NEORX CORP
DEF 14A, 1998-04-09
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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================================================================================

                     INFORMATION REQUIRED IN PROXY STATEMENT
                             ----------------------
                            SCHEDULE 14A INFORMATION

Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

                Filed by the Registrant (X)
                Filed by a Party other than the Registrant  ( )

                           Check the appropriate box:
              ( )  Preliminary Proxy Statement
              ( )  Confidential, For Use of the Commission Only
                   (as permitted by Rule 14a-6(e)(2))
              (X)  Definitive Proxy Statement
              ( )  Definitive Additional Materials
              ( )  Soliciting Material Pursuant to Rule 14a-11(c) or Rule 14a-12

                                NEORX CORPORATION
                (Name of Registrant as Specified in Its Charter)

Payment of Filing Fee (Check the appropriate box):
(X)  No fee required.
( )  Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11.


CALCULATION OF FILING FEE
Title of each class of securities to which transaction applies:
Aggregate number of securities to which transaction applies:
Per unit price or other underlying value of transaction computed pursuant to
Exchange Act Rule 0-11:
Proposed maximum aggregate value of transaction:
Total fee paid:

( )  Fee paid previously with preliminary materials:
( )  Check  box if any part of the fee is offset as provided by Exchange Act
     Rule 0-11(a)(2) and identify the filing for which the offsetting fee was
     paid previously. Identify the previous filing by registration statement
     number, or the form or schedule and the date of its filing.

       Amount previously paid:
                               --------------------------
       Form, Schedule or
       Registration Statement no.:
                                  -----------------------
       Filing Party:
                    -------------------------------------
       Date Filed:
                   --------------------------------------
================================================================================
<PAGE>
                                NEORX CORPORATION

                  Notice of 1998 Annual Meeting of Shareholders

TO THE SHAREHOLDERS:

         The 1998 Annual Meeting of Shareholders (the "Annual Meeting") of NeoRx
Corporation  (the  "Company") will be held at The  Mountaineers  Club, 300 Third
Avenue West, Seattle,  Washington 98119, on Wednesday,  May 13, 1998, at 9 a.m.,
for the following purposes:

         1.       To elect six members to the Company's Board of Directors;

         2.       To transact such other business as may properly come before
                  the Annual Meeting and any adjournments or postponements
                  thereof.

         Your  attention is directed to the  accompanying  Proxy  Statement  for
further  information  with respect to the matters to be acted upon at the Annual
Meeting.  To  constitute  a quorum  for the  conduct of  business  at the Annual
Meeting, it is necessary that holders of a majority of all outstanding shares of
the Company's  Common Stock be present in person or be represented by proxy.  To
ensure representation at the Annual Meeting, you are urged to complete, sign and
date  the   enclosed   proxy  card  and  return  it  promptly  in  the  enclosed
postage-prepaid envelope.

         The record date for determining shareholders entitled to notice of, and
to vote at, the Annual Meeting is the close of business on March 16, 1998.

                                   BY ORDER OF THE BOARD OF DIRECTORS





                                   RICHARD L. ANDERSON
                                   Senior Vice President, Finance and Operations
                                   Chief Financial Officer, Secretary

March 24, 1998
Seattle, Washington


         YOUR VOTE IS IMPORTANT.  ACCORDINGLY,  YOU ARE ASKED TO COMPLETE, SIGN,
DATE AND RETURN THE  ACCOMPANYING  PROXY CARD  REGARDLESS  OF WHETHER OR NOT YOU
PLAN TO ATTEND THE ANNUAL MEETING.


<PAGE>




                                NEORX CORPORATION
                                 PROXY STATEMENT

General

         This Proxy Statement is furnished in connection  with the  solicitation
by the Board of  Directors  (the  "Board  of  Directors")  of NeoRx  Corporation
("NeoRx" or the  "Company") of proxies in the  accompanying  form for use at the
Annual Meeting of  Shareholders  to be held on Wednesday,  May 13, 1998, and any
adjournments or postponements thereof (the "Annual Meeting"). The Annual Meeting
will be held at 9 a.m. at The Mountaineers Club, 300 Third Avenue West, Seattle,
Washington 98119.

         The Company's  principal office is located at 410 West Harrison Street,
Seattle,  Washington 98119. The approximate date of mailing this Proxy Statement
and the accompanying proxy card is March 27, 1998.

Voting Securities

         Only shares of the  Company's  Common  Stock,  $.02 par value per share
(the "Common  Stock"),  outstanding  at the close of business on March 16, 1998,
the record date for determining  shareholders (the "Record Date"),  are entitled
to receive  notice of and to vote at the  Annual  Meeting.  At the Record  Date,
there were  20,720,414  shares of Common Stock  outstanding.  The  presence,  in
person or by proxy of holders of record of a majority, of all outstanding shares
of Common  Stock is  required  to  constitute  a quorum for the  transaction  of
business  at the  Annual  Meeting.  Each  holder  of Common  Stock is  generally
entitled  to one vote per share held on the Record Date on each item to be voted
on at the Annual Meeting. In voting for the election of Directors, however, each
shareholder has the right to cumulate his or her votes and cast as many votes as
are equal to the number of Directors to be elected  multiplied  by the number of
such  shareholder's  shares.  These  votes  may be  cast  for one  candidate  or
distributed  among  as  many  candidates  as  the  shareholder   desires.  If  a
shareholder  wishes to cumulate his or her votes,  he or she should multiply his
or her shares by the number of  Directors  to be elected  (deriving a cumulative
total)  and then  write  the  number  of votes  for each  Director  next to each
Director's  name on the proxy card.  The total votes cast in this manner may not
exceed the cumulative  total.  If a shareholder  does not wish to cumulate votes
for Directors,  he or she should  indicate the vote for or against each nominee,
as provided on the proxy card. On all other matters,  each share of Common Stock
entitles  its  holder to one vote on each  matter to be acted upon at the Annual
Meeting.

         Under Washington law and the Company's Articles of Incorporation,  if a
quorum is  present at the Annual  Meeting,  the six  nominees  for  election  as
Directors  who receive  the  greatest  number of votes cast for the  election of
Directors by the shares  present in person or represented by proxy at the Annual
Meeting and entitled to vote, will be elected Directors.  Abstention from voting
on the election of Directors will have no impact on the outcome of this proposal
since no vote has been  cast in favor of any  nominee.  There  can be no  broker
nonvotes on the  election of Directors  since  brokers who hold shares for their
clients  have  discretionary  authority to vote such shares with respect to this
matter.

                                       1
<PAGE>


         The proxy cards also confer discretionary  authority to vote the shares
authorized  to be voted  thereby on any matter that was not known on the date of
this Proxy  Statement  but may  properly be  presented  for action at the Annual
Meeting.

         YOUR VOTE IS IMPORTANT.  ACCORDINGLY,  YOU ARE ASKED TO COMPLETE, SIGN,
DATE AND RETURN THE  ACCOMPANYING  PROXY CARD  REGARDLESS  OF WHETHER OR NOT YOU
PLAN TO ATTEND THE ANNUAL MEETING.

Revocation

         Any  shareholder  returning  a proxy  has the power to revoke it at any
time before  shares  represented  thereby are voted at the Annual  Meeting.  Any
shares  represented by an unrevoked  proxy will be voted unless the  shareholder
attends the Annual Meeting and votes in person. A shareholder's  right to revoke
a proxy is not  limited by or  subject to  compliance  with a  specified  formal
procedure,  but  written  notice  of such  revocation  should  be  given  to the
Company's Corporate Secretary at or before the Annual Meeting.

Expenses of Solicitation

         The  Company  will bear the  expense  of  printing  and  mailing  proxy
solicitation  material.  In  addition  to the  solicitation  of proxies by mail,
solicitation may be made by certain  Directors,  officers and other employees of
the  Company  in  person,  by  telephone  or  by  facsimile   transmission.   No
compensation will be paid for such solicitation.

         Arrangements   also  will  be  made  with  brokerage  firms  and  other
custodians,  nominees and fiduciaries to forward proxy solicitation  material to
certain  beneficial  owners of the Company's  Common Stock, and the Company will
reimburse  such  brokerage  firms,  custodians,  nominees  and  fiduciaries  for
reasonable out-of-pocket expenses incurred by them in connection therewith.

                                       2

<PAGE>



         SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

         The following table sets forth certain information regarding beneficial
ownership,  as of March 3, 1998, of the Common Stock by (a) each person known by
the Board of  Directors  to  beneficially  own more  than 5% of the  outstanding
Common  Stock,  (b) each  Director  and  nominee for  Director,  (c) each of the
executive  officers  included in the  Summary  Compensation  Table,  and (d) all
executive officers and Directors as a group. Except as otherwise indicated,  the
Company believes that the beneficial owners of the shares listed below have sole
investment and voting power with respect to the shares.

<TABLE>
<CAPTION>
                                                                               Shares            Percentage
                                                                            Beneficially          of Common
         Name                                                                  Owned                Stock
         ----                                                               -------------        -----------
<S>                                                                          <C>                     <C>
Merrill Lynch Asset Management.......................................        1,889,375               9.1%
     800 Scudders Mill Road
     Plainsboro, New Jersey  08536

Ross Financial Corporation...........................................        1,196,000               5.8%
     Micro Commerce Center
     Cayman Islands B.W.I.

Paul G. Abrams (1)...................................................          584,672               2.8%

Richard L. Anderson (2)..............................................           56,250               *

James G. Andress (3).................................................           20,000               *

Jack L. Bowman (4)...................................................           24,000               *

Fred B. Craves (5)...................................................        1,182,500               5.7%

E. Rolland Dickson...................................................                0               *

Mary C. Foerster.....................................................                0               *

Lawrence H.N. Kinet (3)..............................................           17,500               *

Carl-Heinz Pommer (6)................................................           17,500               *

John M. Reno (7).....................................................          174,012               *

Robert W. Schroff (8)................................................          167,336               *

Alan Steigrod........................................................                0               *

Bruce H. Walters (9).................................................          119,175               *

All executive officers and Directors as a group (14 persons) (10)....        2,439,138              11.1%
- ------------------
<FN>
 * Less than 1%.
(1) Includes 450,500 shares subject to options  exercisable  within 60 days.
(2) Represents  56,250 shares  subject to options  exercisable  within 60 days.
(3) Includes  15,000  shares  subject to  options  exercisable  within 60 days.
(4) Includes 22,500 shares subject to options exercisable within 60 days.
(5) Represents 172,500 shares subject to options  exercisable within 60 days,
    and  includes 1,010,000  shares held by Bay City Capital Management, LLC.
    Mr. Craves is  the Chairman, Manager  and  Managing  Director of Bay City
    Capital Management, LLC and disclaims beneficial ownership.



                                       3

<PAGE>
(6) Represents 17,500 shares subject to options  exercisable  within 60 days,
    but  does not  include  731,534  shares  owned  by  Boehringer  Ingelheim
    International GmbH for which Mr. Pommer serves as a representative on the
    Board of Directors;  Mr.  Pommer  disclaims  beneficial  ownership of the
    shares held by Boehringer Ingelheim International GmbH.
(7) Includes 155,125 shares subject to options  exercisable  within 60 days.
(8) Includes  147,625  shares  subject to options  exercisable  within 60 days.
(9) Includes  110,500 shares  subject to options  exercisable  within 60 days.
(10)Includes 1,236,688 shares subject to options exercisable within 60 days.
</FN>
</TABLE>




                              ELECTION OF DIRECTORS

Nominees for Director

         Pursuant to the Company's Articles of Incorporation,  six Directors are
to be  elected  by the  holders of Common  Stock at the  Annual  Meeting.  These
Directors  will serve one-year terms that will expire at the 1999 Annual Meeting
of  Shareholders,  or until their  successors  have been elected and  qualified.
Unless a shareholder withholds his or her vote, each proxy will be voted for the
election of the following Directors:

         PAUL G. ABRAMS,  M.D., J.D., age 50, is a co-founder of the Company and
has been a Director since January 1985. He has been the Company's  President and
Chief Executive  Officer since May 1990 and was Vice President,  Medical Affairs
from January 1985 to April 1990.  Dr. Abrams holds J.D.,  M.D. and B.A.  degrees
from Yale University.  He is a board-certified  internist and medical oncologist
and is an Affiliate  Associate  Professor in the  Department of Radiology at the
University  of  Washington.  Dr.  Abrams serves on the Board of Directors of the
Biotechnology  Industry  Organization and is a member of its Emerging  Companies
Section Board.

     JACK L. BOWMAN,  age 66, has been a Director since January 1994. Mr. Bowman
was Company Group Chairman of Johnson & Johnson, a multinational  pharmaceutical
company,  from 1987 until his  retirement  in 1993.  Mr. Bowman is a director of
Cell  Therapeutics,   Inc.,  CytRx,  Inc.,  Vaxcel,   Inc.,   Targeted  Genetics
Corporation,  Osiris Therapeutics,  Inc., and Cellegy  Pharmaceuticals,  each of
which  is a  biotechnology  company.  He  holds  a  B.Ed.  degree  from  Western
Washington  University.

     FREDERICK B. CRAVES,  Ph.D., age 52, has been the Company's Chairman of the
Board of Directors  since July 1993. In June 1997,  Dr. Craves  founded Bay City
Capital  Management  LLC,  a  merchant  bank  providing  advisory  services  and
investing  in life  science  companies,  and has served as chairman and managing
director  since that company's  inception.  In November 1996, Dr. Craves founded
The Craves Group LLC;  and in January  1994,  Dr.  Craves  co-founded  Burrill &
Craves.  Both of these entities are investment  companies.  From January 1991 to
April 1993, he was Chief Executive Officer and President of Berlex  Biosciences,
a  research,  development  and  manufacturing  organization  and a wholly  owned
subsidiary  of  Schering  AG, a  multinational  pharmaceutical  company.  Berlex
Biosciences  was created by merging  Codon,  a  biotechnology  company which Dr.
Craves co-founded,  and the pharmaceutical  business of Triton Biosciences.  Dr.
Craves is  Chairman  of the Board and Acting  Chief  Executive  Officer of Epoch
Pharmaceuticals,  and  is a  director  of  Incyte  Pharmaceuticals,  Inc.,  both
biotechnology  companies.  Dr. Craves holds a Ph.D.  degree in Pharmacology  and
Experimental  Toxicology from the University of California San Francisco Medical
Center.

                                       4
<PAGE>

        E.ROLLAND DICKSON, M.D.,age 64, has been the Mary Lowell Leary Professor
of Medicine at Mayo  Medical  School and  Director  of  Development  at the Mayo
Foundation for Medical  Education and Research since 1993. Dr. Dickson  received
his M.D. degree from Ohio State University.

        MARY  C.  FOERSTER,  age  51,  is  Director  of  Public  Relations  and
Advertising for Boeing  Commercial  Airplane Group  worldwide.  Prior to joining
Boeing,  she was  employed  in the  public  relations  industry  with the global
communications  agencies  Burson-Marsteller,  where  she  served on the Board of
Directors,  and Hill &  Knowlton,  where she was Senior Vice  President,  Public
Affairs  Worldwide.  She  graduated  from Smith  College and  obtained a masters
degree from the University of Pennsylvania.

         ALAN A. STEIGROD,  age 60, has been Chief Executive  Officer of Newport
HealthCare  Ventures,  which provides  consulting and investment  service to the
biopharmaceutical  industry,  since 1996.  From March 1993 to November  1995, he
served as President and Chief Executive Officer of Cortex  Pharmaceuticals Inc.,
a development stage neuroscience company.

         It is intended that votes will be cast  pursuant to the enclosed  proxy
card for the election as  Directors of the  foregoing  nominees.  Executing  the
proxy  card  will  give the  proxies  the  authority  to vote the  shares in the
election of Directors as the proxies shall  determine.  If any nominee shall not
be a candidate for election as a Director at the Annual Meeting,  it is intended
that votes  will be cast  pursuant  to the  enclosed  proxy for such  substitute
nominee as may be nominated  by the existing  Directors.  No  circumstances  are
presently known that would render any nominee named above unavailable.

         Pursuant  to the  Company's  Bylaws,  shareholders  seeking to nominate
other  candidates  for election to the Board of Directors at the Annual  Meeting
must give written notice to the Company's  Corporate  Secretary not less than 60
days nor more than 90 days before the Annual  Meeting.  Such notice must contain
certain  information as to the  shareholder  giving the notice and each proposed
nominee,  including information similar to that required under the federal proxy
rules.  If less than 70 days' notice or prior public  disclosure  of the date of
the scheduled  Annual Meeting is given,  notice by the shareholder must be given
not later than the tenth day  following  the earlier of the mailing of notice of
the Annual Meeting or the date public disclosure of the Annual Meeting was made.
The Company's  Bylaws  provide that no person shall be elected a Director of the
Company unless  nominated in accordance with the Bylaws.  As of the date of this
Proxy  Statement,  the Company has not  received  any  Director  nominations  by
shareholders.

         The Board of Directors met 11 times during the year ended  December 31,
1997. Each of the present Directors, except Mr. Pommer, attended at least 75% of
the total number of meetings  held by the Board of  Directors  and by all of the
committees of the Board of Directors on which they served.

                                       5
<PAGE>


Committees of the Board

         The Board of Directors has two committees:  an Audit Committee and a
         Compensation  Committee. It does not have a nominating committee.

         The Audit Committee currently consists of three non-employee Directors:
Messrs.  Kinet and  Pommer,  and Dr.  Craves.  The Audit  Committee  reviews the
preparation  and audit of the Company's  accounts,  considers the  engagement of
independent  public  accountants  for the  ensuing  year  and the  terms of such
engagement,  reviews the scope of the audit  proposed by such  accountants,  and
receives and reviews the audit reports. The Audit Committee met twice during the
year ended December 31, 1997.

         The Compensation  Committee  currently  consists of three  non-employee
Directors:  Messrs.  Andress,  Bowman  and  Kinet.  The  Compensation  Committee
recommends  to the Board of Directors the salary and certain terms of employment
of the Company's  officers and  administers the Company's 1994 Stock Option Plan
and the grants of options thereunder.  The Compensation  Committee met ten times
during the year ended December 31, 1997.

Compensation of Directors

         Directors  of the  Company  receive  no  cash  compensation  for  their
services to the Company in such capacity.  Non-employee  Directors receive stock
option  grants  under the  Company's  1991 Stock  Option  Plan for  Non-Employee
Directors (the "Directors Plan"). Each new non-employee Director,  upon election
or appointment to the Board of Directors, receives an initial option to purchase
10,000  shares of Common  Stock at an  exercise  price  equal to the fair market
value per share of Common Stock on the grant date.  Each  non-employee  Director
automatically receives an annual option grant to purchase 5,000 shares of Common
Stock  following each annual meeting of  shareholders at an exercise price equal
to the fair market value per share of Common  Stock on the grant date,  provided
that a  non-employee  Director  who has  received  the initial  grant for 10,000
shares of Common Stock  within five months  prior to any such annual  meeting of
shareholders,  does not receive the annual  grant for such  annual  meeting.  In
February 1998, the Board of Directors  voted to increase the grant of options to
Directors  to 20,000 for the  initial  option and 10,000  shares at each  annual
meeting  date.  Options  granted to  non-employee  Directors  upon their initial
appointment or election become exercisable in two equal  installments  beginning
with the first  anniversary  of the grant date.  The options  granted as of each
annual meeting of shareholders (including the Annual Meeting) become exercisable
in two  equal  installments  on the  dates  of the next  two  succeeding  annual
meetings of shareholders.

         On February 21, 1997, the Board of Directors  granted to Dr.  Frederick
B. Craves an option to purchase 60,000 shares of the Company's Common Stock from
the Restated 1994 Stock Option Plan for his services as Chairman of the Board of
Directors.  In addition,  Dr. Craves  receives  compensation  under a consulting
agreement   with  the   Company.   See   "Certain   Relationships   and  Related
Transactions."
                                       6



<PAGE>



                             EXECUTIVE COMPENSATION

Compensation Summary

         The following table sets forth all compensation  for services  rendered
in each of the last three years to the Company's Chief Executive Officer and the
four  current  most highly  compensated  officers in 1997 (the "named  executive
officers").
<TABLE>
<CAPTION>

                                          Summary Compensation Table

                                                                              Long-Term
                                            Annual Compensation           Compensation  Awards
                                      --------------------------------   -----------------------
                                                             Bonus and   Restricted   Securities     All Other
                                                            Achievement     Stock     Underlying   Compensation
Name and Principal Position           Year      Salary($)   Award($)(2)   Awards($)   Options(#)      ($)(3)
- ----------------------------          ----      ---------   -----------  -----------  ----------   ------------

<S>                                   <C>       <C>           <C>            <C>        <C>           <C>
Paul G. Abrams                        1997      $274,149      $ 69,000       --              --       $  696
President and Chief Executive         1996       258,457         1,700       --         125,000          696
Officer                               1995       234,149          --         --              --          696

Richard L. Anderson (1)               1997       184,141        64,663       --         242,500        1,500
Senior Vice President,                1996            --            --       --              --           --
Finance and Operations, and           1995            --            --       --              --           --
Chief Financial Officer

John M. Reno                          1997       169,718        75,262       --          30,000        1,152
Vice President, Research and          1996       169,718         1,700       --          25,000        1,152
Development                           1995       163,746            --       --              --          680

Robert W. Schroff                     1997       169,718        77,345       --          30,000        1,152
Vice President and General            1996       157,925         1,700       --          25,000          336
Manager, Cardiovascular               1995       152,498            --       --              --          321
Products

Bruce H. Walters                      1997       137,551        35,000       --              --          908
Vice President, Human                 1996       137,551         1,700       --          25,000          908
Resources                             1995       135,917         1,389       --              --          894
<FN>

(1)      Mr. Anderson joined the Company on January 24, 1997.

(2)     Includes accrued bonus and achievement awards.

(3)     Consists of premiums paid under group term life insurance policies.
</FN>
</TABLE>

                                       7

<PAGE>



Stock Options

         The following table provides details regarding stock options granted to
the named executive officers in 1997. In addition, in accordance with Securities
and Exchange  Commission (the "SEC") rules,  the  hypothetical  gains or "option
spreads" that would exist for the respective  options are shown. These gains are
based on assumed rates of annual  compounded stock price  appreciation of 5% and
10% from the date the options were granted over their 10-year term.
<TABLE>
<CAPTION>

                                               OPTIONS GRANTED IN 1997

                                                                                Potential Realizable Value At
                                                                             Assumed Annual Rates of Stock Price
                                     Individual Grants                         Appreciation for Option Term
                    -------------------------------------------------------  ------------------------------------
                     Number of       Percent of
                     Securities     All Options
                     Underlying      Granted to     Exercise
                      Options        Employees        Price      Expiration
    Name            Granted(#)(1)     in 1997     Per Share($)      Date           5%($)(3)         10%($)(3)
- ------------------- ------------    -----------   ------------   ----------        --------         ---------
<S>                     <C>             <C>         <C>           <C>              <C>             <C>
Paul G. Abrams             --            --           --             --                --               --

Richard L. Anderson     202,500(2)      35.2%       $4.625        1/24/2007        $588,999        $1,492,640
                         10,000          1.7         4.4375       8/11/2007          27,907            70,721
                         30,000          5.2         5.75         12/2/2007         108,484           274,921
                        -------         ----                                       --------        ----------
                        242,500         42.2                                        725,390         1,838,282

John M. Reno             30,000          5.2         4.4375       8/11/2007          83,722           212,167

Robert W. Schroff        30,000          5.2         3.563        5/27/2007          67,198           170,316

Bruce H. Walters           --            --           --             --                --               --

<FN>

(1)    The Options granted will be exercisable in four equal annual installments
       beginning on the first anniversary date of the option and expire 10 years
       from the date of grant.  All options were granted with an exercise  price
       equal to the fair  market  value of the  Common  Stock on the date of the
       grant  based on the  closing  price of the Common  Stock as quoted on the
       Nasdaq  National  Market.  The  options are also  subject to  accelerated
       vesting upon the occurrence of certain events. See "Employment and Change
       of Control Agreements and Severance Agreement."

(2)    Of the 202,500 options granted to Mr. Anderson, 22,500 become exercisable
       on the sixth  anniversary  of the grant date and expire 10 years from the
       grant  date.  Exercisability  may  be  accelerated  by  the  Compensation
       Committee of the Board of Directors based on the  Committee's  assessment
       of the corporate performance against goals established annually.

(3)    The amounts  result from the  assumed  rates of stock price  appreciation
       required by the SEC and are not  intended to forecast  actual stock price
       appreciation.  Option  holders will  experience  no gain unless the stock
       price  increases  during the option term.  Such an increase would benefit
       all shareholders.
</FN>
</TABLE>
                                       8


<PAGE>



Option Exercises in 1997 and Year-End Value Table

         The following table sets forth  information on option  exercises in the
year ended  December 31, 1997 by the named  executive  officers and the value of
such officers' unexercised options at the end of 1997.
<TABLE>
<CAPTION>

                                     AGGREGATED OPTION EXERCISES IN 1997
                                          AND YEAR-END OPTION VALUES


                                                          Number of Securities          Value of Unexercised In-
                                                      Underlying Unexercised Options      The Money Options at
                                                         at December 31, 1997(#)         December 31, 1997($)(1)
                          Acquired on       Value     ------------------------------   ---------------------------
          Name            Exercise(#)    Realized($)   Exercisable   Unexercisable     Exercisable   Unexercisable
- -----------------------   -----------    -----------   -----------   -------------     ------------  -------------

<S>                               <C>           <C>        <C>           <C>           <C>              <C>
Paul G. Abrams                    --            --         450,500       240,000       $1,032,789       $392,974

Richard L. Anderson (2)           --            --          11,250       231,250           11,250        203,125

John M. Reno                      --            --         155,125        88,625          208,578        136,052

Robert W. Schroff                 --            --         147,625        86,125          208,578        162,287

Bruce H. Walters                  --            --         110,500        37,000          184,370         49,038
- --------------
<FN>

(1)    The value of unexercised  in-the-money options is calculated based on the
       market  price per share on December 31, 1997 of $5.625 as reported by the
       Nasdaq National Market, less the exercise price.

(2)    Mr. Anderson joined the Company on January 24, 1997.
</FN>
</TABLE>


Report of the Compensation Committee on Executive Compensation


Statement of Compensation Philosophy

         The Company's  executive  compensation  program  primarily  consists of
three parts: base salary, annual bonus, and stock options. The Company's overall
philosophy  is to  hire  individuals  who  possess  the  requisite  professional
managerial skills with demonstrated success in positions of comparable scope and
responsibility  in healthcare and other research and  industrial  settings,  who
will help achieve the Company's mission of developing innovative pharmaceuticals
to provide  solutions  for  critical,  unmet needs in cancer and  cardiovascular
diseases.  The Company is  committed to  recruiting,  motivating  and  retaining
senior executives with demonstrated talent and managerial leadership skills.

         The Company's goal for total  compensation  is to be  competitive  with
other  biotechnology  enterprises.  The program places  significant  emphasis on
equity  participation by granting stock options to align the interests of senior
management  with  those  of  the  Company's  shareholders.  The  Company's  cash
compensation  is designed to be competitive  while also  recognizing the need to
conserve cash for product development.

         Compensation  payments  in  excess of $1  million  to each of the named
executive  officers are subject to a limitation on deductibility for the Company
under Section 162(m) of the Internal  Revenue Code of 1986, as amended.  Certain
performance-based   compensation   is  not   subject   to  the   limitation   on

                                       9
<PAGE>

deductibility.  Cash  compensation to the Chief  Executive  Officer or any other
executive  officer has never exceeded $1 million and the Compensation  Committee
does not expect cash  compensation in 1998 to the Chief Executive Officer or any
other executive officer to exceed $1 million.  The Board of Directors intends to
qualify  option  awards for the  performance-based  exception  to the $1 million
limitation on deductibility of compensation payments.

Base Salary

         The Company's  philosophy is to maintain executive cash compensation at
a competitive level sufficient to recruit and retain individuals  possessing the
above-mentioned  skills.  Determinations of appropriate cash compensation levels
are generally made through  regular  participation  in a variety of industry and
industry-related   surveys,  as  well  as  by  monitoring  developments  in  key
industries  such  as  biotechnology  and  pharmaceuticals.  The  Company's  cash
compensation  levels are designed to be approximately equal to cash compensation
paid by other biotechnology  enterprises.  For the last several years, executive
officer  base  salaries  have  only  been  adjusted  to be  consistent  with the
Company's overall compensation targets based on survey data.

         The survey data considered by the Compensation Committee in determining
1997  executive   compensation   include  salary  information  provided  by  103
biotechnology  enterprises  having between 51 and 149 employees (the "Comparison
Group"),  of which 82 are publicly traded companies.  Approximately 65% of these
publicly traded companies are included in the Nasdaq  Pharmaceutical Stock Index
referred to in the Stock Price  Performance Graph that appears elsewhere in this
Proxy Statement.

Annual Bonus

         An annual bonus plan has been  established to reward  participants  for
their  contributions to the achievement of Company-wide  performance  goals. All
executive  officers  of  the  Company  participate  in  the  program,   and  the
Compensation  Committee may expand it to cover other  employees.  This incentive
plan is designed to ensure that when such payments are added to a  participant's
base salary,  the  resultant  compensation  for above average  performance  will
approximate the average total cash compensation level of comparable companies.

         In 1997,  executive officers were eligible to earn a bonus up to 25% of
salary,  upon attainment of specific Company  performance goals set by the Board
of  Directors.  These goals  included  forming  strategic  alliances,  achieving
product  milestones,  and increasing cash reserves.  The Compensation  Committee
does not assign relative weights to these goals in formulating the amount of the
awards. In February 1998, the Compensation  Committee  determined that the goals
for 1997 were met by the executive officers.  Bonuses for 1997 were paid in 1998
and were approximately 25% of base executive compensation.

         In addition to the bonus plan, the  Compensation  Committee has the
discretion  to  grant  achievement  awards  of  cash  and/or  stock  options  to
individual  executive  officers.   These  achievement  awards  are  intended  to

                                       10
<PAGE>

recognize an individual for  outstanding  contributions  to the Company.  During
1997, Mr. Anderson, Dr. Reno and Dr. Schroff received achievement awards.

Stock Options

         Stock options are viewed as a basic  element of the total  compensation
program and emphasize  long-term Company performance as measured by the creation
of shareholder value. Options under the Company's existing stock option plan are
granted  to  all  employees.   In  determining  the  size  of  the  grants,  the
Compensation Committee considers the amount and value of options currently held,
but focuses primarily on the executive's past and likely continued  contribution
to the Company, as well as the executive's relative position within the Company.
Although the  Compensation  Committee does not have a target ownership level for
Common  Stock  holdings  by  executives  and  key  employees,  the  Compensation
Committee's  objectives  are to enable such  persons to develop  and  maintain a
significant long-term ownership position in the Common Stock.

         Stock  options to executive  officers have been granted at 100% of fair
market value on the date of grant. The Company has generally  awarded options to
executives  at the  time  of  employment  and  promotion,  and at  discretionary
intervals  thereafter.  The  Compensation  Committee seeks to keep its executive
stock option compensation competitive with other biotechnology companies.  Stock
option  exercisability  is determined  by the  Compensation  Committee.  Options
become  exercisable  in periods  generally  ranging from one to nine years after
date of grant.  In certain cases,  exercisability  may be  accelerated  based on
achievement of corporate and individual objectives.

         In  addition  to  granting  stock  options  to  the  Company's  current
executive  officers under the programs described above, the Company also granted
152,500 stock options to  approximately  32 other  employees under the Company's
Restated 1994 Stock Option Plan. This broad-based  program is designed to create
in the Company an entrepreneurial spirit and to provide broad incentives for the
day-to-day  achievements  of these  employees,  which,  in turn,  is expected to
improve the Company's long-term performance.

Compensation of the Chief Executive Officer

         In determining the base salary compensation of Dr. Abrams for 1997, the
Compensation  Committee  considered  the same  factors that it  considered  when
determining compensation for all employees and for the Company's other executive
officers,  including  the Company's  performance  as a whole.  Dr.  Abrams' base
salary  compensation  received  in 1997 was  $274,149,  which  placed him at the
average of chief  executive  officers  in the Radford  Associates  Biotechnology
Survey.

Submitted by the Compensation Committee of the Board of Directors

James G. Andress
Jack L. Bowman
Lawrence H.N. Kinet

                                       11


<PAGE>


Stock Price Performance Graph

         The graph below compares the cumulative total shareholder return on the
Company's  Common  Stock with the  cumulative  total  shareholder  return of the
Nasdaq Stock Market Index (US) and the Nasdaq Pharmaceutical Stocks Index.

         Note:  Stock  price  performance  shown  below for the  Company is
historical, and not necessarily indicative of future price performance.
<TABLE>
<CAPTION>


           Comparison of Five-Year Cumulative Total Return Among NeoRx
                 Corporation, Nasdaq Stock Market Index (US) and
                      Nasdaq Pharmaceutical Stocks Index(1)

                                     12/31/92   12/31/93   12/31/94   12/31/95   12/31/96   12/31/97
                                     --------   --------   --------   --------   --------   --------
<S>                                   <C>        <C>        <C>        <C>        <C>        <C>
NeoRx Corporation                     $100       $ 62       $  33      $  43      $  28      $  38
Nasdaq Stock Market Index (US)         100        115         112        159        195        240
Nasdaq Pharmaceutical Stock Index      100         89          67        123        123        127
<FN>

(1)  Assumes  $100  invested on December  31, 1992 in NeoRx  Corporation  Common
     Stock, the Nasdaq Stock Market Index and the Nasdaq  Pharmaceutical  Stocks
     Index,  an index of  approximately  217 companies,  the stocks of which are
     quoted on the Nasdaq National Market,  and the Primary Standard  Industrial
     Classification  Code  Number  (SIC)  of  which  is  #283  -  Pharmaceutical
     Companies.  Total return  performance for the Nasdaq Stock Market Index and
     the Nasdaq  Pharmaceutical  Stocks  Index is  weighted  based on the market
     capitalization  of the  firms  included  in each  index  and  assumes  that
     dividends  are  reinvested.  The Nasdaq  Stock  Market Index and the Nasdaq
     Pharmaceutical  Stocks Index are  produced and  published by the Center for
     Research in Securities Pricing at the University of Chicago.
</FN>
</TABLE>

                                       12

<PAGE>



Employment and Change of Control Agreements and Severance Agreements

         Each of the  executive  officers of the Company has an  agreement  that
defines terms of employment  and change of control of the Company (as defined in
the   agreement).   A  change  of  control  occurs  through   certain   mergers,
consolidations, acquisitions of property or stock, liquidations, reorganizations
or sales of substantially all the assets of the Company.  The executive officers
may receive 12 months'  salary and a  proportioned  bonus if earned.  Also,  the
vesting of all options  outstanding  under the Company's  1984 Stock Option Plan
and Restated 1994 Stock Option Plan will be accelerated  and optionees will have
the right to exercise  all or a part of such  options  immediately  prior to any
such transaction.  Any unexercised  options will terminate,  except that, in the
event of a merger in which the shareholders of the Company receive capital stock
of  another  corporation,  such  unexercised  options  must  be  assumed  or  an
equivalent  option is  substituted  by the successor  corporation.  A qualifying
termination  under this agreement also is considered to occur when the executive
officers'  responsibilities  or authority are materially  reduced on more than a
short-term  basis.  These agreements  automatically  renew  biannually  absent a
notice of nonrenewal by either party.

         The Company also has severance  agreements with each executive  officer
that provides that the executive  officer would receive up to 12 months'  salary
if such  executive  officer is  terminated  "without  cause" (as defined in each
agreement). The severance agreements allow the Company to reduce payments to the
former executive officers who undertake consulting or employment elsewhere.  The
agreements define severance without cause to include a material reduction in the
executive officer's responsibility or authority.  These agreements automatically
renew bi-annually absent a notice of nonrenewal by either party.

Certain Relationships and Related Transactions

         On July 7, 1993, Dr. Frederick B. Craves, the Company's Chairman of the
Board of  Directors,  entered  into a  consulting  agreement  with  the  Company
providing that Dr. Craves shall be retained as a general  advisor and consultant
to the Company's management on all matters pertaining to the Company's business.
In  exchange  for such  services,  Dr.  Craves is  compensated  $30,000 for each
calendar quarter of services, plus reasonable travel and other expenses. On July
7, 1993, the Company also granted Dr. Craves an option to purchase a total of up
to  125,000  shares  of Common  Stock  over four  years.  In 1996,  the Board of
Directors  accelerated  vesting of Dr.  Craves'  remaining  40,000 shares of the
option grant for his assistance in NeoRx's 1996 financing. On February 21, 1997,
the Board of Directors granted to Dr. Craves an option to purchase 60,000 shares
of the  Company's  Common Stock from the Restated 1994 Stock Option Plan for his
services as Chairman  of the Board of  Directors.  The option was granted at the
then current  market price of the Common  Stock and becomes  exercisable  in two
equal installments  beginning one year after the date of grant. If Dr. Craves is
terminated  "without  cause" (as  defined in the  consulting  agreement),  he is
entitled to a pro rata portion of the  quarterly fee for services up to the date
of  termination,  all expenses  incurred up to such date, and a payment equal to
three months of service.

                                       13
<PAGE>

         In November 1995 and April 1996, the Company loaned Dr. Paul G. Abrams,
the  Company's  President  and Chief  Executive  Officer,  a total of  $140,000,
bearing  interest at the applicable  federal rate. The balance of loans due from
Dr. Abrams to the Company at December 31, 1997 is $111,938 and is due on demand.
Dr.
Abrams is repaying the loans in monthly payments.

Compliance With Section 16(a) of the Securities Exchange Act of 1934

         Section  16(a) of the  Securities  Exchange  Act of 1934,  as  amended,
requires the Company's  Directors and  executive  officers,  and persons who own
more than 10% of a registered  class of the Company's  securities,  to file with
the SEC the initial  reports of ownership and reports of changes in ownership of
Common Stock and other equity  securities of the Company.  Directors,  executive
officers and  greater-than-10%  shareholders  are required by SEC regulations to
furnish the Company with copies of all Section 16(a) forms they file.

         Based solely on its review of the copies of such forms it received,  or
written  representations  from certain reporting persons that no such forms were
required for those  persons,  the Company  believes  that during 1997 all filing
requirements  required  by Section  16(a)  applicable  to  Directors,  executive
officers and  greater-than-10%  shareholders were complied with by such persons,
other than a late Form 3 filed by Richard L. Anderson and a late Form 4 filed by
Frederick B. Craves.

Relationship with Auditor

         On  April  4,  1997,   the  Company's   Board  of  Directors,   at  the
recommendation  of its Audit  Committee,  terminated  the  engagement  of Arthur
Andersen LLP and selected KPMG Peat Marwick LLP as the Company's auditor.

         The report of Arthur Andersen LLP on the Company's Financial Statements
for  either  of the last two years  did not  contain  an  adverse  opinion  or a
disclaimer of opinion and was not qualified or modified as to uncertainty, audit
scope, or accounting principles.  During the Company's two most recent years and
subsequent  interim periods  preceding the date of termination of the engagement
of Arthur  Andersen  LLP, the Company was not in  disagreement  on any matter of
accounting principles or practices,  financial statement disclosure, or auditing
scope or procedure,  which disagreement,  if not resolved to the satisfaction of
Arthur  Andersen LLP, would have caused Arthur Andersen LLP to make reference to
the subject matter of the disagreement in connection with its report.

         The Company has not consulted with KPMG Peat Marwick LLP during its two
most  recent  years  nor  during  any  subsequent  interim  period  prior to its
engagement  regarding the  application  of accounting  principles to a specified
transaction,  either  completed or proposed,  or the type of audit  opinion that
might be rendered on the Company's financial statements.

         The  Board of  Directors  has  selected  KPMG Peat  Marwick  LLP as the
Company's  auditors  for 1998.  Representatives  from KPMG Peat  Marwick LLP are
expected  to be  present at the Annual  Meeting to make a  statement  if they so
desire and to respond to appropriate questions from shareholders.

                                       14
<PAGE>


                            PROPOSALS OF SHAREHOLDERS

         Under the Company's Bylaws, shareholders seeking to propose business to
be conducted at an annual  meeting of  shareholders  must give written notice to
the Company no later than the date that  shareholder  nominations  for Directors
must be received. The notice must contain certain information as to the proposal
and  the  shareholder,  including  the  shareholder's  share  ownership  and any
financial interest of the shareholder in the proposal.  Any proposal not made in
compliance  with the  Bylaws  may be  rejected  by the  Board of  Directors.  No
shareholder proposals for the Annual Meeting had been received by the Company as
of the date of this Proxy Statement.

         A  shareholder  who  intends to present a proposal  at the 1999  Annual
Meeting of Shareholders and desires that  information  regarding the proposal be
included  in the 1999 proxy  statement  and form of proxy must  ensure that such
information is received by the Company no later than November 27, 1998.

                                 OTHER BUSINESS

         The Company  knows of no other  business to be  presented at the Annual
Meeting.  If any other business properly comes before the Annual Meeting,  it is
intended  that the  shares  represented  by proxies  will be voted with  respect
thereto  in  accordance  with  the best  judgment  of the  persons  named in the
accompanying form of proxy.

         Upon written request from any person  solicited herein addressed to the
Company's Corporate  Secretary at the Company's  principal offices,  the Company
will  provide,  at no cost, a copy of the  Company's  Form 10-K Annual Report as
filed with the SEC for the year ended December 31, 1997.

                                  BY ORDER OF THE BOARD OF DIRECTORS



                                  RICHARD L. ANDERSON
                                  Senior Vice President, Finance and Operations
                                  Chief Financial Officer, Secretary

March 24, 1998
Seattle, Washington

                                       15
<PAGE>

                                     PROXY

                               NEORX CORPORATION
                  PROXY FOR THE ANNUAL MEETING OF SHAREHOLDERS
                            TO BE HELD MAY 13, 1998
          THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

The undersigned hereby appoints Richard L. Anderson as Proxy, with full power of
substitution,  and hereby authorizes him to represent and to vote, as designated
below, all the shares of Common Stock of NeoRx Corporation held of record by the
undersigned on March 16, 1998, at the Annual Meeting of  Shareholders to be held
on May 13, 1998, or any adjournment or postponement  thereof.  (Continued and to
be signed on reverse side.)

FOLD AND DETACH HERE

FOR all nominees (except as marked to the contrary)  WITHHOLD  AUTHORITY to vote
for all nominees.

1. ELECTION OF DIRECTORS
Election of the following six nominees to serve as
Directors for the ensuing year or until their successors
are elected and qualified:
Nominees: Paul G. Abrams, Jack L. Bowman,
Frederick B. Craves, Mary C. Foerster, Alan A. Steigrod and E. Rolland Dickson.

INSTRUCTIONS:  To withhold authority to vote for any individual  nominee,  write
the name(s) of the nominee(s) below: Unless otherwise  directed,  all votes will
be apportioned equally among those persons for whom authority is given to vote.

Your vote is  important.  Prompt  return of this  proxy  card will help save the
expense of additional solicitation efforts.

Signature(s)   Dated:   , 1998
Please sign above exactly as your name appears on your stock  certificate.  When
shares are held  jointly,  each person  should  sign.  When signing as attorney,
executor, administrator, trustee or guardian, please give full title as such. An
authorized  person  should  sign on behalf  of  corporations,  partnerships  and
associations and give his or her title.

FOLD AND DETACH HERE


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