any instance  shall  not
     constitute continuing consent to subsequent instances where  such
     consent  is required and in all cases such consent may be granted
     or withheld in the sole discretion of Lender.


<PAGE> 102
                                                         Exhibit 10.13
                                                         of Form 10KSB
                                                                      
                       CHANGE IN TERMS AGREEMENT


PrincipalLoan DateMaturityLoan No.    Call CollateralAccount
Officer Initials
$1,000,000                26   019    355  874185533311267

Borrower:                     SYNTHETECH, INC.    Lender:   United
States National Bank Of Oregon
        1290 INDUSTRIAL WAY        Salem Business Banking Center
        ALBANY, OR 97321           PL-7 Oregon Corporate Loan
Servicing
                                   555 S. W. Oak
                                   Portland, OR 97204

Principal Amount:   $1,000,000.00            Date of Agreement:
September 12, 1996


DESCRIPTION  OF  EXISTING  INDEBTEDNESS.  A  PROMISSORY  NOTE  IN  THE
ORIGINAL  AMOUNT  OF  $1,000,000.00  DATED  SEPTEMBER  8,  1995,  WITH
INTEREST  AT  THE  RATE  OF THE LENDER'S PRIME  PLUS  .750  PERCENTAGE
POINTS, DUE ON DEMAND.

DESCRIPTION  OF  CHANGE  IN  TERMS.  FOR VALUABLE  CONSIDERATION,  THE
BORROWER  AND  LENDER  HEREBY AGREE THAT THE TERMS  OF  THE  NOTE  ARE
CHANGED AS FOLLOWS:  EFFECTIVE SEPTEMBER 12, 1996 THE INTEREST RATE IS
CHANGED  IN ACCORDANCE WITH THE TERMS AS SHOWN BELOW IN THE  "VARIABLE
INTERST RATE" SECTION OF THIS NOTE.

PROMISE  TO  PAY.  SYNTHETECH, INC. ("Borrower") promises  to  pay  to
UNITED  STATES NATIONAL BANK OF OREGON ("Lender"), or order, in lawful
money of the United States of America, on demand, the principal amount
of  One Million & 00/100 Dollars ($1,000,000.00) or so much as may  be
outstanding,   together  with  interest  on  the  unpaid   outstanding
principal balance of each advance.  Interest shall be calculated  from
the date of each advance until repayment of each advance.

PAYMENT.   Borrower  will  pay  this loan  immediately  upon  Lender's
demand.   In  addition, Borrower will pay regular monthly payments  of
all  accrued  unpaid interest due as of each payment  date,  beginning
September 30, 1996, with all subsequent interest payments to be due on
the last day of each month after that.  Interest on this Agreement  is
computed on a 365/360 simple interest basis; that is, by applying  the
ratio  of the annual interest rate over a year of 360 days, multiplied
by  the outstanding principal balance, multiplied by the actual number
of  days  the  principal balance is outstanding.   Borrower  will  pay
Lender  at  Lender's  address shown above or at such  other  place  as
Lender  may designate in writing.  Unless otherwise agreed or required
by  applicable  law, payments will be applied first to accrued  unpaid
interest,  then to principal, and any remaining amount to  any  unpaid
collection costs and late charges.

VARIABLE  INTEREST  RATE.   The interest rate  on  this  Agreement  is
subject to change from time to time based on changes in an index which
is the Lender's Prime Rate.  This is the rate of interest which Lender
from  time  to  time establishes as its Prime Rate  and  is  not,  for
example,  the lowest rate of interest which Lender collects  from  any
borrower or class of borrowers (the "Index').  The interest rate shall
be  adjusted  without notice effective on the day  Bank's  prime  rate
changes.   Lender  will  tell Borrower the  current  Index  rate  upon
Borrower's  request.  Borrower understands that Lender may make  loans
based on other rates as well.  The interest rate change will not occur
more  often  than each Day.  The Index currently is 8.250% per  annum.
The  interest  rate to be applied to the unpaid principal  balance  of
this  Agreement will be at a rate equal to the Index, resulting in  an
initial rate of 8.250% per annum.
<PAGE> 103
PREPAYMENT. Except for the foregoing, Borrower may pay without penalty
all  or  a  portion of the amount owed earlier than it is due.   Early
payments  will  not,  unless agreed to by Lender in  writing,  relieve
Borrower  of  Borrower's obligation to continue to  make  payments  of
accrued  unpaid  interest.   Rather, they will  reduce  the  principal
balance due.

DEFAULT.  Borrower will be in default if any of the following happens:
(a)  Borrower falls to make any payment when due. (b) Borrower  breaks
any  promise Borrower has made to Lender, or Borrower fails to  comply
with  or to perform when due any other term, obligation, covenant,  or
condition contained in this Agreement or any agreement related to this
Agreement, or in any other agreement or loan Borrower has with Lender.
(c)  Any  representation or statement made or furnished to  Lender  by
Borrower  or  on  Borrower's  behalf is false  or  misleading  in  any
material  respect  either now or at the time made  or  furnished.  (d)
Borrower  becomes insolvent, a receiver is appointed for any  part  of
Borrower's  property, Borrower makes an assignment for the benefit  of
creditors,  or  any  proceeding is commenced  either  by  Borrower  or
against  Borrower  under any bankruptcy or insolvency  laws.  (e)  Any
creditor  tries  to take any of Borrower's property  on  or  in  which
Lender  has  a lien or security interest.  This includes a garnishment
of  any of Borrower's accounts with Lender. (f) Any guarantor dies  or
any  of the other events described in this default section occurs with
respect  to  any  guarantor of this Agreement. (g) A material  adverse
change  in  Borrower's  financial condition, or  Lender  believes  the
prospect  of  payment or performance of the indebtedness is  impaired.
(h) Lender in good faith deems itself insecure.

If  any  default, other than a default in payment, is curable  and  if
Borrower has not been given a notice of a breach of the same provision
of  this Agreement within the preceding twelve (12) months, it may  be
cured  (and no event of default will have occurred) if Borrower, after
receiving  written notice from Lender demanding cure of such  default:
(a)  cures  the default within fifteen (15) days; or (b) if  the  cure
requires  more  than  fifteen (15) days, immediately  initiates  steps
which  Lender  deems in Lender's sole discretion to be  sufficient  to
cure the default and thereafter continues and completes all reasonable
and  necessary  steps  sufficient to produce  compliance  as  soon  as
reasonably practical.

LENDER'S  RIGHTS.  Upon default, Lender may declare the entire  unpaid
principal  balance on this Agreement and all accrued  unpaid  interest
immediately  due,  without notice, and then  Borrower  will  pay  that
amount.   Upon default, including failure to pay upon final  maturity,
Lender,  at  its option, may also, if permitted under applicable  law,
increase  the  variable  interest rate  on  this  Agreement  to  5.000
percentage  points over the Index.  The interest rate will not  exceed
the  maximum rate permitted by applicable law.  Lender may hire or pay
someone else to help collect this Agreement if Borrower does not  pay.
Borrower also will pay Lender that amount.  This includes, subject  to
any limits under applicable law, Lender's attorneys' fees and Lender's
legal expenses whether or not there is a lawsuit, including attorneys'
fees  and legal expenses for bankruptcy proceedings (including efforts
to  modify  or vacate any automatic stay or injunction), appeals,  and
any  anticipated post-judgment collection services.  If not prohibited
by applicable law, Borrower also will pay any court costs, in addition
to  all other sums provided by law.  This Agreement has been delivered
to  Lender and accepted by Lender in the State of Oregon.  If there is
a  lawsuit,  Borrower agrees upon Lender's request to  submit  to  the
jurisdiction of the courts of Multnomah County, the State  of  Oregon.
Subject  to  the  provisions on arbitration, this Agreement  shall  be
governed by and construed in accordance with the laws of the State  of
Oregon.

RIGHT  OF  SETOFF.  Borrower grants to Lender a contractual possessory
security  interest in, and hereby assigns, convoys, delivers, pledges,
and  transfers to Lender all Borrower's right, title and  interest  in
and to, Borrower's accounts with Lender (whether checking, savings, or
some  other  account), including without limitation all accounts  held
jointly  with someone else and all accounts Borrower may open  in  the
future,  excluding however all IRA and Keogh accounts, and  all  trust
accounts  for  which  the  grant  of  a  security  interest  would  be
prohibited  by  law.   Borrower  authorizes  Lender,  to  the   extent
permitted  by  applicable law, to charge or setoff all sums  owing  on
this Agreement against any and all such accounts.

LINE  OF CREDIT.  This Agreement evidences a revolving line of credit.
Advances under this Agreement, as well as directions for payment  from
Borrower's accounts, may be requested orally or in writing by Borrower
or  by  an authorized person.  Lender may, but need not, require  that
all  oral  requests be confirmed in writing.  Borrower  agrees  to  be
<PAGE> 104
liable  for  all  sums  either: (a) advanced in  accordance  with  the
instructions  of  an  authorized person or  (b)  credited  to  any  of
Borrower's  accounts with Lender, regardless of the fact that  persons
other  than those authorized to borrow have authority to draw  against
the accounts.  The unpaid principal balance owing on this Agreement at
any  time  may  be evidenced by endorsements on this Agreement  or  by
Lender's   internal  records,  including  daily  computer  print-outs.
Lender  will have no obligation to advance funds under this  Agreement
if:  (a)  Borrower or any guarantor is in default under the  terms  of
this  Agreement  or any agreement that Borrower or any  guarantor  has
with  Lender,  including  any agreement made in  connection  with  the
signing of this Agreement; (b) Borrower or any guarantor ceases  doing
business or is insolvent; (c) any guarantor seeks, claims or otherwise
attempts to limit, modify or revoke such guarantor's guarantee of this
Agreement  or  any  other loan with Lender; (d) Borrower  has  applied
funds  provided  pursuant to this Agreement for  purposes  other  than
those  authorized by Lender; or (e) Lender in good faith deems  itself
insecure  under  this Agreement or any other agreement between  Lender
and Borrower.

ARBITRATION.  Lender and Borrower agree that all disputes, claims  and
controversies  between them, whether individual, joint,  or  class  in
nature,  arising  from this Agreement or otherwise, including  without
limitation contract and tort disputes, shall be arbitrated pursuant to
the  Rules  of the American Arbitration Association, upon  request  of
either  party.   No act to take or dispose of any collateral  securing
this Agreement shall constitute a waiver of this arbitration agreement
or  be  prohibited  by  this  arbitration agreement.   This  includes,
without   limitation,  obtaining  injunctive  relief  or  a  temporary
restraining  order; foreclosing by notice and sale under any  deed  of
trust or mortgage; obtaining a writ of attachment or imposition  of  a
receiver;  or  exercising any rights relating  to  personal  property,
including  taking  or  disposing  of such  property  with  or  without
judicial process pursuant to Article 9 of the Uniform Commercial Code.
Any  disputes,  claims, or controversies concerning the lawfulness  or
reasonableness  of any act, or exercise of any right,  concerning  any
collateral  securing this Agreement, including any claim  to  rescind,
reform,  or  otherwise modify any agreement relating to the collateral
securing  this  Agreement, shall also be arbitrated, provided  however
that  no  arbitrator shall have the right or the power  to  enjoin  or
restrain  any act of any party.  Judgment upon any award  rendered  by
any  arbitrator  may  be  entered in any  court  having  jurisdiction.
Nothing  in  this  Agreement shall preclude  any  party  from  seeking
equitable relief from a court of competent jurisdiction.  The  statute
of  limitations, estoppel, waiver, laches, and similar doctrines which
would otherwise be applicable in an action brought by a party shall be
applicable in any arbitration proceeding, and the commencement  of  an
arbitration proceeding shall be deemed the commencement of  an  action
for  these purposes.  The Federal Arbitration Act shall apply  to  the
construction,  interpretation,  and enforcement  of  this  arbitration
provision.

CONTINUING  VALIDITY.  Except as expressly changed by this  Agreement,
the  terms  of  the original obligation or obligations, including  all
agreements  evidenced or securing the obligation(s), remain  unchanged
and  in  full  force and effect.  Consent by Lender to this  Agreement
does   not  waive  Lender's  right  to  strict  performance   of   the
obligation(s)  as  changed, nor obligate Lender  to  make  any  future
change  in  terms.   Nothing  in  this  Agreement  will  constitute  a
satisfaction of the obligation(s).  It is the intention of  Lender  to
retain  as  liable parties all makers and endorsers  of  the  original
obligation(s),  including accommodation parties.  Unless  a  party  is
expressly  released  by  Lender in writing.  Any  maker  or  endorser,
including accommodation makers, will not be released by virtue of this
Agreement.  If any person who signed the original obligation does  not
sign  this Agreement below, then all parties signing below acknowledge
that   this   Agreement   is  given  conditionally,   based   on   the
representation  to Lender that the non-signing party consents  to  the
changes  and  provisions of this Agreement or otherwise  will  not  be
released  by  it.   This  waiver  applies  not  only  to  any  initial
extension,  modification or release, but also to all  such  subsequent
actions.

LATE  CHARGE.  If a payment is 19 days or more past due, Borrower will
be charged a late charge of 5% of the delinquent payment.


PERIODIC  REVIEW.  Lender will review the loan periodically.   At  the
time  of  the review, Borrower will furnish Lender with any additional
information  regarding  Borrower's financial  condition  and  business
operations that Lender requests.  This information may include, but is
not limited to, financial statements, tax returns, lists of assets and
<PAGE> 105
liabilities, agings of receivables and payables, inventory  schedules,
budgets   and  forecasts.   If  upon  review,  Lender,  in  its   sole
discretion,  determines that there has been a material adverse  change
in  Borrower's financial condition, Borrower will be in default.  Upon
default, Lender shall have all rights specified herein.

DEMAND NOTE.  BORROWER ACKNOWLEDGES AND AGREES THAT (A) THIS NOTE IS A
DEMAND  NOTE,  AND  LENDER IS ENTITLED TO DEMAND BORROWER'S  IMMEDIATE
PAYMENT  IN FULL OF ALL AMOUNTS OWING HEREUNDER, (B) NEITHER  ANYTHING
TO  THE  CONTRARY  CONTAINED HEREIN OR IN  ANY  OTHER  LOAN  DOCUMENTS
(INCLUDING BUT NOT LIMITED TO, PROVISIONS RELATING TO DEFAULTS, RIGHTS
OF CURE, DEFAULT RATE OF INTEREST, INSTALLMENT PAYMENTS, LATE CHARGES,
PERIODIC REVIEW OF BORROWER'S FINANCIAL CONDITION, AND COVENANTS)  NOR
ANY  ACT  OF  LENDER PURSUANT TO ANY SUCH PROVISIONS  SHALL  LIMIT  OR
IMPAIR LENDER'S RIGHT OR ABILITY TO REQUIRE BORROWER'S PAYMENT IN FULL
OF  ALL AMOUNTS OWING HEREUNDER IMMEDIATELY UPON LENDER'S DEMAND,  AND
(C)  UPON  LENDER  MAKING  ANY  SUCH  DEMAND,  LENDER  SHALL  HAVE  NO
OBLIGATION  TO  MAKE ANY ADVANCE UNDER THIS NOTE  OR  UNDER  THE  LOAN
DOCUMENTS.

CREDIT  ACT  -  CHECKING ACCOUNT NUMBER 022-0016-224  LOCATED  AT  THE
ALBANY  COMMUNITY  BRANCH.  Borrower has requested  and  been  granted
Lender's  Commercial  Line of Credit Automatic Cash  Transfer  Service
("Credit ACT").  So long as this Note is in place, Borrower authorizes
Lender  to draw from Borrower's available line of credit and  transfer
funds   automatically  to  Borrower's  commercial   checking   account
described  in  the heading of this paragraph ("Checking  Account")  in
accordance with this section.  So long as this agreement is in  place,
Lender agrees to make an automatic cash transfer from Borrower's  line
of  credit  to its Checking Account in increments of $500.00,  to  pay
checks  that would otherwise overdraw Borrower's Checking  Account  by
$100.00 or more, up to Borrower's available credit limit.  The  amount
of each Credit ACT transfer will be an advance under the terms of this
Note.   There is no charge for using Credit ACT.  Borrower  agrees  to
pay  prevailing overdraft or other applicable checking account charges
then  in effect if an overdraft may not be paid because an ACT in  the
required  increment of $500.00 to pay the full amount of the overdraft
would exceed Borrower's credit limit.  If Borrower's credit limit  has
been  exceeded, and no other ACT privileges are available to Borrower,
any  check  presented for payment from Checking Account will,  at  the
sole  option  of  Lender,  either be paid, thus  overdrawing  Checking
Account, or dishonored.  Lender may change the terms of Credit ACT  at
any  time  by  giving Borrower written notice, sent to the  Borrower's
address  as shown in Lender's records, prior to the effective date  of
the change.

Lender  reserves  the  right to discontinue this service  upon  giving
written  notice  to  the  Borrower, at  Borrower's  address  shown  in
Lender's  records,  under  the  following  circumstances:  (1)  Lender
reasonably  believes  that  Borrower will be  unable  to  fulfill  its
repayment  obligations  because  of  a  material  adverse  change   in
Borrower's  financial circumstances. (2) Borrower  fails  to  promptly
provide  financial information that Lender has requested. (3) Borrower
is  in default of a material provision of any promissory Agreement  or
loan agreement with Lender.

If Lender discontinues further Credit ACT services due to any of these
circumstances,  Lender  will  mail  Borrower  written  notice  of  the
discontinuation and the reasons therefor.  After such notice is given,
Borrower  must  request in writing that its Credit ACT be  reinstated.
Before  Credit ACT privileges are reinstated, Lender may ask  Borrower
to  provide new information, at Borrower's expense.  If Borrower shows
Lender  that the circumstances that caused cancellation of Credit  ACT
services  have  ceased  to exist, Credit ACT  will  be  reinstated  at
Lender's sole option and discretion upon written notice to Borrower.

MISCELLANEOUS PROVISIONS.  This Agreement is payable on  demand.   The
inclusion of specific default provisions or rights of Lender shall not
preclude  Lender's right to declare payment of this Agreement  on  its
demand.   Lender  may delay or forgo enforcing any of  its  rights  or
remedies under this Agreement without losing them.  Borrower  and  any
other person who signs, guarantees or endorses this Agreement, to  the
extent  allowed by law, waive presentment, demand for payment, protest
and  notice  of  dishonor.   Upon any change  in  the  terms  of  this
Agreement, and unless otherwise expressly stated in writing, no  party
who  signs  this Agreement, whether as maker, guarantor, accommodation
maker or endorser, shall be released from liability.  All such parties
agree  that Lender may re-new or extend (repeatedly and for any length
<PAGE> 106
of  time)  this loan, or release any party or guarantor or collateral;
or  impair, fail to realize upon or perfect Lender's security interest
in  the  collateral;  and take any other action  deemed  necessary  by
Lender  without the consent of or notice to anyone.  All such  parties
also agree that Lender may modify this loan without the consent of  or
notice  to  anyone other than the party with whom the modification  is
made.

UNDER OREGON LAW, MOST AGREEMENTS, PROMISES AND COMMITMENTS MADE BY US
(LENDER)  AFTER  OCTOBER  3, 1989 CONCERNING LOANS  AND  OTHER  CREDIT
EXTENSIONS WHICH ARE NOT FOR PERSONAL, FAMILY OR HOUSEHOLD PURPOSES OR
SECURED SOLELY BY THE BORROWER'S RESIDENCE MUST BE IN WRITING, EXPRESS
CONSIDERATION AND BE SIGNED BY US TO BE ENFORCEABLE.

PRIOR TO SIGNING THIS AGREEMENT, BORROWER READ AND UNDERSTOOD ALL  THE
PROVISIONS  OF  THIS AGREEMENT, INCLUDING THE VARIABLE  INTEREST  RATE
PROVISIONS.   BORROWER  AGREES  TO THE  TERMS  OF  THE  AGREEMENT  AND
ACKNOWLEDGES RECEIPT OF A COMPLETED COPY OF THE AGREEMENT.

SYNTHETECH, INC.

X       \s\ M. Sreenivasan, President/CEO              X       \s\
Charles B. Williams, VP
     Authorized Officer                      Authorized Officer

LENDER:

United States National Bank of Oregon

By      \s\
     Authorized Officer




<PAGE> 107
                                                         Exhibit 10.14
                                                         of Form 10KSB
                                   
                           SYNTHETECH, INC.
                                   
              NONQUALIFIED STOCK OPTION LETTER AGREEMENT

TO:  Howard L. Farkas
     
     We are pleased to inform you that you have been selected by the
Plan Administrator of Synthetech, Inc.'s (the "Company") 1995
Incentive Compensation Plan, as amended and restated (the "Plan"), to
receive a nonqualified option for the purchase of 50,000 shares of the
Company's Common Stock at an exercise price of $1.81 per share.  A
copy of the Plan is attached and incorporated into this Agreement by
reference.
     
     The terms of the option are as set forth in the Plan and in this
Agreement.  The most important of the terms set forth in the Plan are
summarized as follows:
     
     Term:  The term of the option is ten years from date of grant,
unless sooner terminated.
     
     Exercise:  During your lifetime only you can exercise the option.
The Plan also provides for exercise of the option by the personal
representative of your estate, by the beneficiary you have designated
on forms prescribed by and filed with the Company (a "Designated
Beneficiary"), or the beneficiary of your estate following your death.
You may use the Notice of Exercise of Nonqualified Stock Option in the
form attached to this Agreement when you exercise the option.  Please
note that a different Notice of Exercise form will be required if, at
the time of exercise, the Company does not have an effective
registration statement for the shares to be issued pursuant to the
exercise.
     
     Payment for Shares:  The option may be exercised by the delivery
of:
     
     (a)  Cash, personal check (unless, at the time of exercise, the
Plan Administrator determines otherwise), bank certified or cashier's
check;
     
     (b)  Unless the Plan Administrator in its sole discretion
determines otherwise, shares of the capital stock of the Company held
by you for a period of at least six months (or any shorter period
necessary to avoid a charge to the Company's earnings for financial
reporting purposes) having a fair market value at the time of
exercise, as determined in good faith by the Plan Administrator, equal
to the exercise price.
     
     Withholding Taxes:  As a condition to the exercise of a
nonqualified stock option, you shall make such arrangements as the
Company may require for the satisfaction of any federal, state or
local withholding tax obligations that may arise in connection with
                                 1
<PAGE> 108
such exercise.  The Company shall have the right to retain without
notice sufficient shares of stock to satisfy the withholding
obligation.  To the extent permitted or required by the Company, you
may satisfy the withholding obligation by electing to have the Company
or related corporation withhold from the shares to be issued upon
exercise that number of shares having a fair market value equal to the
amount required to be withheld.  Individuals subject to Section 16 of
the Exchange Act must comply with certain requirements in order to
make such election.
     
     Termination:  Unless otherwise determined at any time by the Plan
Administrator, the option will terminate immediately upon termination
for cause, as defined in the Plan, or three years after termination of
service as a result of retirement, early retirement at the Company's
request, disability, or death or three months after all other
terminations, but in each case not later than the remaining term of
the option.
     
     Transfer of Option:  The option is not transferable except by
will, to a Designated Beneficiary, or by the applicable laws of
descent and distribution.
     
     Vesting:  The option shall vest and become exercisable according
to the following schedule:
                                                 
             Date On and After Which     Portion of Total
              Option is Exercisable       Option Which is
                                            Exercisable
                                                 
          Date of Grant                         0%
                                                 
          March 31, 1997                        33%
                                                 
          Each full month thereafter         2.77777%
                                                 
          March 31, 1999                       100%

In addition, the vesting of the option shall accelerate to 100% in the
event of your death during the time you are serving on the Board of
Directors.  If your position as a member of the Board of Directors of
the Company ceases for any reason, and unless by its terms the option
sooner terminates or expires, then you may exercise, for a five-year
period after such cessation, that portion of your option which is
exercisable at the time of cessation, but your option shall terminate
at the end of such five-year period following such cessation as to all
shares for which it has not theretofore been exercised.
     
     Holding Period:  If an individual subject to Section 16 of the
Exchange Act sells shares of Common Stock obtained upon the exercise
of a stock option within six months after the date the option was
granted, such sale may result in short-swing profit recovery under
Section 16(b) of the Exchange Act.
                                 2
<PAGE> 109
     Date of Grant:  The date of grant of the option is November 7,
1996.
     
     AT THE PRESENT TIME, THE COMPANY HAS AN EFFECTIVE REGISTRATION
STATEMENT WITH RESPECT TO THE SHARES THAT WILL BE ISSUED UPON THE
EXERCISE OF THIS OPTION.  THE COMPANY INTENDS TO MAINTAIN THIS
REGISTRATION BUT HAS NO OBLIGATION TO DO SO.  IN THE EVENT THAT SUCH
REGISTRATION IS NO LONGER EFFECTIVE, YOU WILL NOT BE ABLE TO EXERCISE
THE OPTION UNLESS EXEMPTIONS FROM REGISTRATION UNDER FEDERAL AND STATE
SECURITIES LAWS ARE AVAILABLE; SUCH EXEMPTIONS FROM REGISTRATION ARE
VERY LIMITED AND MIGHT BE UNAVAILABLE.
     
     Please execute the Acceptance and Acknowledgment set forth below
on the enclosed copy of this Agreement and return it to the
undersigned.
                              
                              Very truly yours,
                              
                              SYNTHETECH, INC.
                              
                              
                              
                              
                              By___________________________________
                              
                                Its __________________________________

                                       3

<PAGE> 110
                                                         Exhibit 10.15
                                                         of Form 10KSB
                                   
                           SYNTHETECH, INC.
                                   
              NONQUALIFIED STOCK OPTION LETTER AGREEMENT

TO:  Howard L. Farkas
     
     We are pleased to inform you that you have been selected by the
Plan Administrator of Synthetech, Inc.'s (the "Company") 1995
Incentive Compensation Plan, as amended and restated (the "Plan"), to
receive a nonqualified option for the purchase of 15,000 shares of the
Company's Common Stock at an exercise price of $7.50 per share.  A
copy of the Plan is attached and incorporated into this Agreement by
reference.
     
     The terms of the option are as set forth in the Plan and in this
Agreement.  The most important of the terms set forth in the Plan are
summarized as follows:
     
     Term:  The term of the option is ten years from date of grant,
unless sooner terminated.
     
     Exercise:  During your lifetime only you can exercise the option.
The Plan also provides for exercise of the option by the personal
representative of your estate, by the beneficiary you have designated
on forms prescribed by and filed with the Company (a "Designated
Beneficiary"), or the beneficiary of your estate following your death.
You may use the Notice of Exercise of Nonqualified Stock Option in the
form attached to this Agreement when you exercise the option.  Please
note that a different Notice of Exercise form will be required if, at
the time of exercise, the Company does not have an effective
registration statement for the shares to be issued pursuant to the
exercise.
     
     Payment for Shares:  The option may be exercised by the delivery
of:
     
     (a)  Cash, personal check (unless, at the time of exercise, the
Plan Administrator determines otherwise), bank certified or cashier's
check;
     
     (b)  Unless the Plan Administrator in its sole discretion
determines otherwise, shares of the capital stock of the Company held
by you for a period of at least six months (or any shorter period
necessary to avoid a charge to the Company's earnings for financial
reporting purposes) having a fair market value at the time of
exercise, as determined in good faith by the Plan Administrator, equal
to the exercise price.
     
     Withholding Taxes:  As a condition to the exercise of a
nonqualified stock option, you shall make such arrangements as the
Company may require for the satisfaction of any federal, state or
                                 1
<PAGE> 111
local withholding tax obligations that may arise in connection with
such exercise.  The Company shall have the right to retain without
notice sufficient shares of stock to satisfy the withholding
obligation.  To the extent permitted or required by the Company, you
may satisfy the withholding obligation by electing to have the Company
or related corporation withhold from the shares to be issued upon
exercise that number of shares having a fair market value equal to the
amount required to be withheld.  Individuals subject to Section 16 of
the Exchange Act must comply with certain requirements in order to
make such election.
     
     Termination:  Unless otherwise determined at any time by the Plan
Administrator, the option will terminate immediately upon termination
for cause, as defined in the Plan, or three years after termination of
service as a result of retirement, early retirement at the Company's
request, disability, or death or three months after all other
terminations, but in each case not later than the remaining term of
the option.
     
     Transfer of Option:  The option is not transferable except by
will, to a Designated Beneficiary, or by the applicable laws of
descent and distribution.
     
     Vesting:  The option shall vest and become exercisable according
to the following schedule:
                                                 
             Date On and After Which     Portion of Total
              Option is Exercisable       Option Which is
                                            Exercisable
                                                 
          Date of Grant                         0%
                                                 
          On the first Annual Meeting           20%
          of Shareholders after Date of
          Grant
                                                 
          On the second Annual Meeting          40%
          of Shareholders after Date of
          Grant
                                                 
          On the third Annual Meeting           60%
          of Shareholders after Date of
          Grant
                                                 
          On the fourth Annual Meeting          80%
          of Shareholders after Date of
          Grant
                                                 
          On the fifth Annual Meeting          100%
          of Shareholders after Date of
          Grant

In addition, if your position as a member of the Board of Directors of
the  Company ceases for any reason, and unless by its terms the option
                               2
<PAGE> 112
sooner  terminates or expires, then you may exercise, for a three-year
period  after  such cessation, that portion of your  option  which  is
exercisable at the time of cessation, but your option shall  terminate
at  the end of such three-year period following such cessation  as  to
all shares for which it has not theretofore been exercised.
     
     Holding Period:  If an individual subject to Section 16 of the
Exchange Act sells shares of Common Stock obtained upon the exercise
of a stock option within six months after the date the option was
granted, such sale may result in short-swing profit recovery under
Section 16(b) of the Exchange Act.
     
     Date of Grant:  The date of grant of the option is November 7,
1996.
     
     AT THE PRESENT TIME, THE COMPANY HAS AN EFFECTIVE REGISTRATION
STATEMENT WITH RESPECT TO THE SHARES THAT WILL BE ISSUED UPON THE
EXERCISE OF THIS OPTION.  THE COMPANY INTENDS TO MAINTAIN THIS
REGISTRATION BUT HAS NO OBLIGATION TO DO SO.  IN THE EVENT THAT SUCH
REGISTRATION IS NO LONGER EFFECTIVE, YOU WILL NOT BE ABLE TO EXERCISE
THE OPTION UNLESS EXEMPTIONS FROM REGISTRATION UNDER FEDERAL AND STATE
SECURITIES LAWS ARE AVAILABLE; SUCH EXEMPTIONS FROM REGISTRATION ARE
VERY LIMITED AND MIGHT BE UNAVAILABLE.
     
     Please execute the Acceptance and Acknowledgment set forth below
on the enclosed copy of this Agreement and return it to the
undersigned.
                              
                              Very truly yours,
                              
                              SYNTHETECH, INC.
                              
                              
                              
                              
                              By___________________________________
                              
                                Its _______________________________
                                  
                                   3

<PAGE> 113
                                                         Exhibit 10.16
                                                         of Form 10KSB
                                   
                           SYNTHETECH, INC.
                                   
              NONQUALIFIED STOCK OPTION LETTER AGREEMENT

TO:  Page E. Golsan III
     
     We are pleased to inform you that you have been selected by the
Plan Administrator of Synthetech, Inc.'s (the "Company") 1995
Incentive Compensation Plan, as amended and restated (the "Plan"), to
receive a nonqualified option for the purchase of 15,000 shares of the
Company's Common Stock at an exercise price of $7.50 per share.  A
copy of the Plan is attached and incorporated into this Agreement by
reference.
     
     The terms of the option are as set forth in the Plan and in this
Agreement.  The most important of the terms set forth in the Plan are
summarized as follows:
     
     Term:  The term of the option is ten years from date of grant,
unless sooner terminated.
     
     Exercise:  During your lifetime only you can exercise the option.
The Plan also provides for exercise of the option by the personal
representative of your estate, by the beneficiary you have designated
on forms prescribed by and filed with the Company (a "Designated
Beneficiary"), or the beneficiary of your estate following your death.
You may use the Notice of Exercise of Nonqualified Stock Option in the
form attached to this Agreement when you exercise the option.  Please
note that a different Notice of Exercise form will be required if, at
the time of exercise, the Company does not have an effective
registration statement for the shares to be issued pursuant to the
exercise.
     
     Payment for Shares:  The option may be exercised by the delivery
of:
     
     (a)  Cash, personal check (unless, at the time of exercise, the
Plan Administrator determines otherwise), bank certified or cashier's
check;
     
     (b)  Unless the Plan Administrator in its sole discretion
determines otherwise, shares of the capital stock of the Company held
by you for a period of at least six months (or any shorter period
necessary to avoid a charge to the Company's earnings for financial
reporting purposes) having a fair market value at the time of
exercise, as determined in good faith by the Plan Administrator, equal
to the exercise price.
     
     Withholding Taxes:  As a condition to the exercise of a
nonqualified stock option, you shall make such arrangements as the
Company may require for the satisfaction of any federal, state or
                              1
<PAGE> 114
local withholding tax obligations that may arise in connection with
such exercise.  The Company shall have the right to retain without
notice sufficient shares of stock to satisfy the withholding
obligation.  To the extent permitted or required by the Company, you
may satisfy the withholding obligation by electing to have the Company
or related corporation withhold from the shares to be issued upon
exercise that number of shares having a fair market value equal to the
amount required to be withheld.  Individuals subject to Section 16 of
the Exchange Act must comply with certain requirements in order to
make such election.
     
     Termination:  Unless otherwise determined at any time by the Plan
Administrator, the option will terminate immediately upon termination
for cause, as defined in the Plan, or three years after termination of
service as a result of retirement, early retirement at the Company's
request, disability, or death or three months after all other
terminations, but in each case not later than the remaining term of
the option.
     
     Transfer of Option:  The option is not transferable except by
will, to a Designated Beneficiary, or by the applicable laws of
descent and distribution.
     
     Vesting:  The option shall vest and become exercisable according
to the following schedule:
                                                 
             Date On and After Which     Portion of Total
              Option is Exercisable       Option Which is
                                            Exercisable
                                                 
          Date of Grant                         0%
                                                 
          On the first Annual Meeting           20%
          of Shareholders after Date of
          Grant
                                                 
          On the second Annual Meeting          40%
          of Shareholders after Date of
          Grant
                                                 
          On the third Annual Meeting           60%
          of Shareholders after Date of
          Grant
                                                 
          On the fourth Annual Meeting          80%
          of Shareholders after Date of
          Grant
                                                 
          On the fifth Annual Meeting          100%
          of Shareholders after Date of
          Grant

In addition, if your position as a member of the Board of Directors of
the Company ceases for any reason, and unless by its terms the option
sooner terminates or expires, then you may exercise, for a three-year
                               2
<PAGE> 115
period after such cessation, that portion of your option which is
exercisable at the time of cessation, but your option shall terminate
at the end of such three-year period following such cessation as to
all shares for which it has not theretofore been exercised.
     
     Holding Period:  If an individual subject to Section 16 of the
Exchange Act sells shares of Common Stock obtained upon the exercise
of a stock option within six months after the date the option was
granted, such sale may result in short-swing profit recovery under
Section 16(b) of the Exchange Act.
     
     Date of Grant:  The date of grant of the option is November 7,
1996.
     
     AT THE PRESENT TIME, THE COMPANY HAS AN EFFECTIVE REGISTRATION
STATEMENT WITH RESPECT TO THE SHARES THAT WILL BE ISSUED UPON THE
EXERCISE OF THIS OPTION.  THE COMPANY INTENDS TO MAINTAIN THIS
REGISTRATION BUT HAS NO OBLIGATION TO DO SO.  IN THE EVENT THAT SUCH
REGISTRATION IS NO LONGER EFFECTIVE, YOU WILL NOT BE ABLE TO EXERCISE
THE OPTION UNLESS EXEMPTIONS FROM REGISTRATION UNDER FEDERAL AND STATE
SECURITIES LAWS ARE AVAILABLE; SUCH EXEMPTIONS FROM REGISTRATION ARE
VERY LIMITED AND MIGHT BE UNAVAILABLE.
     
     Please execute the Acceptance and Acknowledgment set forth below
on the enclosed copy of this Agreement and return it to the
undersigned.
                              
                              Very truly yours,
                              
                              SYNTHETECH, INC.
                              
                              
                              
                              
                              By___________________________________
                              
                                Its __________________________________

                                     3

<PAGE> 116
                                                         Exhibit 10.17
                                                         of Form 10KSB
     
     SYNTHETECH, INC.                                    PURCHASE
                                                            ORDER
     1290 Industrial Way PO Box 646
     Albany, Oregon 97321
     Ph: 541-967-6575
     FAX: 541-967-9424
     
The following number must appear on all related
correspondence, shipping papers, and invoices:
P.O. NUMBER:  72412

To:                                     Ship To:
     R.L. Reimers Construction          Not Applicable
     3514 Conser Road, N.E.
     Albany, Oregon 97321
     Ph: 926-7766  FAX: 926-2908

 P.O. DATE    REQUISITIONER    SHIP VIA   F.O.B. POINT        TERMS
June 17, 1996   M.R. McVay       N.A.         N.A.        TO BE DEFINED


 QTY    UNIT                          DESCRIPTION               UNIT PRICE TOTAL

  1      1     Contractor shall provide the labor, equipment and $250000 $250000
               materials to perform sitework mobilization for the
               Synthetech Inc. new facility at 1290 Industrial Way.
               The purchase order will cover the initial phases of
               the project and work completed against P.O. 72412
               will apply to the overall contract to be negotiated by
               July 3, 1996.

                                                  SUBTOTAL     $250000

                                                 SALES TAX          $0.00

                                     SHIPPING AND HANDLING          $0.00

                                                     OTHER          $0.00

                                                     TOTAL     $250000

1.   Please send two copies of your invoice.

                                             \s\ Mitchell R. McVay
                                        X
                                             Authorized by
                                          Date:  June 17, 1996
          
<PAGE> 117                         
                         R.L. REIMERS COMPANY
                                   
                          GENERAL CONTRACTORS
                                   
                                   
May 21, 1996

Synthetech
Production Plant
1290 Industrial Way
Albany, OR  97321

Dear Mitch McVay,

The following is a list of R.L. Reimers Company rental and labor
rates:

Labor
     Ronald Reimers      $40.00 per hour
     Project Manager     $38.00 per hour
     Foreman             $36.00 per hour
     Carpenter           $32.00 per hour
     Laborer             $28.50 per hour

                   Day       Week             Month   Operated/hour
Laser Level      $ 25.00  $  100.00        $  250.00
Beam Saw         $ 25.00  $  100.00        $  250.00
Demo Saw         $ 35.00  $  100.00        $  300.00
Uniloader        $120.00  $  400.00        $  900.00
Job Trailer                                $  200.00
Generator 4-5 K  $ 40.00  $  135.00        $  500.00
Generator 6 KW   $ 50.00  $  150.00        $  550.00
580K Backhoe     $220.00  $  700.00        $2,000.00   $ 60.00
Dump Truck                                             $ 50.00
Dump Truck & Trailer                                   $ 60.00
Scissor Lift     $ 90.00  $  250.00        $  800.00
Gator Cart       $ 50.00  $  200.00        $  600.00
Compactor        $ 35.00  $  100.00        $  300.00
Trash Pump       $ 35.00  $  100.00        $  300.00
D5 Dozer         $350.00  $1,350.00        $4,100.00   $ 65.00
E120 Trackhoe    $400.00  $1,400.00        $4,300.00   $ 85.00

Materials and Subcontractors are cost plus 8%.

Terms Net 10 Days


/s/ Ron Reimers
<PAGE> 118
                                   
                         R.L. REIMERS COMPANY
                                   
                          GENERAL CONTRACTORS
                                   
                                   
Synthetech project control outline

I.   Budgets

II.  Billings
     A.   Monthly billings
     B.   Invoice copies
     C.   Discounts
     E.   Lien releases

III. Budget Variance analysis and cost to complete

IV.  Standard AGC Contract

<PAGE> 119
                                                         Exhibit 10.18
                                                         of Form 10KSB
     
     SYNTHETECH, INC.                                    PURCHASE
                                                            ORDER
     1290 Industrial Way PO Box 646
     Albany, Oregon 97321
     Ph: 541-967-6575
     FAX: 541-967-9424

The following number must appear on all related
correspondence, shipping papers, and invoices:
P.O. NUMBER:  72409 ADDENDUM

To:                                     Ship To:
     CE/Western                         NA
     1025 Bain SE
     Albany, Oregon
     97321

 P.O. DATE    REQUISITIONER    SHIP VIA   F.O.B. POINT        TERMS
  8/23/96          MRM            NA           NA


 QTY    UNIT                          DESCRIPTION   UNIT PRICE  TOTAL

               Contractor shall provide the engineering design for
               the chemical production facility, complete the city
               building permit requirements and complete the ODEQ construction
               permit requirements per the attached work scope.  The
               work includes Civil, Architectural, Structural, Mechanical,
               HVAC and Electrical.
  1                                                PRICE PER ATTACHED
QUOTATION            $240,000                                 $240,000

                                                  SUBTOTAL    $240,000

                                                 SALES TAX

                                     SHIPPING AND HANDLING

                                                     OTHER

                                                     TOTAL    $240,000

1.   Please send two copies of your invoice.

                                           \s\ Mitchell R. McVay
                                           8/23/96
                                        X
                                             Authorized by
Date
<PAGE> 120
                                   
             Proposal to Provide Professional Engineering
                                   
                 Services and Construction Management
                                   
                                   
                                   
                                   
                                   
                                   
                                   
                                   
                                   
                                   
                                   
                             Submitted to
                                   
                                   
                                   
                           SYNTHETECH, INC.
                                   
                                   
                                   
                            Albany, Oregon
                                   
                                   
                                   
                                   
                                   
                                   
                                   
                                   
                                   
                                   
                                   
                             Submitted by
                                   
                                   
                                   
                     CE/WESTERN ENGINEERING, INC.
                                   
                                   
                                   
                                   
                                   
                             May 24, 1996
                                   
<PAGE> 121                                   
                                   
                                   
Synthetech, Inc. Proposal
                                       Project No. 2091
                                                       
          
     SCOPE OF WORK
     
     Listed below is the Scope of Work from CE/Western
     Engineering for this project:
     
     TASK 1 - Structural and Value Engineering
           Perform a redesign of building based on H3 Occupancy Rating with
           input from contractor, owner and suppliers.
           Provide required structural drawings for permitting and field
           construction of building
     
     TASK 2 - On-Site Construction Coordination and Management
           Provide coordination of contractors, required inspections, and
           project status for owner.
     
     TASK 3 - Mechanical and Electrical Design
           Provide engineering services and coordination as requested by
           owner.

<PAGE> 122
                              Synthetech, Inc. Proposal
                                       Project No. 2091
                                                       
     
     FEE BASIS AND SCHEDULE
     
     We propose to furnish the described work on an
     engineering service and reimbursable expense basis.
     The estimated cost for our services follows:
     
               SCOPE TASK 1             $ 135,000
     
               SCOPE TASK 2             See attached rates
     
               SCOPE TASK 3             See attached rates
     
     In addition, all expenses related to this work will be
     invoiced at the actual cost incurred and will include,
     but not be limited to, automobile mileage, copies,
     telephone, living expenses, all travel costs and any
     other direct expenses (please see next page).
     
     Progressive Payments
     
     Project progressive billings are to be made at the end
     of each month.  Each monthly invoice will be based upon
     the services provided for that month, in accordance
     with the enclosed Billing Rate Schedule.  Payments are
     due within thirty days following the billing date.  All
     invoiced amounts not paid within forty-five (45) days
     of issue shall be subject to late charges at the rate
     of one and one-half percent (1.5%) per month.
     
     Project Duration and Schedule
     
     Upon receipt of an authorized approval signature, the
     work will be scheduled to begin as soon as possible and
     will be coordinated with the requirements of both
     parties.

<PAGE> 123                                                       
                              Synthetech, Inc. Proposal
                                       Project No. 2091
                                                       
            STANDARD BILLING RATE SCHEDULE (Revised May 01,
                                 1995)
     
     Labor:
     
          Principals
          
               Merel Jones                  $85/Hr
          
               Brian Downs                  $75/Hr
          
          Structural Engineer               $65/Hr
          
          Civil Engineer                    $65/Hr
          
          Mechanical Engineer               $60/Hr
          
          Environmental Specialist          $55/Hr
          
          Project Coordinator               $60/Hr
          
          Control Consultant                $45/Hr
          
          Electrical Engineer               $65/Hr
          
          CAD Drafter                   $25-$35/Hr
          
          CAD Designer                  $35-$45/Hr
          
          Computer Specialists              $65/Hr
          
          Accounting                        $35/Hr
          
          Administrative/Clerical           $25/Hr
          
          CAD/Computer Time               $8.50/Hr
     
     Expenses:
          
          Travel and Living Expenses       At Cost
          
          Phone, Fax, Postage, Fed Ex      At Cost
          
          Drawing Plots                  $4.00/ea.
          
          Blueprints                     $3.50/ea.
          
          Mileage                       $0.30/mile
          
          Photocopies                    $0.15/ea.
     
<PAGE> 124
                         Synthetech, Inc. Proposal
                                       Project No. 2091
     APPROVALS
     
     Scope Changes
     Any scope changes from this proposal will be
     reviewed and agreed to by both parties.
     Additional work entered into as a result of such
     changes will be authorized through the use of a
     written change order signed by the client's
     representative and by Merel Jones for CE/Western
     Engineering.  Any additional fees resulting from
     the change order will be itemized on monthly
     invoices.
     
     Engineer's Responsibilities
     CE/Western Engineering will be responsible for the
     professional quality and technical accuracy of all
     designs, drawings, specifications, and other
     services furnished by CE/Western Engineering under
     this agreement.  We shall, at our own cost,
     correct or revise any errors or deficiencies in
     the designs, drawings, and specifications.
     
     CE/Western Engineering warrants that its services
     are performed under the general direction of
     Registered Professional Engineers and with the
     usual thoroughness and competence of the
     engineering standards.  No other warranty or
     representation, either express or implied, is
     included or intended in its proposals, contract or
     repairs, either written or oral.
     
     Cancellation Clause
     In the event of cancellation of the project,
     CE/Western Engineering will be paid for work up to
     the time of cancellation any balance due.  Also,
     CE/Western Engineering will be paid a 15%
     cancellation fee on work not completed at the time
     of cancellation.
     
     Default
     In the event either party fails to perform its
     obligation under this agreement, the other parties
     shall have remedies provided by the law.
     
     Approvals
     This proposal must be signed and returned to
     CE/Western Engineering within forty-five (45) days
     to be valid.
     
     CE/WESTERN ENGINEERING, INC.
     
     
     /s/ Merel A. Jones by BUD               /s/ Scott
     A. Wright
     ____________________________
     ____________________________
     Merel A. Jones, P.E.                    Scott A.
     Wright
     President                     Project Coordinator
     
     SYNTHETECH, INC.
     
     
     /s/ Mitchell R. McVay
     ____________________________
     Authorized Representative

<PAGE> 125     
                                                    Exhibit 10.19
                                                         of Form 10KSB
     
     SYNTHETECH, INC.                                    PURCHASE
                                                            ORDER
     1290 Industrial Way PO Box 646
     Albany, Oregon 97321
     Ph: 541-967-6575
     FAX: 541-967-9424

The following number must appear on all related
correspondence, shipping papers, and invoices:
P.O. NUMBER:  72430

To:  R.L. Reimers Co.                   Ship To:
     3514 Conser Road, N.E.
     Albany, Oregon 97321

     Ph: 926-7766  FAX: 926-2908

 P.O. DATE    REQUISITIONER    SHIP VIA   F.O.B. POINT        TERMS
September 4, 1996  MRM            NA                       Net 10 Days


 QTY                                  DESCRIPTION   UNIT PRICE  TOTAL

          August, 1996 progression billing for plant expansion project
          work by R.L. Reimers Company.  Payment to be applied to
          total project cost.                                 $189,000





                                                  SUBTOTAL    $189,000

                                                 SALES TAX

                                     SHIPPING AND HANDLING

                                                     OTHER

                                                     TOTAL    $189,000
1.  Please send two copies of your invoice.
2.  Reference the P.O. number on the invoice.

                                             \s\ Mitchell R. McVay
                                        X
                                             Authorized by
                                             Date:  9/4/96

<PAGE> 126                                   
                         R.L. REIMERS COMPANY
                                   
                          GENERAL CONTRACTORS
                                   
                                   
Synthetech project control outline

I.   Budgets

II.  Billings
     A.   Monthly billings
     B.   Invoice copies
     C.   Discounts
     E.   Lien releases

III. Budget Variance analysis and cost to complete

IV.  Standard AGC Contract


<PAGE> 127
                                                         Exhibit 10.20
                                                         of Form 10KSB
     
     SYNTHETECH, INC.                                    PURCHASE
                                                            ORDER
     1290 Industrial Way PO Box 646
     Albany, Oregon 97321
     Ph: 541-967-6575
     FAX: 541-967-9424

The following number must appear on all related
correspondence, shipping papers, and invoices:
P.O. NUMBER:  72436

To:  R.L. Reimers Construction Co.      Ship To:
     3514 Conser Road, N.E.                  Synthetech Inc.
     Albany, Oregon 97321                    1290 Industrial Way
     926-7766                                Albany, Oregon

 P.O. DATE    REQUISITIONER    SHIP VIA   F.O.B. POINT        TERMS
November 7, 1996   MRM            NA           NA


 QTY                                  DESCRIPTION   UNIT PRICE  TOTAL

          Completion of Synthetech building per attached breakdown
          starting in the month of September 1996.          $1,730,200


          Utility Building Area-Includes waste berm, pumphouse (15ft
          by 30ft)
          glycol building (30ft by 45ft), cooling tower basin, spill
          containment
          berm, 25ft by 30ft slab and extension of existing waste
          storage.                                            $140,500

                                                  SUBTOTAL  $1,870,000

                                                 SALES TAX

                                     SHIPPING AND HANDLING

                                                     OTHER

                                                     TOTAL  $1,870,000
1.  Please send two copies of your invoice.
2.  Reference the P.O. number on the invoice.

                                             \s\ Mitchell R. McVay
                                        X
                                             Authorized by
                                             Date:  11/7/96

<PAGE> 128                                   
                         R.L. REIMERS COMPANY
                                   
                          GENERAL CONTRACTORS
                                   
                                   
Synthetech project control outline

I.   Budgets

II.  Billings
     A.   Monthly billings
     B.   Invoice copies
     C.   Discounts
     E.   Lien releases

III. Budget Variance analysis and cost to complete

IV.  Standard AGC Contract

<PAGE> 129 
                                                        Exhibit 10.21
                                                         of Form 10KSB
     
     SYNTHETECH, INC.                                    PURCHASE
                                                            ORDER
     1290 Industrial Way PO Box 646
     Albany, Oregon 97321
     Ph: 541-967-6575
     FAX: 541-967-9424

The following number must appear on all related
correspondence, shipping papers, and invoices:
P.O. NUMBER:  72459

To:  Olsson Industrial Electric         Ship To:
     P.O. Box 70413                          Synthetech Inc.
     Eugene, Oregon 97401                    1290 Industrial Way
     1919 Laura- Springfield                 Albany, Oregon
     Phone: 541-747-8460
     FAX: 541-747-4846

 P.O. DATE    REQUISITIONER    SHIP VIA   F.O.B. POINT        TERMS
February 20, 1997  MRM


 QTY                                  DESCRIPTION   UNIT PRICE  TOTAL
          Contractor shall install the plant electrical system as
          specified by the Synthetech Electrical Bid Specifications 
          dated 1/30/97, Bid Meeting Minutes issued 1/31/97 and 
          Specification and Clarification Memorandum issued 2/7/97.
          LUMP SUM BID PER OLLSON INDUSTRIAL ELECTRIC 2/11/97$333,040
          Addendum 2/20/97:  600 Amp Service-- Two 3" rigid conduit w/
          four 350 MCM cable & one #1 wire per conduit to existing service.
                                                                $2,824

                                                  SUBTOTAL    $335,864

                                                 SALES TAX

                                     SHIPPING AND HANDLING

                                                     OTHER

                                                     TOTAL    $335,864
1.  Please send two copies of your invoice.
2.  Reference the P.O. number on the invoice.

                                             \s\ Mitchell R. McVay
                                        X
                                             Authorized by
                                             Date:  2/20/97


<PAGE> 130
                                                         Exhibit 10.22
                                                         of Form 10KSB
     
     SYNTHETECH, INC.                                    PURCHASE
                                                            ORDER
     1290 Industrial Way PO Box 646
     Albany, Oregon 97321
     Ph: 541-967-6575
     FAX: 541-967-9424

The following number must appear on all related
correspondence, shipping papers, and invoices:
P.O. NUMBER:  42472

To:  Oregon Industrial Contractors, Inc.       Ship To:
Synthetech, Inc.
     P.O. Box B                                1290 Industrial Way
     Albany, Oregon 97321                      Albany, Oregon
     Ph: 541-928-2901                          Ph: 541-967-6575
     Fax: 541-928-7759

 P.O. DATE    REQUISITIONER    SHIP VIA   F.O.B. POINT        TERMS
May 7, 1997        MRM            NA           NA         See Quotation


 QTY                                  DESCRIPTION   UNIT PRICE  TOTAL

          Contractor shall provide the labor, tools, equipment and
          material specified for the piping, equipment installation and work
          platforms as specified by drawings and written specifications 
          supplied by Synthetech.Price per Oregon Industrial Contractors, 
          Inc. Quotation Dated
          April 30, 1997      T&M NOT TO EXCEED               $626,276

                                                  SUBTOTAL    $626,276

                                                 SALES TAX

                                     SHIPPING AND HANDLING

                                                     OTHER

                                                     TOTAL    $626,276
1.  Please send two copies of your invoice.
2.  Reference the P.O. number on the invoice.

                                             \s\ Mitchell R. McVay
                                        X
                                             Authorized by
                                             Date:  May 2, 1997

<PAGE> 131   
                                                         Exhibit 23
                                                         to Form 10KSB
                                   
                                   
                                   
               CONSENT OF INDEPENDENT PUBLIC ACCOUNTANTS
                                   
                                   
As independent public accountants, we hereby consent to the
incorporation of our report dated May 16, 1997 included in this Form
10-KSB for the year ended March 31, 1997, into Synthetech, Inc.'s
previously filed Registration Statement Nos. 33-45913, 33-64621 and
333-8203.


Arthur Andersen LLP
Portland, Oregon,
  June 18, 1997


<TABLE> <S> <C>

<PAGE>
<ARTICLE> 5
<LEGEND>
This schedule contains summary financial information extracted from
the March 31, 1997 10KSB Balance Sheets, Income Statements, and Cash
Flow Statements, and is qualified in its entirety by reference to such
financial statements.
</LEGEND>
       
<S>                                  <C>
<PERIOD-TYPE>                         12-MOS
<FISCAL-YEAR-END>                     MAR-31-1997
<PERIOD-END>                          Mar-31-1997
<CASH>                                6740000
<SECURITIES>                           176000
<RECEIVABLES>                          695000
<ALLOWANCES>                                0
<INVENTORY>                           1887000
<CURRENT-ASSETS>                     10520000
<PP&E>                                6339000
<DEPRECIATION>                              0
<TOTAL-ASSETS>                       17323000
<CURRENT-LIABILITIES>                 1278000
<BONDS>                                     0
<COMMON>                                14000
                       0
                                 0
<OTHER-SE>                           15797000
<TOTAL-LIABILITY-AND-EQUITY>        173230000
<SALES>                              12797000
<TOTAL-REVENUES>                     12797000
<CGS>                                 5103000
<TOTAL-COSTS>                         6549000
<OTHER-EXPENSES>                            0
<LOSS-PROVISION>                            0
<INTEREST-EXPENSE>                       1000
<INCOME-PRETAX>                       6632000
<INCOME-TAX>                          2520000
<INCOME-CONTINUING>                   4112000
<DISCONTINUED>                              0
<EXTRAORDINARY>                             0
<CHANGES>                                   0
<NET-INCOME>                          4112000
<EPS-PRIMARY>                             .29
<EPS-DILUTED>                             .29
        

</TABLE>


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