NEORX CORP
DEF 14A, 1997-04-14
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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<PAGE>
================================================================================
                            SECURITIES AND EXCHANGE COMMISSION
                                  WASHINGTON, D.C. 20549
                            -----------------------------------

                                SCHEDULE 14A INFORMATION

Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934
                               (Amendment No.   )
             Filed by the Registrant (X)
             Filed by a Party other than the Registrant ( )

Check the appropriate box:
                 ( ) Preliminary Proxy Statement
                 ( ) Confidential, for Use of the Commission Only 
                     (as permitted by Rule 14a-6(e)(2))
                 (X) Definitive Proxy Statement
                 ( ) Definitive Additional Materials
                 ( ) Soliciting Material Pursuant to Section 240.14a-11(c) or 
                     Section 240.14a-12

                                   NEORX CORPORATION
       ------------------------------------------------------------------------
                   (Name of Registrant as Specified in Its Charter)

       ------------------------------------------------------------------------
       (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):

 ( ) $125 per Exchange Act Rules 0-11(c)(1)(ii), 14a-6(i)(1), 14a-6(i)(2) or
     Investment Company Act Rule 20a-1(c)
 ( ) $500 per each party to the controversy pursuant to Exchange Act Rule
     14a-6(i)(3)
 ( ) Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11

CALCULATION OF FILING FEE
Title of each class of securities to which transaction applies:
Aggregate number of securities to which transaction applies:
Per unit price or other underlying value of transaction computed pursuant to
Exchange Act Rule 0-11:
Proposed maximum aggregate value of transaction:
Total Fee Paid

 ( ) Fee paid previously with preliminary materials.
 ( ) Check box if any part of the fee is offset as provided by Exchange Act Rule
     0-11(a)(2) and identify the filing for which the offsetting fee was paid
     previously.  Identify the previous filing by registration statement number,
     or the Form or Schedule and the date of its filing.

Amount Previously Paid:_______________________  Filing Party:   ________________
Form, Schedule or
Registration Statement No.:___________________  Date Filed:_____________________

================================================================================

<PAGE>

                                NEORX CORPORATION

                  Notice of 1997 Annual Meeting of Shareholders

TO THE SHAREHOLDERS:

        The 1997 Annual Meeting of Shareholders  (the "Annual Meeting") of NeoRx
Corporation  (the  "Company") will be held at The  Mountaineers  Club, 300 Third
Avenue West, Seattle, Washington 98119, on Tuesday, May 13, 1997, at 9 a.m., for
the following purposes:

        1.     To elect six members to the Company's Board of Directors;

        2.     To  ratify  the  appointment  of  KPMG Peat  Marwick LLP  as the
               Company's  independent public accountants for 1997;

        3.     To consider  and  approve an  increase in the  number of shares 
               issuable  under the  Company's  Restated  1994 Stock  Option Plan
               from  2,500,000  shares to  4,000,000 shares; and

        4.     To transact  such other  business as may properly  come  before
               the Annual Meeting and any adjournments or postponements thereof.

        Your  attention  is directed to the  accompanying  Proxy  Statement  for
further  information  with respect to the matters to be acted upon at the Annual
Meeting.  To  constitute  a quorum  for the  conduct of  business  at the Annual
Meeting, it is necessary that holders of a majority of all outstanding shares of
the Company's  Common Stock be present in person or be represented by proxy.  To
ensure representation at the Annual Meeting, you are urged to complete, sign and
date  the   enclosed   proxy  card  and  return  it  promptly  in  the  enclosed
postage-prepaid envelope.

        The record date for determining  shareholders entitled to notice of, and
to vote at, the Annual Meeting is the close of business on March 28, 1997.

                                BY ORDER OF THE BOARD OF DIRECTORS



                                /s/ Richard L. Anderson
                                ----------------------------------
                                RICHARD L. ANDERSON
                                Senior Vice President, Chief Financial Officer,
                                Secretary and Treasurer

April 8, 1997
Seattle, Washington

        YOUR VOTE IS IMPORTANT.  ACCORDINGLY,  YOU ARE ASKED TO COMPLETE,  SIGN,
DATE AND RETURN THE  ACCOMPANYING  PROXY CARD  REGARDLESS OF WHETHER YOU PLAN TO
ATTEND THE ANNUAL MEETING.


<PAGE>
                                 PROXY STATEMENT

General

        This Proxy Statement is furnished in connection with the solicitation by
the Board of Directors (the "Board of Directors") of NeoRx Corporation  ("NeoRx"
or the  "Company")  of  proxies in the  accompanying  form for use at the Annual
Meeting  of  Shareholders  to  be  held  on  Tuesday,  May  13,  1997,  and  any
adjournments or postponements thereof (the "Annual Meeting"). The Annual Meeting
will be held at 9 a.m. at The Mountaineers Club, 300 Third Avenue West, Seattle,
Washington 98119.

        The Company's  principal  office is located at 410 West Harrison Street,
Seattle,  Washington 98119. The approximate date of mailing this Proxy Statement
and the enclosed proxy card is April 12, 1997.

Voting Securities

        Only shares of the Company's Common Stock, $.02 par value per share (the
"Common  Stock"),  outstanding  at the close of business on March 28, 1997,  the
record date for determining shareholders,  are entitled to receive notice of and
to vote at the Annual  Meeting (the "Record  Date").  At the Record Date,  there
were 16,515,141 shares of Common Stock outstanding. The presence in person or by
proxy of holders of record of a majority of the shares of Common Stock  entitled
to vote is required to  constitute a quorum for the  transaction  of business at
the Annual  Meeting.  Each holder of Common Stock is  generally  entitled to one
vote per share held on the Record Date on each item to be voted on at the Annual
Meeting. In voting for the election of Directors,  however, each shareholder has
the right to  cumulate  his or her votes and cast as many  votes as are equal to
the  number  of  Directors  to be  elected  multiplied  by the  number  of  such
shareholder's  shares.  These votes may be cast for one candidate or distributed
among as many candidates as the shareholder  desires. If a shareholder wishes to
cumulate  his or her votes,  he or she should  multiply his or her shares by the
number of Directors to be elected  (deriving a cumulative  total) and then write
the number of votes for each Director next to each  Director's name on the proxy
card. The total votes cast in this manner may not exceed the  cumulative  total.
If a shareholder does not wish to cumulate votes for Directors, he or she should
indicate the vote for or against each nominee, as provided on the proxy card. On
all other proposals,  each share of Common Stock entitles its holder to one vote
on each proposal to be acted upon at the Annual Meeting.

        Under Washington law and the Company's  Articles of Incorporation,  if a
quorum is present at the Annual  Meeting:  (a) the six  nominees for election as
Directors  who receive  the  greatest  number of votes cast for the  election of
Directors by the shares  present in person or represented by proxy at the Annual
Meeting and entitled to vote will be elected  directors;  and (b) Proposal 2 and
Proposal  3  listed  in the  accompanying  Notice  of  1997  Annual  Meeting  of
Shareholders  will be  approved  if the  number  of  votes  cast in favor of the
proposal  exceeds the number cast against it. In the election of Directors,  any

<PAGE>

action other than a vote for a nominee will have the practical  effect of voting
against the nominee.  Abstention from voting will have no effect on the approval
of  Proposal 2 and  Proposal 3 since they will not  represent  votes cast at the
Annual Meeting for the purposes of approval of such proposals.  Brokers who hold
shares for the account of their clients may vote their  clients'  proxies in the
brokers' own  discretion as to the election of Directors and Proposal 2, but not
Proposal 3, if the clients have not furnished  voting  instructions  by ten days
prior to the Annual  Meeting.  Broker nonvotes will have no effect on Proposal 3
since they are not considered shares entitled to vote on these matters.

        The proxy cards also confer  discretionary  authority to vote the shares
authorized to be voted thereby on any proposal that was not known on the date of
this Proxy  Statement  but may  properly be  presented  for action at the Annual
Meeting.

     YOUR VOTE IS IMPORTANT.  ACCORDINGLY, YOU ARE ASKED TO COMPLETE, SIGN, DATE
AND RETURN THE ACCOMPANYING  PROXY CARD REGARDLESS OF WHETHER OR NOT YOU PLAN TO
ATTEND THE ANNUAL MEETING.


Revocation

        Any shareholder returning a proxy has the power to revoke it at any time
before shares  represented  thereby are voted at the Annual Meeting.  Any shares
represented by an unrevoked proxy will be voted unless the  shareholder  attends
the Annual Meeting and votes in person. A shareholder's  right to revoke a proxy
is not limited by or subject to compliance  with a specified  formal  procedure,
but written notice of such revocation should be given to the Company's Corporate
Secretary at or before the Annual Meeting.

Expenses of Solicitation

        The  Company  will  bear the  expense  of  printing  and  mailing  proxy
material.  In addition to the solicitation of proxies by mail,  solicitation may
be made by certain  Directors,  officers  and other  employees of the Company in
person  or  by  telephone,  facsimile  transmission,   telegraph  or  telex.  No
additional compensation will be paid for such solicitation.

        Arrangements   also  will  be  made  with  brokerage   firms  and  other
custodians,  nominees and fiduciaries to forward proxy solicitation  material to
certain  beneficial  owners of the Company's  Common Stock, and the Company will
reimburse  such  brokerage  firms,  custodians,  nominees  and  fiduciaries  for
reasonable out-of-pocket expenses incurred by them in connection therewith.


                                       2

<PAGE>



          SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

        The following table sets forth certain information  regarding beneficial
ownership, as of February 28, 1997, of the Common Stock by (a) each person known
by the Board of Directors to  beneficially  own more than 5% of the  outstanding
Common  Stock,  (b) each  Director  and  nominee for  Director,  (c) each of the
executive  officers  included in the  Summary  Compensation  Table,  and (d) all
executive officers and Directors as a group. Except as otherwise indicated,  the
Company believes that the beneficial owners of the shares listed below have sole
investment and voting power with respect to the shares.
<TABLE>
<CAPTION>

                                                            Shares         Percentage
                                                         Beneficially       of Common
        NAME                                                Owned             Stock
- ----------------------------------------------------     ------------      -----------

<S>                                                        <C>                  <C>  
Fund Asset Management, L.P.(1).......................      1,825,600            11.1%
    d/b/a Fund Asset Management
    800 Scudders Mill Road
    Plainsboro, New Jersey  08536

Ardsley Advisory Partners(2).........................      1,696,250            10.2%
    646 Steamboat Road
    Greenwich, Connecticut  06830

Boehringer Ingelheim International GmbH(3)...........      1,370,534             8.0%
    D6507 Ingelheim am Rhein
    Germany

Paul G. Abrams(4)....................................        440,922             2.6%

James G. Andress(5)..................................         15,000             *

Becky J. Bottino(6)..................................         49,630             *

Jack L. Bowman(7)....................................         19,000             *

Fred B. Craves(8)....................................        137,500             *

Lawrence H.N. Kinet(5)...............................         12,500             *

Carl-Heinz Pommer(9).................................         12,500             *

John M. Reno(10).....................................        136,512             *

Robert W. Schroff(11)................................        132,336             *

Bruce H. Walters(12).................................         96,675             *

Robert M. Littauer(13)...............................         14,040             *

Jeffrey J. Miller(13)................................             --             *

All executive officers and Directors as a group
 (13 persons) (14)...................................      1,066,615             6.1%
- ------------------
 *    Less than 1%.

                                       3

<PAGE>

<FN>
(1)   Fund Asset  Management,  L.P.  d/b/a Fund Asset  Management  ("FAM") is an
      indirectly   wholly  owned   subsidiary  of  Merrill  Lynch  &  Co.,  Inc.
      ("ML&Co.").  The securities  positions of FAM reported on Schedule 13G are
      also  reported on behalf of ML&Co.,  which may be deemed to share with FAM
      investment discretion and voting authority with respect to such positions.
      Information  for the Common  Stock owned by FAM is based on  Schedule  13G
      filed in February 1997, with the Securities and Exchange Commission.
(2)   Includes  156,250 shares  issuable upon exercise of warrants.  Information
      for the  Common  Stock  owned by  Ardsley  Advisory  Partners  is based on
      Schedule  13G filed in February  1997,  with the  Securities  and Exchange
      Commission.
(3)   Includes 625,000 shares issuable upon exercise of warrants.
(4)   Includes 306,750 shares subject to options exercisable within 60 days.
(5)   Includes 10,000 shares subject to options exercisable within 60 days.
(6)   Includes 47,625 shares subject to options exercisable within 60 days.
(7)   Includes 17,500 shares subject to options exercisable within 60 days.
(8)   Represents shares subject to options exercisable within 60 days.
(9)   Represents  shares  subject to options  exercisable  within 60 days. Does 
      not include 1,370,534 shares  beneficially owned  by Boehringer Ingelheim 
      International GmbH for  which  Mr.  Pommer  serves  as  representative on
      the  Board of Directors; Mr. Pommer disclaims beneficial ownership of such
      shares.
(10)  Includes 117,625 shares subject to options exercisable within 60 days.
(11)  Includes 112,625 shares subject to options exercisable within 60 days.
(12)  Includes 88,000 shares subject to options exercisable within 60 days.
(13)  Former  executive  officer;  resigned  from the  Company  September  27, 
      1996.  All options expired December 26, 1996.
(14)  Includes 860,125 shares subject to options exercisable within 60 days.
</FN>
</TABLE>

                        ELECTION OF DIRECTORS (PROPOSAL 1)

Nominees for Director

        Pursuant to the Company's  Articles of Incorporation,  six Directors are
to be  elected  by the  holders of Common  Stock at the  Annual  Meeting.  These
Directors  will serve one-year terms that will expire at the 1998 Annual Meeting
of  Shareholders  and until their  successors  have been elected and  qualified.
Unless a shareholder withholds his or her vote, each proxy will be voted for the
election of the following Directors:

        PAUL G. ABRAMS,  M.D.,  age 49, is a  co-founder  of the Company and has
been a Director  since January  1985.  He has been the  Company's  President and
Chief Executive  Officer since May 1990 and was Vice President,  Medical Affairs
from January 1985 to April 1990. From 1981 to 1984, Dr. Abrams held the position
of Expert in the Biological  Response  Modifiers  Program of the National Cancer
Institute.  Dr.  Abrams  holds  J.D.,  M.D.  and  B.A.  (Summa  Cum  Laude  with
Exceptional  Distinction) degrees from Yale University.  He is a board-certified
internist and medical oncologist and is an Affiliate  Associate Professor in the
Department of Radiology at the  University of  Washington.  Dr. Abrams serves on
the Board of  Directors  of the  Biotechnology  Industry  Organization  and is a
member of its Emerging Companies Section Board.

                                       4

<PAGE>

        JAMES G. ANDRESS,  age 58, has been a Director  since  November 1990. In
November 1996, Mr. Andress became Chief  Executive  Officer of  Warner-Chilcott,
PLC, a privately-held  pharmaceutical company. From 1989, he was President and a
director and, from June 1990, Chief Executive  Officer and, from June 1993, Vice
Chairman of Information  Resources,  Inc., a marketing  research and information
services company,  until October 1995, and remains a director at this time. From
1988 to 1989,  he was Chairman of  Pharmaceuticals  at the Beecham  Group PLC in
London,  a  pharmaceutical  company  that,  due to a merger,  has  since  become
SmithKline  Beecham.  From 1984 to 1988,  Mr.  Andress was  President  and Chief
Operating Officer of Sterling Drug Inc., a pharmaceutical  company.  Mr. Andress
is  a  director  of  Sepracor  Inc.,  The  Liposome  Company,   Inc.,  and  Xoma
Corporation,  all of which are  biotechnology  companies.  Mr. Andress is also a
director  of  Source   Informatics,   Inc.,  an  information   service  company,
Optioncare, Inc., a provider of home healthcare services, and Allstate Insurance
Corporation. Mr. Andress holds an M.B.A. degree from the Wharton Graduate School
of Business and a B.S.  degree from the United  States  Military  Academy,  West
Point.  Mr.  Andress  serves  on the  Compensation  Committee  of the  Board  of
Directors.

        JACK L. BOWMAN,  age 64, has been a Director  since January  1994.  From
1987 to December  1993,  before his  retirement,  Mr.  Bowman was Company  Group
Chairman of Johnson & Johnson Company, a multinational  pharmaceutical  company.
From 1983 to 1987, Mr. Bowman was Executive Vice President of American  Cyanamid
Corporation  and,  from  1981 to 1983,  President  of its  Lederle  Laboratories
Division.  Mr. Bowman is a director of Cell Therapeutics,  Inc., CytRx, Inc. and
Cellegy  Pharmaceuticals,  each of which is a biotechnology  company, and on the
Business  Advisory  Board of The Craves Group, a merchant bank. He holds a B.Ed.
degree from Western Washington University. Mr. Bowman serves on the Compensation
Committee of the Board of Directors.

        FRED B. CRAVES,  Ph.D.,  age 51, has been the Company's  Chairman of the
Board of Directors  since July 1993.  In January 1997,  Dr.  Craves  founded The
Craves Group,  a merchant bank focused on life  sciences.  In January 1994,  Dr.
Craves  co-founded  Burrill & Craves,  a merchant  bank  focused  on  healthcare
companies,  of which he was  President  and Chairman of the Board.  From January
1991 to April  1993,  he was Chief  Executive  Officer and  President  of Berlex
Biosciences, a research, development and manufacturing organization and a wholly
owned subsidiary of Schering AG, a multinational  pharmaceutical company. Berlex
Biosciences  was  created by merging  Codon,  a  biotechnology  company  that he
co-founded and served as Chairman of the Board and Chief Financial  Officer from
1982 to 1990, and the pharmaceutical business of Triton Biosciences. In 1981, he
co-founded  Creative  Biomolecules,  Inc., a  biotechnology  company  focused on
morphogenic  proteins.  Dr.  Craves is  Chairman  of the Board and Acting  Chief
Executive  Officer  of  Epoch  Pharmaceuticals,  and  is a  director  of  Incyte
Pharmaceuticals,  Inc., both biotechnology  companies.  Dr. Craves holds a Ph.D.
degree in  Pharmacology  and  Experimental  Toxicology  from the  University  of
California San Francisco  Medical Center,  an M.S.  degree in Pharmacology  from
Wayne State University and a B.S. degree in Biology from Georgetown  University.
Dr. Craves serves on the Audit Committee of the Board of Directors.

                                       5

<PAGE>

        LAWRENCE H.N. KINET,  age 49, has been a Director since October 1990. In
January  1995,  Mr. Kinet was  appointed  Chairman of the Board of Directors and
Chief Executive Officer of AKSYS, Ltd., a biomedical development company engaged
in the field of artificial kidney dialysis.  From January 1991 to December 1994,
he served as Chairman of the Board of Directors and Chief  Executive  Officer of
Oculon Corporation, a pharmaceutical development company engaged in the field of
anti-cataract  drugs.  From  1989 to  1992,  he was a  Managing  Partner  of The
Kensington Group, a management consulting partnership. From 1985 to 1988, he was
President and Corporate Group Vice President of Baxter World Trade  Corporation,
the  international  division of Baxter  International,  Inc.  Mr. Kinet holds an
M.B.A.  degree  from the  University  of  Chicago  and a B.Sc.  degree  from the
University  of  Birmingham,   England.   Mr.  Kinet  serves  on  the  Audit  and
Compensation Committees of the Board of Directors.

        CARL-HEINZ  POMMER,  age 50,  has been a  Director  since May 1994.  Mr.
Pommer has held various positions with Boehringer Ingelheim  International GmbH,
a European  pharmaceutical  company and shareholder of the Company,  since 1967,
most recently as Head of International Hospital Business since August 1993. From
April 1991 to July 1993, he was Manager,  International  Product Marketing,  and
from 1987 to 1991, Group Head,  International Product Marketing.  Mr. Pommer was
designated  as a nominee  for  election as a Director  by  Boehringer  Ingelheim
International GmbH pursuant to an agreement with the Company. Mr. Pommer holds a
degree  (Diplom-Kaufmann) from the University of Gottingen (Germany) in Business
Administration, Marketing and Sales. Mr. Pommer serves on the Audit Committee of
the Board of Directors.

        It is intended  that votes will be cast  pursuant to the enclosed  proxy
card for the election as  Directors of the  foregoing  nominees.  Executing  the
proxy  card  will  give the  proxies  the  authority  to vote the  shares in the
election of Directors as the proxies shall  determine.  If any nominee shall not
be a candidate for election as a Director at the Annual Meeting,  it is intended
that votes  will be cast  pursuant  to the  enclosed  proxy for such  substitute
nominee as may be nominated  by the existing  Directors.  No  circumstances  are
presently known that would render any nominee named above unavailable.

        Pursuant to the Company's Bylaws, shareholders seeking to nominate other
candidates  for election to the Board of  Directors  at the Annual  Meeting must
give written  notice to the Company's  Corporate  Secretary no less than 60 days
nor more than 90 days  before the  Annual  Meeting.  Such  notice  must  contain
certain  information as to the  shareholder  giving the notice and each proposed
nominee,  including information similar to that required under the federal proxy
rules.  If less than 70 days' notice or prior public  disclosure  of the date of
the scheduled  Annual Meeting is given,  notice by the shareholder must be given
not later than the tenth day  following  the earlier of the mailing of notice of
the Annual  Meeting and the date  public  disclosure  of the Annual  Meeting was
made. The Company's Bylaws provide that no person shall be elected a Director of
the Company unless  nominated in accordance  with the Bylaws.  As of the date of
this Proxy Statement,  the Company has not received any Director  nominations by
shareholders.

                                       6

<PAGE>


        The Board of Directors  met 12 times during the year ended  December 31,
1996. Each of the present Directors, except Messrs. Andress and Pommer, attended
at least 75% of the total number of meetings  held by the Board of Directors and
by all committees of the Board of Directors on which they served.

Committees of the Board

     The  Board  of  Directors  has two  committees:  an Audit  Committee  and a
Compensation Committee. It does not have a nominating committee.

        The Audit Committee currently consists of three non-employee  Directors:
Messrs.  Kinet and  Pommer,  and Dr.  Craves.  The Audit  Committee  reviews the
preparation  and audit of the Company's  accounts,  considers the  engagement of
independent  public  accountants  for the  ensuing  year  and the  terms of such
engagement,  reviews the scope of the audit  proposed by such  accountants,  and
receives and reviews the audit reports.  The Audit Committee met one time during
the year ended December 31, 1996.

        The  Compensation  Committee  currently  consists of three  non-employee
Directors:  Messrs.  Andress,  Bowman  and  Kinet.  The  Compensation  Committee
recommends  to the Board of Directors the salary and certain terms of employment
of the Company's  officers and  administers  the  Company's  Restated 1994 Stock
Option Plan and the grants of options thereunder. The Compensation Committee met
four times during the year ended December 31, 1996.

Compensation of Directors

        Directors of the Company receive no cash compensation for their services
to the Company in such  capacity.  Non-employee  Directors  receive stock option
grants under the  Company's  1991 Stock Option Plan for  Non-Employee  Directors
(the  "Directors  Plan").  Each new  non-employee  Director,  upon  election  or
appointment  to the Board of Directors,  receives an initial  option to purchase
10,000  shares of Common  Stock at an  exercise  price  equal to the fair market
value per share of Common Stock on the grant date.  Each  non-employee  Director
automatically receives an annual option grant to purchase 5,000 shares of Common
Stock  following each annual meeting of  shareholders at an exercise price equal
to the fair market value per share of Common  Stock on the grant date,  provided
that a Director  who has received an initial  grant for 10,000  shares of Common
Stock within five months prior to any such annual meeting of  shareholders  does
not  receive  the  annual  grant for such  annual  meeting.  Options  granted to
non-employee  Directors  upon  their  initial  appointment  or  election  become
exercisable in two equal  installments  beginning with the first  anniversary of
the grant date. The options  granted as of each annual  meeting of  shareholders
(including the Annual Meeting) become  exercisable in two equal  installments on
the  dates  of the next two  succeeding  annual  meetings  of  shareholders.  In
addition to options  granted  under the  Directors  Plan,  Dr.  Craves  receives
compensation under a consulting  agreement with the Company and received a stock
option  grant  under  the  Restated   1994  Stock  Option  Plan.   See  "Certain
Relationships and Related Transactions."

                                       7
<PAGE>


                              EXECUTIVE COMPENSATION

Compensation Summary

        The following table sets forth all cash compensation paid in each of the
last three years to the Company's Chief Executive Officer,  the four most highly
compensated  officers  in 1996  who  are  currently  in  office  and two  former
executive officers (the "named executive officers").
<TABLE>

                                SUMMARY COMPENSATION TABLE 
<CAPTION>

                                                               Long-Term Compensation
                                      Annual Compensation              Awards
                                 ---------------------------  ------------------------  
                                                               Restricted   Securities    All Other
                                                                 Stock      Underlying   Compensation
Name and Principal Position      Year   Salary($)   Bonus($)  Awards($)(1)  Options(#)      ($)(2)
- ---------------------------      ----   ---------   --------  ------------  ----------   -------------

<S>                               <C>    <C>        <C>                         <C>        <C>    
Paul G. Abrams                    1996   $258,457   $  1,700         --         125,000    $   696
President and Chief               1995    234,149         --         --              --        696
Executive Officer                 1994    223,660         --         --         450,000        696
  
Becky J. Bottino                  1996    107,237      1,700         --          25,000        388
Director, Manufacturing           1995    103,455         --         --          32,501        369
and Product Development           1994     94,092      7,770         --          65,750        321

John M. Reno                      1996    169,718      1,700         --          25,000      1,152
Vice President, Research          1995    163,746         --         --              --        680
and Development                   1994    156,013      7,770         --         125,000        640
  
Robert W. Schroff
Vice President and General        1996    157,925      1,700         --          25,000        336
Manager, Cardiovascular           1995    152,498         --         --              --        321
Products                          1994    144,522         --         --         115,000        341

Bruce H. Walters                  1996    137,551      1,700         --          25,000        908
Vice President, Human             1995    135,917      1,389         --              --        894
Resources                         1994    131,014         --         --          60,000        851

Robert M. Littauer
Senior Vice President,            1996    173,774     18,158         --          45,000        551
Chief Financial Officer           1995    194,752     13,896         --              --        696
and Treasurer (3)                 1994    185,731      7,210         --         130,000        696

Jeffrey J. Miller
Senior Vice President,            1996    178,203       1,700        --          45,000       551
Business Development and          1995    201,297       3,545        --              --       696
Legal Affairs,                    1994    191,737      29,552   $51,000         130,000       696
and Secretary (3)  
- -----------------------
<FN>

(1)   Dr.  Miller was awarded  8,000 shares of Common Stock under the  Company's
      1991 Restricted Stock Plan on October 13, 1994. The price of the Company's
      stock  on  the  date  of  grant  was  $6.38  per  share.  Restrictions  on
      transferability of the shares awarded terminated on January 5, 1995.

(2)   Consists of premiums paid under group term life insurance policies.

(3)   Mr. Littauer and Dr. Miller resigned from the Company September 27, 1996.
</FN>
</TABLE>

                                       8

<PAGE>



Stock Options

        The following table provides details  regarding stock options granted to
the named executive officers in 1996. In addition, in accordance with Securities
and  Exchange  Commission  ("SEC")  rules,  the  hypothetical  gains or  "option
spreads" that would exist for the respective  options are shown. These gains are
based on assumed rates of annual  compounded stock price  appreciation of 5% and
10% from the date the options were granted over their 10-year term.
<TABLE>

                                  OPTIONS GRANTED IN 1996
<CAPTION>
                                                                             Potential Realizable Value
                                                                             At Assumed Annual Rates of
                                                                              Stock Price Appreciation
                              Individual Grants                                   for Option Term 
- --------------------------------------------------------------------------  ---------------------------
                      Number of     Percent of    
                     Securities    All Options
                     Underlying     Granted to    Exercise 
                       Options     Employees in     Price      Expiration
Name                Granted(#)(1)     1996       Per Share($)    Date          5%$)(2)       10%($)(2)
- ------------------  -------------  ------------  ------------  -----------  ------------   ------------
<S>                    <C>             <C>           <C>        <C>             <C>         <C>      
Paul G. Abrams         125,000         12.9%         $7.00      5/13/2006       $550,283    1,394,525
                                                      
Becky J. Bottino        25,000          2.6           7.00      5/13/2006        110,057      278,905

John M. Reno            25,000          2.6           7.00      5/13/2006        110,057      278,905
   
Robert W. Schroff       25,000          2.6           7.00      5/13/2006        110,057      278,905
 
Bruce H. Walters        25,000          2.6           7.00      5/13/2006        110,057      278,905

Robert M. Littauer(3)   45,000          4.6           7.00      5/13/2006             --           --
  
Jeffrey J. Miller (3)   45,000          4.6           7.00      5/13/2006             --           --
- ------------------
<FN>
(1)   The options granted are performance-based  options that become exercisable
      on the ninth anniversary of the date of grant and expire 10 years from the
      date of  grant.  Exercisability  may be  accelerated  by the  Compensation
      Committee of the Board of Directors based on the Committee's assessment of
      the corporate performance against goals established annually.  All options
      were granted with an exercise  price equal to the fair market value of the
      Common Stock on the date of grant based on the closing price of the Common
      Stock as  quoted on the  Nasdaq  National  Market.  The  options  are also
      subject to accelerated  vesting upon the occurrence of certain events. See
      "Employment Agreements, Termination of Employment and Change of Control."

(2)   These amounts  result from the assumed  rates of stock price  appreciation
      required by the SEC and are not  intended to forecast  actual  stock price
      appreciation. Optionholders will experience no gain unless the stock price
      increases  during the option  term.  Such an  increase  would  benefit all
      shareholders.

(3)   Mr. Littauer and Dr. Miller resigned from the Company  September 27, 1996.
      These options were not exercisable and expired December 26, 1996.
</FN>
</TABLE>


                                       9

<PAGE>



Option Exercises in 1996 and Year-End Value Table

        The following  table sets forth  information on option  exercises in the
year ended  December 31, 1996 by the named  executive  officers and the value of
such officers' unexercised options at the end of 1996.
<TABLE>

                            AGGREGATED OPTION EXERCISES IN 1996
                                AND YEAR-END OPTION VALUES
<CAPTION>

                                                           Number of Securites
                                                         Underlying Unexercised      Value of Unexercised In- The
                                                              Options At                   Money Options at       
                              Shares                      December 31, 1996 (#)        December 31, 1996($)(1)
                           Acquired on       Value      --------------------------   ----------------------------
      Name                   Exercise     Realized($)   Exercisable  Unexercisable   Exercisable    Unexercisable
- --------------------       -----------    -----------   -----------  -------------   ------------   -------------
<S>                          <C>          <C>             <C>            <C>           <C>            <C>     
Paul G. Abrams                   --             --        306,750        383,750       $364,826       $307,136

Becky J. Bottino                 --             --         47,625         75,626         43,918         28,192

John M. Reno                  5,000       $ 26,250        112,938        100,812         58,015         78,490

Robert W. Schroff             8,800         46,200        107,938         95,812         58,015         78,490

Bruce H. Walters             10,000         81,250         88,000         59,500         76,206         40,952

Robert M. Littuaer(2)        80,042        154,543             --             --             --             --

Jeffrey J. Miller(2)         82,750        183,035             --             --             --             --
- --------------
<FN>

(1)   The value of unexercised  in-the-money  options is calculated based on the
      market  price per share on  December  31, 1996 of $4.13 as reported by the
      Nasdaq National  Market,  less the exercise  price.  There is no assurance
      that if and when these options are exercised that the  optionholders  will
      receive this value.

(2)   Mr. Littauer and Dr. Miller resigned from the Company  September 26, 1996
      The options were exercised before their expiration on December 26, 1996.
</FN>
</TABLE>

Report of the Compensation Committee on Executive Compensation

Statement of Compensation Philosophy

        The Company's executive  compensation  program primarily consists of two
parts: cash compensation and stock options.  The Company's overall philosophy is
to hire individuals who possess the requisite professional skills and managerial
track  records   demonstrated  from  successful   experiences  in  positions  of
comparable  scope  and  responsibility  in  healthcare  and other  research  and
industrial  settings,  who will help achieve the Company's mission of developing
targeted  biopharmaceuticals  to treat cancer and cardiovascular  diseases.  The
Company is committed to recruiting,  motivating and retaining senior  executives
with demonstrated talent and managerial leadership skills.


                                       10

<PAGE>



        The Company's  goal for total  compensation  is to be  competitive  with
other  biotechnology  enterprises.  The program places  significant  emphasis on
equity  participation  by granting  stock options to conserve cash and align the
interests of senior management with those of the Company's shareholders.

        Compensation  payments  in  excess  of $1  million  to each of the named
executive  officers are subject to a limitation on deductibility for the Company
under Section 162(m) of the Internal  Revenue Code of 1986, as amended.  Certain
performance-based   compensation   is  not   subject   to  the   limitation   on
deductibility.  Cash  compensation to the Chief  Executive  Officer or any other
executive  officer has never exceeded $1 million and the Compensation  Committee
does not expect cash  compensation in 1997 to the Chief Executive Officer or any
other  executive  officer to be in excess of $1 million.  The Board of Directors
intends to qualify option awards for the  performance-based  exception to the $1
million limitation on deductibility of compensation payments.

Cash-Based Compensation

        The Company's philosophy is to maintain executive cash compensation at a
competitive  level  that  is  sufficient  to  recruit  and  retain   individuals
possessing  the  above-mentioned  skills.  Determinations  of  appropriate  cash
compensation  levels are  generally  made  through  regular  participation  in a
variety of  industry  and  industry-related  surveys,  as well as by  monitoring
developments in key industries such as biotechnology  and  pharmaceuticals.  The
Company's cash  compensation  levels are designed to be  approximately  equal to
cash  compensation  paid by other  biotechnology  enterprises.  The survey  data
considered by the  Compensation  Committee in determining  1996 executive  total
cash  compensation  includes salary  information  provided by 111  biotechnology
enterprises  having between 51 and 149 employees (the  "Comparison  Group"),  of
which 75 are publicly  traded  companies.  Approximately  65% of these  publicly
traded companies are included in the Nasdaq  Pharmaceutical Stock Index referred
to in the Stock Price  Performance  Graph that  appears  elsewhere in this Proxy
Statement.  During 1996, Dr. Abrams  received a $40,000  adjustment in salary to
align his base  compensation  more closely with  industry.  With that, his total
cash compensation in 1996 was $260,157,  which placed him in the 30th percentile
of total  compensation paid to chief executive officers in the Comparison Group.
Dr.  Schroff  received  a  salary  adjustment  of  $13,755  to  align  his  base
compensation  more  closely  with  that of the  industry.  There  were no  other
increases to  executive  officers.  Total cash  compensation  for the  Company's
executive officers was in the 25th to 80th percentile of total compensation paid
to  executives  performing  similar  functions  in  companies  included  in  the
Comparison Group.

        Bonus  awards to  individuals  are  discretionary  and are  intended  to
recognize  outstanding  contributions  to the  Company.  In  1996,  the  Company
instituted a bonus award  program to reward  management up to 20% of base salary
in cash and/or Common Stock upon the accomplishment of certain goals approved by
the Board of Directors.  These goals included Food and Drug  Administration (the
"FDA") marketing  clearance,  forming  strategic  alliances,  achieving  product

                                       11
<PAGE>

milestones, increasing cash reserves and improving corporate valuation. Although
some of  these  goals  were  achieved  in whole  or in  part,  the  Compensation
Committee  determined  that no bonuses were to be paid from this plan.  In 1996,
all employees, including executive officers, received bonuses of $1,700 upon FDA
marketing clearance of the Company's first product,  VERLUMA(TM) Small Cell Lung
Cancer Imaging Kit.

Equity-Based Compensation

        Stock  options are viewed as a basic  element of the total  compensation
program and emphasize  long-term Company performance as measured by the creation
of shareholder value. Options under the Company's existing stock option plan are
granted  to  all  employees.   In  determining  the  size  of  the  grants,  the
Compensation Committee considers the amount and value of options currently held,
but focuses primarily on the executive's past and likely continued  contribution
to the Company, as well as the executive's relative position within the Company.
Although the  Compensation  Committee does not have a target ownership level for
Common  Stock  holdings  by  executives  and  key  employees,  the  Compensation
Committee's  objectives  are to enable such  persons to develop  and  maintain a
significant long-term ownership position in the Common Stock.

        Stock  options to executive  officers  have been granted at 100% of fair
market value on the date of grant. The Company has generally  awarded options to
executives  at the  time  of  employment  and  promotion,  and at  discretionary
intervals.  The Compensation  Committee seeks to keep its executive stock option
compensation  competitive  with  other  biotechnology  companies.  Stock  option
exercisability  is  determined by the  Compensation  Committee.  Options  become
exercisable  in periods  generally  ranging from one to nine years after date of
grant. In certain cases,  exercisability may be accelerated based on achievement
of corporate and individual objectives.

        The  stock   options   granted  to   executive   officers  in  1996  are
performance-based  options that become  exercisable  in the ninth year after the
date of grant and have a term of 10 years;  such option  grants were  granted to
all  employees  of the  Company  in  1996,  including  executive  officers.  The
Compensation  Committee may  accelerate  exercisability  of the options  granted
based upon  achievement  of corporate  goals  approved  annually by the Board of
Directors.  There  was no  acceleration  of the 1996  performance-based  grants.
During  the  year,  the  Compensation  Committee  accelerated  to all  employees
including  executive  officers  13% of the 1994  performance  based  grants upon
approval of VERLUMA.

        Submitted by the Compensation Committee of the Board of Directors


        James G. Andress
        Jack L. Bowman
        Lawrence H.N. Kinet

                                       12

<PAGE>


Stock Price Performance Graph

        The graph below compares the cumulative total shareholder  return on the
Company's  Common  Stock with the  cumulative  total  shareholder  return of the
Nasdaq Stock Market Index (US) and the Nasdaq  Pharmaceutical  Stocks Index,  an
index of  approximately  217  companies,  the  stocks of which are quoted on the
Nasdaq National Market, and the Primary Standard Industrial  Classification Code
Number (SIC) of which is #283 - Pharmaceutical Companies.

        Note: Stock price performance shown below for the Company is historical,
and not necessarily indicative of future price performance.
<TABLE>


               COMPARISON OF FIVE-YEAR CUMULATIVE TOTAL RETURN AMONG NEORX
                      CORPORATION, NASDAQ STOCK MARKET INDEX (US) AND
                          NASDAQ PHARMACEUTICAL STOCKS INDEX(1)
<CAPTION>
                           
                                           9/30/91  9/30/92  12/31/92  12/31/93  12/31/94  12/31/95  12/31/96
                                           -------  -------  --------  --------  --------  --------  --------
<S>                                         <C>      <C>       <C>       <C>       <C>       <C>       <C> 
NeoRx Corporation                           $100     $ 87      $130      $ 80      $ 42      $ 55      $ 36
Nasdaq Stock Market Index (US)               100      112       130       150       146       207       255
Nasdaq Pharmaceutical Stocks Index           100       85       103        92        69       127       127
<FN>

        (1) Assumes  $100  invested on September  30, 1991 in NeoRx  Corporation
Common Stock,  the Nasdaq Stock Market Index (US) and the Nasdaq  Pharmaceutical
Stocks Index.  Total return  performance  for the Nasdaq Stock Market Index (US)
and the  Nasdaq  Pharmaceutical  Stocks  Index is  weighted  based on the market
capitalization  of the firms  included in each index and assumes that  dividends
are reinvested. The Nasdaq Stock Market Index (US) and the Nasdaq Pharmaceutical
Stocks Index are produced and published by the Center for Research in Securities
Pricing at the University of Chicago.
</FN>
</TABLE>

Employment and Change of Control Agreements and Severance Agreements

        Each of the  executive  officers of the Company  has an  agreement  that
defines terms of employment  and change of control of the Company (as defined in
the   agreement).   A  change  of  control  occurs  through   certain   mergers,
consolidations, acquisitions of property or stock, liquidations, reorganizations
or sales of substantially all the assets of the Company.  The executive officers
may  receive 12 months  salary and a  proportioned  bonus if earned.  Also,  the
vesting of all options  outstanding  under the Company's  1984 Stock Option Plan
and Restated 1994 Stock Option Plan will be accelerated  and optionees will have
the right to exercise  all or a part of such  options  immediately  prior to any

                                       13
<PAGE>

such transaction.  Any unexercised  options will terminate,  except that, in the
event of a merger in which the shareholders of the Company receive capital stock
of  another  corporation,  such  unexercised  options  must  be  assumed  or  an
equivalent  option  substituted  by  the  successor  corporation.  A  qualifying
termination  under this agreement also is considered to occur when the executive
officers'  responsibilities  or authority are materially  reduced on more than a
short-term basis.  These agreements  automatically  renew  bi-annually  absent a
notice of nonrenewal by either party.

        The Company also has severance  agreements  with each executive  officer
that provides that the executive  officer would receive up to 12 months'  salary
if such  executive  officer is  terminated  "without  cause" (as  defined in the
agreement). The severance agreements allow the Company to reduce payments to the
former executive officers who undertake consulting or employment elsewhere.  The
agreement defines severance without cause to include a material reduction in the
executive officer's responsibility or authority.  These agreements automatically
renew bi-annually absent a notice of nonrenewal by either party.

Certain Relationships and Related Transactions

        On July 7, 1993, Dr. Fred B. Craves, the Company's Chairman of the Board
of Directors, entered into a consulting agreement with the Company that provides
that Dr.  Craves shall be retained as a general  advisor and  consultant  to the
Company's  management on all matters  pertaining to the Company's  business.  In
exchange for such services,  Dr. Craves is compensated $30,000 for each calendar
quarter of services, plus reasonable travel and other expenses. On July 7, 1993,
the  Company  also  granted  Dr.  Craves an option to  purchase a total of up to
125,000 shares of Common Stock over four years.  In 1996, the Board  accelerated
vesting of Dr.  Craves'  remaining  40,000  shares of the  option  grant for his
assistance in NeoRx's 1996 financing. On February 21, 1997, the Board granted to
Dr. Craves an option to purchase  60,000 of the Company's  Common Stock from the
Restated 1994 Stock Option Plan for continued  consulting  services.  The option
was granted at the then  current  market  price of the Common  Stock and becomes
exercisable  in two  equal  installments  beginning  one year  after the date of
grant. If Dr. Craves is terminated "without cause" (as defined in the consulting
agreement),  he is  entitled  to a pro rata  portion  of the  quarterly  fee for
services up to the date of  termination,  all expenses  incurred up to such date
and a payment equal to three months of service.

        In April 1996, the Company loaned Dr. Abrams $55,000,  bearing  interest
     at the applicable federal rate. The balance of loans due from Dr. Abrams to
the Company was $131,000 at December 31, 1996 and is due on demand.  Dr.  Abrams
is repaying the loans in monthly payments.

Compliance With Section 16(a) of the Securities Exchange Act of 1934

        Section  16(a)  of the  Securities  Exchange  Act of 1934,  as  amended,
requires the Company's  Directors and  executive  officers,  and persons who own

                                       14
<PAGE>

more than 10% of a registered  class of the Company's  securities,  to file with
the SEC the initial  reports of ownership and reports of changes in ownership of
Common Stock and other equity  securities of the Company.  Directors,  executive
officers and  greater-than-10%  shareholders  are required by SEC  regulation to
furnish the Company with copies of all Section 16(a) forms they file.

        To the  Company's  knowledge,  based solely on a review of the copies of
such  reports  furnished  to the Company and written  representations,  no other
reports were required  during the year ended  December 31, 1996, and all Section
16(a) filing  requirements  applicable to its Directors,  executive officers and
greater-than-10% shareholders were complied with in 1996.

Relationship with Auditor

        On  April  4,  1997,   the  Company's   Board  of   Directors,   at  the
recommendation  of its Audit  Committee,  terminated  the  engagement  of Arthur
Andersen LLP and selected KPMG Peat Marwick LLP as the Company's auditor.

        The  report  of  Arthur  Andersen  LLP  on the  Corporation's  Financial
statements  for either of the last two years did not contain an adverse  opinion
or a disclaimer of opinion and was not qualified or modified as to  uncertainty,
audit scope, or accounting principles.  During the Corporation's two most recent
years and subsequent  interim  periods  preceding the date of termination of the
engagement of Arthur  Andersen LLP, the  Corporation  was not in disagreement on
any  matter  of  accounting   principles  or  practices,   financial   statement
disclosure, or auditing scope or procedure, which disagreement,  if not resolved
to the  satisfaction  of Arthur  Andersen LLP, would have caused Arthur Andersen
LLP to make  reference to the subject matter of the  disagreement  in connection
with its report.

        The  Corporation had not consulted with KPMG Peat Marwick LLP during its
two most recent  years nor during any  subsequent  interim  period  prior to its
engagement  regarding the  application  of accounting  principles to a specified
transaction,  either  completed or proposed,  or the type of audit  opinion that
might be rendered on the Corporation's financial statements.

           RATIFICATION OF APPOINTMENT OF INDEPENDENT ACCOUNTANTS (PROPOSAL 2)

        Shareholders are asked to ratify the selection of KPMG Peat Marwick LLP,
independent  public  accountants,  as the  Company's  auditor  for 1997.  Unless
instructed  otherwise,   it  is  the  intention  of  the  person  named  in  the
accompanying  proxy to vote the shares  represented by properly executed proxies
for  ratification  of the  appointment  of KPMG Peat Marwick LLP as  independent
accountants.  Representatives  from KPMG Peat  Marwick  LLP are  expected  to be
present  at the  Annual  Meeting  to make a  statement  if they so desire and to
respond to appropriate questions.

        THE  BOARD  OF  DIRECTORS  RECOMMENDS  A VOTE  FOR RATIFICATION  OF THE 
APPOINTMENT OF KPMG PEAT MARWICK LLP.

                                       15
<PAGE>



            PROPOSAL TO INCREASE THE NUMBER OF SHARES ISSUABLE UNDER
                  THE COMPANY'S RESTATED 1994 STOCK OPTION PLAN
                                  (PROPOSAL 3)

        In 1994,  the  shareholders  approved  the 1994  Stock  Option  Plan (as
restated,  the "1994 Plan") and  authorized the Company to issue up to 2,500,000
shares of Common Stock.  As of February 28, 1997,  approximately  102,397 shares
remained  available for issuance under the 1994 Plan. The  shareholders  will be
requested  at the Annual  Meeting to approve an amendment to the 1994 Plan which
increases  by  1,500,000  the number of shares that may be issued under the 1994
Plan. The 1994 Plan is to promote Company success by aligning employee financial
interests with  long-term  shareholder  value.  The Board believes the number of
shares  remaining  available  for issuance will be  insufficient  to achieve the
purpose of the 1994 Plan over the term of such plan unless the additional shares
are  authorized.  The text of the 1994 Plan as amended  subject  to  shareholder
approval  is attached as Exhibit A to this Proxy  Statement.  Unless  instructed
otherwise,  it is the intention of the person named in the accompanying proxy to
vote the shares  represented by properly executed proxies to increase the number
of shares  issuable  under the Company's  Restated  1994 Stock Option Plan.  The
following summary of the 1994 Plan as amended subject to shareholder approval is
qualified  by  reference  to such  text  for a more  complete  statement  of its
provisions.

        The purpose of the 1994 Plan is to promote the  interests of the Company
and its  shareholders  by  strengthening  the  Company's  ability to attract and
retain  the  services  of  selected  employees,   officers,  directors,  agents,
consultants, advisors and independent contractors and to provide added incentive
to them by encouraging  stock ownership in the Company.  The Company's policy is
to grant stock options to all permanent, full-time employees to help ensure that
the shareholders'  long-term  interests and goals are closely aligned with those
of the  individuals  responsible  for the  Company's  day-to-day  operation  and
management.  The Company's  policy is to grant all employees  stock options upon
commencement of employment. The number of shares exercisable under each grant to
new  employees  is  based  on  the  employee's  level  of   responsibility   and
compensation.  Approximately 90 individuals are expected to receive grants under
the 1994 Plan.

        Stock Subject to the 1994 Plan.  The 1994 Plan provides for the grant of
options to acquire up to a total of 4,000,000 shares of Common Stock to selected
employees,  officers,  directors, agents, consultants,  advisors and independent
contractors of the Company, subject to certain restrictions, including an annual
maximum of 500,000  shares per  individual.  As of March 31,  1997,  the closing
price per share of Common Stock on the Nasdaq National Market was $4.94.

        Terms and Conditions of Stock Option Grants.  The 1994 Plan is currently
administered by the Compensation  Committee of the Board of Directors (the "Plan
Administrator").  At the discretion of the Plan  Administrator,  options granted
under  the 1994  Plan may be  either  nonqualified  stock  options  ("NSOs")  or
incentive  stock  options   ("ISOs"),   which  are  intended  to  meet  all  the
requirements  of an  "Incentive  Stock  Option" as defined in Section 422 of the
Internal Revenue Code of 1986, as amended (the "Code"). Under the 1994 Plan, the
Plan  Administrator may grant ISOs to any officer or employee of the Company and

                                       16
<PAGE>

may grant NSOs to any employee, officer, director, agent, consultant, advisor or
independent  contractor of the Company. All option grants, with the exception of
grants to greater than 10% shareholders as noted below, expire 10 years from the
date of grant unless otherwise established by the Plan Administrator. Generally,
option  grants vest and become  exercisable  in  increments at a rate of 25% per
year over a four-year period from grant date, unless otherwise determined by the
Plan  Administrator.  All ISOs and NSOs are granted such that the exercise price
is not less than 100% of the fair market  value of the Common Stock on the grant
date.

        ISOs  granted  to  persons  who own more than 10% of the total  combined
voting power of all classes of the Company's  stock will be limited in term to a
period not to exceed five  years,  and the  exercise  price may not be less than
110% of the fair market value of the Common Stock on the date of grant.

        Subject to vesting periods,  each option may be exercised at any time in
whole or in part in accordance with its terms. The vested portion of all options
granted  under the 1994 Plan  terminate  three months after  termination  of the
optionee's  relationship with the Company or, if such optionee is terminated for
cause (as  defined  in the 1994  Plan),  immediately  upon  termination,  unless
otherwise  determined  by the Plan  Administrator.  Termination  provisions  are
adjusted in the event of the optionee's disability or death.

        The  optionee  may not  transfer  the  options  except by will or by the
applicable  laws of descent and  distribution.  To the extent  permitted  by the
Code, the Plan  Administrator  may permit an optionee to designate a beneficiary
or transfer the option.

        Capital  Adjustments.  In the event of  certain  reorganizations,  stock
dividends,  stock split up, consolidation or similar change in the Common Stock,
the number and price per share of shares covered by unexercised  options will be
proportionately adjusted.

        Federal Income Tax Consequences. The following discussion summarizes the
material federal income tax consequences of participation in the 1994 Plan. This
discussion is general in nature and does not address  issues  related to the tax
circumstances of any particular  individual.  The discussion is based on federal
income  tax laws in effect on the date  hereof  and is,  therefore,  subject  to
possible future changes in law. This discussion does not address state, local or
foreign consequences.

        There are no tax  consequences  to the Company or the optionee  upon the
grant of an NSO  under the 1994  Plan.  Upon  exercise  of an NSO,  an  optionee
recognizes  ordinary  income equal to the difference  between the exercise price
for the shares and the fair market  value of the shares on the date of exercise.
The Company is entitled to a corresponding  tax deduction equal to the amount of
income recognized by the optionee,  provided that the deduction is not otherwise
disallowed by the Code,  including the  limitation on  deductibility  of certain
compensation payments in excess of $1 million.

                                       17
<PAGE>


        Upon grant or exercise of an ISO, an optionee does not recognize income,
except  that the  excess of the fair  market  value of the shares at the time of
exercise  over the option price will be income for purposes of  calculating  the
optionee's alternative minimum tax, if any. An option loses its status as an ISO
and becomes an NSO if the optionee  exercises the ISO (a) more than three months
after the optionee terminates employment or retires for reasons other than death
or disability or (b) more than one year after the optionee terminates employment
because  of  disability.   If  an  optionee  does  not  make  a   "disqualifying
disposition" (defined below) of an ISO, the gain, if any, upon a subsequent sale
(i.e.,  the  excess of the  proceeds  received  over the option  price)  will be
long-term capital gain.

        For  shares  acquired  through  exercise  of an  ISO,  a  "disqualifying
disposition" is a transfer of the shares (a) within two years after the grant of
the ISO or (b) within one year after the  transfer of the shares to the optionee
pursuant  to  the  ISO's  exercise.   If  the  optionee  makes  a  disqualifying
disposition,  the optionee  generally will  recognize  income in the year of the
disqualifying  disposition  equal to the excess of the amount  received  for the
shares over the option price. Of that income, the portion equal to the excess of
the fair market value of the shares at the time the ISO was  exercised  over the
option price will be ordinary income and the balance,  if any, will be long-term
or short-term capital gain,  depending on whether the shares were sold more than
one year after the ISO was exercised. If, however, the optionee sells the shares
to an  unrelated  party at a price  that is below the fair  market  value of the
shares  at the  time  the ISO was  exercised  and  the  sale is a  disqualifying
disposition,  the  amount of  ordinary  income  will be  limited  to the  amount
realized on the sale over the option price.

        The Company is entitled  to a deduction  with  respect to an ISO only in
the taxable year of the Company in which a disqualifying  disposition occurs. In
that  event,  the  deduction  would  be equal to the  ordinary  income,  if any,
recognized by the optionee  upon  disposition  of the shares,  provided that the
deduction is not otherwise  disallowed by the Code,  including the limitation on
deductibility of certain compensation payments in excess of $1 million.

        THE BOARD OF DIRECTORS RECOMMENDS A VOTE FOR APPROVAL OF THE PROPOSAL TO
AMEND THE RESTATED 1994 STOCK OPTION PLAN.

                             PROPOSALS OF SHAREHOLDERS

        Under the Company's Bylaws,  shareholders seeking to propose business to
be conducted at an annual  meeting of  shareholders  must give written notice to
the Company no later than the date shareholder nominations for Directors must be
received. The notice must contain certain information as to the proposal and the
shareholder,  including  the  shareholder's  share  ownership  and any financial
interest of the shareholder in the proposal. Any proposal not made in compliance
with the  Bylaws  may be  rejected  by the Board of  Directors.  No  shareholder
proposals for the Annual Meeting had been received by the Company as of the date
of this Proxy Statement.

                                       18
<PAGE>


        A  shareholder  who  intends to present a  proposal  at the 1998  Annual
Meeting of Shareholders and desires that  information  regarding the proposal be
included  in the 1998 proxy  statement  and form of proxy must  ensure that such
information is received by the Company no later than December 2, 1997.

                                  OTHER BUSINESS

        The Company  knows of no other  business to be  presented  at the Annual
Meeting.  If any other business properly comes before the Annual Meeting,  it is
intended  that the  shares  represented  by proxies  will be voted with  respect
thereto  in  accordance  with  the best  judgment  of the  persons  named in the
accompanying form of proxy.

        Upon written request from any person  solicited  herein addressed to the
Company's Corporate  Secretary at the Company's  principal offices,  the Company
will  provide,  at no cost, a copy of the  Company's  Form 10-K Annual Report as
filed with the SEC for the year ended December 31, 1996.

                                      BY ORDER OF THE BOARD OF DIRECTORS



                                      /s/ Richard L. Anderson
                                      -------------------------------------
                                      RICHARD L. ANDERSON
                                      Senior Vice President, Chief Financial
                                      Officer, Secretary and Treasurer

April 8, 1997
Seattle, Washington



                                       19
<PAGE>



                                                                      EXHIBIT  A

                                NEORX CORPORATION
                         RESTATED 1994 STOCK OPTION PLAN

                               SECTION 1. PURPOSE

         The purpose of the  Restated  1994 Stock Option Plan (the "Plan") is to
provide  a  means  whereby  selected  employees,  officers,  directors,  agents,
consultants,  advisors and  independent  contractors of NeoRx  Corporation  (the
"Company"),  or of any parent or subsidiary  (as defined in  subsection  5.8 and
referred to  hereinafter  as  "related  corporations")  thereof,  may be granted
incentive stock options and/or nonqualified stock options to purchase the Common
Stock (as defined in Section 3) of the  Company,  in order to attract and retain
the  services  or  advice  of  such  employees,   officers,  directors,  agents,
consultants, advisors and independent contractors and to provide added incentive
to such persons by encouraging stock ownership in the Company.

                            SECTION 2. ADMINISTRATION

         This  Plan  shall be  administered  by the  Board of  Directors  of the
Company  (the  "Board")  or a  committee  or  committees  (which  term  includes
subcommittees)  appointed  by, and  consisting  of two or more  members  of, the
Board. The  administrator  of this Plan shall  hereinafter be referred to as the
"Plan  Administrator."  So long as the Common Stock is registered  under Section
12(b) or 12(g) of the Securities Exchange Act of 1934, as amended (the "Exchange
Act"),  the Board shall consider,  in selecting the Plan  Administrator  and the
membership  of any  committee  acting  as Plan  Administrator  of this Plan with
respect to any persons  subject or likely to become  subject to Section 16 under
the  Exchange  Act,  the  provisions   regarding  (a)  "outside  directors,"  as
contemplated by Section 162(m) of the Internal  Revenue Code of 1986, as amended
(the "Code"),  and (b)  "nonemployee  directors," as  contemplated by Rule 16b-3
under  the  Exchange  Act.  The  Board  may  delegate  the   responsibility  for
administering   this  Plan  with  respect  to  designated  classes  of  eligible
participants to different  committees,  subject to such limitations as the Board
deems appropriate.  Committee members shall serve for such term as the Board may
determine, subject to removal by the Board at any time.

         2.1      Procedures

         The Board shall designate one of the members of the Plan  Administrator
as chairman.  The Plan  Administrator may hold meetings at such times and places
as it  shall  determine.  The  acts of a  majority  of the  members  of the Plan
Administrator  present at meetings at which a quorum exists,  or acts reduced to
or approved in writing by all Plan Administrator members, shall be valid acts of
the Plan Administrator.

         2.2      Responsibilities

         Except for the terms and conditions  explicitly set forth in this Plan,
the Plan Administrator shall have the authority, in its discretion, to determine
all matters  relating to the  options to be granted  under this Plan,  including
selection of the individuals to be granted  options,  the number of shares to be
subject to each option,  the exercise price,  and all other terms and conditions
of the  options.  Grants  under this Plan need not be  identical in any respect,
even when made  simultaneously.  The interpretation and construction by the Plan

                                      A-1
<PAGE>

Administrator  of any  terms or  provisions  of this Plan or any  option  issued
hereunder,  or of any rule or regulation  promulgated  in  connection  herewith,
shall be  conclusive  and  binding on all  interested  parties,  so long as such
interpretation   and  construction  with  respect  to  incentive  stock  options
correspond  to the  requirements  of Section  422 of the Code,  the  regulations
thereunder and any amendments thereto.

         2.3      Rule 16b-3 Compliance and Bifurcation of Plan

         Notwithstanding  anything in this Plan to the contrary,  the Board,  in
its absolute  discretion,  may bifurcate  this Plan so as to restrict,  limit or
condition the use of any provision of this Plan to participants  who are subject
to  Section  16  of  the  Exchange  Act  without  so  restricting,  limiting  or
conditioning this Plan with respect to other participants.

                      SECTION 3. STOCK SUBJECT TO THIS PLAN

         The stock subject to this Plan shall be the Company's Common Stock (the
"Common Stock"),  presently authorized but unissued or subsequently  acquired by
the  Company.  Subject to  adjustment  as provided  in Section 7, the  aggregate
amount of Common Stock to be delivered upon the exercise of all options  granted
under this Plan  shall not  exceed  4,000,000  shares as such  Common  Stock was
constituted on the effective date of this Plan. If any option granted under this
Plan shall expire or be surrendered,  exchanged for another option,  canceled or
terminated for any reason without having been exercised in full, the unpurchased
shares subject  thereto shall  thereupon again be available for purposes of this
Plan,  including  for  replacement  options which may be granted in exchange for
such expired, surrendered, exchanged, canceled or terminated options.

                             SECTION 4. ELIGIBILITY

         An incentive stock option may be granted only to any individual who, at
the time the option is  granted,  is an  employee  of the Company or any related
corporation.  A  nonqualified  stock  option  may be  granted  to any  employee,
officer,  director, agent, consultant,  advisor or independent contractor of the
Company or any related  corporation,  whether an  individual  or an entity.  Any
party to whom an  option  is  granted  under  this  Plan  shall be  referred  to
hereinafter as an "Optionee."

                   SECTION 5. TERMS AND CONDITIONS OF OPTIONS

         Options   granted  under  this  Plan  shall  be  evidenced  by  written
agreements  which  shall  contain  such  terms,   conditions,   limitations  and
restrictions  as the Plan  Administrator  shall deem advisable and which are not
inconsistent  with this  Plan.  Notwithstanding  the  foregoing,  options  shall
include or incorporate by reference the following terms and conditions:

         5.1      Number of Shares and Price

         The  maximum  number of shares  that may be  purchased  pursuant to the
exercise  of each  option  and the  price  per  share at which  such  option  is
exercisable  (the  "exercise  price")  shall  be  as  established  by  the  Plan
Administrator,  provided that the maximum number of shares with respect to which
an option or options  may be granted to any  Optionee  in any one fiscal year of
the Company  shall not exceed  500,000  shares  (the  "Maximum  Annual  Optionee
Grant");  and provided  that the Plan  Administrator  shall act in good faith to
establish the exercise  price which shall be not less than the fair market value
per share of the  Common  Stock at the time the  option  is  granted  and,  with
respect to incentive stock options granted to greater than 10% shareholders, the
exercise price shall be as required by subsection 6.1.

                                      A-2
<PAGE>


         5.2      Term and Maturity

         Subject to the  restrictions  contained  in  Section 6 with  respect to
granting  incentive stock options to greater than 10% shareholders,  the term of
each incentive  stock option shall be as  established by the Plan  Administrator
and, if not so established, shall be 10 years from the date it is granted but in
no event shall it exceed 10 years.  The term of each  nonqualified  stock option
shall be as established by the Plan  Administrator  and, if not so  established,
shall be 10 years.  To ensure  that the  Company or a related  corporation  will
achieve the purpose and receive  the  benefits  contemplated  in this Plan,  any
option  granted to any Optionee  hereunder  shall,  unless the condition of this
sentence  is waived or  modified in the  agreement  evidencing  the option or by
resolution  adopted  at any  time  by the  Plan  Administrator,  be  exercisable
according to the following schedule:
<TABLE>
<CAPTION>


                    Period of Optionee's Continuous
                     Relationship With the Company           Portion of Total
                    or Related Corporation From the          Option Which is
                      Date the Option is Granted                Exercisable
                    --------------------------------         ----------------- 
                           <S>                                     <C>
                           after one year                          25%
                           after two years                         50%
                           after three years                       75%
                           after four years                        100%
</TABLE>

Unless the Plan  Administrator  (or the Company's Chief Executive Officer in the
case of  optionees  who are not  subject to Section 16 under the  Exchange  Act)
determines  otherwise,  the  vesting  schedule  of an option  shall be  adjusted
proportionately  to the extent an Optionee's  hours of employment or service are
reduced after the date of grant.

         5.3      Exercise

         Subject to the vesting  schedule  described  in  subsection  5.2,  each
option may be  exercised  in whole or in part at any time and from time to time;
provided,  however,  that no fewer than 100 shares (or the remaining shares then
purchasable under the option, if less than 100 shares) may be purchased upon any
exercise of option  rights  hereunder  and that only whole shares will be issued
pursuant to the exercise of any option.  Options  shall be exercised by delivery
to the  Company  of notice of the  number of shares  with  respect  to which the
option is exercised, together with payment of the exercise price.

         5.4      Payment of Exercise Price

         Payment of the option  exercise price shall be made in full at the time
the notice of exercise of the option is delivered to the Company and shall be in
cash, bank certified or cashier's check or personal check (unless at the time of
exercise the Plan  Administrator in a particular case determines not to accept a
personal check) for the Common Stock being purchased.

         The Plan  Administrator  can determine at any time before exercise that
additional forms of payment will be permitted.  Unless the Plan Administrator in
its sole  discretion  determines  otherwise,  either  at the time the  option is
granted or at any time before it is  exercised,  and to the extent  permitted by
applicable laws and regulations (including,  but not limited to, federal tax and

                                      A-3
<PAGE>


securities  laws and  regulations  and state  corporate  law),  an option may be
exercised by a combination of cash and/or check and one or both of the following
alternative forms:

         (a) tendering  (either  actually or by attestation)  shares of stock of
the Company held by an Optionee having a fair market value equal to the exercise
price,  such  fair  market  value  to be  determined  in good  faith by the Plan
Administrator;  provided,  however,  that  payment in stock held by an  Optionee
shall not be made unless the stock shall have been owned by the  Optionee  for a
period of at least six months (or any shorter period necessary to avoid a charge
to the Company's earnings for financial accounting purposes); or

                  (b) delivery of a properly executed exercise notice,  together
with  irrevocable   instructions  to  a  broker,  all  in  accordance  with  the
regulations of the Federal Reserve Board, to promptly deliver to the Company the
amount of sale or loan proceeds to pay the exercise price and any federal, state
or local  withholding  tax  obligations  that may arise in  connection  with the
exercise.

         5.5      Withholding Tax Requirement

         The  Company may require the Holder to pay to the Company the amount of
any  withholding  taxes that the Company is required to withhold with respect to
the grant or exercise of any Award.  Subject to the Plan and applicable law, the
Plan  Administrator,  in its sole  discretion  may  permit a Holder  to  satisfy
withholding  obligations,  in whole or in part,  by paying cash,  by electing to
have the Company  withhold shares of Common Stock or by  transferring  shares of
Common  Stock to the  Company,  in such  amounts as are  equivalent  to the fair
market value of the withholding obligation.  The Company shall have the right to
withhold from any shares of Common Stock  issuable  pursuant to an Award or from
any  cash  amounts  otherwise  due or to  become  due from  the  Company  to the
Participant an amount equal to such taxes.

         5.6      Holding Periods

                  5.6.1       Securities and Exchange Act Section 16

         If an individual subject to Section 16 of the Exchange Act sells shares
of Common Stock  obtained  upon the exercise of a stock option within six months
after the date the  option  was  granted,  such sale may  result in  short-swing
profit liability under Section 16(b) of the Exchange Act.

                  5.6.2       Taxation of Stock Options

         In order to obtain  certain tax benefits  afforded to  incentive  stock
options  under  Section 422 of the Code, an Optionee must hold the shares issued
upon the exercise of an  incentive  stock option for two years after the date of
grant of the option and one year from the date of  exercise.  An Optionee may be
subject to the  alternative  minimum tax at the time of exercise of an incentive
stock option.

         The Plan  Administrator  may  require an  Optionee  to give the Company
prompt  notice of any  disposition  of shares of Common  Stock  acquired  by the
exercise of an incentive  stock option prior to the  expiration  of such holding
periods.

         Tax advice should be obtained when  exercising  any option and prior to
the disposition of the shares issued upon the exercise of any option.

                                      A-4 
<PAGE>


         5.7      Transferability of Options

         Options granted under this Plan and the rights and privileges conferred
hereby may not be transferred,  assigned,  pledged or hypothecated in any manner
(whether  by  operation  of law or  otherwise)  other  than  by  will  or by the
applicable  laws of  descent  and  distribution,  and  shall not be  subject  to
execution,  attachment or similar process.  During an Optionee's  lifetime,  any
options  granted under this Plan are personal to him or her and are  exercisable
solely by such  Optionee or a permitted  assignee or transferee of such Optionee
(as provided below).  Any attempt to transfer,  assign,  pledge,  hypothecate or
otherwise  dispose  of any option  under this Plan or of any right or  privilege
conferred hereby, contrary to the Code or to the provisions of this Plan, or the
sale or levy or any attachment or similar process upon the rights and privileges
conferred hereby shall be null and void.  Notwithstanding the foregoing,  to the
extent permitted by Section 422 of the Code, the Plan  Administrator  may permit
an Optionee to (i) during the  Optionee's  lifetime,  designate a person who may
exercise the option after the Optionee's  death by giving written notice of such
designation to the Company (such designation may be changed from time to time by
the  Optionee  by giving  written  notice to the  Company  revoking  any earlier
designation  and making a new  designation)  or (ii) transfer the option and the
rights and privileges conferred hereby;  provided,  however,  that any option so
assigned or  transferred  shall be subject to all the same terms and  conditions
contained in the instrument evidencing the award.

         5.8      Termination of Relationship

         If  the  Optionee's  relationship  with  the  Company  or  any  related
corporation  ceases for any reason,  then the portion of the  Optionee's  option
that  is  not  exercisable  at  the  time  of  such  cessation  shall  terminate
immediately  upon  such  cessation,  unless  the Plan  Administrator  determines
otherwise.  If the  Optionee's  relationship  with the  Company  or any  related
corporation  ceases for any reason other than  termination  for cause,  death or
total  disability,  and  unless by its terms the  option  sooner  terminates  or
expires, then the Optionee may exercise,  for a three-month period, that portion
of the Optionee's option which is exercisable at the time of such cessation, but
the Optionee's  option shall terminate at the end of such period  following such
cessation  as to all shares  for which it has not  theretofore  been  exercised,
unless such provision is waived in the agreement evidencing the option or at any
time prior to the expiration of the option by the Plan Administrator in its sole
discretion.  If, however, in the case of an incentive stock option, the Optionee
does not exercise the Optionee's  option within three months after  cessation of
employment, the option will no longer qualify as an incentive stock option under
the Code.

         If an Optionee is terminated for cause,  any option  granted  hereunder
shall  automatically  terminate as of the first  discovery by the Company of any
reason for  termination  for cause,  and such Optionee  shall  thereupon have no
right to purchase any shares  pursuant to such option.  "Termination  for cause"
shall  mean  dismissal  for  dishonesty,  conviction  or  confession  of a crime
punishable by law (except minor violations),  fraud, misconduct or disclosure of
confidential information.  If an Optionee's relationship with the Company or any
related  corporation is suspended pending an investigation of whether or not the
Optionee  shall be terminated  for cause,  all the  Optionee's  rights under any
option  granted  hereunder  likewise  shall be  suspended  during  the period of
investigation.

         If  an  Optionee's   relationship  with  the  Company  or  any  related
corporation ceases because of a total disability,  the portion of the Optionee's
option that is  exercisable at the time of such cessation may be exercised for a
period  of one year  following  such  cessation  (unless  by its terms it sooner
terminates  and  expires).  As used in this Plan,  the term  "total  disability"

                                      A-5
<PAGE>

refers to a mental or physical  impairment of the Optionee  which is expected to
result in death or which  has  lasted or is  expected  to last for a  continuous
period of 12 months or more and which causes the  Optionee to be unable,  in the
opinion of the Company  and two  independent  physicians,  to perform his or her
duties for the Company and to be engaged in any  substantial  gainful  activity.
Total  disability  shall be deemed to have  occurred  on the first day after the
Company and the two independent physicians have furnished their opinion of total
disability to the Plan Administrator.

         Any change of  relationship  with the Company  shall not  constitute  a
termination of the Optionee's relationship with the Company for purposes of this
Section  5.8 so long  as the  Optionee  continues  to be an  employee,  officer,
director  or,  pursuant  to a  written  agreement  with the  Company,  an agent,
consultant,  advisor or  independent  contractor  of the Company or of a related
corporation.  The Plan Administrator,  in its absolute discretion, may determine
all questions of whether  particular leaves of absence  constitute a termination
of services;  provided,  however,  that with respect to incentive stock options,
such determination  shall be subject to any requirements  contained in the Code.
The  foregoing  notwithstanding,   with  respect  to  incentive  stock  options,
employment  shall  not be deemed to  continue  beyond  the first 90 days of such
leave, unless the Optionee's reemployment rights are guaranteed by statute or by
contract.

         As used herein,  the term "related  corporation,"  when  referring to a
subsidiary corporation,  shall mean any corporation (other than the Company) in,
at the time of the  granting of the option,  an unbroken  chain of  corporations
ending with the Company,  if stock  possessing 50% or more of the total combined
voting power of all classes of stock of each of the corporations  other than the
Company is owned by one of the other  corporations in such chain. When referring
to  a  parent  corporation,  the  term  "related  corporation"  shall  mean  any
corporation in an unbroken chain of corporations  ending with the Company if, at
the time of the granting of the option,  each of the corporations other than the
Company owns stock  possessing 50% or more of the total combined voting power of
all classes of stock in one of the other corporations in such chain.

         5.9      Death of Optionee

         If an Optionee dies while he or she has a relationship with the Company
or any related  corporation or within the three-month period (or 12-month period
in  the  case  of  totally  disabled  Optionees)  following  cessation  of  such
relationship,  any option held by such  Optionee to the extent that the Optionee
would have been  entitled to exercise such option,  may be exercised  within one
year after his or her death by the personal  representative of his or her estate
or by the person or persons to whom the Optionee's rights under the option shall
pass (i) by will or by the applicable  laws of descent and  distribution or (ii)
by a designation or transfer pursuant to Section 5.7.

         5.10     No Status as Shareholder

         Neither the Optionee nor any party to which the  Optionee's  rights and
privileges  under the  option  may pass  shall be, or have any of the  rights or
privileges  of, a  shareholder  of the Company with respect to any of the shares
issuable  upon the  exercise  of any option  granted  under this Plan unless and
until such option has been exercised.

         5.11     Continuation of Relationship

         Nothing in this Plan or in any  option  granted  pursuant  to this Plan
shall  confer  upon any  Optionee  any right to  continue in the employ or other
relationship of the Company or of a related corporation,  or to interfere in any

                                      A-6
<PAGE>

way with  the  right  of the  Company  or of any  such  related  corporation  to
terminate his or her  employment or other  relationship  with the Company at any
time.

         5.12     Modification and Amendment of Option

         Subject  to the  requirements  of Code  Section  422  with  respect  to
incentive  stock  options  and  to the  terms  and  conditions  and  within  the
limitations of this Plan, the Plan Administrator may modify or amend outstanding
options granted under this Plan. The modification or amendment of an outstanding
option shall not, without the consent of the Optionee, impair or diminish any of
his or her rights or any of the  obligations  of the Company  under such option.
Except as  otherwise  provided  in this Plan,  no  outstanding  option  shall be
terminated without the consent of the Optionee.

         5.13     Limitation on Value for Incentive Stock Options

         As to all incentive stock options granted under the terms of this Plan,
to the extent that the aggregate  fair market value of the stock  (determined at
the time the incentive  stock option is granted) with respect to which incentive
stock  options are  exercisable  for the first time by the  Optionee  during any
calendar year (under this Plan and all other incentive stock option plans of the
Company, a related corporation or a predecessor  corporation)  exceeds $100,000,
such  options  shall be treated as  nonqualified  stock  options.  The  previous
sentence shall not apply if the Internal  Revenue  Service issues a public rule,
issues a private  ruling to the Company,  any Optionee or any legatee,  personal
representative or distributee of an Optionee or issues  regulations  changing or
eliminating such annual limit.

                    SECTION 6. GREATER THAN 10% SHAREHOLDERS

         6.1      Exercise Price and Term of Incentive Stock Options

         If incentive stock options are granted under this Plan to employees who
own more than 10% of the total combined  voting power of all classes of stock of
the Company or any related corporation, the term of such incentive stock options
shall not exceed five years and the  exercise  price shall be not less than 110%
of the fair market  value of the Common  Stock at the time the  incentive  stock
option is granted.  This provision  shall control  notwithstanding  any contrary
terms contained in an option agreement or any other document.

         6.2      Attribution Rule

         For purposes of subsection  6.1, in  determining  stock  ownership,  an
employee shall be deemed to own the stock owned,  directly or indirectly,  by or
for his or her brothers,  sisters,  spouse,  ancestors  and lineal  descendants.
Stock  owned,  directly or  indirectly,  by or for a  corporation,  partnership,
estate  or trust  shall be  deemed  to be  owned  proportionately  by or for its
shareholders,  partners or beneficiaries.  If an employee or a person related to
the  employee  owns an  unexercised  option or warrant to purchase  stock of the
Company,  the stock  subject to that  portion of the option or warrant  which is
unexercised shall not be counted in determining stock ownership. For purposes of
this  Section 6, stock owned by an  employee  shall  include all stock  actually
issued  and  outstanding  immediately  before the grant of the  incentive  stock
option to the employee.

                                      A-7
<PAGE>


              SECTION 7. ADJUSTMENTS UPON CHANGES IN CAPITALIZATION

         The  aggregate  number  and class of shares  for which  options  may be
granted under this Plan, the Maximum Annual  Optionee Grant set forth in Section
5.1, the number and class of shares covered by each  outstanding  option and the
exercise  price  per share  thereof  (but not the  total  price),  and each such
option,  shall all be  proportionately  adjusted for any increase or decrease in
the number of issued  shares of Common  Stock of the  Company  resulting  from a
split-up  or  consolidation  of shares or any like  capital  adjustment,  or the
payment of any stock dividend.

         7.1      Effect of Liquidation or Reorganization

         Upon  a  merger,  consolidation,  acquisition  of  property  or  stock,
separation,  reorganization or liquidation of the Company,  as a result of which
the  shareholders  of the  Company  receive  cash,  stock or other  property  in
exchange  for or in  connection  with  their  shares of Common  Stock  (each,  a
"corporate  transaction"),  then the  exercisability of each option  outstanding
under  this Plan shall be  automatically  accelerated  so that each such  option
shall,  immediately  prior to the  specified  effective  date for the  corporate
transaction, become fully exercisable with respect to the total number of shares
of Common Stock  purchasable  under such option and may be exercised  for all or
any portion of such shares. To the extent such option is not exercised, it shall
terminate,  except  that  in the  event  of a  corporate  transaction  in  which
shareholders  of the Company  receive  capital stock of another  corporation  in
exchange  for their shares of Common  Stock,  such  unexercised  option shall be
assumed  or  an  equivalent  option  shall  be  substituted  by  such  successor
corporation  or a parent or subsidiary of such successor  corporation.  Any such
assumed or  equivalent  option  shall be fully  exercisable  with respect to the
total number of shares purchasable under such option.

         Notwithstanding  the  foregoing,  upon a merger of the Company in which
the  holders  of Common  Stock  immediately  prior to the  merger  have the same
proportionate ownership of common stock in the surviving corporation immediately
after the merger, a mere  reincorporation  or the creation of a holding company,
each option outstanding under this Plan shall be assumed or an equivalent option
shall be substituted  by the successor  corporation or a parent or subsidiary of
such  corporation,  and  the  vesting  schedule  set  forth  in  the  instrument
evidencing  the option  shall  continue to apply to such  assumed or  equivalent
option.

         7.2      Fractional Shares

         In the event of any  adjustment in the number of shares  covered by any
option,   any  fractional   shares  resulting  from  such  adjustment  shall  be
disregarded  and each such  option  shall  cover only the number of full  shares
resulting from such adjustment.

         7.3      Determination of Board to Be Final

         All  Section  7  adjustments  shall  be  made  by the  Board,  and  its
determination  as to what  adjustments  shall be made,  and the extent  thereof,
shall be final, binding and conclusive. Unless an Optionee agrees otherwise, any
change or adjustment to an incentive stock option shall be made in such a manner
so as not to constitute a  "modification"  as defined in Code Section 425(h) and
so as not to cause his or her incentive stock option issued hereunder to fail to
continue  to qualify as an  incentive  stock  option as defined in Code  Section
422(b).

                                      A-8
<PAGE>


                        SECTION 8. SECURITIES REGULATION

         Shares shall not be issued with respect to an option granted under this
Plan unless the  exercise of such option and the  issuance  and delivery of such
shares  pursuant  thereto  shall  comply with all  relevant  provisions  of law,
including,  without  limitation,  any  applicable  state  securities  laws,  the
Securities Act of 1933, as amended,  the Exchange Act, the rules and regulations
promulgated  thereunder,  and the  requirements of any stock exchange upon which
the shares may then be listed,  and shall be further  subject to the approval of
counsel  for  the  Company  with  respect  to  such  compliance,  including  the
availability,  if applicable, of an exemption from registration for the issuance
and sale of any shares hereunder.

                      SECTION 9. AMENDMENT AND TERMINATION

         9.1      Board Action

         The  Board  may at any time  suspend,  amend or  terminate  this  Plan,
provided  that, to the extent  required for  compliance  with Section 422 of the
Code or by any  applicable law or regulation,  the Company's  shareholders  must
approve any amendment which will:

                  (a)  increase  the  total number of shares  that may be issued
                       under this Plan;

                  (b)  modify the class of  participants eligible for participa-
                       tion in this Plan; or

                  (c)  otherwise require shareholder approval under any appli-
                       cable law or regulation.

         Such  shareholder  approval must be obtained   within  12 months of the
adoption by the Board of such amendment.

         Any amendment made to this Plan since its original adoption which would
constitute a "modification"  to incentive stock options  outstanding on the date
of such amendment  shall not be applicable to such  outstanding  incentive stock
options,  but shall have  prospective  effect only,  unless the Optionee  agrees
otherwise.

         9.2      Automatic Termination

         Unless sooner  terminated by the Board,  this Plan shall  terminate ten
years  from the  earlier  of (a) the date on which  this Plan is  adopted by the
Board or (b) the date on which this Plan is approved by the  shareholders of the
Company.  No  option  may be  granted  after  such  termination  or  during  any
suspension of this Plan.  The amendment or  termination  of this Plan shall not,
without  the  consent of the option  holder,  impair or  diminish  any rights or
obligations under any option theretofore granted under this Plan.

                     SECTION 10. EFFECTIVENESS OF THIS PLAN

         This Plan shall become  effective upon adoption by the Board so long as
it is approved by the Company's shareholders at any time within 12 months of the
adoption of this Plan or, if earlier and to the extent  required for  compliance
with  Rule  16b-3  under  the  Exchange  Act,  at the  next  annual  meeting  of
shareholders after adoption by the Board.

                                      A-9
<PAGE>

PROXY

                               NEORX CORPORATION

                  PROXY FOR THE ANNUAL MEETING OF SHAREHOLDERS
                            TO BE HELD MAY 13, 1997

          THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

The undersigned hereby appoints Richard L. Anderson as Proxy, with full power of
substitution,  and hereby authorizes him to represent and to vote, as designated
below, all the shares of Common Stock of NeoRx Corporation held of record by the
undersigned on March 28, 1997, at  the Annual Meeting of Shareholders to be held
on May 13, 1997, or any adjournment or postponement thereof.

                  (Continued and to be signed on reverse side)

                                                           Please mark your vote
                                                           as indicated in this
                                                           example  [X]

1. ELECTION OF DIRECTORS

                        FOR                   WITHHOLD
                   all nominees               AUTHORITY
                 (except as marked          to vote for all
                  to the contrary).             nominees.

                      [ ]                        [ ]


Election of the  following  six nominees to serve as  Directors  for the ensuing
year or until their  successors  are elected and  qualified:  
Nominees:  Paul G. Abrams, James G. Andress,
           Jack L. Bowman, Fred B. Craves,
           Lawrence H.N. Kinet and Carl-Heinz Pommer.

INSTRUCTIONS:  To withhold authority to vote for any individual nominee, write
the name(s) of the nominee(s) below:

________________________________________________________________
Unless otherwise directed, all voted will be apportioned equally
among those persons for whom authority is given to vote.

2.  RATIFICATION OF INDEPENDENT PUBLIC ACCOUNTANTS

                   FOR           AGAINST           ABSTAIN

                   [ ]             [ ]               [ ]

Ratify the appointment of KPMG Peat Marwick LLP as independent public 
accountants of NeoRx Corporation for the year 1997.

3.  STOCK OPTION PLAN

                  FOR           AGAINST           ABSTAIN

                  [ ]             [ ]               [ ]
                  

Consider  and approve an increase in the number of shares  issuable  under NeoRx
Corporation's Restated 1994 Stock Option Plan from 2,500,000 to 4,000,000.

In their discretion, the Proxy is authorized to vote upon such other business as
may properly come before the meeting.  This Proxy, when properly executed,  will
be voted in the manner  directed herein by the  undersigned.
IF NO DIRECTION IS MADE,  THIS PROXY WILL BE VOTED "FOR ALL  NOMINEES" IN ITEM 1
AND "FOR" IN ITEMS 2 AND 3.

YOUR VOTE IS  IMPORTANT.  PROMPT  RETURN OF THIS  PROXY  CARD WILL HELP SAVE THE
EXPENSE OF ADDITIONAL SOLICITATION EFFORTS.

Signature(s)____________________________________________Dated:______________1997
Please sign above exactly as your name appears on your stock  certificate.  When
shares are held  jointly,  each person  should  sign.  When signing as attorney,
executor, administrator, trustee or guardian, please give full title as such. An
authorized  person  should  sign on behalf  of  corporations,  partnerships  and
associations and give his or her title.


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